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HEALTHY AIMS: Implantable micro-sensors and micro-systems for ambulatory measurement and control in medical products.

Abstract
In this project key microsystem technologies and communication methods will be developed that bring intelligence directly to the human, in the form of medical implants and ambulatory measurement systems, and also enable information from these devices to be transmitted out into the wider environment. The microsystem technologies to be developed can be applied to any generic Ambient intelligent' system comprising sensors, actuators, an intelligent processor and a wiring loom. The medical applications have been chosen for 2 reasons. Firstly, they will progress the existing State of the Art in Microsystems in terms of size, reliability, and power constraints far more than many other application sectors. In addition there will be a direct positive impact into the health of EU citizens. The overall objective is to develop the technologies that go to make up a microsystem, and then produce specific medical devices to exploit these technologies. The 4 year project, with 26 partners, is structured with the focus on the microsystem technology development, most of which doesn't include silicon. Thin is seen as crucial if complete microsystems are to be realised in the coming few years. The project includes participants from all of the disciplines necessary to produce a complete generic microsystem. The result will be a range of core technologies and medical devices utilising these core technologies. Intelligence will be given back to people where part of their own internal system has failed. Quality of life will be improved for millions of EU citizens and the long term cost of treating people will reduce sinificantly. The resulting final medical products include cochlear and retina implants, nerve stimulation, bladder control and blood monitoríng systems. It is estimated from the available statistics that around 50% of the western poulation i.e. around 500 million citizens, will suffer from at least one of the health problems targeted in this project.
Local Subprojectlead:
Velikay-Parel Michaela
Duration:
01.06.2004-31.05.2008
Programme:
EU (FP-6)
Subprogramme
TP2: Information Society Technologies
EU-Project Instruments
Integrated Project (IP)
Type of Research
applied research
Staff
Velikay-Parel, Michaela, Project Leader
MUG Research Units
Department of Ophthalmology
Project partners
Assuta Medical Centers Ltd, Israel
Campus Micro Technologies GmbH, Germany
Central Research Laboratories Ltd, United Kingdom
Cochlear Technology Centre, Belgium
DINAMIC Technology Innovation Centre, Spain
Ecole Polytechnique Federale de Lausanne, Switzerland
European Technology for Business Limited, United Kingdom
IIP-Technologies Gmbh, Germany
Institut für Mikro- und Informationstechnik der Hahn-Schickard-Gesellschaft (HSG-IMIT), Germany
Institute of Electron Technology, Poland
Interuniversitaire Micro-Electronica Centrum vzw, Belgium
Mediplus Ltd, United Kingdom
microTEC Gesellschaft für Mikrotechnologie mbH, Germany
NEXUS, France
North Bristol NHS Trust, United Kingdom
Queen Mary and Westfield College University of London, United Kingdom
Saft SA, France
Salisbury District Hospital, United Kingdom
TWI Ltd, United Kingdom
University of Freiburg, Germany
University of Newcastle upon Tyne, United Kingdom
University of Salford, United Kingdom
VDI/VDE-IT, Germany
Zarlink Semiconductor Ltd, United Kingdom
Funded by
Europäische Kommission, Rue de la Loi, Brussels, Belgium
Project results published
> Retina Implants... In: Inmann,A; Hodgins,D editors(s). Implantable Sensor Systems for Medical Applications. WPB (52) : Cambridge, UK: Woodhead Publishing Ltd; p. 469-496. 2013(ISBN: 978-84569-987-1)
> Visual perception in Artificial vision... Spektrum der Augenheilkunde. 2013; 27(6):235--Festtagung 150 Jahre Univeristäts-Augenklinik Graz; Dec 7,2013; Graz.
> Tolerance of porcine eyes to epiretinal prostheses... ACTA OPHTHALMOL. 2011; 89(6): E540-E541.
> Perceptual threshold and neuronal excitability as ... Invest Ophthalmol Vis Sci . 2011; 52(E-Abst):2590.-ARVO; MAY 1-5,2011; Fort Lauderdale.
> Perceptual threshold and neuronal excitability as ... Acta opthalmologica. 2010; 2010: -EVER; OCT 6-9,2010; Heraklion, GREECE.
> Validation of Modified Grating Test as a visual ac... EVER2009; -European Association for Vision and Eye Research ; SEPT 30 - OCT 3, 2009 ; Portoroz, SLOVENIA.
> Investigation of particular surgical steps in epir... EVER2009; -European Association for Vision and Eye Research ; SEPT 30 - OCT 3, 2009 ; Portoroz, SLOVENIA.
> Visusabhängige Bewältigungsstrategien eines funkti... 50. Tagung der Österreichischen Ophthalmologischen Gesellschaft2009; -ÖOG; MAI 21-23, 2009; Bad Ischl, AUSTRIA.
> First experience with The IRIS retinal implant sys... EVER2009; -European Association for Vision and Eye Research ; SEPT 30 - OCT 3, 2009 ; Portoroz, SLOVENIA.
> A new method for fixation and explantation of epir... Invest Ophthalmol Vis Sci . 2009; 50(E-Ab):4571--ARVO; MAI 3-7, 2009; Ft Lauderdale, Florida, USA.
> Artificial vision, a new technology for the blind... Symposium Proceedings. 2008; 98-108.-Maribor International ophthalmological Symposium; 1.2.2008; marburg. (ISBN: 9789616575355 )
> First results in repeated functional testing in lo... European Association for Vision and Eye Research2008; -EVER; OCT 1-4, 2008; Portoroz, SLOVENIA.
> The suitability of normally sighted subjects with ... Invest. Ophthalmol. Vis. Sci. 2007 48: E-Abstract 6702007; -ARVO; MAI 6-10, 2007; Fort Lauderdale, Florida, USA.
> Repeated mobility testing in low vision patients w... Vis. Sci. 2007 48: E-Abstract 25552007; -ARVO; MAI 6-10, 2007; Fort Lauderdale, Florida, USA.
> Update on artificial Vision with the IMI Implant ... Vitreoretinales Vail- Meeting; 14. 3.2007; USA, Colorado, Vail. 2007.
> Repeated mobility testing for later artificial vis... J Neural Eng. 2007; 4(1): S102-S107.
> Netzhautimplantate und Artificial Vision... 41. Symposium über Strabologie, Pädiatrische-/Neuroophthalmologie. 2007; -41. Symposium über Strabologie, Pädiatrische-/Neuroophthalmologie; OKT 12-14; Bozen, SÜDTIROL.
> Neuster Stand der Retinaimplantate... Österreichischer Blindenverband ; Juni, 22.2007 ; Wien. 2007.
> Neuster Stand der Retinaimplantate ... Blindenvereinigung NÖ: ; 2.3.2007 ; Wiesmath. 2007.
> Lichtblicke für Blinde... Steiermark Innovativ ; Graz: Leykam Verlag; 2007. pp. 60-61.
> A new method for fixation and explantation of epir... European Journal of Ophthalmology2007; Vol. 17(Supp):-Joint congress of SOE/AAO; JUN 9-12, 2007; Vienna, AUSTRIA.
> Repeated mobility and visual acuity testing in low... European Journal of Ophthalmology2007; Vol. 17(Supp):-Joint congress of SOE/AAO; JUN 9-12, 2007; Vienna, AUSTRIA.
> An update in retinal prosthesis... 30. Congress of the Alpe-Adria International Ophthalmological Society2007; MAI 4-5, 2007; Split, CROATIA.
> Low vision tests in artificial vision... 30. Congress of the Alpe-Adria International Ophthalmological Society2007; MAI 4-5, 2007; Split, CROATIA.
> Retina Implantate: aktueller Stand des Artificial ... Spektrum der Augenheilkunde. 2006; 20: 211-214.
> A test battery for visual function and performance... Invest Ophthalmol Vis Sci. ARVO E-Abstract 3205; 47: -ARVO; 31.4.-4.5.2006; USA.
> The pig as an animal model for retinal chip implan... Invest Ophthalmol Vis Sci. 47 E-Absract 3164: -Association for Research in Vision and Ophthalmology (ARVO); MAI, 2006; Fort Lauderdale, Florida, USA.
> Early Clinical Experience with A Chronic Retinal I... Invest Ophthalmol Vis Sci. 47 E-Abstract 3216 : -ARVO; MAI, 2006; Fort Lauderdale, Florida, USA.
> Stand der retinalen Implantate... steirische Fachgruppensitzung; 11.9.2006 ; Graz. 2006.
> Der Netzhautchip für Blinde... Fachgruppentreffen der kärtner Augenärzte; 4.11.2006 ; Klagenfurt. 2006.
> Neuer Mobilitätstest und Wahrnehmungstest zur Erfa... Spektrum der Augenheilkunde. 2006; 20(4): 180-184.
> Der Netzhaut Chip- Retina Implantate für Blinde... Vereinigung sehbehinderter und hörbehinderter Menschen; 12.11.2006 ; Wien. 2006.
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