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Search Items: MITOCHONDRIA, . hits: 369

2020

Bugger, H; Pfeil, K Mitochondrial ROS in myocardial ischemia reperfusion and remodeling
BBA-MOL BASIS DIS. 2020; 1866(7): 165768
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Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3): [OPEN ACCESS]
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Gollmer, J; Zirlik, A; Bugger, H Mitochondrial Mechanisms in Diabetic Cardiomyopathy
DIABETES METAB J. 2020; 44(1): 33-53. [OPEN ACCESS]
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Grubelnik, V; Markovic, R; Lipovsek, S; Leitinger, G; Gosak, M; Dolensek, J; Valladolid-Acebes, I; Berggren, PO; Stozer, A; Perc, M; Marhl, M Modelling of dysregulated glucagon secretion in type 2 diabetes by considering mitochondrial alterations in pancreatic alpha-cells
ROY SOC OPEN SCI. 2020; 7(1): 191171 [OPEN ACCESS]
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Gutiérrez, T; Qi, H; Yap, MC; Tahbaz, N; Milburn, LA; Lucchinetti, E; Lou, PH; Zaugg, M; LaPointe, PG; Mercier, P; Overduin, M; Bischof, H; Burgstaller, S; Malli, R; Ballanyi, K; Shuai, J; Simmen, T The ER chaperone calnexin controls mitochondrial positioning and respiration.
Sci Signal. 2020; 13(638):
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Kolleritsch, S; Kien, B; Schoiswohl, G; Diwoky, C; Schreiber, R; Heier, C; Maresch, LK; Schweiger, M; Eichmann, TO; Stryeck, S; Krenn, P; Tomin, T; Schittmayer, M; Kolb, D; Rülicke, T; Hoefler, G; Wolinski, H; Madl, T; Birner-Gruenberger, R; Haemmerle, G Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.
Cardiovasc Res. 2020; 116(2):339-352 [OPEN ACCESS]
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Mancuso, M; Arnold, M; Bersano, A; Burlina, A; Chabriat, H; Debette, S; Enzinger, C; Federico, A; Filla, A; Finsterer, J; Hunt, D; Lesnik Oberstein, S; Tournier-Lasserve, E; Markus, HS Monogenic cerebral small-vessel diseases: diagnosis and therapy. Consensus recommendations of the European Academy of Neurology.
Eur J Neurol. 2020;
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Moreau, R; Clària, J; Aguilar, F; Fenaille, F; Lozano, JJ; Junot, C; Colsch, B; Caraceni, P; Trebicka, J; Pavesi, M; Alessandria, C; Nevens, F; Saliba, F; Welzel, TM; Albillos, A; Gustot, T; Fernández, J; Moreno, C; Baldassarre, M; Zaccherini, G; Piano, S; Montagnese, S; Vargas, V; Genescà, J; Solà, E; Bernal, W; Butin, N; Hautbergue, T; Cholet, S; Castelli, F; Jansen, C; Steib, C; Campion, D; Mookerjee, R; Rodríguez-Gandía, M; Soriano, G; Durand, F; Benten, D; Bañares, R; Stauber, RE; Gronbaek, H; Coenraad, MJ; Ginès, P; Gerbes, A; Jalan, R; Bernardi, M; Arroyo, V; Angeli, P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair; European Foundation for the Study of Chronic Liver Failure (EF Clif) Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF.
J Hepatol. 2020; 72(4):688-701
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Špaková, I; Graier, WF; Rabajdová, M; Dubayová, K; Nagyová, V; Mareková, M Hypoxia factors suppression effect on the energy metabolism of a malignant melanoma cell SK-MEL-30.
Eur Rev Med Pharmacol Sci. 2020; 24(9): 4909-4920.
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Radulović, S; Gottschalk, B; Hörl, G; Zardoya-Laguardia, P; Schilcher, I; Hallström, S; Vujić, N; Schmidt, K; Trieb, M; Graier, WF; Malli, R; Kratky, D; Marsche, G; Frank, S Endothelial lipase increases eNOS activating capacity of high-density lipoprotein.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 158612-158612. [OPEN ACCESS]
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Smolle, E; Leko, P; Stacher-Priehse, E; Brcic, L; El-Heliebi, A; Hofmann, L; Quehenberger, F; Hrzenjak, A; Popper, HH; Olschewski, H; Leithner, K Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer.
Mol Oncol. 2020;
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Sommer, AP; Schemmer, P; Pavlath, AE; Forsterling, HD; Mester, AR; Trelles, MA Quantum biology in low level light therapy: death of a dogma
ANN TRANSL MED. 2020; 8(7): 440 [OPEN ACCESS]
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Wallner, M; Eaton, DM; Berretta, RM; Liesinger, L; Schittmayer, M; Gindlhuber, J; Wu, J; Jeong, MY; Lin, YH; Borghetti, G; Baker, ST; Zhao, H; Pfleger, J; Blass, S; Rainer, PP; von Lewinski, D; Bugger, H; Mohsin, S; Graier, WF; Zirlik, A; McKinsey, TA; Birner-Gruenberger, R; Wolfson, MR; Houser, SR HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Sci Transl Med. 2020; 12(525): [OPEN ACCESS]
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Weber, RA; Yen, FS; Nicholson, SPV; Alwaseem, H; Bayraktar, EC; Alam, M; Timson, RC; La, K; Abu-Remaileh, M; Molina, H; Birsoy, K Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.
Mol Cell. 2020; 77(3):645-655 [OPEN ACCESS]
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Weixler, V; Lapusca, R; Grangl, G; Guariento, A; Saeed, MY; Cowan, DB; Del Nido, PJ; McCully, JD; Friehs, I Autogenous mitochondria transplantation for treatment of right heart failure.
J Thorac Cardiovasc Surg. 2020;
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2019

Baracco, EE; Castoldi, F; Durand, S; Enot, DP; Tadic, J; Kainz, K; Madeo, F; Chery, A; Izzo, V; Maiuri, MC; Pietrocola, F; Kroemer, G α-Ketoglutarate inhibits autophagy.
Aging (Albany NY). 2019; 11(11):3418-3431 [OPEN ACCESS]
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Boonsawat, P; Joset, P; Steindl, K; Oneda, B; Gogoll, L; Azzarello-Burri, S; Sheth, F; Datar, C; Verma, IC; Puri, RD; Zollino, M; Bachmann-Gagescu, R; Niedrist, D; Papik, M; Figueiro-Silva, J; Masood, R; Zweier, M; Kraemer, D; Lincoln, S; Rodan, L; Undiagnosed Diseases Network (UDN); Passemard, S; Drunat, S; Verloes, A; Horn, AHC; Sticht, H; Steinfeld, R; Plecko, B; Latal, B; Jenni, O; Asadollahi, R; Rauch, A Elucidation of the phenotypic spectrum and genetic landscape in primary and secondary microcephaly.
GENET MED. 2019; 21(9): 2043-2058. [OPEN ACCESS]
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Farrugia, G; Azzopardi, M; Saliba, C; Grech, G; Gross, AS; Pistolic, J; Benes, V; Vassallo, N; Borg, J; Madeo, F; Eisenberg, T; Balzan, R Aspirin impairs acetyl-coenzyme A metabolism in redox-compromised yeast cells.
Sci Rep. 2019; 9(1):6152-6152 [OPEN ACCESS]
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Fissolo, N; Cervera-Carles, L; Villar Guimerans, LM; Lleó, A; Clarimón, J; Drulovic, J; Dujmovic, I; Voortman, M; Khalil, M; Gil, E; Navarro, L; Álvarez-Cermeño, JC; Montalban, X; Comabella, M Cerebrospinal fluid mitochondrial DNA levels in patients with multiple sclerosis.
Mult Scler. 2019; 25(11):1535-1538
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Gottschalk, B; Klec, C; Leitinger, G; Bernhart, E; Rost, R; Bischof, H; Madreiter-Sokolowski, CT; Radulović, S; Eroglu, E; Sattler, W; Waldeck-Weiermair, M; Malli, R; Graier, WF MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex.
Nat Commun. 2019; 10(1):3732-3732 [OPEN ACCESS]
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Hofer, DC; Zirkovits, G; Pelzmann, HJ; Huber, K; Pessentheiner, AR; Xia, W; Uno, K; Miyazaki, T; Kon, K; Tsuneki, H; Pendl, T; Al Zoughbi, W; Madreiter-Sokolowski, CT; Trausinger, G; Abdellatif, M; Schoiswohl, G; Schreiber, R; Eisenberg, T; Magnes, C; Sedej, S; Eckhardt, M; Sasahara, M; Sasaoka, T; Nitta, A; Hoefler, G; Graier, WF; Kratky, D; Auwerx, J; Bogner-Strauss, JG N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
FASEB J. 2019; fj201801323R-fj201801323R [OPEN ACCESS]
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Huber, K; Hofer, DC; Trefely, S; Pelzmann, HJ; Madreiter-Sokolowski, C; Duta-Mare, M; Schlager, S; Trausinger, G; Stryeck, S; Graier, WF; Kolb, D; Magnes, C; Snyder, NW; Prokesch, A; Kratky, D; Madl, T; Wellen, KE; Bogner-Strauss, JG N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
Biochim Biophys Acta Mol Cell Res. 2019; 1866(3): 337-348. [OPEN ACCESS]
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Klec, C; Madreiter-Sokolowski, CT; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells.
Cell Physiol Biochem. 2019; 52(1): 57-75. [OPEN ACCESS]
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Klec, C; Madreiter-Sokolowski, CT; Ziomek, G; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Presenilin-1 Established ER-Ca2+ Leak: a Follow Up on Its Importance for the Initial Insulin Secretion in Pancreatic Islets and β-Cells upon Elevated Glucose.
Cell Physiol Biochem. 2019; 53(3): 573-586. [OPEN ACCESS]
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Klec, C; Ziomek, G; Pichler, M; Malli, R; Graier, WF Calcium Signaling in ß-cell Physiology and Pathology: A Revisit.
Int J Mol Sci. 2019; 20(24): [OPEN ACCESS]
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Koentges, C; Cimolai, MC; Pfeil, K; Wolf, D; Marchini, T; Tarkhnishvili, A; Hoffmann, MM; Odening, KE; Diehl, P; von Zur Mühlen, C; Alvarez, S; Bode, C; Zirlik, A; Bugger, H Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
J Mol Cell Cardiol. 2019; 133(1):138-147
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Madreiter-Sokolowski, CT; Malli, RM; Graier, WF Mitochondrial-Endoplasmic Reticulum Interplay: A Lifelong On-Off Relationship?
Contact (Thousand Oaks). 2019; 2: 2515256419861227-2515256419861227. [OPEN ACCESS]
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Madreiter-Sokolowski, CT; Ramadani-Muja, J; Ziomek, G; Burgstaller, S; Bischof, H; Koshenov, Z; Gottschalk, B; Malli, R; Graier, WF Tracking intra- and inter-organelle signaling of mitochondria.
FEBS J. 2019; 286(22):4378-4401 [OPEN ACCESS]
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Madreiter-Sokolowski, CT; Waldeck-Weiermair, M; Bourguignon, MP; Villeneuve, N; Gottschalk, B; Klec, C; Stryeck, S; Radulovic, S; Parichatikanond, W; Frank, S; Madl, T; Malli, R; Graier, WF Enhanced inter-compartmental Ca2+ flux modulates mitochondrial metabolism and apoptotic threshold during aging.
Redox Biol. 2019; 20:458-466 [OPEN ACCESS]
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Ong, SB; Lee, WH; Shao, NY; Ismail, NI; Katwadi, K; Lim, MM; Kwek, XY; Michel, NA; Li, J; Newson, J; Tahmasebi, S; Rehman, J; Kodo, K; Jang, HR; Ong, SG Calpain Inhibition Restores Autophagy and Prevents Mitochondrial Fragmentation in a Human iPSC Model of Diabetic Endotheliopathy.
Stem Cell Reports. 2019; 12(3):597-610 [OPEN ACCESS]
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Parey, K; Haapanen, O; Sharma, V; Köfeler, H; Züllig, T; Prinz, S; Siegmund, K; Wittig, I; Mills, DJ; Vonck, J; Kühlbrandt, W; Zickermann, V High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease.
Sci Adv. 2019; 5(12): eaax9484-eaax9484. [OPEN ACCESS]
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Pepin, ME; Koentges, C; Pfeil, K; Gollmer, J; Kersting, S; Wiese, S; Hoffmann, MM; Odening, KE; von zur Muhlen, C; Diehl, P; Stachon, P; Wolt, D; Wende, AR; Bode, C; Zirlik, A; Bugger, H Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1
FRONT ENDOCRINOL. 2019; 10: 872 [OPEN ACCESS]
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Ramadani-Muja, J; Gottschalk, B; Pfeil, K; Burgstaller, S; Rauter, T; Bischof, H; Waldeck-Weiermair, M; Bugger, H; Graier, WF; Malli, R Visualization of Sirtuin 4 Distribution between Mitochondria and the Nucleus, Based on Bimolecular Fluorescence Self-Complementation.
Cells. 2019; 8(12): [OPEN ACCESS]
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Rao, S; Mondragón, L; Pranjic, B; Hanada, T; Stoll, G; Köcher, T; Zhang, P; Jais, A; Lercher, A; Bergthaler, A; Schramek, D; Haigh, K; Sica, V; Leduc, M; Modjtahedi, N; Pai, TP; Onji, M; Uribesalgo, I; Hanada, R; Kozieradzki, I; Koglgruber, R; Cronin, SJ; She, Z; Quehenberger, F; Popper, H; Kenner, L; Haigh, JJ; Kepp, O; Rak, M; Cai, K; Kroemer, G; Penninger, JM AIF-regulated oxidative phosphorylation supports lung cancer development.
Cell Res. 2019; [OPEN ACCESS]
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Sharkia, R; Wierenga, KJ; Kessel, A; Azem, A; Bertini, E; Carrozzo, R; Torraco, A; Goffrini, P; Ceccatelli Berti, C; McCormick, ME; Plecko, B; Klein, A; Abela, L; Hengel, H; Schöls, L; Shalev, S; Khayat, M; Mahajnah, M; Spiegel, R Clinical, radiological, and genetic characteristics of 16 patients with ACO2 gene defects: Delineation of an emerging neurometabolic syndrome.
J INHERIT METAB DIS. 2019; 42(2): 264-275.
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Theiler, A; Bärnthaler, T; Platzer, W; Richtig, G; Peinhaupt, M; Rittchen, S; Kargl, J; Ulven, T; Marsh, LM; Marsche, G; Schuligoi, R; Sturm, EM; Heinemann, A Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.
J Allergy Clin Immunol. 2019; 144(3):764-776 [OPEN ACCESS]
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Waich, S; Roscher, A; Brunner-Krainz, M; Cortina, G; Köstl, G; Feichtinger, RG; Entenmann, A; Müller, T; Knisely, AS; Mayr, JA; Janecke, AR; Vodopiutz, J Severe Deoxyguanosine Kinase Deficiency in Austria: A 6-Patient Series.
J Pediatr Gastroenterol Nutr. 2019; 68(1):e1-e6-e1-e6
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Waldeck-Weiermair, M; Gottschalk, B; Madreiter-Sokolowski, CT; Ramadani-Muja, J; Ziomek, G; Klec, C; Burgstaller, S; Bischof, H; Depaoli, MR; Eroglu, E; Malli, R; Graier, WF Development and Application of Sub-Mitochondrial Targeted Ca2 + Biosensors.
Front Cell Neurosci. 2019; 13: 449-449. [OPEN ACCESS]
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Wang, Z; Jiang, SF; Cao, J; Liu, K; Xu, SH; Arfat, Y; Guo, QL; Chang, H; Goswami, N; Hinghofer-Szalkay, H; Gao, YF Novel findings on ultrastructural protection of skeletal muscle fibers during hibernation of Daurian ground squirrels: Mitochondria, nuclei, cytoskeleton, glycogen.
J Cell Physiol. 2019; 234(8):13318-13331
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Wei, W; Tuna, S; Keogh, MJ; Smith, KR; Aitman, TJ; Beales, PL; Bennett, DL; Gale, DP; Bitner-Glindzicz, MAK; Black, GC; Brennan, P; Elliott, P; Flinter, FA; Floto, RA; Houlden, H; Irving, M; Koziell, A; Maher, ER; Markus, HS; Morrell, NW; Newman, WG; Roberts, I; Sayer, JA; Smith, KGC; Taylor, JC; Watkins, H; Webster, AR; Wilkie, AOM; Williamson, C; NIHR BioResource–Rare Diseases; 100,000 Genomes Project–Rare Diseases Pilot; Ashford, S; Penkett, CJ; Stirrups, KE; Rendon, A; Ouwehand, WH; Bradley, JR; Raymond, FL; Caulfield, M; Turro, E; Chinnery, PF Germline selection shapes human mitochondrial DNA diversity.
Science. 2019; 364(6442): [OPEN ACCESS]
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Wilson, MP; Plecko, B; Mills, PB; Clayton, PT Disorders affecting vitamin B6 metabolism.
J Inherit Metab Dis. 2019; 42(4):629-646 [OPEN ACCESS]
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Wodlej, C; Riedl, S; Rinner, B; Leber, R; Drechsler, C; Voelker, DR; Choi, JY; Lohner, K; Zweytick, D Interaction of two antitumor peptides with membrane lipids - Influence of phosphatidylserine and cholesterol on specificity for melanoma cells.
PLoS One. 2019; 14(1): e0211187-e0211187. [OPEN ACCESS]
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Yong, J; Bischof, H; Burgstaller, S; Siirin, M; Murphy, A; Malli, R; Kaufman, RJ Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2.
Elife. 2019; 8: [OPEN ACCESS]
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2018

Alfadhel, M; Nashabat, M; Alrifai, MT; Alshaalan, H; Al Mutairi, F; Al-Shahrani, SA; Plecko, B; Almass, R; Alsagob, M; Almutairi, FB; Al-Rumayyan, A; Al-Twaijri, W; Al-Owain, M; Taylor, RW; Kaya, N Further delineation of the phenotypic spectrum of ISCA2 defect: A report of ten new cases.
Eur J Paediatr Neurol. 2018; 22(1): 46-55.
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Alkan, HF; Walter, KE; Luengo, A; Madreiter-Sokolowski, CT; Stryeck, S; Lau, AN; Al-Zoughbi, W; Lewis, CA; Thomas, CJ; Hoefler, G; Graier, WF; Madl, T; Vander Heiden, MG; Bogner-Strauss, JG Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.
Cell Metab. 2018; 28(5):706-720 [OPEN ACCESS]
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Augustin, P; Toplak, M; Fuchs, K; Gerstmann, EC; Prassl, R; Winkler, A; Macheroux, P Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein.
J Biol Chem. 2018; 293(8): 2829-2840. [OPEN ACCESS]
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Bernhart, E; Kogelnik, N; Prasch, J; Gottschalk, B; Goeritzer, M; Depaoli, MR; Reicher, H; Nusshold, C; Plastira, I; Hammer, A; Fauler, G; Malli, R; Graier, WF; Malle, E; Sattler, W 2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Redox Biol. 2018; 15:441-451 [OPEN ACCESS]
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Depaoli, MR; Karsten, F; Madreiter-Sokolowski, CT; Klec, C; Gottschalk, B; Bischof, H; Eroglu, E; Waldeck-Weiermair, M; Simmen, T; Graier, WF; Malli, R Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells.
Cell Rep. 2018; 25(2):501-512 [OPEN ACCESS]
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Diehl, P; Gaul, DS; Sogl, J; Flierl, U; Henstridge, D; Pahla, J; Bugger, H; Emmert, MY; Ruschitzka, F; Bode, C; Lüscher, TF; Moser, M; Matter, CM; Peter, K; Winnik, S The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts.
J Thromb Thrombolysis. 2018; 46(1): 102-112.
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Duta-Mare, M; Sachdev, V; Leopold, C; Kolb, D; Vujic, N; Korbelius, M; Hofer, DC; Xia, W; Huber, K; Auer, M; Gottschalk, B; Magnes, C; Graier, WF; Prokesch, A; Radovic, B; Bogner-Strauss, JG; Kratky, D Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Biochim Biophys Acta. 2018; 1863(4):467-478 [OPEN ACCESS]
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