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Search Items: RAPAMYCIN, . hits: 39

2018

Barzaghi, F; Amaya Hernandez, LC; Neven, B; Ricci, S; Kucuk, ZY; Bleesing, JJ; Nademi, Z; Slatter, MA; Ulloa, ER; Shcherbina, A; Roppelt, A; Worth, A; Silva, J; Aiuti, A; Murguia-Favela, L; Speckmann, C; Carneiro-Sampaio, M; Fernandes, JF; Baris, S; Ozen, A; Karakoc-Aydiner, E; Kiykim, A; Schulz, A; Steinmann, S; Notarangelo, LD; Gambineri, E; Lionetti, P; Shearer, WT; Forbes, LR; Martinez, C; Moshous, D; Blanche, S; Fisher, A; Ruemmele, FM; Tissandier, C; Ouachee-Chardin, M; Rieux-Laucat, F; Cavazzana, M; Qasim, W; Lucarelli, B; Albert, MH; Kobayashi, I; Alonso, L; Diaz De Heredia, C; Kanegane, H; Lawitschka, A; Seo, JJ; Gonzalez-Vicent, M; Diaz, MA; Goyal, RK; Sauer, MG; Yesilipek, A; Kim, M; Yilmaz-Demirdag, Y; Bhatia, M; Khlevner, J; Richmond Padilla, EJ; Martino, S; Montin, D; Neth, O; Molinos-Quintana, A; Valverde-Fernandez, J; Broides, A; Pinsk, V; Ballauf, A; Haerynck, F; Bordon, V; Dhooge, C; Garcia-Lloret, ML; Bredius, RG; Kałwak, K; Haddad, E; Seidel, MG; Duckers, G; Pai, SY; Dvorak, CC; Ehl, S; Locatelli, F; Goldman, F; Gennery, AR; Cowan, MJ; Roncarolo, MG; Bacchetta, R; Primary Immune Deficiency Treatment Consortium (PIDTC) and the Inborn Errors Working Party (IEWP) of the European Society for Blood and Marrow Transplantation (EBMT) Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study.
J Allergy Clin Immunol. 2018; 141(3):1036-1049 [OPEN ACCESS]
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Frauscher, B; Kirsch, AH; Schabhuttl, C; Schweighofer, K; Ketszeri, M; Pollheimer, M; Dragun, D; Schroder, K; Rosenkranz, AR; Eller, K; Eller, P Autophagy Protects From Uremic Vascular Media Calcification
FRONT IMMUNOL. 2018; 9: 1866
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Leskoske, KL; Roelants, FM; Emmerstorfer-Augustin, A; Augustin, CM; Si, EP; Hill, JM; Thorner, J Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2.
Genes Dev. 2018; 32(23-24):1576-1590 [OPEN ACCESS]
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2017

Bürger, C; Shirsath, N; Lang, V; Diehl, S; Kaufmann, R; Weigert, A; Han, YY; Ringel, C; Wolf, P Blocking mTOR Signalling with Rapamycin Ameliorates Imiquimod-induced Psoriasis in Mice.
Acta Derm Venereol. 2017; 97(9):1087-1094 [OPEN ACCESS]
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Golob-Schwarzl, N; Krassnig, S; Toeglhofer, AM; Park, YN; Gogg-Kamerer, M; Vierlinger, K; Schröder, F; Rhee, H; Schicho, R; Fickert, P; Haybaeck, J New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.
Eur J Cancer. 2017; 83(60):56-70
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Golob-Schwarzl, N; Schweiger, C; Koller, C; Krassnig, S; Gogg-Kamerer, M; Gantenbein, N; Toeglhofer, AM; Wodlej, C; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Regenbrecht, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Oncotarget. 2017; 8(60):101224-101243 [OPEN ACCESS]
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Riedl, A; Schlederer, M; Pudelko, K; Stadler, M; Walter, S; Unterleuthner, D; Unger, C; Kramer, N; Hengstschläger, M; Kenner, L; Pfeiffer, D; Krupitza, G; Dolznig, H Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses.
J Cell Sci. 2017; 130(1):203-218 [OPEN ACCESS]
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2016

Baranyi, A; Amouzadeh-Ghadikolai, O; von Lewinski, D; Rothenhäusler, HB; Theokas, S; Robier, C; Mangge, H; Reicht, G; Hlade, P; Meinitzer, A Branched-Chain Amino Acids as New Biomarkers of Major Depression - A Novel Neurobiology of Mood Disorder.
PLoS One. 2016; 11(8):e0160542-e0160542 [OPEN ACCESS]
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Fröhlich, LF; Mrakovcic, M; Smole, C; Zatloukal, K Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway.
Cancer Cell Int. 2016; 16(1):68-68 [OPEN ACCESS]
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Jahn, SW; Kashofer, K; Thüringer, A; Abete, L; Winter, E; Eidenhammer, S; Viertler, C; Tavassoli, F; Moinfar, F Mutation Profiling of Usual Ductal Hyperplasia of the Breast Reveals Activating Mutations Predominantly at Different Levels of the PI3K/AKT/mTOR Pathway.
Am J Pathol. 2016; 186(1):15-23 [OPEN ACCESS]
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Verbrugge, SE; Al, M; Assaraf, YG; Kammerer, S; Chandrupatla, DM; Honeywell, R; Musters, RP; Giovannetti, E; O'Toole, T; Scheffer, GL; Krige, D; de Gruijl, TD; Niessen, HW; Lems, WF; Kramer, PA; Scheper, RJ; Cloos, J; Ossenkoppele, GJ; Peters, GJ; Jansen, G Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.
Oncotarget. 2016; 7(5):5240-5257 [OPEN ACCESS]
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2015

González, A; Shimobayashi, M; Eisenberg, T; Merle, DA; Pendl, T; Hall, MN; Moustafa, T TORC1 promotes phosphorylation of ribosomal protein S6 via the AGC kinase Ypk3 in Saccharomyces cerevisiae.
PLoS One. 2015; 10(3):e0120250-e0120250 [OPEN ACCESS]
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Lackner, H; Karastaneva, A; Schwinger, W; Benesch, M; Sovinz, P; Seidel, M; Sperl, D; Lanz, S; Haxhija, E; Reiterer, F; Sorantin, E; Urban, CE Sirolimus for the treatment of children with various complicated vascular anomalies.
Eur J Pediatr. 2015; 174(12):1579-1584
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Shirsath, N; Mayer, G; Singh, TP; Wolf, P 8-methoxypsoralen plus UVA (PUVA) therapy normalizes signalling of phosphorylated component of mTOR pathway in psoriatic skin of K5.hTGF beta 1 transgenic mice
EXP DERMATOL. 2015; 24(11): 889-891. [OPEN ACCESS]
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Vlahovic, AM; Vlahovic, NS; Haxhija, EQ Sirolimus for the Treatment of a Massive Capillary-Lymphatico-Venous Malformation: A Case Report.
Pediatrics. 2015; 136(2):e513-e516 (- Case Report) [OPEN ACCESS]
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Zitta, S; Schaffellner, S; Gutschi, J; Meinitzer, A; Kniepeiss, D; Artinger, K; Reibnegger, G; Rosenkranz, AR; Wagner, D The Effect of Mammalian Target of Rapamycin Versus Calcineurin Inhibitor-based Immunosuppression on Measured Versus Estimated Glomerular Filtration Rate After Orthotopic Liver Transplantation.
Transplantation. 2015; 99(6):1250-1256
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2014

García-Rodríguez, JL; Barbier-Torres, L; Fernández-Álvarez, S; Gutiérrez-de Juan, V; Monte, MJ; Halilbasic, E; Herranz, D; Álvarez, L; Aspichueta, P; Marín, JJ; Trauner, M; Mato, JM; Serrano, M; Beraza, N; Martínez-Chantar, ML SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
Hepatology. 2014; 59(5):1972-1983 [OPEN ACCESS]
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Lebrun-Julien, F; Bachmann, L; Norrmén, C; Trötzmüller, M; Köfeler, H; Rüegg, MA; Hall, MN; Suter, U Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.
J NEUROSCI. 2014; 34(25): 8432-8448. [OPEN ACCESS]
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Quan, P; Moinfar, F; Kufferath, I; Absenger, M; Kueznik, T; Denk, H; Zatloukal, K; Haybaeck, J Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling.
Anticancer Res. 2014; 34(6):2883-2897
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2013

König, S; Browne, S; Doleschal, B; Schernthaner, M; Poteser, M; Mächler, H; Wittchow, E; Braune, M; Muik, M; Romanin, C; Groschner, K Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.
Am J Physiol Heart Circ Physiol. 2013; 305(11):H1646-H1657 [OPEN ACCESS]
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Ramsey, H; Pilat, N; Hock, K; Klaus, C; Unger, L; Schwarz, C; Baranyi, U; Gattringer, M; Schwaiger, E; Wrba, F; Wekerle, T Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients.
Transpl Int. 2013; 26(2):206-218 [OPEN ACCESS]
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Smolle, E; Taucher, V; Pichler, M; Petru, E; Lax, S; Haybaeck, J Targeting signaling pathways in epithelial ovarian cancer.
Int J Mol Sci. 2013; 14(5):9536-9555 [OPEN ACCESS]
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Yamanaka, K; Petrulionis, M; Lin, S; Gao, C; Galli, U; Richter, S; Winkler, S; Houben, P; Schultze, D; Hatano, E; Schemmer, P Therapeutic potential and adverse events of everolimus for treatment of hepatocellular carcinoma - systematic review and meta-analysis.
Cancer Med. 2013; 2(6):862-871 [OPEN ACCESS]
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Zhu, Y; Pires, KM; Whitehead, KJ; Olsen, CD; Wayment, B; Zhang, YC; Bugger, H; Ilkun, O; Litwin, SE; Thomas, G; Kozma, SC; Abel, ED Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.
PLoS One. 2013; 8(1): e54221-e54221. [OPEN ACCESS]
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2012

Grunewald, TGP; Greulich, N; Kontny, U; Fruhwald, M; Rutkowski, S; Kordes, U; Scheurlen, W; Schmidt, W; Stachel, D; Metzler, M; Mittler, U; Graf, N; Benesch, M; Burdach, S Targeted Therapeutics in Treatment of Children and Young Adults with Solid Tumors: an Expert Survey and Review of the Literature
Klin Padiatr. 2012; 224(3):124-131
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Kirsch, AH; Riegelbauer, V; Tagwerker, A; Rudnicki, M; Rosenkranz, AR; Eller, K The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response.
Am J Physiol Renal Physiol. 2012; 303(4):F569-F575 [OPEN ACCESS]
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2011

Hildebrandt, GC; Fazekas, T; Lawitschka, A; Bertz, H; Greinix, H; Halter, J; Pavletic, SZ; Holler, E; Wolff, D Diagnosis and treatment of pulmonary chronic GVHD: report from the consensus conference on clinical practice in chronic GVHD.
Bone Marrow Transplant. 2011; 46(10): 1283-1295.
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Morselli, E; Shen, S; Ruckenstuhl, C; Bauer, MA; Mariño, G; Galluzzi, L; Criollo, A; Michaud, M; Maiuri, MC; Chano, T; Madeo, F; Kroemer, G p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.
Cell Cycle. 2011; 10(16):2763-2769 [OPEN ACCESS]
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Pilat, N; Klaus, C; Gattringer, M; Jaeckel, E; Wrba, F; Golshayan, D; Baranyi, U; Wekerle, T Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model.
Transplantation. 2011; 92(3):280-288
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2010

Pilat, N; Baranyi, U; Klaus, C; Jaeckel, E; Mpofu, N; Wrba, F; Golshayan, D; Muehlbacher, F; Wekerle, T Treg-therapy allows mixed chimerism and transplantation tolerance without cytoreductive conditioning.
Am J Transplant. 2010; 10(4):751-762 [OPEN ACCESS]
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Prager, GW; Lackner, EM; Krauth, MT; Unseld, M; Poettler, M; Laffer, S; Cerny-Reiterer, S; Lamm, W; Kornek, GV; Binder, BR; Zielinski, CC; Valent, P Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab.
Mol Oncol. 2010; 4(2): 150-160. [OPEN ACCESS]
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2009

Ploner, F; Eisterer, W Treatment of extensive disease
Wien Med Wochenschr. 2009; 159(15-16): 403-407.
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2008

Hochegger, K; Jansky, GL; Soleiman, A; Wolf, AM; Tagwerker, A; Seger, C; Griesmacher, A; Mayer, G; Rosenkranz, AR Differential effects of rapamycin in anti-GBM glomerulonephritis.
J Am Soc Nephrol. 2008; 19(8):1520-1529 [OPEN ACCESS]
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Strnad, P; Zatloukal, K; Stumptner, C; Kulaksiz, H; Denk, H Mallory-Denk-bodies: lessons from keratin-containing hepatic inclusion bodies.
Biochim Biophys Acta. 2008; 1782(12): 764-774. [OPEN ACCESS]
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2007

Bonatti, H; Brandacher, G; Boesmueller, C; Cont, M; Hengster, P; Rosenkranz, AR; Krugmann, J; Margreiter, R Hemolytic uremic syndrome following Campath-1H induction.
Transpl Int. 2007; 20(4):386-389 (- Case Report)
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Kidd, M; Eick, GN; Modlin, IM; Pfragner, R; Champaneria, MC; Murren, J Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin.
J MOLECULAR ENDOCRINOL. 2007; 38(1-2): 181-192. [OPEN ACCESS]
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2006

Mehrabi, A; Fonouni, H; Kashfi, A; Schmied, BM; Morath, Ch; Sadeghi, M; Schemmer, P; Encke, J; Sauer, P; Zeier, M; Weitz, J; Büchler, MW; Schmidt, J The role and value of sirolimus administration in kidney and liver transplantation.
Clin Transplant. 2006; 20 Suppl 17(2):30-43
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Schirmer, M; Duftner, C; Seiler, R; Dejaco, C; Fraedrich, G Abdominal aortic aneurysms: an underestimated type of immune-mediated large vessel arteritis?
Curr Opin Rheumatol. 2006; 18(1): 48-53.
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2003

Pokrajac, B; Wolfram, R; Lileg, B; Minar, E Endovascular Brachytherapy in Peripheral Arteries: Solution for Restenosis or False Hope?
Curr Treat Options Cardiovasc Med. 2003; 5(2):121-126
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