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Sill Heinz |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Foßelteder, J; Brauchart, T; Schlacher, A; Sconocchia, T; Özkaya, E; Auinger, L; Schlenke, P; Sill, H; Zebisch, A; Reinisch, A Engineered cytokine-expressing MSCs support ex vivo culture of human HSPCs and AML cells.
Exp Hematol. 2025; 104790 Doi: 10.1016/j.exphem.2025.104790
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2024

Originalarbeit (Zeitschrift)

** Edtmayer, S; Witalisz-Siepracka, A; Zdársky, B; Heindl, K; Weiss, S; Eder, T; Dutta, S; Graichen, U; Klee, S; Sharif, O; Wieser, R; Győrffy, B; Poli, V; Casanova, E; Sill, H; Grebien, F; Stoiber, D A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia.
Cell Death Dis. 2024; 15(5): 369 Doi: 10.1038/s41419-024-06749-9 [OPEN ACCESS]
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** Witalisz-Siepracka, A; Denk, CM; Zdársky, B; Hofmann, L; Edtmayer, S; Harm, T; Weiss, S; Heindl, K; Hessenberger, M; Summer, S; Dutta, S; Casanova, E; Obermair, GJ; Győrffy, B; Putz, EM; Sill, H; Stoiber, D STAT3 in acute myeloid leukemia facilitates natural killer cell-mediated surveillance.
Front Immunol. 2024; 15: 1374068 Doi: 10.3389/fimmu.2024.1374068 [OPEN ACCESS]
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** Wurm, S; Waltersdorfer, M; Loindl, S; Moritz, JM; Herzog, SA; Bachmaier, G; Berghold, A; Kashofer, K; Beham-Schmid, C; Hoefler, G; Greinix, HT; Wölfler, A; Reinisch, A; Sill, H; Zebisch, A Acute myeloid leukemia in the next-generation sequencing era : Real-world data from an Austrian tertiary cancer care center.
Wien Klin Wochenschr. 2024; Doi: 10.1007/s00508-024-02463-w
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Übersichtsarbeit

** Moritz, J; Schwab, A; Reinisch, A; Zebisch, A; Sill, H; Wölfler, A Measurable Residual Disease Detection in Acute Myeloid Leukemia: Current Challenges and Future Directions.
Biomedicines. 2024; 12(3): 599 Doi: 10.3390/biomedicines12030599 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Cutillas, PR; Borek, WE; Christopher, JA; Nobre, LV; Campbell, A; Kelsall, J; Pedicona, F; Nawaz, N; Perkins, DN; Cardoso, PM; Arruda, A; Ambinder, AJ; Dutta, S; Gallipoli, P; Sill, H; Ghiaur, G; Minden, MD; Williamson, A; Gribben, JG; Dokal, AD Multi-drug algorithm to accurately predict best first-line treatments in newly-diagnosed acute myeloid leukemia (AML)
J CLIN ONCOL. 2024; 42(16): [Poster]
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** Edtmayer, S; Witalisz-Siepracka, A; Zdársky, B; Weiss, S; Eder, T; Dutta, S; Wieser, R; Sill, H; Grebien, F; Stoiber, D STAT3β represses interferon signaling in acute myeloid leukemia contributing to favorable disease outcomes
KLIN PADIATR. Abstracts. 2024; 236(3):204-204.-35. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung; JUN 5-8, 2024; Wilsede, GERMANY. Doi: 10.1055/s-0044-1786570 [Poster]
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2023

Originalarbeit (Zeitschrift)

** Foßelteder, J; Pabst, G; Sconocchia, T; Schlacher, A; Auinger, L; Kashofer, K; Beham-Schmid, C; Trajanoski, S; Waskow, C; Schöll, W; Sill, H; Zebisch, A; Wölfler, A; Thomas, D; Reinisch, A Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.
Leukemia. 2023; 37(4): 843-853. Doi: 10.1038/s41375-023-01848-6 [OPEN ACCESS]
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** Pleyer, L; Vaisband, M; Drost, M; Pfeilstöcker, M; Stauder, R; Heibl, S; Sill, H; Girschikofsky, M; Stampfl-Mattersberger, M; Pichler, A; Hartmann, B; Petzer, A; Schreder, M; Schmitt, CA; Vallet, S; Melchardt, T; Zebisch, A; Pichler, P; Zaborsky, N; Machherndl-Spandl, S; Wolf, D; Keil, F; Hasenauer, J; Larcher-Senn, J; Greil, R Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine-A prospective cohort study by the AGMT.
Am J Hematol. 2023; Doi: 10.1002/ajh.27046
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** Sconocchia, T; Foßelteder, J; Auinger, L; Özkaya, E; Benezeder, T; Lang, M; Beham-Schmid, C; Hoefler, G; Zebisch, A; Wölfler, A; Sill, H; Wolf, P; Strobl, H; Reinisch, A BRAF^V600E promotes DC3/monocyte differentiation in human gene-engineered HSPCs and causes multisystem histiocytosis.
Leukemia. 2023; 37(11): 2292-2296. Doi: 10.1038/s41375-023-02019-3 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Kuendgen, A; Nomdedeu, M; Tuechler, H; Garcia-Manero, G; Komrokji, R; Sekeres, M; Della Porta, M; Cazzola, M; Dezern, A; Roboz, G; Steensma, D; Van De Loosdrecht, A; Malcovati, L; Schlenk, R; Grau, J; Calvo, X; Blum, S; Pereira, A; Valent, P; Costa, D; Giagounidis, A; Xicoy, B; Dohner, H; Platzbecker, U; Pedro, C; Lubbert, M; Oiartzabal, I; Diez-Campelo, M; Cedena, MT; Machherndl-Spandl, S; Lopez-Pavia, M; Martinez-De-Sola, M; Stauder, R; Merchan, B; Ganster, C; Schroeder, T; Voso, MT; Pfeilstocker, M; Sill, H; Hildebrandt, B; Esteve, J; Cobo, F; Sole, F; Germing, U; Greenberg, P; Haase, D; Sanz, G A STEP TOWARDS IDENTIFICATION AND CAUSAL INTERPRETATION OF THERAPY-RELATED MDS (T-MDS)
LEUKEMIA RES. 2023; 128: 107226- Doi: 10.1016/j.leukres.2023.107226 [Oral Communication]
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** Lyssy, F; Lind, K; Zöscher, F; Zebisch, A; Wölfler, A; Pabst, G; Fosselteder, J; Reinisch, A; Sill, H; Dutta, S Modelling drug resistance conferred by mono- and bi-allelic TP53 aberrations using isogenic AML cell lines
ONCOL RES TREAT. 2023; 46: 188-189. [Poster]
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2022

Originalarbeit (Zeitschrift)

** Dutta, S; Moritz, J; Pregartner, G; Thallinger, GG; Brandstätter, I; Lind, K; Rezania, S; Lyssy, F; Reinisch, A; Zebisch, A; Berghold, A; Wölfler, A; Sill, H Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations.
Ann Hematol. 2022; 101(4):837-846 Doi: 10.1007/s00277-022-04766-2 [OPEN ACCESS]
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** Geissler, K; Jäger, E; Barna, A; Gurbisz, M; Marschon, R; Graf, T; Nösslinger, T; Pfeilstöcker, M; Machherndl-Spandl, S; Stauder, R; Zebisch, A; Sill, H; Öhler, L; Kusec, R; Hoermann, G; Valent, P Multistep pathogenesis of chronic myelomonocytic leukemia in patients.
Eur J Haematol. 2022; 109(1):50-57 Doi: 10.1111/ejh.13768 [OPEN ACCESS]
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** Leisch, M; Pfeilstöcker, M; Stauder, R; Heibl, S; Sill, H; Girschikofsky, M; Stampfl-Mattersberger, M; Tinchon, C; Hartmann, B; Petzer, A; Schreder, M; Kiesl, D; Vallet, S; Egle, A; Melchardt, T; Piringer, G; Zebisch, A; Machherndl-Spandl, S; Wolf, D; Keil, F; Drost, M; Greil, R; Pleyer, L Adverse Events in 1406 Patients Receiving 13,780 Cycles of Azacitidine within the Austrian Registry of Hypomethylating Agents-A Prospective Cohort Study of the AGMT Study-Group.
Cancers (Basel). 2022; 14(10): Doi: 10.3390/cancers14102459 [OPEN ACCESS]
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Kurzbericht/Letter

** Meszaros, N; Lind, K; Sehlke, R; Vilagos, B; Krall, N; Vladimer, GI; Sill, H Influence of cryopreservation on drug responses and gene expression of AML cells: Implications for the use of biobanked tissues
BRIT J HAEMATOL. 2022; Doi: 10.1111/bjh.18557 [OPEN ACCESS]
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Editorial

** Zebisch, A; Sill, H How do non-coding RNAs impact treatment regimens currently being used in AML?
Expert Rev Anticancer Ther. 2022; 22(4):331-333 Doi: 10.1080/14737140.2022.2049764
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Korrektur

** Lin, WY; Fordham, SE; Hungate, E; Sunter, NJ; Elstob, C; Xu, Y; Park, C; Quante, A; Strauch, K; Gieger, C; Skol, A; Rahman, T; Sucheston-Campbell, L; Wang, J; Hahn, T; Clay-Gilmour, AI; Jones, GL; Marr, HJ; Jackson, GH; Menne, T; Collin, M; Ivey, A; Hills, RK; Burnett, AK; Russell, NH; Fitzgibbon, J; Larson, RA; Le, Beau, MM; Stock, W; Heidenreich, O; Alharbi, A; Allsup, DJ; Houlston, RS; Norden, J; Dickinson, AM; Douglas, E; Lendrem, C; Daly, AK; Palm, L; Piechocki, K; Jeffries, S; Bornhäuser, M; Röllig, C; Altmann, H; Ruhnke, L; Kunadt, D; Wagenführ, L; Cordell, HJ; Darlay, R; Andersen, MK; Fontana, MC; Martinelli, G; Marconi, G; Sanz, MA; Cervera, J; Gómez-Seguí, I; Cluzeau, T; Moreilhon, C; Raynaud, S; Sill, H; Voso, MT; Lo-Coco, F; Dombret, H; Cheok, M; Preudhomme, C; Gale, RE; Linch, D; Gaal-Wesinger, J; Masszi, A; Nowak, D; Hofmann, WK; Gilkes, A; Porkka, K; Milosevic, Feenstra, JD; Kralovics, R; Grimwade, D; Meggendorfer, M; Haferlach, T; Krizsán, S; Bödör, C; Stölzel, F; Onel, K; Allan, JM Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.
Nat Commun. 2022; 13(1): 2 Doi: 10.1038/s41467-021-27679-6 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Gaksch, L; Huber-Krassnitzer, B; Uhl, B; Bainschab, A; Sifferlinger, IA; Sill, H; Schlenke, P; Rosskopf, K; Beham-Schmid, C; Neumeister, P; Greinix, HT Autologous stem cell boost for prolonged severe cytopenia after treatment with cd19-car-t-cells for refractory diffuse large b-cell lymphoma -two case reports
BONE MARROW TRANSPL. 2022; 57(SUPPL 1): 141-142. [Poster]
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** Pleyer, L; Vaisband, M; Pfeilstocker, M; Stauder, R; Heibl, S; Sill, H; Girschikofsky, M; Stampfl-Mattersberger, M; Tinchon, C; Hartmann, BL; Petzer, A; Schreder, M; Schmitt, CA; Vallet, S; Melchardt, T; Scagnetti, L; Zebisch, A; Machherndl-Spandl, S; Wolf, D; Keil, F; Hasenauer, J; Greil, R Cox Proportional Hazards Deep Neural Network Identifies Peripheral Blood Complete Remission (PB-CR) to be at Least Equivalent to Morphologic CR in Predicting Outcomes of Patients Treated with Azacitidine - a Prospective Cohort Study By the AGMT
BLOOD. 2022; 140: 1346-1349. Doi: 10.1182/blood-2022-168521 [Oral Communication]
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2021

Originalarbeit (Zeitschrift)

** Berg, JL; Perfler, B; Hatzl, S; Mayer, MC; Wurm, S; Uhl, B; Reinisch, A; Klymiuk, I; Tierling, S; Pregartner, G; Bachmaier, G; Berghold, A; Geissler, K; Pichler, M; Hoefler, G; Strobl, H; Wölfler, A; Sill, H; Zebisch, A Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia.
Clin Epigenetics. 2021; 13(1): 1-1. Doi: 10.1186/s13148-020-00979-2 [OPEN ACCESS]
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** Berg, JL; Perfler, B; Hatzl, S; Uhl, B; Reinisch, A; Pregartner, G; Berghold, A; Penz, T; Schuster, M; Geissler, K; Prokesch, A; Müller-Tidow, C; Hoefler, G; Kashofer, K; Wölfler, A; Sill, H; Caraffini, V; Zebisch, A EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity.
Leukemia. 2021; 35(5):1521-1526 Doi: 10.1038/s41375-021-01161-0 [OPEN ACCESS]
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** Eisenwort, G; Sadovnik, I; Keller, A; Ivanov, D; Peter, B; Berger, D; Stefanzl, G; Bauer, K; Slavnitsch, K; Greiner, G; Gleixner, KV; Sperr, WR; Willmann, M; Sill, H; Bettelheim, P; Geissler, K; Deininger, M; Rülicke, T; Valent, P Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia.
Leukemia. 2021; 35(11):3176-3187 Doi: 10.1038/s41375-021-01227-z [OPEN ACCESS]
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** Grandits, AM; Nguyen, CH; Schlerka, A; Hackl, H; Sill, H; Etzler, J; Heyes, E; Stoiber, D; Grebien, F; Heller, G; Wieser, R Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness.
Leukemia. 2021; 35(10):2827-2839 Doi: 10.1038/s41375-021-01224-2 [OPEN ACCESS]
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** Kuendgen, A; Nomdedeu, M; Tuechler, H; Garcia-Manero, G; Komrokji, RS; Sekeres, MA; Della, Porta, MG; Cazzola, M; DeZern, AE; Roboz, GJ; Steensma, DP; Van, de, Loosdrecht, AA; Schlenk, RF; Grau, J; Calvo, X; Blum, S; Pereira, A; Valent, P; Costa, D; Giagounidis, A; Xicoy, B; Döhner, H; Platzbecker, U; Pedro, C; Lübbert, M; Oiartzabal, I; Díez-Campelo, M; Cedena, MT; Machherndl-Spandl, S; López-Pavía, M; Baldus, CD; Martinez-de-Sola, M; Stauder, R; Merchan, B; List, A; Ganster, C; Schroeder, T; Voso, MT; Pfeilstöcker, M; Sill, H; Hildebrandt, B; Esteve, J; Nomdedeu, B; Cobo, F; Haas, R; Sole, F; Germing, U; Greenberg, PL; Haase, D; Sanz, G Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS.
Leukemia. 2021; 35(3):835-849 Doi: 10.1038/s41375-020-0917-7 [OPEN ACCESS]
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** Lin, WY; Fordham, SE; Hungate, E; Sunter, NJ; Elstob, C; Xu, Y; Park, C; Quante, A; Strauch, K; Gieger, C; Skol, A; Rahman, T; Sucheston-Campbell, L; Wang, J; Hahn, T; Clay-Gilmour, AI; Jones, GL; Marr, HJ; Jackson, GH; Menne, T; Collin, M; Ivey, A; Hills, RK; Burnett, AK; Russell, NH; Fitzgibbon, J; Larson, RA; Le, Beau, MM; Stock, W; Heidenreich, O; Alharbi, A; Allsup, DJ; Houlston, RS; Norden, J; Dickinson, AM; Douglas, E; Lendrem, C; Daly, AK; Palm, L; Piechocki, K; Jeffries, S; Bornhäuser, M; Röllig, C; Altmann, H; Ruhnke, L; Kunadt, D; Wagenführ, L; Cordell, HJ; Darlay, R; Andersen, MK; Fontana, MC; Martinelli, G; Marconi, G; Sanz, MA; Cervera, J; Gómez-Seguí, I; Cluzeau, T; Moreilhon, C; Raynaud, S; Sill, H; Voso, MT; Lo-Coco, F; Dombret, H; Cheok, M; Preudhomme, C; Gale, RE; Linch, D; Gaal-Wesinger, J; Masszi, A; Nowak, D; Hofmann, WK; Gilkes, A; Porkka, K; Milosevic, Feenstra, JD; Kralovics, R; Grimwade, D; Meggendorfer, M; Haferlach, T; Krizsán, S; Bödör, C; Stölzel, F; Onel, K; Allan, JM Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.
Nat Commun. 2021; 12(1): 6233 Doi: 10.1038/s41467-021-26551-x [OPEN ACCESS]
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** Machherndl-Spandl, S; Jäger, E; Barna, A; Gurbisz, M; Marschon, R; Graf, T; Graf, E; Geissler, C; Hoermann, G; Nösslinger, T; Pfeilstöcker, M; Bettelheim, P; Zach, O; Weltermann, A; Heibl, S; Thaler, J; Zebisch, A; Sill, H; Stauder, R; Webersinke, G; Kusec, R; Ulsperger, E; Schneeweiss, B; Öhler, L; Germing, U; Valent, P; Tüchler, H; Geissler, K Impact of age on the cumulative risk of transformation in patients with chronic myelomonocytic leukaemia.
Eur J Haematol. 2021; 107(2):265-274 Doi: 10.1111/ejh.13647 [OPEN ACCESS]
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** Middeke, JM; Teipel, R; Röllig, C; Stasik, S; Zebisch, A; Sill, H; Kramer, M; Scholl, S; Hochhaus, A; Jost, E; Brümmendorf, TH; Naumann, R; Steffen, B; Serve, H; Altmann, H; Kunzmann, V; Einsele, H; Parmentier, S; Schaich, M; Burchert, A; Neubauer, A; Schliemann, C; Berdel, WE; Sockel, K; Stölzel, F; Platzbecker, U; Ehninger, G; Bornhäuser, M; Schetelig, J; Thiede, C, , Study, Alliance, Leukemia, (SAL) Decitabine treatment in 311 patients with acute myeloid leukemia: outcome and impact of TP53 mutations - a registry based analysis.
Leuk Lymphoma. 2021; 62(6):1432-1440 Doi: 10.1080/10428194.2020.1864354
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** van, der, Kouwe, E; Heller, G; Czibere, A; Pulikkan, JA; Agreiter, C; Castilla, LH; Delwel, R; Di, Ruscio, A; Ebralidze, AK; Forte, M; Grebien, F; Heyes, E; Kazianka, L; Klinger, J; Kornauth, C; Le, T; Lind, K; Barbosa, IAM; Pemovska, T; Pichler, A; Schmolke, AS; Schweicker, CM; Sill, H; Sperr, WR; Spittler, A; Surapally, S; Trinh, BQ; Valent, P; Vanura, K; Welner, RS; Zuber, J; Tenen, DG; Staber, PB Core-binding factor leukemia hijacks the T-cell-prone PU.1 antisense promoter.
Blood. 2021; 138(15):1345-1358 Doi: 10.1182/blood.2020008971 [OPEN ACCESS]
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Kurzbericht/Letter

** Mayer, MC; Berg, JL; Perfler, B; Hatzl, S; Herzog, SA; Bachmaier, G; Berghold, A; Reinisch, A; Wölfler, A; Sill, H; Zebisch, A miR-23a mediates resistance to hypomethylating agents in myeloid neoplasms.
ANN HEMATOL. 2021; 100(11): 2845-2847. Doi: 10.1007/s00277-021-04598-6
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Abstract (Zeitschrift)

** Foßelteder, J; Schlacher, A; Pabst, G; Amtmann, B; Schöll, W; Kashofer, K; Beham-Schmid, C; Schlenke, P; Greinix, HT; Sill, H; Woelfler, A; Zebisch, A; Reinisch, A Introduction and Genetic Correction of Calreticulin Mutations in Human Hematopoietic Stem and Progenitor Cells Sheds Light on MPN Pathogenesis
Blood. 2021; 138(S1):-Annual Meeting of the American Society of Hematology (ASH); DEC 11-14, 2021; Atlanta, USA. Doi: 10.1182/blood-2021-147919 [Poster]
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** Kuendgen, A; Nomdedeu, M; Tuechler, H; Garcia-Manero, G; Komrokji, R; Sekeres, M; Della Porta, M; Cazzola, M; Malcovati, L; Dezern, A; Roboz, G; Steensma, D; Haase, D; Stauder, R; Cedena, MT; De Loosdrecht, AV; Schlenk, R; Blum, S; Grau, J; Calvo, X; Valent, P; Costa, D; Pereira, A; Xicoy, B; Dohner, H; Platzbecker, U; Giagounidis, A; Pedro, C; Lubbert, M; Oiartzabal, I; Diez-Campelo, M; Machherndl-Spandl, S; Lopez-Pavia, M; Martinez-De-Sola, M; Merchan, B; Ganster, C; Schroeder, T; Voso, MT; Hildebrandt, B; Esteve, J; Nomdedeu, B; Cobo, F; Haas, R; Sole, F; Germing, U; Greenberg, P; Sill, H; Pfeilstocker, M; Sanz, G COMPARISON OF CYTOGENETIC ABERRATIONS IN 1590 PATIENTS WITH THERAPY-RELATED MDS (T-MDS) AND 4738 PATIENTS FROM THE REVISED INTERNATIONAL PROGNOSTIC SCORING SYSTEM DATABASE WITH PRIMARY-MDS (P-MDS)
LEUKEMIA RES. Abstracts Supplement. 2021; 108: S20-S21.-16th International Congress on Myelodysplastic Syndromes; SEP 23-26, 2021; Virtuell. [Poster]
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** Pabst, G; Foßelteder, J; Schlacher, A; Auinger, L; Martinez-Krams3, D; Ediriwickrema, A; Kashofer, K; Beham-Schmid, C; Greinix, HT; Woelfler, A; Schlenke, P; Sill, H; Zebisch, A; Majeti, R; Reinisch, A Modeling the Development of SRSF2 Mutated Myeloid Malignancies By CRISPR/Cas9 Mediated Genome Engineering of Primary Human Hematopoietic Stem and Progenitor Cells
Blood. 2021; 138(S1):-Annual Meeting of the American Society of Hematology (ASH); DEC 11-14, 2021; Atlanta, USA. Doi: 10.1182/blood-2021-149591 [Poster]
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** Pleyer, L; Pfeilstocker, M; Stauder, R; Heibl, S; Sill, H; Girschikofsky, M; Stampfl-Mattesberger, M; Tinchon, C; Hartmann, B; Petzer, A; Petricevic, B; Schmitt, CA; Vallet, S; Geissler, K; Sperr, WR; Leisch, M; Egle, A; Melchardt, T; Piringer, G; Zebisch, A; Machherndl-Spandl, S; Wolf, D; Keil, F; Angermann, H; Drost, M; Larcher-Senn, J; Greil, R Peripheral Blood Complete Remission Provides Added Value to the Classical Definition of Morphologic Complete Remission – a Prospective Cohort Study of 1441 Patients with MDS, CMML and AML Treated within the Austrian Azacitidine Registry
Englisch. 2021; 138(S1):-Annual Meeting of the American Society of Hematology (ASH); DEC 11-14, 2021; Atlanta, USA. Doi: 10.1182/blood-2021-145401 [Poster]
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2020

Originalarbeit (Zeitschrift)

** Anirudh, S; Rosenberger, A; Schwarzenberger, E; Schaefer, C; Strobl, H; Zebisch, A; Sill, H; Wölfler, A TNFα Rescues Dendritic Cell Development in Hematopoietic Stem and Progenitor Cells Lacking C/EBPα.
Cells. 2020; 9(5): Doi: 10.3390/cells9051223 [OPEN ACCESS]
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** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Schauer, S; Beham-Schmid, C; Hoefler, G; Geissler, K; Quehenberger, F; Kolch, W; Athineos, D; Blyth, K; Wölfler, A; Sill, H; Zebisch, A Loss of RAF kinase inhibitor protein is involved in myelomonocytic differentiation and aggravates RAS-driven myeloid leukemogenesis.
Haematologica. 2020; 105(2):375-386 Doi: 10.3324/haematol.2018.209650 [OPEN ACCESS]
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** Daga, S; Rosenberger, A; Kashofer, K; Heitzer, E; Quehenberger, F; Halbwedl, I; Graf, R; Krisper, N; Prietl, B; Höfler, G; Reinisch, A; Zebisch, A; Sill, H; Wölfler, A Sensitive and broadly applicable residual disease detection in acute myeloid leukemia using flow cytometry-based leukemic cell enrichment followed by mutational profiling.
Am J Hematol. 2020; 95(10):1148-57 Doi: 10.1002/ajh.25918 [OPEN ACCESS]
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** Dutta, S; Pregartner, G; Rücker, FG; Heitzer, E; Zebisch, A; Bullinger, L; Berghold, A; Döhner, K; Sill, H Functional Classification of TP53 Mutations in Acute Myeloid Leukemia.
Cancers (Basel). 2020; 12(3): Doi: 10.3390/cancers12030637 [OPEN ACCESS]
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** Geissler, K; Jäger, E; Barna, A; Gurbisz, M; Graf, T; Graf, E; Nösslinger, T; Pfeilstöcker, M; Machherndl-Spandl, S; Stauder, R; Zebisch, A; Sill, H; Öhler, L; Kusec, R; Hörmann, G; Valent, P Molecular Basis and Clinical Application of Growth-Factor-Independent In Vitro Myeloid Colony Formation in Chronic Myelomonocytic Leukemia.
Int J Mol Sci. 2020; 21(17): Doi: 10.3390/ijms21176057 [OPEN ACCESS]
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** Geissler, K; Jäger, E; Barna, A; Gurbisz, M; Graf, T; Graf, E; Nösslinger, T; Pfeilstöcker, M; Tüchler, H; Sliwa, T; Keil, F; Geissler, C; Heibl, S; Thaler, J; Machherndl-Spandl, S; Zach, O; Weltermann, A; Bettelheim, P; Stauder, R; Zebisch, A; Sill, H; Schwarzinger, I; Schneeweiss, B; Öhler, L; Ulsperger, E; Kusec, R; Germing, U; Sperr, WR; Knöbl, P; Jäger, U; Hörmann, G; Valent, P Correlation of RAS-Pathway Mutations and Spontaneous Myeloid Colony Growth with Progression and Transformation in Chronic Myelomonocytic Leukemia-A Retrospective Analysis in 337 Patients.
Int J Mol Sci. 2020; 21(8): Doi: 10.3390/ijms21083025 [OPEN ACCESS]
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** Hatzl, S; Perfler, B; Wurm, S; Uhl, B; Quehenberger, F; Ebner, S; Troppmair, J; Reinisch, A; Wölfler, A; Sill, H; Zebisch, A Increased Expression of Micro-RNA-23a Mediates Chemoresistance to Cytarabine in Acute Myeloid Leukemia.
Cancers (Basel). 2020; 12(2): Doi: 10.3390/cancers12020496 [OPEN ACCESS]
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** Moser, T; Waldispuehl-Geigl, J; Belic, J; Weber, S; Zhou, Q; Hasenleithner, SO; Graf, R; Terzic, JA; Posch, F; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Heitzer, E; Geigl, JB; Bauernhofer, T; Speicher, MR On-treatment measurements of circulating tumor DNA during FOLFOX therapy in patients with colorectal cancer.
NPJ Precis Oncol. 2020; 4(1):30 Doi: 10.1038/s41698-020-00134-3 [OPEN ACCESS]
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** Sill, H; Zebisch, A; Haase, D Acute Myeloid Leukemia and Myelodysplastic Syndromes with TP53 Aberrations - A Distinct Stem Cell Disorder.
Clin Cancer Res. 2020; 26(20):5304-5309 Doi: 10.1158/1078-0432.CCR-20-2272 [OPEN ACCESS]
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Kurzbericht/Letter

** Hatzl, S; Posch, F; Schulz, E; Gornicec, M; Deutsch, A; Beham-Schmid, C; Pichler, M; Greinix, H; Sill, H; Zebisch, A; Neumeister, P; Prochazka, KT The Role of Immunohistochemical Overexpression of p53 as Adverse Prognostic Factor in Primary Testicular Diffuse Large B Cell Lymphoma.
Pathol Oncol Res. 2020; 26(4):2831-2833 Doi: 10.1007/s12253-020-00864-6
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** Pabst, G; Lind, K; Graf, R; Zebisch, A; Stölzel, F; Döhner, K; Heitzer, E; Reinisch, A; Sill, H TP53 mutated AML subclones exhibit engraftment in a humanized bone marrow ossicle mouse model.
Ann Hematol. 2020; 99(3):653-655 Doi: 10.1007/s00277-020-03920-y [OPEN ACCESS]
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** Zebisch, A; Winter, G; Kashofer, K; Hatzl, S; Uhl, B; Wurm, S; Wölfler, A; Greinix, HT; Hoefler, G; Sill, H The role of germline mutation profiling in the selection of related donors for haematopoietic stem cell transplantation.
Bone Marrow Transplant. 2020; 55(7):1502-1505 Doi: 10.1038/s41409-019-0691-1 [OPEN ACCESS]
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Übersichtsarbeit

** Nguyen, CH; Grandits, AM; Purton, LE; Sill, H; Wieser, R All-trans retinoic acid in non-promyelocytic acute myeloid leukemia: driver lesion dependent effects on leukemic stem cells.
Cell Cycle. 2020; 19(20):2573-2588 Doi: 10.1080/15384101.2020.1810402 [OPEN ACCESS]
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Korrektur

** Ulz, P; Perakis, S; Zhou, Q; Moser, T; Belic, J; Lazzeri, I; Wölfler, A; Zebisch, A; Gerger, A; Pristauz, G; Petru, E; White, B; Roberts, CES; John, JS; Schimek, MG; Geigl, JB; Bauernhofer, T; Sill, H; Bock, C; Heitzer, E; Speicher, MR Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection.
Nat Commun. 2020; 11(1): 1965-1965. Doi: 10.1038/s41467-020-15799-4 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Moser, T; Waldispuehl-Geigl, J; Belic, J; Perakis, S; Weber, S; Zhou, Q; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Bauernhofer, T; Heitzer, E; Geigl, JB; Speicher, MR Early circulating tumor DNA dynamics as a real-time predictor of FOLFOX efficacy in advanced colorectal cancer patients
CANCER RES. 2020; 80(16): Doi: 10.1158/1538-7445.AM2020-4295 [Poster]
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2019

Originalarbeit (Zeitschrift)

** Aberer, F; Mader, JK; Holzgruber, J; Trummer, C; Schwetz, V; Pandis, M; Pferschy, PN; Greinix, H; Tripolt, NJ; Pieber, TR; Zebisch, A; Sill, H; Wölfler, A; Sourij, H Feasibility and safety of using an automated decision support system for insulin therapy in the treatment of steroid-induced hyperglycemia in patients with acute graft-versus-host disease: A randomized trial.
J Diabetes Investig. 2019; 10(2):339-342 Doi: 10.1111/jdi.12919 [OPEN ACCESS]
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** Aigner, P; Mizutani, T; Horvath, J; Eder, T; Heber, S; Lind, K; Just, V; Moll, HP; Yeroslaviz, A; Fischer, MJM; Kenner, L; Győrffy, B; Sill, H; Grebien, F; Moriggl, R; Casanova, E; Stoiber, D STAT3β is a tumor suppressor in acute myeloid leukemia.
Blood Adv. 2019; 3(13): 1989-2002. Doi: 10.1182/bloodadvances.2018026385 [OPEN ACCESS]
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** Daga, S; Rosenberger, A; Quehenberger, F; Krisper, N; Prietl, B; Reinisch, A; Zebisch, A; Sill, H; Wölfler, A High GPR56 surface expression correlates with a leukemic stem cell gene signature in CD34-positive AML.
Cancer Med. 2019; 8(4):1771-1778 Doi: 10.1002/cam4.2053 [OPEN ACCESS]
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** Geissler, K; Jäger, E; Barna, A; Gurbisz, M; Marschon, R; Graf, T; Graf, E; Borjan, B; Jilch, R; Geissler, C; Hoermann, G; Esterbauer, H; Schwarzinger, I; Nösslinger, T; Pfeilstöcker, M; Tüchler, H; Reisner, R; Sliwa, T; Keil, F; Bettelheim, P; Machherndl-Spandl, S; Doleschal, B; Zach, O; Weltermann, A; Heibl, S; Thaler, J; Zebisch, A; Sill, H; Stauder, R; Webersinke, G; Petzer, A; Kusec, R; Ulsperger, E; Schneeweiss, B; Berger, J; Öhler, L; Germing, U; Sperr, WR; Knöbl, P; Jäger, U; Valent, P The Austrian biodatabase for chronic myelomonocytic leukemia (ABCMML) : A representative and useful real-life data source for further biomedical research.
Wien Klin Wochenschr. 2019; 131(17-18):410-418 Doi: 10.1007/s00508-019-1526-1 [OPEN ACCESS]
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** Gluexam, T; Grandits, AM; Schlerka, A; Nguyen, CH; Etzler, J; Finkes, T; Fuchs, M; Scheid, C; Heller, G; Hackl, H; Harrer, N; Sill, H; Koller, E; Stoiber, D; Sommergruber, W; Wieser, R CGRP Signaling via CALCRL Increases Chemotherapy Resistance and Stem Cell Properties in Acute Myeloid Leukemia.
Int J Mol Sci. 2019; 20(23): Doi: 10.3390/ijms20235826 [OPEN ACCESS]
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** Prochazka, KT; Pregartner, G; Rücker, FG; Heitzer, E; Pabst, G; Wölfler, A; Zebisch, A; Berghold, A; Döhner, K; Sill, H Clinical implications of subclonal TP53 mutations in acute myeloid leukemia.
Haematologica. 2019; 104(3):516-523 Doi: 10.3324/haematol.2018.205013 [OPEN ACCESS]
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** Ulz, P; Perakis, S; Zhou, Q; Moser, T; Belic, J; Lazzeri, I; Wölfler, A; Zebisch, A; Gerger, A; Pristauz, G; Petru, E; White, B; Roberts, CES; John, JS; Schimek, MG; Geigl, JB; Bauernhofer, T; Sill, H; Bock, C; Heitzer, E; Speicher, MR Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection.
Nat Commun. 2019; 10(1): 4666-4666. Doi: 10.1038/s41467-019-12714-4 [OPEN ACCESS]
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Kurzbericht/Letter

** Bärnthaler, T; Jandl, K; Sill, H; Uhl, B; Schreiber, Y; Grill, M; Thomas, D; Schicho, R; Marsche, G; Frank, S; Heinemann, A; Schuligoi, R Imatinib stimulates prostaglandin E₂ and attenuates cytokine release via EP4 receptor activation.
J Allergy Clin Immunol. 2019; 143(2):794-797 Doi: 10.1016/j.jaci.2018.09.030 [OPEN ACCESS]
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** Müller, M; Graf, R; Kashofer, K; Macher, S; Wölfler, A; Zebisch, A; Hrzenjak, A; Heitzer, E; Sill, H Detection of AML-specific TP53 mutations in bone marrow-derived mesenchymal stromal cells cultured under hypoxia conditions.
Ann Hematol. 2019; 98(8):2019-2020 Doi: 10.1007/s00277-019-03680-4 [OPEN ACCESS]
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Übersichtsarbeit

** Zebisch, A; Caraffini, V; Sill, H RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis.
Int J Mol Sci. 2019; 20(22): Doi: 10.3390/ijms20225756 [OPEN ACCESS]
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2018

Originalarbeit (Zeitschrift)

** Blatt, K; Menzl, I; Eisenwort, G; Cerny-Reiterer, S; Herrmann, H; Herndlhofer, S; Stefanzl, G; Sadovnik, I; Berger, D; Keller, A; Hauswirth, A; Hoermann, G; Willmann, M; Rülicke, T; Sill, H; Sperr, WR; Mannhalter, C; Melo, JV; Jäger, U; Sexl, V; Valent, P Phenotyping and Target Expression Profiling of CD34⁺/CD38^- and CD34⁺/CD38⁺ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia.
Neoplasia. 2018; 20(6):632-642 Doi: 10.1016/j.neo.2018.04.004 [OPEN ACCESS]
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** Caraffini, V; Perfler, B; Berg, JL; Uhl, B; Schauer, S; Kashofer, K; Ghaffari-Tabrizi-Wizsy, N; Strobl, H; Wölfler, A; Hoefler, G; Sill, H; Zebisch, A Loss of RKIP is a frequent event in myeloid sarcoma and promotes leukemic tissue infiltration.
Blood. 2018; 131(7): 826-830. Doi: 10.1182/blood-2017-09-804906 [OPEN ACCESS]
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** Cooney, JD; Lin, AP; Jiang, D; Wang, L; Suhasini, AN; Myers, J; Qiu, Z; Wölfler, A; Sill, H; Aguiar, RCT Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies.
Clin Cancer Res. 2018; 24(5):1103-1113 Doi: 10.1158/1078-0432.CCR-17-2218 [OPEN ACCESS]
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** Gaksch, L; Kashofer, K; Heitzer, E; Quehenberger, F; Daga, S; Hofer, S; Halbwedl, I; Graf, R; Krisper, N; Hoefler, G; Zebisch, A; Sill, H; Wölfler, A Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia.
Am J Hematol. 2018; 93(1):23-30 Doi: 10.1002/ajh.24922 [OPEN ACCESS]
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** Valent, P; Stauder, R; Theurl, I; Geissler, K; Sliwa, T; Sperr, WR; Bettelheim, P; Sill, H; Pfeilstöcker, M Diagnosis, management and response criteria of iron overload in myelodysplastic syndromes (MDS): updated recommendations of the Austrian MDS platform.
Expert Rev Hematol. 2018; 11(2):109-116 Doi: 10.1080/17474086.2018.1420473
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Kurzbericht/Letter

** Kashofer, K; Gornicec, M; Lind, K; Caraffini, V; Schauer, S; Beham-Schmid, C; Wölfler, A; Hoefler, G; Sill, H; Zebisch, A Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing.
Leuk Lymphoma. 2018; 59(2):501-504 Doi: 10.1080/10428194.2017.1339879 [OPEN ACCESS]
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** Schulz, E; Lind, K; Renner, W; Petersen, BS; Quehenberger, F; Dill, C; Hofer, S; Lal, R; Hoefler, G; Schlenke, P; Ehninger, G; Schetelig, J; Middeke, JM; Stölzel, F; Sill, H The TP53 Pro72Arg SNP in de novo acute myeloid leukaemia - results of two cohort studies involving 215 patients and 3759 controls.
Br J Haematol. 2018; 181(1):148-151 Doi: 10.1111/bjh.14527 [OPEN ACCESS]
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** Unterluggauer, JJ; Prochazka, K; Tomazic, PV; Huber, HJ; Seeboeck, R; Fechter, K; Steinbauer, E; Gruber, V; Feichtinger, J; Pichler, M; Weniger, MA; Küppers, R; Sill, H; Schicho, R; Neumeister, P; Beham-Schmid, C; Deutsch, AJA; Haybaeck, J Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome.
Blood Cancer J. 2018; 8(9): 79-79. Doi: 10.1038/s41408-018-0112-5 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Hoefler, G; Geissler, K; Kolch, W; Blyth, K; Athineos, D; Wolfler, A; Sill, H; Zebisch, A Loss of RKIP expression is a frequent event in chronic myelomonocytic leukemia and functionally involved in the pathogenesis of this malignancy
ONCOL RES TREAT. 2018; 41: 27-27. [Oral Communication]
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** Daga, S; Rosenberger, A; Krisper, N; Prietl, B; Reinisch, A; Zebisch, A; Sill, H; Wolfler, A GPR56 and CLL-1 (CLEC12A) as putative leukemic stem cell markers in CD34-positive acute myeloid leukemia
ONCOL RES TREAT. 2018; 41: 73-73. [Poster]
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** Geissler, K; Barna, A; Jager, E; Gurbisz, M; Alendar, T; Ljubuncic, E; Jilch, R; Nosslinger, T; Pfeilstocker, M; Tuchler, H; Reisner, R; Sliwa, T; Keil, F; Geissler, C; Burgstaller, S; Thaler, J; Machherndl-Spandl, S; Zach, O; Weltermann, A; Bettelheim, P; Stauder, R; Borjan, B; Zebisch, A; Sill, H; Schwarzinger, I; Hormann, G; Jager, U; Sperr, WR; Knobl, P; Schneeweiss, B; Berger, J; Ohler, L; Ulsperger, E; Kusec, R; Germing, U; Valent, P The role of RAS pathway hyperactivation in the progression and transformation of chronic myelomonocytic leukemia
ONCOL RES TREAT. 2018; 41: 238-238. [Oral Communication]
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** Hatzl, S; Ebner, S; Perfler, B; Quehenberger, F; Troppmair, J; Reinisch, A; Wolfler, A; Sill, H; Zebisch, A Deregulation of the micro-RNA-23a/TOP2B axis causes resistance to cytarabine in acute myeloid leukemia
ONCOL RES TREAT. 2018; 41: 243-243. [Oral Communication]
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** Muralikrishnan, AS; Rosenberger, A; Schwarzenberger, E; Strobl, H; Zebisch, A; Sill, H; Wolfler, A A role of C/EBP alpha in early dendritic cell development
ONCOL RES TREAT. 2018; 41: 102-102. [Poster]
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** Pabst, G; Prochazka, K; Pregartner, G; Rücker, FG; Heitzer, E; Woelfler ,A; Zebisch, A; Berghold, A; Döhner, K; Sill H. Impact of TP53 mutated subclones in acute myeloid leukemia
Blood. 2018; 132(Suppl ):-Annual Meeting of the American Society of Hematology; December 1-4, 2018; San Diego. Doi: 10.1182/blood-2018-99-110667 [Poster]
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** Sill, H TP53 mutated acute myeloid leukemia
ONCOL RES TREAT. . 2018; 41: 257-257.-Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie; SEP 28-OCT 2, 2018; Vienna, AUSTRIA. [Poster]
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** Unterluggauer, JJ; Prochazka, K; Tomazic, PV; Huber, HJ; Seeboeck, R; Fechter, K; Steinbauer, E; Gruber, V; Feichtinger, J; Pichler, M; Weniger, MA; Kuppers, R; Sill, H; Schicho, R; Neumeister, P; Beham-Schmid, C; Deutsch, A; Haybaeck, J Translation initiation factors are over-expressed in aggressive lymphomas and influence their clinical course
ONCOL RES TREAT. 2018; 41: 164-164. [Poster]
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2017

Originalarbeit (Zeitschrift)

** Deutsch, AJA; Rinner, B; Pichler, M; Prochazka, K; Pansy, K; Bischof, M; Fechter, K; Hatzl, S; Feichtinger, J; Wenzl, K; Frisch, MT; Stiegelbauer, V; Prokesch, A; Krogsdam, A; Sill, H; Thallinger, GG; Greinix, HT; Wang, C; Beham-Schmid, C; Neumeister, P NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.
Cancer Res. 2017; 77(9):2375-2386 Doi: 10.1158/0008-5472.CAN-16-2320 [OPEN ACCESS]
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** Heidenreich, S; Ziagkos, D; de Wreede, LC; van Biezen, A; Finke, J; Platzbecker, U; Niederwieser, D; Einsele, H; Bethge, W; Schleuning, M; Beelen, DW; Tischer, J; Nagler, A; Glass, B; Maertens, J; Yáñez, L; Beguin, Y; Sill, H; Scheid, C; Stelljes, M; Ganser, A; Zachée, P; Selleslag, D; de Witte, T; Robin, M; Kröger, N Allogeneic Stem Cell Transplantation for Patients Age ≥ 70 Years with Myelodysplastic Syndrome: A Retrospective Study of the MDS Subcommittee of the Chronic Malignancies Working Party of the EBMT.
Biol Blood Marrow Transplant. 2017; 23(1):44-52 Doi: 10.1016/j.bbmt.2016.09.027 [OPEN ACCESS]
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** Lal, R; Lind, K; Heitzer, E; Ulz, P; Aubell, K; Kashofer, K; Middeke, JM; Thiede, C; Schulz, E; Rosenberger, A; Hofer, S; Feilhauer, B; Rinner, B; Svendova, V; Schimek, MG; Rücker, FG; Hoefler, G; Döhner, K; Zebisch, A; Wölfler, A; Sill, H Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia.
Blood. 2017; 129(18): 2587-2591. Doi: 10.1182/blood-2016-11-751008 [OPEN ACCESS]
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** Magina, KN; Pregartner, G; Zebisch, A; Wölfler, A; Neumeister, P; Greinix, HT; Berghold, A; Sill, H Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis.
Blood. 2017; 130(7): 946-948. Doi: 10.1182/blood-2017-04-777722 [OPEN ACCESS]
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** Peschel, I; Podmirseg, SR; Taschler, M; Duyster, J; Götze, KS; Sill, H; Nachbaur, D; Jäkel, H; Hengst, L FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27^Kip1 in acute myeloid leukemia.
Haematologica. 2017; 102(8):1378-1389 Doi: 10.3324/haematol.2016.160101 [OPEN ACCESS]
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** Pleyer, L; Döhner, H; Dombret, H; Seymour, JF; Schuh, AC; Beach, CL; Swern, AS; Burgstaller, S; Stauder, R; Girschikofsky, M; Sill, H; Schlick, K; Thaler, J; Halter, B; Machherndl Spandl, S; Zebisch, A; Pichler, A; Pfeilstöcker, M; Autzinger, EM; Lang, A; Geissler, K; Voskova, D; Sperr, WR; Hojas, S; Rogulj, IM; Andel, J; Greil, R Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group.
Int J Mol Sci. 2017; 18(2): Doi: 10.3390/ijms18020415 [OPEN ACCESS]
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** Stauber, MN; Aberer, F; Oulhaj, A; Mader, JK; Zebisch, A; Pieber, TR; Neumeister, P; Greinix, HT; Sill, H; Sourij, H; Wölfler, A Early Hyperglycemia after Initiation of Glucocorticoid Therapy Predicts Adverse Outcome in Patients with Acute Graft-versus-Host Disease.
Biol Blood Marrow Transplant. 2017; 23(7):1186-1192 Doi: 10.1016/j.bbmt.2017.03.010 [OPEN ACCESS]
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** Stefanzl, G; Berger, D; Cerny-Reiterer, S; Blatt, K; Eisenwort, G; Sperr, WR; Hoermann, G; Lind, K; Hauswirth, AW; Bettelheim, P; Sill, H; Melo, JV; Jager, U; Valent, P The pan-BCL-2-blocker obatoclax (GX15-070) and the PI3-kinase/mTOR-inhibitor BEZ235 produce cooperative growth-inhibitory effects in ALL cells
ONCOTARGET. 2017; 8(40): 67709-67722. Doi: 10.18632/oncotarget.18810 [OPEN ACCESS]
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Kurzbericht/Letter

** Aberer, F; Kremser, S; Mader, JK; Zinke-Cerwenka, W; Greinix, H; Tripolt, NJ; Pieber, TR; Zebisch, A; Sill, H; Oulhaj, A; Sourij, H; Wölfler, A Hyperglycaemia within the first month after allogeneic haematopoietic stem-cell transplantation is an independent risk factor for overall survival in patients with acute myeloid leukaemia.
Diabetes Metab. 2017; 43(6):560-562 Doi: 10.1016/j.diabet.2017.02.001
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** Elkashef, SM; Lin, AP; Myers, J; Sill, H; Jiang, D; Dahia, PLM; Aguiar, RCT IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation.
Cancer Cell. 2017; 31(5): 619-620. Doi: 10.1016/j.ccell.2017.04.001 [OPEN ACCESS]
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** Gornicec, M; Wölfler, A; Stanzel, S; Sill, H; Zebisch, A Evidence for a role of decitabine in the treatment of myeloid sarcoma.
Ann Hematol. 2017; 96(3):505-506 Doi: 10.1007/s00277-016-2870-0 (- Case Report) [OPEN ACCESS]
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** Schulz, E; Sill, H The TP53 Pro72Arg SNP in de novo acute myeloid leukemia.
Haematologica. 2017; 102(5): e214-e215-e214-e215. Doi: 10.3324/haematol.2017.165019 [OPEN ACCESS]
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** Spindelboeck, W; Schulz, E; Uhl, B; Kashofer, K; Aigelsreiter, A; Zinke-Cerwenka, W; Mulabecirovic, A; Kump, PK; Halwachs, B; Gorkiewicz, G; Sill, H; Greinix, H; Högenauer, C; Neumeister, P Repeated fecal microbiota transplantations attenuate diarrhea and lead to sustained changes in the fecal microbiota in acute, refractory gastrointestinal graft-versus-host-disease.
Haematologica. 2017; 102(5):e210-e213-e210-e213 Doi: 10.3324/haematol.2016.154351 (- Case Report) [OPEN ACCESS]
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Abstract (Zeitschrift)

** Aberer, F; Holzgruber, J; Tripolt, NJ; Zebisch, A; Greinix, H; Sill, H; Mader, JK; Pieber, TR; Wölfler, A; Sourij, H Efficacy and safety of an insulin decision support system in the treatment of steroid hyperglycaemia in patients with graft-versus- host-disease: a randomised pilot trial.
Diabetologia. 2017; 60(S1):S323-S324.-53rd Annual Meeting of the European Association for the Study of Diabetes (EASD); SEP 11-15, 2017; Lisbon, PORTUGAL. [Poster]
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** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Hoefler, G; Geissler, K; Kolch, W; Blyth, K; Athineos, D; Woelfler, A; Sill, H; Zebisch, A LOSS OF RAF KINASE INHIBITOR PROTEIN IS INVOLVED IN MYELOMONOCYTIC LINEAGE COMMITMENT AND AGGRAVATES THE DEVELOPMENT OF CHRONIC MYELOMONOCYTIC LEUKEMIA IN A MURINE IN-VIVO MODEL
HAEMATOLOGICA. 2017; 102: 148-149.-22nd Congress of the European-Hematology-Association; JUN 22-25, 2017; Madrid, SPAIN. [Oral Communication]
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** Caraffini, V; Schauer, S; Kashofer, K; Wolfler, A; Hoefler, G; Sill, H; Zebisch, A RAF KINASE INHIBITOR PROTEIN IS INVOLVED IN THE DEVELOPMENT OF MYELOID SARCOMA
HAEMATOLOGICA. 2017; 102: 361-362.-22nd Congress of the European-Hematology-Association; JUN 22-25, 2017; Madrid, SPAIN. [Poster]
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** Gaksch, L; Kashofer, K; Heitzer, E; Daga, S; Hofer, S; Krisper, N; Hofler, G; Zebisch, A; Sill, H; Wolfler, A Persistence of non-DNMT3A mutations predicts relapse in cytogenetically normal AML
ONCOL RES TREAT. 2017; 40: 140-141. [Oral Communication]
Web of Science

 

** Geissler, K; Barna, A; Jäger, E; Alendar, T; Ljubuncic, E; Jilch, R; Nösslinger, T; Pfeilstöcker, M; Tüchler, H; Reisner, R; Sliwa, T; Keil, F; Burgstaller, S; Thaler, J; Machherndl-Spandl, S; Zach, O; Weltermann, A; Bettelheim, P; Stauder, R; Schwarzinger, I; Hörmann, G; Jäger, U; Sperr, RW; Knöbl, P; Schneeweiss, B; Berger, J; Kusec, R; Öhler, L; Zebisch, A; Sill, H; Germing, U; Valent, P High spontaneous in-vitro myeloid colony growth is an adverse risk factor in chronic myelomonocytic leukemia
Oncol Res Treat. 2017; 40(S3):131-131.-Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie; SEP 29 - OCT 3, 2017; Stuttgart, GERMANY. (ISBN: 978-3-318-06110-9 ) [Oral Communication]
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** Neumeister, P; Spindelboeck, W; Zinke-Cerwenka, W; Schulz, E; Hoegenauer, C; Sill, H; Gorkiewicz, G; Kump, P; Greinix, H Successful treatment of steroid-refractory acute gastrointestinal graft-versus-host-disease by fecal microbiota transplantation
BONE MARROW TRANSPL. 2017; 52: S232-S232.
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** Nomdedeu, M; Tuechler, H; Kuendgen, A; Sole, F; Schanz, J; Hildebrandt, B; Grau, J; Pereira, A; Garcia-Manero, G; Sekeres, MA; Komrokji, RS; Voso, MT; List, AF; Cazzola, M; Sill, H; Stauder, R; Greenberg, P; Germing, U; Sanz, G; Haase, D CHROMOSOMAL ABERRATIONS IN THERAPY-RELATED MYELODYSPLASTIC SYNDROMES - RELATIONS TO PRIMARY DISEASE, THERAPY AND PROGNOSTIC SIGNIFICANCE
LEUKEMIA RES. .. 2017; 55: S32-S33.-14th International Symposium on Myelodysplastic Syndromes (MDS); MAY 03-06, 2017; Valencia, SPAIN. Doi: 10.1016/S0145-2126(17)30161-3 [Poster]
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** Stauber, M; Aberer, F; Oulhaj, A; Mader, JK; Zebisch, A; Pieber, TR; Neumeister, P; Greinix, HT; Sill, H; Sourij, H; Wolfler, A Early hyperglycaemia after initiation of glucocorticoid therapy predicts adverse outcome in patients with acute graft-versus-host disease
BONE MARROW TRANSPL. 2017; 52: S285-S285.
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** Unterluggauer, J; Beham-Schmid, C; Tomazic, PV; Fechter, K; Rinner, B; Pichler, M; Weniger, M; Kuppers, R; Sill, H; Schicho, R; Neumeister, P; Deutsch, A; Haybaeck, J Translation initiation factors as novel prognostic biomarkers of aggressive B-cell lymphomas
VIRCHOWS ARCH. 2017; 471: S43-S43. [Poster]
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2016

Originalarbeit (Zeitschrift)

** Bainschab, A; Quehenberger, F; Greinix, HT; Krause, R; Wölfler, A; Sill, H; Zebisch, A Infections in patients with acute myeloid leukemia treated with low-intensity therapeutic regimens: Risk factors and efficacy of antibiotic prophylaxis.
Leuk Res. 2016; 42(3):47-51 Doi: 10.1016/j.leukres.2016.01.014
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** Hatzl, S; Geiger, O; Kuepper, MK; Caraffini, V; Seime, T; Furlan, T; Nussbaumer, E; Wieser, R; Pichler, M; Scheideler, M; Nowek, K; Jongen-Lavrencic, M; Quehenberger, F; Wölfler, A; Troppmair, J; Sill, H; Zebisch, A Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.
Cancer Res. 2016; 76(12):3644-3654 Doi: 10.1158/0008-5472.CAN-15-3049 [OPEN ACCESS]
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** Pleyer, L; Burgstaller, S; Stauder, R; Girschikofsky, M; Sill, H; Schlick, K; Thaler, J; Halter, B; Machherndl-Spandl, S; Zebisch, A; Pichler, A; Pfeilstöcker, M; Autzinger, EM; Lang, A; Geissler, K; Voskova, D; Geissler, D; Sperr, WR; Hojas, S; Rogulj, IM; Andel, J; Greil, R Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications.
J Hematol Oncol. 2016; 9(6):39-39 Doi: 10.1186/s13045-016-0263-4 [OPEN ACCESS]
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** Sadovnik, I; Hoelbl-Kovacic, A; Herrmann, H; Eisenwort, G; Cerny-Reiterer, S; Warsch, W; Hoermann, G; Greiner, G; Blatt, K; Peter, B; Stefanzl, G; Berger, D; Bilban, M; Herndlhofer, S; Sill, H; Sperr, WR; Streubel, B; Mannhalter, C; Holyoake, TL; Sexl, V; Valent, P Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.
Clin Cancer Res. 2016; 22(8):2051-2061 Doi: 10.1158/1078-0432.CCR-15-0767 [OPEN ACCESS]
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** Zebisch, A; Lal, R; Müller, M; Lind, K; Kashofer, K; Girschikofsky, M; Fuchs, D; Wölfler, A; Geigl, JB; Sill, H Acute myeloid leukemia with TP53 germ line mutations.
Blood. 2016; 128(18): 2270-2272. Doi: 10.1182/blood-2016-08-732610 [OPEN ACCESS]
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Kurzbericht/Letter

** Sill, H; Kqiku-Kryeziu, X; Avian, A; Kovacs, G; Gaal, S; Zebisch, A; Olschewski, H Pulmonary arterial pressure in patients with myelodysplastic syndromes.
Leuk Lymphoma. 2016; 57(11):2723-2726 Doi: 10.3109/10428194.2016.1160086
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Übersichtsarbeit

** Zebisch, A; Hatzl, S; Pichler, M; Wölfler, A; Sill, H Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs.
Int J Mol Sci. 2016; 17(12): Doi: 10.3390/ijms17122080 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Gaksch, L; Kashofer, K; Heitzer, E; Daga, S; Hofer, S; Krisper, N; Höfler, G; Zebisch, A; Sill, H; Wölfler A Persitence of non-DNMT3A mutations predicts relapse in cytogenetically normal AML.
Oncol Res Treat 2016. 2016; 39(suppl3):140--Jahrestagung DGHO; OCT 14-18,2016; Leipzig. (ISBN: 2296-5270 ) [Oral Communication]
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** Heidenreich, S; Ziagkos, D; van Biezen, A; Finke, J; Platzbecker, U; Niederwieser, D; Einsele, H; Bethge, WA; Schleuning, M; Beelen, DW; Tischer, J; Nagler, A; Glass, B; Maertens, J; Richard, C; Beguin, Y; Sill, H; de Witte, T; Robin, M; Kroger, N Allogeneic Stem Cell Transplantation for MDS Patients More Than 70 Years of Age: Update of a Retrospective Study of the MDS Subcommittee of the Chronic Malignancies Working Party (CMWP) of the EBMT
BONE MARROW TRANSPL. 2016; 51: S510-S511.-42nd Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation; APR 03-06, 2016; Valencia, SPAIN. [Oral Communication]
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** Magina, N; Pregartner, G; Berghold, A; Sill, H Conventional post-remission therapy in adult acute myeloid leukemia - a systematic review/meta-analysis
WIEN KLIN WOCHENSCHR. 2016; 128: S385-S385. [Poster]
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** Olipitz, W; Lind, K; Monsberger, N; Katschnig, A; Mangerich, A; Rankl, J; Hofer, S; Mueller, M; Schulz, E; Quehenberger, F; Schlembach, D; Robier, C; Woelfler, A; Zebisch, A; Sill, H IMPAIRED BASE EXCISION REPAIR GLYCOSYLASE/AP ENDONUCLEASE ACTIVITY CONTRIBUTES TO CYTARABINE RESISTANCE IN ACUTE MYELOID LEUKEMIA
HAEMATOLOGICA. 2016; 101: 211-212. [Poster]
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** Schulz, E; Lind, K; Renner, W; Petersen, BS; Dill, C; Hofer, S; Lal, R; Quehenberger, F; Stolzel, F; Sill, H THE HOMOZYGOUS TP53 P72R SNP IS ASSOCIATED WITH NON-FAVORABLE CYTOGENETIC RISK GROUPS IN ACUTE MYELOID LEUKEMIA
HAEMATOLOGICA. 2016; 101: 383-383. [Poster]
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** Zebisch, A; Lal, R; Muller, M; Lind, K; Sill, H TP53 germline mutations occur in acute myeloid leukemia and are associated with therapy-related cases following ionizing radiation
WIEN KLIN WOCHENSCHR. 2016; 128: S385-S386. [Poster]
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Kommentar

** Sill, H; Schulz, E; Steinke-Lange, V; Boland, CR Correspondence: Reply to 'SEMA4A variation and risk of colorectal cancer'.
Nat Commun. 2016; 7:10695-10695 Doi: 10.1038/ncomms10695 [OPEN ACCESS]
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2015

Originalarbeit (Zeitschrift)

** Burgstaller, S; Bettelheim, P; Krieger, O; Machherndl-Spandl, S; Nösslinger, T; Pleyer, L; Sill, H; Sperr, WR; Stauder, R; Valent, P; Pfeilstöcker, M 10th anniversary of the Austrian MDS Platform: aims and ongoing projects.
Wien Klin Wochenschr. 2015; 127(1-2):12-15 Doi: 10.1007/s00508-014-0627-0
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** Cerny-Reiterer, S; Rabenhorst, A; Stefanzl, G; Herndlhofer, S; Hoermann, G; Müllauer, L; Baumgartner, S; Beham-Schmid, C; Sperr, WR; Mannhalter, C; Sill, H; Linkesch, W; Arock, M; Hartmann, K; Valent, P Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia.
Oncotarget. 2015; 6(5):3071-3084 Doi: 10.18632/oncotarget.3074 [OPEN ACCESS]
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** Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819 Doi: 10.1002/mc.22252 [OPEN ACCESS]
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** Leitner, E; Zarfel, G; Luxner, J; Herzog, K; Pekard-Amenitsch, S; Hoenigl, M; Valentin, T; Feierl, G; Grisold, AJ; Högenauer, C; Sill, H; Krause, R; Zollner-Schwetz, I Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward.
Antimicrob Agents Chemother. 2015; 59(1):714-716 Doi: 10.1128/AAC.04306-14 [OPEN ACCESS]
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** Lin, AP; Abbas, S; Kim, SW; Ortega, M; Bouamar, H; Escobedo, Y; Varadarajan, P; Qin, Y; Sudderth, J; Schulz, E; Deutsch, A; Mohan, S; Ulz, P; Neumeister, P; Rakheja, D; Gao, X; Hinck, A; Weintraub, ST; DeBerardinis, RJ; Sill, H; Dahia, PL; Aguiar, RC D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2.
Nat Commun. 2015; 6(7):7768-7768 Doi: 10.1038/ncomms8768 [OPEN ACCESS]
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** Ortega, M; Bhatnagar, H; Lin, AP; Wang, L; Aster, JC; Sill, H; Aguiar, RC A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies.
Leukemia. 2015; 29(4):968-976 Doi: 10.1038/leu.2014.302 [OPEN ACCESS]
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Kurzbericht/Letter

** Geiger, O; Hatzl, S; Kashofer, K; Hoefler, G; Wölfler, A; Sill, H; Zebisch, A Deletion of SPRY4 is a frequent event in secondary acute myeloid leukemia.
Ann Hematol. 2015; 94(11):1923-1924 Doi: 10.1007/s00277-015-2445-5 [OPEN ACCESS]
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** Hackl, H; Steinleitner, K; Lind, K; Hofer, S; Tosic, N; Pavlovic, S; Suvajdzic, N; Sill, H; Wieser, R A gene expression profile associated with relapse of cytogenetically normal acute myeloid leukemia is enriched for leukemia stem cell genes.
Leuk Lymphoma. 2015; 56(4):1126-1128 Doi: 10.3109/10428194.2014.944523 [OPEN ACCESS]
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** Schulz, E; Kashofer, K; Heitzer, E; Mhatre, KN; Speicher, MR; Hoefler, G; Sill, H Preexisting TP53 mutation in therapy-related acute myeloid leukemia.
Ann Hematol. 2015; 94(3):527-529 Doi: 10.1007/s00277-014-2191-0 (- Case Report) [OPEN ACCESS]
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** Zebisch, A; Schulz, E; Grosso, M; Lombardo, B; Acierno, G; Sill, H; Iolascon, A Identification of a novel variant of epsilon-gamma-delta-beta thalassemia highlights limitations of next generation sequencing.
Am J Hematol. 2015; 90(3): E52-E54. Doi: 10.1002/ajh.23913 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Aberer, F; Mader, JK; Kremser, S; Zinke-Cerwenka, W; Greinix, H; Pieber, TR; Zebisch, A; Sill, H; Oulhaj, A; Wölfler, A; Sourij, H Glykämie nach allogener Stammzelltransplantation bei Patienten mit akuter myeloischer Leukämie (AML) ist ein unabhängiger Prädiktor für das Überleben.
Wiener Klinische Wochenschrift. 2015; 127(Suppl 4 ):S135-S135.-43. Jahrestagung der Österreichischen Diabetes Gesellschaft (ÖDG); NOV 19-21, 2015; Salzburg, AUSTRIA. [Poster]
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** Bainschab, A; Quehenberger, F; Greinix, HT; Krause, R; Wolfler, A; Sill, H; Zebisch, A Efficacy of antibiotic prophylaxis in AML patients treated with low-intensity therapeutic regimens
ONCOL RES TREAT. 2015; 38: 73-74. [Poster]
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** Hatzl, S; Geiger, O; Kuepper, MK; Seime, T; Nussbaumer, E; Wieser, R; Pichler, M; Scheideler, M; Nowek, K; Jongen-Lavrencic, M; Wolfler, A; Troppmair, J; Sill, H; Zebisch, A Loss of the tumor- and metastasis suppressor RAF kinase inhibitor protein is caused by the overexpression of miRNA-23a
ONCOL RES TREAT. 2015; 38: 99-99. [Oral Communication]
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** Heidenreich, S; Ziagkos, D; van Biezen, A; Finke, J; Platzbecker, U; Niederwieser, D; Einsele, H; Bethge, WA; Schleuning, M; Beelen, DW; Tischer, J; Nagler, A; Class, B; Maertens, J; Richard, C; Beguin, Y; Sill, H; de Witte, T; Robin, M; Kroeger, N Allogeneic Stem Cell Transplantation for MDS Patients More Than 70 Years of Age: a Retrospective Study of the MDS Subcommittee of the Chronic Malignancies Working Party (CMWP) of the EBMT
BLOOD. 2015; 126(23):-55th Annual Meeting and Exposition of the American-Society-of-Hematology; DEC 07-10, 2013; New Orleans, LA. [Oral Communication]
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** Pleyer, L; Burgstaller, S; Stauder, R; Girschikofsky, M; Sill, H; Schlick, K; Thaler, J; Halter, B; Machherndl-Spandl, S; Zebisch, A; Pichler, A; Pfeilstöcker, M; Autzinger, EM; Lang, A; Geissler, K; Voskova, D; Geissler, D; Sperr, WR; Hojas, S; Mandac-Rogulj, I; Andel, J; Greil, R Is it time to redefine response or treatment failure in elderly patients with WHO-AML unfit for intensive chemotherapy?
Blood 2015. 2015; 126(23):-Annual meeting of the American Society of Hematology; DEC 5-8, 2015; Orlando, USA. [Poster]
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** Pleyer, L; Burgstaller, S; Stauder, R; Girschikofsky, M; Sill, H; Schlick, K; Thaler, J; Halter, B; Machherndl-Spandl, S; Zebisch, A; Pichler, A; Pfeilstöcker, M; Autzinger, EM; Lang, A; Geissler, K; Voskova, D; Geissler, D; Sperr, WR; Hojas, S; Mandac-Rogulj, I; Andel, J; Greil, R Azacitidine in acute myeloid leukemia with >30% bone marrow blasts and <15 G/L white blood cell count: Results from the Austrian Azacitidine Registry of the AGMT Study Group versus randomized controlled phase III clinical trial data.
Blood 2015. 2015; 126(23):-Annual Meeting of the American Society of Hematology; DEC 5-8, 2015; Orlando, USA. [Poster]
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** Rosenberger, A; Geiger, O; Zebisch, A; Sill, H; Wolfler, A C/EBP alpha-induced proinflammatory cytokines regulate early dendritic cell development
ONCOL RES TREAT. 2015; 38: 249-250. [Poster]
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** Stauber, M; Aberer, F; Zebisch, A; Neumeister, P; Greinix, HT; Sill, H; Sourij, H; Wolfler, A Steroid-induced hyperglycemia adversely impacts outcome in graft-versus-host disease
ONCOL RES TREAT. 2015; 38: 129-129. [Poster]
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** Vilits, T; Huber-Krassnitzer, B; Zinke-Cerwenka, W; Neumeister, P; Quehenberger, F; Hoenigl, M; Sill, H; Woffler, A Impact of linezolid on hematopoietic engraftment in patients after umbilical cord blood stem cell transplantation
BONE MARROW TRANSPL. 2015; 50: S192-S192.-41st Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation; MAR 22-25, 2015; Istanbul, TURKEY. [Poster]
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2014

Originalarbeit (Zeitschrift)

** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Nojima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Heitzer, E; Geigl, JB; Windpassinger, C; Hoefler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Nat Commun. 2014; 5(10):5191-5191 Doi: 10.1038/ncomms6191 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Olipitz, W; Lind, K; Monsberger, N; Katschnig, A; Mangerich, A; Hofer, S; Schulz, E; Quehenberger, F; Schlembach, D; Robier, C; Woelfler, A; Zebisch, A; Sill, H Base Excision Repair Glycosylase Activity Is Impaired in a Subgroup of Acute Myeloid Leukemia Resulting in Increased Levels of Oxidative Base Lesions
BLOOD. 2014; 124(21):-56th Annual Meeting of the American-Society-of-Hematology; DEC 06-09, 2014; San Francisco, CA. [Poster]
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** Olipitz, W; Lind, K; Monsberger, N; Katschnig, A; Mangerich, A; Hofer, S; Schulz, E; Quehenberger, F; Schlembach, D; Robier, C; Wölfler, A; Zebisch, A; Sill, H Base excision repair glycosylase activity is impaired in a subgroup of acute myeloid leukemia resulting in increased levels of oxidative base lesions
Oncol Res Treat. 2014; 37(S5):49-49.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 10-14; Hamburg, GERMANY. (ISBN: 978-3-318-02811-9 ) [Poster]
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** Sadovnik, I; Herrmann, H; Stefanzl, G; Berger, D; Hoermann, G; Blatt, K; Cerny-Reiterer, S; Sperr, WR; Sill, H; Valent, P EFFECTS OF THE PI3-KINASE/MTOR INHIBITOR BEZ235 ON ONCOGENIC SIGNALING, PROLIFERATION AND SURVIVAL OF LEUKEMIC CELLS IN CML
HAEMATOLOGICA. 2014; 99: 67-67.-19th Congress of the European-Hematology-Association; JUN 12-15, 2014; Milan, ITALY. [Poster]
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** Sadovnik, I; Herrmann, H; Stefanzl, G; Berger, D; Hoermann, G; Blatt, K; Cerny-Reiterer, S; Sperr, WR; Sill, H; Valent, P The PI3K/mTOR blocker BEZ235 and BCR/ABL TKIs exert synergistic growth-inhibitory effects in CML cells
ONCOL RES TREAT. 2014; 37: 56-56. [Poster]
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** Schmidt, S; Sill, H; Greil, R; Burgstaller, S; Schlogl, E; Petzer, A UPDATED REPORT OF THE AUSTRIAN CML REGISTRY
HAEMATOLOGICA. 2014; 99: 341-341.-19th Congress of the European-Hematology-Association; JUN 12-15, 2014; Milan, ITALY. [Poster]
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** Schmidt, S; Sill, H; Greil, R; Burgstaller, S; Sliwa, T; Petzer, A; Lang, A; Weltermann, A; Voskova, D; Mitterer, M; Valent, P; Eberhard, N; Walder, A; Geissler, K; Andel, J; Hausler, C; Ludescher, C; Oexle, H; Korger, M; Schnallinger, M; Schreieck, S; Krippl, P; Pober, M; Woell, E; Geissler, D; Rochau, U; Siebert, U; Thaler, J; Gastl, G Updated report of the Austrian CML registry
ONCOL RES TREAT. 2014; 37: 57-58. [Poster]
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** Schulz, E; Kashofer, K; Mhatre, KN; Höfler, G; Sill, H SELECTION OF A PRE-EXISTING TP53 MUTATED CLONE IN THERAPY-RELATED ACUTE MYELOID LEUKEMIA
Haematologica. 2014; 99(S1):15-15.-19th Congress of the European Hematology Association; JUNE 12-15, 2014; Milan, ITALY. [Poster]
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** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Najima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Geigl, JB; Höfler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the semaphorin SEMA4A confer susceptibility to familial colorectal cancer type X
Oncol Res Treat. 2014; 37(S5):105-105.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 10-14, 2014; Hamburg, GERMANY. (ISBN: 978-3-318-02811-9 ) [Oral Communication]
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** Wölfler, A; Rosenberger, A; Wolf, O; Zebisch, A; Touw, IP; Sill, H A role of C/EBP-Alpha in Development of Plasmacytoid Dendritic Cells in the Thymus
Haematologica. 2014; 99(S1):174-174.-19th Congress of European Hematology Association; JUN 12-15, 2014; Milan, ITALY. [Poster]
Web of Science

 

** Zebisch, A; Wolf, O; Rosenberger, A; Petricevic, P; Hatzl, S; Troppmair, J; Kolch, W; Blyth, K; Haller, M; Sill, H; Woelfler, A RAF kinase inhibitor protein is involved in the regulation of myelomonocytic differentiation.
Oncol Res Treat. 2014; 37(S5):49-49. 2014; 37(S5):24-24.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 10-14; Hamburg. (ISBN: 978-3-318-0281 ) [Oral Communication]
Web of Science

 

Kommentar

** Neumeister, P; Sill, H Novel face of microRNA-155.
Blood. 2014; 123(1):5-7 Doi: 10.1182/blood-2013-11-534107 [OPEN ACCESS]
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2013

Originalarbeit (Zeitschrift)

** Heitzer, E; Auer, M; Gasch, C; Pichler, M; Ulz, P; Hoffmann, EM; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Lackner, C; Höfler, G; Eisner, F; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.
Cancer Res. 2013; 73(10):2965-2975 Doi: 10.1158/0008-5472.CAN-12-4140 [OPEN ACCESS]
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** Heitzer, E; Auer, M; Hoffmann, EM; Pichler, M; Gasch, C; Ulz, P; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Mohan, S; Pristauz, G; Lackner, C; Höfler, G; Eisner, F; Petru, E; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer.
Int J Cancer. 2013; 133(2):346-356 Doi: 10.1002/ijc.28030 [OPEN ACCESS]
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** Rommer, A; Steinleitner, K; Hackl, H; Schneckenleithner, C; Engelmann, M; Scheideler, M; Vlatkovic, I; Kralovics, R; Cerny-Reiterer, S; Valent, P; Sill, H; Wieser, R Overexpression of primary microRNA 221/222 in acute myeloid leukemia.
BMC Cancer. 2013; 13(8):364-364 Doi: 10.1186/1471-2407-13-364 [OPEN ACCESS]
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Kurzbericht/Letter

** Orendi, K; Emberger, W; Speicher, MR; Hoefler, G; Sill, H Molecular Cytogenetics and Multiplex Reverse-Transcriptase Polymerase Chain Reaction for Risk Stratification in Acute Myeloid Leukemia.
J Clin Oncol. 2013; 31(18):2360-2361 Doi: 10.1200/JCO.2013.48.8189 [OPEN ACCESS]
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** Zebisch, A; Hoefler, G; Quehenberger, F; Wölfler, A; Sill, H Mutant DNMT3A in acute myeloid leukemia: guilty of inducing genetic instability?
Leukemia. 2013; 27(8): 1777-1778. Doi: 10.1038/leu.2013.48 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Cerny-Reiterer, S; Herrmann, H; Blatt, K; Sadovnik, I; Eisenwort, G; Mitterbauer-Hohendanner, G; Mannhalter, C; Hauswirth, A; Sperr, WR; Sill, H; Jager, U; Valent, P Phenotype and Target Expression Profiles of Leukemic Stem Cells in Ph plus and Ph- Acute Lymphoblastic Leukemia (ALL)
ONKOLOGIE. . 2013; 36: 182-183. [Poster]
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** Hoenigl, M; Koidl, C; Duettmann, W; Huber-Krassnitzer, B; Waitzl, B; Neumeister, P; Posch, V; Seeber, K; Wagner, J; Sill, H; Wolfler, A; Krause, R; Serum and urine galactomannan testing for screening in patients with hematological malignancies.
MYCOSES. 2013; 56: 85-85.-6th Trends in Medical Mycology; OCT 11-14, 2013; Kopenhagen, DENMARK.
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2012

Originalarbeit (Zeitschrift)

** Fried, I; Bodner, C; Pichler, MM; Lind, K; Beham-Schmid, C; Quehenberger, F; Sperr, WR; Linkesch, W; Sill, H; Wölfler, A Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia.
Haematologica. 2012; 97(2):246-250 Doi: 10.3324/haematol.2011.051581 [OPEN ACCESS]
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** Hoenigl, M; Raggam, RB; Salzer, HJ; Valentin, T; Valentin, A; Zollner-Schwetz, I; Strohmeier, AT; Seeber, K; Wölfler, A; Sill, H; Krause, R Posaconazole plasma concentrations and invasive mould infections in patients with haematological malignancies.
Int J Antimicrob Agents. 2012; 39(6):510-513 Doi: 10.1016/j.ijantimicag.2012.02.002
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** Schulz, E; Valentin, A; Ulz, P; Beham-Schmid, C; Lind, K; Rupp, V; Lackner, H; Wölfler, A; Zebisch, A; Olipitz, W; Geigl, J; Berghold, A; Speicher, MR; Sill, H Germline mutations in the DNA damage response genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy related myeloid neoplasms.
J Med Genet. 2012; 49(7):422-428 Doi: 10.1136/jmedgenet-2011-100674
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** Zebisch, A; Wölfler, A; Fried, I; Wolf, O; Lind, K; Bodner, C; Haller, M; Drasche, A; Pirkebner, D; Matallanas, D; Rath, O; Blyth, K; Delwel, R; Taskesen, E; Quehenberger, F; Kolch, W; Troppmair, J; Sill, H Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia.
Leukemia. 2012; 26(8):1842-1849 Doi: 10.1038/leu.2012.61 [OPEN ACCESS]
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Kurzbericht/Letter

** Fried, I; Wölfler, A; Quehenberger, F; Hoefler, G; Sill, H; Zebisch, A Mutations inDNMT3A and loss of RKIP are independent events in acute monocytic leukemia.
Haematologica. 2012; 97(12):1936-1937 Doi: 10.3324/haematol.2012.068429 [OPEN ACCESS]
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** Rankl, J; Flicker, K; Valentin, A; Horn, M; Uranus, S; Groselj-Strele, A; Emberger, W; Sill, H; Hypersensitivity to alkylation treatment of primary fibroblasts from patients with therapy-related myeloid neoplasms.
Leuk Res. 2012; 36(7):e137-e139 Doi: 10.1016/j.leukres.2012.03.005
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Abstract (Zeitschrift)

** Schulz, E; Valentin, A; Ulz, P; Beham-Schmid, C; Lind, K; Rupp, V; Lackner, H; Wolfler, A; Zebisch, A; Olipitz, W; Geigl, JB; Berghold, A; Speicher, MR; Sill, H Germ-line mutations in cancer predisposing genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy-related myeloid neoplasms.
ONKOLOGIE. Onkologie. 2012; 35: 117-117.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 19-23, 2012; Stuttgart, GERMANY. [Poster]
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2011

Originalarbeit (Zeitschrift)

** Hoenigl, M; Zollner-Schwetz, I; Sill, H; Linkesch, W; Lass-Flörl, C; Schnedl, WJ; Krause, R Epidemiology of invasive fungal infections and rationale for antifungal therapy in patients with haematological malignancies.
Mycoses. 2011; 54(5):454-459 Doi: 10.1111/j.1439-0507.2010.01881.x
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** Robier, C; Neubauer, M; Beham-Schmid, C; Sill, H Thrombotic microangiopathy and disseminated intravascular coagulation associated with carcinocythemia in a patient with breast cancer.
J CLIN ONCOL. 2011; 29(34): e825-e826. Doi: 10.1200/JCO.2011.36.7433 (- Case Report) [OPEN ACCESS]
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** Zinke-Cerwenka, W; Valentin, A; Posch, U; Beham-Schmid, C; Groselj-Strele, A; Linkesch, W; Wölfler, A; Sill, H Reduced-intensity allografting in patients with therapy-related myeloid neoplasms and active primary malignancies.
Bone Marrow Transplant. 2011; 46(12):1540-1544 Doi: 10.1038/bmt.2011.165 [OPEN ACCESS]
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Kurzbericht/Letter

** Pichler, MM; Bodner, C; Fischer, C; Deutsch, AJ; Hiden, K; Beham-Schmid, C; Linkesch, W; Guelly, C; Sill, H; Wölfler, A Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy.
Br J Haematol. 2011; 152(5): 669-672. Doi: 10.1111/j.1365-2141.2010.08404.x [OPEN ACCESS]
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Übersichtsarbeit

** Sill, H; Olipitz, W; Zebisch, A; Schulz, E; Wölfler, A Therapy-related myeloid neoplasms: pathobiology and clinical characteristics.
Br J Pharmacol. 2011; 162(4): 792-805. Doi: 10.1111/j.1476-5381.2010.01100.x [OPEN ACCESS]
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Abstract (Zeitschrift)

** Kqiku, X; Kovacs, G; Reitter, S; Sill, H; Olschewski, H Screening for pulmonary hypertension in patients with myelodysplastic syndromes
WIEN KLIN WOCHENSCHR. . 2011; 123(17-18):A22-A23.-Jahrestagung 2011 der Österreichischen Gesellschaft für Pneumologie; [Poster]
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** Linkesch, W; Neumeister, P; Zinke-Cerwenka, W; Strunk, D; Sill, H UCBT with low-dose ATG in adults
BONE MARROW TRANSPLANT. 2011; 46: S128-S129. [Poster]
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** Zinke-Cerwenka, W; Rohn, A; Posch, U; Beham-Schmid, C; Linkesch, W; Wölfler, A; Sill, H Graft-versus-primary malignancy in patients with therapy-related myeloid neoplasms (t-MNs) undergoing reduced-intensity allogeneic hematopoietic stem cell transplantation (HSCT).
Onkologie. 2011; 34(6):274-274.-Jahrestagung der DÖuSGHO; SEP 30-OCT 04, 2011; Basel. [Poster]
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Abstract (Konferenzband)

** Zebisch, A; Wölfler, A; Hiden K; Bodner, C; Quehenberger, F; Drasche, A; Pirkebner, D; Haller, M; Matallanas, D; Fried, I; Rath, O; Blyth, K; Taskesen, E; Kolch, W; Troppmair, J; Sill, H RAF kinase inhibitor protein ist ein neuer Tumor-Suppressor bei der akuten myeloischen Leukämie
Onkologie. 2011; 34(S6):209-209.-Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie; SEP 30-OCT 4, 2011; Basel, Switzerland. (ISBN: 978-3-8055-9922-1 ) [Oral Communication]
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2010

Kurzbericht/Letter

** Zach, J; Zollner-Schwetz, I; Zebisch, A; Rohn, A; Sill, H; Krause, R Gram stain/aolc screening for detection of catheter related bloodstream infection.
J Infect. 2010; 60(3): 254-255. Doi: 10.1016/j.jinf.2010.01.001
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Übersichtsarbeit

** Wieser, R; Scheideler, M; Hackl, H; Engelmann, M; Schneckenleithner, C; Hiden, K; Papak, C; Trajanoski, Z; Sill, H; Fonatsch, C microRNAs in acute myeloid leukemia: expression patterns, correlations with genetic and clinical parameters, and prognostic significance.
Genes Chromosomes Cancer. 2010; 49(3):193-203 Doi: 10.1002/gcc.20740
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Abstract (Zeitschrift)

** Bodner, C; Pichler, MM; Deutsch, AJ; Beham-Schmid, C; Linkesch, W; Sill, H; Wolfler, A IDH mutations in therapy-related and secondary AML evolving from myelodysplastic syndromes.
ONKOLOGIE. 2010; 33: 232-233.-Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie; OCT 1-5, 2010; Berlin, GERMANY. [Poster]
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** Haller, M; Zebisch, A; Hiden, K; Hoefler, G; Sill, H; Troppmair, J Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations
FEBS J. 2010; 277: 127-127. [Poster]
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** Kqiku X; Kovacs G; Reitter S; Sill H; Olschewski H Prevalence of pulmonary hypertension in myelodysplastic syndrome.
Wien Klin Wochenschr (2010) 122/21-22:A47-A642010; 122: A50-A51.-Jahrestagung 2010 der österreichischen Gesellschaft für Pneumonologie; OCT 7-9, 2010; Graz. [Poster]
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** Krieger, O; Machhemdl-Spandl, S; Hauser, H; Binder, M; Greinix, H; Eder, S; Kahls, P; Rabitsch, W; Nachbaur, D; Ludwig, H; Linkesch, W; Jaeger, G; Sill, H; Lindner, B Stem cell transplantation for MDS patients 1987-2008: data from the Austrian transplant registry (ASCTR)
BONE MARROW TRANSPLANT. 2010; 45: S180-S181. -36th Annual Meeting of the European Group for Blood and Marrow Transplantation; MAR 21-24, 2010; Vienna, AUSTRIA. [Poster]
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** Zebisch, A; Woelfler, A; Hiden, K; Bodner, C; Quehenberger, F; Drasche, A; Pirkebner, D; Haller, M; Rath, O; Blyth, K; Taskesen, E; Kolch, W; Troppmair, J; Sill, H Loss of RAF Kinase Inhibitor Protein Is a Frequent Event In Acute Myeloid Leukemia with a Monocytic Phenotype and Cooperates with Mutant RAS In Malignant Transformation
BLOOD. 2010; 116(21): 1702-1702. [Poster]
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** Zebisch, A; Woelfler, A; Hiden, K; Bodner, C; Quehenberger, F; Drasche, A; Pirkebner, D; Rath, O; Blyth, K; Delwel, R; Taskesen, E; Kolch, W; Troppmair, J; Sill, H LOSS OF RKIP IN ACUTE MYELOID LEUKEMIA WITH A MONOCYTIC PHENOTYPE
HAEMATOL-HEMATOL J. 2010; 95: 0026 -Annual Meting of the European Haematology Association; June 2010; Barcelona. [Poster]
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2009

Originalarbeit (Zeitschrift)

** Zebisch, A; Haller, M; Hiden, K; Goebel, T; Hoefler, G; Troppmair, J; Sill, H Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations.
Leukemia. 2009; 23(6): 1049-1053. Doi: 10.1038/leu.2009.68 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Olipitz, W; Scheer, N; Quehenberger, F; Hiden, K; Rankl, J; Schlembach, D; Sill, H Base Excision Repair Deficiency in Acute Myeloid Leukemia.
BLOOD. 2009; 114(22): 454-454. [Poster]
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2008

Originalarbeit (Zeitschrift)

** Novak, M; Hiden, M; Rehak, T; Rosenkranz, A; Zebisch, A; Sill, H; Klaschka, S; Muntean, W Enhanced thrombin generation in plasma of severe thrombocytopenic patients due to rFVIIa.
HAMOSTASEOLOGIE. 2008; 28 Suppl 1(12): S77-S80. Doi: 10.1055/s-0037-1621422
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** Stauder, R; Wimazal, F; Nösslinger, T; Krieger, O; Sperr, WR; Sill, H; Pfeilstöcker, M; Valent, P Individualized management and therapy of myelodysplastic syndromes.
Wien Klin Wochenschr. 2008; 120(17-18): 523-537. Doi: 10.1007/s00508-008-1058-6
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** Valent, P; Krieger, O; Stauder, R; Wimazal, F; Nösslinger, T; Sperr, WR; Sill, H; Bettelheim, P; Pfeilstöcker, M Iron overload in myelodysplastic syndromes (MDS) - diagnosis, management, and response criteria: a proposal of the Austrian MDS platform.
Eur J Clin Invest. 2008; 38(3):143-149 Doi: 10.1111/j.1365-2362.2007.01915.x [OPEN ACCESS]
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** Zebisch, A; Sill, H Severe hemolysis as presenting sign of acute erythroleukemia.
J Clin Oncol. 2008; 26(2): 330-331. Doi: 10.1200/JCO.2007.14.1481 (- Case Report) [OPEN ACCESS]
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Kurzbericht/Letter

** Zebisch, A; Sill, H Are mouthwashes a reliable source of constitutional DNA in patients with leukemia?
Leuk Res. 2008; 32(7): 1164-1165. Doi: 10.1016/j.leukres.2007.11.003
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Übersichtsarbeit

** Sill, H Susceptibility to therapy-related myelodysplastic syndromes and acute myeloid leukemia.
Clin Adv Hematol Oncol. 2008; 6(3):164-165
PubMed

 

Abstract (Zeitschrift)

** Novak, M; Rosenkranz, A; Muntean, W; Zebisch, A; Sill, H; Hiden, M Recombinant factor VIIa enhances thrombin generation in plasma of severe thrombocytopenic patients.
HAEMOPHILIA. HAEMOPHILIA2008; 14: 9-9.-World Hemophilia Congress ; JUN 2-5, 2008; Istanbul, TÜRKEI. [Oral Communication]
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** Reitter, S; Posch, U; Eibl, M; Sill, H; Linkesch, W; Zinke-Cerwenka, W NONMYELOABLATIVE ALLOGENEIC STEM CELL TRANSPLANTATION IN PATIENTS WITH RICHTER SYNDROME: A REPORT OF TWO CASES
HAEMATOL-HEMATOL J. 2008; 93: 1410--13th Congress of the European-Hematology-Association; JUN 12-15, 2008; Copenhagen, DENMARK. [Poster]
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** Reitter, S; Zinke-Cerwenka, W; Zebisch, A; Sormann, S; Sill, H; Linkesch, W Haematopoetic stem cell transplantation in CLL: promising results using allogeneic reduced intensity conditioning compared with an autologous setting
BONE MARROW TRANSPLANT. 2008; 41: S309-S310.-34th Meeting oif the EBMT; MARCH 30- APR 2, 2008; Florence, ITALY. [Poster]
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** Zinke-Cerwenka, W; Posch, U; Sill, H; Eibl, E; Linkesch, W FOLLOW-UP OF PATIENTS WITH MULTIPLE MYELOMA UNDERGOING AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANTATION (PBSCT) FOLLOWED BY REDUCED-INTENSITY ALLOGENEIC PBSCT
HAEMATOL-HEMATOL J. 2008; 93: 1435 [Poster]
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** Zinke-Cerwenka, W; Posch, U; Zebisch, A; Linkesch, W; Sill, H Results of umbilical cord blood transplantations in adults with high-risk haematologic malignancies
BONE MARROW TRANSPLANT. BONE MARROW TRANSPLANTATION.2008; 41: S158-S158.-34th Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation/24nd Meeting of the EBMT-Nurses-Group/7th Meeting of the EBMT-Data-Management-Group; MAR 30-APR 02, 2008; Florence, ITALY. [Poster]
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** Zinke-Cerwenka, W; Stojakovic, T; Sill, H; Eibl, E; Linkesch, W PROMISING THERAPY RESPONSE IN MULTIPLE MYELOMA PATIENTS TREATED WITH INDUCTION CHEMOTHERAPY CONSISTING OF BORTEZOMIB, DOXORUBICIN AND DEXAMETHASONE FOLLOWED BY AUTOLOGOUS STEM CELL TRANSPLANTATION
HAEMATOL-HEMATOL J. 2008; 93: 0222--13th Congress of the European-Hematology-Association; JUN 12-15, 2008; Copenhagen, DENMARK. [Poster]
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** Zinke-Cerwenka, W; Stojakovic, T; Zebisch, A; Sill, H; Linkesch, W Promising results in multiple myeloma patients treated with induction chemotherapy consisting of bortezomib, doxorubicin and dexamethasone followed by autologous stem cell transplantation
BONE MARROW TRANSPLANT. 2008; 41: S185-S185.-34th Meeting of the EBMT; March 30- APR 2, 2008; [Poster]
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2007

Kurzbericht/Letter

** Sill, H; Zinke-Cerwenka, W; Berghold, A Autologous stem cell transplantation for therapy-related acute myeloid leukemia and myelodysplastic syndrome.
Bone Marrow Transplant. 2007; 39(8):509; author reply 509-509; author reply 510 Doi: 10.1038/sj.bmt.1705603 [OPEN ACCESS]
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** Weingrill, E; Wölfler, A; Strunk, D; Linkesch, W; Sill, H; Liebmann, PM Roscovitine in B-chronic lymphocytic leukemia cells: high apoptosis-inducing efficacy and synergism with alemtuzumab independent of the patients' pretreatment status.
Haematologica. 2007; 92(9): 1286-1288. Doi: 10.3324/haematol.10680 [OPEN ACCESS]
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Übersichtsarbeit

** Zebisch, A; Czernilofsky, AP; Keri, G; Smigelskaite, J; Sill, H; Troppmair, J Signaling through RAS-RAF-MEK-ERK: from basics to bedside.
Curr Med Chem. 2007; 14(5): 601-623. Doi: 10.2174/092986707780059670
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2006

Originalarbeit (Zeitschrift)

** Zebisch, A; Staber, PB; Delavar, A; Bodner, C; Hiden, K; Fischereder, K; Janakiraman, M; Linkesch, W; Auner, HW; Emberger, W; Windpassinger, C; Schimek, MG; Hoefler, G; Troppmair, J; Sill, H Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
Cancer Res. 2006; 66(7):3401-3408 Doi: 10.1158/0008-5472.CAN-05-0115 [OPEN ACCESS]
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Kurzbericht/Letter

** Sill, H Congo red-negative light chain disease - Immunofixation and light chain quantification
INTERNIST. 2006; 47: 273-273. Doi: 10.1007/s00108-006-1593-z
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Abstract (Zeitschrift)

** Langner, S; Staber, P; Radspieler, G; Triebl-Roth, K; Urban, C; Zinke-Cerwenka, W; Sill, H; Linkesch, W; Neumeister, P Palifermin reduces oral mucositis and enhances the recovery of intestinal mucosa measured by citrulline serum levels in allogeneic and autologous stem cell transplant recipients
BONE MARROW TRANSPLANT. 37: S73-S74.-32nd Annual Meeting of the European-Group-for-Blood-and-Morrow-Transplantation/22nd Meeting of the EBMT-Nures-Group/5th Meeting of the EMBT-Data-Management-Group; MAR 19-22, 2006; Hamburg, GERMANY. [Poster]
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** Zinke-Cerwenka, W; Eibl, M; Neumeister, P; Sill, H; Linkesch, W Late effects after autologous peripheral blood stem cell transplantation followed by reduced-intensity allogeneic peripheral blood stem cell transplantation in patients with multiple myeloma
BONE MARROW TRANSPLANT. ; 37: S113-S113.-32nd Annual Meeting of the European-Group-for-Blood-and-Morrow-Transplantation/22nd Meeting of the EBMT-Nures-Group/5th Meeting of the EMBT-Data-Management-Group; MAR 19-22, 2006; Hamburg, GERMANY. [Poster]
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2005

Originalarbeit (Zeitschrift)

** Auner, HW; Zebisch, A; Ofner, P; Sill, H; Linkesch, W; Krause, R Evaluation of potential risk factors for early infectious complications after autologous peripheral blood stem cell transplantation in patients with lymphoproliferative diseases.
ANN HEMATOL. 2005; 84: 532-537. Doi: 10.1007/s00277-005-1025-5
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** Wölfler, A; Erkeland, SJ; Bodner, C; Valkhof, M; Renner, W; Leitner, C; Olipitz, W; Pfeilstöcker, M; Tinchon, C; Emberger, W; Linkesch, W; Touw, IP; Sill, H A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome.
Blood. 2005; 105(9):3731-3736 Doi: 10.1182/blood-2004-06-2094 [OPEN ACCESS]
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** Zebisch, A; Linkesch, W; Sill, H Bedside RNA stabilizing kit systems for gene expression analysis of acute leukemias: influence of non-neoplastic white blood cells.
Leukemia. 2005; 19(4):685-685 Doi: 10.1038/sj.leu.2403713 [OPEN ACCESS]
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Kurzbericht/Letter

** Sill, H; Neubauer, M Diagnosis from the blood smear.
N ENGL J MED 2005 353: 1862-1862. Doi: 10.1056/NEJM200510273531722 [OPEN ACCESS]
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** Sill, H; Olipitz, W; Schimek, MG Therapy-related myelodysplastic syndrome and acute myeloid leukemia after autologous bone marrow transplantation: dosis facit venenum?
J CLIN ONCOL. 2005; 23: 8120-8121. Doi: 10.1200/JCO.2005.03.0643 [OPEN ACCESS]
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** Zebisch, A; Linkesch, W; Sill, H Bedside RNA stabilizing kit systems for gene expression analysis of acute leukemias: influence of non-neoplastic white blood cells.
LEUKEMIA. 2005; 19: 136-137. Doi: 10.1038/sj.leu.2403581 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Zinke-Cerwenka, W; Neumeister, P; Eibl, M; Sill, H; Emberger, W; Wagner, T; Wolfler, A; Linkesch, W Planned sequential autologous/non-myeloablative allogeneic peripheral stem cell transplantation in patients with newly diagnosed high-risk multiple myeloma
BONE MARROW TRANSPLANT 2005 35: S387-S388.
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2004

Originalarbeit (Zeitschrift)

** Auner, HW; Zebisch, A; Schimek, MG; Bodner, C; Hiden, K; Linkesch, W; Haas, OA; Beham-Schmid, C; Sill, H High expression of the sister-chromatid separation regulator and proto-oncogene hSecurin occurs in a subset of myeloid leukaemias but is not implicated in the pathogenesis of aneuploidy.
Leukemia. 2004; 18(2):303-308 Doi: 10.1038/sj.leu.2403235 [OPEN ACCESS]
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** Eibl, M; Auner, HW; Zinke-Cerwenka, W; Sill, H; Dornbusch, HJ; Linkesch, W High-risk AML complicated by pulmonary aspergillosis: successful treatment with nonmyeloablative stem cell transplantation and long-term administration of voriconazole.
ANN HEMATOL. 2004; 83(2): 133-136. Doi: 10.1007/s00277-003-0782-2 (- Case Report)
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** Mulabecirovic, A; Gaulhofer, P; Auner, HW; Popper, H; Krause, R; Hesse, C; Sill, H Pulmonary infiltrates in patients with haematologic malignancies: transbronchial lung biopsy increases the diagnostic yield with respect to neoplastic infiltrates and toxic pneumonitis.
ANN HEMATOL. 2004; 83(7): 420-422. Doi: 10.1007/s00277-004-0876-5
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** Olipitz, W; Strunk, D; Beham-Schmid, C; Sill, H Neutrophilic leukemoid reaction as the presenting feature of de novo and therapy-related acute leukemias.
ACTA HAEMATOL. 2004; 111(4): 233-234. Doi: 10.1159/000077574 (- Case Report)
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** Schmidt, HH; Strehl, S; Thaler, D; Strunk, D; Sill, H; Linkesch, W; Jäger, U; Sperr, W; Greinix, HT; König, M; Emberger, W; Haas, OA RT-PCR and FISH analysis of acute myeloid leukemia with t(8;16)(p11;p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical implications.
Leukemia. 2004; 18(6):1115-1121 Doi: 10.1038/sj.leu.2403353 (- Case Report) [OPEN ACCESS]
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** Staber, PB; Linkesch, W; Zauner, D; Beham-Schmid, C; Guelly, C; Schauer, S; Sill, H; Hoefler, G Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia.
Oncogene. 2004; 23(4):894-904 Doi: 10.1038/sj.onc.1207192 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Eibl, M; Auner, H; Zinke-Cerwenka, W; Sill, H; Linkesch, W Autologous stem cell transplantation with alemtuzumab as part of the conditioning for B-cell prolymphocytic leukaemia
BONE MARROW TRANSPLANT 2004 33: S290-S290.
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** Eibl, M; Zinke-Cerwenka, W; Neumeister, P; Wolfler, A; Sill, H; Linkesch, W Autologous stem cell transplantation for multiple myeloma in elderly patients
BONE MARROW TRANSPLANT 2004 33: S357-S357.
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** Zebisch, A; Staber, PB; Fischereder, K; Bodner, C; Hiden, K; Linkesch, W; Auner, HW; Emberger, W; Windpassinger, C; Schimek, MG; Hoefler, G; Troppmair, J; Sill, H Two novel activating germline mutations of the C-RAF proto-oncogene predisposing to solid tbmors and therapy-related acute myeloid leukemia.
BLOOD 2004 104: 920A-920A. Doi: 10.1182/blood.V104.11.3370.3370
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** Zinke-Cerwenka, W; Eibl, M; Sill, H; Hofler, G; Staber, P; Linkesch, W Continuous molecular response after discontinuation of imatinib mesylate following relapse after non-myeloablative allogeneic stem cell transplantation for CML
BONE MARROW TRANSPLANT 2004 33: S348-S348.
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2003

Originalarbeit (Zeitschrift)

** Auner, HW; Tinchon, C; Linkesch, W; Tiran, A; Quehenberger, F; Link, H; Sill, H Prolonged monitoring of troponin T for the detection of anthracycline cardiotoxicity in adults with hematological malignancies.
Ann Hematol. 2003; 82(4):218-222 Doi: 10.1007/s00277-003-0615-3
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** Bauernhofer, T; Eibl, M; Ploner, F; Kuss, I; Pfeifer, J; Sill, H; Samonigg, H Acute pseudo-obstruction of the small intestine following high-dose chemotherapy and stem cell support.
Onkologie. 2003; 26(4):344-346 Doi: 10.1159/000072093 (- Case Report)
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** Staber, PB; Brezinschek, R; Linkesch, W; Sill, H; Neumeister, P Durable molecular response to imatinib mesylate following nonmyeloablative allogeneic stem-cell transplantation for persisting myeloid blast crisis in chronic myeloid leukemia.
Haematologica. 2003; 88(8):ECR29-ECR29 (- Case Report) [OPEN ACCESS]
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** Zebisch, A; Cerroni, L; Beham-Schmid, C; Sill, H Therapy-related leukemia cutis: case study of an aggressive disorder.
ANN HEMATOL 2003 82: 705-707. Doi: 10.1007/s00277-003-0717-y (- Case Report)
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Kurzbericht/Letter

** Wölfler, A; Bauer, F; Zollner, G; Weber, K; Sill, H; Linkesch, W Fatal sepsis after thalidomide/dexamethasone treatment in two patients with multiple myeloma.
Haematologica. 2003; 88(4): ELT12-ELT12. (- Case Report) [OPEN ACCESS]
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Abstract (Zeitschrift)

** Wölfler, A; Erkeland, S; Leitner, C; Olipitz, W; Bodner, C; Wagner, T; Linkesch, W; Touw, IP; Sill, H A functional polymorphism of the granulocyte colony-stimulating factor receptor is associated with increased risk of myelodysplastic syndrome.
BLOOD 2003 102: 915A-916A.
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2002

Originalarbeit (Zeitschrift)

** Auner, HW; Sill, H; Mulabecirovic, A; Linkesch, W; Krause, R Infectious complications after autologous hematopoietic stem cell transplantation: comparison of patients with acute myeloid leukemia, malignant lymphoma, and multiple myeloma.
ANN HEMATOL 2002 81: 374-377. Doi: 10.1007/s00277-002-0484-1
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** Auner, HW; Tinchon, C; Brezinschek, RI; Eibl, M; Sormann, S; Maizen, C; Linkesch, W; Schmon-Kampel, R; Quehenberger, F; Tiran, A; Sill, H Monitoring of cardiac function by serum cardiac troponin T levels, ventricular repolarisation indices, and echocardiography after conditioning with fractionated total body irradiation and high-dose cyclophosphamide.
Eur J Haematol. 2002; 69(1):1-6 Doi: 10.1034%2Fj.1600-0609.2002.01661.x
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** Beham-Schmid, C; Apfelbeck, U; Sill, H; Tsybrovsky, O; Höfler, G; Haas, OA; Linkesch, W Treatment of chronic myelogenous leukemia with the tyrosine kinase inhibitor STI571 results in marked regression of bone marrow fibrosis.
Blood. 2002; 99(1):381-383 Doi: 10.1182/blood.V99.1.381 [OPEN ACCESS]
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** Jäeger, G; Neumeister, P; Brezinschek, R; Höfler, G; Quehenberger, F; Linkesch, W; Sill, H Rituximab (anti-CD20 monoclonal antibody) as consolidation of first-line CHOP chemotherapy in patients with follicular lymphoma: a phase II study.
EUR J HAEMATOL 2002 69: 21-26. Doi: 10.1034%2Fj.1600-0609.2002.01692.x
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** Olipitz, W; Hopfinger, G; Aguiar, RC; Gunsilius, E; Girschikofsky, M; Bodner, C; Hiden, K; Linkesch, W; Hoefler, G; Sill, H Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia.
Genes Chromosomes Cancer. 2002; 34(2):243-248 Doi: 10.1002/gcc.10059
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** Petzer, AL; Hochenburger, E; Haun, M; Duba, HCh; Grünewald, K; Hoflehner, E; Sill, H; Linkesch, W; Gastl, G; Gunsilius, E High-dose hydroxyurea plus G-CSF mobilize BCR-ABL-negative progenitor cells (CFC, LTC-IC) into the blood of newly diagnosed CML patients at any time of hematopoietic regeneration.
J HEMATOTHER STEM CELL RES 2002 11: 293-300. Doi: 10.1089/152581602753658475
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** Tinchon, C; Auner, HW; Beham-Schmid, C; Aberle, SW; Sill, H; Linkesch, W Symptomatic Epstein-Barr virus reactivation in a patient with acute myeloid leukaemia and treatment with the monoclonal anti-CD20 antibody rituximab.
EUR J HAEMATOL 2002 69: 50-53. Doi: 10.1034%2Fj.1600-0609.2002.02740.x (- Case Report)
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Kurzbericht/Letter

** Auner, HW; Wölfler, A; Beham-Schmid, C; Strunk, D; Linkesch, W; Sill, H Restoration of erythropoiesis by rituximab in an adult patient with primary acquired pure red cell aplasia refractory to conventional treatment.
BRIT J HAEMATOL 2002 116: 727-728. Doi: 10.1046%2Fj.1365-2141.2002.3317_3.x (- Case Report) [OPEN ACCESS]
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2001

Originalarbeit (Zeitschrift)

** Neumeister, P; Eibl, M; Zinke-Cerwenka, W; Scarpatetti, M; Sill, H; Linkesch, W Hepatic veno-occlusive disease in two patients with relapsed acute myeloid leukemia treated with anti-CD33 calicheamicin (CMA-676) immunoconjugate.
Ann Hematol. 2001; 80(2):119-120 Doi: 10.1007%2Fs002770000239 (- Case Report)
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** Tanner, SM; Austin, JL; Leone, G; Rush, LJ; Plass, C; Heinonen, K; Mrózek, K; Sill, H; Knuutila, S; Kolitz, JE; Archer, KJ; Caligiuri, MA; Bloomfield, CD; de La Chapelle, A BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.
Proc Natl Acad Sci U S A. 2001; 98(24):13901-13906 Doi: 10.1073/pnas.241525498 [OPEN ACCESS]
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Kurzbericht/Letter

** Auner, HW; Tinchon, C; Quehenberger, F; Linkesch, W; Sill, H Troponins in prediction of cardiotoxic effects.
Lancet. 2001; 357(9258):808-808 Doi: 10.1016/S0140-6736(05)71241-1
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** Olipitz, W; Tilz, GP; Beham-Schmid, C; Eibinger, C; Kerzina, P; Sill, H Microsatellite analysis in acute myeloid leukaemia evolving from myelodysplastic syndrome.
Br J Haematol. 2001; 112(1):248-249 Doi: 10.1046%2Fj.1365-2141.2001.02497.x [OPEN ACCESS]
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Abstract (Zeitschrift)

** Auner, HW; Tinchon, C; Brezinschek, RI; Eibl, M; Sormann, S; Maizen, C; Linkesch, W; Schmon-Kampel, R; Sill, H Serum cardiac troponin T (cTnT) levels, ventricular repolarization indices and echocardiographic parameters after fractionated total body irradiation and high-dose cyclophosphamide (fTBI/Cy).
BLOOD 2001 98: 5138-5138.
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Kommentar

** Auner, HW; Tinchon, C; Linkesch, W; Halwachs-Baumann, G; Sill, H Correspondence re: O. J. Arola et al., acute doxorubicin cardiotoxicity involves cardiomyocyte apoptosis. Cancer Res., 60: 1789-1792, 2000.
Cancer Res. 2001; 61(5):2335-2336 [OPEN ACCESS]
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2000

Originalarbeit (Zeitschrift)

** Apfelbeck, U; Hoefler, G; Neumeister, P; Fonatsch, C; Linkesch, W; Sill, H Extramedullary T cell lymphoblastic transformation of chronic myeloid leukaemia successfully treated with matched unrelated donor bone marrow transplantation.
BONE MARROW TRANSPLANT 2000 26: 1111-1112. Doi: 10.1038/sj.bmt.1702665 (- Case Report) [OPEN ACCESS]
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** Neumeister, P; Hoefler, G; Beham-Schmid, C; Sill, H; Linkesch, W Complete remission of generalized relapsed extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type of the gastrointestinal tract after high-dose chemotherapy and autologous peripheral stem cell transplantation.
ANN HEMATOL 2000 79: 703-705. Doi: 10.1007%2Fs002770000203 (- Case Report)
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** Neumeister, P; Strunk, D; Apfelbeck, U; Sill, H; Linkesch, W Adoptive transfer of vitiligo after allogeneic bone marrow transplantation for non-Hodgkin's lymphoma.
Lancet. 2000; 355(9212):1334-1335 Doi: 10.1016/S0140-6736(00)02120-6 (- Case Report)
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** Olipitz, W; Beham-Schmid, C; Aigner, R; Raith, J; Linkesch, W; Sill, H Acute myelofibrosis: multifocal bone marrow infiltration detected by scintigraphy and magnetic resonance imaging.
ANN HEMATOL 2000 79: 275-278. Doi: 10.1007%2Fs002770050593 (- Case Report)
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Kurzbericht/Letter

** Auner, HW; Beham-Schmid, C; Lindner, G; Fickert, P; Linkesch, W; Sill, H Successful nonsurgical treatment of primary mucosa-associated lymphoid tissue lymphoma of colon presenting with multiple polypoid lesions.
Am J Gastroenterol. 2000; 95(9):2387-2389 Doi: 10.1111/j.1572-0241.2000.02343.x (- Case Report)
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Korrektur

** Olipitz, W; Sill, H Genomic structure of the human DNA mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC).
HUM MOL GENET 2000 9: 321-321. [OPEN ACCESS]
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Abstract (Zeitschrift)

** Olipitz, W; Hopfinger, G; Hoefler, G; Girschikofsky, M; Bodner, C; Hiden, K; Aguiar, R; Linkesch, W; Sill, H Microsatellite instability but lack of alternations of genes targeted by defective DNA-mismatch repair in therapy-related MDS and leukemia.
BLOOD 2000 96: 104A-104A.
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1999

Originalarbeit (Zeitschrift)

** Auner, HW; Klintschar, M; Crevenna, R; Beham-Schmid, C; Hoefler, G; Mitterbauer, G; Linkesch, W; Sill, H Two case studies of chronic idiopathic neutropenia preceding acute myeloid leukaemia.
Br J Haematol. 1999; 105(2):431-433 Doi: 10.1046%2Fj.1365-2141.1999.01322.x (- Case Report) [OPEN ACCESS]
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** Auner, HW; Olipitz, W; Hoefler, G; Bodner, C; Konrad, D; Crevenna, R; Linkesch, W; Sill, H Mutational analysis of the DNA mismatch repair gene hMLH1 in myeloid leukaemias.
Br J Haematol. 1999; 106(3):706-708 Doi: 10.1046%2Fj.1365-2141.1999.01595.x [OPEN ACCESS]
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** Dahia, PL; Aguiar, RC; Alberta, J; Kum, JB; Caron, S; Sill, H; Marsh, DJ; Ritz, J; Freedman, A; Stiles, C; Eng, C PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies.
Hum Mol Genet. 1999; 8(2):185-193 Doi: 10.1093%2Fhmg%2F8.2.185 [OPEN ACCESS]
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** Feigl, B; Sill, H; Haas, A Serous detection of the neuroretina in Waldenström disease. A case report
Klin Monatsbl Augenheilkd. 1999; 215(1):64-67 Doi: 10.1055/s-2008-1034672 (- Case Report) [OPEN ACCESS]
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** Kenner, L; Beham-Schmid, C; Kerbl, R; Schmidt, HH; Sill, H; Hoefler, G ABL amplification in a patient with lymphoid blast crisis of chronic myelogenous leukaemia.
Virchows Arch. 1999; 434(3):255-257 Doi: 10.1007%2Fs004280050337 (- Case Report)
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** Lipp, RW; Schnedl, WJ; Aglas, F; Ranner, G; Beham-Schmid, C; Leb, G; Sill, H Visualization of non-Hodgkin's lymphoma by high dosed somatostatin receptor specific scintigraphy and extended single photon emission tomography.
Acta Med Austriaca. 1999; 26(3):105-108
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1998

Originalarbeit (Zeitschrift)

** Carapeti, M; Aguiar, RC; Sill, H; Goldman, JM; Cross, NC Aberrant transcripts of the FHIT gene are expressed in normal and leukaemic haemopoietic cells.
Br J Cancer. 1998; 78(5):601-605 Doi: 10.1038/bjc.1998.547 [OPEN ACCESS]
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** Fickert, P; Trauner, M; Sill, H; Hinterleitner, TA; Stauber, RE Successful steroid treatment of idiopathic thrombocytopenic purpura after orthotopic liver transplantation for primary biliary cirrhosis.
Am J Gastroenterol. 1998; 93(10):1985-1986 Doi: 10.1111/j.1572-0241.1998.00561.x (- Case Report)
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** Hilbe, W; Sill, H; Eisterer, W; Lin, F; Bechter, O; Grünewald, K; Thaler, J Long-lasting haematological remission despite persistence of the Philadelphia-positive clone in an untreated chronic myeloid leukaemia patient.
Acta Haematol. 1998; 100(2):101-103 Doi: 10.1159/000040877 (- Case Report)
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** Schmidt, HH; Pirc-Danoewinata, H; Panzer-Grümayer, ER; Sill, H; Sedlmayr, P; Neumeister, P; Linkesch, W; Haas, OA Translocation (3;5)(p26;q13) in a patient with chronic T-cell lymphoproliferative disorder.
Cancer Genet Cytogenet. 1998; 104(2):82-85 Doi: 10.1016/S0165-4608(97)00453-6 (- Case Report)
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Kurzbericht/Letter

** Cerroni, L; Metzler, G; Schmidt, H; Soyer, HP; Sill, H; Kerl H Cutaneous infiltrates of myelogenous leukemia in association with pre-existing skin diseases.
J CUTAN PATHOL . 1998; 25: 186-186. Doi: 10.1111/j.1600-0560.1998.tb01716.x (- Case Report)
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** Schmidt, HH; Neumeister, P; Kainer, F; Karpf, EF; Linkesch, W; Sill, H Treatment of essential thrombocythemia during pregnancy: antiabortive effect of interferon-alpha?
Ann Hematol. 1998; 77(6):291-292 Doi: 10.1007%2Fs002770050461
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Abstract (Zeitschrift)

** Schmidt, HH; Sill, H; Jager, G; Neumeister, P; Strunk, D; Linkesch, W Capillary leak syndrome with late onset after autografting for multiple myeloma.
BONE MARROW TRANSPLANT 1998 21: S91-S91.
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1997

Originalarbeit (Zeitschrift)

** Aguiar, RC; Sill, H; Goldman, JM; Cross, NC The commonly deleted region at 9p21-22 in lymphoblastic leukemias spans at least 400 kb and includes p16 but not p15 or the IFN gene cluster.
Leukemia. 1997; 11(2):233-238 Doi: 10.1038/sj.leu.2400553 [OPEN ACCESS]
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** Aigner, RM; Fueger, GF; Zinke, W; Sill, H 99Tcm-tetrofosmin scintigraphy in Hodgkin's disease.
Nucl Med Commun. 1997; 18(3):252-257 Doi: 10.1097/00006231-199703000-00009
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** Carapeti, M; Soede-Bobok, A; Hochhaus, A; Sill, H; Touw, IP; Goldman, JM; Cross, NC Rarity of dominant-negative mutations of the G-CSF receptor in patients with blast crisis of chronic myeloid leukemia or de novo acute leukemia.
Leukemia. 1997; 11(7):1005-1008 Doi: 10.1038%2Fsj.leu.2400697 [OPEN ACCESS]
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** Metzler, G; Cerroni, L; Schmidt, H; Soyer, HP; Sill, H; Kerl, H Leukemic cells within skin lesions of psoriasis in a patient with acute myelogenous leukemia.
J Cutan Pathol. 1997; 24(7):445-448 Doi: 10.1111/j.1600-0560.1997.tb00821.x (- Case Report)
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** Neumeister, P; Hoefler, G; Beham-Schmid, C; Schmidt, H; Apfelbeck, U; Schaider, H; Linkesch, W; Sill, H Deletion analysis of the p16 tumor suppressor gene in gastrointestinal mucosa-associated lymphoid tissue lymphomas.
Gastroenterology. 1997; 112(6):1871-1875 Doi: 10.1053%2Fgast.1997.v112.pm9178679
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** Thaler, J; Hilbe, W; Apfelbeck, U; Linkesch, W; Sill, H; Seewann, H; Pont, J; Bernhart, M; Stöger, M; Niessner, H; Abbrederis, K; Geissler, D; Hausmaninger, H; Lin, W; Ludwig, H; Lang, A; Duba, C; Fluckinger, T; Greil, R; Grünewald, K; Konwalinka, G; Niederwieser, D; Fridrik, M Interferon-alpha-2C and LD ara-C for the treatment of patients with CML: results of the Austrian multi-center phase II study.
Leuk Res. 1997; 21(1):75-80 Doi: 10.1016%2FS0145-2126%2896%2900084-7
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1996

Originalarbeit (Zeitschrift)

** Aguiar, RC; Dahia, PL; Sill, H; Toledo, SP; Goldman, JM; Cross, NC Deletion analysis of the p16 tumour suppressor gene in phaeochromocytomas.
Clin Endocrinol (Oxf). 1996; 45(1):93-96 Doi: 10.1046/j.1365-2265.1996.00762.x
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** Fridrik, MA; Hausmaninger, H; Linkesch, W; Stöger, M; Sill, H; Neubauer, M; Seewann, HL; Klocker, J; Haidinger, R; Schiller, L; Pont, J; Raudaschl, G; Falk, M; Radaszkiewicz, T CEOP-IMVP-Dexa in the treatment of aggressive lymphomas: an Austrian multicenter trial.
J CLIN ONCOL. 1996; 14(1): 227-232. Doi: 10.1200/JCO.1996.14.1.227 [OPEN ACCESS]
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** Lipp, RW; Sill, H; Aigner, R; Ranner, G; Hoefler, G; Passath, A; Leb, G Gallium-67-citrate scintigraphy of high-grade T-cell non-Hodgkin's lymphoma.
J NUCL MED 1996 37: 1524-1525. (- Case Report) [OPEN ACCESS]
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** Sill, H; Aguiar, RC; Schmidt, H; Hochhaus, A; Goldman, JM; Cross, NC Mutational analysis of the p15 and p16 genes in acute leukaemias.
BRIT J HAEMATOL. 1996; 92(3): 681-683. Doi: 10.1046%2Fj.1365-2141.1996.340858.x
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** Sill, H; Goldman, JM; Cross, NC Rarity of microsatellite alterations in acute myeloid leukaemia.
Br J Cancer. 1996; 74(2):255-257 Doi: 10.1038/bjc.1996.347 [OPEN ACCESS]
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** Sill, H; Rule, SA; Joske, DJ; Chase, A; Lin, F; Goldman, JM; Cross, NC Reconstitution with Philadelphia chromosome-negative recipient haematopoiesis early after allogeneic BMT for CML.
Bone Marrow Transplant. 1996; 17(3):453-455 (- Case Report)
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** Thaler, J; Gastl, G; Fluckinger, T; Niederwieser, D; Huber, H; Seewann, H; Sill, H; Lang, A; Falk, M; Duba, C; Utermann, G; Kühr, T; Aulitzky, W; Huber, C Interferon alpha-2c therapy of patients with chronic myelogenous leukemia: long-term results of a multicenter phase-II study. Austrian Biological Response Modifier (BRM) Study Group.
Ann Hematol. 1996; 72(6):349-355 Doi: 10.1007/s002770050185
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Kurzbericht/Letter

** Aguiar, RC; Sill, H; Hochhaus, A; Goldman, JM; Cross, NC Molecular investigation of secondary chronic myeloid leukemia.
Blood. 1996; 88(7):2808-2809 Doi: 10.1182/blood.V88.7.2808.bloodjournal8872808 [OPEN ACCESS]
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** Neumeister, P; Linkesch, W; Höfler, G; Sill, H 2-Chlorodeoxyadenosine as first-line treatment in bronchus-associated lymphoid tissue lymphoma.
Blood. 1996; 87(8):3526-3526 Doi: 10.1182/blood.V87.8.3526a.bloodjournal8783526a (- Case Report) [OPEN ACCESS]
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** Schmidt, HH; Höfler, G; Beham-Schmid, C; Sill, H; Linkesch, W Bone marrow granulomas in hairy cell leukaemia.
Histopathology. 1996; 29(3):291-292 Doi: 10.1111/j.1365-2559.1996.tb01409.x
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** Trinker, M; Hófler, G; Sill, H False-positive diagnosis of tuberculosis with PCR.
Lancet. 1996; 348(9038):1388-1388 Doi: 10.1016/S0140-6736(05)65458-X (- Case Report)
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Abstract (Zeitschrift)

** Aguiar, RCT; Sill, H; Goldman, JM; Cross, NCP Detailed deletion map of chromosome band 9p21-22 in primary and secondary acute lymphoblastic leukaemias
BRIT J HAEMATOL. 1996; 93: 136-136.
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** Hochhaus, A; Lin, F; Reiter, A; Skladny, H; Shepherd, PCA; Sill, H; Allan, NC; Hehlmann, R; Goldman, JM; Cross, NCP Levels of minimal residual disease in chronic myelogenous leukemia (CML) patients in complete cytogenetic remission after interferon-alpha-therapy correlate with risk of relapse.
EXP HEMATOL 1996 24: 579-579.
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** Neumeister, P; Hofler, G; BehamSchmid, C; Schmidt, H; Apfelbeck, U; Linkesch, W; Sill, H Homozygous deletions of the p16 gene in high-grade gastric malt lymphomas.
BLOOD 1996 88: 3311-3311.
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1995

Originalarbeit (Zeitschrift)

** Greinix, HT; Beham-Schmid, C; Silly, H; Hoefler, G; Kasparek, A; Seewann, HL Heavy-chain immunoglobulin gene rearrangement and cytoplasmic immunoglobulin expression in acute monocytic leukemia following primary germ cell tumor.
Ann Hematol. 1995; 70(2):109-112 Doi: 10.1007/BF01834391 (- Case Report)
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** Lipp, RW; Silly, H; Ranner, G; Dobnig, H; Passath, A; Leb, G; Krejs, GJ Radiolabeled octreotide for the demonstration of somatostatin receptors in malignant lymphoma and lymphadenopathy.
J Nucl Med. 1995; 36(1):13-18 [OPEN ACCESS]
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** Sill, H; Goldman, JM; Cross, NC Homozygous deletions of the p16 tumor-suppressor gene are associated with lymphoid transformation of chronic myeloid leukemia.
Blood. 1995; 85(8):2013-2016 Doi: 10.1182/blood.V85.8.2013.bloodjournal8582013 [OPEN ACCESS]
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** Sill, H; Höfler, G; Kaufmann, P; Horina, J; Spuller, E; Kleinert, R; Beham-Schmid, C Angiotropic large cell lymphoma presenting as thrombotic microangiopathy (thrombotic thrombocytopenic purpura).
Cancer. 1995; 75(5):1167-1170 Doi: 10.1002/1097-0142(19950301)75:5<1167::AID-CNCR2820750517>3.0.CO;2-1 (- Case Report) [OPEN ACCESS]
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Übersichtsarbeit

** Schmidt, HH; Sill, H; Eibl, M; Beham-Schmid, C; Höfler, G; Haas, OA; Krejs, GJ; Linkesch, W Hodgkin's disease developing after spontaneous remission of chronic lymphocytic leukemia.
Ann Hematol. 1995; 71(5):247-252 Doi: 10.1007/s002770050113 (- Case Report)
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1994

Originalarbeit (Zeitschrift)

** Hilbe, W; Eisterer, W; Schmid, C; Starz, I; Silly, H; Duba, C; Ludescher, C; Thaler, J Bone marrow lymphocyte subsets in myelodysplastic syndromes.
J CLIN PATHOL. 1994; 47(6): 505-507. Doi: 10.1136/jcp.47.6.505 [OPEN ACCESS]
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** Sill, H; Chase, A; Mills, KI; Apfelbeck, U; Sormann, S; Goldman, JM; Cross, NC No evidence for microsatellite instability or consistent loss of heterozygosity at selected loci in chronic myeloid leukaemia blast crisis.
LEUKEMIA. 1994; 8(11): 1923-1928.
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** Silly, H; Schmid, C; Greinix, H; Dobnig, H; Seewann, H; Neubauer, M Suppression of chronic lymphocytic leukaemia by megakaryocytic myelosis.
Haematologia (Budap). 1994; 26(1):11-15 (- Case Report)
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Kurzbericht/Note

** Silly, H; Wilderstruschnig, M; Brezinschek, R; Brezinschek, HP; Schmid, M; Kuss, I; Mucher, K; Stöger, H; Samonigg, H Varying Amounts of Tumor-Cells in the Bone-Marrow of Patients with Nonmetastatic Colorectal-Cancer
ONKOLOGIE. 1994; 17: 184-186. Doi: 10.1159/000218406
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Kommentar

** Cross, NC; Silly, H; Goldman, JM Microsatellite instability in myeloid leukemias.
Blood. 1994; 84(9): 3236-3236. Doi: 10.1182/blood.V84.9.3236.bloodjournal8493236 [OPEN ACCESS]
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1993

Originalarbeit (Zeitschrift)

** Horina, JH; Petritsch, W; Schmid, CR; Reicht, G; Wenzl, H; Silly, H; Krejs, GJ Treatment of anemia in inflammatory bowel disease with recombinant human erythropoietin: results in three patients.
Gastroenterology. 1993; 104(6):1828-1831 Doi: 10.1016/0016-5085(93)90666-Z
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** THALER, J; GASTL, G; FLUCKINGER, T; NIEDERWIESER, D; HUBER, H; SEEWANN, H; SILLY, H; LANG, A; ABBREDERIS, C; GADNER, H; FEREBERGER, W; SCHILLER, L; KOCK, L; FRIDRIK, M; DUBA, C; FALK, M; BERGER, M; KUHR, T; HUBER, C TREATMENT OF CHRONIC MYELOGENOUS LEUKEMIA WITH INTERFERON-ALFA-2C - RESPONSE RATE AND TOXICITY IN A PHASE-II MULTICENTER STUDY
SEMIN HEMATOL. 1993; 30(3): 17-19. Doi: 10.1016/0145-2126(93)90079-Z
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Kurzbericht/Note

** Thaler, J; Fluckinger, T; Huber, H; Lang, A; Abbrederis, C; Seewann, H; Silly, H; Baldinger, C; Duba, C; Huber, C Treatment of 11 patients with chronic myelogenous leukemia with interferon-alpha-2C and low-dose cytosine arabinoside.
LEUK RES. 1993; 17(8): 711-715. Doi: 10.1016/0145-2126(93)90079-Z
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1992

Originalarbeit (Zeitschrift)

** Dobnig, H; Silly, H; Ohlinger, W; Neubauer, M; Leb, G; Krejs, GJ Successful treatment of primary adrenal insufficiency due to malignant non-Hodgkin's lymphoma.
Clin Investig. 1992; 70(10):938-941 Doi: 10.1007/BF00180443 (- Case Report)
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Kurzbericht/Letter

** Reisinger, EC; Silly, HL; Smolle, KH; Krejs, GJ Exchange transfusion for severe falciparum malaria?
Infection. 1992; 20(3):174-175 Doi: 10.1007/BF01704617 (- Case Report)
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** Silly, H; Samonigg, H; Stöger, H; Brezinschek, HP; Wilders-Truschnig, M Micrometastatic tumour cells in bone marrow in colorectal cancer.
Lancet. 1992; 340(8830):1288-1288 Doi: 10.1016/0140-6736(92)92987-Q
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1991

Kurzbericht/Letter

** Horina, JH; Horn, S; Silly, H; Winkler, HM; Roob, JM; Kaufmann, P; Pogglitsch, H; Krejs, GJ Need for erythropoietin treatment in predialysis patients.
Lancet. 1991; 337(8740):562-562 Doi: 10.1016/0140-6736(91)91357-Z
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