** = Publikationen gelistet in SCI/SSCI/Pubmed
** Koschmieder, S; Isfort, S; Wolf, D; Heidel, FH; Hochhaus, A; Schafhausen, P; Griesshammer, M; Wolleschak, D; Platzbecker, U; Dohner, K; Jost, PJ; Parmentier, S; Schaich, M; von Bubnoff, N; Stegelmann, F; Maurer, A; Crysandt, M; Gezer, D; Kortmann, M; Franklin, J; Frank, J; Hellmich, M; Brummendorf, TH
Efficacy and safety of ruxolitinib in patients with newly-diagnosed polycythemia vera: futility analysis of the RuxoBEAT clinical trial of the GSG-MPN study group
ANN HEMATOL. 2023;
Doi: 10.1007/s00277-022-05080-7
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** Aftahy, AK; Barz, M; Lange, N; Baumgart, L; Thunstedt, C; Eller, MA; Wiestler, B; Bernhardt, D; Combs, SE; Jost, PJ; Delbridge, C; Liesche-Starnecker, F; Meyer, B; Gempt, J
The Impact of Postoperative Tumor Burden on Patients With Brain Metastases
FRONT ONCOL. 2022; 12: 869764
Doi: 10.3389/fonc.2022.869764
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** Balihodzic, A; Prinz, F; Dengler, MA; Calin, GA; Jost, PJ; Pichler, M
Non-coding RNAs and ferroptosis: potential implications for cancer therapy.
Cell Death Differ. 2022; 29(6):1094-1106
Doi: 10.1038/s41418-022-00998-x
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** Barth, DA; Stanzer, S; Spiegelberg, J; Bauernhofer, T; Absenger, G; Posch, F; Lipp, R; Halm, M; Szkandera, J; Balic, M; Gerger, A; Smolle, MA; Hutterer, GC; Klec, C; Jost, PJ; Kargl, J; Stradner, M; Pichler, M
Evaluation of autoantibodies as predictors of treatment response and immune-related adverse events during the treatment with immune checkpoint inhibitors: A prospective longitudinal pan-cancer study.
Cancer Med. 2022; 11(16):3074-3083
Doi: 10.1002/cam4.4675
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** Barth, DA; Stanzer, S; Spiegelberg, JA; Bauernhofer, T; Absenger, G; Szkandera, J; Gerger, A; Smolle, MA; Hutterer, GC; Ahyai, SA; Madl, T; Posch, F; Riedl, JM; Klec, C; Jost, PJ; Kargl, J; Stradner, MH; Pichler, M
Patterns of Peripheral Blood B-Cell Subtypes Are Associated With Treatment Response in Patients Treated With Immune Checkpoint Inhibitors: A Prospective Longitudinal Pan-Cancer Study.
Front Immunol. 2022; 13: 840207
Doi: 10.3389/fimmu.2022.840207
[OPEN ACCESS]
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** Baumgart, L; Barz, M; Delbridge, C; Aftahy, AK; Janssen, IK; Jost, PJ; Ryang, YM; Meyer, B; Gempt, J
Spinal Lesions as Clinical Manifestations of Plasma Cell Neoplasia
CURR ONCOL. 2022; 29(9): 6236-6244.
Doi: 10.3390/curroncol29090490
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** Dill, V; Wagner, CV; Keller, EC; Fernandez-Hernandez, FJ; Shoumariyeh, K; Odinius, TO; Buschhorn, L; Hauch, RT; Suren, C; Hecker, JS; Herhaus, P; Sandherr, M; Schmidt, B; Slotta-Huspenina, J; Bassermann, F; Höckendorf, U; Jilg, S; Branca, C; Vosberg, S; Jost, PJ
Elevated RIPK3 correlates with disease burden in myelofibrosis.
Blood Adv. 2022;
Doi: 10.1182/bloodadvances.2021006838
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** Fluhrer, H; Hutterer, GC; Golbeck, S; Stidl, M; Niedrist, T; Pichler, R; Mischinger, J; Seles, M; Mannweiler, S; Spiegelberg, J; Bauernhofer, T; Jost, PJ; Ahyai, S; Zigeuner, R; Pichler, M; Barth, DA
Improved overall survival of metastatic renal cell carcinoma patients in the era of modern tyrosine kinase inhibitors and immune checkpoint inhibitors: results from a real-life, population-based Austrian study comprising three decades of follow-up.
Ther Adv Med Oncol. 2022; 14: 17588359221134065
Doi: 10.1177/17588359221134065
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** Heilig, CE; Lassmann, A; Mughal, SS; Mock, A; Pirmann, S; Teleanu, V; Renner, M; Andresen, C; Kohler, BC; Aybey, B; Bauer, S; Siveke, JT; Hamacher, R; Folprecht, G; Richter, S; Schrock, E; Brandts, CH; Ahrens, M; Hohenberger, P; Egerer, G; Kindler, T; Boerries, M; Illert, AL; von Bubnoff, N; Apostolidis, L; Jost, PJ; Westphalen, CB; Weichert, W; Keilholz, U; Klauschen, F; Beck, K; Winter, U; Richter, D; Mohrmann, L; Bitzer, M; Schulze-Osthoff, K; Brors, B; Mechtersheimer, G; Kreutzfeldt, S; Heining, C; Lipka, DB; Stenzinger, A; Schlenk, RF; Horak, P; Glimm, H; Hubschmann, D; Frohling, S
Gene expression-based prediction of pazopanib efficacy in sarcoma
EUR J CANCER. 2022; 172: 107-118.
Doi: 10.1016/j.ejca.2022.05.025
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** Jahn, A; Rump, A; Widmann, TJ; Heining, C; Horak, P; Hutter, B; Paramasivam, N; Uhrig, S; Gieldon, L; Drukewitz, S; Kubler, A; Bermudez, M; Hackmann, K; Porrmann, J; Wagner, J; Arlt, M; Franke, M; Fischer, J; Kowalzyk, Z; William, D; Weth, V; Oster, S; Frohlich, M; Hullein, J; Gonzalez, CV; Kreutzfeldt, S; Mock, A; Heilig, CE; Lipka, DB; Mohrmann, L; Hanf, D; Oles, M; Teleanu, V; Allgauer, M; Ruhnke, L; Kutz, O; Knurr, A; Lassmann, A; Endris, V; Neumann, O; Penzel, R; Beck, K; Richter, D; Winter, U; Wolf, S; Pfutze, K; Georg, C; Meissburger, B; Buchhalter, I; Augustin, M; Aulitzky, WE; Hohenberger, P; Kroiss, M; Schirmacher, P; Schlenk, RF; Keilholz, U; Klauschen, F; Folprecht, G; Bauer, S; Siveke, JT; Brandts, CH; Kindler, T; Boerries, M; Illert, AL; von Bubnoff, N; Jost, PJ; Metzeler, KH; Bitzer, M; Schulze-Osthoff, K; von Kalle, C; Brors, B; Stenzinger, A; Weichert, W; Hubschmann, D; Frohling, S; Glimm, H; Schrock, E; Klink, B
Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers
ANN ONCOL. 2022; 33(11): 1186-1199.
Doi: 10.1016/j.annonc.2022.07.008
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** Jahn, SW; Jost, PJ
Challenges in integrating molecular profiles into clinical cancer care
MEMO-MAG EUR MED ONC. 2022;
Doi: 10.1007/s12254-022-00838-1
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** Maisel, F; Smolle, MA; Mollnar, S; Riedl, JM; Barth, DA; Seles, M; Terbuch, A; Rossmann, CH; Eisner, F; Mannweiler, S; Hutterer, G; Zigeuner, R; Pummer, K; Smolle-Jüttner, FM; Lindenmann, J; Stotz, M; Gerger, A; Jost, PJ; Bauernhofer, T; Pichler, M; Posch, F
Benefit of Metastasectomy in Renal Cell Carcinoma: A Propensity Score Analysis.
Clin Genitourin Cancer. 2022; 20(4):344-353
Doi: 10.1016/j.clgc.2022.03.010
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** Meinhardt, AL; Munkhbaatar, E; Höckendorf, U; Dietzen, M; Dechant, M; Anton, M; Jacob, A; Steiger, K; Weichert, W; Brcic, L; McGranahan, N; Branca, C; Kaufmann, T; Dengler, MA; Jost, PJ
The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner.
Oncogene. 2022; 41(9):1376-1382
Doi: 10.1038/s41388-021-02161-1
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** Posch, F; Niedrist, T; Glantschnig, T; Firla, S; Moik, F; Kolesnik, E; Wallner, M; Verheyen, N; Jost, PJ; Zirlik, A; Pichler, M; Balic, M; Rainer, PP
Left ventricular ejection fraction and cardiac biomarkers for dynamic prediction of cardiotoxicity in early breast cancer.
Front Cardiovasc Med. 2022; 9: 933428
Doi: 10.3389/fcvm.2022.933428
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** Reissig, TM; Uhrig, S; Jost, PJ; Luchini, C; Vicentini, C; Liffers, ST; Allgauer, M; Adsay, V; Scarpa, A; Lawlor, RT; Frohling, S; Stenzinger, A; Kloppel, G; Schildhaus, HU; Siveke, JT
MCL1 as putative target in pancreatoblastoma
VIRCHOWS ARCH. 2022;
Doi: 10.1007/s00428-022-03349-w
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** Riedl, JM; Schwarzenbacher, E; Moik, F; Horvath, L; Gantschnigg, A; Renneberg, F; Posch, F; Barth, DA; Stotz, M; Pichler, M; Hatzl, S; Fandler-Höfler, S; Gressenberger, P; Gary, T; Jost, PJ; Greil, R; Ay, C; Djanani, A; Gerger, A; Schlick, K
Patterns of Thromboembolism in Patients with Advanced Pancreatic Cancer Undergoing First-Line Chemotherapy with FOLFIRINOX or Gemcitabine/nab-Paclitaxel.
Thromb Haemost. 2022; 122(4):633-645
Doi: 10.1055/a-1548-4847
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** Suppan, C; Graf, R; Jahn, S; Zhou, Q; Klocker, EV; Bartsch, R; Terbuch, A; Kashofer, K; Regitnig, P; Lindenmann, J; Posch, F; Gerritsmann, H; Jost, PJ; Heitzer, E; Dandachi, N; Balic, M
Sensitive and robust liquid biopsy-based detection of PIK3CA mutations in hormone-receptor-positive metastatic breast cancer patients.
Br J Cancer. 2022; 126(3):456-463
Doi: 10.1038/s41416-021-01601-9
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** Terbuch, A; Posch, F; Bauernhofer, T; Jost, PJ; Partl, R; Stranzl-Lawatsch, H; Baciarello, G; Fizazi, K; Giannatempo, P; Verzoni, E; Sweeney, C; Ravi, P; Tran, B; Basso, U; White, J; Vincenzi, B; Oing, C; Cutuli, HJ; Dieckmann, KP; Gamulin, M; Chovanec, M; Fankhauser, CD; Heidenreich, A; Mohamad, O; Thibault, C; Fischer, S; Gillessen, S, , International, Germ, Cell, Cancer, Collaborative, Group
Patterns of Disease Progression and Outcome of Patients With Testicular Seminoma Who Relapse After Adjuvant or Curative Radiation Therapy.
Int J Radiat Oncol Biol Phys. 2022; 113(4):825-832
Doi: 10.1016/j.ijrobp.2022.03.021
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** Wahida, A; Buschhorn, L; Frohling, S; Jost, PJ; Schneeweiss, A; Lichter, P; Kurzrock, R
The coming decade in precision oncology: six riddles
NAT REV CANCER. 2022;
Doi: 10.1038/s41568-022-00529-3
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** Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; McGranahan, N; Jost, P
Inflammatory cell death acts as tumor suppressor in lung adenocarcinoma
INTERNIST. 2022; 63(SUPPL 3):338-339.
[Oral Communication]
Web of Science
** Brcic, L; Zacharias, M; Konjic, S; Kashofer, K; Absenger, G; Jost, PJ; Wurm, R; Lindenmann, J; Terbuch, A
Molecular testing in lung squamous cell carcinoma using DNA- and RNA-based next-generation sequencing: A singlecenter experience
ANN ONCOL. 2022; 38(9): S1557-S1557.
Doi: 10.1016/j.annonc.2022.10.344
[Poster]
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** Keller, EC; Jost, PJ; Schwamborn, K; Weichert, W; Horn, T; Slotta-Huspenina, J
Mixed Lineage Kinase Domain-like Protein (MLKL) in Primary Resected Bladder Cancer: Expression, Prognostic Role and Correlations with the Immune Environment
MODERN PATHOL. 2022; 35(SUPPL 2): 613-613.
[Poster]
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** Keller, EC; Jost, PJ; Schwamborn, K; Weichert, W; Horn, T; Slotta-Huspenina, J
Mixed Lineage Kinase Domain-like Protein (MLKL) in Primary Resected Bladder Cancer: Expression, Prognostic Role and Correlations with the Immune Environment
LAB INVEST. 2022; 102(SUPPL 1): 613-613.
[Poster]
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** Moik, F; Riedl, J; Barth, D; Chan, WSE; Wiedemann, S; Holler, C; Fuereder, T; Jost, P; Pabinger, I; Preusser, M; Ay, C
Early Dynamics of C-Reactive Protein Predict Risk of Venous Thromboembolism in Patients with Cancer Treated with Immune Checkpoint Inhibitors
BLOOD. 2022; 140: 1250-1251.
Doi: 10.1182/blood-2022-160087
[Oral Communication]
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** Riedl, JM; Barth, D; Steinlechner, S; Moik, F; Posch, F; Schlintl, V; Mayer, MC; Sandner, AM; Berton, F; Koch, L; John, N; Wurm, R; Pichler, M; Absenger, G; Jost, PJ; Wohlkonig, C; Richtig, E; Winder, T; Gerger, A; Terbuch, A
Early CRP Kinetics after Initiation of Immune Checkpoint Inhibitors is a predictive Biomarker for Treatment Response independent of the Tumor Antity
ONCOL RES TREAT. 2022; 45(SUPPL 2):228-228.-Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie; Okt 7-10, 2022; Wien.
[Poster]
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** Schranz, A; Sternad, C; Mischinger, HJ; Wagner, D; Jost, PJ; Riedl, J; Wolfler, A; Pieber, T; Sourij, H; Aberer, F
Incidence of diabetes and its impact on survival after pancreatic tumor surgery - a retrospective data analysis
WIEN KLIN WOCHENSCHR. 2022; 134(SUPPL 4):258-259.-Jahrestagung der Österreichischen Diabetesgesellschaft ;
[Poster]
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** Zacharias, M; Konjic, S; Absenger, G; Hochmair, MJ; Fabikan, H; Weinlinger, C; Illini, O; Jost, PJ; Schlintl, V; Wurm, R; Lindenmann, J; Fediuk, M; Brcic, L; Terbuch, A
Clinicopathological Features of Rare but Targetable Mutations in Surgically Resected Lung Carcinomas
J THORAC ONCOL. 2022; 17(9): S201-S202.
[Poster]
Web of Science
Barth, D; Stradner, M; Hutterer, H; Spiegelberg, J; Bauernhofer, T; Absenger, G; Jost, P; Pichler, M
Blood-based B-cell subtypes as predictors of treatment response during treatment with immune checkpoint inhibitors: a prospective longitudinal pan-cancer study.
Proceedings of the Annual Meeting of the Austrian Society of Haematology and Medical Oncology 2022. 2022; -OeGHO Frühjahrstagung 2022; APR 8-10, 2022; Graz, AUSTRIA.
[Poster]
Huemer, M; Jahn-Kuch D; Hofmann, G; Andritsch, E; Farkas C; Schaupp, W; Masel EK; Jost JP; Pichler M
Trends of public interest in palliative care, euthanasia, and advanced health care directives in Austria, Germany, and Switzerland using big data from Google
Proceedings of the Annual Meeting of the Austrian Society of Haematology and Medical Oncology. 2022; 22(3):17-17.-OeGHO & AHOP Frühjahrstagung; APR 8-10, 2022; Graz, AUSTRIA.
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Krajina, K; Kapeller, A; Dengler, M; Jost, P; Pichler, M; Klec, C
The long non-coding RNA NORAD and its relevance on PARP inhibitor sensitivity in triple negative breast cancer
Proceedings of the Annual Meeting of the Austrian Society
of Haematology and Medical Oncology. 2022; -OeGHO- & AHOP-Frühjahrstagung 2022; APR 8-10, 2022; Graz, AUSTRIA.
[Poster]
Lindenmann, J; Fink-Neuboeck, N; Fediuk, M; Porubsky, Ch; Absenger, G; Mykoliuk, I; Brcic, L; Anegg, U; Maier, A; Jost, P; Smolle, J; Smolle-Juettner, FM
Recurrence and survival following surgery of T3 esophageal carcinoma with curative intent. Role of circumferential resection margin.
European Surgrey- ACA. 2022; 54: 50-50.-63. Österreichischer Chirurgenkongress; JUN 15-17, 2022; Graz, AUSTRIA.
[Oral Communication]
** Barz, M; Aftahy, K; Janssen, I; Ryang, YM; Prokop, G; Combs, SE; Jost, PJ; Meyer, B; Gempt, J
Spinal Manifestation of Malignant Primary (PLB) and Secondary Bone Lymphoma (SLB).
CURR ONCOL. 2021; 28(5): 3891-3899.
Doi: 10.3390/curroncol28050332
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** Carlet, M; Völse, K; Vergalli, J; Becker, M; Herold, T; Arner, A; Senft, D; Jurinovic, V; Liu, WH; Gao, Y; Dill, V; Fehse, B; Baldus, CD; Bastian, L; Lenk, L; Schewe, DM; Bagnoli, JW; Vick, B; Schmid, JP; Wilhelm, A; Marschalek, R; Jost, PJ; Miething, C; Riecken, K; Schmidt-Supprian, M; Binder, V; Jeremias, I
In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets.
Nat Commun. 2021; 12(1): 5655
Doi: 10.1038/s41467-021-25963-z
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** Horak, P; Heining, C; Kreutzfeldt, S; Hutter, B; Mock, A; Hüllein, J; Fröhlich, M; Uhrig, S; Jahn, A; Rump, A; Gieldon, L; Möhrmann, L; Hanf, D; Teleanu, V; Heilig, CE; Lipka, DB; Allgäuer, M; Ruhnke, L; Laßmann, A; Endris, V; Neumann, O; Penzel, R; Beck, K; Richter, D; Winter, U; Wolf, S; Pfütze, K; Geörg, C; Meißburger, B; Buchhalter, I; Augustin, M; Aulitzky, WE; Hohenberger, P; Kroiss, M; Schirmacher, P; Schlenk, RF; Keilholz, U; Klauschen, F; Folprecht, G; Bauer, S; Siveke, JT; Brandts, CH; Kindler, T; Boerries, M; Illert, AL; von, Bubnoff, N; Jost, PJ; Spiekermann, K; Bitzer, M; Schulze-Osthoff, K; von, Kalle, C; Klink, B; Brors, B; Stenzinger, A; Schröck, E; Hübschmann, D; Weichert, W; Glimm, H; Fröhling, S
Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers.
Cancer Discov. 2021; 11(11): 2780-2795.
Doi: 10.1158/2159-8290.CD-21-0126
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** Huemer, M; Jahn-Kuch, D; Hofmann, G; Andritsch, E; Farkas, C; Schaupp, W; Masel, EK; Jost, PJ; Pichler, M
Trends and Patterns in the Public Awareness of Palliative Care, Euthanasia, and End-of-Life Decisions in 3 Central European Countries Using Big Data Analysis From Google: Retrospective Analysis.
J Med Internet Res. 2021; 23(9): e28635
Doi: 10.2196/28635
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** Kricheldorf, K; Döhner, K; Stegelmann, F; Jost, PJ; Lang, F; Radsak, M; Hansen, R; Heuer, V; Röhrig, R; Brümmendorf, TH; Koschmieder, S; Isfort, S
Challenges of patients with myeloproliferative neoplasms (MPN) in times of COVID: First results from a patient survey by the German Study Group for MPN.
LEUKEMIA RES. 2021; 110: 106646
Doi: 10.1016/j.leukres.2021.106646
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** Liotta, L; Lange, S; Maurer, HC; Olive, KP; Braren, R; Pfarr, N; Burger, S; Muckenhuber, A; Jesinghaus, M; Steiger, K; Weichert, W; Friess, H; Schmid, R; Algül, H; Jost, PJ; Ramser, J; Fischer, C; Quante, AS; Reichert, M; Quante, M
PALLD mutation in a European family conveys a stromal predisposition for familial pancreatic cancer.
JCI Insight. 2021; 6(8):
Doi: 10.1172/jci.insight.141532
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** Müller, M; Posch, F; Kiem, D; Barth, D; Horvath, L; Stotz, M; Schaberl-Moser, R; Pichler, M; Greil, R; Jost, PJ; Seeber, A; Amann, A; Schlick, K; Gerger, A; Riedl, JM
Benefit of second-line therapy for advanced esophageal squamous cell carcinoma: a tri-center propensity score analysis.
Ther Adv Med Oncol. 2021; 13: 17588359211039930
Doi: 10.1177/17588359211039930
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** Odinius, TO; Buschhorn, L; Wagner, C; Hauch, RT; Dill, V; Dechant, M; Buck, MC; Shoumariyeh, K; Moog, P; Schwaab, J; Reiter, A; Brockow, K; Götze, K; Bassermann, F; Höckendorf, U; Branca, C; Jost, PJ; Jilg, S
Comprehensive characterization of central BCL-2 family members in aberrant eosinophils and their impact on therapeutic strategies.
J CANCER RES CLIN. 2021;
Doi: 10.1007/s00432-021-03827-9
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** Pichler, T; Rohrmoser, A; Letsch, A; Westphalen, CB; Keilholz, U; Heinemann, V; Lamping, M; Jost, PJ; Riedmann, K; Herschbach, P; Goerling, U
Information, communication, and cancer patients' trust in the physician: what challenges do we have to face in an era of precision cancer medicine?
Support Care Cancer. 2021; 29(4):2171-2178
Doi: 10.1007/s00520-020-05692-7
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** Smolle, E; Taucher, V; Lindenmann, J; Jost, PJ; Pichler, M
Current Knowledge about Mechanisms of Drug Resistance against ALK Inhibitors in Non-Small Cell Lung Cancer.
Cancers (Basel). 2021; 13(4):
Doi: 10.3390/cancers13040699
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** Suppan, C; Posch, F; Mueller, HD; Mischitz, N; Steiner, D; Klocker, EV; Setaffy, L; Bargfrieder, U; Hammer, R; Hauser, H; Jost, PJ; Dandachi, N; Lax, S; Balic, M
Patterns of Recurrence after Neoadjuvant Therapy in Early Breast Cancer, according to the Residual Cancer Burden Index and Reductions in Neoadjuvant Treatment Intensity.
Cancers (Basel). 2021; 13(10):
Doi: 10.3390/cancers13102492
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** Wahida, A; Müller, M; Hiergeist, A; Popper, B; Steiger, K; Branca, C; Tschurtschenthaler, M; Engleitner, T; Donakonda, S; De, Coninck, J; Öllinger, R; Pfautsch, MK; Müller, N; Silva, M; Usluer, S; Oberg, ET; Böttcher, JP; Pfarr, N; Anton, M; Slotta-Huspenina, JB; Nerlich, AG; Madl, T; Basic, M; Bleich, A; Berx, G; Ruland, J; Knolle, PA; Rad, R; Adolph, TE; Vandenabeele, P; Kanegane, H; Gessner, A; Jost, PJ; Yabal, M
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells.
Sci Immunol. 2021; 6(65): eabf7235
Doi: 10.1126/sciimmunol.abf7235
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** Wang, X; Ros, U; Agrawal, D; Keller, EC; Slotta-Huspenina, J; Dill, V; Shen, B; Shi, R; Herold, T; Belka, C; Mishra, R; Bassermann, F; Garcia-Saez, AJ; Jost, PJ
Correction: MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF.
Cell Death Differ. 2021;
Doi: 10.1038/s41418-021-00826-8
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** Wang, X; Ros, U; Agrawal, D; Keller, EC; Slotta-Huspenina, J; Dill, V; Shen, B; Shi, R; Herold, T; Belka, C; Mishra, R; Bassermann, F; Garcia-Saez, AJ; Jost, PJ
MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF.
CELL DEATH DIFFER. 2021;
Doi: 10.1038/s41418-021-00811-1
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** Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; Branca, C; McGranahan, N; Jost, PJ
RIPK3 downregulation in lung cancer alters the tumor immune micro-environment supporting tumor progression
ONCOL RES TREAT. 2021; 44: 51-52.
Web of Science
** Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; McGranahan, N; Jost, PJ
Necroptosis establishes an inflammatory tumor immune microenvironment acting as tumor suppressor in lung adenocarcinoma
ANN ONCOL. 2021; 32: S945-S945.
Doi: 10.1016/j.annonc.2021.08.1788
[Poster]
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** Dill, V; Wagner, C; Keller, E; Shoumariyeh, K; Odinius, T; Buschhorn, L; Suren, C; Hecker, J; Herhaus, P; Sandherr, M; Schmidt, B; Slotta-Huspenina, J; Bassermann, F; Hockendorf, U; Branca, C; Jilg, S; Jost, PJ
RIPK3-dependent necroinflammation as a disease promoting mechanism in human myelofibrosis
ONCOL RES TREAT. 2021; 44: 161-161.
Web of Science
** Jost, PJ; Munkhbaatar, E; Dietzen, M; Branca, C; McGranahan, N
Clonal evolution in lung cancer highlights MCL-1 gains as therapeutic target in lung adenocarcinoma
J THORAC ONCOL. 2021; 16(4):S704-S704.
[Poster]
Web of Science
** Lorch, M; Pfirrmann, M; Fabisch, C; Oberle, L; Kohn, D; Kohlbrenner, K; Brummendorf, TH; Burchert, A; Krause, SW; le Coutre, P; Hanel, M; Franke, GN; Stegelmann, F; Radsak, M; Kunzmann, V; Jost, PJ; Hofmann, WK; Hochhaus, A; Saussele, S
Health-related quality of life (HRQoL) in CML-patients at diagnosis compared to general population
ONCOL RES TREAT. 2021; 44: 71-72.
Web of Science
** Terbuch, A; Absenger, G; Steinlechner, S; Jost, P; Wurm, R; Wohlkonig, C; Olschewski, H; Richtig, E; Koch, L; Winder, T; Woll, E; Gerger, A
Autriche - AUsTrian Registry for Immune CHEckpoint inhibitors
ONCOL RES TREAT. 2021; 44: 229-229.
[Poster]
Web of Science
Klocker, EV; Posch, F; Suppan, C; Mischitz, N; Dengler, L; Steiner, D; Müller, HD; Jost, P; Dandachi, N; Balic, M
Histopathological features and prognosis of early lobular breast cancer
Oncology Research and Treatment, Vol. 44, Suppl. 2, 2021. 2021; -Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie ; OCT 1-4, 2021; Berlin, GERMANY.
[Poster]
Smolle, M; Woelfel, J; Acem, I; Van De Sande, MAJ; Jeys, L; Bonekamp, H; Pollock, R; Keller, J; Tunn, PU; Haas, R; Van Ginkel, RJ; Verhoef, C; Posch, F; Liegl-Atzwanger, B; Moustafa-Hubmer, D; Jost, PJ; Leithner, A; Szkandera J
Neoadjuvant and adjuvant radiotherapy decreases the risk of local recurrence and adjuvant chemotherapy improves overall survival in a multicentre cohort of 2184 extremity soft tissue sarcoma patients
CTOS Abstract Book. 2021; -CTOS (Connective Tissue Oncology Society); NOV 10-13; Toronto, CANADA.
[Oral Communication]
Smolle, MA; Woelfel, J; Acem, I; van de Sande, M; Jeys, L; Bonekamp, H; Pollock, R; Keller, J; Tunn, PU; Haas, R; van Ginkel, RJ; Verhoef, C; Posch, F; Liegl-Atzwanger, B; Moustafa-Hubmer, D; Jost, P; Leithner, A; Szkandera, J
Effect of Neoadjuvant and Adjuvant Radiotherapy on Local Recurrence, Distant Metastasis, and Overall Survival in Extremity Soft Tissue Sarcoma.
Abstract Book of the EMSOS 2021. 2021; -EMSOS Annual Meeting 2021; DEC 1-3, 2021; Graz, AUSTRIA.
[Onlinepräsentation]
** Crodel, CC; Jentsch-Ullrich, K; Koschmieder, S; Kämpfe, D; Griesshammer, M; Döhner, K; Jost, PJ; Wolleschak, D; Isfort, S; Stegelmann, F; Jilg, S; Hofmann, V; Auteri, G; Rachow, T; Ernst, P; Brioli, A; von Lilienfeld-Toal, M; Hochhaus, A; Palandri, F; Heidel, FH
Frequency of infections in 948 MPN patients: a prospective multicenter patient-reported pilot study.
Leukemia. 2020; 34(7):1949-1953
Doi: 10.1038/s41375-020-0890-1
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** Crodel, CC; Jentsch-Ullrich, K; Koschmieder, S; Kämpfe, D; Griesshammer, M; Döhner, K; Jost, PJ; Wolleschak, D; Isfort, S; Stegelmann, F; Jilg, S; Hofmann, V; Auteri, G; Rachow, T; Ernst, P; Brioli, A; von Lilienfeld-Toal, M; Hochhaus, A; Palandri, F; Heidel, FH
Correction: Frequency of infections in 948 MPN patients: a prospective multicenter patient-reported pilot study.
Leukemia. 2020; 34(11): 3106-3106.
Doi: 10.1038/s41375-020-0970-2
[OPEN ACCESS]
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** Dill, V; Kauschinger, J; Hauch, RT; Buschhorn, L; Odinius, TO; Müller-Thomas, C; Mishra, R; Kyncl, MC; Schmidt, B; Prodinger, PM; Hempel, D; Bellos, F; Höllein, A; Kern, W; Haferlach, T; Slotta-Huspenina, J; Bassermann, F; Peschel, C; Götze, KS; Waizenegger, IC; Höckendorf, U; Jost, PJ; Jilg, S
Inhibition of PLK1 by capped-dose volasertib exerts substantial efficacy in MDS and sAML while sparing healthy haematopoiesis.
Eur J Haematol. 2020; 104(2):125-137
Doi: 10.1111/ejh.13354
[OPEN ACCESS]
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** Hähnel, T; Baldow, C; Guilhot, J; Guilhot, F; Saussele, S; Mustjoki, S; Jilg, S; Jost, PJ; Dulucq, S; Mahon, FX; Roeder, I; Fassoni, AC; Glauche, I
Model-Based Inference and Classification of Immunologic Control Mechanisms from TKI Cessation and Dose Reduction in Patients with CML.
Cancer Res. 2020; 80(11):2394-2406
Doi: 10.1158/0008-5472.CAN-19-2175
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** Jayavelu, AK; Schnöder, TM; Perner, F; Herzog, C; Meiler, A; Krishnamoorthy, G; Huber, N; Mohr, J; Edelmann-Stephan, B; Austin, R; Brandt, S; Palandri, F; Schröder, N; Isermann, B; Edlich, F; Sinha, AU; Ungelenk, M; Hübner, CA; Zeiser, R; Rahmig, S; Waskow, C; Coldham, I; Ernst, T; Hochhaus, A; Jilg, S; Jost, PJ; Mullally, A; Bullinger, L; Mertens, PR; Lane, SW; Mann, M; Heidel, FH
Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Nature. 2020; 588(7836):157-163
Doi: 10.1038/s41586-020-2968-3
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** Joensuu, H; Eriksson, M; Sundby Hall, K; Reichardt, A; Hermes, B; Schütte, J; Cameron, S; Hohenberger, P; Jost, PJ; Al-Batran, SE; Lindner, LH; Bauer, S; Wardelmann, E; Nilsson, B; Kallio, R; Jaakkola, P; Junnila, J; Alvegård, T; Reichardt, P
Survival Outcomes Associated With 3 Years vs 1 Year of Adjuvant Imatinib for Patients With High-Risk Gastrointestinal Stromal Tumors: An Analysis of a Randomized Clinical Trial After 10-Year Follow-up.
JAMA Oncol. 2020; 6(8):1241-1246
Doi: 10.1001/jamaoncol.2020.2091
[OPEN ACCESS]
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** Jost, PJ; Vucic, D
Regulation of Cell Death and Immunity by XIAP.
JACC-CARDIOVASC INTE. 2020; 13(15): a036426
Doi: 10.1101/cshperspect.a036426
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** Jost, PJ; Vucic, D
Regulation of Cell Death and Immunity by XIAP.
Cold Spring Harb Perspect Biol. 2020; 12(8):
Doi: 10.1101/cshperspect.a036426
[OPEN ACCESS]
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** Knop, J; Spilgies, LM; Rufli, S; Reinhart, R; Vasilikos, L; Yabal, M; Owsley, E; Jost, PJ; Marsh, RA; Wajant, H; Robinson, MD; Kaufmann, T; Wong, WW
Correction: TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP.
Cell Death Dis. 2020; 11(1):56-56
Doi: 10.1038/s41419-020-2261-2
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** Lampl, S; Janas, MK; Donakonda, S; Brugger, M; Lohr, K; Schneider, A; Manske, K; Sperl, LE; Kläger, S; Küster, B; Wettmarshausen, J; Müller, C; Laschinger, M; Hartmann, D; Hüser, N; Perocchi, F; Schmitt-Kopplin, P; Hagn, F; Zender, L; Hornung, V; Borner, C; Pichlmair, A; Kashkar, H; Klingenspor, M; Prinz, M; Schreiner, S; Conrad, M; Jost, PJ; Zischka, H; Steiger, K; Krönke, M; Zehn, D; Protzer, U; Heikenwälder, M; Knolle, PA; Wohlleber, D
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
J Hepatol. 2020; 73(6):1347-1359
Doi: 10.1016/j.jhep.2020.06.026
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** Munkhbaatar, E; Dietzen, M; Agrawal, D; Anton, M; Jesinghaus, M; Boxberg, M; Pfarr, N; Bidola, P; Uhrig, S; Höckendorf, U; Meinhardt, AL; Wahida, A; Heid, I; Braren, R; Mishra, R; Warth, A; Muley, T; Poh, PSP; Wang, X; Fröhling, S; Steiger, K; Slotta-Huspenina, J; van, Griensven, M; Pfeiffer, F; Lange, S; Rad, R; Spella, M; Stathopoulos, GT; Ruland, J; Bassermann, F; Weichert, W; Strasser, A; Branca, C; Heikenwalder, M; Swanton, C; McGranahan, N; Jost, PJ
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.
Nat Commun. 2020; 11(1):4527
Doi: 10.1038/s41467-020-18372-1
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** Safi, S; Yamauchi, Y; Hoffmann, H; Weichert, W; Jost, PJ; Winter, H; Muley, T; Beckhove, P
Circulating Interleukin-4 Is Associated with a Systemic T Cell Response against Tumor-Associated Antigens in Treatment-Naïve Patients with Resectable Non-Small-Cell Lung Cancer.
Cancers (Basel). 2020; 12(12):
Doi: 10.3390/cancers12123496
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** Scherr, AL; Mock, A; Gdynia, G; Schmitt, N; Heilig, CE; Korell, F; Rhadakrishnan, P; Hoffmeister, P; Metzeler, KH; Schulze-Osthoff, K; Illert, AL; Boerries, M; Trojan, J; Waidmann, O; Falkenhorst, J; Siveke, J; Jost, PJ; Bitzer, M; Malek, NP; Vecchione, L; Jelas, I; Brors, B; Glimm, H; Stenzinger, A; Grekova, SP; Gehrig, T; Schulze-Bergkamen, H; Jäger, D; Schirmacher, P; Heikenwalder, M; Goeppert, B; Schneider, M; Fröhling, S; Köhler, BC
Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer.
Cell Death Dis. 2020; 11(10):875
Doi: 10.1038/s41419-020-03092-7
[OPEN ACCESS]
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** Schwaab, J; Naumann, N; Luebke, J; Jawhar, M; Somervaille, TCP; Williams, MS; Frewin, R; Jost, PJ; Lichtenegger, FS; La Rosée, P; Storch, N; Haferlach, T; Horny, HP; Fabarius, A; Haferlach, C; Burchert, A; Hofmann, WK; Cross, NCP; Hochhaus, A; Reiter, A; Metzgeroth, G
Response to tyrosine kinase inhibitors in myeloid neoplasms associated with PCM1-JAK2, BCR-JAK2 and ETV6-ABL1 fusion genes.
Am J Hematol. 2020; 95(7):824-833
Doi: 10.1002/ajh.25825
[OPEN ACCESS]
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** Munkhbaatar, E; Dietzen, M; McGranahan, N; Jost, PJ
Dissecting clonal evolution in lung adenocarcinoma identified chromosomal gains on 1q21 implying novel therapeutic targets.
ONCOL RES TREAT. 2020; 43(SUPPL 4):135-135.
[Onlinepräsentation]
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** Bidola, P; Martins de Souza E Silva, J; Achterhold, K; Munkhbaatar, E; Jost, PJ; Meinhardt, AL; Taphorn, K; Zdora, MC; Pfeiffer, F; Herzen, J
A step towards valid detection and quantification of lung cancer volume in experimental mice with contrast agent-based X-ray microtomography.
Sci Rep. 2019; 9(1):1325-1325
Doi: 10.1038/s41598-018-37394-w
[OPEN ACCESS]
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** Huemer, F; Melchardt, T; Jansko, B; Wahida, A; Jilg, S; Jost, PJ; Klieser, E; Steiger, K; Magnes, T; Pleyer, L; Greil-Ressler, S; Rass, C; Greil, R; Egle, A
Durable remissions with venetoclax monotherapy in secondary AML refractory to hypomethylating agents and high expression of BCL-2 and/or BIM.
Eur J Haematol. 2019; 102(5):437-441
Doi: 10.1111/ejh.13218
(- Case Report)
[OPEN ACCESS]
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** Jilg, S; Hauch, RT; Kauschinger, J; Buschhorn, L; Odinius, TO; Dill, V; Müller-Thomas, C; Herold, T; Prodinger, PM; Schmidt, B; Hempel, D; Bassermann, F; Peschel, C; Götze, KS; Höckendorf, U; Haferlach, T; Jost, PJ
Venetoclax with azacitidine targets refractory MDS but spares healthy hematopoiesis at tailored dose.
Exp Hematol Oncol. 2019; 8(10):9-9
Doi: 10.1186/s40164-019-0133-1
[OPEN ACCESS]
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** Jilg, S; Rassner, M; Maier, J; Waldeck, S; Kehl, V; Follo, M; Philipp, U; Sauter, A; Specht, K; Mitschke, J; Lange, T; Bauer, S; Jost, PJ; Peschel, C; Duyster, J; Gaiser, T; Hohenberger, P; von Bubnoff, N
Circulating cKIT and PDGFRA DNA indicates disease activity in Gastrointestinal Stromal Tumor (GIST).
Int J Cancer. 2019; 145(8):2292-2303
Doi: 10.1002/ijc.32282
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** Jost, PJ; Höckendorf, U
Necroinflammation emerges as a key regulator of hematopoiesis in health and disease.
Cell Death Differ. 2019; 26(1):53-67
Doi: 10.1038/s41418-018-0194-4
[OPEN ACCESS]
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** Knop, J; Spilgies, LM; Rufli, S; Reinhart, R; Vasilikos, L; Yabal, M; Owsley, E; Jost, PJ; Marsh, RA; Wajant, H; Robinson, MD; Kaufmann, T; Wong, WW
TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP.
Cell Death Dis. 2019; 10(10):700-700
Doi: 10.1038/s41419-019-1938-x
[OPEN ACCESS]
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** Müller, N; Fischer, JC; Yabal, M; Haas, T; Poeck, H; Jost, PJ
XIAP deficiency in hematopoietic recipient cells drives donor T-cell activation and GvHD in mice.
Eur J Immunol. 2019; 49(3):504-507
Doi: 10.1002/eji.201847818
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** Riedmann, K; Bassermann, F; Jost, PJ
[Kinase inhibitors in oncology : What is new?]
Internist (Berl). 2019; 60(5):540-544
Doi: 10.1007/s00108-019-0577-8
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** Horak, P; Heining, C; Kreutzfeldt, S; Heilig, CE; Mohrmann, L; Gieldon, L; Frohlich, M; Uhrig, S; Hubschmann, D; Beck, K; Richter, D; Wolf, S; Pfutze, K; Georg, C; Meissburger, B; Klauschen, F; Ochsenreither, S; Folprecht, G; Siveke, J; Bauer, S; Kindler, T; Brandts, C; Borries, M; von Bubnoff, N; Spiekermann, K; Jost, PJ; Schulze-Osthoff, K; Bitzer, M; Schirmacher, P; von Kalle, C; Schlenk, R; Klink, B; Flutter, B; Weichert, W; Stenzinger, A; Schrock, E; Brors, B; Glimm, H; Frohling, S
Clinical relevance of comprehensive genomic analysis in advanced-stage cancers and rare malignancies: Results from the MASTER trial of the German Cancer Consortium
CANCER RES. 2019; 79(13):
Doi: 10.1158/1538-7445.AM2019-468
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** Pfarr, N; Boxberg, M; Riedmann, K; Jesinghaus, M; Konukiewitz, B; Glimm, H; Jost, PJ; Frohling, S; Weichert, W
Detection of the mutation burden status and microsatellite instability by targeted next generation sequencing applying a large gene panel
VIRCHOWS ARCH. 2019; 475: S104-S104.
Web of Science
** Galluzzi, L; Vitale, I; Aaronson, SA; Abrams, JM; Adam, D; Agostinis, P; Alnemri, ES; Altucci, L; Amelio, I; Andrews, DW; Annicchiarico-Petruzzelli, M; Antonov, AV; Arama, E; Baehrecke, EH; Barlev, NA; Bazan, NG; Bernassola, F; Bertrand, MJM; Bianchi, K; Blagosklonny, MV; Blomgren, K; Borner, C; Boya, P; Brenner, C; Campanella, M; Candi, E; Carmona-Gutierrez, D; Cecconi, F; Chan, FK; Chandel, NS; Cheng, EH; Chipuk, JE; Cidlowski, JA; Ciechanover, A; Cohen, GM; Conrad, M; Cubillos-Ruiz, JR; Czabotar, PE; D'Angiolella, V; Dawson, TM; Dawson, VL; De Laurenzi, V; De Maria, R; Debatin, KM; DeBerardinis, RJ; Deshmukh, M; Di Daniele, N; Di Virgilio, F; Dixit, VM; Dixon, SJ; Duckett, CS; Dynlacht, BD; El-Deiry, WS; Elrod, JW; Fimia, GM; Fulda, S; García-Sáez, AJ; Garg, AD; Garrido, C; Gavathiotis, E; Golstein, P; Gottlieb, E; Green, DR; Greene, LA; Gronemeyer, H; Gross, A; Hajnoczky, G; Hardwick, JM; Harris, IS; Hengartner, MO; Hetz, C; Ichijo, H; Jäättelä, M; Joseph, B; Jost, PJ; Juin, PP; Kaiser, WJ; Karin, M; Kaufmann, T; Kepp, O; Kimchi, A; Kitsis, RN; Klionsky, DJ; Knight, RA; Kumar, S; Lee, SW; Lemasters, JJ; Levine, B; Linkermann, A; Lipton, SA; Lockshin, RA; López-Otín, C; Lowe, SW; Luedde, T; Lugli, E; MacFarlane, M; Madeo, F; Malewicz, M; Malorni, W; Manic, G; Marine, JC; Martin, SJ; Martinou, JC; Medema, JP; Mehlen, P; Meier, P; Melino, S; Miao, EA; Molkentin, JD; Moll, UM; Muñoz-Pinedo, C; Nagata, S; Nuñez, G; Oberst, A; Oren, M; Overholtzer, M; Pagano, M; Panaretakis, T; Pasparakis, M; Penninger, JM; Pereira, DM; Pervaiz, S; Peter, ME; Piacentini, M; Pinton, P; Prehn, JHM; Puthalakath, H; Rabinovich, GA; Rehm, M; Rizzuto, R; Rodrigues, CMP; Rubinsztein, DC; Rudel, T; Ryan, KM; Sayan, E; Scorrano, L; Shao, F; Shi, Y; Silke, J; Simon, HU; Sistigu, A; Stockwell, BR; Strasser, A; Szabadkai, G; Tait, SWG; Tang, D; Tavernarakis, N; Thorburn, A; Tsujimoto, Y; Turk, B; Vanden Berghe, T; Vandenabeele, P; Vander Heiden, MG; Villunger, A; Virgin, HW; Vousden, KH; Vucic, D; Wagner, EF; Walczak, H; Wallach, D; Wang, Y; Wells, JA; Wood, W; Yuan, J; Zakeri, Z; Zhivotovsky, B; Zitvogel, L; Melino, G; Kroemer, G
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Cell Death Differ. 2018; 25(3):486-541
Doi: 10.1038/s41418-017-0012-4
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** Lier, A; Penzel, R; Heining, C; Horak, P; Frohlich, M; Uhrig, S; Budczies, J; Kirchner, M; Volckmar, AL; Hutter, B; Kreutzfeldt, S; Endris, V; Richter, D; Wolf, S; Pfutze, K; Neumann, O; Buchhalter, I; de Oliveira, CMM; Singer, S; Leichsenring, J; Herpel, E; Klauschen, F; Jost, PJ; Metzeler, KH; Schulze-Osthoff, K; Kopp, HG; Kindler, T; Rieke, DT; Lamping, M; Brandts, C; Falkenhorst, J; Bauer, S; Schrock, E; Folprecht, G; Boerries, M; von Bubnoff, N; Weichert, W; Brors, B; Lichter, P; von Kalle, C; Schirmacher, P; Glimm, H; Frohling, S; Stenzinger, A
Validating Comprehensive Next-Generation Sequencing Results for Precision Oncology: The NCT/DKTK Molecularly Aided Stratification for Tumor Eradication Research Experience
JCO PRECIS ONCOL. 2018; 2:
Doi: 10.1200/PO.18.00171
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** Moog, P; Jost, PJ; Büttner-Herold, M
Eculizumab as salvage therapy for recurrent monoclonal gammopathy-induced C3 glomerulopathy in a kidney allograft.
BMC Nephrol. 2018; 19(1):106-106
Doi: 10.1186/s12882-018-0904-7
(- Case Report)
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** Reidel, V; Kauschinger, J; Hauch, RT; Müller-Thomas, C; Nadarajah, N; Burgkart, R; Schmidt, B; Hempel, D; Jacob, A; Slotta-Huspenina, J; Höckendorf, U; Peschel, C; Kern, W; Haferlach, T; Götze, KS; Jilg, S; Jost, PJ
Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile.
Oncotarget. 2018; 9(25):17270-17281
Doi: 10.18632/oncotarget.24775
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** Rinaldetti, S; Pfirrmann, M; Manz, K; Guilhot, J; Dietz, C; Panagiotidis, P; Spiess, B; Seifarth, W; Fabarius, A; Müller, M; Pagoni, M; Dimou, M; Dengler, J; Waller, CF; Brümmendorf, TH; Herbst, R; Burchert, A; Janβen, C; Goebeler, ME; Jost, PJ; Hanzel, S; Schafhausen, P; Prange-Krex, G; Illmer, T; Janzen, V; Klausmann, M; Eckert, R; Büschel, G; Kiani, A; Hofmann, WK; Mahon, FX; Saussele, S
Effect of ABCG2, OCT1, and ABCB1 (MDR1) Gene Expression on Treatment-Free Remission in a EURO-SKI Subtrial.
Clin Lymphoma Myeloma Leuk. 2018; 18(4):266-271
Doi: 10.1016/j.clml.2018.02.004
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** Jilg, S; Hauch, RT; Wahida, A; Kauschinger, J; Buschhorn, L; Odinius, T; Reidel, V; Schmid, B; Hempel, D; Hollein, A; Peschel, C; Bassermann, F; Slotta-Huspenina, J; Hockendorf, U; Jost, PJ
Stage-dependent role of pro-necroptotic RIPK1/3 in patients with MDS and CMML
ONCOL RES TREAT. 2018; 41: 94-94.
Web of Science
** Muller, N; Fischer, J; Haas, T; Poeck, H; Yabal, M; Jost, PJ
RIPK3 as an essential mediator of inflammation and cell death which facilitates IL-17 induction in innate and adaptive T lymphocyte subsets
EUR J IMMUNOL. 2018; 48: 121-121.
Web of Science
** Pfarr, N; Boxberg, M; Riedmann, K; Jesinghaus, M; Konukiewitz, B; Glimm, H; Jost, PJ; Frohling, S; Weichert, W
Reliability of the detection of the mutation burden status by targeted next generation sequencing applying a large gene panel
ANN ONCOL. 2018; 29:
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** Boege, Y; Malehmir, M; Healy, ME; Bettermann, K; Lorentzen, A; Vucur, M; Ahuja, AK; Böhm, F; Mertens, JC; Shimizu, Y; Frick, L; Remouchamps, C; Mutreja, K; Kähne, T; Sundaravinayagam, D; Wolf, MJ; Rehrauer, H; Koppe, C; Speicher, T; Padrissa-Altés, S; Maire, R; Schattenberg, JM; Jeong, JS; Liu, L; Zwirner, S; Boger, R; Hüser, N; Davis, RJ; Müllhaupt, B; Moch, H; Schulze-Bergkamen, H; Clavien, PA; Werner, S; Borsig, L; Luther, SA; Jost, PJ; Weinlich, R; Unger, K; Behrens, A; Hillert, L; Dillon, C; Di Virgilio, M; Wallach, D; Dejardin, E; Zender, L; Naumann, M; Walczak, H; Green, DR; Lopes, M; Lavrik, I; Luedde, T; Heikenwalder, M; Weber, A
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.
Cancer Cell. 2017; 32(3):342-359
Doi: 10.1016/j.ccell.2017.08.010
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** Höckendorf, U; Yabal, M; Jost, PJ
Killing AML: RIPK3 leads the way.
Cell Cycle. 2017; 16(1):3-4
Doi: 10.1080/15384101.2016.1232069
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** Holch, JW; Metzeler, KH; Jung, A; Riedmann, K; Jost, PJ; Weichert, W; Kirchner, T; Heinemann, V; Westphalen, CB
Universal Genomic Testing: The next step in oncological decision-making or a dead end street?
Eur J Cancer. 2017; 82(3):72-79
Doi: 10.1016/j.ejca.2017.05.034
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** Lawlor, KE; Feltham, R; Yabal, M; Conos, SA; Chen, KW; Ziehe, S; Graß, C; Zhan, Y; Nguyen, TA; Hall, C; Vince, AJ; Chatfield, SM; D'Silva, DB; Pang, KC; Schroder, K; Silke, J; Vaux, DL; Jost, PJ; Vince, JE
XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.
Cell Rep. 2017; 20(3):668-682
Doi: 10.1016/j.celrep.2017.06.073
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** Hockendorf, U; Yabal, M; Jost, PJ
RIPK3-Dependent Cell Death and Differentiation of Leukemia Initiating Cells Restrict Myeloid Leukemogenesis
ANN HEMATOL. 2017; 96: S50-S50.
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** Jilg, S; Kauschinger, J; Hauch, RT; Reidel, V; Muller-Thomas, C; Schmidt, B; Hockendorf, U; Peschel, C; Gotze, KS; Jost, PJ
Inhibition of Polo-like Kinase 1 effectively induces cell death in MDS, CMML-1/-2 and sAML while sparing the healthy heamatopoiesis
ONCOL RES TREAT. 2017; 40: 179-179.
Web of Science
** Jilg, S; Reidel, V; Kauschinger, J; Muller-Thomas, C; Hauch, R; Schauwecker, J; Burkhard, S; Hockendorf, U; Peschel, C; Kern, W; Haferlach, T; Slotta-Huspenina, J; Gotze, KS; Jost, PJ
BCL-2 INHIBITION BY ABT-199 POTENTLY INDUCES CELL DEATH IN MDS PROGENITORS DESPITE HIGH-RISK MUTATIONS IN ASXL1, RUNX1, TP53 OR EZH2
LEUKEMIA RES. 2017; 55: S156-S156.
Doi: 10.1016/S0145-2126(17)30385-5
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** Jost, PJ; Yabal, M; Hockendorf, U
Inflammation and cell death controls AML development, phenotype and outcome
ONCOL RES TREAT. 2017; 40: 54-54.
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** Rinaldetti, S; Pfirrmann, M; Manz, K; Guilhot, J; Panagiotidis, P; Spiess, B; Seifarth, W; Fabarius, A; Pagoni, M; Dimou, M; Dengler, J; Waller, C; Brummendorf, TH; Herbst, R; Burchert, A; Janssen, C; Goebeler, ME; Jost, PJ; Hanzel, S; Schafhausen, P; Prange-Krex, G; Illmer, T; Janzen, V; Klausmann, M; Eckert, R; Buschel, G; Kiani, A; Hofmann, WK; Mahon, FX; Saussele, S
IMPACT OF ABCG2, OCT1 AND ABCB1 (MDR1) ON TREATMENT FREE REMISSION IN AN EUROSKI SUBTRIAL
HAEMATOLOGICA. 2017; 102: 74-74.
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** Engel, K; Rudelius, M; Slawska, J; Jacobs, L; Ahangarian Abhari, B; Altmann, B; Kurutz, J; Rathakrishnan, A; Fernández-Sáiz, V; Brunner, A; Targosz, BS; Loewecke, F; Gloeckner, CJ; Ueffing, M; Fulda, S; Pfreundschuh, M; Trümper, L; Klapper, W; Keller, U; Jost, PJ; Rosenwald, A; Peschel, C; Bassermann, F
USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.
EMBO Mol Med. 2016; 8(8):851-862
Doi: 10.15252/emmm.201506047
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** Fernández-Marrero, Y; Spinner, S; Kaufmann, T; Jost, PJ
Survival control of malignant lymphocytes by anti-apoptotic MCL-1.
Leukemia. 2016; 30(11):2152-2159
Doi: 10.1038/leu.2016.213
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** Höckendorf, U; Yabal, M; Herold, T; Munkhbaatar, E; Rott, S; Jilg, S; Kauschinger, J; Magnani, G; Reisinger, F; Heuser, M; Kreipe, H; Sotlar, K; Engleitner, T; Rad, R; Weichert, W; Peschel, C; Ruland, J; Heikenwalder, M; Spiekermann, K; Slotta-Huspenina, J; Groß, O; Jost, PJ
RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.
Cancer Cell. 2016; 30(1):75-91
Doi: 10.1016/j.ccell.2016.06.002
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** Höckendorf, U; Yabal, M; Jost, PJ
RIPK3-dependent cell death and inflammasome activation in FLT3-ITD expressing LICs.
Oncotarget. 2016; 7(36):57483-57484
Doi: 10.18632/oncotarget.11195
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** Hrdinka, M; Fiil, BK; Zucca, M; Leske, D; Bagola, K; Yabal, M; Elliott, PR; Damgaard, RB; Komander, D; Jost, PJ; Gyrd-Hansen, M
CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.
Cell Rep. 2016; 14(12):2846-2858
Doi: 10.1016/j.celrep.2016.02.062
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** Jilg, S; Reidel, V; Müller-Thomas, C; König, J; Schauwecker, J; Höckendorf, U; Huberle, C; Gorka, O; Schmidt, B; Burgkart, R; Ruland, J; Kolb, HJ; Peschel, C; Oostendorp, RA; Götze, KS; Jost, PJ
Blockade of BCL-2 proteins efficiently induces apoptosis in progenitor cells of high-risk myelodysplastic syndromes patients.
Leukemia. 2016; 30(1):112-123
Doi: 10.1038/leu.2015.179
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** Spinner, S; Crispatzu, G; Yi, JH; Munkhbaatar, E; Mayer, P; Höckendorf, U; Müller, N; Li, Z; Schader, T; Bendz, H; Hartmann, S; Yabal, M; Pechloff, K; Heikenwalder, M; Kelly, GL; Strasser, A; Peschel, C; Hansmann, ML; Ruland, J; Keller, U; Newrzela, S; Herling, M; Jost, PJ
Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance.
Leukemia. 2016; 30(7):1520-1530
Doi: 10.1038/leu.2016.49
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** Wicki, S; Gurzeler, U; Wei-Lynn Wong, W; Jost, PJ; Bachmann, D; Kaufmann, T
Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils.
Cell Death Dis. 2016; 7(10):e2422-e2422
Doi: 10.1038/cddis.2016.311
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** Ahmadova, G; Kreil, S; Jost, PJ; Keller, P; Wolfensberger, N; Maschke, A; Schonberger, B; Haferlach, T; Schwaab, J; Naumann, N; Jahwar, M; Cross, NCP; Fabarius, A; Hofmann, WK; Haferlach, C; Reiter, A; Metzgeroth, G
Clinical characteristics and treatment with tyrosine kinase inhibitors in four patients with ETV6-ABL1 positive eosinophilia-associated myeloproliferative neoplasms
ONCOL RES TREAT. 2016; 39: 232-233.
Web of Science
** Glauche, I; Liebscher, H; Baldow, C; Kuhn, M; Schulze, P; Haehnel, T; Voskanyan, A; Guilhot, J; Dulucq, S; von Bubnoff, N; Saussele, S; Mustjoki, S; Jost, PJ; Guilhot, F; Mahon, FX; Roeder, I
A New Computational Method to Predict Long-Term Minimal Residual Disease and Molecular Relapse after TKI-Cessation in CML
BLOOD. 2016; 128(22):
Doi: 10.1182/blood.V128.22.3099.3099
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** Hockendorf, U; Monica, Y; Peschel, C; Jost, PJ
Evasion of Necroptosis and Inflammasome Activation Promotes Myeloid Leukemogenesis
BLOOD. 2016; 128(22):
Doi: 10.1182/blood.V128.22.2856.2856
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** Jilg, S; Kauschinger, J; Reidel, V; Muller-Thomas, C; Hauch, R; Schauwecker, J; Schmidt, B; Hockendorf, U; Peschel, C; Gotze, K; Jost, PJ
Combination of 5-Azacytidine and ABT-199 Has a Synergistic Apoptotic Effect in High-Risk MDS/sAML after HMA Failure
BLOOD. 2016; 128(22):
Doi: 10.1182/blood.V128.22.4297.4297
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** Reiter, A; Ahmadova, G; Jawhar, M; Virchis, A; Somervaille, T; Williams, M; Schonberger, B; Frewin, R; Jost, PJ; Maschke, A; Keller, P; Haferlach, T; Naumann, N; Schwaab, J; Fabarius, A; Hofmann, WK; Haferlach, C; Cross, NCP; Metzgeroth, G
Clinical Characteristics and Treatment with Various Tyrosine Kinase Inhibitors in Patients with ETV6-ABL1 positive Eosinophilia-Associated Myeloproliferative Neoplasms
BLOOD. 2016; 128(22):
Doi: 10.1182/blood.V128.22.3114.3114
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** Saussele, S; Mahon, FX; Guilhot, J; Dengler, J; Waller, CT; Brummendorf, TH; Herbst, R; Burchert, A; Goebeler, ME; Freunek, G; Prummer, O; Jost, PJ; Prange-Krex, G; Illmer, T; Janzen, V; Schafhausen, P; Klausmann, M; Kiani, A; Eckert, R; de Wit, M; Janssen, C; Muller, MC; Hochhaus, A; Richter, J; Pfirrmann, M
Stopping tyrosine kinase inhibitors in a large cohort of European chronic myeloid leukemia (CML) patients: results of the EURO-SKI trial
ONCOL RES TREAT. 2016; 39: 209-209.
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** Galluzzi, L; Bravo-San Pedro, JM; Vitale, I; Aaronson, SA; Abrams, JM; Adam, D; Alnemri, ES; Altucci, L; Andrews, D; Annicchiarico-Petruzzelli, M; Baehrecke, EH; Bazan, NG; Bertrand, MJ; Bianchi, K; Blagosklonny, MV; Blomgren, K; Borner, C; Bredesen, DE; Brenner, C; Campanella, M; Candi, E; Cecconi, F; Chan, FK; Chandel, NS; Cheng, EH; Chipuk, JE; Cidlowski, JA; Ciechanover, A; Dawson, TM; Dawson, VL; De Laurenzi, V; De Maria, R; Debatin, KM; Di Daniele, N; Dixit, VM; Dynlacht, BD; El-Deiry, WS; Fimia, GM; Flavell, RA; Fulda, S; Garrido, C; Gougeon, ML; Green, DR; Gronemeyer, H; Hajnoczky, G; Hardwick, JM; Hengartner, MO; Ichijo, H; Joseph, B; Jost, PJ; Kaufmann, T; Kepp, O; Klionsky, DJ; Knight, RA; Kumar, S; Lemasters, JJ; Levine, B; Linkermann, A; Lipton, SA; Lockshin, RA; López-Otín, C; Lugli, E; Madeo, F; Malorni, W; Marine, JC; Martin, SJ; Martinou, JC; Medema, JP; Meier, P; Melino, S; Mizushima, N; Moll, U; Muñoz-Pinedo, C; Nuñez, G; Oberst, A; Panaretakis, T; Penninger, JM; Peter, ME; Piacentini, M; Pinton, P; Prehn, JH; Puthalakath, H; Rabinovich, GA; Ravichandran, KS; Rizzuto, R; Rodrigues, CM; Rubinsztein, DC; Rudel, T; Shi, Y; Simon, HU; Stockwell, BR; Szabadkai, G; Tait, SW; Tang, HL; Tavernarakis, N; Tsujimoto, Y; Vanden Berghe, T; Vandenabeele, P; Villunger, A; Wagner, EF; Walczak, H; White, E; Wood, WG; Yuan, J; Zakeri, Z; Zhivotovsky, B; Melino, G; Kroemer, G
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.
Cell Death Differ. 2015; 22(1):58-73
Doi: 10.1038/cdd.2014.137
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** Yabal, M; Jost, PJ
XIAP as a regulator of inflammatory cell death: the TNF and RIP3 angle.
Mol Cell Oncol. 2015; 2(1):e964622-e964622
Doi: 10.4161/23723548.2014.964622
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** Jilg, S; Reidel, V; Muller-Thomas, C; Hockendorf, U; Huberle, C; Peschel, C; Oostendorp, RA; Gotze, KS; Jost, PJ
MCL-1 conveys resistance to ABT-199 in primary MDS samples
ONCOL RES TREAT. 2015; 38: 260-260.
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** Tweedell, RE; Bergmann-Leitner, ES; Tao, DY; King, JG; Robinson, TM; Bingham, K; Lanar, DE; Jost, PJ; Boddey, JA; Dinglasan, RR
OPTIMIZED PLASMODIUM FALCIPARUM HEPATOCYTE INFECTION MODEL FACILITATES DRUG AND VACCINE DEVELOPMENT
AM J TROP MED HYG. 2015; 93(4): 290-290.
Web of Science
** Schweneker, K; Clemm, C; Brügel, M; Souvatzoglou, M; Hermisson, M; Schmidt-Graf, F; Zimmer, C; Peschel, C; Jost, PJ
Effective long-term treatment with bevacizumab for relapsed glioblastoma: case report and review of the literature.
Exp Hematol Oncol. 2014; 3(16):29-29
Doi: 10.1186/2162-3619-3-29
(- Case Report)
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** Tao, D; King, JG; Tweedell, RE; Jost, PJ; Boddey, JA; Dinglasan, RR
The acute transcriptomic and proteomic response of HC-04 hepatoma cells to hepatocyte growth factor and its implications for Plasmodium falciparum sporozoite invasion.
Mol Cell Proteomics. 2014; 13(5):1153-1164
Doi: 10.1074/mcp.M113.035584
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** Wong, WW; Vince, JE; Lalaoui, N; Lawlor, KE; Chau, D; Bankovacki, A; Anderton, H; Metcalf, D; O'Reilly, L; Jost, PJ; Murphy, JM; Alexander, WS; Strasser, A; Vaux, DL; Silke, J
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner.
Blood. 2014; 123(16):2562-2572
Doi: 10.1182/blood-2013-06-510743
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** Yabal, M; Müller, N; Adler, H; Knies, N; Groß, CJ; Damgaard, RB; Kanegane, H; Ringelhan, M; Kaufmann, T; Heikenwälder, M; Strasser, A; Groß, O; Ruland, J; Peschel, C; Gyrd-Hansen, M; Jost, PJ
XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.
Cell Rep. 2014; 7(6):1796-1808
Doi: 10.1016/j.celrep.2014.05.008
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** Jost, PJ; Yabal, M; Adler, H; Knies, N; Gross, C; Damgaard, RB; Kanegane, H; Peschel, C; Strasser, A; Gross, O; Ruland, J; Gyrd-Hansen, M
A Mouse Model for XLP-2 Disease Uncovers a Critical Function for IL-1beta and TNF in Driving Hyper-Inflammation
BLOOD. 2014; 124(21):
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** Yabal, M; Muller, N; Adler, H; Knies, N; Gross, CJ; Damgaard, RB; Kanegane, H; Ringelhan, M; Kaufmann, T; Heikenwalder, M; Strasser, A; Gross, O; Ruland, J; Peschel, C; Gyrd-Hansen, M; Jost, PJ
Aberrant TNF signalling in dendritic cells in the absence of XIAP contributes to X-linked lymphoproliferative disease (XLP-2) by exaggerated necroptosis
ONCOL RES TREAT. 2014; 37: 246-246.
Web of Science
** Damgaard, RB; Fiil, BK; Speckmann, C; Yabal, M; zur Stadt, U; Bekker-Jensen, S; Jost, PJ; Ehl, S; Mailand, N; Gyrd-Hansen, M
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.
EMBO Mol Med. 2013; 5(8):1278-1295
Doi: 10.1002/emmm.201303090
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** Venjakob, AJ; Vogt, S; Stöckl, K; Tischer, T; Jost, PJ; Thein, E; Imhoff, AB; Anetzberger, H
Local cooling reduces regional bone blood flow.
J Orthop Res. 2013; 31(11):1820-1827
Doi: 10.1002/jor.22417
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** Vogt, S; Venjakob, AJ; Stöckl, K; Tischer, T; Jost, PJ; Imhoff, AB; Thein, E; Anetzberger, H
Evidence of an autoregulatory mechanism of regional bone blood flow at hypotension.
Arch Orthop Trauma Surg. 2013; 133(9):1233-1241
Doi: 10.1007/s00402-013-1801-y
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** Jilg, S; Konig, J; Hockendorf, U; Schauwecker, J; Huberle, C; Muller-Thomas, C; Schmidt, B; Burgkart, R; Gotze, K; Kolb, HJ; Peschel, C; Jost, PJ
Resistance to apoptosis in high-risk myelodysplastic syndrome can be overcome by pro-apoptotic drug treatment using ABT-737
LEUKEMIA RES. 2013; 37: S29-S30.
Doi: 10.1016/S0145-2126(13)70065-1
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** Jilg, S; Konig, J; Hockendorf, U; Schauwecker, J; Huberle, C; Muller-Thomas, C; Schmidt, B; Burgkart, R; Kolb, HJ; Gotze, K; Peschel, C; Jost, PJ
Pharmacologic intervention with the pro-apoptotic compound ABT-737 potently induces apoptosis in high-risk MDS/sAML bone marrow cells
ONKOLOGIE. 2013; 36: 124-125.
Web of Science
** Damgaard, RB; Nachbur, U; Yabal, M; Wong, WW; Fiil, BK; Kastirr, M; Rieser, E; Rickard, JA; Bankovacki, A; Peschel, C; Ruland, J; Bekker-Jensen, S; Mailand, N; Kaufmann, T; Strasser, A; Walczak, H; Silke, J; Jost, PJ; Gyrd-Hansen, M
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.
Mol Cell. 2012; 46(6):746-758
Doi: 10.1016/j.molcel.2012.04.014
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** Kaufmann, T; Strasser, A; Jost, PJ
Fas death receptor signalling: roles of Bid and XIAP.
Cell Death Differ. 2012; 19(1):42-50
Doi: 10.1038/cdd.2011.121
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** Jost, PJ; Spinner, S; Kelly, G; Herold, M; Yabal, M; Strasser, A; Peschel, C
The role of the anti-apoptotic Bcl-2 proteins Bcl-x(L) and Mcl-1 in survival of T-cell Non-Hodgkin's lymphoma
ONKOLOGIE. 2012; 35: 4-4.
Web of Science
** Yabal, M; Damgaard, RB; Nachbur, U; Ruland, J; Peschel, C; Strasser, A; Silke, J; Gyrd-Hansen, M; Jost, PJ
Inhibition of NOD2 signalling by mutations in the RING domain of XIAP contribute to development of X-linked lymphoproliferative syndrome
ONKOLOGIE. 2011; 34: 113-113.
Web of Science
** Jost, PJ; Kaufmann, T
Cancer caused by too much apoptosis--an intriguing contradiction?
Hepatology. 2010; 51(4):1110-1112
Doi: 10.1002/hep.23514
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** Vikstrom, I; Carotta, S; Lüthje, K; Peperzak, V; Jost, PJ; Glaser, S; Busslinger, M; Bouillet, P; Strasser, A; Nutt, SL; Tarlinton, DM
Mcl-1 is essential for germinal center formation and B cell memory.
Science. 2010; 330(6007):1095-1099
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** Jost, PJ; Nachbur, U; Grabow, S; Huang, DC; Bouillet, P; Silke, J; Strasser, A; Kaufmann, T
Anti-cancer SMAC-mimetic compounds accelerate hepatocyte cell death upon FAS or TNF-alpha signalling
ONKOLOGIE. 2010; 33: 63-64.
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** Bianchi, K; Jost, PJ; Kaufmann, T; Rutkowski, R
International EMBO Workshop on 'Model Organisms in Cell Death Research', Obergurgl (Austria).
Cell Death Differ. 2009; 16(8):1180-1183
Doi: 10.1038/cdd.2009.60
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** Jost, PJ; Grabow, S; Gray, D; McKenzie, MD; Nachbur, U; Huang, DC; Bouillet, P; Thomas, HE; Borner, C; Silke, J; Strasser, A; Kaufmann, T
XIAP discriminates between type I and type II FAS-induced apoptosis.
Nature. 2009; 460(7258):1035-1039
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** Kaufmann, T; Jost, PJ; Pellegrini, M; Puthalakath, H; Gugasyan, R; Gerondakis, S; Cretney, E; Smyth, MJ; Silke, J; Hakem, R; Bouillet, P; Mak, TW; Dixit, VM; Strasser, A
Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.
Immunity. 2009; 30(1):56-66
Doi: 10.1016/j.immuni.2008.10.017
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** Strasser, A; Jost, PJ; Nagata, S
The many roles of FAS receptor signaling in the immune system.
Immunity. 2009; 30(2):180-192
Doi: 10.1016/j.immuni.2009.01.001
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** Jost, PJ; Ruland, J
Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications.
Blood. 2007; 109(7):2700-2707
Doi: 10.1182/blood-2006-07-025809
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** Jost, PJ; Weiss, S; Ferch, U; Gross, O; Mak, TW; Peschel, C; Ruland, J
Bcl10/Malt1 signaling is essential for TCR-induced NF-kappaB activation in thymocytes but dispensable for positive or negative selection.
J Immunol. 2007; 178(2):953-960
Doi: 10.4049/jimmunol.178.2.953
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** Jost, PJ; Stengel, SM; Huber, W; Sarbia, M; Peschel, C; Duyster, J
Very severe iron-deficiency anemia in a patient with celiac disease and bulimia nervosa: a case report.
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Doi: 10.1532/IJH97.E0505
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** Jost, PJ; Ferch, U; Weiss, S; Leeder, S; Gross, O; Mak, TW; Peschel, C; Ruland, J
Functional and molecular analysis of maturation of thymocytes in Bcl10 or Malt1 deficient mice.
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Report of a male patient with brain metastases from breast cancer.
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A novel peptide, THALWHT, for the targeting of human airway epithelia.
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