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Department of Internal Medicine

Research Projects

Total: 3099 project(s)
of which:
- Current: 888 project(s)
- Completed: 2173 project(s)
- Publicly accessible: 574 project(s)
- Funded projects: 623 project(s)
- scient. event(s): 5 project(s)
- 3036 project(s) as leading unit and 63 project(s) as Med Uni Graz-partner unit

Project management at chosen institution:

Novel biomarkers for preeclampsia

Project type: EN: Forschungsförderung.
Project Leader: Trummer Olivia
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: Kulturamt der Stadt Graz, Stigergasse 2, 8020 Graz, Austria
Duration: 03.03.2025-31.12.2026
.

A novel cytokine based therapeutic strategy for treating acute myeloid leukemia

Project type: EN: Forschungsförderung.
Project Leader: Dutta Sayantanee
MUG Research Units: Division of Oncology ;
Funded by: Österreichische Krebshilfe Steiermark, Rudolf-Hans-Bartsch-Straße 15-17, 8042 Graz, Austria
Duration: 01.04.2025-31.03.2027
.

A prospective study to test a novel method for detection of minimal residual disease in acute myeloid leukemia

Project type: EN: Forschungsförderung.
Project Leader: Wölfler Albert
MUG Research Units: Division of Haematology ;
Funded by: Leukämiehilfe Steiermark, Kainbach bei Graz, Austria
Duration: 01.03.2018-31.12.2025
.

A Trial To evaluate the Efficacy of continuous glucose monitoring as add oN Therapy In peOple with Newly diagnosed Type 2 Diabetes

Project type: EN: Forschungsförderung.
Project Leader: Sourij Harald
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.02.2026-30.01.2030
.

Aberrant immune signaling and clonal dominance in splicing factor mutant myeloid malignancies

Project type: EN: Forschungsförderung.
Project Leader: Reinisch Andreas
MUG Research Units: Division of Haematology ;
Funded by: MEFOgraz , Neue Stiftingtalstraße 6 WEST, 8010 Graz, Austria
Duration: 01.04.2024-31.03.2026
.

Aberrant innate immune signaling in spliceosome-mutant myeloid neoplasms

Project type: EN: Forschungsförderung.
Project Leader: Reinisch Andreas
MUG Research Units: Division of Haematology ;
Funded by: Gilead Sciences, 2 Roundwood Avenue , South Building, Stockley Park, Uxbridge, UB11 1AF Middlesex, United Kingdom
Duration: 01.02.2024-31.01.2026
.

ACUTE EFFECTS AND TOLERABLITY OF EXERCISE IN LUNG CANCER PATIENTS UPON IMMUNOTHERAPY

Project type: EN: Forschungsförderung.
Project Leader: Taucher Elisabeth
MUG Research Units: Division of Respiratory Medicine ;
Funded by: Kulturamt der Stadt Graz, Stigergasse 2, 8020 Graz, Austria
Duration: 01.02.2025-01.02.2026
.

AGRA as novel biomarker for the prediction of severe infections in liver transplanted patients

Project type: EN: Forschungsförderung.
Project Leader: Horvath Angela
MUG Research Units: Division of Gastroenterology and Hepatology ;
Funded by: Österreichische Gesellschaft für Gastroenterologie und Hepatologie, Wien, Austria
Duration: 01.07.2019-31.12.2025
.

An open-label extension multi-centre trial in adult subjects diagnosed with Type 1 diabetes mellitus exploring the effect of long-term Verapamil SR therapy on the preservation of beta cell function.

Project type: EN: Forschungsförderung.
Project Leader: Pieber Thomas
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: JDRF - Juvenile Diabetes Research Foundation, 200 Vesey Street, New York, United States (USA)
Duration: 01.01.2025-31.12.2027
.

Analysis of the RAS/MAPK-ERK signal transduction cascade in acute myeloid leukemia

Project type: EN: Forschungsförderung.
Project Leader: Zebisch Armin
MUG Research Units: Division of Haematology ;
Funded by: Leukämiehilfe Steiermark, Kainbach bei Graz, Austria
Duration: 01.04.2017-30.06.2028
.

Antigen Presentation and Immunopathology in Heart Failure.

Project type: EN: Forschungsförderung.
Project Leader: Sattler Susanne
MUG Research Units: Division of Cardiology ; Otto Loewi Research Center (for Vascular Biology, Immunology and Inflammation) ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.10.2023-30.09.2027
.

Antihypertensive mechanisms of spermidine

Project type: EN: Forschungsförderung.
Project Leader: Abdellatif Mahmoud
MUG Research Units: Division of Cardiology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.10.2022-28.02.2026
.

Austrian Digital Atrial Fibrillation Screening and Intervention Program

Project type: EN: Forschungsförderung.
Project Leader: Manninger-Wünscher Martin
MUG Research Units: Division of Cardiology ;
Funded by: Ludwig Boltzmann Gesellschaft, Nußdorfer Straße 64, 1090 Wien, Austria
Duration: 01.10.2023-30.09.2027
.

Boosting immunotherapy in non-small cell lung cancer

Project type: EN: Forschungsförderung.
Project Leader: Jäger Vanessa
MUG Research Units: Division of Oncology ;
Funded by: Österreichische Gesellschaft für Hämatologie und Medizinische Onkologie, AKH-Wien, Klinik für Innere Medizin I Währinger Gürtel 18-20, 1090 Wien, Austria
Duration: 01.08.2024-31.12.2026
.

CBmed: MODUL - Microplastic Particles: A Hazard for Human Health Project 3 INTERACTION – HUMAN HEALTH EFFECTS – TREATMENT

Project type: EN: Forschungsförderung.
Project Leader: Stadlbauer-Köllner Vanessa
MUG Research Units: Division of Gastroenterology and Hepatology ;
Funded by: Österreichische Forschungsförderungsgesellschaft mbH (FFG/mit peer review), Sensengasse 1, 1090 Wien, Austria
Duration: 01.01.2022-31.12.2026
.

Characterizing Fecal Microbiota Treatment in Human Obesity

Project type: EN: Forschungsförderung.
Project Leader: Mader Julia
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.07.2021-30.06.2026
.

Characterizing the epigenetics of lung cancer progression to inform personalized treatment

Project type: EN: Forschungsförderung.
Project Leader: Vosberg Sebastian
MUG Research Units: Division of Oncology ;
Funded by: MEFOgraz , Neue Stiftingtalstraße 6 WEST, 8010 Graz, Austria
Duration: 01.02.2022-31.12.2026
.

Communicating stress to cell nuclei in cardiomyocytes

Project type: EN: Forschungsförderung.
Project Leader: Holzer Senka
MUG Research Units: Division of Cardiology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.03.2025-28.02.2029
.

CRISPR/Cas9-Based Genome Engineering to mimic Clonal Hematopoiesis and Myeloid Neoplasia in Human Hematopoietic Stem and Progenitor Cells

Project type: EN: Forschungsförderung.
Project Leader: Reinisch Andreas
MUG Research Units: Division of Haematology ;
Funded by: MEFOgraz , Neue Stiftingtalstraße 6 WEST, 8010 Graz, Austria
Duration: 01.02.2018-31.12.2025
.

Deciphering molecular pathways of sarcopenia in chronic kidney disease

Project type: EN: Forschungsförderung.
Project Leader: Schuller Max
MUG Research Units: Division of Nephrology ;
Funded by: Medizinische Universität Graz, Stiftingtalstraße 6, 8010 Graz, Austria
Duration: 01.02.2025-31.01.2027
.

Deciphering the impact of NR4A1 on the Tumor Microenvironment and Interaction of Immune and Lymphoma Cells in aggressive Lymphoma

Project type: EN: Forschungsförderung.
Project Leader: Zanker Matthias
MUG Research Units: Division of Haematology ;
Funded by: Stadt Graz, Graz, Austria
Duration: 01.06.2024-31.05.2027
.

Deciphering the role of necroptosis-induced inflammation in lung adenocarcinomas

Project type: EN: Forschungsförderung.
Project Leader: Jost Philipp
MUG Research Units: Division of Oncology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.01.2024-22.12.2027
.

Defining the role of the type I interferon pathway in the pathogenesis of giant cell arteritis

Project type: EN: Forschungsförderung.
Project Leader: Reisch Myriam Katja
MUG Research Units: Division of Rheumatology and Immunology ;
Funded by: Österreichische Gesellschaft für Rheumatologie, Dr. Boehringer-Gasse 5-11, 1121 Wien, Austria
Duration: 01.01.2024-31.12.2026
.

Dermal open flow microperfusion to determine changes in the skin microenvironment in vivo during SSc

Project type: EN: Forschungsförderung.
Project Leader: Keppler Selina Jessica
MUG Research Units: Division of Rheumatology and Immunology ;
Funded by: Verein zur Förderung der klinischen Abteilung für Rheumatologie, Auenbruggerplatz 15, 8036 Graz, Austria
Duration: 01.11.2024-31.12.2026
.

Developing a Leukemia Patient-Derived Xenotransplantation Repository for Predicting AML Treatment Response and Relapse

Project type: EN: Forschungsförderung.
Project Leader: Reinisch Andreas
MUG Research Units: Division of Haematology ;
Funded by: Leukämiehilfe Steiermark, Kainbach bei Graz, Austria
Duration: 01.03.2025-28.02.2027
.

Diet and Nutrition among patients with inflammatory bowel disease in Austria and Germany

Project type: EN: Forschungsförderung.
Project Leader: Hoegenauer Christoph
MUG Research Units: Division of Gastroenterology and Hepatology ;
Funded by: Österreichische Gesellschaft für Gastroenterologie und Hepatologie, Wien, Austria
Duration: 01.03.2024-31.12.2025
.

Digitaler Diabetes Assistant

Project type: EN: Forschungsförderung.
Project Leader: Lichtenegger Katharina
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: Europäische Kommission, Rue de la Loi, Brussels, Belgium
Duration: 01.10.2023-31.12.2025
.

Digitalisation of Innovative Care Processes to Unburden and Empower Nurses

Project type: EN: Forschungsförderung.
Project Leader: Lichtenegger Katharina
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: Österreichische Forschungsförderungsgesellschaft mbH (FFG/mit peer review), Sensengasse 1, 1090 Wien, Austria
Duration: 01.03.2024-29.02.2028
.

Efficacy of an Assisted therapy optimizing Module to impove Physician adherence with guideline-directed medical therapy in patients with heart failure - "AMPEL" trial

Project type: EN: Forschungsförderung.
Project Leader: Wallner Markus
MUG Research Units: Division of Cardiology ;
Funded by: Gesundheitsfonds Steiermark, Herrengasse 28, 8010 Graz, Austria
Duration: 01.04.2025-31.03.2027
.

Energetics-transcription coupling in hypertensive heart

Project type: EN: Forschungsförderung.
Project Leader: Holzer Senka
MUG Research Units: Division of Cardiology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.01.2025-31.12.2029
.

Energizing the failing heart

Project type: EN: Forschungsförderung.
Project Leader: Abdellatif Mahmoud
MUG Research Units: Division of Cardiology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.05.2024-30.04.2027
.

Enhancing Cognitive Longevity through Lifestyle and Nutrition

Project type: EN: Forschungsförderung.
Project Leader: Sourij Harald
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 03.02.2025-31.01.2028
.

Establishing an efficient and simple method to improve diagnostic procedures and performance in primary hyperparathyroidism

Project type: EN: Forschungsförderung.
Project Leader: Trummer Christian
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: Österreichische Institution für Endokrinologie und Stoffwechsel, Rennweg 3, 6020 Innsbruck, Austria
Duration: 01.08.2020-31.07.2026
.

Evaluation of tumor progression in metastasised in neuroendocrine neoplasia (NEN) with biochemical and imaging techniques

Project type: EN: Forschungsförderung.
Project Leader: Constantini-Kump Patrizia
MUG Research Units: Division of Gastroenterology and Hepatology ;
Funded by: MEFOgraz , Neue Stiftingtalstraße 6 WEST, 8010 Graz, Austria
Duration: 01.01.2017-31.12.2025
.

Exercise as a tool to improve the response to immunotherapy in lung cancer.

Project type: EN: Forschungsförderung.
Project Leader: Taucher Elisabeth
MUG Research Units: Division of Respiratory Medicine ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.03.2025-28.02.2028
.

Exploring the Glycome: Identifying Glycosylation-Related Biomarkers for severity stratification in Chronic Fatigue Syndrome

Project type: EN: Forschungsförderung.
Project Leader: Keppler Selina Jessica
MUG Research Units: Division of Rheumatology and Immunology ;
Funded by: Wiener Wirtschafts-, Forschungs und Technologiefonds, Schlickgasse 3/12, 1090 Wien, Austria
Duration: 01.01.2025-28.02.2026
.

Expression manipulation of osteoporosis-associated microRNAs in human MSC-derived osteoblasts

Project type: EN: Forschungsförderung.
Project Leader: Trummer Olivia
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: MEFOgraz , Neue Stiftingtalstraße 6 WEST, 8010 Graz, Austria
Duration: 01.05.2019-31.03.2026
.

FXR liver adipose axis

Project type: EN: Forschungsförderung.
Project Leader: Wagner Martin
MUG Research Units: Division of Gastroenterology and Hepatology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.11.2023-31.10.2027
.

Galectin-3 targeted antifungal prophylaxis in ICU influenza

Project type: EN: Forschungsförderung.
Project Leader: Hönigl Martin
MUG Research Units: Division of Infectious Diseases ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 01.04.2025-31.03.2028
.

Guiding Methimazole Therapy in Graves’ Disease - a Randomized Controlled Trial Comparing a Computer-Aided Treatment (Digital Thyroid - DigiThy) versus Usual Care

Project type: EN: Forschungsförderung.
Project Leader: Theiler-Schwetz Verena
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: Kulturamt der Stadt Graz, Stigergasse 2, 8020 Graz, Austria
Duration: 01.09.2024-01.09.2027
.

Gut fungal translocation measured by 1,3-Beta-D-Glucan and its role in patients with liver cirrhosis

Project type: EN: Forschungsförderung.
Project Leader: Egger Matthias Florian
MUG Research Units: Division of Infectious Diseases ;
Funded by: Österreichische Gesellschaft für Gastroenterologie und Hepatologie, Wien, Austria
Duration: 01.08.2024-31.12.2025
.

Hypermethylation as a mechanism for cisplatin resistance in germ cell tumors

Project type: EN: Forschungsförderung.
Project Leader: Terbuch Angelika
MUG Research Units: Division of Oncology ;
Funded by: Österreichische Gesellschaft für Hämatologie und Medizinische Onkologie, AKH-Wien, Klinik für Innere Medizin I Währinger Gürtel 18-20, 1090 Wien, Austria
Duration: 01.01.2023-31.12.2025
.

Identifying novel lung cancer drivers: Unravelling the functional role of genes affected by large copy number gains

Project type: EN: Forschungsförderung.
Project Leader: Dengler Michael
MUG Research Units: Division of Oncology ;
Funded by: Verein für Krebskranke an der Medizinischen Universität Graz, Auenbruggerplatz 15, 8036 Graz, Austria
Duration: 01.10.2024-31.12.2026
.

Identifying novel targets to combat aberrant TP53 mediated therapeutic resistance in acute myeloid leukemia using CRISPRko screens

Project type: EN: Forschungsförderung.
Project Leader: Dutta Sayantanee
MUG Research Units: Division of Oncology ;
Funded by: Gilead Sciences, 2 Roundwood Avenue , South Building, Stockley Park, Uxbridge, UB11 1AF Middlesex, United Kingdom
Duration: 01.02.2024-31.07.2026
.

Immune cell composition and function in patients with and without steroid-refractory acute and chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation

Project type: EN: Forschungsförderung.
Project Leader: Gaksch Lukas
MUG Research Units: Division of Haematology ;
Funded by: Medizinische Universität Graz, Stiftingtalstraße 6, 8010 Graz, Austria MEFOgraz , Neue Stiftingtalstraße 6 WEST, 8010 Graz, Austria
Duration: 01.01.2024-31.12.2025
.

Immune cell composition and function in patients with and without steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic cell transplantation

Project type: EN: Forschungsförderung.
Project Leader: Gaksch Lukas
MUG Research Units: Division of Haematology ;
Funded by: Kulturamt der Stadt Graz, Stigergasse 2, 8020 Graz, Austria
Duration: 01.05.2023-30.04.2026
.

Impact of pulmonary exercise hemodynamics on right ventricular function

Project type: EN: Forschungsförderung.
Project Leader: Douschan Philipp
MUG Research Units: Division of Respiratory Medicine ;
Funded by: Österreichische Gesellschaft für Pneumologie, Operngasse 20B, 1040 Wien, Austria
Duration: 01.12.2023-30.06.2026
.

In silico characterization of 1q21 amplification in advanced lung adenocarcinoma

Project type: EN: Forschungsförderung.
Project Leader: Vizar Cisarova Katarina
MUG Research Units: Division of Oncology ;
Funded by: MEFOgraz , Neue Stiftingtalstraße 6 WEST, 8010 Graz, Austria
Duration: 01.02.2025-31.01.2026
.

In vivo competition of AML cells harboring different TP53 aberrations

Project type: EN: Forschungsförderung.
Project Leader: Dutta Sayantanee
MUG Research Units: Division of Oncology ;
Funded by: Leukämiehilfe Steiermark, Kainbach bei Graz, Austria
Duration: 01.06.2025-01.06.2026
.

Innovative approaches to strengthen immunotherapy in lung cancer

Project type: EN: Forschungsförderung.
Project Leader: Jäger Vanessa
MUG Research Units: Division of Oncology ;
Funded by: Österreichische Krebshilfe Steiermark, Rudolf-Hans-Bartsch-Straße 15-17, 8042 Graz, Austria
Duration: 01.04.2025-31.03.2027
.

Integrating exercise and NAD+ to reduce cardiometabolic risk

Project type: EN: Forschungsförderung.
Project Leader: Sedej Simon
MUG Research Units: Division of Cardiology ;
Funded by: BioTechMed-Graz, Mozartgasse 12/II, 8010 Graz, Austria
Duration: 01.03.2023-28.02.2026
.

Integration of Early Palliative Care into Oncology

Project type: EN: Forschungsförderung.
Project Leader: Huemer Matthias
MUG Research Units: Division of Oncology ;
Funded by: Österreichische Gesellschaft für Hämatologie und Medizinische Onkologie, AKH-Wien, Klinik für Innere Medizin I Währinger Gürtel 18-20, 1090 Wien, Austria
Duration: 01.07.2021-31.12.2025
.

INTERACT-EUROPE 100

Project type: EN: Forschungsförderung.
Project Leader: Jost Philipp
MUG Research Units: Division of Oncology ;
Funded by: Europäische Kommission, Rue de la Loi, Brussels, Belgium
Duration: 01.12.2023-30.11.2026
.

Intermittent Fasting and Exercise in Type 2 Diabetes

Project type: EN: Forschungsförderung.
Project Leader: Sourij Harald
MUG Research Units: Division of Endocrinology and Diabetology ;
Funded by: FWF, Fonds zur Förderung der Wissenschaftlichen Forschung, Georg-Coch-Platz 2, 1010 Wien, Austria
Duration: 15.06.2024-14.06.2028
.

Investigating the pro-fibrotic potential of B cells in the skin niche during Systemic Sclerosis

Project type: EN: Forschungsförderung.
Project Leader: Keppler Selina Jessica
MUG Research Units: Division of Rheumatology and Immunology ;
Funded by: Edith Busch Stiftung , 72290 Lossburg, Austria
Duration: 01.08.2024-31.07.2026
.

Investigating the properties of NR4As in shaping the tumour microenvironment in diffuse large B cell lymphomas

Project type: EN: Forschungsförderung.
Project Leader: Deutsch Alexander
MUG Research Units: Division of Haematology ;
Funded by: Österreichische Gesellschaft für Hämatologie und Medizinische Onkologie, AKH-Wien, Klinik für Innere Medizin I Währinger Gürtel 18-20, 1090 Wien, Austria
Duration: 02.09.2024-01.09.2026
.