Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Rodriguez Blanco Giovanny |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Tatzl, E; Petracco, G; Faimann, I; Balasso, M; Mooslechner, AA; Bärnthaler, T; Rodriguez-Blanco, G; Reichmann, F Deficiency of the Synaptic Adhesion Protein Leucine-Rich Repeat Transmembrane Protein 4 Like 1 Affects Anxiety and Aggression in Zebrafish.
Acta Physiol (Oxf). 2025; 241(5):e70042 Doi: 10.1111/apha.70042 [OPEN ACCESS]
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Kurzbericht/Letter

** Enko, D; Meinitzer, A; Dawczynski, C; Zelzer, S; Pilz, S; Niedrist, T; Blanco, GR; Herrmann, M The Exercise-Induced Appetite Suppressor N-Lactoyl-Phenylalanine is Linked with Glucose Metabolism.
Clin Lab. 2025; 71(3): Doi: 10.7754/Clin.Lab.2024.241016
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2024

Originalarbeit (Zeitschrift)

** Alonso, N; Almer, G; Semeraro, MD; Rodriguez-Blanco, G; Fauler, G; Anders, I; Ritter, G; Vom, Scheidt, A; Hammer, N; Gruber, HJ; Herrmann, M Impact of High-Fat Diet and Exercise on Bone and Bile Acid Metabolism in Rats.
NUTRIENTS. 2024; 16(11): Doi: 10.3390/nu16111744 [OPEN ACCESS]
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** Fitzinger, J; Rodriguez-Blanco, G; Herrmann, M; Borenich, A; Stauber, R; Aigner, E; Mangge, H Gender-Specific Bile Acid Profiles in Non-Alcoholic Fatty Liver Disease.
Nutrients. 2024; 16(2): Doi: 10.3390/nu16020250 [OPEN ACCESS]
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Übersichtsarbeit

** Herrmann, M; Rodriguez-Blanco, G; Balasso, M; Sobolewska, K; Semeraro, MD; Alonso, N; Herrmann, W The role of bile acid metabolism in bone and muscle: from analytics to mechanisms.
Crit Rev Clin Lab Sci. 2024; 1-19 Doi: 10.1080/10408363.2024.2323132
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2023

Originalarbeit (Zeitschrift)

** Brugger, BA; Neuper, L; Guettler, J; Forstner, D; Wernitznig, S; Kummer, D; Lyssy, F; Feichtinger, J; Krappinger, J; El-Heliebi, A; Bonstingl, L; Moser, G; Rodriguez-Blanco, G; Bachkönig, OA; Gottschalk, B; Gruber, M; Nonn, O; Herse, F; Verlohren, S; Frank, HG; Barapatre, N; Kampfer, C; Fluhr, H; Desoye, G; Gauster, M Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts.
Cell Biosci. 2023; 13(1): 163 Doi: 10.1186/s13578-023-01114-3 [OPEN ACCESS]
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** Ryan, EM; Sadiku, P; Coelho, P; Watts, ER; Zhang, A; Howden, AJM; Sanchez-Garcia, MA; Bewley, M; Cole, J; McHugh, BJ; Vermaelen, W; Ghesquiere, B; Carmeliet, P; Rodriguez, Blanco, G; Von, Kriegsheim, A; Sanchez, Y; Rumsey, W; Callahan, JF; Cooper, G; Parkinson, N; Baillie, K; Cantrell, DA; McCafferty, J; Choudhury, G; Singh, D; Dockrell, DH; Whyte, MKB; Walmsley, SR NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease.
Am J Respir Crit Care Med. 2023; 207(8):998-1011 Doi: 10.1164/rccm.202203-0482OC [OPEN ACCESS]
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** Wolfschluckner, V; Obermüller, B; Horvath, A; Rodriguez-Blanco, G; Fuchs, P; Miekisch, W; Mittl, B; Flucher, C; Till, H; Singer, G Metabolomic Alterations of Volatile Organic Compounds and Bile Acids as Biomarkers of Microbial Shifts in a Murine Model of Short Bowel Syndrome.
Nutrients. 2023; 15(23): Doi: 10.3390/nu15234949 [OPEN ACCESS]
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2022

Originalarbeit (Zeitschrift)

** Almanza, A; Mnich, K; Blomme, A; Robinson, CM; Rodriguez-Blanco, G; Kierszniowska, S; McGrath, EP; Le, Gallo, M; Pilalis, E; Swinnen, JV; Chatziioannou, A; Chevet, E; Gorman, AM; Samali, A Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer.
Nat Commun. 2022; 13(1): 2493 Doi: 10.1038/s41467-022-30159-0 [OPEN ACCESS]
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** Blomme, A; Peter, C; Mui, E; Rodriguez, Blanco, G; An, N; Mason, LM; Jamieson, LE; McGregor, GH; Lilla, S; Ntala, C; Patel, R; Thiry, M; Kung, SHY; Leclercq, M; Ford, CA; Rushworth, LK; McGarry, DJ; Mason, S; Repiscak, P; Nixon, C; Salji, MJ; Markert, E; MacKay, GM; Kamphorst, JJ; Graham, D; Faulds, K; Fazli, L; Gleave, ME; Avezov, E; Edwards, J; Yin, H; Sumpton, D; Blyth, K; Close, P; Murphy, DJ; Zanivan, S; Leung, HY THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer.
EMBO Mol Med. 2022; 14(3): e14764 Doi: 10.15252/emmm.202114764 [OPEN ACCESS]
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** Edwards-Hicks, J; Su, H; Mangolini, M; Yoneten, KK; Wills, J; Rodriguez-Blanco, G; Young, C; Cho, K; Barker, H; Muir, M; Guerrieri, AN; Li, XF; White, R; Manasterski, P; Mandrou, E; Wills, K; Chen, J; Abraham, E; Sateri, K; Qian, BZ; Bankhead, P; Arends, M; Gammoh, N; von, Kriegsheim, A; Patti, GJ; Sims, AH; Acosta, JC; Brunton, V; Kranc, KR; Christophorou, M; Pearce, EL; Ringshausen, I; Finch, AJ MYC sensitises cells to apoptosis by driving energetic demand.
Nat Commun. 2022; 13(1): 4674 Doi: 10.1038/s41467-022-32368-z [OPEN ACCESS]
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2021

Originalarbeit (Zeitschrift)

** Eckrich, J; Frenis, K; Rodriguez-Blanco, G; Ruan, Y; Jiang, S; Bayo, Jimenez, MT; Kuntic, M; Oelze, M; Hahad, O; Li, H; Gericke, A; Steven, S; Strieth, S; von, Kriegsheim, A; Münzel, T; Ernst, BP; Daiber, A Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice.
Redox Biol. 2021; 46: 102063 Doi: 10.1016/j.redox.2021.102063 [OPEN ACCESS]
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** Eckrich, J; Ruan, Y; Jiang, S; Frenis, K; Rodriguez-Blanco, G; Maas, AP; Jimenez, MTB; Kuntic, M; Oelze, M; Hahad, O; Li, H; Steven, S; Strieth, S; von, Kriegsheim, A; Münzel, T; Daiber, A; Gericke, A; Ernst, BP In vivo analysis of noise dependent activation of white blood cells and microvascular dysfunction in mice.
MethodsX. 2021; 8: 101540 Doi: 10.1016/j.mex.2021.101540 [OPEN ACCESS]
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** Marco, S; Neilson, M; Moore, M; Perez-Garcia, A; Hall, H; Mitchell, L; Lilla, S; Blanco, GR; Hedley, A; Zanivan, S; Norman, JC Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion.
Nat Commun. 2021; 12(1):6829 Doi: 10.1038/s41467-021-26839-y [OPEN ACCESS]
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** Martinez, RS; Salji, MJ; Rushworth, L; Ntala, C; Rodriguez, Blanco, G; Hedley, A; Clark, W; Peixoto, P; Hervouet, E; Renaude, E; Kung, SHY; Galbraith, LCA; Nixon, C; Lilla, S; MacKay, GM; Fazli, L; Gaughan, L; Sumpton, D; Gleave, ME; Zanivan, S; Blomme, A; Leung, HY SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer.
Cancer Res. 2021; 81(13):3664-3678 Doi: 10.1158/0008-5472.CAN-20-3694
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** Najumudeen, AK; Ceteci, F; Fey, SK; Hamm, G; Steven, RT; Hall, H; Nikula, CJ; Dexter, A; Murta, T; Race, AM; Sumpton, D; Vlahov, N; Gay, DM; Knight, JRP; Jackstadt, R; Leach, JDG; Ridgway, RA; Johnson, ER; Nixon, C; Hedley, A; Gilroy, K; Clark, W; Malla, SB; Dunne, PD; Rodriguez-Blanco, G; Critchlow, SE; Mrowinska, A; Malviya, G; Solovyev, D; Brown, G; Lewis, DY; Mackay, GM; Strathdee, D; Tardito, S; Gottlieb, E; Takats, Z; Barry, ST; Goodwin, RJA; Bunch, J; Bushell, M; Campbell, AD; Sansom, OJ, , CRUK, Rosetta, Grand, Challenge, Consortium The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Nat Genet. 2021; 53(1):16-26 Doi: 10.1038/s41588-020-00753-3
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** Reyes, L; A, Sanchez-Garcia, M; Morrison, T; Howden, AJM; Watts, ER; Arienti, S; Sadiku, P; Coelho, P; Mirchandani, AS; Zhang, A; Hope, D; Clark, SK; Singleton, J; Johnston, S; Grecian, R; Poon, A; McNamara, S; Harper, I; Fourman, MH; Brenes, AJ; Pathak, S; Lloyd, A; Blanco, GR; von, Kriegsheim, A; Ghesquiere, B; Vermaelen, W; Cologna, CT; Dhaliwal, K; Hirani, N; Dockrell, DH; Whyte, MKB; Griffith, D; Cantrell, DA; Walmsley, SR -------A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS--.
Wellcome Open Res. 2021; 6:38 Doi: 10.12688/wellcomeopenres.16584.2 [OPEN ACCESS]
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** Ryan, DG; Yang, M; Prag, HA; Blanco, GR; Nikitopoulou, E; Segarra-Mondejar, M; Powell, CA; Young, T; Burger, N; Miljkovic, JL; Minczuk, M; Murphy, MP; von, Kriegsheim, A; Frezza, C Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism.
Elife. 2021; 10: Doi: 10.7554/eLife.72593 [OPEN ACCESS]
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** Thorne, LS; Rochford, G; Williams, TD; Southam, AD; Rodriguez-Blanco, G; Dunn, WB; Hodges, NJ Cytoglobin protects cancer cells from apoptosis by regulation of mitochondrial cardiolipin.
Sci Rep. 2021; 11(1): 985 Doi: 10.1038/s41598-020-79830-w [OPEN ACCESS]
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** Wang-Kan, X; Rodríguez-Blanco, G; Southam, AD; Winder, CL; Dunn, WB; Ivens, A; Piddock, LJV Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium.
mBio. 2021; 12(2): Doi: 10.1128/mBio.00109-21 [OPEN ACCESS]
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** Watts, ER; Howden, AJ; Morrison, T; Sadiku, P; Hukelmann, J; von, Kriegsheim, A; Ghesquiere, B; Murphy, F; Mirchandani, AS; Humphries, DC; Grecian, R; Ryan, EM; Coelho, P; Blanco, GR; Plant, TM; Dickinson, RS; Finch, A; Vermaelen, W; Cantrell, DA; Whyte, MK; Walmsley, SR Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism.
J Clin Invest. 2021; 131(10): Doi: 10.1172/JCI134073 [OPEN ACCESS]
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Korrektur

** Sadiku, P; Willson, JA; Ryan, EM; Sammut, D; Coelho, P; Watts, ER; Grecian, R; Young, JM; Bewley, M; Arienti, S; Mirchandani, AS; Sanchez, Garcia, MA; Morrison, T; Zhang, A; Reyes, L; Griessler, T; Jheeta, P; Paterson, GG; Graham, CJ; Thomson, JP; Baillie, K; Thompson, AAR; Morgan, JM; Acosta-Sanchez, A; Dardé, VM; Duran, J; Guinovart, JJ; Rodriguez-Blanco, G; Von, Kriegsheim, A; Meehan, RR; Mazzone, M; Dockrell, DH; Ghesquiere, B; Carmeliet, P; Whyte, MKB; Walmsley, SR Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis.
Cell Metab. 2021; 33(5): 1062-1064. Doi: 10.1016/j.cmet.2021.03.018 [OPEN ACCESS]
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2020

Originalarbeit (Zeitschrift)

** Blomme, A; Ford, CA; Mui, E; Patel, R; Ntala, C; Jamieson, LE; Planque, M; McGregor, GH; Peixoto, P; Hervouet, E; Nixon, C; Salji, M; Gaughan, L; Markert, E; Repiscak, P; Sumpton, D; Blanco, GR; Lilla, S; Kamphorst, JJ; Graham, D; Faulds, K; MacKay, GM; Fendt, SM; Zanivan, S; Leung, HY 2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.
Nat Commun. 2020; 11(1):2508 Doi: 10.1038/s41467-020-16126-7 [OPEN ACCESS]
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** Oizel, K; Tait-Mulder, J; Fernandez-de-Cossio-Diaz, J; Pietzke, M; Brunton, H; Lilla, S; Dhayade, S; Athineos, D; Blanco, GR; Sumpton, D; Mackay, GM; Blyth, K; Zanivan, SR; Meiser, J; Vazquez, A Formate induces a metabolic switch in nucleotide and energy metabolism.
Cell Death Dis. 2020; 11(5):310 Doi: 10.1038/s41419-020-2523-z [OPEN ACCESS]
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** Roca-Portoles, A; Rodriguez-Blanco, G; Sumpton, D; Cloix, C; Mullin, M; Mackay, GM; O'Neill, K; Lemgruber, L; Luo, X; Tait, SWG Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition.
Cell Death Dis. 2020; 11(8): 616 Doi: 10.1038/s41419-020-02867-2 [OPEN ACCESS]
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** Wilkinson, DJ; Rodriguez-Blanco, G; Dunn, WB; Phillips, BE; Williams, JP; Greenhaff, PL; Smith, K; Gallagher, IJ; Atherton, PJ Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing.
Aging (Albany NY). 2020; 12(13): 12517-12533. Doi: 10.18632/aging.103513 [OPEN ACCESS]
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Kommentar

** McGregor, GH; Campbell, AD; Fey, SK; Tumanov, S; Sumpton, D; Blanco, GR; Mackay, G; Nixon, C; Vazquez, A; Sansom, OJ; Kamphorst, JJ Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor Response.
Cancer Res. 2020; 80(2):175-188 Doi: 10.1158/0008-5472.CAN-19-0644
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2019

Originalarbeit (Zeitschrift)

** Duijvesz, D; Rodriguez-Blanco, G; Hoogland, AM; Verhoef, EI; Dekker, LJ; Roobol, MJ; van, Leenders, GJLH; Luider, TM; Jenster, G Differential tissue expression of extracellular vesicle-derived proteins in prostate cancer.
Prostate. 2019; 79(9): 1032-1042. Doi: 10.1002/pros.23813 [OPEN ACCESS]
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** Jeffery, HC; Hunter, S; Humphreys, EH; Bhogal, R; Wawman, RE; Birtwistle, J; Atif, M; Bagnal, CJ; Rodriguez, Blanco, G; Richardson, N; Warner, S; Dunn, WB; Afford, SC; Adams, DH; Oo, YH Bidirectional Cross-Talk between Biliary Epithelium and Th17 Cells Promotes Local Th17 Expansion and Bile Duct Proliferation in Biliary Liver Diseases.
J Immunol. 2019; 203(5): 1151-1159. Doi: 10.4049/jimmunol.1800455 [OPEN ACCESS]
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** Najdekr, L; Blanco, GR; Dunn, WB Collection of Untargeted Metabolomic Data for Mammalian Urine Applying HILIC and Reversed Phase Ultra Performance Liquid Chromatography Methods Coupled to a Q Exactive Mass Spectrometer.
Methods Mol Biol. 2019; 1996: 1-15. Doi: 10.1007/978-1-4939-9488-5_1
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2018

Originalarbeit (Zeitschrift)

** Chortis, V; Taylor, AE; Doig, CL; Walsh, MD; Meimaridou, E; Jenkinson, C; Rodriguez-Blanco, G; Ronchi, CL; Jafri, A; Metherell, LA; Hebenstreit, D; Dunn, WB; Arlt, W; Foster, PA Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma.
Endocrinology. 2018; 159(8): 2836-2849. Doi: 10.1210/en.2018-00014 [OPEN ACCESS]
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** Lyall, MJ; Cartier, J; Thomson, JP; Cameron, K; Meseguer-Ripolles, J; O'Duibhir, E; Szkolnicka, D; Villarin, BL; Wang, Y; Blanco, GR; Dunn, WB; Meehan, RR; Hay, DC; Drake, AJ Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells.
Philos Trans R Soc Lond B Biol Sci. 2018; 373(1750): Doi: 10.1098/rstb.2017.0362 [OPEN ACCESS]
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** Rodríguez-Blanco, G; Zeneyedpour, L; Duijvesz, D; Hoogland, AM; Verhoef, EI; Kweldam, CF; Burgers, PC; Smitt, PS; Bangma, CH; Jenster, G; van, Leenders, GJLH; Dekker, LJM; Luider, TM Tissue proteomics outlines AGR2 AND LOX5 as markers for biochemical recurrence of prostate cancer.
Oncotarget. 2018; 9(92): 36444-36456. Doi: 10.18632/oncotarget.26342 [OPEN ACCESS]
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2017

Originalarbeit (Zeitschrift)

** Lawson, TN; Weber, RJ; Jones, MR; Chetwynd, AJ; Rodrı, Guez-Blanco, G; Di, Guida, R; Viant, MR; Dunn, WB msPurity: Automated Evaluation of Precursor Ion Purity for Mass Spectrometry-Based Fragmentation in Metabolomics.
Anal Chem. 2017; 89(4): 2432-2439. Doi: 10.1021/acs.analchem.6b04358
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** Partolina, M; Thoms, HC; MacLeod, KG; Rodriguez-Blanco, G; Clarke, MN; Venkatasubramani, AV; Beesoo, R; Larionov, V; Neergheen-Bhujun, VS; Serrels, B; Kimura, H; Carragher, NO; Kagansky, A Global histone modification fingerprinting in human cells using epigenetic reverse phase protein array.
Cell Death Discov. 2017; 3: 16077 Doi: 10.1038/cddiscovery.2016.77 [OPEN ACCESS]
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Übersichtsarbeit

** Chetwynd, AJ; Dunn, WB; Rodriguez-Blanco, G Collection and Preparation of Clinical Samples for Metabolomics.
Adv Exp Med Biol. 2017; 965: 19-44. Doi: 10.1007/978-3-319-47656-8_2
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2014

Originalarbeit (Zeitschrift)

** Rodríguez-Blanco, G; Burgers, PC; Dekker, LJ; Ijzermans, JJ; Wildhagen, MF; Schenk-Braat, EA; Bangma, CH; Jenster, G; Luider, TM Serum levels of arachidonic acid metabolites change during prostate cancer progression.
Prostate. 2014; 74(6): 618-27. Doi: 10.1002/pros.22779
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Kurzbericht/Letter

** Rodríguez-Blanco, G; Burgers, PC; Dekker, LJ; Vredenbregt-van, den, Berg, MS; Ijzermans, JN; Schenk-Braat, EA; Jenster, G; Luider, TM Serum kynurenine/tryptophan ratio is not a potential marker for detecting prostate cancer.
Clin Biochem. 2014; 47(13-14): 1347-8. Doi: 10.1016/j.clinbiochem.2014.05.001
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2013

Originalarbeit (Zeitschrift)

** Rodríguez-Blanco, G; Jobst, KJ; Luider, TM; Terlouw, JK; Burgers, PC Generation and Dissociation of RCOOCaCl2 - and other Carboxylate-Substituted Superhalogens: CO2 Capture and Implications for Structure Analysis.
Chempluschem. 2013; 78(9): 1184-1189. Doi: 10.1002/cplu.201300161
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