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Search Items: CONTRACTILITY, . hits: 155

2022

Abdellatif, M; Eisenberg, T; Heberle, AM; Thedieck, K; Kroemer, G; Sedej, S Cardiac PI3K p110 alpha attenuation delays aging and extends lifespan
CELL STRESS. 2022; 6(8): 72-75. Doi: 10.15698/cst2022.08.270 [OPEN ACCESS]
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Eaton, DM; Martin, TG; Kasa, M; Djalinac, N; Ljubojevic-Holzer, S; Von, Lewinski, D; Pöttler, M; Kampaengsri, T; Krumphuber, A; Scharer, K; Maechler, H; Zirlik, A; McKinsey, TA; Kirk, JA; Houser, SR; Rainer, PP; Wallner, M HDAC Inhibition Regulates Cardiac Function by Increasing Myofilament Calcium Sensitivity and Decreasing Diastolic Tension.
Pharmaceutics. 2022; 14(7): Doi: 10.3390/pharmaceutics14071509 [OPEN ACCESS]
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Koyani, CN; Scheruebel, S; Jin, G; Kolesnik, E; Zorn-Pauly, K; Mächler, H; Hoefler, G; von, Lewinski, D; Heinzel, FR; Pelzmann, B; Malle, E Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes.
Antioxidants (Basel). 2021; 11(1): Doi: 10.3390/antiox11010025 [OPEN ACCESS]
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Kremer, N; Rako, Z; Douschan, P; Gall, H; Ghofrani, HA; Grimminger, F; Guth, S; Naeije, R; Rieth, A; Schulz, R; Seeger, W; Tedford, RJ; Vadász, I; Vanderpool, R; Wiedenroth, CB; Richter, MJ; Tello, K Unmasking right ventricular-arterial uncoupling during fluid challenge in pulmonary hypertension.
J Heart Lung Transplant. 2022; 41(3):345-355 Doi: 10.1016/j.healun.2021.11.019
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Mabotuwana, NS; Rech, L; Lim, J; Hardy, SA; Murtha, LA; Rainer, PP; Boyle, AJ Paracrine Factors Released by Stem Cells of Mesenchymal Origin and their Effects in Cardiovascular Disease: A Systematic Review of Pre-clinical Studies.
Stem Cell Rev Rep. 2022; 18(8):2606-2628 Doi: 10.1007/s12015-022-10429-6 [OPEN ACCESS]
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2021

Augustin, CM; Gsell, MAF; Karabelas, E; Willemen, E; Prinzen, FW; Lumens, J; Vigmond, EJ; Plank, G A computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation.
Comput Methods Appl Mech Eng. 2021; 386:114092 Doi: 10.1016/j.cma.2021.114092 [OPEN ACCESS]
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Cantinotti, M; Marchese, P; Scalese, M; Medino, P; Jani, V; Franchi, E; Vitali, P; Santoro, G; Viacava, C; Assanta, N; Kutty, S; Koestenberger, M; Giordano, R Left Ventricular Systolic Impairment after Pediatric Cardiac Surgery Assessed by STE Analysis.
Healthcare (Basel). 2021; 9(10): Doi: 10.3390/healthcare9101338 [OPEN ACCESS]
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Cellini, A; Höfler, D; Arias-Loza, PA; Bandleon, S; Langsenlehner, T; Kohlhaas, M; Maack, C; Bauer, WR; Eder-Negrin, P The α2-isoform of the Na⁺/K⁺-ATPase protects against pathological remodeling and β-adrenergic desensitization after myocardial infarction.
Am J Physiol Heart Circ Physiol. 2021; 321(4):H650-H662 Doi: 10.1152/ajpheart.00808.2020
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Jin, G; Manninger, M; Adelsmayr, G; Schwarzl, M; Alogna, A; Schönleitner, P; Zweiker, D; Blaschke, F; Sherif, M; Radulovic, S; Wakula, P; Schauer, S; Höfler, G; Reiter, U; Reiter, G; Post, H; Scherr, D; Acsai, K; Antoons, G; Pieske, B; Heinzel, FR Cellular contribution to left and right atrial dysfunction in chronic arterial hypertension in pigs.
ESC Heart Fail. 2021; 8(1):151-161 Doi: 10.1002/ehf2.13087 [OPEN ACCESS]
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Manning, EP; Ramachandra, AB; Schupp, JC; Cavinato, C; Raredon, MSB; Bärnthaler, T; Cosme, C; Singh, I; Tellides, G; Kaminski, N; Humphrey, JD Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data.
Front Physiol. 2021; 12:726253 Doi: 10.3389/fphys.2021.726253 [OPEN ACCESS]
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Weixler, V; Lapusca, R; Grangl, G; Guariento, A; Saeed, MY; Cowan, DB; Del Nido, PJ; McCully, JD; Friehs, I Autogenous mitochondria transplantation for treatment of right heart failure.
J Thorac Cardiovasc Surg. 2021; 162(1):e111-e121-e111-e121 Doi: 10.1016/j.jtcvs.2020.08.011
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2020

Gross, C; Fresiello, L; Schlöglhofer, T; Dimitrov, K; Marko, C; Maw, M; Meyns, B; Wiedemann, D; Zimpfer, D; Schima, H; Moscato, F Hemodynamic exercise responses with a continuous-flow left ventricular assist device: Comparison of patients' response and cardiorespiratory simulations.
PLoS One. 2020; 15(3):e0229688 Doi: 10.1371/journal.pone.0229688 [OPEN ACCESS]
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Gross, C; Moscato, F; Schlöglhofer, T; Maw, M; Meyns, B; Marko, C; Wiedemann, D; Zimpfer, D; Schima, H; Fresiello, L LVAD speed increase during exercise, which patients would benefit the most? A simulation study.
Artif Organs. 2020; 44(3):239-247 Doi: 10.1111/aor.13569
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Inampudi, C; Tedford, RJ; Hemnes, AR; Hansmann, G; Bogaard, HJ; Koestenberger, M; Lang, IM; Brittain, EL Treatment of right ventricular dysfunction and heart failure in pulmonary arterial hypertension.
Cardiovasc Diagn Ther. 2020; 10(5):1659-1674 Doi: 10.21037/cdt-20-348 [OPEN ACCESS]
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Koyani, CN; Plastira, I; Sourij, H; Hallström, S; Schmidt, A; Rainer, PP; Bugger, H; Frank, S; Malle, E; von, Lewinski, D Empagliflozin protects heart from inflammation and energy depletion via AMPK activation.
Pharmacol Res. 2020; 158:104870 Doi: 10.1016/j.phrs.2020.104870
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Papp, Z; Agostoni, P; Alvarez, J; Bettex, D; Bouchez, S; Brito, D; Černý, V; Comin-Colet, J; Crespo-Leiro, MG; Delgado, JF; Édes, I; Eremenko, AA; Farmakis, D; Fedele, F; Fonseca, C; Fruhwald, S; Girardis, M; Guarracino, F; Harjola, VP; Heringlake, M; Herpain, A; Heunks, LM; Husebye, T; Ivancan, V; Karason, K; Kaul, S; Kivikko, M; Kubica, J; Masip, J; Matskeplishvili, S; Mebazaa, A; Nieminen, MS; Oliva, F; Papp, JG; Parissis, J; Parkhomenko, A; Põder, P; Pölzl, G; Reinecke, A; Ricksten, SE; Riha, H; Rudiger, A; Sarapohja, T; Schwinger, RH; Toller, W; Tritapepe, L; Tschöpe, C; Wikström, G; von Lewinski, D; Vrtovec, B; Pollesello, P Levosimendan Efficacy and Safety: 20 years of SIMDAX in Clinical Use.
Card Fail Rev. 2020; 6(1): e19-e19. Doi: 10.15420/cfr.2020.03 [OPEN ACCESS]
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Papp, Z; Agostoni, P; Alvarez, J; Bettex, D; Bouchez, S; Brito, D; Černý, V; Comin-Colet, J; Crespo-Leiro, MG; Delgado, JF; Édes, I; Eremenko, AA; Farmakis, D; Fedele, F; Fonseca, C; Fruhwald, S; Girardis, M; Guarracino, F; Harjola, VP; Heringlake, M; Herpain, A; Heunks, LMA; Husebye, T; Ivancan, V; Karason, K; Kaul, S; Kivikko, M; Kubica, J; Masip, J; Matskeplishvili, S; Mebazaa, A; Nieminen, MS; Oliva, F; Papp, JG; Parissis, J; Parkhomenko, A; Põder, P; Pölzl, G; Reinecke, A; Ricksten, SE; Riha, H; Rudiger, A; Sarapohja, T; Schwinger, RHG; Toller, W; Tritapepe, L; Tschöpe, C; Wikström, G; Lewinski, DV; Vrtovec, B; Pollesello, P Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use.
J Cardiovasc Pharmacol. 2020; 76(1):4-22 Doi: 10.1097/FJC.0000000000000859 [OPEN ACCESS]
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Schnieder, J; Mamazhakypov, A; Birnhuber, A; Wilhelm, J; Kwapiszewska, G; Ruppert, C; Markart, P; Wujak, L; Rubio, K; Barreto, G; Schaefer, L; Wygrecka, M Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores.
Matrix Biol. 2020; 88:69-88 Doi: 10.1016/j.matbio.2019.12.001
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Wróbel, A; Serefko, A; Szopa, A; Ulrich, D; Poleszak, E; Rechberger, T O-1602, an Agonist of Atypical Cannabinoid Receptors GPR55, Reverses the Symptoms of Depression and Detrusor Overactivity in Rats Subjected to Corticosterone Treatment.
Front Pharmacol. 2020; 11:1002-1002 Doi: 10.3389/fphar.2020.01002 [OPEN ACCESS]
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2019

Agostoni, P; Farmakis, DT; García-Pinilla, JM; Harjola, VP; Karason, K; von Lewinski, D; Parissis, J; Pollesello, P; Pölzl, G; Recio-Mayoral, A; Reinecke, A; Yerly, P; Zima, E Haemodynamic Balance in Acute and Advanced Heart Failure: An Expert Perspective on the Role of Levosimendan.
Card Fail Rev. 2019; 5(3):155-161 Doi: 10.15420/cfr.2019.01.R1 [OPEN ACCESS]
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de Lucia, C; Wallner, M; Eaton, DM; Zhao, H; Houser, SR; Koch, WJ Echocardiographic Strain Analysis for the Early Detection of Left Ventricular Systolic/Diastolic Dysfunction and Dyssynchrony in a Mouse Model of Physiological Aging.
J Gerontol A Biol Sci Med Sci. 2019; 74(4):455-461 Doi: 10.1093/gerona/gly139 [OPEN ACCESS]
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Farmakis, D; Agostoni, P; Baholli, L; Bautin, A; Comin-Colet, J; Crespo-Leiro, MG; Fedele, F; García-Pinilla, JM; Giannakoulas, G; Grigioni, F; Gruchała, M; Gustafsson, F; Harjola, VP; Hasin, T; Herpain, A; Iliodromitis, EK; Karason, K; Kivikko, M; Liaudet, L; Ljubas-Maček, J; Marini, M; Masip, J; Mebazaa, A; Nikolaou, M; Ostadal, P; Põder, P; Pollesello, P; Polyzogopoulou, E; Pölzl, G; Tschope, C; Varpula, M; von Lewinski, D; Vrtovec, B; Yilmaz, MB; Zima, E; Parissis, J A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus.
Int J Cardiol. 2019; 297:83-90 Doi: 10.1016/j.ijcard.2019.09.005 [OPEN ACCESS]
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Kolesnik, E; Krainer, T; Wallner, M; Djalinac, N; Verheyen, N; Ablasser, K; Eaton, DM; Rainer, PP; Pelzmann, B; von Lewinski, D Myocardial GLP-1 Receptor Activation in the Presence of Glucose: Strong Partners
INT J PEPT RES THER. 2019; 25(2): 605-612. Doi: 10.1007/s10989-018-9706-9 [OPEN ACCESS]
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2018

Harjola, VP; Giannakoulas, G; von Lewinski, D; Matskeplishvili, S; Mebazaa, A; Papp, Z; Schwinger, RHG; Pollesello, P; Parissis, JT Use of levosimendan in acute heart failure.
Eur Heart J Suppl. 2018; 20(Suppl I): I2-I10. Doi: 10.1093/eurheartj/suy039 [OPEN ACCESS]
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Kiss, A; Shu, H; Hamza, O; Santer, D; Tretter, EV; Yao, S; Markstaller, K; Hallström, S; Podesser, BK; Klein, KU Argon preconditioning enhances postischaemic cardiac functional recovery following cardioplegic arrest and global cold ischaemia.
Eur J Cardiothorac Surg. 2018; 54(3):539-546 Doi: 10.1093/ejcts/ezy104 [OPEN ACCESS]
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Koyani, CN; Trummer, C; Shrestha, N; Scheruebel, S; Bourgeois, B; Plastira, I; Kickmaier, S; Sourij, H; Rainer, PP; Madl, T; Sattler, W; Pelzmann, B; Malle, E; von Lewinski, D Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Front Physiol. 2018; 9:1622-1622 Doi: 10.3389/fphys.2018.01622 [OPEN ACCESS]
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Kukolj, T; Trivanović, D; Djordjević, IO; Mojsilović, S; Krstić, J; Obradović, H; Janković, S; Santibanez, JF; Jauković, A; Bugarski, D Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling.
J Cell Physiol. 2018; 233(1): 447-462. Doi: 10.1002/jcp.25904
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Schneider, C; Wallner, M; Kolesnik, E; Herbst, V; Mächler, H; Pichler, M; von Lewinski, D; Sedej, S; Rainer, PP The Anti-Cancer Multikinase Inhibitor Sorafenib Impairs Cardiac Contractility by Reducing Phospholamban Phosphorylation and Sarcoplasmic Calcium Transients.
Sci Rep. 2018; 8(1):5295-5295 Doi: 10.1038/s41598-018-23630-w [OPEN ACCESS]
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2017

Koyani, CN; Kolesnik, E; Wölkart, G; Shrestha, N; Scheruebel, S; Trummer, C; Zorn-Pauly, K; Hammer, A; Lang, P; Reicher, H; Maechler, H; Groschner, K; Mayer, B; Rainer, PP; Sourij, H; Sattler, W; Malle, E; Pelzmann, B; von, Lewinski, D Dipeptidyl peptidase-4 independent cardiac dysfunction links saxagliptin to heart failure.
Biochem Pharmacol. 2017; 145:64-80 Doi: 10.1016/j.bcp.2017.08.021 [OPEN ACCESS]
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Taschler, U; Hasenoehrl, C; Storr, M; Schicho, R Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance.
Handb Exp Pharmacol. 2017; 239(6):343-362 Doi: 10.1007/164_2016_105
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Wallner, M; Khafaga, M; Kolesnik, E; Vafiadis, A; Schwantzer, G; Eaton, DM; Curcic, P; Köstenberger, M; Knez, I; Rainer, PP; Pichler, M; Pieske, B; Lewinski, DV Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium.
Oncotarget. 2017; 8(30):49264-49274 Doi: 10.18632/oncotarget.17540 [OPEN ACCESS]
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2016

Alogna, A; Manninger, M; Schwarzl, M; Zirngast, B; Steendijk, P; Verderber, J; Zweiker, D; Maechler, H; Pieske, BM; Post, H Inotropic Effects of Experimental Hyperthermia and Hypothermia on Left Ventricular Function in Pigs-Comparison With Dobutamine.
Crit Care Med. 2016; 44(3):e158-67 Doi: 10.1097/CCM.0000000000001358
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Crnkovic, S; Schmidt, A; Egemnazarov, B; Wilhelm, J; Marsh, LM; Ghanim, B; Klepetko, W; Olschewski, A; Olschewski, H; Kwapiszewska, G Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol. 2016; 311(1):L59-L73 Doi: 10.1152/ajplung.00381.2015 [OPEN ACCESS]
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Koestenberger, M; Apitz, C; Abdul-Khaliq, H; Hansmann, G Transthoracic echocardiography for the evaluation of children and adolescents with suspected or confirmed pulmonary hypertension. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and D6PK.
Heart. 2016; 102 Suppl 2(6):ii14-ii22 Doi: 10.1136/heartjnl-2014-307200 [OPEN ACCESS]
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Müller-Edenborn, B; Kania, G; Osto, E; Jakob, P; Krasniqi, N; Beck-Schimmer, B; Blyszczuk, P; Eriksson, U Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.
PLoS One. 2016; 11(5):e0154699 Doi: 10.1371/journal.pone.0154699 [OPEN ACCESS]
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Patel, K; Rössler, A; Lackner, HK; Trozic, I; Laing, C; Lorr, D; Green, DA; Hinghofer-Szalkay, H; Goswami, N Effect of postural changes on cardiovascular parameters across gender.
Medicine (Baltimore). 2016; 95(28):e4149-e4149 Doi: 10.1097/MD.0000000000004149 [OPEN ACCESS]
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Reiter, U; Reiter, G; Manninger, M; Adelsmayr, G; Schipke, J; Alogna, A; Rajces, A; Stalder, AF; Greiser, A; Mühlfeld, C; Scherr, D; Post, H; Pieske, B; Fuchsjäger, M Early-stage heart failure with preserved ejection fraction in the pig: a cardiovascular magnetic resonance study.
J Cardiovasc Magn Reson. 2016; 18(1):63 Doi: 10.1186/s12968-016-0283-9 [OPEN ACCESS]
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Toth, GG; Vanderheyden, M; Bartunek, J Novel device-based interventional strategies for advanced heart failure.
Postepy Kardiol Interwencyjnej. 2016; 12(1):13-16 Doi: 10.5114/pwki.2016.56944 [OPEN ACCESS]
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Wallner, M; Duran, JM; Mohsin, S; Troupes, CD; Vanhoutte, D; Borghetti, G; Vagnozzi, RJ; Gross, P; Yu, D; Trappanese, DM; Kubo, H; Toib, A; Sharp, TE; Harper, SC; Volkert, MA; Starosta, T; Feldsott, EA; Berretta, RM; Wang, T; Barbe, MF; Molkentin, JD; Houser, SR Acute Catecholamine Exposure Causes Reversible Myocyte Injury Without Cardiac Regeneration.
Circ Res. 2016; 119(7):865-879 Doi: 10.1161/CIRCRESAHA.116.308687 [OPEN ACCESS]
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Zach, B; Hofer, E; Asslaber, M; Ahammer, H Automated Texture Analysis and Determination of Fibre Orientation of Heart Tissue: A Morphometric Study.
PLoS One. 2016; 11(8):e0160735-e0160735 Doi: 10.1371/journal.pone.0160735 [OPEN ACCESS]
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Zittermann, A; Ernst, JB; Pilz, S; Dreier, J; Kuhn, J; Knabbe, C; Gummert, JF; Morshuis, M; Milting, H Calciotropic and Phosphaturic Hormones in End-Stage Heart Failure Patients Supported by a Left-Ventricular Assist Device.
PLoS One. 2016; 11(10):e0164459-e0164459 Doi: 10.1371/journal.pone.0164459 [OPEN ACCESS]
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2015

Braun, M; Hettinger, N; Koentges, C; Pfeil, K; Cimolai, MC; Hoffmann, MM; Osterholt, M; Doenst, T; Bode, C; Bugger, H Myocardial mitochondrial and contractile function are preserved in mice lacking adiponectin.
PLoS One. 2015; 10(3): e0119416-e0119416. Doi: 10.1371/journal.pone.0119416 [OPEN ACCESS]
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Doleschal, B; Primessnig, U; Wölkart, G; Wolf, S; Schernthaner, M; Lichtenegger, M; Glasnov, TN; Kappe, CO; Mayer, B; Antoons, G; Heinzel, F; Poteser, M; Groschner, K TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Cardiovasc Res. 2015; 106(1):163-173 Doi: 10.1093/cvr/cvv022 [OPEN ACCESS]
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Egemnazarov, B; Schmidt, A; Crnkovic, S; Sydykov, A; Nagy, BM; Kovacs, G; Weissmann, N; Olschewski, H; Olschewski, A; Kwapiszewska, G; Marsh, LM Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography.
J Am Soc Echocardiogr. 2015; 28(7):828-843 Doi: 10.1016/j.echo.2015.02.014
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Gregory, AD; Kliment, CR; Metz, HE; Kim, KH; Kargl, J; Agostini, BA; Crum, LT; Oczypok, EA; Oury, TA; Houghton, AM Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.
J Leukoc Biol. 2015; 98(2): 143-152. Doi: 10.1189/jlb.3HI1014-493R [OPEN ACCESS]
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Rungatscher, A; Hallström, S; Linardi, D; Milani, E; Gasser, H; Podesser, BK; Scarabelli, TM; Luciani, GB; Faggian, G S-nitroso human serum albumin attenuates pulmonary hypertension, improves right ventricular-arterial coupling, and reduces oxidative stress in a chronic right ventricle volume overload model.
J Heart Lung Transplant. 2015; 34(3):479-488 Doi: 10.1016/j.healun.2014.09.041
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Taschler, U; Eichmann, TO; Radner, FP; Grabner, GF; Wolinski, H; Storr, M; Lass, A; Schicho, R; Zimmermann, R Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity.
Br J Pharmacol. 2015; 172(17):4419-29 Doi: 10.1111/bph.13224 [OPEN ACCESS]
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Wallner, M; Kolesnik, E; Ablasser, K; Khafaga, M; Wakula, P; Ljubojevic, S; Thon-Gutschi, EM; Sourij, H; Kapl, M; Edmunds, NJ; Kuzmiski, JB; Griffith, DA; Knez, I; Pieske, B; von Lewinski, D Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium: GLP-1R mediated effects in human myocardium.
J Mol Cell Cardiol. 2015; 89(Pt B):365-375 Doi: 10.1016/j.yjmcc.2015.09.018
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2014

Cochet, H; Scherr, D; Zellerhoff, S; Sacher, F; Derval, N; Denis, A; Knecht, S; Komatsu, Y; Montaudon, M; Laurent, F; Pieske, BM; Hocini, M; Haïssaguerre, M; Jaïs, P Atrial structure and function 5 years after successful ablation for persistent atrial fibrillation: an MRI study.
J Cardiovasc Electrophysiol. 2014; 25(7):671-679 Doi: 10.1111/jce.12449
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Granegger, M; Schima, H; Zimpfer, D; Moscato, F Assessment of aortic valve opening during rotary blood pump support using pump signals.
Artif Organs. 2014; 38(4):290-7 Doi: 10.1111/aor.12167
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