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Search Items: MICE - , . hits: 1166

2019

Grill, M; Hasenoehrl, C; Kienzl, M; Kargl, J; Schicho, R Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation.
Histochem Cell Biol. 2019; 151(1):5-20 [OPEN ACCESS]
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Mokou, M; Klein, J; Makridakis, M; Bitsika, V; Bascands, JL; Saulnier-Blache, JS; Mullen, W; Sacherer, M; Zoidakis, J; Pieske, B; Mischak, H; Roubelakis, MG; Schanstra, JP; Vlahou, A Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease.
EBioMedicine. 2019; 41:91-104 [OPEN ACCESS]
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Philippe, C; Zeilinger, M; Dumanic, M; Pichler, F; Fetty, L; Vraka, C; Balber, T; Wadsak, W; Pallitsch, K; Spreitzer, H; Lanzenberger, R; Hacker, M; Mitterhauser, M SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [18F]FE@SNAP and [11C]SNAP-7941.
Mol Imaging Biol. 2019; 21(2):257-268 [OPEN ACCESS]
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Zhu, XG; Nicholson Puthenveedu, S; Shen, Y; La, K; Ozlu, C; Wang, T; Klompstra, D; Gultekin, Y; Chi, J; Fidelin, J; Peng, T; Molina, H; Hang, HC; Min, W; Birsoy, K CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.
MOL CELL. 2019; 74(1): 45-58. [OPEN ACCESS]
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2018

Anto Michel, N; Colberg, C; Buscher, K; Sommer, B; Pramod, AB; Ehinger, E; Dufner, B; Hoppe, N; Pfeiffer, K; Marchini, T; Willecke, F; Stachon, P; Hilgendorf, I; Heidt, T; von Zur Muhlen, C; von Elverfeldt, D; Pfeifer, D; Schüle, R; Kintscher, U; Brachs, S; Ley, K; Bode, C; Zirlik, A; Wolf, D Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.
Circ Res. 2018; 122(5):693-700 [OPEN ACCESS]
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Basu, D; Hu, Y; Huggins, LA; Mullick, AE; Graham, MJ; Wietecha, T; Barnhart, S; Mogul, A; Pfeiffer, K; Zirlik, A; Fisher, EA; Bornfeldt, KE; Willecke, F; Goldberg, IJ Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor.
Circ Res. 2018; 122(4):560-567 [OPEN ACCESS]
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Folci, A; Steinberger, A; Lee, B; Stanika, R; Scheruebel, S; Campiglio, M; Ramprecht, C; Pelzmann, B; Hell, JW; Obermair, GJ; Heine, M; Di Biase, V Molecular mimicking of C-terminal phosphorylation tunes the surface dynamics of CaV1.2 calcium channels in hippocampal neurons.
J Biol Chem. 2018; 293(3):1040-1053 [OPEN ACCESS]
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Frauscher, B; Kirsch, AH; Schabhüttl, C; Schweighofer, K; Kétszeri, M; Pollheimer, M; Dragun, D; Schröder, K; Rosenkranz, AR; Eller, K; Eller, P Autophagy Protects From Uremic Vascular Media Calcification.
Front Immunol. 2018; 9(5):1866-1866 [OPEN ACCESS]
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Fuchs, CD; Paumgartner, G; Mlitz, V; Kunczer, V; Halilbasic, E; Leditznig, N; Wahlström, A; Ståhlman, M; Thüringer, A; Kashofer, K; Stojakovic, T; Marschall, HU; Trauner, M Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2-/- mice by modulating composition, signalling and excretion of faecal bile acids.
Gut. 2018; 67(9):1683-1691 [OPEN ACCESS]
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Gögele, C; Schwarz, S; Ondruschka, B; Hammer, N; Schulze-Tanzil, G Decellularized Iliotibial Band Recolonized with Allogenic Homotopic Fibroblasts or Bone Marrow-Derived Mesenchymal Stromal Cells.
Methods Mol Biol. 2018; 1577(5):55-69
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Harper, SC; Johnson, J; Borghetti, G; Zhao, H; Wang, T; Wallner, M; Kubo, H; Feldsott, EA; Yang, Y; Joo, Y; Gou, X; Sabri, AK; Gupta, P; Myzithras, M; Khalil, A; Franti, M; Houser, SR GDF11 Decreases Pressure Overload-Induced Hypertrophy, but Can Cause Severe Cachexia and Premature Death.
Circ Res. 2018; 123(11):1220-1231 [OPEN ACCESS]
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Hasenoehrl, C; Feuersinger, D; Sturm, EM; Bärnthaler, T; Heitzer, E; Graf, R; Grill, M; Pichler, M; Beck, S; Butcher, L; Thomas, D; Ferreirós, N; Schuligoi, R; Schweiger, C; Haybaeck, J; Schicho, R G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.
Int J Cancer. 2018; 142(1):121-132 [OPEN ACCESS]
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Leithner, K; Triebl, A; Trötzmüller, M; Hinteregger, B; Leko, P; Wieser, BI; Grasmann, G; Bertsch, AL; Züllig, T; Stacher, E; Valli, A; Prassl, R; Olschewski, A; Harris, AL; Köfeler, HC; Olschewski, H; Hrzenjak, A The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
Proc Natl Acad Sci U S A. 2018; 115(24):6225-6230 [OPEN ACCESS]
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Merz, J; Albrecht, P; von Garlen, S; Ahmed, I; Dimanski, D; Wolf, D; Hilgendorf, I; Härdtner, C; Grotius, K; Willecke, F; Heidt, T; Bugger, H; Hoppe, N; Kintscher, U; von Zur Mühlen, C; Idzko, M; Bode, C; Zirlik, A; Stachon, P Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome.
Basic Res Cardiol. 2018; 113(6):45-45
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Mohsin, NU; Seebacher, W; Faist, J; Hochegger, P; Kaiser, M; Mäser, P; Belaj, F; Saf, R; Kretschmer, N; Alajlani, M; Turek, I; Brantner, A; Bauer, R; Bucar, F; Weis, R Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.
Eur J Med Chem. 2018; 143(8):97-106
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Rengachari, S; Groiss, S; Devos, JM; Caron, E; Grandvaux, N; Panne, D Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.
Proc Natl Acad Sci U S A. 2018; 115(4): E601-E609. [OPEN ACCESS]
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Sukseree, S; László, L; Gruber, F; Bergmann, S; Narzt, MS; Nagelreiter, IM; Höftberger, R; Molnár, K; Rauter, G; Birngruber, T; Larue, L; Kovacs, GG; Tschachler, E; Eckhart, L Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7.
Mol Neurobiol. 2018; 55(11):8425-8437 [OPEN ACCESS]
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Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 [OPEN ACCESS]
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Winkels, H; Ehinger, E; Vassallo, M; Buscher, K; Dinh, HQ; Kobiyama, K; Hamers, AAJ; Cochain, C; Vafadarnejad, E; Saliba, AE; Zernecke, A; Pramod, AB; Ghosh, AK; Anto Michel, N; Hoppe, N; Hilgendorf, I; Zirlik, A; Hedrick, CC; Ley, K; Wolf, D Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.
Circ Res. 2018; 122(12):1675-1688 [OPEN ACCESS]
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Zandl-Lang, M; Fanaee-Danesh, E; Sun, Y; Albrecher, NM; Gali, CC; Čančar, I; Kober, A; Tam-Amersdorfer, C; Stracke, A; Storck, SM; Saeed, A; Stefulj, J; Pietrzik, CU; Wilson, MR; Björkhem, I; Panzenboeck, U Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Biochim Biophys Acta Mol Cell Biol Lipids. 2018; 1863(1):40-60
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2017

Amankulor, NM; Kim, Y; Arora, S; Kargl, J; Szulzewsky, F; Hanke, M; Margineantu, DH; Rao, A; Bolouri, H; Delrow, J; Hockenbery, D; Houghton, AM; Holland, EC Mutant IDH1 regulates the tumor-associated immune system in gliomas.
Genes Dev. 2017; 31(8):774-786 [OPEN ACCESS]
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Artinger, K; Kirsch, AH; Aringer, I; Moschovaki-Filippidou, F; Eller, P; Rosenkranz, AR; Eller, K Innate and adaptive immunity in experimental glomerulonephritis: a pathfinder tale.
Pediatr Nephrol. 2017; 32(6):943-947 [OPEN ACCESS]
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Baar, MP; Brandt, RMC; Putavet, DA; Klein, JDD; Derks, KWJ; Bourgeois, BRM; Stryeck, S; Rijksen, Y; van Willigenburg, H; Feijtel, DA; van der Pluijm, I; Essers, J; van Cappellen, WA; van IJcken, WF; Houtsmuller, AB; Pothof, J; de Bruin, RWF; Madl, T; Hoeijmakers, JHJ; Campisi, J; de Keizer, PLJ Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Cell. 2017; 169(1):132-147 [OPEN ACCESS]
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Baker, D; Pryce, G; Visintin, C; Sisay, S; Bondarenko, AI; Vanessa Ho, WS; Jackson, SJ; Williams, TE; Al-Izki, S; Sevastou, I; Okuyama, M; Graier, WF; Stevenson, LA; Tanner, C; Ross, R; Pertwee, RG; Henstridge, CM; Irving, AJ; Schulman, J; Powell, K; Baker, MD; Giovannoni, G; Selwood, DL Big conductance calcium-activated potassium channel openers control spasticity without sedation.
Br J Pharmacol. 2017; 174(16):2662-2681 [OPEN ACCESS]
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Bast, A; Kubis, H; Holtfreter, B; Ribback, S; Martin, H; Schreiner, HC; Dominik, MJ; Breitbach, K; Dombrowski, F; Kocher, T; Steinmetz, I NADPH Oxidase Contributes to Resistance against Aggregatibacter actinomycetemcomitans-Induced Periodontitis in Mice.
Infect Immun. 2017; 85(2): [OPEN ACCESS]
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Bayraktar, R; Pichler, M; Kanlikilicer, P; Ivan, C; Bayraktar, E; Kahraman, N; Aslan, B; Oguztuzun, S; Ulasli, M; Arslan, A; Calin, G; Lopez-Berestein, G; Ozpolat, B MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase.
Oncotarget. 2017; 8(7):11641-11658 [OPEN ACCESS]
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Bedau, T; Peters, F; Prox, J; Arnold, P; Schmidt, F; Finkernagel, M; Köllmann, S; Wichert, R; Otte, A; Ohler, A; Stirnberg, M; Lucius, R; Koudelka, T; Tholey, A; Biasin, V; Pietrzik, CU; Kwapiszewska, G; Becker-Pauly, C Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration.
FASEB J. 2017; 31(3):1226-1237
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Biasin, V; Wygrecka, M; Marsh, LM; Becker-Pauly, C; Brcic, L; Ghanim, B; Klepetko, W; Olschewski, A; Kwapiszewska, G Meprin β contributes to collagen deposition in lung fibrosis.
Sci Rep. 2017; 7(1):39969-39969 [OPEN ACCESS]
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Bischof, H; Rehberg, M; Stryeck, S; Artinger, K; Eroglu, E; Waldeck-Weiermair, M; Gottschalk, B; Rost, R; Deak, AT; Niedrist, T; Vujic, N; Lindermuth, H; Prassl, R; Pelzmann, B; Groschner, K; Kratky, D; Eller, K; Rosenkranz, AR; Madl, T; Plesnila, N; Graier, WF; Malli, R Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.
Nat Commun. 2017; 8(1):1422-1422 [OPEN ACCESS]
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Bonyadi Rad, E; Mostofi, S; Katschnig, M; Schmutz, P; Pawelkiewicz, M; Willumeit-Römer, R; Schäfer, U; Weinberg, A Differential apoptotic response of MC3T3-E1 pre-osteoblasts to biodegradable magnesium alloys in an in vitro direct culture model.
J Mater Sci Mater Med. 2017; 28(10):155-155 [OPEN ACCESS]
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Buerger, C; Shirsath, N; Lang, V; Berard, A; Diehl, S; Kaufmann, R; Boehncke, WH; Wolf, P Inflammation dependent mTORC1 signaling interferes with the switch from keratinocyte proliferation to differentiation.
PLoS One. 2017; 12(7):e0180853-e0180853 [OPEN ACCESS]
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Byrgazov, K; Kastner, R; Gorna, M; Hoermann, G; Koenig, M; Lucini, CB; Ulreich, R; Benesch, M; Strenger, V; Lackner, H; Schwinger, W; Sovinz, P; Haas, OA; van den Heuvel-Eibrink, M; Niemeyer, CM; Hantschel, O; Valent, P; Superti-Furga, G; Urban, C; Dworzak, MN; Lion, T NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors.
Leukemia. 2017; 31(1):237-240 [OPEN ACCESS]
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Castellani, C; Singer, G; Kaiser, M; Kaiser, T; Huang, J; Sperl, D; Kashofer, K; Fauler, G; Guertl-Lackner, B; Höfler, G; Till, H Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition.
Pediatr Blood Cancer. 2017; 64(8):
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Claudia, M; Kristin, Ö; Jennifer, O; Eva, R; Eleonore, F Comparison of fluorescence-based methods to determine nanoparticle uptake by phagocytes and non-phagocytic cells in vitro.
Toxicology. 2017; 378(2):25-36 [OPEN ACCESS]
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Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285 [OPEN ACCESS]
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Deutsch, AJA; Rinner, B; Pichler, M; Prochazka, K; Pansy, K; Bischof, M; Fechter, K; Hatzl, S; Feichtinger, J; Wenzl, K; Frisch, MT; Stiegelbauer, V; Prokesch, A; Krogsdam, A; Sill, H; Thallinger, GG; Greinix, HT; Wang, C; Beham-Schmid, C; Neumeister, P NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.
Cancer Res. 2017; 77(9):2375-2386 [OPEN ACCESS]
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Ding, X; Su, Y; Wang, C; Zhang, F; Chen, K; Wang, Y; Li, M; Wang, W Synergistic Suppression of Tumor Angiogenesis by the Co-delivering of Vascular Endothelial Growth Factor Targeted siRNA and Candesartan Mediated by Functionalized Carbon Nanovectors.
ACS Appl Mater Interfaces. 2017; 9(28): 23353-23369.
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Dobsak, T; Heimel, P; Tangl, S; Schwarze, UY; Schett, G; Gruber, R Impaired periodontium and temporomandibular joints in tumour necrosis factor-α transgenic mice.
J Clin Periodontol. 2017; 44(12):1226-1235
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Duchene, J; Novitzky-Basso, I; Thiriot, A; Casanova-Acebes, M; Bianchini, M; Etheridge, SL; Hub, E; Nitz, K; Artinger, K; Eller, K; Caamaño, J; Rülicke, T; Moss, P; Megens, RTA; von Andrian, UH; Hidalgo, A; Weber, C; Rot, A Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
Nat Immunol. 2017; 18(7):753-761 [OPEN ACCESS]
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Edlinger, L; Berger-Becvar, A; Menzl, I; Hoermann, G; Greiner, G; Grundschober, E; Bago-Horvath, Z; Al-Zoughbi, W; Hoefler, G; Brostjan, C; Gille, L; Moriggl, R; Spittler, A; Sexl, V; Hoelbl-Kovacic, A Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1.
Br J Haematol. 2017; 179(2):229-241 [OPEN ACCESS]
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El Agha, E; Moiseenko, A; Kheirollahi, V; De Langhe, S; Crnkovic, S; Kwapiszewska, G; Szibor, M; Kosanovic, D; Schwind, F; Schermuly, RT; Henneke, I; MacKenzie, B; Quantius, J; Herold, S; Ntokou, A; Ahlbrecht, K; Braun, T; Morty, RE; Günther, A; Seeger, W; Bellusci, S Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.
Cell Stem Cell. 2017; 20(2):261-273 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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Fuchs, CD; Paumgartner, G; Wahlström, A; Schwabl, P; Reiberger, T; Leditznig, N; Stojakovic, T; Rohr-Udilova, N; Chiba, P; Marschall, HU; Trauner, M Metabolic preconditioning protects BSEP/ABCB11-/- mice against cholestatic liver injury.
J Hepatol. 2017; 66(1):95-101 [OPEN ACCESS]
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Geuens, T; De Winter, V; Rajan, N; Achsel, T; Mateiu, L; Almeida-Souza, L; Asselbergh, B; Bouhy, D; Auer-Grumbach, M; Bagni, C; Timmerman, V Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
Acta Neuropathol Commun. 2017; 5(1):5-5 [OPEN ACCESS]
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Grabiec, U; Hohmann, T; Hammer, N; Dehghani, F Organotypic Hippocampal Slice Cultures As a Model to Study Neuroprotection and Invasiveness of Tumor Cells.
J Vis Exp. 2017; 31(126): [OPEN ACCESS]
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Grond, S; Eichmann, TO; Dubrac, S; Kolb, D; Schmuth, M; Fischer, J; Crumrine, D; Elias, PM; Haemmerle, G; Zechner, R; Lass, A; Radner, FPW PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.
J Invest Dermatol. 2017; 137(2):394-402 [OPEN ACCESS]
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Grond, S; Radner, FPW; Eichmann, TO; Kolb, D; Grabner, GF; Wolinski, H; Gruber, R; Hofer, P; Heier, C; Schauer, S; Rülicke, T; Hoefler, G; Schmuth, M; Elias, PM; Lass, A; Zechner, R; Haemmerle, G Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.
J Invest Dermatol. 2017; 137(2):403-413 [OPEN ACCESS]
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Gruber, R; Rogerson, C; Windpassinger, C; Banushi, B; Straatman-Iwanowska, A; Hanley, J; Forneris, F; Strohal, R; Ulz, P; Crumrine, D; Menon, GK; Blunder, S; Schmuth, M; Müller, T; Smith, H; Mills, K; Kroisel, P; Janecke, AR; Gissen, P Autosomal Recessive Keratoderma-Ichthyosis-Deafness (ARKID) Syndrome Is Caused by VPS33B Mutations Affecting Rab Protein Interaction and Collagen Modification.
J Invest Dermatol. 2017; 137(4):845-854 [OPEN ACCESS]
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Hanley, J; Dhar, DK; Mazzacuva, F; Fiadeiro, R; Burden, JJ; Lyne, AM; Smith, H; Straatman-Iwanowska, A; Banushi, B; Virasami, A; Mills, K; Lemaigre, FP; Knisely, AS; Howe, S; Sebire, N; Waddington, SN; Paulusma, CC; Clayton, P; Gissen, P Vps33b is crucial for structural and functional hepatocyte polarity.
J Hepatol. 2017; 66(5):1001-1011 [OPEN ACCESS]
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Hartler, J; Triebl, A; Ziegl, A; Trötzmüller, M; Rechberger, GN; Zeleznik, OA; Zierler, KA; Torta, F; Cazenave-Gassiot, A; Wenk, MR; Fauland, A; Wheelock, CE; Armando, AM; Quehenberger, O; Zhang, Q; Wakelam, MJO; Haemmerle, G; Spener, F; Köfeler, HC; Thallinger, GG Deciphering lipid structures based on platform-independent decision rules.
Nat Methods. 2017; 14(12): 1171-1174. [OPEN ACCESS]
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