Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Vosberg Sebastian |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2022
Originalarbeit (Zeitschrift)
** Boos, SL; Loevenich, LP; Vosberg, S; Engleitner, T; Öllinger, R; Kumbrink, J; Rokavec, M; Michl, M; Greif, PA; Jung, A; Hermeking, H; Neumann, J; Kirchner, T; Rad, R; Jung, P
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
Cell Mol Gastroenterol Hepatol. 2022; 13(2): 517-540.
Doi: 10.1016/j.jcmgh.2021.10.008
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Kerbs, P; Vosberg, S; Krebs, S; Graf, A; Blum, H; Swoboda, A; Batcha, AMN; Mansmann, U; Metzler, D; Heckman, CA; Herold, T; Greif, PA
Fusion gene detection by RNA-sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements.
Haematologica. 2022; 107(1): 100-111.
Doi: 10.3324/haematol.2021.278436
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Wirth, AK; Wange, L; Vosberg, S; Henrich, KO; Rausch, C; Özdemir, E; Zeller, CM; Richter, D; Feuchtinger, T; Kaller, M; Hermeking, H; Greif, PA; Senft, D; Jurinovic, V; Bahrami, E; Jayavelu, AK; Westermann, F; Mann, M; Enard, W; Herold, T; Jeremias, I
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance.
Leukemia. 2022; 36(12):2863-2874
Doi: 10.1038/s41375-022-01726-7
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Kurzbericht/Letter
** Dill, V; Wagner, CV; Keller, EC; Fernandez-Hernandez, FJ; Shoumariyeh, K; Odinius, TO; Buschhorn, L; Hauch, RT; Suren, C; Hecker, JS; Herhaus, P; Sandherr, M; Schmidt, B; Slotta-Huspenina, J; Bassermann, F; Höckendorf, U; Jilg, S; Branca, C; Vosberg, S; Jost, PJ
Elevated RIPK3 correlates with disease burden in myelofibrosis.
Blood Adv. 2022;
Doi: 10.1182/bloodadvances.2021006838
PubMed
FullText
FullText_MUG
Abstract (Zeitschrift)
** Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; McGranahan, N; Jost, P
Inflammatory cell death acts as tumor suppressor in lung adenocarcinoma
INTERNIST. 2022; 63(SUPPL 3):338-339.
[Oral Communication]
Web of Science
** Dutta, S; Kerbs, P; Rothenberg-Thurley, M; Ksienzyk, B; Krebs, S; Blum, H; Spiekermann, K; Metzeler, KH; Herold, T; Vosberg, S; Greif, PA
Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature
BLOOD. 2022; 140: 8912-8913.
Doi: 10.1182/blood-2022-168939
Web of Science
FullText
FullText_MUG
** Ruhnke, L; Frimmel, J; Rollig, C; Mohr, B; Altmann, H; Poitz, D; Zukunft, S; Schranz, K; Vosberg, S; Spiekermann, K; von Bergwelt, M; Jost, E; Dressler, S; Schafer-Eckart, K; Chavakis, T; Aust, D; Johrens, K; Baretton, G; Bornhauser, M; Greif, PA; Stolzel, F; Herold, S; Wagenfuhr, L
Prevalence, Clinical and Molecular Features, and Prognostic Value of Tetraploidy/Near-Tetraploidy in Patients with Acute Myeloid Leukemia
BLOOD. 2022; 140: 3454-3455.
Doi: 10.1182/blood-2022-166271
Web of Science
FullText
FullText_MUG
2021
Originalarbeit (Zeitschrift)
** Giacopelli, B; Wang, M; Cleary, A; Wu, YZ; Schultz, AR; Schmutz, M; Blachly, JS; Eisfeld, AK; Mundy-Bosse, B; Vosberg, S; Greif, PA; Claus, R; Bullinger, L; Garzon, R; Coombes, KR; Bloomfield, CD; Druker, BJ; Tyner, JW; Byrd, JC; Oakes, CC
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Genome Res. 2021; 31(5): 747-761.
Doi: 10.1101/gr.269233.120
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Moser, C; Jurinovic, V; Sagebiel-Kohler, S; Ksienzyk, B; Batcha, AMN; Dufour, A; Schneider, S; Rothenberg-Thurley, M; Sauerland, CM; Görlich, D; Berdel, WE; Krug, U; Mansmann, U; Hiddemann, W; Braess, J; Spiekermann, K; Greif, PA; Vosberg, S; Metzeler, KH; Kumbrink, J; Herold, T
A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.
Blood Adv. 2021; 5(22):4752-4761
Doi: 10.1182/bloodadvances.2021004814
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Schänzer, A; Achleitner, MT; Trümbach, D; Hubert, L; Munnich, A; Ahlemeyer, B; AlAbdulrahim, MM; Greif, PA; Vosberg, S; Hummer, B; Feichtinger, RG; Mayr, JA; Wortmann, SB; Aichner, H; Rudnik-Schöneborn, S; Ruiz, A; Gabau, E; Sánchez, JP; Ellard, S; Homfray, T; Stals, KL; Wurst, W; Neubauer, BA; Acker, T; Bohlander, SK; Asensio, C; Besmond, C; Alkuraya, FS; AlSayed, MD; Hahn, A; Weber, A
Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism.
Ann Neurol. 2021; 90(1): 143-158.
Doi: 10.1002/ana.26127
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Abstract (Zeitschrift)
** Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; Branca, C; McGranahan, N; Jost, PJ
RIPK3 downregulation in lung cancer alters the tumor immune micro-environment supporting tumor progression
ONCOL RES TREAT. 2021; 44: 51-52.
Web of Science
** Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; McGranahan, N; Jost, PJ
Necroptosis establishes an inflammatory tumor immune microenvironment acting as tumor suppressor in lung adenocarcinoma
ANN ONCOL. 2021; 32: S945-S945.
Doi: 10.1016/j.annonc.2021.08.1788
[Poster]
Web of Science
FullText
FullText_MUG
2020
Originalarbeit (Zeitschrift)
** Opatz, S; Bamopoulos, SA; Metzeler, KH; Herold, T; Ksienzyk, B; Bräundl, K; Tschuri, S; Vosberg, S; Konstandin, NP; Wang, C; Hartmann, L; Graf, A; Krebs, S; Blum, H; Schneider, S; Thiede, C; Middeke, JM; Stölzel, F; Röllig, C; Schetelig, J; Ehninger, G; Krämer, A; Braess, J; Görlich, D; Sauerland, MC; Berdel, WE; Wörmann, BJ; Hiddemann, W; Spiekermann, K; Bohlander, SK; Greif, PA
The clinical mutatome of core binding factor leukemia.
Leukemia. 2020; 34(6): 1553-1562.
Doi: 10.1038/s41375-019-0697-0
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Stief, SM; Hanneforth, AL; Weser, S; Mattes, R; Carlet, M; Liu, WH; Bartoschek, MD; Domínguez Moreno, H; Oettle, M; Kempf, J; Vick, B; Ksienzyk, B; Tizazu, B; Rothenberg-Thurley, M; Quentmeier, H; Hiddemann, W; Vosberg, S; Greif, PA; Metzeler, KH; Schotta, G; Bultmann, S; Jeremias, I; Leonhardt, H; Spiekermann, K
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
Leukemia. 2020; 34(1): 50-62.
Doi: 10.1038/s41375-019-0497-6
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
2019
Originalarbeit (Zeitschrift)
** Bastian, L; Schroeder, MP; Eckert, C; Schlee, C; Tanchez, JO; Kämpf, S; Wagner, DL; Schulze, V; Isaakidis, K; Lázaro-Navarro, J; Hänzelmann, S; James, AR; Ekici, A; Burmeister, T; Schwartz, S; Schrappe, M; Horstmann, M; Vosberg, S; Krebs, S; Blum, H; Hecht, J; Greif, PA; Rieger, MA; Brüggemann, M; Gökbuget, N; Neumann, M; Baldus, CD
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
Leukemia. 2019; 33(8): 1895-1909.
Doi: 10.1038/s41375-019-0430-z
Web of Science
PubMed
FullText
FullText_MUG
Übersichtsarbeit
** Vosberg, S; Greif, PA
Clonal evolution of acute myeloid leukemia from diagnosis to relapse.
Genes Chromosomes Cancer. 2019; 58(12): 839-849.
Doi: 10.1002/gcc.22806
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
2018
Originalarbeit (Zeitschrift)
** Greif, PA; Hartmann, L; Vosberg, S; Stief, SM; Mattes, R; Hellmann, I; Metzeler, KH; Herold, T; Bamopoulos, SA; Kerbs, P; Jurinovic, V; Schumacher, D; Pastore, F; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Graf, A; Krebs, S; Blum, H; Neumann, M; Baldus, CD; Bohlander, SK; Wolf, S; Görlich, D; Berdel, WE; Wörmann, BJ; Hiddemann, W; Spiekermann, K
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
Clin Cancer Res. 2018; 24(7): 1716-1726.
Doi: 10.1158/1078-0432.CCR-17-2344
Web of Science
PubMed
FullText
FullText_MUG
** Schranz, K; Hubmann, M; Harin, E; Vosberg, S; Herold, T; Metzeler, KH; Rothenberg-Thurley, M; Janke, H; Bräundl, K; Ksienzyk, B; Batcha, AMN; Schaaf, S; Schneider, S; Bohlander, SK; Görlich, D; Berdel, WE; Wörmann, BJ; Braess, J; Krebs, S; Hiddemann, W; Mansmann, U; Spiekermann, K; Greif, PA
Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia.
Oncotarget. 2018; 9(53): 30128-30145.
Doi: 10.18632/oncotarget.25729
[OPEN ACCESS]
PubMed
FullText
FullText_MUG
Kurzbericht/Letter
** Vosberg, S; Hartmann, L; Metzeler, KH; Konstandin, NP; Schneider, S; Varadharajan, A; Hauser, A; Krebs, S; Blum, H; Bohlander, SK; Hiddemann, W; Tischer, J; Spiekermann, K; Greif, PA
Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load.
Haematologica. 2018; 103(12): e581-e584-e581-e584.
Doi: 10.3324/haematol.2018.193102
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
2017
Originalarbeit (Zeitschrift)
** Herold, T; Metzeler, KH; Vosberg, S; Hartmann, L; Jurinovic, V; Opatz, S; Konstandin, NP; Schneider, S; Zellmeier, E; Ksienzyk, B; Graf, A; Krebs, S; Blum, H; Cristina Sauerland, M; Büchner, T; Berdel, WE; Wörmann, BJ; Mansmann, U; Hiddemann, W; Bohlander, SK; Spiekermann, K; Greif, PA
Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.
Genes Chromosomes Cancer. 2017; 56(1): 75-86.
Doi: 10.1002/gcc.22418
Web of Science
PubMed
FullText
FullText_MUG
** von der Heide, EK; Neumann, M; Vosberg, S; James, AR; Schroeder, MP; Ortiz-Tanchez, J; Isaakidis, K; Schlee, C; Luther, M; Jöhrens, K; Anagnostopoulos, I; Mochmann, LH; Nowak, D; Hofmann, WK; Greif, PA; Baldus, CD
Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients.
Leukemia. 2017; 31(5): 1069-1078.
Doi: 10.1038/leu.2016.324
Web of Science
PubMed
FullText
FullText_MUG
** Woischke, C; Schaaf, CW; Yang, HM; Vieth, M; Veits, L; Geddert, H; Märkl, B; Stömmer, P; Schaeffer, DF; Frölich, M; Blum, H; Vosberg, S; Greif, PA; Jung, A; Kirchner, T; Horst, D
In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components.
Mod Pathol. 2017; 30(1): 95-103.
Doi: 10.1038/modpathol.2016.150
Web of Science
PubMed
FullText
FullText_MUG
Kurzbericht/Letter
** Silva, P; Neumann, M; Schroeder, MP; Vosberg, S; Schlee, C; Isaakidis, K; Ortiz-Tanchez, J; Fransecky, LR; Hartung, T; Türkmen, S; Graf, A; Krebs, S; Blum, H; Müller-Tidow, C; Thiede, C; Ehninger, G; Serve, H; Hecht, J; Berdel, WE; Greif, PA; Röllig, C; Baldus, CD
Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape.
Leukemia. 2017; 31(7): 1640-1644.
Doi: 10.1038/leu.2017.109
Web of Science
PubMed
FullText
FullText_MUG
2016
Originalarbeit (Zeitschrift)
** Dutta, S; Krause, A; Vosberg, S; Herold, T; Ksienzyk, B; Quintanilla-Martinez, L; Tizazu, B; Chopra, M; Graf, A; Krebs, S; Blum, H; Greif, PA; Vetter, A; Metzeler, K; Rothenberg-Thurley, M; Schneider, MR; Dahlhoff, M; Spiekermann, K; Zimber-Strobl, U; Wolf, E; Bohlander, SK
The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.
Leukemia. 2016; 30(5): 1166-1176.
Doi: 10.1038/leu.2015.349
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Hartmann, L; Dutta, S; Opatz, S; Vosberg, S; Reiter, K; Leubolt, G; Metzeler, KH; Herold, T; Bamopoulos, SA; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Hopfner, KP; Graf, A; Krebs, S; Blum, H; Middeke, JM; Stölzel, F; Thiede, C; Wolf, S; Bohlander, SK; Preiss, C; Chen-Wichmann, L; Wichmann, C; Sauerland, MC; Büchner, T; Berdel, WE; Wörmann, BJ; Braess, J; Hiddemann, W; Spiekermann, K; Greif, PA
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Nat Commun. 2016; 7(1): 11733-11733.
Doi: 10.1038/ncomms11733
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Vosberg, S; Herold, T; Hartmann, L; Neumann, M; Opatz, S; Metzeler, KH; Schneider, S; Graf, A; Krebs, S; Blum, H; Baldus, CD; Hiddemann, W; Spiekermann, K; Bohlander, SK; Mansmann, U; Greif, PA
Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia.
Genes Chromosomes Cancer. 2016; 55(7): 553-567.
Doi: 10.1002/gcc.22359
Web of Science
PubMed
FullText
FullText_MUG
2015
Originalarbeit (Zeitschrift)
** Neumann, M; Vosberg, S; Schlee, C; Heesch, S; Schwartz, S; Gökbuget, N; Hoelzer, D; Graf, A; Krebs, S; Bartram, I; Blum, H; Brüggemann, M; Hecht, J; Bohlander, SK; Greif, PA; Baldus, CD
Mutational spectrum of adult T-ALL.
Oncotarget. 2015; 6(5): 2754-2766.
Doi: 10.18632/oncotarget.2218
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Fallbericht
** Lübking, A; Vosberg, S; Konstandin, NP; Dufour, A; Graf, A; Krebs, S; Blum, H; Weber, A; Lenhoff, S; Ehinger, M; Spiekermann, K; Greif, PA; Cammenga, J
Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation.
Leuk Res Rep. 2015; 4(2): 72-75.
Doi: 10.1016/j.lrr.2015.10.001
(- Case Report)
[OPEN ACCESS]
PubMed
FullText
FullText_MUG
2014
Originalarbeit (Zeitschrift)
** Herold, T; Metzeler, KH; Vosberg, S; Hartmann, L; Röllig, C; Stölzel, F; Schneider, S; Hubmann, M; Zellmeier, E; Ksienzyk, B; Jurinovic, V; Pasalic, Z; Kakadia, PM; Dufour, A; Graf, A; Krebs, S; Blum, H; Sauerland, MC; Büchner, T; Berdel, WE; Woermann, BJ; Bornhäuser, M; Ehninger, G; Mansmann, U; Hiddemann, W; Bohlander, SK; Spiekermann, K; Greif, PA
Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis.
Blood. 2014; 124(8): 1304-1311.
Doi: 10.1182/blood-2013-12-540716
Web of Science
PubMed
FullText
FullText_MUG
Kurzbericht/Letter
** Neumann, M; Seehawer, M; Schlee, C; Vosberg, S; Heesch, S; von der Heide, EK; Graf, A; Krebs, S; Blum, H; Gökbuget, N; Schwartz, S; Hoelzer, D; Greif, PA; Baldus, CD
FAT1 expression and mutations in adult acute lymphoblastic leukemia.
Blood Cancer J. 2014; 4(5): e224-e224.
Doi: 10.1038/bcj.2014.44
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
2013
Originalarbeit (Zeitschrift)
** Neumann, M; Heesch, S; Schlee, C; Schwartz, S; Gökbuget, N; Hoelzer, D; Konstandin, NP; Ksienzyk, B; Vosberg, S; Graf, A; Krebs, S; Blum, H; Raff, T; Brüggemann, M; Hofmann, WK; Hecht, J; Bohlander, SK; Greif, PA; Baldus, CD
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations.
Blood. 2013; 121(23): 4749-4752.
Doi: 10.1182/blood-2012-11-465138
Web of Science
PubMed
FullText
FullText_MUG
** Opatz, S; Polzer, H; Herold, T; Konstandin, NP; Ksienzyk, B; Zellmeier, E; Vosberg, S; Graf, A; Krebs, S; Blum, H; Hopfner, KP; Kakadia, PM; Schneider, S; Dufour, A; Braess, J; Sauerland, MC; Berdel, WE; Büchner, T; Woermann, BJ; Hiddemann, W; Spiekermann, K; Bohlander, SK; Greif, PA
Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.
Blood. 2013; 122(10): 1761-1769.
Doi: 10.1182/blood-2013-01-476473
Web of Science
PubMed
FullText
FullText_MUG