Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Eichmann Thomas |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Bordag, N; Nagy, BM; Zügner, E; Ludwig, H; Foris, V; Nagaraj, C; Biasin, V; Kovacs, G; Kneidinger, N; Bodenhofer, U; Magnes, C; Maron, BA; Ulrich, S; Lange, TJ; Eichmann, TO; Hoetzenecker, K; Pieber, T; Olschewski, H; Olschewski, A Lipid Ratios for Diagnosis and Prognosis of Pulmonary Hypertension.
Am J Respir Crit Care Med. 2025;
PubMed

 

** Zandl-Lang, M; Züllig, T; Holzer, M; Eichmann, TO; Darnhofer, B; Schwerin-Nagel, A; Zobel, J; Haidl, H; Biebl, A; Köfeler, H; Plecko, B Multi-omics profiling in spinal muscular atrophy (SMA): investigating lipid and metabolic alterations through longitudinal CSF analysis of Nusinersen-treated patients.
J Neurol. 2025; 272(3): 183 Doi: 10.1007/s00415-025-12909-4 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2024

Originalarbeit (Zeitschrift)

** Akhmetshina, A; Bianco, V; Bradić, I; Korbelius, M; Pirchheim, A; Kuentzel, KB; Eichmann, TO; Hinteregger, H; Kolb, D; Habisch, H; Liesinger, L; Madl, T; Sattler, W; Radović, B; Sedej, S; Birner-Gruenberger, R; Vujić, N; Kratky, D Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Mol Metab. 2024; 79:101869 Doi: 10.1016/j.molmet.2023.101869 [OPEN ACCESS]
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** Haitzmann, T; Schindlmaier, K; Frech, T; Mondal, A; Bubalo, V; Konrad, B; Bluemel, G; Stiegler, P; Lackner, S; Hrzenjak, A; Eichmann, T; Köfeler, HC; Leithner, K Serine synthesis and catabolism in starved lung cancer and primary bronchial epithelial cells.
Cancer Metab. 2024; 12(1): 9 Doi: 10.1186/s40170-024-00337-3 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Zeitschrift)

** Runtsch, M; Kindler, O; Eichmann, T; Santiso, A; Maitz, K; Brcic, L; Lindenmann, J; Kargl, J The tumor microenvironment drives mitochondrial metabolic reprogramming in neutrophils during non-small cell lung cancer
EUR J IMMUNOL. 2024; 54: 176-176.-7th European Conference of Immunology; SEP 01-04, 2024; Dublin, IRELAND. [Oral Communication]
Web of Science

 

2023

Originalarbeit (Zeitschrift)

** Berger, N; van, der, Wel, T; Hirschmugl, B; Baernthaler, T; Gindlhuber, J; Fawzy, N; Eichmann, T; Birner-Gruenberger, R; Zimmermann, R; van, der, Stelt, M; Wadsack, C Inhibition of diacylglycerol lipase β modulates lipid and endocannabinoid levels in the ex vivo human placenta.
Front Endocrinol (Lausanne). 2023; 14: 1092024 Doi: 10.3389/fendo.2023.1092024 [OPEN ACCESS]
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** Goeritzer, M; Kuentzel, KB; Beck, S; Korbelius, M; Rainer, S; Bradić, I; Kolb, D; Mussbacher, M; Schrottmaier, WC; Assinger, A; Schlagenhauf, A; Rost, R; Gottschalk, B; Eichmann, TO; Züllig, T; Graier, WF; Vujić, N; Kratky, D Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice.
Int J Mol Sci. 2023; 24(4): 3116 Doi: 10.3390/ijms24043116 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Kotzbeck, P; Taschler, U; Haudum, C; Foessl, I; Schoiswohl, G; Boulgaropoulos, B; Bounab, K; Einsiedler, J; Pajed, L; Tilp, A; Schwarz, A; Eichmann, TO; Obermayer-Pietsch, B; Giordano, A; Cinti, S; Zechner, R; Pieber, TR Rosiglitazone Reverses Inflammation in Epididymal White Adipose Tissue in Hormone-Sensitive Lipase-Knockout Mice.
J Lipid Res. 2023; 64(1):100305 Doi: 10.1016/j.jlr.2022.100305 [OPEN ACCESS]
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** Liebscher, G; Vujic, N; Schreiber, R; Heine, M; Krebiehl, C; Duta-Mare, M; Lamberti, G; de, Smet, CH; Hess, MW; Eichmann, TO; Hölzl, S; Scheja, L; Heeren, J; Kratky, D; Huber, LA The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
Mol Metab. 2023; 71: 101705 Doi: 10.1016/j.molmet.2023.101705 [OPEN ACCESS]
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2022

Originalarbeit (Zeitschrift)

** Goeritzer, M; Schlager, S; Kuentzel, KB; Vujić, N; Korbelius, M; Rainer, S; Kolb, D; Mussbacher, M; Salzmann, M; Schrottmaier, WC; Assinger, A; Schlagenhauf, A; Madreiter-Sokolowski, CT; Blass, S; Eichmann, TO; Graier, WF; Kratky, D Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo.
Cells. 2022; 11(5): Doi: 10.3390/cells11050850 [OPEN ACCESS]
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** Kanti, MM; Striessnig-Bina, I; Wieser, BI; Schauer, S; Leitinger, G; Eichmann, TO; Schweiger, M; Winkler, M; Winter, E; Lana, A; Kufferath, I; Marsh, LM; Kwapiszewska, G; Zechner, R; Hoefler, G; Vesely, PW Adipose triglyceride lipase-mediated lipid catabolism is essential for bronchiolar regeneration.
JCI Insight. 2022; 7(9): Doi: 10.1172/jci.insight.149438 [OPEN ACCESS]
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** Vigor, C; Züllig, T; Eichmann, TO; Oger, C; Zhou, B; Rechberger, GN; Hilsberg, L; Trötzmüller, M; Pellegrino, RM; Alabed, HBR; Hartler, J; Wolinski, H; Galano, JM; Durand, T; Spener, F α-Linolenic acid and product octadecanoids in Styrian pumpkin seeds and oils: How processing impacts lipidomes of fatty acid, triacylglycerol and oxylipin molecular structures.
Food Chem. 2022; 371:131194 Doi: 10.1016/j.foodchem.2021.131194 [OPEN ACCESS]
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2021

Originalarbeit (Zeitschrift)

** Grbčić, P; Eichmann, TO; Kraljević, Pavelić, S; Sedić, M The Sphingosine Kinase 2 Inhibitor ABC294640 Restores the Sensitivity of BRAFV600E Mutant Colon Cancer Cells to Vemurafenib by Reducing AKT-Mediated Expression of Nucleophosmin and Translationally-Controlled Tumour Protein.
Int J Mol Sci. 2021; 22(19): Doi: 10.3390/ijms221910767 [OPEN ACCESS]
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** Hundahl, C; Kotzbeck, P; Burm, HB; Christiansen, SH; Torz, L; Helge, AW; Madsen, MP; Ratner, C; Serup, AK; Thompson, JJ; Eichmann, TO; Pers, TH; Woldbye, DPD; Piomelli, D; Kiens, B; Zechner, R; Skov, LJ; Holst, B Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis.
Mol Metab. 2021; 47:101174 Doi: 10.1016/j.molmet.2021.101174 [OPEN ACCESS]
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** Pajed, L; Taschler, U; Tilp, A; Hofer, P; Kotzbeck, P; Kolleritsch, S; Radner, FPW; Pototschnig, I; Wagner, C; Schratter, M; Eder, S; Huetter, S; Schreiber, R; Haemmerle, G; Eichmann, TO; Schweiger, M; Hoefler, G; Kershaw, EE; Lass, A; Schoiswohl, G Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Commun Biol. 2021; 4(1):323 Doi: 10.1038/s42003-021-01858-z [OPEN ACCESS]
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** Pavel, P; Leman, G; Hermann, M; Ploner, C; Eichmann, TO; Minzaghi, D; Radner, FPW; Del, Frari, B; Gruber, R; Dubrac, S Peroxisomal Fatty Acid Oxidation and Glycolysis Are Triggered in Mouse Models of Lesional Atopic Dermatitis.
JID Innov. 2021; 1(3): 100033 Doi: 10.1016/j.xjidi.2021.100033 [OPEN ACCESS]
PubMed PUBMED Central FullText FullText_MUG

 

** Trakaki, A; Wolf, P; Weger, W; Eichmann, TO; Scharnagl, H; Stadler, JT; Salmhofer, W; Knuplez, E; Holzer, M; Marsche, G Biological anti-psoriatic therapy profoundly affects high-density lipoprotein function.
Biochim Biophys Acta Mol Cell Biol Lipids. 2021; 1866(7):158943 Doi: 10.1016/j.bbalip.2021.158943 [OPEN ACCESS]
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Kommentar

** Köfeler, HC; Eichmann, TO; Ahrends, R; Bowden, JA; Danne-Rasche, N; Dennis, EA; Fedorova, M; Griffiths, WJ; Han, X; Hartler, J; Holčapek, M; Jirásko, R; Koelmel, JP; Ejsing, CS; Liebisch, G; Ni, Z; O'Donnell, VB; Quehenberger, O; Schwudke, D; Shevchenko, A; Wakelam, MJO; Wenk, MR; Wolrab, D; Ekroos, K Quality control requirements for the correct annotation of lipidomics data.
Nat Commun. 2021; 12(1):4771 Doi: 10.1038/s41467-021-24984-y [OPEN ACCESS]
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2020

Originalarbeit (Zeitschrift)

** Anand, R; Kondadi, AK; Meisterknecht, J; Golombek, M; Nortmann, O; Riedel, J; Peifer-Weiß, L; Brocke-Ahmadinejad, N; Schlütermann, D; Stork, B; Eichmann, TO; Wittig, I; Reichert, AS MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes.
Life Sci Alliance. 2020; 3(10): Doi: 10.26508/lsa.202000711 [OPEN ACCESS]
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** Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21031143 [OPEN ACCESS]
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** Grabner, GF; Fawzy, N; Schreiber, R; Pusch, LM; Bulfon, D; Koefeler, H; Eichmann, TO; Lass, A; Schweiger, M; Marsche, G; Schoiswohl, G; Taschler, U; Zimmermann, R Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice.
J Lipid Res. 2020; 61(7):995-1003 Doi: 10.1194/jlr.RA119000516 [OPEN ACCESS]
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** Kolleritsch, S; Kien, B; Schoiswohl, G; Diwoky, C; Schreiber, R; Heier, C; Maresch, LK; Schweiger, M; Eichmann, TO; Stryeck, S; Krenn, P; Tomin, T; Schittmayer, M; Kolb, D; Rülicke, T; Hoefler, G; Wolinski, H; Madl, T; Birner-Gruenberger, R; Haemmerle, G Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.
Cardiovasc Res. 2020; 116(2):339-352 Doi: 10.1093/cvr/cvz119 [OPEN ACCESS]
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** Savini, F; Loffredo, MR; Troiano, C; Bobone, S; Malanovic, N; Eichmann, TO; Caprio, L; Canale, VC; Park, Y; Mangoni, ML; Stella, L Binding of an antimicrobial peptide to bacterial cells: Interaction with different species, strains and cellular components.
Biochim Biophys Acta Biomembr. 2020; 1862(8): 183291 Doi: 10.1016/j.bbamem.2020.183291
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** Tang, Z; Xie, H; Heier, C; Huang, J; Zheng, Q; Eichmann, TO; Schoiswohl, G; Ni, J; Zechner, R; Ni, S; Hao, H Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis.
EBioMedicine. 2020; 53: 102696 Doi: 10.1016/j.ebiom.2020.102696 [OPEN ACCESS]
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2019

Originalarbeit (Zeitschrift)

** Bhat, VK; Bernhart, E; Plastira, I; Fan, K; Ghaffari-Tabrizi-Wizsy, N; Wadsack, C; Rechberger, G; Eichmann, T; Asslaber, M; Spassova, I; Verhaegen, ME; Malle, E; Becker, JC; Sattler, W Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.
J Invest Dermatol. 2019; 139(4):807-817 Doi: 10.1016/j.jid.2018.10.024 [OPEN ACCESS]
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** Grabner, GF; Fawzy, N; Pribasnig, MA; Trieb, M; Taschler, U; Holzer, M; Schweiger, M; Wolinski, H; Kolb, D; Horvath, A; Breinbauer, R; Rülicke, T; Rabl, R; Lass, A; Stadlbauer, V; Hutter-Paier, B; Stauber, RE; Fickert, P; Zechner, R; Marsche, G; Eichmann, TO; Zimmermann, R Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans.
J Lipid Res. 2019; 60(5):1020-1031 Doi: 10.1194/jlr.M093351 [OPEN ACCESS]
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** Hehlert, P; Hofferek, V; Heier, C; Eichmann, TO; Riedel, D; Rosenberg, J; Takaćs, A; Nagy, HM; Oberer, M; Zimmermann, R; Kühnlein, RP The α/β-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila.
J Lipid Res. 2019; 60(8): 1365-1378. Doi: 10.1194/jlr.M092817 [OPEN ACCESS]
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** Hörer, S; Marrakchi, S; Radner, FPW; Zolles, G; Heinz, L; Eichmann, TO; Has, C; Salavei, P; Mahfoudh, N; Turki, H; Zimmer, AD; Fischer, J A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation.
J Invest Dermatol. 2019; 139(10): 2154-2163.e5. Doi: 10.1016/j.jid.2019.04.015
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** Maresch, LK; Benedikt, P; Feiler, U; Eder, S; Zierler, KA; Taschler, U; Kolleritsch, S; Eichmann, TO; Schoiswohl, G; Leopold, C; Wieser, BI; Lackner, C; Rülicke, T; van, Klinken, J; Kratky, D; Moustafa, T; Hoefler, G; Haemmerle, G Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
Hepatol Commun. 2019; 3(2):227-245 Doi: 10.1002/hep4.1292 [OPEN ACCESS]
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** Pajed, L; Wagner, C; Taschler, U; Schreiber, R; Kolleritsch, S; Fawzy, N; Pototschnig, I; Schoiswohl, G; Pusch, LM; Wieser, BI; Vesely, P; Hoefler, G; Eichmann, TO; Zimmermann, R; Lass, A Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
J Biol Chem. 2019; 294(23):9118-9133 Doi: 10.1074/jbc.RA118.007201 [OPEN ACCESS]
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** Schilcher, I; Ledinski, G; Radulović, S; Hallström, S; Eichmann, T; Madl, T; Zhang, F; Leitinger, G; Kolb-Lenz, D; Darnhofer, B; Birner-Gruenberger, R; Wadsack, C; Kratky, D; Marsche, G; Frank, S; Cvirn, G Endothelial lipase increases antioxidative capacity of high-density lipoprotein.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1363-1374 Doi: 10.1016/j.bbalip.2019.06.011 [OPEN ACCESS]
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** Trakaki, A; Sturm, GJ; Pregartner, G; Scharnagl, H; Eichmann, TO; Trieb, M; Knuplez, E; Holzer, M; Stadler, JT; Heinemann, A; Sturm, EM; Marsche, G Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1280-1292 Doi: 10.1016/j.bbalip.2019.06.007 [OPEN ACCESS]
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** Werthebach, M; Stewart, FA; Gahlen, A; Mettler-Altmann, T; Akhtar, I; Maas-Enriquez, K; Droste, A; Eichmann, TO; Poschmann, G; Stühler, K; Beller, M Control of Drosophila Growth and Survival by the Lipid Droplet-Associated Protein CG9186/Sturkopf.
Cell Rep. 2019; 26(13): 3726-3740.e7. Doi: 10.1016/j.celrep.2019.02.110
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Kurzbericht/Letter

** Trieb, M; Wolf, P; Knuplez, E; Weger, W; Schuster, C; Peinhaupt, M; Holzer, M; Trakaki, A; Eichmann, T; Lass, A; Wadsack, C; Schuligoi, R; Heinemann, A; Marsche, G Abnormal composition and function of high-density lipoproteins in atopic dermatitis patients.
Allergy. 2019; 74(2):398-402 Doi: 10.1111/all.13620 [OPEN ACCESS]
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2018

Originalarbeit (Zeitschrift)

** D'Souza, K; Nzirorera, C; Cowie, AM; Varghese, GP; Trivedi, P; Eichmann, TO; Biswas, D; Touaibia, M; Morris, AJ; Aidinis, V; Kane, DA; Pulinilkunnil, T; Kienesberger, PC Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism.
J Lipid Res. 2018; 59(10): 1805-1817. Doi: 10.1194/jlr.M082008 [OPEN ACCESS]
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** Dyar, KA; Hubert, MJ; Mir, AA; Ciciliot, S; Lutter, D; Greulich, F; Quagliarini, F; Kleinert, M; Fischer, K; Eichmann, TO; Wright, LE; Peña, Paz, MI; Casarin, A; Pertegato, V; Romanello, V; Albiero, M; Mazzucco, S; Rizzuto, R; Salviati, L; Biolo, G; Blaauw, B; Schiaffino, S; Uhlenhaut, NH Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
PLoS Biol. 2018; 16(8): e2005886 Doi: 10.1371/journal.pbio.2005886 [OPEN ACCESS]
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** Elentner, A; Schmuth, M; Yannoutsos, N; Eichmann, TO; Gruber, R; Radner, FPW; Hermann, M; Del, Frari, B; Dubrac, S Epidermal Overexpression of Xenobiotic Receptor PXR Impairs the Epidermal Barrier and Triggers Th2 Immune Response.
J Invest Dermatol. 2018; 138(1): 109-120. Doi: 10.1016/j.jid.2017.07.846 [OPEN ACCESS]
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** Jarc, E; Eichmann, TO; Zimmermann, R; Petan, T Lipidomic data on lipid droplet triglyceride remodelling associated with protection of breast cancer cells from lipotoxic stress.
Data Brief. 2018; 18: 234-240. Doi: 10.1016/j.dib.2018.03.033 [OPEN ACCESS]
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** Jarc, E; Kump, A; Malavašič, P; Eichmann, TO; Zimmermann, R; Petan, T Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress.
Biochim Biophys Acta Mol Cell Biol Lipids. 2018; 1863(3): 247-265. Doi: 10.1016/j.bbalip.2017.12.006
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** Kien, B; Grond, S; Haemmerle, G; Lass, A; Eichmann, TO; Radner, FPW ABHD5 stimulates PNPLA1-mediated ω-O-acylceramide biosynthesis essential for a functional skin permeability barrier.
J Lipid Res. 2018; 59(12): 2360-2367. Doi: 10.1194/jlr.M089771 [OPEN ACCESS]
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** Kohl, P; Zingl, FG; Eichmann, TO; Schild, S Isolation of Outer Membrane Vesicles Including Their Quantitative and Qualitative Analyses.
Methods Mol Biol. 2018; 1839: 117-134. Doi: 10.1007/978-1-4939-8685-9_11
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** Visram, M; Radulovic, M; Steiner, S; Malanovic, N; Eichmann, TO; Wolinski, H; Rechberger, GN; Tehlivets, O Homocysteine regulates fatty acid and lipid metabolism in yeast.
J Biol Chem. 2018; 293(15): 5544-5555. Doi: 10.1074/jbc.M117.809236 [OPEN ACCESS]
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2017

Originalarbeit (Zeitschrift)

** Gao, Y; Layritz, C; Legutko, B; Eichmann, TO; Laperrousaz, E; Moullé, VS; Cruciani-Guglielmacci, C; Magnan, C; Luquet, S; Woods, SC; Eckel, RH; Yi, CX; Garcia-Caceres, C; Tschöp, MH Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity.
Diabetes. 2017; 66(10): 2555-2563. Doi: 10.2337/db16-1278 [OPEN ACCESS]
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** Gao, Y; Vidal-Itriago, A; Kalsbeek, MJ; Layritz, C; García-Cáceres, C; Tom, RZ; Eichmann, TO; Vaz, FM; Houtkooper, RH; van, der, Wel, N; Verhoeven, AJ; Yan, J; Kalsbeek, A; Eckel, RH; Hofmann, SM; Yi, CX Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity.
Cell Rep. 2017; 20(13): 3034-3042. Doi: 10.1016/j.celrep.2017.09.008
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** Grond, S; Eichmann, TO; Dubrac, S; Kolb, D; Schmuth, M; Fischer, J; Crumrine, D; Elias, PM; Haemmerle, G; Zechner, R; Lass, A; Radner, FPW PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.
J Invest Dermatol. 2017; 137(2):394-402 Doi: 10.1016/j.jid.2016.08.036 [OPEN ACCESS]
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** Grond, S; Radner, FPW; Eichmann, TO; Kolb, D; Grabner, GF; Wolinski, H; Gruber, R; Hofer, P; Heier, C; Schauer, S; Rülicke, T; Hoefler, G; Schmuth, M; Elias, PM; Lass, A; Zechner, R; Haemmerle, G Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.
J Invest Dermatol. 2017; 137(2):403-413 Doi: 10.1016/j.jid.2016.09.025 [OPEN ACCESS]
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** Heier, C; Kien, B; Huang, F; Eichmann, TO; Xie, H; Zechner, R; Chang, PA The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain.
J Biol Chem. 2017; 292(46): 19087-19098. Doi: 10.1074/jbc.M117.792978 [OPEN ACCESS]
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** Hofer, DC; Pessentheiner, AR; Pelzmann, HJ; Schlager, S; Madreiter-Sokolowski, CT; Kolb, D; Eichmann, TO; Rechberger, G; Bilban, M; Graier, WF; Kratky, D; Bogner-Strauss, JG Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017; 1862(3):358-368 Doi: 10.1016/j.bbalip.2016.12.009 [OPEN ACCESS]
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** Schweiger, M; Romauch, M; Schreiber, R; Grabner, GF; Hütter, S; Kotzbeck, P; Benedikt, P; Eichmann, TO; Yamada, S; Knittelfelder, O; Diwoky, C; Doler, C; Mayer, N; De, Cecco, W; Breinbauer, R; Zimmermann, R; Zechner, R Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Nat Commun. 2017; 8:14859 Doi: 10.1038/ncomms14859 [OPEN ACCESS]
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** Vujic, N; Korbelius, M; Leopold, C; Duta-Mare, M; Rainer, S; Schlager, S; Goeritzer, M; Kolb, D; Eichmann, TO; Diwoky, C; Zimmer, A; Zimmermann, R; Lass, A; Radovic, B; Kratky, D Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.
Oncotarget. 2017; 8(20):33122-33136 Doi: 10.18632/oncotarget.16529 [OPEN ACCESS]
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2016

Originalarbeit (Zeitschrift)

** Grabner, GF; Eichmann, TO; Wagner, B; Gao, Y; Farzi, A; Taschler, U; Radner, FP; Schweiger, M; Lass, A; Holzer, P; Zinser, E; Tschöp, MH; Yi, CX; Zimmermann, R Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation.
J Biol Chem. 2016; 291(2):913-23 Doi: 10.1074/jbc.M115.683615 [OPEN ACCESS]
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** Grumet, L; Eichmann, TO; Taschler, U; Zierler, KA; Leopold, C; Moustafa, T; Radovic, B; Romauch, M; Yan, C; Du, H; Haemmerle, G; Zechner, R; Fickert, P; Kratky, D; Zimmermann, R; Lass, A Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.
J Biol Chem. 2016; 291(34):17977-87 Doi: 10.1074/jbc.M116.724054 [OPEN ACCESS]
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** Heier, C; Taschler, U; Radulovic, M; Aschauer, P; Eichmann, TO; Grond, S; Wolinski, H; Oberer, M; Zechner, R; Kohlwein, SD; Zimmermann, R Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism.
J Biol Chem. 2016; 291(22):11865-75 Doi: 10.1074/jbc.M115.705541 [OPEN ACCESS]
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** Roier, S; Zingl, FG; Cakar, F; Durakovic, S; Kohl, P; Eichmann, TO; Klug, L; Gadermaier, B; Weinzerl, K; Prassl, R; Lass, A; Daum, G; Reidl, J; Feldman, MF; Schild, S A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.
Nat Commun. 2016; 7:10515 Doi: 10.1038/ncomms10515 [OPEN ACCESS]
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** Tschapalda, K; Zhang, YQ; Liu, L; Golovnina, K; Schlemper, T; Eichmann, TO; Lal-Nag, M; Sreenivasan, U; McLenithan, J; Ziegler, S; Sztalryd, C; Lass, A; Auld, D; Oliver, B; Waldmann, H; Li, Z; Shen, M; Boxer, MB; Beller, M A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics.
EBioMedicine. 2016; 8: 49-59. Doi: 10.1016/j.ebiom.2016.04.014 [OPEN ACCESS]
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** Vujic, N; Schlager, S; Eichmann, TO; Madreiter-Sokolowski, CT; Goeritzer, M; Rainer, S; Schauer, S; Rosenberger, A; Woelfler, A; Doddapattar, P; Zimmermann, R; Hoefler, G; Lass, A; Graier, WF; Radovic, B; Kratky, D Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.
Atherosclerosis. 2016; 244:9-21 Doi: 10.1016/j.atherosclerosis.2015.10.109 [OPEN ACCESS]
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2015

Originalarbeit (Zeitschrift)

** Eichmann, TO; Grumet, L; Taschler, U; Hartler, J; Heier, C; Woblistin, A; Pajed, L; Kollroser, M; Rechberger, G; Thallinger, GG; Zechner, R; Haemmerle, G; Zimmermann, R; Lass, A ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6.
J Lipid Res. 2015; 56(10):1972-84 Doi: 10.1194/jlr.M062372 [OPEN ACCESS]
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** Heier, C; Radner, FP; Moustafa, T; Schreiber, R; Grond, S; Eichmann, TO; Schweiger, M; Schmidt, A; Cerk, IK; Oberer, M; Theussl, HC; Wojciechowski, J; Penninger, JM; Zimmermann, R; Zechner, R G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.
J Biol Chem. 2015; 290(43):26141-50 Doi: 10.1074/jbc.M115.671842 [OPEN ACCESS]
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** Jaeger, D; Schoiswohl, G; Hofer, P; Schreiber, R; Schweiger, M; Eichmann, TO; Pollak, NM; Poecher, N; Grabner, GF; Zierler, KA; Eder, S; Kolb, D; Radner, FP; Preiss-Landl, K; Lass, A; Zechner, R; Kershaw, EE; Haemmerle, G Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.
J Hepatol. 2015; 63(2):437-45 Doi: 10.1016/j.jhep.2015.02.035 [OPEN ACCESS]
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** Pribasnig, MA; Mrak, I; Grabner, GF; Taschler, U; Knittelfelder, O; Scherz, B; Eichmann, TO; Heier, C; Grumet, L; Kowaliuk, J; Romauch, M; Holler, S; Anderl, F; Wolinski, H; Lass, A; Breinbauer, R; Marsche, G; Brown, JM; Zimmermann, R α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate.
J Biol Chem. 2015; 290(50):29869-81 Doi: 10.1074/jbc.M115.669168 [OPEN ACCESS]
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** Schlager, S; Goeritzer, M; Jandl, K; Frei, R; Vujic, N; Kolb, D; Strohmaier, H; Dorow, J; Eichmann, TO; Rosenberger, A; Wölfler, A; Lass, A; Kershaw, EE; Ceglarek, U; Dichlberger, A; Heinemann, A; Kratky, D Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.
J Leukoc Biol. 2015; 98(5):837-50 Doi: 10.1189/jlb.3A0515-206R [OPEN ACCESS]
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** Taschler, U; Eichmann, TO; Radner, FP; Grabner, GF; Wolinski, H; Storr, M; Lass, A; Schicho, R; Zimmermann, R Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity.
Br J Pharmacol. 2015; 172(17):4419-29 Doi: 10.1111/bph.13224 [OPEN ACCESS]
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Übersichtsarbeit

** Eichmann, TO; Lass, A DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling.
Cell Mol Life Sci. 2015; 72(20): 3931-52. Doi: 10.1007/s00018-015-1982-3 [OPEN ACCESS]
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2014

Originalarbeit (Zeitschrift)

** Knittelfelder, OL; Weberhofer, BP; Eichmann, TO; Kohlwein, SD; Rechberger, GN A versatile ultra-high performance LC-MS method for lipid profiling.
J Chromatogr B Analyt Technol Biomed Life Sci. 2014; 951-952: 119-28. Doi: 10.1016/j.jchromb.2014.01.011 [OPEN ACCESS]
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** Schweiger, M; Eichmann, TO; Taschler, U; Zimmermann, R; Zechner, R; Lass, A Measurement of lipolysis.
Methods Enzymol. 2014; 538:171-93 Doi: 10.1016/B978-0-12-800280-3.00010-4 [OPEN ACCESS]
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** Sparks, LM; Bosma, M; Brouwers, B; van, de, Weijer, T; Bilet, L; Schaart, G; Moonen-Kornips, E; Eichmann, TO; Lass, A; Hesselink, MKC; Schrauwen, P Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes.
Diabetes. 2014; 63(5): 1583-1593. Doi: 10.2337/db13-1123 [OPEN ACCESS]
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2013

Originalarbeit (Zeitschrift)

** Mayer, N; Schweiger, M; Romauch, M; Grabner, GF; Eichmann, TO; Fuchs, E; Ivkovic, J; Heier, C; Mrak, I; Lass, A; Höfler, G; Fledelius, C; Zechner, R; Zimmermann, R; Breinbauer, R Development of small-molecule inhibitors targeting adipose triglyceride lipase.
Nat Chem Biol. 2013; 9(12):785-7 Doi: 10.1038/nchembio.1359 [OPEN ACCESS]
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2012

Originalarbeit (Zeitschrift)

** Eichmann, TO; Kumari, M; Haas, JT; Farese, RV; Zimmermann, R; Lass, A; Zechner, R Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.
J Biol Chem. 2012; 287(49): 41446-57. Doi: 10.1074/jbc.M112.400416 [OPEN ACCESS]
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Übersichtsarbeit

** Zechner, R; Zimmermann, R; Eichmann, TO; Kohlwein, SD; Haemmerle, G; Lass, A; Madeo, F FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.
Cell Metab. 2012; 15(3): 279-91. Doi: 10.1016/j.cmet.2011.12.018 [OPEN ACCESS]
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2011

Originalarbeit (Zeitschrift)

** Etschmaier, K; Becker, T; Eichmann, TO; Schweinzer, C; Scholler, M; Tam-Amersdorfer, C; Poeckl, M; Schuligoi, R; Kober, A; Chirackal, Manavalan, AP; Rechberger, GN; Streith, IE; Zechner, R; Zimmermann, R; Panzenboeck, U Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.
J Neurochem. 2011; 119(5):1016-28 Doi: 10.1111/j.1471-4159.2011.07498.x [OPEN ACCESS]
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** Haemmerle, G; Moustafa, T; Woelkart, G; Büttner, S; Schmidt, A; van, de, Weijer, T; Hesselink, M; Jaeger, D; Kienesberger, PC; Zierler, K; Schreiber, R; Eichmann, T; Kolb, D; Kotzbeck, P; Schweiger, M; Kumari, M; Eder, S; Schoiswohl, G; Wongsiriroj, N; Pollak, NM; Radner, FP; Preiss-Landl, K; Kolbe, T; Rülicke, T; Pieske, B; Trauner, M; Lass, A; Zimmermann, R; Hoefler, G; Cinti, S; Kershaw, EE; Schrauwen, P; Madeo, F; Mayer, B; Zechner, R ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Nat Med. 2011; 17(9):1076-85 Doi: 10.1038/nm.2439 [OPEN ACCESS]
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2010

Originalarbeit (Zeitschrift)

** Radner, FP; Streith, IE; Schoiswohl, G; Schweiger, M; Kumari, M; Eichmann, TO; Rechberger, G; Koefeler, HC; Eder, S; Schauer, S; Theussl, HC; Preiss-Landl, K; Lass, A; Zimmermann, R; Hoefler, G; Zechner, R; Haemmerle, G Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
J Biol Chem. 2010; 285(10):7300-11 Doi: 10.1074/jbc.M109.081877 [OPEN ACCESS]
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** Schoiswohl, G; Schweiger, M; Schreiber, R; Gorkiewicz, G; Preiss-Landl, K; Taschler, U; Zierler, KA; Radner, FP; Eichmann, TO; Kienesberger, PC; Eder, S; Lass, A; Haemmerle, G; Alsted, TJ; Kiens, B; Hoefler, G; Zechner, R; Zimmermann, R Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids.
J Lipid Res. 2010; 51(3): 490-9. Doi: 10.1194/jlr.M001073 [OPEN ACCESS]
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2009

Übersichtsarbeit

** Schweiger, M; Lass, A; Zimmermann, R; Eichmann, TO; Zechner, R Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.
Am J Physiol Endocrinol Metab. 2009; 297(2): E289-96. Doi: 10.1152/ajpendo.00099.2009
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