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Search Items: INFLAMMATION - METABOLISM , . hits: 89

2023

Delgobo, M; Weiß, E; Ashour, D; Richter, L; Popiolkowski, L; Arampatzi, P; Stangl, V; Arias-Loza, P; Mariotti-Ferrandiz, E; Rainer, PP; Saliba, AE; Ludewig, B; Hofmann, U; Frantz, S; Campos, Ramos, G Myocardial Milieu Favors Local Differentiation of Regulatory T Cells.
Circ Res. 2023; 132(5):565-582 Doi: 10.1161/CIRCRESAHA.122.322183
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Krysko, O; Korsakova, D; Teufelberger, A; De, Meyer, A; Steels, J; De, Ruyck, N; van, Ovost, J; Van, Nevel, S; Holtappels, G; Coppieters, F; Ivanchenko, M; Braun, H; Vedunova, M; Krysko, DV; Bachert, C Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice.
Front Immunol. 2023; 14: 1040493 Doi: 10.3389/fimmu.2023.1040493 [OPEN ACCESS]
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2022

Birnhuber, A; Jandl, K; Biasin, V; Fließer, E; Valzano, F; Marsh, LM; Krolczik, C; Olschewski, A; Wilhelm, J; Toller, W; Heinemann, A; Olschewski, H; Wygrecka, M; Kwapiszewska, G Pirfenidone exacerbates Th2-driven vasculopathy in a mouse model of systemic sclerosis-associated interstitial lung disease.
Eur Respir J. 2022; 60(4): Doi: 10.1183/13993003.02347-2021 [OPEN ACCESS]
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Hochgerner, M; Bauer, T; Zyulina, V; Glitzner, E; Warsi, S; Konkel, JE; Tam-Amersdorfer, C; Chen, W; Karlsson, S; Sibilia, M; Strobl, H BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207⁺ Langerhans Cell Differentiation and Limits Skin Inflammation through CD11c⁺ Cells.
J Invest Dermatol. 2022; 142(9):2446-2454.e3 Doi: 10.1016/j.jid.2022.02.014
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Joshi, L; Plastira, I; Bernhart, E; Reicher, H; Koshenov, Z; Graier, WF; Vujic, N; Kratky, D; Rivera, R; Chun, J; Sattler, W Lysophosphatidic Acid Receptor 5 (LPA₅) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro.
Cells. 2022; 11(7): Doi: 10.3390/cells11071071 [OPEN ACCESS]
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Koser, F; Hobbach, AJ; Abdellatif, M; Herbst, V; Türk, C; Reinecke, H; Krüger, M; Sedej, S; Linke, WA Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment.
Life Sci. 2022; 309:120998 Doi: 10.1016/j.lfs.2022.120998
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Kraft, JD; Blomgran, R; Bergström, I; Soták, M; Clark, M; Rani, A; Rajan, MR; Dalli, J; Nyström, S; Quiding-Järbrink, M; Bromberg, J; Skoog, P; Börgeson, E Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis.
FASEB J. 2022; 36(3): e22173 Doi: 10.1096/fj.202101219RR [OPEN ACCESS]
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Lukenaite, B; Griciune, E; Leber, B; Strupas, K; Stiegler, P; Schemmer, P Necroptosis in Solid Organ Transplantation: A Literature Overview.
Int J Mol Sci. 2022; 23(7): Doi: 10.3390/ijms23073677 [OPEN ACCESS]
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Schnoegl, D; Hochgerner, M; Gotthardt, D; Marsh, LM Fra-2 Is a Dominant Negative Regulator of Natural Killer Cell Development.
FRONT IMMUNOL. 2022; 13: 909270 Doi: 10.3389/fimmu.2022.909270 [OPEN ACCESS]
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Valadez-Cosmes, P; Raftopoulou, S; Mihalic, ZN; Marsche, G; Kargl, J Myeloperoxidase: Growing importance in cancer pathogenesis and potential drug target.
Pharmacol Ther. 2022; 236:108052 Doi: 10.1016/j.pharmthera.2021.108052
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2021

Chen, J; Haase, N; Haange, SB; Sucher, R; Münzker, J; Jäger, E; Schischke, K; Seyfried, F; von, Bergen, M; Hankir, MK; Krügel, U; Fenske, WK Roux-en-Y gastric bypass contributes to weight loss-independent improvement in hypothalamic inflammation and leptin sensitivity through gut-microglia-neuron-crosstalk.
Mol Metab. 2021; 48:101214 Doi: 10.1016/j.molmet.2021.101214 [OPEN ACCESS]
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Kasatkina, LA; Rittchen, S; Sturm, EM Neuroprotective and Immunomodulatory Action of the Endocannabinoid System under Neuroinflammation.
Int J Mol Sci. 2021; 22(11): Doi: 10.3390/ijms22115431 [OPEN ACCESS]
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2020

Che, J; Najer, A; Blakney, AK; McKay, PF; Bellahcene, M; Winter, CW; Sintou, A; Tang, J; Keane, TJ; Schneider, MD; Shattock, RJ; Sattler, S; Stevens, MM Neutrophils Enable Local and Non-Invasive Liposome Delivery to Inflamed Skeletal Muscle and Ischemic Heart.
Adv Mater. 2020; 32(48): e2003598 Doi: 10.1002/adma.202003598 [OPEN ACCESS]
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2019

Grill, M; Hasenoehrl, C; Kienzl, M; Kargl, J; Schicho, R Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation.
Histochem Cell Biol. 2019; 151(1):5-20 Doi: 10.1007/s00418-018-1719-0 [OPEN ACCESS]
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Gualtieri, F; Nowakowska, M; von, Rüden, EL; Seiffert, I; Potschka, H Epileptogenesis-Associated Alterations of Heat Shock Protein 70 in a Rat Post-Status Epilepticus Model.
Neuroscience. 2019; 415: 44-58. Doi: 10.1016/j.neuroscience.2019.06.031
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Hughes, MM; Hooftman, A; Angiari, S; Tummala, P; Zaslona, Z; Runtsch, MC; McGettrick, AF; Sutton, CE; Diskin, C; Rooke, M; Takahashi, S; Sundararaj, S; Casarotto, MG; Dahlstrom, JE; Palsson-McDermott, EM; Corr, SC; Mills, KHG; Preston, RJS; Neamati, N; Xie, Y; Baell, JB; Board, PG; O'Neill, LAJ Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
Cell Rep. 2019; 29(1): 151-161. Doi: 10.1016/j.celrep.2019.08.072 [OPEN ACCESS]
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Nonn, O; Güttler, J; Forstner, D; Maninger, S; Zadora, J; Balogh, A; Frolova, A; Glasner, A; Herse, F; Gauster, M Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction.
Int J Mol Sci. 2019; 20(3): Doi: 10.3390/ijms20030641 [OPEN ACCESS]
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Pipper, C; Bordag, N; Reiter, B; Economides, K; Florian, P; Birngruber, T; Sinner, F; Bodenlenz, M; Eberl, A LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation.
J Lipid Res. 2019; 60(4):758-766 Doi: 10.1194/jlr.M087221 [OPEN ACCESS]
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2018

Early, JO; Menon, D; Wyse, CA; Cervantes-Silva, MP; Zaslona, Z; Carroll, RG; Palsson-McDermott, EM; Angiari, S; Ryan, DG; Corcoran, SE; Timmons, G; Geiger, SS; Fitzpatrick, DJ; O'Connell, D; Xavier, RJ; Hokamp, K; O'Neill, LAJ; Curtis, AM Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.
Proc Natl Acad Sci U S A. 2018; 115(36): E8460-E8468. Doi: 10.1073/pnas.1800431115 [OPEN ACCESS]
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Emma, R; Bansal, AT; Kolmert, J; Wheelock, CE; Dahlen, SE; Loza, MJ; De, Meulder, B; Lefaudeux, D; Auffray, C; Dahlen, B; Bakke, PS; Chanez, P; Fowler, SJ; Horvath, I; Montuschi, P; Krug, N; Sanak, M; Sandstrom, T; Shaw, DE; Fleming, LJ; Djukanovic, R; Howarth, PH; Singer, F; Sousa, AR; Sterk, PJ; Corfield, J; Pandis, I; Chung, KF; Adcock, IM; Lutter, R; Fabbella, L; Caruso, M, , U-BIOPRED, Study, Group Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort.
PLoS One. 2018; 13(9):e0203874 Doi: 10.1371/journal.pone.0203874 [OPEN ACCESS]
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Korten, I; Liechti, M; Singer, F; Hafen, G; Rochat, I; Anagnostopoulou, P; Müller-Suter, D; Usemann, J; Moeller, A; Frey, U; Latzin, P; Casaulta, C, , SCILD, and, BILD, study, group Lower exhaled nitric oxide in infants with Cystic Fibrosis compared to healthy controls.
J Cyst Fibros. 2018; 17(1):105-108 Doi: 10.1016/j.jcf.2017.05.005
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Merz, J; Albrecht, P; von Garlen, S; Ahmed, I; Dimanski, D; Wolf, D; Hilgendorf, I; Härdtner, C; Grotius, K; Willecke, F; Heidt, T; Bugger, H; Hoppe, N; Kintscher, U; von Zur Mühlen, C; Idzko, M; Bode, C; Zirlik, A; Stachon, P Purinergic receptor Y₂ (P2Y₂)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome.
Basic Res Cardiol. 2018; 113(6):45-45 Doi: 10.1007/s00395-018-0702-1
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Mkrtchyan, GV; Üçal, M; Müllebner, A; Dumitrescu, S; Kames, M; Moldzio, R; Molcanyi, M; Schaefer, S; Weidinger, A; Schaefer, U; Hescheler, J; Duvigneau, JC; Redl, H; Bunik, VI; Kozlov, AV Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex.
BBA - Bioenergetics. 2018; 1859(9): 925-931. Doi: 10.1016/j.bbabio.2018.05.005 [OPEN ACCESS]
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2017

Grabner, GF; Zimmermann, R; Schicho, R; Taschler, U Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.
Pharmacol Ther. 2017; 175:35-46 Doi: 10.1016/j.pharmthera.2017.02.033 [OPEN ACCESS]
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Jurkin, J; Krump, C; Köffel, R; Fieber, C; Schuster, C; Brunner, PM; Borek, I; Eisenwort, G; Lim, C; Mages, J; Lang, R; Bauer, W; Mechtcheriakova, D; Meshcheryakova, A; Elbe-Bürger, A; Stingl, G; Strobl, H Human skin dendritic cell fate is differentially regulated by the monocyte identity factor Kruppel-like factor 4 during steady state and inflammation.
J Allergy Clin Immunol. 2017; 139(6):1873-1884 Doi: 10.1016/j.jaci.2016.09.018 [OPEN ACCESS]
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Li, B; Lee, C; Martin, Z; Li, X; Koike, Y; Hock, A; Zani-Ruttenstock, E; Zani, A; Pierro, A Intestinal epithelial injury induced by maternal separation is protected by hydrogen sulfide.
J Pediatr Surg. 2017; 52(1): 40-44. Doi: 10.1016/j.jpedsurg.2016.10.013
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Mangge, H; Ciardi, C; Becker, K; Strasser, B; Fuchs, D; Gostner, JM Influence of Antioxidants on Leptin Metabolism and its Role in the Pathogenesis of Obesity.
Adv Exp Med Biol. 2017; 960(2):399-413 Doi: 10.1007/978-3-319-48382-5_17
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Melvin, AJ; Warshaw, M; Compagnucci, A; Saidi, Y; Harrison, L; Turkova, A; Tudor-Williams, G; Tudor-Williams, G Hepatic, Renal, Hematologic, and Inflammatory Markers in HIV-Infected Children on Long-term Suppressive Antiretroviral Therapy.
J Pediatric Infect Dis Soc. 2017; 6(3):e109-e115-e109-e115 Doi: 10.1093/jpids/pix050 [OPEN ACCESS]
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Schrumpf, E; Jiang, X; Zeissig, S; Pollheimer, MJ; Anmarkrud, JA; Tan, C; Exley, MA; Karlsen, TH; Blumberg, RS; Melum, E The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation.
Physiol Rep. 2017; 5(4): Doi: 10.14814/phy2.13117 [OPEN ACCESS]
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Stachon, P; Heidenreich, A; Merz, J; Hilgendorf, I; Wolf, D; Willecke, F; von Garlen, S; Albrecht, P; Härdtner, C; Ehrat, N; Hoppe, N; Reinöhl, J; von Zur Mühlen, C; Bode, C; Idzko, M; Zirlik, A P2X₇ Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice.
CIRCULATION. 2017; 135(25): 2524-2533. Doi: 10.1161/CIRCULATIONAHA.117.027400
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Wolf, D; Bukosza, N; Engel, D; Poggi, M; Jehle, F; Anto Michel, N; Chen, YC; Colberg, C; Hoppe, N; Dufner, B; Boon, L; Blankenbach, H; Hilgendorf, I; von Zur Muhlen, C; Reinöhl, J; Sommer, B; Marchini, T; Febbraio, MA; Weber, C; Bode, C; Peter, K; Lutgens, E; Zirlik, A Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).
Thromb Haemost. 2017; 117(2):325-338 Doi: 10.1160/TH16-07-0553
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2016

Grün, NG; Strohmeier, K; Moreno-Viedma, V; Le Bras, M; Landlinger, C; Zeyda, K; Wanko, B; Leitner, L; Staffler, G; Zeyda, M; Stulnig, TM Peptide-based vaccination against OPN integrin binding sites does not improve cardio-metabolic disease in mice.
Immunol Lett. 2016; 179(11):85-94 Doi: 10.1016/j.imlet.2016.09.006 [OPEN ACCESS]
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Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity.
Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322 Doi: 10.1152/ajpgi.00094.2015 [OPEN ACCESS]
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Stachon, P; Geis, S; Peikert, A; Heidenreich, A; Michel, NA; Ünal, F; Hoppe, N; Dufner, B; Schulte, L; Marchini, T; Cicko, S; Ayata, K; Zech, A; Wolf, D; Hilgendorf, I; Willecke, F; Reinöhl, J; von Zur Mühlen, C; Bode, C; Idzko, M; Zirlik, A Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice.
Arterioscler Thromb Vasc Biol. 2016; 36(8):1577-1586 Doi: 10.1161/ATVBAHA.115.307397 [OPEN ACCESS]
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Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Spoerk, S; Lang-Loidolt, D Seasonal proteome changes of nasal mucus reflect perennial inflammatory response and reduced defence mechanisms and plasticity in allergic rhinitis.
J Proteomics. 2016; 133(4):153-160 Doi: 10.1016/j.jprot.2015.12.021 [OPEN ACCESS]
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Wolf, P; Byrne, SN; Limon-Flores, AY; Hoefler, G; Ullrich, SE Serotonin signalling is crucial in the induction of PUVA-induced systemic suppression of delayed-type hypersensitivity but not local apoptosis or inflammation of the skin.
Exp Dermatol. 2016; 25(7):537-543 Doi: 10.1111/exd.12990 [OPEN ACCESS]
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2015

Farzi, A; Reichmann, F; Holzer, P The homeostatic role of neuropeptide Y in immune function and its impact on mood and behaviour.
Acta Physiol (Oxf). 2015; 213(3):603-627 Doi: 10.1111/apha.12445 [OPEN ACCESS]
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Gallego-Colon, E; Sampson, RD; Sattler, S; Schneider, MD; Rosenthal, N; Tonkin, J Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction.
Mediators Inflamm. 2015; 2015: 484357 Doi: 10.1155/2015/484357 [OPEN ACCESS]
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Holzer, P Acid-sensing ion channels in gastrointestinal function.
Neuropharmacology. 2015; 94(9):72-79 Doi: 10.1016/j.neuropharm.2014.12.009 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Barghash, A; Schultheiss, CS; Lederer, E; Artl, M; Helms, V; Haybaeck, J; Kiemer, AK IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.
Cell Death Dis. 2015; 6(1):e1894-e1894 Doi: 10.1038/cddis.2015.241 [OPEN ACCESS]
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Kirsch, AH; Kirsch, A; Artinger, K; Schabhüttl, C; Goessler, W; Klymiuk, I; Gülly, C; Fritz, GA; Frank, S; Wimmer, R; Brodmann, M; Anders, HJ; Pramstaller, PP; Rosenkranz, AR; Eller, K; Eller, P Heterogeneous susceptibility for uraemic media calcification and concomitant inflammation within the arterial tree.
Nephrol Dial Transplant. 2015; 30(12):1995-2005 Doi: 10.1093/ndt/gfv265 [OPEN ACCESS]
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Landgraf, K; Rockstroh, D; Wagner, IV; Weise, S; Tauscher, R; Schwartze, JT; Löffler, D; Bühligen, U; Wojan, M; Till, H; Kratzsch, J; Kiess, W; Blüher, M; Körner, A Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children.
Diabetes. 2015; 64(4):1249-1261 Doi: 10.2337/db14-0744 [OPEN ACCESS]
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Marsche, G Lp-PLA2, plaque inflammation and lesion development vary fundamentally between different vascular sites.
J Am Heart Assoc. 2015; 4(2): Doi: 10.1161/JAHA.115.001800 [OPEN ACCESS]
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2014

Hilgendorf, I; Gerhardt, LM; Tan, TC; Winter, C; Holderried, TA; Chousterman, BG; Iwamoto, Y; Liao, R; Zirlik, A; Scherer-Crosbie, M; Hedrick, CC; Libby, P; Nahrendorf, M; Weissleder, R; Swirski, FK Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium.
CIRC RES. 2014; 114(10): 1611-1622. Doi: 10.1161/CIRCRESAHA.114.303204 [OPEN ACCESS]
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Jha, P; Knopf, A; Koefeler, H; Mueller, M; Lackner, C; Hoefler, G; Claudel, T; Trauner, M; Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).
BBA-MOL BASIS DIS. 2014; 1842(7): 959-970. Doi: 10.1016/j.bbadis.2014.02.012 [OPEN ACCESS]
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Köffel, R; Meshcheryakova, A; Warszawska, J; Hennig, A; Wagner, K; Jörgl, A; Gubi, D; Moser, D; Hladik, A; Hoffmann, U; Fischer, MB; van den Berg, W; Koenders, M; Scheinecker, C; Gesslbauer, B; Knapp, S; Strobl, H Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation.
Blood. 2014; 124(17):2713-2724 Doi: 10.1182/blood-2014-07-588178 [OPEN ACCESS]
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Koller, L; Kleber, M; Goliasch, G; Sulzgruber, P; Scharnagl, H; Silbernagel, G; Grammer, T; Delgado, G; Tomaschitz, A; Pilz, S; März, W; Niessner, A C-reactive protein predicts mortality in patients referred for coronary angiography and symptoms of heart failure with preserved ejection fraction.
Eur J Heart Fail. 2014; 16(7):758-766 Doi: 10.1002/ejhf.104 [OPEN ACCESS]
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Konradi, S; Yasmin, N; Haslwanter, D; Weber, M; Gesslbauer, B; Sixt, M; Strobl, H Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2.
Eur J Immunol. 2014; 44(2):553-560 Doi: 10.1002/eji.201343681 [OPEN ACCESS]
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Koyani, CN; Windischhofer, W; Rossmann, C; Jin, G; Kickmaier, S; Heinzel, FR; Groschner, K; Alavian-Ghavanini, A; Sattler, W; Malle, E 15-deoxy-Δ¹²,¹⁴-PGJ₂ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis.
Int J Cardiol. 2014; 173(3):472-480 Doi: 10.1016/j.ijcard.2014.03.086 [OPEN ACCESS]
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Mangge, H; Almer, G; Stelzer, I; Reininghaus, E; Prassl, R Laboratory medicine for molecular imaging of atherosclerosis.
Clin Chim Acta. 2014; 437(2):19-24 Doi: 10.1016/j.cca.2014.06.029
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