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Search Items: STATINS, . hits: 85

2023

Akhmetshina, A; Kratky, D; Rendina-Ruedy, E Influence of Cholesterol on the Regulation of Osteoblast Function
METABOLITES. 2023; 13(4): 578 Doi: 10.3390/metabo13040578
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2022

Minichsdorfer, C; Fuereder, T; Leutner, M; Singer, CF; Kacerovsky-Strobl, S; Egle, D; Greil, R; Balic, M; Fitzal, F; Pfeiler, G; Frantal, S; Bartsch, R; Gnant, M Effect of concomitant statin treatment in postmenopausal patients with hormone receptor-positive early-stage breast cancer receiving adjuvant denosumab or placebo: a post hoc analysis of ABCSG-18.
ESMO Open. 2022; 7(2):100426 Doi: 10.1016/j.esmoop.2022.100426 [OPEN ACCESS]
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Posch-Pertl, L; Michelitsch, M; Wagner, G; Wildner, B; Silbernagel, G; Pregartner, G; Wedrich, A Cholesterol and glaucoma: a systematic review and meta-analysis.
Acta Ophthalmol. 2022; 100(2):148-158 Doi: 10.1111/aos.14769 [OPEN ACCESS]
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Waldeck-Weiermair, M; Yadav, S; Kaynert, J; Thulabandu, VR; Pandey, AK; Spyropoulos, F; Covington, T; Das, AA; Kruger, C; Michel, T Differential endothelial hydrogen peroxide signaling via Nox isoforms: Critical roles for Rac1 and modulation by statins
REDOX BIOL. 2022; 58: 102539 Doi: 10.1016/j.redox.2022.102539 [OPEN ACCESS]
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2021

Dopheide, JF; Adam, L; Wiedmer, S; Kaspar, M; Silbernagel, G; Baumgartner, I; Drexel, H Improved Lipid Target Level Attainment in Patients with Peripheral Artery Disease.
Curr Vasc Pharmacol. 2021; 19(6): 634-642. Doi: 10.2174/1570161119666210111123621
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Fischer, LT; Hochfellner, DA; Knoll, L; Pöttler, T; Mader, JK; Aberer, F Real-world data on metabolic effects of PCSK9 inhibitors in a tertiary care center in patients with and without diabetes mellitus.
Cardiovasc Diabetol. 2021; 20(1): 89-89. Doi: 10.1186/s12933-021-01283-w [OPEN ACCESS]
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2020

Genser, B; Wanner, C; März, W A scoring system for predicting individual treatment effects of statins in type 2 diabetes patients on haemodialysis.
Eur J Prev Cardiol. 2020; 31(4):2047487320905721-2047487320905721 Doi: 10.1177/2047487320905721
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Härdtner, C; Kornemann, J; Krebs, K; Ehlert, CA; Jander, A; Zou, J; Starz, C; Rauterberg, S; Sharipova, D; Dufner, B; Hoppe, N; Dederichs, TS; Willecke, F; Stachon, P; Heidt, T; Wolf, D; von Zur Mühlen, C; Madl, J; Kohl, P; Kaeser, R; Boettler, T; Pieterman, EJ; Princen, HMG; Ho-Tin-Noé, B; Swirski, FK; Robbins, CS; Bode, C; Zirlik, A; Hilgendorf, I Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering.
Basic Res Cardiol. 2020; 115(6): 78-78. Doi: 10.1007/s00395-020-00838-4 [OPEN ACCESS]
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Heine, GH; Eller, K; Stadler, JT; Rogacev, KS; Marsche, G, ;RITERM, study, group;RITERM, study, group Lipid-modifying therapy in chronic kidney disease: Pathophysiological and clinical considerations.
Pharmacol Ther. 2020; 207:107459 Doi: 10.1016/j.pharmthera.2019.107459
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McGregor, GH; Campbell, AD; Fey, SK; Tumanov, S; Sumpton, D; Blanco, GR; Mackay, G; Nixon, C; Vazquez, A; Sansom, OJ; Kamphorst, JJ Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor Response.
Cancer Res. 2020; 80(2):175-188 Doi: 10.1158/0008-5472.CAN-19-0644
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2019

Jud, P; Sourij, H Therapeutic options to reduce advanced glycation end products in patients with diabetes mellitus: A review.
Diabetes Res Clin Pract. 2019; 148:54-63 Doi: 10.1016/j.diabres.2018.11.016
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Silbernagel, G; Steiner, LK; Hollstein, T; Fauler, G; Scharnagl, H; Stojakovic, T; Schumann, F; Bölükbasi, B; März, W; Steinhagen-Thiessen, E; Laufs, U; Kassner, U The interrelations between PCSK9 metabolism and cholesterol synthesis and absorption.
J Lipid Res. 2019; 60(1): 161-167. Doi: 10.1194/jlr.P088583 [OPEN ACCESS]
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Wadsack, D; Sattler, H; Kleber, ME; Eirich, K; Scharnagl, H; Fauler, G; März, W; Grammer, TB Recurrent tendosynovitis as a rare manifestation of a lipid disorder.
J Clin Lipidol. 2019; 13(1): 54-61. Doi: 10.1016/j.jacl.2018.10.005 (- Case Report)
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Wascher, TC; Paulweber, B; Toplak, H; Saely, CH; Drexel, H; Föger, B; Hoppichler, F; Stulnig, T; Stingl, H; Clodi, M; den Ausschuss Leitlinien [Lipids-Diagnosis and therapy in diabetes mellitus (Update 2019)].
Wien Klin Wochenschr. 2019; 131(Suppl 1):136-138 Doi: 10.1007/s00508-019-1444-2
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2018

Šabanović, Š; Ljiljana, MT; Babič, F; Vadovský, M; Paralič, J; Včev, A; Holzinger, A Metabolic syndrome in hypertensive women in the age of menopause: a case study on data from general practice electronic health records.
BMC MED INFORM DECIS. 2018; 18(1): 24-24. Doi: 10.1186/s12911-018-0601-2 [OPEN ACCESS]
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Bramlage, P; März, W; Westermann, D; Weisser, B; Wirtz, JH; Zeymer, U; Baumgart, P; van Mark, G; Laufs, U; Krämer, BK; Unger, T [Management of different cardiovascular risk factors with a combination tablet (polypill)].
HERZ. 2018; 43(3): 246-257. Doi: 10.1007/s00059-017-4554-5
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Ferrières, J; Lautsch, D; Gitt, AK; De Ferrari, G; Toplak, H; Elisaf, M; Drexel, H; Horack, M; Baxter, C; Ambegaonkar, B; Brudi, P; Toth, PP Body mass index impacts the choice of lipid-lowering treatment with no correlation to blood cholesterol - Findings from 52 916 patients in the Dyslipidemia International Study (DYSIS).
Diabetes Obes Metab. 2018; 20(11):2670-2674 Doi: 10.1111/dom.13415 [OPEN ACCESS]
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Mach, F; Ray, KK; Wiklund, O; Corsini, A; Catapano, AL; Bruckert, E; De Backer, G; Hegele, RA; Hovingh, GK; Jacobson, TA; Krauss, RM; Laufs, U; Leiter, LA; März, W; Nordestgaard, BG; Raal, FJ; Roden, M; Santos, RD; Stein, EA; Stroes, ES; Thompson, PD; Tokgözoglu, L; Vladutiu, GD; Gencer, B; Stock, JK; Ginsberg, HN; Chapman, MJ; European Atherosclerosis Society Consensus Panel Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract.
EUR HEART J. 2018; 39(27): 2526-2539. Doi: 10.1093/eurheartj/ehy182 [OPEN ACCESS]
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Panahi, M; Vadgama, N; Kuganesan, M; Ng, FS; Sattler, S Immunopharmacology of Post-Myocardial Infarction and Heart Failure Medications.
J Clin Med. 2018; 7(11): Doi: 10.3390/jcm7110403 [OPEN ACCESS]
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2017

Descamps, OS; Fraass, U; Dent, R; März, W; Gouni-Berthold, I Anti-PCSK9 antibodies for hypercholesterolaemia: Overview of clinical data and implications for primary care.
Int J Clin Pract. 2017; 71(8): Doi: 10.1111/ijcp.12979 [OPEN ACCESS]
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Silbernagel, G; Scharnagl, H; Kleber, ME; Stojakovic, T; März, W Circulating proprotein convertase subtilisin-kexin type 9, all-cause mortality, and cardiovascular mortality: The Ludwigshafen Risk and Cardiovascular Health study.
Eur J Prev Cardiol. 2017; 24(10):1095-1101 Doi: 10.1177/2047487317693938
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2016

Gouni-Berthold, I; Descamps, OS; Fraass, U; Hartfield, E; Allcott, K; Dent, R; März, W Systematic review of published Phase 3 data on anti-PCSK9 monoclonal antibodies in patients with hypercholesterolaemia.
Br J Clin Pharmacol. 2016; 82(6):1412-1443 Doi: 10.1111/bcp.13066 [OPEN ACCESS]
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Grammer, T; Kleber, M; Silbernagel, G; Scharnagl, H; März, W [Residual risk: The roles of triglycerides and high density lipoproteins].
Dtsch Med Wochenschr. 2016; 141(12):870-877 Doi: 10.1055/s-0042-104049
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März, W; Scharnagl, H; Gouni-Berthold, I; Silbernagel, G; Dressel, A; Grammer, TB; Landmesser, U; Dieplinger, H; Windler, E; Laufs, U LDL-Cholesterol: Standards of Treatment 2016: A German Perspective.
Am J Cardiovasc Drugs. 2016; 16(5):323-336 Doi: 10.1007/s40256-016-0179-y [OPEN ACCESS]
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Wascher, TC; Paulweber, B; Toplak, H; Säly, CH; Drexel, H; Föger, B; Hoppichler, F [Lipids--Diagnosis and therapy in diabetes mellitus].
Wien Klin Wochenschr. 2016; 128 Suppl 2(4):S68-S70 Doi: 10.1007/s00508-015-0933-1 [OPEN ACCESS]
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2015

Hackl, G; Belaj, K; Gary, T; Rief, P; Deutschmann, H; Seinost, G; Brodmann, M; Hafner, F COPART Risk Score Predicts Long-term Mortality in Peripheral Arterial Occlusive Disease.
Eur J Vasc Endovasc Surg. 2015; 50(1):94-100 Doi: 10.1016/j.ejvs.2015.04.009 [OPEN ACCESS]
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Laufs, U; Scharnagl, H; Halle, M; Windler, E; Endres, M; März, W Treatment Options for Statin-Associated Muscle Symptoms.
Dtsch Arztebl Int. 2015; 112(44):748-755 Doi: 10.3238/arztebl.2015.0748 [OPEN ACCESS]
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Laufs, U; Scharnagl, H; März, W Statin intolerance.
Curr Opin Lipidol. 2015; 26(6): 492-501. Doi: 10.1097/MOL.0000000000000236
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Mirjanic-Azaric, B; Rizzo, M; Jürgens, G; Hallstroem, S; Srdic, S; Marc, J; Cerne, D Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients.
Scand J Clin Lab Invest. 2015; 75(5):382-389 Doi: 10.3109/00365513.2015.1031691
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2014

Drolz, A; Horvatits, T; Michl, B; Roedl, K; Schellongowski, P; Holzinger, U; Zauner, C; Heinz, G; Madl, C; Trauner, M; Fuhrmann, V Statin therapy is associated with reduced incidence of hypoxic hepatitis in critically ill patients.
J Hepatol. 2014; 60(6):1187-1193 Doi: 10.1016/j.jhep.2014.01.019
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Gylling, H; Plat, J; Turley, S; Ginsberg, HN; Ellegard, L; Jessup, W; Jones, PJ; Lutjohann, D; Maerz, W; Masana, L; Silbernagel, G; Staels, B; Boren, J; Catapano, AL; De Backer, G; Deanfield, J; Descamps, OS; Kovanen, PT; Riccardi, G; Tokgozoglu, L; Chapman, MJ Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease
ATHEROSCLEROSIS. 2014; 232(2): 346-360. Doi: 10.1016/j.atherosclerosis.2013.11.043 [OPEN ACCESS]
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Klose, G; Beil, FU; Dieplinger, H; von Eckardstein, A; Föger, B; Gouni-Berthold, I; Heigl, F; Koenig, W; Kostner, GM; Landmesser, U; Laufs, U; Leistikow, F; März, W; Noll, G; Parhofer, KG; Paulweber, B; Riesen, WF; Schaefer, JR; Steinhagen-Thiessen, E; Steinmetz, A; Toplak, H; Wanner, C; Windler, E; American Heart Association, American College of Cardiology New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk.
Wien Klin Wochenschr. 2014; 126(5-6):169-175 Doi: 10.1007/s00508-014-0513-9
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Klose, G; Beil, FU; Dieplinger, H; von Eckardstein, A; Föger, B; Gouni-Berthold, I; Koenig, W; Kostner, GM; Landmesser, U; Laufs, U; Leistikow, F; März, W; Merkel, M; Müller-Wieland, D; Noll, G; Parhofer, KG; Paulweber, B; Riesen, W; Schaefer, JR; Steinhagen-Thiessen, E; Steinmetz, A; Toplak, H; Wanner, C; Windler, E [New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk : Statement of the D•A•CH Society for Prevention of Cardiovascular Diseases, the Austrian Atherosclerosis Society and the Working Group on Lipids and Atherosclerosis (AGLA) of the Swiss Society for Cardiology].
Internist (Berl). 2014; 55(5):601-606 Doi: 10.1007/s00108-014-3492-z [OPEN ACCESS]
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Klose, G; Laufs, U; März, W; Windler, E Familial hypercholesterolemia: developments in diagnosis and treatment.
Dtsch Arztebl Int. 2014; 111(31-32):523-529 Doi: 10.3238/arztebl.2014.0523 [OPEN ACCESS]
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Lötsch, F; Königsbrügge, O; Posch, F; Zielinski, C; Pabinger, I; Ay, C Statins are associated with low risk of venous thromboembolism in patients with cancer: a prospective and observational cohort study.
Thromb Res. 2014; 134(5): 1008-1013. Doi: 10.1016/j.thromres.2014.09.001
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Silbernagel, G; Baumgartner, I; Wanner, C; März, W Toward individualized cholesterol-lowering treatment in end-stage renal disease.
J Ren Nutr. 2014; 24(2):65-71 Doi: 10.1053/j.jrn.2013.11.001 [OPEN ACCESS]
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Xiong, Y; Wong, A; Cavalieri, M; Schmidt, R; Chu, WW; Liu, X; Wong, KS; Mok, V Prestroke statins, progression of white matter hyperintensities, and cognitive decline in stroke patients with confluent white matter hyperintensities.
Neurotherapeutics. 2014; 11(3):606-611 Doi: 10.1007/s13311-014-0270-5 [OPEN ACCESS]
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2013

Rieken, M; Kluth, LA; Xylinas, E; Seitz, C; Fajkovic, H; Karakiewicz, PI; Lotan, Y; Briganti, A; Loidl, W; Faison, T; Crivelli, JJ; Scherr, DS; Bachmann, A; Tewari, AK; Kautzky-Willer, A; Pummer, K; Shariat, SF Impact of statin use on biochemical recurrence in patients treated with radical prostatectomy.
Prostate Cancer Prostatic Dis. 2013; 16(4):367-371 Doi: 10.1038/pcan.2013.31 [OPEN ACCESS]
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2012

Wascher, TC; Paulweber, B; Toplak, H; Saely, C; Drexel, H Lipids: diagnosis and therapy in type 2 diabetes].
Wien Klin Wochenschr. 2012; 124 Suppl 2(12):28-30 Doi: 10.1007/s00508-012-0273-3
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2011

März, W; Genser, B; Drechsler, C; Krane, V; Grammer, TB; Ritz, E; Stojakovic, T; Scharnagl, H; Winkler, K; Holme, I; Holdaas, H; Wanner, C; German Diabetes and Dialysis Study Investigators Atorvastatin and low-density lipoprotein cholesterol in type 2 diabetes mellitus patients on hemodialysis.
Clin J Am Soc Nephrol. 2011; 6(6):1316-1325 Doi: 10.2215/CJN.09121010 [OPEN ACCESS]
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Schweinzer, C; Kober, A; Lang, I; Etschmaier, K; Scholler, M; Kresse, A; Sattler, W; Panzenboeck, U Processing of endogenous AβPP in blood-brain barrier endothelial cells is modulated by liver-X receptor agonists and altered cellular cholesterol homeostasis.
J Alzheimers Dis. 2011; 27(2):341-360 Doi: 10.3233/JAD-2011-110854
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2010

Eller, P; Eller, K; Wolf, AM; Reinstadler, SJ; Tagwerker, A; Patsch, JR; Mayer, G; Rosenkranz, AR Atorvastatin attenuates murine anti-glomerular basement membrane glomerulonephritis.
Kidney Int. 2010; 77(5):428-435 Doi: 10.1038/ki.2009.478 [OPEN ACCESS]
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Helbing, T; Rothweiler, R; Heinke, J; Goetz, L; Diehl, P; Zirlik, A; Patterson, C; Bode, C; Moser, M BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1.
ARTERIOSCL THROM VAS. 2010; 30(3): 554-560. Doi: 10.1161/ATVBAHA.109.201087 [OPEN ACCESS]
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Mullen, PJ; Lüscher, B; Scharnagl, H; Krähenbühl, S; Brecht, K Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy.
Biochem Pharmacol. 2010; 79(8): 1200-1209. Doi: 10.1016/j.bcp.2009.12.007
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Silbernagel, G; Fauler, G; Hoffmann, MM; Lütjohann, D; Winkelmann, BR; Boehm, BO; März, W The associations of cholesterol metabolism and plasma plant sterols with all-cause and cardiovascular mortality.
J Lipid Res. 2010; 51(8):2384-2393 Doi: 10.1194/jlr.P002899 [OPEN ACCESS]
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Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; März, W; Wascher, TC; Trauner, M Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment.
Atherosclerosis. 2010; 209(1): 178-183. Doi: 10.1016/j.atherosclerosis.2009.08.052
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Zollner, G; Wagner, M; Trauner, M Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity.
Pharmacol Ther. 2010; 126(3):228-243 Doi: 10.1016/j.pharmthera.2010.03.005
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2009

Tancevski, I; Eller, P; Patsch, JR; Ritsch, A The resurgence of thyromimetics as lipid-modifying agents.
Curr Opin Investig Drugs. 2009; 10(9):912-918 [OPEN ACCESS]
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Werdan, K; Schmidt, H; Ebelt, H; Zorn-Pauly, K; Koidl, B; Hoke, RS; Heinroth, K; Müller-Werdan, U Impaired regulation of cardiac function in sepsis, SIRS, and MODS.
Can J Physiol Pharmacol. 2009; 87(4):266-274 Doi: 10.1139/Y09-012 [Poster]
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Zollner, G; Trauner, M Nuclear receptors as therapeutic targets in cholestatic liver diseases.
Br J Pharmacol. 2009; 156(1):7-27 Doi: 10.1111/j.1476-5381.2008.00030.x [OPEN ACCESS]
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