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Search Items: MITOCHONDRIA - DRUG EFFECTS , . hits: 34

2018

Hager, S; Korbula, K; Bielec, B; Grusch, M; Pirker, C; Schosserer, M; Liendl, L; Lang, M; Grillari, J; Nowikovsky, K; Pape, VFS; Mohr, T; Szakács, G; Keppler, BK; Berger, W; Kowol, CR; Heffeter, P The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition.
Cell Death Dis. 2018; 9(11):1052-1052 [OPEN ACCESS]
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Jahanafrooz, Z; Stallinger, A; Anders, I; Kleinegger, F; Lohberger, B; Durchschein, C; Bauer, R; Deutsch, A; Rinner, B; Kretschmer, N Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
Phytomedicine. 2018; 49(11):32-40
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Kretschmer, N; Deutsch, A; Durchschein, C; Rinner, B; Stallinger, A; Higareda-Almaraz, JC; Scheideler, M; Lohberger, B; Bauer, R Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction.
Molecules. 2018; 23(11): [OPEN ACCESS]
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Mkrtchyan, GV; Üçal, M; Müllebner, A; Dumitrescu, S; Kames, M; Moldzio, R; Molcanyi, M; Schaefer, S; Weidinger, A; Schaefer, U; Hescheler, J; Duvigneau, JC; Redl, H; Bunik, VI; Kozlov, AV Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex.
BBA - Bioenergetics. 2018; 1859(9): 925-931. [OPEN ACCESS]
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2017

Madreiter-Sokolowski, CT; Sokolowski, AA; Graier, WF Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria.
Nutrients. 2017; 9(10): [OPEN ACCESS]
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2016

Madreiter-Sokolowski, CT; Gottschalk, B; Parichatikanond, W; Eroglu, E; Klec, C; Waldeck-Weiermair, M; Malli, R; Graier, WF Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria.
Cell Physiol Biochem. 2016; 39(4):1404-1420 [OPEN ACCESS]
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2015

Neve, EP; Köfeler, H; Hendriks, DF; Nordling, Å; Gogvadze, V; Mkrtchian, S; Näslund, E; Ingelman-Sundberg, M Expression and Function of mARC: Roles in Lipogenesis and Metabolic Activation of Ximelagatran.
PLoS One. 2015; 10(9):e0138487-e0138487 [OPEN ACCESS]
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Teubl, BJ; Schimpel, C; Leitinger, G; Bauer, B; Fröhlich, E; Zimmer, A; Roblegg, E Interactions between nano-TiO2 and the oral cavity: impact of nanomaterial surface hydrophilicity/hydrophobicity.
J Hazard Mater. 2015; 286(12):298-305
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2014

Fröhlich, LF; Mrakovcic, M; Smole, C; Lahiri, P; Zatloukal, K Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells.
PLoS One. 2014; 9(3):e91558-e91558 [OPEN ACCESS]
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Kozina, A; Opresnik, S; Wong, MS; Hallström, S; Graier, WF; Malli, R; Schröder, K; Schmidt, K; Frank, S Oleoyl-lysophosphatidylcholine limits endothelial nitric oxide bioavailability by induction of reactive oxygen species.
PLoS One. 2014; 9(11):e113443-e113443 [OPEN ACCESS]
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2013

Bosche, B; Schäfer, M; Graf, R; Härtel, FV; Schäfer, U; Noll, T Lithium prevents early cytosolic calcium increase and secondary injurious calcium overload in glycolytically inhibited endothelial cells.
Biochem Biophys Res Commun. 2013; 434(2):268-272
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Cekauskas, A; Bruns, H; Manikas, M; Herr, I; Gross, ML; Zorn, M; Jankevicius, F; Strupas, K; Schemmer, P Sulforaphane decreases kidney injury after transplantation in rats: role of mitochondrial damage.
Ann Transplant. 2013; 18(3-4):488-496 [OPEN ACCESS]
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Fröhlich, E Cellular targets and mechanisms in the cytotoxic action of non-biodegradable engineered nanoparticles.
Curr Drug Metab. 2013; 14(9):976-988 [OPEN ACCESS]
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Nikam, A; Patankar, JV; Lackner, C; Schöck, E; Kratky, D; Zatloukal, K; Abuja, PM Transition between acute and chronic hepatotoxicity in mice is associated with impaired energy metabolism and induction of mitochondrial heme oxygenase-1.
PLoS One. 2013; 8(6):e66094-e66094 [OPEN ACCESS]
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2012

Aflaki, E; Doddapattar, P; Radovic, B; Povoden, S; Kolb, D; Vujic, N; Wegscheider, M; Koefeler, H; Hornemann, T; Graier, WF; Malli, R; Madeo, F; Kratky, D C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.
Cell Death Dis. 2012; 3(6):e280-e280 [OPEN ACCESS]
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Crnkovic, S; Riederer, M; Lechleitner, M; Hallström, S; Malli, R; Graier, WF; Lindenmann, J; Popper, H; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca²⁺-dependent induction of oxidative stress.
Free Radic Biol Med. 2012; 52(9):1786-1795 [OPEN ACCESS]
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Gemes, G; Oyster, KD; Pan, B; Wu, HE; Bangaru, ML; Tang, Q; Hogan, QH Painful nerve injury increases plasma membrane Ca2+ -ATPase activity in axotomized sensory neurons.
Mol Pain. 2012; 8(12):46-46 [OPEN ACCESS]
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Lefevre, S; Sliwa, D; Auchre, F; Brossas, C; Ruckenstuhl, C; Boggetto, N; Lesuisse, E; Madeo, F; Camadro, JM; Santos, R The yeast metacaspase is implicated in oxidative stress response in frataxin-deficient cells.
FEBS Lett. 2012; 586(2):143-148 [OPEN ACCESS]
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Oberbach, A; Schlichting, N; Heinrich, M; Till, H; Stolzenburg, JU; Neuhaus, J Free fatty acid palmitate impairs the vitality and function of cultured human bladder smooth muscle cells.
PLoS One. 2012; 7(7):e41026-e41026 [OPEN ACCESS]
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Radnai, B; Antus, C; Racz, B; Engelmann, P; Priber, JK; Tucsek, Z; Veres, B; Turi, Z; Lorand, T; Sumegi, B; Gallyas, F Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation.
Mol Cancer. 2012; 11(5): 34-34. [OPEN ACCESS]
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Ullen, A; Fauler, G; Bernhart, E; Nusshold, C; Reicher, H; Leis, HJ; Malle, E; Sattler, W Phloretin ameliorates 2-chlorohexadecanal-mediated brain microvascular endothelial cell dysfunction in vitro.
Free Radic Biol Med. 2012; 53(9):1770-1781 [OPEN ACCESS]
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2011

Bondarenko, OI; Sahach, VF Mitochondrial Na+-Ca2+-exchanger inhibitor CGP37157 produces endothelial cell depolarization with membrane potential oscillations].
Fiziol Zh. 2011; 57(1):9-16
PubMed

 

Fuchs, R; Schraml, E; Leitinger, G; Letofsky-Papst, I; Stelzer, I; Haas, HS; Schauenstein, K; Sadjak, A á1-adrenergic drugs exhibit affinity to a thapsigargin-sensitive binding site and interfere with the intracellular Ca2+ homeostasis in human erythroleukemia cells.
Exp Cell Res. 2011; 317(20):2969-2980
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Sloan, C; Tuinei, J; Nemetz, K; Frandsen, J; Soto, J; Wride, N; Sempokuya, T; Alegria, L; Bugger, H; Abel, ED Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted ob/ob mice.
Diabetes. 2011; 60(5): 1424-1434. [OPEN ACCESS]
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2008

Jousset, H; Malli, R; Girardin, N; Graier, WF; Demaurex, N; Frieden, M Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2) store depletion in endothelial cells.
Cell Calcium. 2008; 43(1): 83-94.
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Majumder, S; Muley, A; Kolluru, GK; Saurabh, S; Tamilarasan, KP; Chandrasekhar, S; Reddy, HB; Purohit, S; Chatterjee, S Cadmium reduces nitric oxide production by impairing phosphorylation of endothelial nitric oxide synthase.
Biochem Cell Biol. 2008; 86(1):1-10
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2005

von Lewinski, F; Keller, BU Mitochondrial Ca2+ buffering in hypoglossal motoneurons from mouse.
Neurosci Lett. 2005; 380(3):203-208
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2004

Bergmann, F; Keller, BU Impact of mitochondrial inhibition on excitability and cytosolic Ca2+ levels in brainstem motoneurones from mouse.
J Physiol. 2004; 555(Pt 1):45-59 [OPEN ACCESS]
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Horwath-Winter, J; Simon, M; Kölli, H; Trummer, G; Schmut, O Cytotoxicity evaluation of soft contact lens care solutions on human conjunctival fibroblasts.
OPHTHALMOLOGICA. 2004; 218(6): 385-389.
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2003

Zoratti, C; Kipmen-Korgun, D; Osibow, K; Malli, R; Graier, WF Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells.
Br J Pharmacol. 2003; 140(8):1351-1362 [OPEN ACCESS]
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2002

Semlitsch, T; Tillian, HM; Zarkovic, N; Borovic, S; Purtscher, M; Hohenwarter, O; Schaur, RJ Differential influence of the lipid peroxidation product 4-hydroxynonenal on the growth of human lymphatic leukaemia cells and human periopherial blood lymphocytes.
Anticancer Res. 2002; 22(3):1689-1697
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Thyagarajan, B; Malli, R; Schmidt, K; Graier, WF; Groschner, K Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling.
Br J Pharmacol. 2002; 137(6):821-830 [OPEN ACCESS]
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2001

Jones, CJ; Weiss, U; Simán, CM; Desoye, G Mitochondria from human trophoblast and embryonic liver cells are resistant to hyperglycaemia-associated high-amplitude swelling.
DIABETOLOGIA 2001 44: 389-391.
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Thyagarajan, B; Poteser, M; Romanin, C; Kahr, H; Zhu, MX; Groschner, K Expression of Trp3 determines sensitivity of capacitative Ca2+ entry to nitric oxide and mitochondrial Ca2+ handling: evidence for a role of Trp3 as a subunit of capacitative Ca2+ entry channels.
J Biol Chem. 2001; 276(51):48149-48158 [OPEN ACCESS]
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