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Search Items: NITRIC OXIDE - METABOLISM , . hits: 94

2022

Koser, F; Hobbach, AJ; Abdellatif, M; Herbst, V; Türk, C; Reinecke, H; Krüger, M; Sedej, S; Linke, WA Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment.
Life Sci. 2022; 309:120998 Doi: 10.1016/j.lfs.2022.120998
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Pandey, AK; Waldeck-Weiermair, M; Wells, QS; Xiao, W; Yadav, S; Eroglu, E; Michel, T; Loscalzo, J Expression of CD70 Modulates Nitric Oxide and Redox Status in Endothelial Cells.
Arterioscler Thromb Vasc Biol. 2022; 42(9): 1169-1185. Doi: 10.1161/ATVBAHA.122.317866 [OPEN ACCESS]
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Sevimli, G; Smith, MJ; Caglar, TA; Bilir, Ş; Secilmis, M; Altun, HY; Yigit, EN; Yang, F; Keeley, TP; Malli, R; Öztürk, G; Mann, GE; Eroglu, E Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels.
Redox Biol. 2022; 53: 102319 Doi: 10.1016/j.redox.2022.102319 [OPEN ACCESS]
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2021

Hansmann, G; Sallmon, H; Roehr, CC; Kourembanas, S; Austin, ED; Koestenberger, M, , European, Pediatric, Pulmonary, Vascular, Disease, Network, (EPPVDN) Pulmonary hypertension in bronchopulmonary dysplasia.
Pediatr Res. 2021; 89(3):446-455 Doi: 10.1038/s41390-020-0993-4 [OPEN ACCESS]
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2020

Fielding, SS; Pijnenburg, M; de Jongste, J; Pike, K; Roberts, G; Petsky, H; Chang, AB; Fritsch, M; Frischer, T; Szefler, SJ; Gergen, P; Vermeulen, F; Vael, R; Turner, SS Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma?
Eur Respir J. 2020; 55(5): Doi: 10.1183/13993003.01879-2019
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2019

Eroglu, E; Saravi, SSS; Sorrentino, A; Steinhorn, B; Michel, T Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods.
Proc Natl Acad Sci U S A. 2019; 116(40):20210-20217 Doi: 10.1073/pnas.1910942116 [OPEN ACCESS]
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2018

Katanić, J; Pferschy-Wenzig, EM; Mihailović, V; Boroja, T; Pan, SP; Nikles, S; Kretschmer, N; Rosić, G; Selaković, D; Joksimović, J; Bauer, R Phytochemical analysis and anti-inflammatory effects of Filipendula vulgaris Moench extracts.
Food Chem Toxicol. 2018; 122(11):151-162 Doi: 10.1016/j.fct.2018.10.001
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Takahashi, K; Pavlidis, S; Ng, Kee, Kwong, F; Hoda, U; Rossios, C; Sun, K; Loza, M; Baribaud, F; Chanez, P; Fowler, SJ; Horvath, I; Montuschi, P; Singer, F; Musial, J; Dahlen, B; Dahlen, SE; Krug, N; Sandstrom, T; Shaw, DE; Lutter, R; Bakke, P; Fleming, LJ; Howarth, PH; Caruso, M; Sousa, AR; Corfield, J; Auffray, C; De, Meulder, B; Lefaudeux, D; Djukanovic, R; Sterk, PJ; Guo, Y; Adcock, IM; Chung, KF, , , on, behalf, of, the, U-BIOPRED, study, group Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.
Eur Respir J. 2018; 51(5): Doi: 10.1183/13993003.02173-2017
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2017

Charoensin, S; Eroglu, E; Opelt, M; Bischof, H; Madreiter-Sokolowski, CT; Kirsch, A; Depaoli, MR; Frank, S; Schrammel, A; Mayer, B; Waldeck-Weiermair, M; Graier, WF; Malli, R Intact mitochondrial Ca²⁺ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).
Free Radic Biol Med. 2017; 102(1):248-259 Doi: 10.1016/j.freeradbiomed.2016.11.049 [OPEN ACCESS]
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Eroglu, E; Rost, R; Bischof, H; Blass, S; Schreilechner, A; Gottschalk, B; Depaoli, MR; Klec, C; Charoensin, S; Madreiter-Sokolowski, CT; Ramadani, J; Waldeck-Weiermair, M; Graier, WF; Malli, R Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells.
J Vis Exp. 2017; 5(121): Doi: 10.3791/55486 [OPEN ACCESS]
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Parakaw, T; Suknuntha, K; Vivithanaporn, P; Schlagenhauf, A; Topanurak, S; Fucharoen, S; Pattanapanyasat, K; Schechter, A; Sibmooh, N; Srihirun, S Platelet inhibition and increased phosphorylated vasodilator-stimulated phosphoprotein following sodium nitrite inhalation.
Nitric Oxide. 2017; 66(6):10-16 Doi: 10.1016/j.niox.2017.02.008
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Rungatscher, A; Milani, E; Covajes, C; Hallström, S; Gottin, L; Guidi, GC; Luciani, GB; Faggian, G Blood transfusions may impair endothelium-dependent vasodilatation during coronary artery bypass surgery.
Microvasc Res. 2017; 112(1):109-114 Doi: 10.1016/j.mvr.2017.04.001
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Steinbacher, M; Pfleger, A; Schwantzer, G; Jauk, S; Weinhandl, E; Eber, E Small airway function before and after cold dry air challenge in pediatric asthma patients during remission.
Pediatr Pulmonol. 2017; 52(7):873-879 Doi: 10.1002/ppul.23724
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Üçal, M; Kraitsy, K; Weidinger, A; Paier-Pourani, J; Patz, S; Fink, B; Molcanyi, M; Schäfer, U Comprehensive Profiling of Modulation of Nitric Oxide Levels and Mitochondrial Activity in the Injured Brain: An Experimental Study Based on the Fluid Percussion Injury Model in Rats.
J Neurotrauma. 2017; 34(2):475-486 Doi: 10.1089/neu.2016.4411
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2016

Alesutan, I; Feger, M; Tuffaha, R; Castor, T; Musculus, K; Buehling, SS; Heine, CL; Kuro-O, M; Pieske, B; Schmidt, K; Tomaschitz, A; Maerz, W; Pilz, S; Meinitzer, A; Voelkl, J; Lang, F Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.
Cardiovasc Res. 2016; 110(3):408-418 Doi: 10.1093/cvr/cvw062 [OPEN ACCESS]
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Eroglu, E; Gottschalk, B; Charoensin, S; Blass, S; Bischof, H; Rost, R; Madreiter-Sokolowski, CT; Pelzmann, B; Bernhart, E; Sattler, W; Hallström, S; Malinski, T; Waldeck-Weiermair, M; Graier, WF; Malli, R Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics.
Nat Commun. 2016; 7(3):10623-10623 Doi: 10.1038/ncomms10623 [OPEN ACCESS]
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Opelt, M; Eroglu, E; Waldeck-Weiermair, M; Russwurm, M; Koesling, D; Malli, R; Graier, WF; Fassett, JT; Schrammel, A; Mayer, B Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.
J Biol Chem. 2016; 291(46):24076-24084 Doi: 10.1074/jbc.M116.752071 [OPEN ACCESS]
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2015

Baranyi, A; Amouzadeh-Ghadikolai, O; Rothenhäusler, HB; Theokas, S; Robier, C; Baranyi, M; Koppitz, M; Reicht, G; Hlade, P; Meinitzer, A Nitric Oxide-Related Biological Pathways in Patients with Major Depression.
PLoS One. 2015; 10(11):e0143397-e0143397 Doi: 10.1371/journal.pone.0143397 [OPEN ACCESS]
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Lee, DI; Zhu, G; Sasaki, T; Cho, GS; Hamdani, N; Holewinski, R; Jo, SH; Danner, T; Zhang, M; Rainer, PP; Bedja, D; Kirk, JA; Ranek, MJ; Dostmann, WR; Kwon, C; Margulies, KB; Van Eyk, JE; Paulus, WJ; Takimoto, E; Kass, DA Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.
Nature. 2015; 519(7544):472-476 Doi: 10.1038/nature14332 [OPEN ACCESS]
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Olschewski, A; Weir, EK Redox regulation of ion channels in the pulmonary circulation.
Antioxid Redox Signal. 2015; 22(6):465-485 Doi: 10.1089/ars.2014.5899 [OPEN ACCESS]
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2014

Aguilera, V; Briceño, L; Contreras, H; Lamperti, L; Sepúlveda, E; Díaz-Perez, F; León, M; Veas, C; Maura, R; Toledo, JR; Fernández, P; Covarrubias, A; Zuñiga, FA; Radojkovic, C; Escudero, C; Aguayo, C Endothelium trans differentiated from Wharton's jelly mesenchymal cells promote tissue regeneration: potential role of soluble pro-angiogenic factors.
PLoS One. 2014; 9(11):e111025-e111025 Doi: 10.1371/journal.pone.0111025 [OPEN ACCESS]
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Hofmann, A; Gosemann, JH; Takahashi, T; Friedmacher, F; Duess, JW; Puri, P Imbalance of caveolin-1 and eNOS expression in the pulmonary vasculature of experimental diaphragmatic hernia.
Birth Defects Res B Dev Reprod Toxicol. 2014; 101(4):341-346 Doi: 10.1002/bdrb.21117
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Kozina, A; Opresnik, S; Wong, MS; Hallström, S; Graier, WF; Malli, R; Schröder, K; Schmidt, K; Frank, S Oleoyl-lysophosphatidylcholine limits endothelial nitric oxide bioavailability by induction of reactive oxygen species.
PLoS One. 2014; 9(11):e113443-e113443 Doi: 10.1371/journal.pone.0113443 [OPEN ACCESS]
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Nematollahi-Mahani, SN; Azizollahi, GH; Baneshi, MR; Safari, Z; Azizollahi, S Effect of folic acid and zinc sulphate on endocrine parameters and seminal antioxidant level after varicocelectomy.
Andrologia. 2014; 46(3): 240-245. Doi: 10.1111/and.12067 [OPEN ACCESS]
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Pilz, S; Edelmann, F; Meinitzer, A; Gelbrich, G; Döner, U; Düngen, HD; Tomaschitz, A; Kienreich, K; Gaksch, M; Duvinage, A; Stahrenberg, R; Kunde, J; Schmidt, A; März, W; Wachter, R; Pieske, B Associations of methylarginines and homoarginine with diastolic dysfunction and cardiovascular risk factors in patients with preserved left ventricular ejection fraction.
J Card Fail. 2014; 20(12):923-30 Doi: 10.1016/j.cardfail.2014.09.004
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Sikiric, P; Seiwerth, S; Rucman, R; Turkovic, B; Rokotov, DS; Brcic, L; Sever, M; Klicek, R; Radic, B; Drmic, D; Ilic, S; Kolenc, D; Aralica, G; Stupnisek, M; Suran, J; Barisic, I; Dzidic, S; Vrcic, H; Sebecic, B Stable gastric pentadecapeptide BPC 157-NO-system relation.
Curr Pharm Des. 2014; 20(7): 1126-1135. Doi: 10.2174/13816128113190990411
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2013

Erdmann, J; Stark, K; Esslinger, UB; Rumpf, PM; Koesling, D; de Wit, C; Kaiser, FJ; Braunholz, D; Medack, A; Fischer, M; Zimmermann, ME; Tennstedt, S; Graf, E; Eck, S; Aherrahrou, Z; Nahrstaedt, J; Willenborg, C; Bruse, P; Brænne, I; Nöthen, MM; Hofmann, P; Braund, PS; Mergia, E; Reinhard, W; Burgdorf, C; Schreiber, S; Balmforth, AJ; Hall, AS; Bertram, L; Steinhagen-Thiessen, E; Li, SC; März, W; Reilly, M; Kathiresan, S; McPherson, R; Walter, U; CARDIoGRAM; Ott, J; Samani, NJ; Strom, TM; Meitinger, T; Hengstenberg, C; Schunkert, H Dysfunctional nitric oxide signalling increases risk of myocardial infarction.
Nature. 2013; 504(7480):432-436 Doi: 10.1038/nature12722
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Paneni, F; Osto, E; Costantino, S; Mateescu, B; Briand, S; Coppolino, G; Perna, E; Mocharla, P; Akhmedov, A; Kubant, R; Rohrer, L; Malinski, T; Camici, GG; Matter, CM; Mechta-Grigoriou, F; Volpe, M; Lüscher, TF; Cosentino, F Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction.
Circulation. 2013; 127(11):1229-40, e1-21 Doi: 10.1161/CIRCULATIONAHA.112.000826
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2011

Breitbach, K; Wongprompitak, P; Steinmetz, I Distinct roles for nitric oxide in resistant C57BL/6 and susceptible BALB/c mice to control Burkholderia pseudomallei infection.
BMC Immunol. 2011; 12(6):20-20 Doi: 10.1186/1471-2172-12-20 [OPEN ACCESS]
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Sourij, H; Meinitzer, A; Pilz, S; Grammer, TB; Winkelmann, BR; Boehm, BO; März, W Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography.
Atherosclerosis. 2011; 218(1):220-225 Doi: 10.1016/j.atherosclerosis.2011.04.041 [OPEN ACCESS]
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2010

Darra, E; Rungatscher, A; Carcereri de Prati, A; Podesser, BK; Faggian, G; Scarabelli, T; Mazzucco, A; Hallström, S; Suzuki, H Dual modulation of nitric oxide production in the heart during ischaemia/reperfusion injury and inflammation.
Thromb Haemost. 2010; 104(2): 200-206. Doi: 10.1160/TH09-08-0554 [OPEN ACCESS]
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Egemnazarov, B; Schermuly, RT; Dahal, BK; Elliott, GT; Hoglen, NC; Surber, MW; Weissmann, N; Grimminger, F; Seeger, W; Ghofrani, HA Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction.
Respir Res. 2010; 11(11):81-81 Doi: 10.1186/1465-9921-11-81 [OPEN ACCESS]
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Gruber, HJ; Bernecker, C; Pailer, S; Fauler, G; Horejsi, R; Möller, R; Lechner, A; Fazekas, F; Truschnig-Wilders, M Hyperinsulinaemia in migraineurs is associated with nitric oxide stress.
Cephalalgia. 2010; 30(5): 593-598. Doi: 10.1111/j.1468-2982.2009.02012.x
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Osto, E; Tona, F; De, Bon, E; Iliceto, S; Cella, G Endothelial dysfunction in cardiac allograft vasculopathy: potential pharmacological interventions.
Curr Vasc Pharmacol. 2010; 8(2):169-88 Doi: 10.2174/157016110790886992
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Schmidt, K; Martens-Lobenhoffer, J; Meinitzer, A; Graier, WF; Torres, CM; Venema, RC; Mayer, B Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formation.
Nitric Oxide. 2010; 22(4): 281-289. Doi: 10.1016/j.niox.2010.02.001 [OPEN ACCESS]
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Siamwala, JH; Majumder, S; Tamilarasan, KP; Muley, A; Reddy, SH; Kolluru, GK; Sinha, S; Chatterjee, S Simulated microgravity promotes nitric oxide-supported angiogenesis via the iNOS-cGMP-PKG pathway in macrovascular endothelial cells.
FEBS Lett. 2010; 584(15): 3415-3423. Doi: 10.1016/j.febslet.2010.06.039 [OPEN ACCESS]
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2009

Balenovic, D; Bencic, ML; Udovicic, M; Simonji, K; Hanzevacki, JS; Barisic, I; Kranjcevic, S; Prkacin, I; Coric, V; Brcic, L; Coric, M; Brcic, I; Borovic, S; Radic, B; Drmic, D; Vrcic, H; Seiwerth, S; Sikiric, P Inhibition of methyldigoxin-induced arrhythmias by pentadecapeptide BPC 157: a relation with NO-system.
Regul Pept. 2009; 156(1-3): 83-89. Doi: 10.1016/j.regpep.2009.05.008
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Deng, S; Kruger, A; Schmidt, A; Metzger, A; Yan, T; Gödtel-Armbrust, U; Hasenfuss, G; Brunner, F; Wojnowski, L Differential roles of nitric oxide synthase isozymes in cardiotoxicity and mortality following chronic doxorubicin treatment in mice.
Naunyn Schmiedebergs Arch Pharmacol. 2009; 380(1): 25-34. Doi: 10.1007/s00210-009-0407-y [OPEN ACCESS]
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Donnerer, J; Liebmann, I; Schuligoi, R Capsaicin- and mustard oil-induced extracellular signal-regulated protein kinase phosphorylation in sensory neurons in vivo: effects of neurokinins 1 and 2 receptor antagonists and of a nitric oxide synthase inhibitor.
Basic Clin Pharmacol Toxicol. 2009; 104(1):11-16 Doi: 10.1111/j.1742-7843.2008.00338.x [OPEN ACCESS]
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Egemnazarov, B; Sydykov, A; Schermuly, RT; Weissmann, N; Stasch, JP; Sarybaev, AS; Seeger, W; Grimminger, F; Ghofrani, HA Novel soluble guanylyl cyclase stimulator BAY 41-2272 attenuates ischemia-reperfusion-induced lung injury.
Am J Physiol Lung Cell Mol Physiol. 2009; 296(3):L462-L469 Doi: 10.1152/ajplung.90377.2008
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Kawano, T; Zoga, V; Kimura, M; Liang, MY; Wu, HE; Gemes, G; McCallum, JB; Kwok, WM; Hogan, QH; Sarantopoulos, CD Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation.
Mol Pain. 2009; 5(21): 12-12. Doi: 10.1186/1744-8069-5-12 [OPEN ACCESS]
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Ketabchi, F; Egemnazarov, B; Schermuly, RT; Ghofrani, HA; Seeger, W; Grimminger, F; Shid-Moosavi, M; Dehghani, GA; Weissmann, N; Sommer, N Effects of hypercapnia with and without acidosis on hypoxic pulmonary vasoconstriction.
Am J Physiol Lung Cell Mol Physiol. 2009; 297(5):L977-L983 Doi: 10.1152/ajplung.00074.2009
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Majumder, S; Rajaram, M; Muley, A; Reddy, HS; Tamilarasan, KP; Kolluru, GK; Sinha, S; Siamwala, JH; Gupta, R; Ilavarasan, R; Venkataraman, S; Sivakumar, KC; Anishetty, S; Kumar, PG; Chatterjee, S Thalidomide attenuates nitric oxide-driven angiogenesis by interacting with soluble guanylyl cyclase.
Br J Pharmacol. 2009; 158(7): 1720-1734. Doi: 10.1111/j.1476-5381.2009.00446.x [OPEN ACCESS]
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2008

Delli, Gatti, C; Osto, E; Kouroedov, A; Eto, M; Shaw, S; Volpe, M; Lüscher, TF; Cosentino, F Pulsatile stretch induces release of angiotensin II and oxidative stress in human endothelial cells: effects of ACE inhibition and AT1 receptor antagonism.
Clin Exp Hypertens. 2008; 30(7):616-27 Doi: 10.1080/10641960802443183
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Majumder, S; Muley, A; Kolluru, GK; Saurabh, S; Tamilarasan, KP; Chandrasekhar, S; Reddy, HB; Purohit, S; Chatterjee, S Cadmium reduces nitric oxide production by impairing phosphorylation of endothelial nitric oxide synthase.
Biochem Cell Biol. 2008; 86(1):1-10 Doi: 10.1139/o07-146
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Osto, E; Matter, CM; Kouroedov, A; Malinski, T; Bachschmid, M; Camici, GG; Kilic, U; Stallmach, T; Boren, J; Iliceto, S; Lüscher, TF; Cosentino, F c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress.
Circulation. 2008; 118(20):2073-80 Doi: 10.1161/CIRCULATIONAHA.108.765032
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Siekmeier, R; Grammer, T; März, W Roles of oxidants, nitric oxide, and asymmetric dimethylarginine in endothelial function.
J Cardiovasc Pharmacol Ther. 2008; 13(4):279-297 Doi: 10.1177/1074248408326488
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2007

Anaid Shahbazian; Petkov, V; Baykuscheva-Gentscheva, T; Hoeger, H; Painsipp, E; Holzer, P; Mosgoeller, W Involvement of endothelial NO in the dilator effect of VIP on rat isolated pulmonary artery.
Regul Pept. 2007; 139(1-3): 102-108. Doi: 10.1016/j.regpep.2006.10.012
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Horak, F; Moeller, A; Singer, F; Straub, D; Höller, B; Helbich, TH; Schneider, B; Eichler, I; Wildhaber, JH; Hall, GL Longitudinal monitoring of pediatric cystic fibrosis lung disease using nitrite in exhaled breath condensate.
Pediatr Pulmonol. 2007; 42(12):1198-206 Doi: 10.1002/ppul.20719
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Osto, E; Coppolino, G; Volpe, M; Cosentino, F Restoring the dysfunctional endothelium.
Curr Pharm Des. 2007; 13(10):1053-68 Doi: 10.2174/138161207780487566
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