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Search Items: DOWN-REGULATION - , . hits: 75

2017

Pessentheiner, AR; Huber, K; Pelzmann, HJ; Prokesch, A; Radner, FPW; Wolinski, H; Lindroos-Christensen, J; Hoefler, G; Rülicke, T; Birner-Gruenberger, R; Bilban, M; Bogner-Strauss, JG APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
FASEB J. 2017; 31(9):4088-4103 [OPEN ACCESS]
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2016

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 [OPEN ACCESS]
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Baranyi, A; Amouzadeh-Ghadikolai, O; von Lewinski, D; Rothenhäusler, HB; Theokas, S; Robier, C; Mangge, H; Reicht, G; Hlade, P; Meinitzer, A Branched-Chain Amino Acids as New Biomarkers of Major Depression - A Novel Neurobiology of Mood Disorder.
PLoS One. 2016; 11(8):e0160542-e0160542 [OPEN ACCESS]
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Przybyl, L; Haase, N; Golic, M; Rugor, J; Solano, ME; Arck, PC; Gauster, M; Huppertz, B; Emontzpohl, C; Stoppe, C; Bernhagen, J; Leng, L; Bucala, R; Schulz, H; Heuser, A; Weedon-Fekjær, MS; Johnsen, GM; Peetz, D; Luft, FC; Staff, AC; Müller, DN; Dechend, R; Herse, F CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia.
Circ Res. 2016; 119(1):55-68 [OPEN ACCESS]
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Stradner, MH; Cheung, KP; Lasorella, A; Goldrath, AW; D'Cruz, LM Id2 regulates hyporesponsive invariant natural killer T cells.
Immunol Cell Biol. 2016; 94(7):640-645 [OPEN ACCESS]
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Verbrugge, SE; Al, M; Assaraf, YG; Kammerer, S; Chandrupatla, DM; Honeywell, R; Musters, RP; Giovannetti, E; O'Toole, T; Scheffer, GL; Krige, D; de Gruijl, TD; Niessen, HW; Lems, WF; Kramer, PA; Scheper, RJ; Cloos, J; Ossenkoppele, GJ; Peters, GJ; Jansen, G Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.
Oncotarget. 2016; 7(5):5240-5257 [OPEN ACCESS]
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2015

Alesutan, I; Voelkl, J; Stöckigt, F; Mia, S; Feger, M; Primessnig, U; Sopjani, M; Munoz, C; Borst, O; Gawaz, M; Pieske, B; Metzler, B; Heinzel, F; Schrickel, JW; Lang, F AMP-activated protein kinase α1 regulates cardiac gap junction protein connexin 43 and electrical remodeling following pressure overload.
Cell Physiol Biochem. 2015; 35(1):406-418 [OPEN ACCESS]
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Knabl, J; Hiden, U; Hüttenbrenner, R; Riedel, C; Hutter, S; Kirn, V; Günthner-Biller, M; Desoye, G; Kainer, F; Jeschke, U GDM Alters Expression of Placental Estrogen Receptor α in a Cell Type and Gender-Specific Manner.
Reprod Sci. 2015; 22(12):1488-1495
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Laszlo, V; Hoda, MA; Garay, T; Pirker, C; Ghanim, B; Klikovits, T; Dong, YW; Rozsas, A; Kenessey, I; Szirtes, I; Grusch, M; Jakopovic, M; Samarzija, M; Brcic, L; Kern, I; Rozman, A; Popper, H; Zöchbauer-Müller, S; Heller, G; Altenberger, C; Ziegler, B; Klepetko, W; Berger, W; Dome, B; Hegedus, B Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
J Pathol. 2015; 237(2):203-214
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Lerchbaum, E; Schwetz, V; Nauck, M; Völzke, H; Wallaschofski, H; Hannemann, A Lower bone turnover markers in metabolic syndrome and diabetes: the population-based Study of Health in Pomerania.
Nutr Metab Cardiovasc Dis. 2015; 25(5):458-463
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2014

Friedmacher, F; Fujiwara, N; Hofmann, AD; Takahashi, H; Gosemann, JH; Puri, P Expression of Eya1 and Six1 is decreased in distal airways of rats with experimental pulmonary hypoplasia.
J Pediatr Surg. 2014; 49(2): 301-304.
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Hofmann, A; Gosemann, JH; Takahashi, T; Friedmacher, F; Duess, JW; Puri, P Imbalance of caveolin-1 and eNOS expression in the pulmonary vasculature of experimental diaphragmatic hernia.
Birth Defects Res B Dev Reprod Toxicol. 2014; 101(4):341-346
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Paulson, KG; Tegeder, A; Willmes, C; Iyer, JG; Afanasiev, OK; Schrama, D; Koba, S; Thibodeau, R; Nagase, K; Simonson, WT; Seo, A; Koelle, DM; Madeleine, M; Bhatia, S; Nakajima, H; Sano, S; Hardwick, JS; Disis, ML; Cleary, MA; Becker, JC; Nghiem, P Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma.
Cancer Immunol Res. 2014; 2(11):1071-1079 [OPEN ACCESS]
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Takahashi, H; Friedmacher, F; Fujiwara, N; Hofmann, A; Takahashi, T; Puri, P Downregulation of p300 gene expression in airway mesenchyme of nitrofen-induced hypoplastic lungs.
Pediatr Surg Int. 2014; 30(4): 431-435.
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Walter, I; Wolfesberger, B; Miller, I; Mair, G; Burger, S; Gallè, B; Steinborn, R Human osteosarcoma cells respond to sorafenib chemotherapy by downregulation of the tumor progression factors S100A4, CXCR4 and the oncogene FOS.
Oncol Rep. 2014; 31(3):1147-1156
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Weisel, FC; Kloepping, C; Pichl, A; Sydykov, A; Kojonazarov, B; Wilhelm, J; Roth, M; Ridge, KM; Igarashi, K; Nishimura, K; Maison, W; Wackendorff, C; Klepetko, W; Jaksch, P; Ghofrani, HA; Grimminger, F; Seeger, W; Schermuly, RT; Weissmann, N; Kwapiszewska, G Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling.
Circulation. 2014; 129(14):1510-1523 [OPEN ACCESS]
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2013

Dingemann, J; Doi, T; Gosemann, JH; Ruttenstock, EM; Nakazawa, N; Puri, P Decreased expression of GATA4 in the diaphragm of nitrofen-induced congenital diaphragmatic hernia.
Birth Defects Res B Dev Reprod Toxicol. 2013; 98(2):139-143
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Duszka, K; Bogner-Strauss, JG; Hackl, H; Rieder, D; Neuhold, C; Prokesch, A; Trajanoski, Z; Krogsdam, AM Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue.
Mol Endocrinol. 2013; 27(1): 135-149. [OPEN ACCESS]
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Espe, KM; Raila, J; Henze, A; Blouin, K; Schneider, A; Schmiedeke, D; Krane, V; Pilz, S; Schweigert, FJ; Hocher, B; Wanner, C; Drechsler, C; German Diabetes and Dialysis Study Investigators Low plasma α-tocopherol concentrations and adverse clinical outcomes in diabetic hemodialysis patients.
Clin J Am Soc Nephrol. 2013; 8(3):452-458 [OPEN ACCESS]
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Kocić, J; Santibañez, JF; Krstić, A; Mojsilović, S; Ilić, V; Bugarski, D Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase.
Int J Biochem Cell Biol. 2013; 45(2): 464-475.
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Lohberger, B; Rinner, B; Stuendl, N; Kaltenegger, H; Steinecker-Frohnwieser, B; Bernhart, E; Bonyadi Rad, E; Weinberg, AM; Leithner, A; Bauer, R; Kretschmer, N Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.
PLoS One. 2013; 8(6):e66300-e66300 [OPEN ACCESS]
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Nardone, R; Höller, Y; Storti, M; Christova, M; Tezzon, F; Golaszewski, S; Trinka, E; Brigo, F Thiamine deficiency induced neurochemical, neuroanatomical, and neuropsychological alterations: a reappraisal.
ScientificWorldJournal. 2013; 2013(11):309143-309143 [OPEN ACCESS]
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Obrowsky, S; Chandak, PG; Patankar, JV; Povoden, S; Schlager, S; Kershaw, EE; Bogner-Strauss, JG; Hoefler, G; Levak-Frank, S; Kratky, D Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling.
J Lipid Res. 2013; 54(2):425-435 [OPEN ACCESS]
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Pichler, K; Loreto, C; Leonardi, R; Reuber, T; Weinberg, AM; Musumeci, G RANKL is downregulated in bone cells by physical activity (treadmill and vibration stimulation training) in rat with glucocorticoid-induced osteoporosis
HISTOL HISTOPATHOL. 2013; 28(9): 1185-1196.
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Röhr, C; Kerick, M; Fischer, A; Kühn, A; Kashofer, K; Timmermann, B; Daskalaki, A; Meinel, T; Drichel, D; Börno, ST; Nowka, A; Krobitsch, S; McHardy, AC; Kratsch, C; Becker, T; Wunderlich, A; Barmeyer, C; Viertler, C; Zatloukal, K; Wierling, C; Lehrach, H; Schweiger, MR High-throughput miRNA and mRNA sequencing of paired colorectal normal, tumor and metastasis tissues and bioinformatic modeling of miRNA-1 therapeutic applications.
PLoS One. 2013; 8(7):e67461-e67461 [OPEN ACCESS]
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Schemmer, P; Zhong, Z; Galli, U; Wheeler, MD; Xiangli, L; Bradford, BU; Conzelmann, LO; Forman, D; Boyer, J; Thurman, RG Glycine reduces platelet aggregation.
Amino Acids. 2013; 44(3):925-931 [OPEN ACCESS]
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Takahashi, H; Friedmacher, F; Fujiwara, N; Hofmann, A; Kutasy, B; Gosemann, JH; Puri, P Pulmonary FGF-18 gene expression is downregulated during the canalicular-saccular stages in nitrofen-induced hypoplastic lungs.
Pediatr Surg Int. 2013; 29(11): 1199-1203.
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Wölfler, MM; Meinhold-Heerlein, IM; Henkel, C; Rath, W; Neulen, J; Maass, N; Bräutigam, K Reduced hemopexin levels in peritoneal fluid of patients with endometriosis.
Fertil Steril. 2013; 100(3): 777-781.
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2012

Dieber-Rotheneder, M; Beganovic, S; Desoye, G; Lang, U; Cervar-Zivkovic, M Complex expression changes of the placental endothelin system in early and late onset preeclampsia, fetal growth restriction and gestational diabetes.
Life Sci. 2012; 91(13-14):710-715 [OPEN ACCESS]
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Fujiwara, N; Doi, T; Gosemann, JH; Kutasy, B; Friedmacher, F; Puri, P Smad1 and WIF1 genes are downregulated during saccular stage of lung development in the nitrofen rat model.
Pediatr Surg Int. 2012; 28(2): 189-193.
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Gosemann, JH; Doi, T; Kutasy, B; Friedmacher, F; Dingemann, J; Puri, P Alterations of peroxisome proliferator-activated receptor γ and monocyte chemoattractant protein 1 gene expression in the nitrofen-induced hypoplastic lung.
J Pediatr Surg. 2012; 47(5): 847-851.
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Kargl, J; Balenga, NA; Platzer, W; Martini, L; Whistler, JL; Waldhoer, M The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55.
Br J Pharmacol. 2012; 165(8):2611-2619 [OPEN ACCESS]
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Neumann, O; Kesselmeier, M; Geffers, R; Pellegrino, R; Radlwimmer, B; Hoffmann, K; Ehemann, V; Schemmer, P; Schirmacher, P; Lorenzo Bermejo, J; Longerich, T Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.
Hepatology. 2012; 56(5):1817-1827
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Pichler, M; Winter, E; Stotz, M; Eberhard, K; Samonigg, H; Lax, S; Hoefler, G; Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer.
Br J Cancer. 2012; 106(11):1826-1832 [OPEN ACCESS]
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Senanayake, U; Das, S; Vesely, P; Alzoughbi, W; Fröhlich, LF; Chowdhury, P; Leuschner, I; Hoefler, G; Guertl, B miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.
Carcinogenesis. 2012; 33(5):1014-1021 [OPEN ACCESS]
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2011

Bugger, H; Guzman, C; Zechner, C; Palmeri, M; Russell, KS; Russell, RR Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation.
Cancer Chemother Pharmacol. 2011; 67(6): 1381-1388. [OPEN ACCESS]
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Dingemann, J; Doi, T; Ruttenstock, EM; Puri, P Downregulation of FGFRL1 Contributes to the Development of the Diaphragmatic Defect in the Nitrofen Model of Congenital Diaphragmatic Hernia.
Eur J Pediatr Surg. 2011; 21(1):46-49
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Doi, T; Shintaku, M; Dingemann, J; Ruttenstock, E; Puri, P Downregulation of Midkine gene expression and its response to retinoic acid treatment in the nitrofen-induced hypoplastic lung.
Pediatr Surg Int. 2011; 27(2):199-204
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Lukošiūtė, A; Doi, T; Dingemann, J; Ruttenstock, EM; Puri, P Down-regulation of lung Kruppel-like factor in the nitrofen-induced hypoplastic lung.
Eur J Pediatr Surg. 2011; 21(1):38-41
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Luschnig-Schratl, P; Sturm, EM; Konya, V; Philipose, S; Marsche, G; Fröhlich, E; Samberger, C; Lang-Loidolt, D; Gattenlöhner, S; Lippe, IT; Peskar, BA; Schuligoi, R; Heinemann, A EP4 receptor stimulation down-regulates human eosinophil function.
Cell Mol Life Sci. 2011; 68(21): 3573-3587. [OPEN ACCESS]
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Roderburg, C; Urban, GW; Bettermann, K; Vucur, M; Zimmermann, H; Schmidt, S; Janssen, J; Koppe, C; Knolle, P; Castoldi, M; Tacke, F; Trautwein, C; Luedde, T Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis.
Hepatology. 2011; 53(1):209-218 [OPEN ACCESS]
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Schneider, S; Thurnher, D; Kloimstein, P; Leitner, V; Petzelbauer, P; Pammer, J; Brunner, M; Erovic, BM Expression of the Sonic hedgehog pathway in squamous cell carcinoma of the skin and the mucosa of the head and neck.
Head Neck. 2011; 33(2):244-250
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2010

Bonfig, KB; Gabler, A; Simon, UK; Luschin-Ebengreuth, N; Hatz, M; Berger, S; Muhammad, N; Zeier, J; Sinha, AK; Roitsch, T Post-Translational Derepression of Invertase Activity in Source Leaves via Down-Regulation of Invertase Inhibitor Expression Is Part of the Plant Defense Response.
Mol Plant. 2010; 3(6):1037-1048 [OPEN ACCESS]
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Dingemann, J; Doi, T; Ruttenstock, E; Puri, P Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia.
J Pediatr Surg. 2010; 45(10):1989-1994
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Moser, E; Kargl, J; Whistler, JL; Waldhoer, M; Tschische, P G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning g protein-coupled receptors.
PHARMACOLOGY. 2010; 86(1): 22-29. [OPEN ACCESS]
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Parichatikanond, W; Suthisisang, C; Dhepakson, P; Herunsalee, A Study of anti-inflammatory activities of the pure compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene expression.
Int Immunopharmacol. 2010; 10(11):1361-1373
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Ruttenstock, E; Doi, T; Dingemann, J; Puri, P Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia.
Pediatr Surg Int. 2010; 26(1): 59-63.
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Ruttenstock, E; Doi, T; Dingemann, J; Puri, P Insulin receptor is downregulated in the nitrofen-induced hypoplastic lung.
J Pediatr Surg. 2010; 45(5):948-952
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Ruttenstock, E; Doi, T; Dingemann, J; Puri, P Insulinlike growth factor receptor type 1 and type 2 are downregulated in the nitrofen-induced hypoplastic lung.
J Pediatr Surg. 2010; 45(6):1349-1353
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2009

Breitbach, K; Sun, GW; Köhler, J; Eske, K; Wongprompitak, P; Tan, G; Liu, Y; Gan, YH; Steinmetz, I Caspase-1 mediates resistance in murine melioidosis.
Infect Immun. 2009; 77(4):1589-1595 [OPEN ACCESS]
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