Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Atamaniuk, J; Vidotto, C; Kinzlbauer, M; Bachl, N; Tiran, B; Tschan, H.
Cell-free plasma DNA and purine nucleotide degradation markers following weightlifting exercise.
EUR J APPL PHYSIOL. 2010; 110(4): 695-701.
Doi: 10.1007/s00421-010-1532-5
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- Co-authors Med Uni Graz
- Tiran Beate
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- Abstract:
- The present study aimed to investigate the acute effects of a single bout of high-intensive strength training on the production of cell-free plasma DNA (cf-DNA), as well as on the degradation of purine nucleotides as assessed by the concentration of xanthine (XA) and hypoxanthine (HX) in urine and serum. Twelve trained weightlifters performed six sets of six lifting exercises with 90-95% of the one repetition maximum. Blood samples and urine were obtained 1 h before training, immediately after finishing the exercise session and following 2 h of recovery. Cf-DNA, HX, and XA (in serum) significantly increased (P < 0.05-P < 0.001) immediately after heavy lifting exercise when compared with baseline levels, and significantly decreased (P < 0.05-P < 0.001) after 2 h of recovery. These results indicate that, cf-DNA and oxypurines might be relevant biomarkers for cellular damage, mechanical, energetic, and/or ischemic stress in context with exercise.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Biological Markers - metabolism
- Cell-Free System -
- DNA - blood
- DNA Damage - physiology
- Exercise - physiology
- Female -
- Humans -
- Hypoxanthine - blood
- Oxidation-Reduction -
- Purine Nucleotides - metabolism
- Weight Lifting - physiology
- Young Adult -
- Find related publications in this database (Keywords)
- Cell-free plasma DNA
- Oxypurines
- Muscle damage
- Resistance exercise
- Weightlifting