Selected Publication:
Pieber, TR; Brunner, GA; Schnedl, WJ; Schattenberg, S; Kaufmann, P; Krejs, GJ.
Evaluation of a structured outpatient group education program for intensive insulin therapy.
Diabetes Care. 1995; 18(5):625-630
Doi: 10.2337/diacare.18.5.625
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- Leading authors Med Uni Graz
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Pieber Thomas
- Co-authors Med Uni Graz
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Brunner Gernot
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Krejs Günter Josef
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Schnedl Wolfgang
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- Abstract:
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To determine the efficacy and safety of a structured diabetes teaching and treatment program (DTTP) in patients with insulin-dependent diabetes mellitus (IDDM) in an outpatient setting.
All patients with IDDM who completed a structured 5-day outpatient DTTP were reevaluated after a mean follow-up of 3 years. A standardized interview was used to assess frequency of severe hypoglycemia, type of insulin treatment, self-monitoring, and other diabetes-related parameters. HbA1c was measured by high-performance liquid chromatography.
Of 205 patients, 4 (2%) died during the observation period. HbA1c in the 201 surviving patients decreased significantly from 8.7 +/- 2.0 to 7.5 +/- 1.2% at follow-up (P < 0.001); frequency of severe hypoglycemia decreased from a mean of 0.46 to 0.13 per patient per year (P < 0.001). Hospital admission due to acute metabolic disturbances decreased from 4.5 +/- 11.1 to 1.4 +/- 6.7 days/patient-year (P < 0.001). At follow-up, intensive insulin therapy was carried out by 98% of the patients, and 80% of the patients reported three or more measurements of blood glucose per day. Diabetes-related knowledge had a positive (P < 0.01) and body mass index a negative (P < 0.02) influence on improving HbA1c assessed by multiple regression analysis. Severe hypoglycemia after DTTP was associated with a history of severe hypoglycemia before DTTP (P < 0.001) and the existence of overt diabetic nephropathy (P < 0.05).
A structured outpatient DTTP as used in this study is able to improve overall metabolic control and decrease the frequency of severe hypoglycemia in patients with IDDM.
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Adult -
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Blood Glucose - analysis
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Blood Glucose Self-Monitoring -
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Diabetes Mellitus, Type 1 - blood
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Diabetes Mellitus, Type 1 - drug therapy
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Glycated Hemoglobin A - analysis
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Humans -
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Hypoglycemia - prevention & control
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Insulin - therapeutic use
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Middle Aged -
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Outpatients -
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Patient Education as Topic -
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Regression Analysis -