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Search Items: SIGNAL TRANSDUCTION - , . hits: 510

2020

Golob-Schwarzl, N; Puchas, P; Gogg-Kamerer, M; Weichert, W; Göppert, B; Haybaeck, J New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.
Anticancer Res. 2020; 40(6):3109-3118
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2019

Kukolj, T; Trivanović, D; Mojsilović, S; Okić Djordjević, I; Obradović, H; Krstić, J; Jauković, A; Bugarski, D IL-33 guides osteogenesis and increases proliferation and pluripotency marker expression in dental stem cells.
Cell Prolif. 2019; 52(1): e12533-e12533. [OPEN ACCESS]
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Willecke, F; Rupprecht, B; Gissler, MC; Pfeiffer, K; Anto-Michel, N; Stachon, P; Wolf, D; Hilgendorf, I; Hoppe, N; Bode, C; Zirlik, A Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation.
J VASC RES. 2019; 56(6): 308-319.
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2018

Bourgeois, B; Madl, T Regulation of cellular senescence via the FOXO4-p53 axis.
FEBS Lett. 2018; 592(12):2083-2097 [OPEN ACCESS]
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Groschner, K; Tiapko, O Revelation of an enigmatic signaling machinery-First insights into the mammalian TRPC architecture.
Cell Calcium. 2018; 74(9):144-146
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Jahanafrooz, Z; Stallinger, A; Anders, I; Kleinegger, F; Lohberger, B; Durchschein, C; Bauer, R; Deutsch, A; Rinner, B; Kretschmer, N Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
Phytomedicine. 2018; 49(11):32-40
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Kretschmer, N; Deutsch, A; Durchschein, C; Rinner, B; Stallinger, A; Higareda-Almaraz, JC; Scheideler, M; Lohberger, B; Bauer, R Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction.
Molecules. 2018; 23(11): [OPEN ACCESS]
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Kukolj, T; Trivanović, D; Djordjević, IO; Mojsilović, S; Krstić, J; Obradović, H; Janković, S; Santibanez, JF; Jauković, A; Bugarski, D Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling.
J Cell Physiol. 2018; 233(1): 447-462.
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Mutgan, AC; Besikcioglu, HE; Wang, S; Friess, H; Ceyhan, GO; Demir, IE Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer.
Mol Cancer. 2018; 17(1): 66-66. [OPEN ACCESS]
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Rengachari, S; Groiss, S; Devos, JM; Caron, E; Grandvaux, N; Panne, D Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.
Proc Natl Acad Sci U S A. 2018; 115(4): E601-E609. [OPEN ACCESS]
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Segerer, G; Engelmann, D; Kaestner, A; Trötzmüller, M; Köfeler, H; Stigloher, C; Thiele, C; Jeanclos, E; Gohla, A A phosphoglycolate phosphatase/AUM-dependent link between triacylglycerol turnover and epidermal growth factor signaling.
Biochim Biophys Acta. 2018; 1863(6):584-594
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Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 [OPEN ACCESS]
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2017

Arzt, L; Halbwedl, I; Gogg-Kamerer, M; Popper, HH Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma.
Pathol Oncol Res. 2017; 23(3):595-605 [OPEN ACCESS]
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Buerger, C; Shirsath, N; Lang, V; Berard, A; Diehl, S; Kaufmann, R; Boehncke, WH; Wolf, P Inflammation dependent mTORC1 signaling interferes with the switch from keratinocyte proliferation to differentiation.
PLoS One. 2017; 12(7):e0180853-e0180853 [OPEN ACCESS]
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Charoensin, S; Eroglu, E; Opelt, M; Bischof, H; Madreiter-Sokolowski, CT; Kirsch, A; Depaoli, MR; Frank, S; Schrammel, A; Mayer, B; Waldeck-Weiermair, M; Graier, WF; Malli, R Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).
Free Radic Biol Med. 2017; 102(1):248-259 [OPEN ACCESS]
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Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285 [OPEN ACCESS]
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Didiasova, M; Singh, R; Wilhelm, J; Kwapiszewska, G; Wujak, L; Zakrzewicz, D; Schaefer, L; Markart, P; Seeger, W; Lauth, M; Wygrecka, M Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors.
FASEB J. 2017; 31(5):1916-1928
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El Agha, E; Moiseenko, A; Kheirollahi, V; De Langhe, S; Crnkovic, S; Kwapiszewska, G; Szibor, M; Kosanovic, D; Schwind, F; Schermuly, RT; Henneke, I; MacKenzie, B; Quantius, J; Herold, S; Ntokou, A; Ahlbrecht, K; Braun, T; Morty, RE; Günther, A; Seeger, W; Bellusci, S Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.
Cell Stem Cell. 2017; 20(2):261-273 [OPEN ACCESS]
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Fasching, P; Stradner, M; Graninger, W; Dejaco, C; Fessler, J Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders.
Molecules. 2017; 22(1): [OPEN ACCESS]
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Fechter, K; Dorronsoro, A; Jakobsson, E; Ferrin, I; Lang, V; Sepulveda, P; Pennington, DJ; Trigueros, C IFNγ Regulates Activated Vδ2+ T Cells through a Feedback Mechanism Mediated by Mesenchymal Stem Cells.
PLoS One. 2017; 12(1):e0169362-e0169362 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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González-Vela, MDC; Curiel-Olmo, S; Derdak, S; Beltran, S; Santibañez, M; Martínez, N; Castillo-Trujillo, A; Gut, M; Sánchez-Pacheco, R; Almaraz, C; Cereceda, L; Llombart, B; Agraz-Doblas, A; Revert-Arce, J; López Guerrero, JA; Mollejo, M; Marrón, PI; Ortiz-Romero, P; Fernandez-Cuesta, L; Varela, I; Gut, I; Cerroni, L; Piris, MÁ; Vaqué, JP Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas.
J Invest Dermatol. 2017; 137(1):197-206 [OPEN ACCESS]
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Gourinchas, G; Etzl, S; Göbl, C; Vide, U; Madl, T; Winkler, A Long-range allosteric signaling in red light-regulated diguanylyl cyclases.
SCI ADV. 2017; 3(3): e1602498-e1602498. [OPEN ACCESS]
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Grabner, GF; Zimmermann, R; Schicho, R; Taschler, U Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.
Pharmacol Ther. 2017; 175:35-46 [OPEN ACCESS]
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Groschner, K; Shrestha, N; Fameli, N Cardiovascular and Hemostatic Disorders: SOCE in Cardiovascular Cells: Emerging Targets for Therapeutic Intervention.
Adv Exp Med Biol. 2017; 993: 473-503.
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Hasenoehrl, C; Storr, M; Schicho, R Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go?
Expert Rev Gastroenterol Hepatol. 2017; 11(4):329-337 [OPEN ACCESS]
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Hillmeister, P; Buschmann, E; Persson, PB; Bondke Persson, A Exercise for healthy flow.
Acta Physiol (Oxf). 2017; 219(1): 3-8.
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Lin, S; Hoffmann, K; Gao, C; Petrulionis, M; Herr, I; Schemmer, P Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma.
J PINEAL RES. 2017; 62(3):
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Liu, X; Latkolik, S; Atanasov, AG; Kunert, O; Pferschy-Wenzig, EM; Heiss, EH; Malainer, C; Schinkovitz, A; Kollroser, M; Dirsch, VM; Bauer, R Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF-κB Inhibitors.
Planta Med. 2017; 83(14-15):1242-1250 [OPEN ACCESS]
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Madreiter-Sokolowski, CT; Sokolowski, AA; Graier, WF Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria.
Nutrients. 2017; 9(10): [OPEN ACCESS]
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Mayr, C; Ocker, M; Ritter, M; Pichler, M; Neureiter, D; Kiesslich, T Biliary tract cancer stem cells - translational options and challenges.
World J Gastroenterol. 2017; 23(14):2470-2482 [OPEN ACCESS]
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Mehta, AK; Hua, K; Whipple, W; Nguyen, MT; Liu, CT; Haybaeck, J; Weidhaas, J; Settleman, J; Singh, A Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells.
Sci Signal. 2017; 10(496): [OPEN ACCESS]
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Mueller, KM; Hartmann, K; Kaltenecker, D; Vettorazzi, S; Bauer, M; Mauser, L; Amann, S; Jall, S; Fischer, K; Esterbauer, H; Müller, TD; Tschöp, MH; Magnes, C; Haybaeck, J; Scherer, T; Bordag, N; Tuckermann, JP; Moriggl, R Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Diabetes. 2017; 66(2):272-286 [OPEN ACCESS]
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Paw, M; Borek, I; Wnuk, D; Ryszawy, D; Piwowarczyk, K; Kmiotek, K; Wójcik-Pszczoła, KA; Pierzchalska, M; Madeja, Z; Sanak, M; Błyszczuk, P; Michalik, M; Czyż, J Connexin43 Controls the Myofibroblastic Differentiation of Bronchial Fibroblasts from Patients with Asthma.
Am J Respir Cell Mol Biol. 2017; 57(1):100-110
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Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 [OPEN ACCESS]
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 [OPEN ACCESS]
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Rashed, MH; Kanlikilicer, P; Rodriguez-Aguayo, C; Pichler, M; Bayraktar, R; Bayraktar, E; Ivan, C; Filant, J; Silva, A; Aslan, B; Denizli, M; Mitra, R; Ozpolat, B; Calin, GA; Sood, AK; Abd-Ellah, MF; Helal, GK; Berestein, GL Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget. 2017; 8(12):20145-20164 [OPEN ACCESS]
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Richtig, G; Richtig, E; Kashofer, K; Koch, L; Winter, G; Hoefler, G; Pichler, M; Ehall, B; Grübler, MR; Heinemann, A; Aigelsreiter, A Testing and clinical implications for non-V600 BRAF mutations in metastatic NRASmt melanoma.
Br J Dermatol. 2017; 177(3):860-861
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Riedl, A; Schlederer, M; Pudelko, K; Stadler, M; Walter, S; Unterleuthner, D; Unger, C; Kramer, N; Hengstschläger, M; Kenner, L; Pfeiffer, D; Krupitza, G; Dolznig, H Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses.
J Cell Sci. 2017; 130(1):203-218 [OPEN ACCESS]
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Schanza, LM; Seles, M; Stotz, M; Fosselteder, J; Hutterer, GC; Pichler, M; Stiegelbauer, V MicroRNAs Associated with Von Hippel-Lindau Pathway in Renal Cell Carcinoma: A Comprehensive Review.
Int J Mol Sci. 2017; 18(11): [OPEN ACCESS]
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Taschler, U; Hasenoehrl, C; Storr, M; Schicho, R Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance.
Handb Exp Pharmacol. 2017; 239(6):343-362
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Thangaratnarajah, C; Dinger, K; Vohlen, C; Klaudt, C; Nawabi, J; Lopez Garcia, E; Kwapiszewska, G; Dobner, J; Nüsken, KD; van Koningsbruggen-Rietschel, S; von Hörsten, S; Dötsch, J; Alejandre Alcázar, MA Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.
Am J Physiol Lung Cell Mol Physiol. 2017; 313(3):L491-L506 [OPEN ACCESS]
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Windpassinger, C; Piard, J; Bonnard, C; Alfadhel, M; Lim, S; Bisteau, X; Blouin, S; Ali, NB; Ng, AYJ; Lu, H; Tohari, S; Talib, SZA; van Hul, N; Caldez, MJ; Van Maldergem, L; Yigit, G; Kayserili, H; Youssef, SA; Coppola, V; de Bruin, A; Tessarollo, L; Choi, H; Rupp, V; Roetzer, K; Roschger, P; Klaushofer, K; Altmüller, J; Roy, S; Venkatesh, B; Ganger, R; Grill, F; Ben Chehida, F; Wollnik, B; Altunoglu, U; Al Kaissi, A; Reversade, B; Kaldis, P CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
Am J Hum Genet. 2017; 101(3): 391-403. [OPEN ACCESS]
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Wolf, D; Bukosza, N; Engel, D; Poggi, M; Jehle, F; Anto Michel, N; Chen, YC; Colberg, C; Hoppe, N; Dufner, B; Boon, L; Blankenbach, H; Hilgendorf, I; von Zur Muhlen, C; Reinöhl, J; Sommer, B; Marchini, T; Febbraio, MA; Weber, C; Bode, C; Peter, K; Lutgens, E; Zirlik, A Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).
Thromb Haemost. 2017; 117(2):325-338
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Wu, BJ; Li, Y; Ong, KL; Sun, Y; Shrestha, S; Hou, L; Johns, D; Barter, PJ; Rye, KA Reduction of In-Stent Restenosis by Cholesteryl Ester Transfer Protein Inhibition.
ARTERIOSCL THROM VAS. 2017; 37(12): 2333-2341. [OPEN ACCESS]
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Zeitelhofer, M; Adzemovic, MZ; Gomez-Cabrero, D; Bergman, P; Hochmeister, S; N'diaye, M; Paulson, A; Ruhrmann, S; Almgren, M; Tegnér, JN; Ekström, TJ; Guerreiro-Cacais, AO; Jagodic, M Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.
Proc Natl Acad Sci U S A. 2017; 114(9):E1678-E1687 [OPEN ACCESS]
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2016

Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
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Barghash, A; Golob-Schwarzl, N; Helms, V; Haybaeck, J; Kessler, SM Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma.
Oncotarget. 2016; 7(31):49743-49750 [OPEN ACCESS]
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Bengesser, SA; Fuchs, R; Lackner, N; Birner, A; Reininghaus, B; Meier-Allard, N; Stracke, A; Kapfhammer, HP; Reininghaus, EZ; Wallner-Liebmann, S Endoplasmic Reticulum Stress and Bipolar Disorder - Almost Forgotten Therapeutic Drug Targets in the Unfolded Protein Response Pathway Revisited.
CNS Neurol Disord Drug Targets. 2016; 15(4):403-413
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Birner, P; Heider, S; Petzelbauer, P; Wolf, P; Kornauth, C; Kuroll, M; Merkel, O; Steiner, G; Kishimoto, T; Rose-John, S; Soleiman, A; Moriggl, R; Kenner, L Interleukin-6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosus.
Exp Dermatol. 2016; 25(4):305-310 [OPEN ACCESS]
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