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Search Items: CELL CYCLE, . hits: 134

2020

Birnhuber, A; Egemnazarov, B; Biasin, V; Bonyadi Rad, E; Wygrecka, M; Olschewski, H; Kwapiszewska, G; Marsh, LM CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis.
Respir Res. 2020; 21(1): 167-167. [OPEN ACCESS]
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Göbl, C; Morris, VK; van Dam, L; Visscher, M; Polderman, PE; Hartlmüller, C; de Ruiter, H; Hora, M; Liesinger, L; Birner-Gruenberger, R; Vos, HR; Reif, B; Madl, T; Dansen, TB Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A.
Redox Biol. 2020; 28: 101316-101316. [OPEN ACCESS]
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Hoch, D; Bachbauer, M; Pöchlauer, C; Algaba-Chueca, F; Tandl, V; Novakovic, B; Megia, A; Gauster, M; Saffery, R; Glasner, A; Desoye, G; Majali-Martinez, A Maternal Obesity Alters Placental Cell Cycle Regulators in the First Trimester of Human Pregnancy: New Insights for BRCA1.
Int J Mol Sci. 2020; 21(2): [OPEN ACCESS]
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Lohberger, B; Bernhart, E; Stuendl, N; Glaenzer, D; Leithner, A; Rinner, B; Bauer, R; Kretschmer, N Periplocin mediates TRAIL-induced apoptosis and cell cycle arrest in human myxofibrosarcoma cells via the ERK/p38/JNK pathway.
Phytomedicine. 2020; 76: 153262-153262.
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2019

Brcic, L; Heidinger, M; Sever, AZ; Zacharias, M; Jakopovic, M; Fediuk, M; Maier, A; Quehenberger, F; Seiwerth, S; Popper, H Prognostic value of cyclin A2 and B1 expression in lung carcinoids.
Pathology. 2019;
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Hoch, D; Gauster, M; Hauguel-de Mouzon, S; Desoye, G Diabesity-associated oxidative and inflammatory stress signalling in the early human placenta.
Mol Aspects Med. 2019; 66(2):21-30
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Obradovic, H; Krstic, J; Trivanovic, D; Mojsilovic, S; Okic, I; Kukolj, T; Ilic, V; Jaukovic, A; Terzic, M; Bugarski, D Improving stemness and functional features of mesenchymal stem cells from Wharton's jelly of a human umbilical cord by mimicking the native, low oxygen stem cell niche.
PLACENTA. 2019; 82(3): 25-34.
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Schenk, M; Kröpfl, JM; Hörmann-Kröpfl, M; Weiss, G Endometriosis accelerates synchronization of early embryo cell divisions but does not change morphokinetic dynamics in endometriosis patients.
PLoS One. 2019; 14(8):e0220529-e0220529 [OPEN ACCESS]
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Schwarzenbacher, D; Klec, C; Pasculli, B; Cerk, S; Rinner, B; Karbiener, M; Ivan, C; Barbano, R; Ling, H; Wulf-Goldenberg, A; Stanzer, S; Rinnerthaler, G; Stoeger, H; Bauernhofer, T; Haybaeck, J; Hoefler, G; Jahn, SW; Parrella, P; Calin, GA; Pichler, M MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors.
Breast Cancer Res. 2019; 21(1): 20-20. [OPEN ACCESS]
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Shamloo, B; Usluer, S p21 in Cancer Research.
CANCERS. 2019; 11(8): [OPEN ACCESS]
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Smolle, E; Fink-Neuboeck, N; Lindenmann, J; Smolle-Juettner, F; Pichler, M The Biological and Clinical Relevance of Inhibitor of Growth (ING) Genes in Non-Small Cell Lung Cancer.
Cancers (Basel). 2019; 11(8): [OPEN ACCESS]
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2018

Bourgeois, B; Madl, T Regulation of cellular senescence via the FOXO4-p53 axis.
FEBS Lett. 2018; 592(12):2083-2097 [OPEN ACCESS]
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Durchschein, C; Hufner, A; Rinner, B; Stallinger, A; Deutsch, A; Lohberger, B; Bauer, R; Kretschmer, N Synthesis of Novel Shikonin Derivatives and Pharmacological Effects of Cyclopropylacetylshikonin on Melanoma Cells.
Molecules. 2018; 23(11): [OPEN ACCESS]
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Jahanafrooz, Z; Motamed, N; Rinner, B; Mokhtarzadeh, A; Baradaran, B Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator.
Life Sci. 2018; 213:236-247
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Kretschmer, N; Deutsch, A; Durchschein, C; Rinner, B; Stallinger, A; Higareda-Almaraz, JC; Scheideler, M; Lohberger, B; Bauer, R Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction.
Molecules. 2018; 23(11): [OPEN ACCESS]
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Krstic, J; Galhuber, M; Schulz, TJ; Schupp, M; Prokesch, A p53 as a Dichotomous Regulator of Liver Disease: The Dose Makes the Medicine.
Int J Mol Sci. 2018; 19(3): [OPEN ACCESS]
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Kukolj, T; Trivanović, D; Djordjević, IO; Mojsilović, S; Krstić, J; Obradović, H; Janković, S; Santibanez, JF; Jauković, A; Bugarski, D Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling.
J Cell Physiol. 2018; 233(1): 447-462.
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Madreiter-Sokolowski, CT; Sokolowski, AA; Waldeck-Weiermair, M; Malli, R; Graier, WF Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction.
Genes (Basel). 2018; 9(3): [OPEN ACCESS]
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Shen, P; Reineke, LC; Knutsen, E; Chen, M; Pichler, M; Ling, H; Calin, GA Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling.
Mol Oncol. 2018; 12(11): 1856-1870. [OPEN ACCESS]
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2017

Bernhart, E; Stuendl, N; Kaltenegger, H; Windpassinger, C; Donohue, N; Leithner, A; Lohberger, B Histone deacetylase inhibitors vorinostat and panobinostat induce G1 cell cycle arrest and apoptosis in multidrug resistant sarcoma cell lines.
Oncotarget. 2017; 8(44):77254-77267 [OPEN ACCESS]
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Karlsson, J; Kroneis, T; Jonasson, E; Larsson, E; Ståhlberg, A Transcriptomic Characterization of the Human Cell Cycle in Individual Unsynchronized Cells.
J Mol Biol. 2017; 429(24):3909-3924
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Khan, MA; Windpassinger, C; Ali, MZ; Zubair, M; Gul, H; Abbas, S; Khan, S; Badar, M; Mohammad, RM; Nawaz, Z Molecular genetic analysis of consanguineous families with primary microcephaly identified pathogenic variants in the ASPM gene.
J Genet. 2017; 96(2):383-387 [OPEN ACCESS]
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Peschel, I; Podmirseg, SR; Taschler, M; Duyster, J; Götze, KS; Sill, H; Nachbaur, D; Jäkel, H; Hengst, L FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27Kip1 in acute myeloid leukemia.
Haematologica. 2017; 102(8):1378-1389 [OPEN ACCESS]
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Rashed, MH; Kanlikilicer, P; Rodriguez-Aguayo, C; Pichler, M; Bayraktar, R; Bayraktar, E; Ivan, C; Filant, J; Silva, A; Aslan, B; Denizli, M; Mitra, R; Ozpolat, B; Calin, GA; Sood, AK; Abd-Ellah, MF; Helal, GK; Berestein, GL Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget. 2017; 8(12):20145-20164 [OPEN ACCESS]
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2016

Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
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Mayr, C; Wagner, A; Loeffelberger, M; Bruckner, D; Jakab, M; Berr, F; Di Fazio, P; Ocker, M; Neureiter, D; Pichler, M; Kiesslich, T The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.
Oncotarget. 2016; 7(1):745-758 [OPEN ACCESS]
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Pehserl, AM; Ress, AL; Stanzer, S; Resel, M; Karbiener, M; Stadelmeyer, E; Stiegelbauer, V; Gerger, A; Mayr, C; Scheideler, M; Hutterer, GC; Bauernhofer, T; Kiesslich, T; Pichler, M Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells.
Int J Mol Sci. 2016; 17(12): [OPEN ACCESS]
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Trierweiler, C; Hockenjos, B; Zatloukal, K; Thimme, R; Blum, HE; Wagner, EF; Hasselblatt, P The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice.
Cell Death Differ. 2016; 23(4):576-582 [OPEN ACCESS]
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2015

Bochis, OV; Irimie, A; Pichler, M; Berindan-Neagoe, I The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer.
J Gastrointestin Liver Dis. 2015; 24(2):225-234 [OPEN ACCESS]
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Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
Mol Cancer. 2015; 14(8):4-4 [OPEN ACCESS]
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Froehlich, EV; Rinner, B; Deutsch, AJ; Meditz, K; Knausz, H; Troppan, K; Scheipl, S; Wibmer, C; Leithner, A; Liegl, B; Lohberger, B Examination of survivin expression in 50 chordoma specimens--A histological and in vitro study.
J Orthop Res. 2015; 33(5):771-778 [OPEN ACCESS]
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Juntermanns, B; Sydor, S; Kaiser, GM; Jaradat, D; Mertens, JC; Sotiropoulos, GC; Swoboda, S; Neuhaus, JP; Meng, W; Mathé, Z; Baba, HA; Canbay, A; Paul, A; Fingas, CD Polo-like kinase 3 is associated with improved overall survival in cholangiocarcinoma.
Liver Int. 2015; 35(11):2448-2457
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Krstić, J; Trivanović, D; Mojsilović, S; Santibanez, JF Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression.
Oxid Med Cell Longev. 2015; 2015(3): 654594-654594. [OPEN ACCESS]
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Lohberger, B; Kretschmer, N; Bernhart, E; Rinner, B; Stuendl, N; Kaltenegger, H; Kahl, S; Bauer, R; Leithner, A 25-O-acetyl-23,24-dihydro-cucurbitacin F induces cell cycle G2/M arrest and apoptosis in human soft tissue sarcoma cells.
J Ethnopharmacol. 2015; 164(36):265-272
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Lohberger, B; Leithner, A; Stuendl, N; Kaltenegger, H; Kullich, W; Steinecker-Frohnwieser, B Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation.
BMC Cancer. 2015; 15(3):891-891 [OPEN ACCESS]
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Mayr, C; Wagner, A; Neureiter, D; Pichler, M; Jakab, M; Illig, R; Berr, F; Kiesslich, T The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cells.
BMC Complement Altern Med. 2015; 15(6):194-194 [OPEN ACCESS]
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Pozo, K; Hillmann, A; Augustyn, A; Plattner, F; Hai, T; Singh, T; Ramezani, S; Sun, X; Pfragner, R; Minna, JD; Cote, GJ; Chen, H; Bibb, JA; Nwariaku, FE Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis.
Oncotarget. 2015; 6(14):12080-12093 [OPEN ACCESS]
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Smolle, MA; Pichler, M; Haybaeck, J; Gerger, A Genetic markers of recurrence in colorectal cancer.
Pharmacogenomics. 2015; 16(11):1315-1328
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Wenzl, K; Troppan, K; Neumeister, P; Deutsch, AJ The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.
Curr Drug Targets. 2015; 16(1):38-46
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Zhao, Q; Assimopoulou, AN; Klauck, SM; Damianakos, H; Chinou, I; Kretschmer, N; Rios, JL; Papageorgiou, VP; Bauer, R; Efferth, T Inhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells.
Oncotarget. 2015; 6(36):38934-38951 [OPEN ACCESS]
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2014

Absenger, G; Benhaim, L; Szkandera, J; Zhang, W; Yang, D; Labonte, MJ; Pichler, M; Stotz, M; Samonigg, H; Renner, W; Gerger, A; Lenz, HJ The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy.
Pharmacogenomics J. 2014; 14(2):130-134
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Bálint, Z; Zabini, D; Konya, V; Nagaraj, C; Végh, AG; Váró, G; Wilhelm, I; Fazakas, C; Krizbai, IA; Heinemann, A; Olschewski, H; Olschewski, A Double-stranded RNA attenuates the barrier function of human pulmonary artery endothelial cells.
PLoS One. 2014; 8(6):e63776-e63776 [OPEN ACCESS]
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Bernhart, E; Damm, S; Heffeter, P; Wintersperger, A; Asslaber, M; Frank, S; Hammer, A; Strohmaier, H; DeVaney, T; Mrfka, M; Eder, H; Windpassinger, C; Ireson, CR; Mischel, PS; Berger, W; Sattler, W Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.
Neuro Oncol. 2014; 16(7):933-945 [OPEN ACCESS]
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Biasin, V; Chwalek, K; Wilhelm, J; Best, J; Marsh, LM; Ghanim, B; Klepetko, W; Fink, L; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
Int J Biochem Cell Biol. 2014; 54(3):137-148
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Fric, J; Lim, CX; Mertes, A; Lee, BT; Viganò, E; Chen, J; Zolezzi, F; Poidinger, M; Larbi, A; Strobl, H; Zelante, T; Ricciardi-Castagnoli, P Calcium and calcineurin-NFAT signaling regulate granulocyte-monocyte progenitor cell cycle via Flt3-L.
Stem Cells. 2014; 32(12):3232-3244 [OPEN ACCESS]
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Khan, MA; Rupp, VM; Orpinell, M; Hussain, MS; Altmüller, J; Steinmetz, MO; Enzinger, C; Thiele, H; Höhne, W; Nürnberg, G; Baig, SM; Ansar, M; Nürnberg, P; Vincent, JB; Speicher, MR; Gönczy, P; Windpassinger, C A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family.
Hum Mol Genet. 2014; 23(22):5940-5949 [OPEN ACCESS]
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Kiesslich, T; Mayr, C; Wachter, J; Bach, D; Fuereder, J; Wagner, A; Alinger, B; Pichler, M; Di Fazio, P; Ocker, M; Berr, F; Neureiter, D Activated hedgehog pathway is a potential target for pharmacological intervention in biliary tract cancer.
Mol Cell Biochem. 2014; 396(1-2):257-268
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Schelch, K; Hoda, MA; Klikovits, T; Münzker, J; Ghanim, B; Wagner, C; Garay, T; Laszlo, V; Setinek, U; Dome, B; Filipits, M; Pirker, C; Heffeter, P; Selzer, E; Tovari, J; Torok, S; Kenessey, I; Holzmann, K; Grasl-Kraupp, B; Marian, B; Klepetko, W; Berger, W; Hegedus, B; Grusch, M Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.
Am J Respir Crit Care Med. 2014; 190(7):763-772
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Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Nojima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Heitzer, E; Geigl, JB; Windpassinger, C; Hoefler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Nat Commun. 2014; 5(10):5191-5191 [OPEN ACCESS]
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Vincent, K; Pichler, M; Lee, GW; Ling, H MicroRNAs, genomic instability and cancer.
Int J Mol Sci. 2014; 15(8):14475-14491 [OPEN ACCESS]
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