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Search Items: PROTEOMICS, . hits: 126

2023

Berger, N; van, der, Wel, T; Hirschmugl, B; Baernthaler, T; Gindlhuber, J; Fawzy, N; Eichmann, T; Birner-Gruenberger, R; Zimmermann, R; van, der, Stelt, M; Wadsack, C Inhibition of diacylglycerol lipase β modulates lipid and endocannabinoid levels in the ex vivo human placenta.
Front Endocrinol (Lausanne). 2023; 14: 1092024 Doi: 10.3389/fendo.2023.1092024 [OPEN ACCESS]
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Honeder, SE; Tomin, T; Schinagl, M; Pfleger, R; Hoehlschen, J; Darnhofer, B; Schittmayer, M; Birner-Gruenberger, R Research Advances Through Activity-Based Lipid Hydrolase Profiling
ISR J CHEM. 2023; Doi: 10.1002/ijch.202200078
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Kulaj, K; Harger, A; Bauer, M; Caliskan, ÖS; Gupta, TK; Chiang, DM; Milbank, E; Reber, J; Karlas, A; Kotzbeck, P; Sailer, DN; Volta, F; Lutter, D; Prakash, S; Merl-Pham, J; Ntziachristos, V; Hauner, H; Pfaffl, MW; Tschöp, MH; Müller, TD; Hauck, SM; Engel, BD; Gerdes, JM; Pfluger, PT; Krahmer, N; Stemmer, K Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo.
Nat Commun. 2023; 14(1):709 Doi: 10.1038/s41467-023-36148-1 [OPEN ACCESS]
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Schrom, S; Kleinegger, F; Anders, I; Hebesberger, T; Karner, C; Liesinger, L; Birner-Gruenberger, R; Renner, W; Pichler, M; Grillari, R; Aigelsreiter, A; Rinner, B MUG CCArly: A Novel Autologous 3D Cholangiocarcinoma Model Presents an Increased Angiogenic Potential.
Cancers (Basel). 2023; 15(6): Doi: 10.3390/cancers15061757 [OPEN ACCESS]
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2022

Bradić, I; Kuentzel, KB; Honeder, S; Grabner, GF; Vujić, N; Zimmermann, R; Birner-Gruenberger, R; Kratky, D Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases.
Mol Metab. 2022; 61:101510 Doi: 10.1016/j.molmet.2022.101510 [OPEN ACCESS]
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Duffy, EE; Finander, B; Choi, G; Carter, AC; Pritisanac, I; Alam, A; Luria, V; Karger, A; Phu, W; Sherman, MA; Assad, EG; Pajarillo, N; Khitun, A; Crouch, EE; Ganesh, S; Chen, J; Berger, B; Sestan, N; O'Donnell-Luria, A; Huang, EJ; Griffith, EC; Forman-Kay, JD; Moses, AM; Kalish, BT; Greenberg, ME Developmental dynamics of RNA translation in the human brain.
NAT NEUROSCI. 2022; 25(10): 1353-1365. Doi: 10.1038/s41593-022-01164-9 [OPEN ACCESS]
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Galhuber, M; Michenthaler, H; Heininger, C; Reinisch, I; Nössing, C; Krstic, J; Kupper, N; Moyschewitz, E; Auer, M; Heitzer, E; Ulz, P; Birner-Gruenberger, R; Liesinger, L; Lenihan-Geels, GN; Oster, M; Spreitzer, E; Zenezini, Chiozzi, R; Schulz, TJ; Schupp, M; Madl, T; Heck, AJR; Prokesch, A Complementary omics strategies to dissect p53 signaling networks under nutrient stress.
Cell Mol Life Sci. 2022; 79(6):326 Doi: 10.1007/s00018-022-04345-8 [OPEN ACCESS]
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Gindlhuber, J; Schinagl, M; Liesinger, L; Darnhofer, B; Tomin, T; Schittmayer, M; Birner-Gruenberger, R Hepatocyte Proteome Alterations Induced by Individual and Combinations of Common Free Fatty Acids.
Int J Mol Sci. 2022; 23(6): Doi: 10.3390/ijms23063356 [OPEN ACCESS]
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Gindlhuber, J; Tomin, T; Wiesenhofer, F; Zacharias, M; Liesinger, L; Demichev, V; Kratochwill, K; Gorkiewicz, G; Schittmayer, M; Birner-Gruenberger, R Proteomic profiling of end-stage COVID-19 lung biopsies.
Clin Proteomics. 2022; 19(1): 46 Doi: 10.1186/s12014-022-09386-6 [OPEN ACCESS]
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Grossmann, T; Darnhofer, B; Birner-Gruenberger, R; Kirsch, A; Gugatschka, M Descriptive proteomics of paired human vocal fold and buccal mucosa tissue.
Proteomics Clin Appl. 2022; 16(2):e2100050 Doi: 10.1002/prca.202100050 [OPEN ACCESS]
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Holzer, M; Ljubojevic-Holzer, S; Souza, Junior, DR; Stadler, JT; Rani, A; Scharnagl, H; Ronsein, GE; Marsche, G HDL Isolated by Immunoaffinity, Ultracentrifugation, or Precipitation is Compositionally and Functionally Distinct.
J Lipid Res. 2022; 63(12):100307 Doi: 10.1016/j.jlr.2022.100307 [OPEN ACCESS]
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Koser, F; Hobbach, AJ; Abdellatif, M; Herbst, V; Türk, C; Reinecke, H; Krüger, M; Sedej, S; Linke, WA Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment.
Life Sci. 2022; 309:120998 Doi: 10.1016/j.lfs.2022.120998
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Megyesfalvi, Z; Barany, N; Lantos, A; Valko, Z; Pipek, O; Lang, C; Schwendenwein, A; Oberndorfer, F; Paku, S; Ferencz, B; Dezso, K; Fillinger, J; Lohinai, Z; Moldvay, J; Galffy, G; Szeitz, B; Rezeli, M; Rivard, C; Hirsch, FR; Brcic, L; Popper, H; Kern, I; Kovacevic, M; Skarda, J; Mittak, M; Marko-Varga, G; Bogos, K; Renyi-Vamos, F; Hoda, MA; Klikovits, T; Hoetzenecker, K; Schelch, K; Laszlo, V; Dome, B Expression patterns and prognostic relevance of subtype-specific transcription factors in surgically resected small-cell lung cancer: an international multicenter study.
J Pathol. 2022; 257(5):674-686 Doi: 10.1002/path.5922 [OPEN ACCESS]
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2021

Balarastaghi, S; Yazdian-Robati, R; Vahdati, Hasani, F; Hosseinzadeh, H; Abnous, K; Imenshahidi, M; Mohammadzadeh, L; Birner-Gruenberger, R; Razavi, BM Protective Effect of Crocin on Malathion-induced Cardiotoxicity in Rats: A Biochemical, Histopathological and Proteomics Study.
Iran J Pharm Res. 2021; 20(2): 156-172. Doi: 10.22037/ijpr.2020.111836.13385 [OPEN ACCESS]
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Darnhofer, B; Tomin, T; Liesinger, L; Schittmayer, M; Tomazic, PV; Birner-Gruenberger, R Comparative proteomics of common allergenic tree pollens of birch, alder, and hazel.
Allergy. 2021; 76(6):1743-1753 Doi: 10.1111/all.14694 [OPEN ACCESS]
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Ercan, H; Mauracher, LM; Grilz, E; Hell, L; Hellinger, R; Schmid, JA; Moik, F; Ay, C; Pabinger, I; Zellner, M Alterations of the Platelet Proteome in Lung Cancer: Accelerated F13A1 and ER Processing as New Actors in Hypercoagulability.
Cancers (Basel). 2021; 13(9): Doi: 10.3390/cancers13092260 [OPEN ACCESS]
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Gutiérrez, AL; Lindberg, JH; Shevchenko, G; Gustavsson, I; Bergquist, J; Gyllensten, U; Enroth, S Identification of Candidate Protein Biomarkers for CIN2+ Lesions from Self-Sampled, Dried Cervico-Vaginal Fluid Using LC-MS/MS.
Cancers (Basel). 2021; 13(11): Doi: 10.3390/cancers13112592 [OPEN ACCESS]
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Honeder, S; Tomin, T; Nebel, L; Gindlhuber, J; Fritz-Wallace, K; Schinagl, M; Heininger, C; Schittmayer, M; Ghaffari-Tabrizi-Wizsy, N; Birner-Gruenberger, R Adipose Triglyceride Lipase Loss Promotes a Metabolic Switch in A549 Non-Small Cell Lung Cancer Cell Spheroids.
Mol Cell Proteomics. 2021; 20:100095 Doi: 10.1016/j.mcpro.2021.100095 [OPEN ACCESS]
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Ryan, DG; Yang, M; Prag, HA; Blanco, GR; Nikitopoulou, E; Segarra-Mondejar, M; Powell, CA; Young, T; Burger, N; Miljkovic, JL; Minczuk, M; Murphy, MP; von, Kriegsheim, A; Frezza, C Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism.
Elife. 2021; 10: Doi: 10.7554/eLife.72593 [OPEN ACCESS]
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Schinagl, M; Tomin, T; Gindlhuber, J; Honeder, S; Pfleger, R; Schittmayer, M; Trauner, M; Birner-Gruenberger, R Proteomic Changes of Activated Hepatic Stellate Cells.
Int J Mol Sci. 2021; 22(23): Doi: 10.3390/ijms222312782 [OPEN ACCESS]
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Steinberger, S; Karuthedom, George, S; Lauková, L; Weiss, R; Tripisciano, C; Birner-Gruenberger, R; Weber, V; Allmaier, G; Weiss, VU A possible role of gas-phase electrophoretic mobility molecular analysis (nES GEMMA) in extracellular vesicle research.
Anal Bioanal Chem. 2021; 413(30):7341-7352 Doi: 10.1007/s00216-021-03692-y [OPEN ACCESS]
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Tomin, T; Schittmayer, M; Sedej, S; Bugger, H; Gollmer, J; Honeder, S; Darnhofer, B; Liesinger, L; Zuckermann, A; Rainer, PP; Birner-Gruenberger, R Mass Spectrometry-Based Redox and Protein Profiling of Failing Human Hearts.
Int J Mol Sci. 2021; 22(4): Doi: 10.3390/ijms22041787 [OPEN ACCESS]
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Zhang, F; Wang, Y; Chen, G; Li, Z; Xing, X; Putz-Bankuti, C; Stauber, RE; Liu, X; Madl, T Growing Human Hepatocellular Tumors Undergo a Global Metabolic Reprogramming.
Cancers (Basel). 2021; 13(8): Doi: 10.3390/cancers13081980 [OPEN ACCESS]
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2020

Blomme, A; Ford, CA; Mui, E; Patel, R; Ntala, C; Jamieson, LE; Planque, M; McGregor, GH; Peixoto, P; Hervouet, E; Nixon, C; Salji, M; Gaughan, L; Markert, E; Repiscak, P; Sumpton, D; Blanco, GR; Lilla, S; Kamphorst, JJ; Graham, D; Faulds, K; MacKay, GM; Fendt, SM; Zanivan, S; Leung, HY 2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.
Nat Commun. 2020; 11(1):2508 Doi: 10.1038/s41467-020-16126-7 [OPEN ACCESS]
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Gibhardt, CS; Cappello, S; Bhardwaj, R; Schober, R; Kirsch, SA; Bonilla Del Rio, Z; Gahbauer, S; Bochicchio, A; Sumanska, M; Ickes, C; Stejerean-Todoran, I; Mitkovski, M; Alansary, D; Zhang, X; Revazian, A; Fahrner, M; Lunz, V; Frischauf, I; Luo, T; Ezerina, D; Messens, J; Belousov, VV; Hoth, M; Böckmann, RA; Hediger, MA; Schindl, R; Bogeski, I Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry.
Cell Rep. 2020; 33(3):108292-108292 Doi: 10.1016/j.celrep.2020.108292 [OPEN ACCESS]
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Gruber, MM; Hirschmugl, B; Berger, N; Holter, M; Radulović, S; Leitinger, G; Liesinger, L; Berghold, A; Roblegg, E; Birner-Gruenberger, R; Bjelic-Radisic, V; Wadsack, C Plasma proteins facilitates placental transfer of polystyrene particles.
J Nanobiotechnology. 2020; 18(1): 128-128. Doi: 10.1186/s12951-020-00676-5 [OPEN ACCESS]
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Ott, E; Kawaguchi, Y; Kölbl, D; Rabbow, E; Rettberg, P; Mora, M; Moissl-Eichinger, C; Weckwerth, W; Yamagishi, A; Milojevic, T Molecular repertoire of Deinococcus radiodurans after 1 year of exposure outside the International Space Station within the Tanpopo mission.
Microbiome. 2020; 8(1):150-150 Doi: 10.1186/s40168-020-00927-5 [OPEN ACCESS]
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Prasch, J; Bernhart, E; Reicher, H; Kollroser, M; Rechberger, GN; Koyani, CN; Trummer, C; Rech, L; Rainer, PP; Hammer, A; Malle, E; Sattler, W Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21239235 [OPEN ACCESS]
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Schittmayer, M; Vujic, N; Darnhofer, B; Korbelius, M; Honeder, S; Kratky, D; Birner-Gruenberger, R Spatially Resolved Activity-based Proteomic Profiles of the Murine Small Intestinal Lipases.
Mol Cell Proteomics. 2020; 19(12):2104-2114 Doi: 10.1074/mcp.RA120.002171 [OPEN ACCESS]
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Soleyman, NM; Darnhofer, B; Gruenberger, RB; Abnous, K; Borji, H Proteomic analysis of soluble protein extract of adult Toxocara cati.
Comp Immunol Microbiol Infect Dis. 2020; 73(11):101528-101528 Doi: 10.1016/j.cimid.2020.101528
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Streidl, T; Karkossa, I; Segura, Muñoz, RR; Eberl, C; Zaufel, A; Plagge, J; Schmaltz, R; Schubert, K; Basic, M; Schneider, KM; Afify, M; Trautwein, C; Tolba, R; Stecher, B; Doden, HL; Ridlon, JM; Ecker, J; Moustafa, T; von, Bergen, M; Ramer-Tait, AE; Clavel, T The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice.
GUT MICROBES. 2020; 13(1): 1-21. Doi: 10.1080/19490976.2020.1854008 [OPEN ACCESS]
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Tavakkoli, A; Abnous, K; Vahdati Hassani, F; Hosseinzadeh, H; Birner-Gruenberger, R; Mehri, S Alteration of protein profile in cerebral cortex of rats exposed to bisphenol a: a proteomics study.
Neurotoxicology. 2020; 78(2):1-10 Doi: 10.1016/j.neuro.2020.01.013
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Tomazic, PV; Darnhofer, B; Birner-Gruenberger, R Nasal mucus proteome and its involvement in allergic rhinitis.
Expert Rev Proteomics. 2020; 17(3):191-199 Doi: 10.1080/14789450.2020.1748502 [OPEN ACCESS]
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Wallner, M; Eaton, DM; Berretta, RM; Liesinger, L; Schittmayer, M; Gindlhuber, J; Wu, J; Jeong, MY; Lin, YH; Borghetti, G; Baker, ST; Zhao, H; Pfleger, J; Blass, S; Rainer, PP; von Lewinski, D; Bugger, H; Mohsin, S; Graier, WF; Zirlik, A; McKinsey, TA; Birner-Gruenberger, R; Wolfson, MR; Houser, SR HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Sci Transl Med. 2020; 12(525): Doi: 10.1126/scitranslmed.aay7205 [OPEN ACCESS]
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2019

Gugatschka, M; Darnhofer, B; Grossmann, T; Schittmayer, M; Hortobagyi, D; Kirsch, A; Karpf, E; Brcic, L; Birner-Gruenberger, R; Karbiener, M Proteomic Analysis of Vocal Fold Fibroblasts Exposed to Cigarette Smoke Extract: Exploring the Pathophysiology of Reinke's Edema.
Mol Cell Proteomics. 2019; 18(8):1511-1525 Doi: 10.1074/mcp.RA119.001272 [OPEN ACCESS]
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Madreiter-Sokolowski, CT; Waldeck-Weiermair, M; Bourguignon, MP; Villeneuve, N; Gottschalk, B; Klec, C; Stryeck, S; Radulovic, S; Parichatikanond, W; Frank, S; Madl, T; Malli, R; Graier, WF Enhanced inter-compartmental Ca²⁺ flux modulates mitochondrial metabolism and apoptotic threshold during aging.
Redox Biol. 2019; 20:458-466 Doi: 10.1016/j.redox.2018.11.003 [OPEN ACCESS]
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Mokou, M; Klein, J; Makridakis, M; Bitsika, V; Bascands, JL; Saulnier-Blache, JS; Mullen, W; Sacherer, M; Zoidakis, J; Pieske, B; Mischak, H; Roubelakis, MG; Schanstra, JP; Vlahou, A Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease.
EBioMedicine. 2019; 41:91-104 Doi: 10.1016/j.ebiom.2019.02.040 [OPEN ACCESS]
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Pepin, ME; Koentges, C; Pfeil, K; Gollmer, J; Kersting, S; Wiese, S; Hoffmann, MM; Odening, KE; von Zur Mühlen, C; Diehl, P; Stachon, P; Wolf, D; Wende, AR; Bode, C; Zirlik, A; Bugger, H Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1.
Front Endocrinol (Lausanne). 2019; 10(1):872-872 Doi: 10.3389/fendo.2019.00872 [OPEN ACCESS]
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Schilcher, I; Ledinski, G; Radulović, S; Hallström, S; Eichmann, T; Madl, T; Zhang, F; Leitinger, G; Kolb-Lenz, D; Darnhofer, B; Birner-Gruenberger, R; Wadsack, C; Kratky, D; Marsche, G; Frank, S; Cvirn, G Endothelial lipase increases antioxidative capacity of high-density lipoprotein.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1363-1374 Doi: 10.1016/j.bbalip.2019.06.011 [OPEN ACCESS]
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Schumacher, D; Andrieux, G; Boehnke, K; Keil, M; Silvestri, A; Silvestrov, M; Keilholz, U; Haybaeck, J; Erdmann, G; Sachse, C; Templin, M; Hoffmann, J; Boerries, M; Schäfer, R; Regenbrecht, CRA Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.
PLoS Genet. 2019; 15(3):e1008076-e1008076 Doi: 10.1371/journal.pgen.1008076 [OPEN ACCESS]
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2018

Burg, D; Schofield, JPR; Brandsma, J; Staykova, D; Folisi, C; Bansal, A; Nicholas, B; Xian, Y; Rowe, A; Corfield, J; Wilson, S; Ward, J; Lutter, R; Fleming, L; Shaw, DE; Bakke, PS; Caruso, M; Dahlen, SE; Fowler, SJ; Hashimoto, S; Horváth, I; Howarth, P; Krug, N; Montuschi, P; Sanak, M; Sandström, T; Singer, F; Sun, K; Pandis, I; Auffray, C; Sousa, AR; Adcock, IM; Chung, KF; Sterk, PJ; Djukanović, R; Skipp, PJ; The, U-Biopred, Study, Group Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome.
J Proteome Res. 2018; 17(6):2072-2091 Doi: 10.1021/acs.jproteome.8b00018
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Contreras-Duarte, S; Santander, N; Birner-Gruenberger, R; Wadsack, C; Rigotti, A; Busso, D High density lipoprotein cholesterol and proteome in SR-B1 KO mice: lost in precipitation.
J Transl Med. 2018; 16(1): 309-309. Doi: 10.1186/s12967-018-1683-4 [OPEN ACCESS]
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Fuchs, R; Stracke, A; Holzmann, V; Luschin-Ebengreuth, G; Meier-Allard, N; Ebner, N; Lassacher, TM; Absenger-Novak, M; Fröhlich, E; Schittmayer, M; Cano Crespo, S; Palacin, M; Rinner, B; Birner-Gruenberger, R Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc.
Biochim Biophys Acta Mol Cell Res. 2018; 1865(9):1211-1229 Doi: 10.1016/j.bbamcr.2018.06.006 [OPEN ACCESS]
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Rodríguez-Blanco, G; Zeneyedpour, L; Duijvesz, D; Hoogland, AM; Verhoef, EI; Kweldam, CF; Burgers, PC; Smitt, PS; Bangma, CH; Jenster, G; van, Leenders, GJLH; Dekker, LJM; Luider, TM Tissue proteomics outlines AGR2 AND LOX5 as markers for biochemical recurrence of prostate cancer.
Oncotarget. 2018; 9(92): 36444-36456. Doi: 10.18632/oncotarget.26342 [OPEN ACCESS]
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Tomin, T; Fritz, K; Gindlhuber, J; Waldherr, L; Pucher, B; Thallinger, GG; Nomura, DK; Schittmayer, M; Birner-Gruenberger, R Deletion of Adipose Triglyceride Lipase Links Triacylglycerol Accumulation to a More-Aggressive Phenotype in A549 Lung Carcinoma Cells.
J Proteome Res. 2018; 17(4):1415-1425 Doi: 10.1021/acs.jproteome.7b00782
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Vahdati Hassani, F; Abnous, K; Mehri, S; Jafarian, A; Birner-Gruenberger, R; Yazdian Robati, R; Hosseinzadeh, H Proteomics and phosphoproteomics analysis of liver in male rats exposed to bisphenol A: Mechanism of hepatotoxicity and biomarker discovery.
Food Chem Toxicol. 2018; 112(3):26-38 Doi: 10.1016/j.fct.2017.12.021
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Wolf, A; Liesinger, L; Spoerk, S; Schittmayer, M; Lang-Loidolt, D; Birner-Gruenberger, R; Tomazic, PV Olfactory cleft proteome does not reflect olfactory performance in patients with idiopathic and postinfectious olfactory disorder: A pilot study.
Sci Rep. 2018; 8(1):17554-17554 Doi: 10.1038/s41598-018-35776-8 [OPEN ACCESS]
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Wolff, D; Greinix, H; Lee, SJ; Gooley, T; Paczesny, S; Pavletic, S; Hakim, F; Malard, F; Jagasia, M; Lawitschka, A; Hansen, JA; Pulanic, D; Holler, E; Dickinson, A; Weissinger, E; Edinger, M; Sarantopoulos, S; Schultz, KR Biomarkers in chronic graft-versus-host disease: quo vadis?
Bone Marrow Transplant. 2018; 53(7):832-837 Doi: 10.1038/s41409-018-0092-x [OPEN ACCESS]
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2017

Fröhlich, E Role of omics techniques in the toxicity testing of nanoparticles.
J Nanobiotechnology. 2017; 15(1):84-84 Doi: 10.1186/s12951-017-0320-3 [OPEN ACCESS]
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Karbiener, M; Darnhofer, B; Frisch, MT; Rinner, B; Birner-Gruenberger, R; Gugatschka, M Comparative proteomics of paired vocal fold and oral mucosa fibroblasts.
J Proteomics. 2017; 155(6):11-21 Doi: 10.1016/j.jprot.2017.01.010 [OPEN ACCESS]
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