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Search Items: MUSCLE, SMOOTH, VASCULAR - DRUG EFFECTS , . hits: 55

2017

Wu, BJ; Li, Y; Ong, KL; Sun, Y; Shrestha, S; Hou, L; Johns, D; Barter, PJ; Rye, KA Reduction of In-Stent Restenosis by Cholesteryl Ester Transfer Protein Inhibition.
ARTERIOSCL THROM VAS. 2017; 37(12): 2333-2341. [OPEN ACCESS]
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2016

Alesutan, I; Feger, M; Tuffaha, R; Castor, T; Musculus, K; Buehling, SS; Heine, CL; Kuro-O, M; Pieske, B; Schmidt, K; Tomaschitz, A; Maerz, W; Pilz, S; Meinitzer, A; Voelkl, J; Lang, F Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.
Cardiovasc Res. 2016; 110(3):408-418 [OPEN ACCESS]
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Dellera, F; Ganzetti, GS; Froio, A; Manzini, S; Busnelli, M; Meinitzer, A; Sirtori, CR; Chiesa, G; Parolini, C L-homoarginine administration reduces neointimal hyperplasia in balloon-injured rat carotids.
Thromb Haemost. 2016; 116(2):400-402 [OPEN ACCESS]
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2014

Biasin, V; Chwalek, K; Wilhelm, J; Best, J; Marsh, LM; Ghanim, B; Klepetko, W; Fink, L; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
Int J Biochem Cell Biol. 2014; 54(3):137-148
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Veith, C; Zakrzewicz, D; Dahal, BK; Bálint, Z; Murmann, K; Wygrecka, M; Seeger, W; Schermuly, RT; Weissmann, N; Kwapiszewska, G Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.
Thromb Haemost. 2014; 112(6):1288-1303
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Weisel, FC; Kloepping, C; Pichl, A; Sydykov, A; Kojonazarov, B; Wilhelm, J; Roth, M; Ridge, KM; Igarashi, K; Nishimura, K; Maison, W; Wackendorff, C; Klepetko, W; Jaksch, P; Ghofrani, HA; Grimminger, F; Seeger, W; Schermuly, RT; Weissmann, N; Kwapiszewska, G Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling.
Circulation. 2014; 129(14):1510-1523 [OPEN ACCESS]
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2013

Bondarenko, AI; Drachuk, K; Panasiuk, O; Sagach, V; Deak, AT; Malli, R; Graier, WF N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs.
Br J Pharmacol. 2013; 169(4):933-948 [OPEN ACCESS]
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König, S; Browne, S; Doleschal, B; Schernthaner, M; Poteser, M; Mächler, H; Wittchow, E; Braune, M; Muik, M; Romanin, C; Groschner, K Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.
Am J Physiol Heart Circ Physiol. 2013; 305(11):H1646-H1657 [OPEN ACCESS]
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Stulnig, G; Frisch, MT; Crnkovic, S; Stiegler, P; Sereinigg, M; Stacher, E; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid (DHA)-induced heme oxygenase-1 attenuates cytotoxic effects of DHA in vascular smooth muscle cells.
Atherosclerosis. 2013; 230(2):406-413
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2012

Crnkovic, S; Riederer, M; Lechleitner, M; Hallström, S; Malli, R; Graier, WF; Lindenmann, J; Popper, H; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca²⁺-dependent induction of oxidative stress.
Free Radic Biol Med. 2012; 52(9):1786-1795 [OPEN ACCESS]
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Kwapiszewska, G; Markart, P; Dahal, BK; Kojonazarov, B; Marsh, LM; Schermuly, RT; Taube, C; Meinhardt, A; Ghofrani, HA; Steinhoff, M; Seeger, W; Preissner, KT; Olschewski, A; Weissmann, N; Wygrecka, M PAR-2 inhibition reverses experimental pulmonary hypertension.
Circ Res. 2012; 110(9):1179-1191 [OPEN ACCESS]
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Li, Y; Connolly, M; Nagaraj, C; Tang, B; Bálint, Z; Popper, H; Smolle-Juettner, FM; Lindenmann, J; Kwapiszewska, G; Aaronson, PI; Wohlkoenig, C; Leithner, K; Olschewski, H; Olschewski, A Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation.
Am J Respir Cell Mol Biol. 2012; 46(3):372-379
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2011

Olschewski, A Blocking potassium channels: a new principle for treating restenosis?
Cardiovasc Res. 2011; 89(2):255-257 [OPEN ACCESS]
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2010

Baulmann, J; Nürnberger, J; Slany, J; Schmieder, R; Schmidt-Trucksäss, A; Baumgart, D; Cremerius, P; Hess, O; Mortensen, K; Weber, T Arterial stiffness and pulse wave analysis].
Dtsch Med Wochenschr. 2010; 135 Suppl 1(8):S4-14
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Nikam, VS; Schermuly, RT; Dumitrascu, R; Weissmann, N; Kwapiszewska, G; Morrell, N; Klepetko, W; Fink, L; Seeger, W; Voswinckel, R Treprostinil inhibits the recruitment of bone marrow-derived circulating fibrocytes in chronic hypoxic pulmonary hypertension.
Eur Respir J. 2010; 36(6):1302-1314 [OPEN ACCESS]
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2008

Hajos, F; Stark, B; Hensler, S; Prassl, R; Mosgoeller, W Inhalable liposomal formulation for vasoactive intestinal peptide
Int J Pharm. 2008; 357(1-2):286-294
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2007

Anaid Shahbazian; Petkov, V; Baykuscheva-Gentscheva, T; Hoeger, H; Painsipp, E; Holzer, P; Mosgoeller, W Involvement of endothelial NO in the dilator effect of VIP on rat isolated pulmonary artery.
Regul Pept. 2007; 139(1-3): 102-108.
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2006

Isoda, K; Young, JL; Zirlik, A; MacFarlane, LA; Tsuboi, N; Gerdes, N; Schönbeck, U; Libby, P Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.
ARTERIOSCL THROM VAS. 2006; 26(3): 611-617. [OPEN ACCESS]
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Wakabayashi, I; Poteser, M; Groschner, K Intracellular pH as a determinant of vascular smooth muscle function.
J Vasc Res. 2006; 43(3):238-250 [OPEN ACCESS]
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2005

Stolle, K; Schnoor, M; Fuellen, G; Spitzer, M; Engel, T; Spener, F; Cullen, P; Lorkowski, S Cloning, cellular localization, genomic organization, and tissue-specific expression of the TGFbeta1-inducible SMAP-5 gene.
Gene. 2005; 351(6-7):119-130
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2004

Bondarenko, A Sodium-calcium exchanger contributes to membrane hyperpolarization of intact endothelial cells from rat aorta during acetylcholine stimulation.
Br J Pharmacol. 2004; 143(1):9-18 [OPEN ACCESS]
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2003

Poteser, M; Wakabayashi, I; Rosker, C; Teubl, M; Schindl, R; Soldatov, NM; Romanin, C; Groschner, K Crosstalk between voltage-independent Ca2+ channels and L-type Ca2+ channels in A7r5 vascular smooth muscle cells at elevated intracellular pH: evidence for functional coupling between L-type Ca2+ channels and a 2-APB-sensitive cation channel.
Circ Res. 2003; 92(8):888-896 [OPEN ACCESS]
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Wakabayashi, I; Groschner, K Vascular actions of anthracycline antibiotics.
Curr Med Chem. 2003; 10(5):427-436
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2002

Juránek, I; Bauer, V; Donnerer, J; Lembeck, F; Peskar, BA Severe hypoxia inhibits prostaglandin I(2) biosynthesis and vasodilatory responses induced by ionophore A23187 in the isolated rabbit ear.
Pharmacology. 2002; 66(4):199-205
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Olschewski, A; Hong, Z; Linden, BC; Porter, VA; Weir, EK; Cornfield, DN Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model.
AMER J PHYSIOL-LUNG CELL M PH 2002 283: L1103-L1109. [OPEN ACCESS]
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Olschewski, A; Hong, Z; Nelson, DP; Weir, EK Graded response of K+ current, membrane potential, and Ca2+i to hypoxia in pulmonary arterial smooth muscle.
AMER J PHYSIOL-LUNG CELL M PH 2002 283: L1143-L1150. [OPEN ACCESS]
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Schuller-Petrovic, S; Stessel, H; Brunner, F Ca2+ mobilization in saphenous vein smooth muscle cells derived from patients with primary varicosity.
Eur J Clin Invest. 2002; 32(9):649-656
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2001

Wakabayashi, I; Masui, H; Groschner, K Intracellular alkalinization augments alpha(1)-adrenoceptor-mediated vasoconstriction by promotion of Ca(2+) entry through the non-L-type Ca(2+) channels.
Eur J Pharmacol. 2001; 428(2):251-259
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2000

Wakabayashi, I; Mayer, B; Groschner, K Inhibitory effects of aclarubicin on nitric oxide production in aortic smooth muscle cells and macrophages.
Biochem Pharmacol. 2000; 59(6):719-726
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1999

Fleischhacker, E; Esenabhalu, VE; Spitaler, M; Holzmann, S; Skrabal, F; Koidl, B; Kostner, GM; Graier, WF Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution.
Diabetes. 1999; 48(6):1323-1330 [OPEN ACCESS]
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Graier, WF; Posch, K; Fleischhacker, E; Wascher, TC; Kostner, GM Increased superoxide anion formation in endothelial cells during hyperglycemia: an adaptive response or initial step of vascular dysfunction?
Diabetes Res Clin Pract. 1999; 45(2-3):153-160
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Köppel, H; Holzmann, S; Pilger, E; Klein, W; Gasser, R Minimal effects of levosimendan on coronary artery smooth muscle tone.
CARDIOVASC DRUG THER 1999 13: 357-358.
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1998

Sinzinger, H; Wasinger, T; Böck, P; O'Grady, J; Peskar, BA Alteration of rat cerebral microvascular eicosanoid formation by isradipine, a calcium channel blocker.
Prostaglandins Leukot Essent Fatty Acids. 1998; 58(1):1-7
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Wachter, CH; Heinemann, A; Donnerer, J; Pabst, MA; Holzer, P Mediation by 5_hydroxytryptamine of the femoral vasoconstriction induced by acid challenge of the rat gastric mucosa.
J PHYSIOL, LONDON 1998 509: 541-550. [OPEN ACCESS]
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1997

Gasser, R; Grisold, M; Pokan, R; Horn, E; Horn, S; Pettnehazy, T; Scheidl, S; Klein, W Blockade of ATP-dependent K+ channels in myocardium and coronary artery smooth muscle: a possible cause of increased cardiovascular mortality in sulfonylurea-treated patients.
CARDIOVASC DRUG THER 1997 11: 87-89.
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Heinemann, A; Wachter, CH; Holzer, P; Fickert, P; Stauber, RE Nitric oxide-dependent and -independent vascular hyporeactivity in mesenteric arteries of portal hypertensive rats.
Br J Pharmacol. 1997; 121(5):1031-1037 [OPEN ACCESS]
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Schuhmann, K; Romanin, C; Baumgartner, W; Groschner, K Intracellular Ca2+ inhibits smooth muscle L-type Ca2+ channels by activation of protein phosphatase type 2B and by direct interaction with the channel.
J Gen Physiol. 1997; 110(5):503-513 [OPEN ACCESS]
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1996

Köppel, H; Gasser, R; Klein, W; Holzmann, S ACE inhibitors with SH groups have no effect of ATP-dependent K channels--a dissertation
Acta Med Austriaca. 1996; 23(3):109-112
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1995

Klein, W; Eber, B; Dusleag, J; Gasser, R; Fruhwald, FM; Schumacher, M; Zweiker, R; Stoschitzky, K Hypertension and hemorheology
Wien Med Wochenschr. 1995; 145(15-16):355-357
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Patacchini, R; Barthò, L; Holzer, P; Maggi, CA Activity of SR 142801 at peripheral tachykinin receptors.
Eur J Pharmacol. 1995; 278(1):17-25
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Rodrigues, M; Sinzinger, H; Kritz, H; Peskar, BA; O'Grady, J; Rogatti, W PGE0 inhibits collagen and glycosaminoglycan-synthesis in the rabbit arterial wall.
Vasa. 1995; 24(4):333-336
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Sutter, B; Suzuki, S; Kassell, NF; Lee, KS Characteristics of relaxation induced by calcitonin gene-related peptide in contracted rabbit basilar artery.
J Neurosurg. 1995; 82(1):91-96
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1994

Herbert, MK; Holzer, P Interleukin-1 beta enhances capsaicin-induced neurogenic vasodilatation in the rat skin.
BRIT J PHARMACOL 1994 111: 681-686. [OPEN ACCESS]
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Holzmann, S; Kukovetz, WR; Windischhofer, W; Paschke, E; Graier, WF Pharmacologic differentiation between endothelium-dependent relaxations sensitive and resistant to nitro-L-arginine in coronary arteries.
J Cardiovasc Pharmacol. 1994; 23(5):747-756
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Schuhmann, K; Groschner, K Protein kinase-C mediates dual modulation of L-type Ca2+ channels in human vascular smooth muscle.
FEBS Lett. 1994; 341(2-3):208-212
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1993

Holzer, P; Lippe, IT; Jocic, M; Wachter, C; Erb, R; Heinemann, A Nitric oxide-dependent and -independent hyperaemia due to calcitonin gene-related peptide in the rat stomach.
Br J Pharmacol. 1993; 110(1):404-410 [OPEN ACCESS]
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Kühberger, E; Kukovetz, WR; Groschner, K Cromakalim inhibits multiple mechanisms of smooth muscle activation with similar stereoselectivity.
J Cardiovasc Pharmacol. 1993; 21(6):947-954
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1991

Pritze, S; Simmet, T; Peskar, BA Effect of platelet-activating factor on porcine pulmonary blood vessels in vitro.
Naunyn Schmiedebergs Arch Pharmacol. 1991; 344(4):495-499
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1990

Amann, R; Donnerer, J; Lembeck, F Activation of primary afferent neurons by thermal stimulation. Influence of ruthenium red.
Naunyn Schmiedebergs Arch Pharmacol. 1990; 341(1-2):108-113
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Gelband, CH; Silberberg, SD; Groschner, K; van Breemen, C ATP inhibits smooth muscle Ca2(+)-activated K+ channels.
Proc Biol Sci. 1990; 242(1303):23-28
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