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Search Items: CELL PROLIFERATION - , . hits: 175

2017

Artinger, K; Kirsch, AH; Aringer, I; Moschovaki-Filippidou, F; Eller, P; Rosenkranz, AR; Eller, K Innate and adaptive immunity in experimental glomerulonephritis: a pathfinder tale.
Pediatr Nephrol. 2017; 32(6):943-947 [OPEN ACCESS]
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Cossarizza, A; Chang, HD; Radbruch, A; Akdis, M; Andrä, I; Annunziato, F; Bacher, P; Barnaba, V; Battistini, L; Bauer, WM; Baumgart, S; Becher, B; Beisker, W; Berek, C; Blanco, A; Borsellino, G; Boulais, PE; Brinkman, RR; Büscher, M; Busch, DH; Bushnell, TP; Cao, X; Cavani, A; Chattopadhyay, PK; Cheng, Q; Chow, S; Clerici, M; Cooke, A; Cosma, A; Cosmi, L; Cumano, A; Dang, VD; Davies, D; De Biasi, S; Del Zotto, G; Della Bella, S; Dellabona, P; Deniz, G; Dessing, M; Diefenbach, A; Di Santo, J; Dieli, F; Dolf, A; Donnenberg, VS; Dörner, T; Ehrhardt, GRA; Endl, E; Engel, P; Engelhardt, B; Esser, C; Everts, B; Dreher, A; Falk, CS; Fehniger, TA; Filby, A; Fillatreau, S; Follo, M; Förster, I; Foster, J; Foulds, GA; Frenette, PS; Galbraith, D; Garbi, N; García-Godoy, MD; Geginat, J; Ghoreschi, K; Gibellini, L; Goettlinger, C; Goodyear, CS; Gori, A; Grogan, J; Gross, M; Grützkau, A; Grummitt, D; Hahn, J; Hammer, Q; Hauser, AE; Haviland, DL; Hedley, D; Herrera, G; Herrmann, M; Hiepe, F; Holland, T; Hombrink, P; Houston, JP; Hoyer, BF; Huang, B; Hunter, CA; Iannone, A; Jäck, HM; Jávega, B; Jonjic, S; Juelke, K; Jung, S; Kaiser, T; Kalina, T; Keller, B; Khan, S; Kienhöfer, D; Kroneis, T; Kunkel, D; Kurts, C; Kvistborg, P; Lannigan, J; Lantz, O; Larbi, A; LeibundGut-Landmann, S; Leipold, MD; Levings, MK; Litwin, V; Liu, Y; Lohoff, M; Lombardi, G; Lopez, L; Lovett-Racke, A; Lubberts, E; Ludewig, B; Lugli, E; Maecker, HT; Martrus, G; Matarese, G; Maueröder, C; McGrath, M; McInnes, I; Mei, HE; Melchers, F; Melzer, S; Mielenz, D; Mills, K; Mirrer, D; Mjösberg, J; Moore, J; Moran, B; Moretta, A; Moretta, L; Mosmann, TR; Müller, S; Müller, W; Münz, C; Multhoff, G; Munoz, LE; Murphy, KM; Nakayama, T; Nasi, M; Neudörfl, C; Nolan, J; Nourshargh, S; O'Connor, JE; Ouyang, W; Oxenius, A; Palankar, R; Panse, I; Peterson, P; Peth, C; Petriz, J; Philips, D; Pickl, W; Piconese, S; Pinti, M; Pockley, AG; Podolska, MJ; Pucillo, C; Quataert, SA; Radstake, TRDJ; Rajwa, B; Rebhahn, JA; Recktenwald, D; Remmerswaal, EBM; Rezvani, K; Rico, LG; Robinson, JP; Romagnani, C; Rubartelli, A; Ruckert, B; Ruland, J; Sakaguchi, S; Sala-de-Oyanguren, F; Samstag, Y; Sanderson, S; Sawitzki, B; Scheffold, A; Schiemann, M; Schildberg, F; Schimisky, E; Schmid, SA; Schmitt, S; Schober, K; Schüler, T; Schulz, AR; Schumacher, T; Scotta, C; Shankey, TV; Shemer, A; Simon, AK; Spidlen, J; Stall, AM; Stark, R; Stehle, C; Stein, M; Steinmetz, T; Stockinger, H; Takahama, Y; Tarnok, A; Tian, Z; Toldi, G; Tornack, J; Traggiai, E; Trotter, J; Ulrich, H; van der Braber, M; van Lier, RAW; Veldhoen, M; Vento-Asturias, S; Vieira, P; Voehringer, D; Volk, HD; von Volkmann, K; Waisman, A; Walker, R; Ward, MD; Warnatz, K; Warth, S; Watson, JV; Watzl, C; Wegener, L; Wiedemann, A; Wienands, J; Willimsky, G; Wing, J; Wurst, P; Yu, L; Yue, A; Zhang, Q; Zhao, Y; Ziegler, S; Zimmermann, J Guidelines for the use of flow cytometry and cell sorting in immunological studies.
Eur J Immunol. 2017; 47(10):1584-1797 [OPEN ACCESS]
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Duchene, J; Novitzky-Basso, I; Thiriot, A; Casanova-Acebes, M; Bianchini, M; Etheridge, SL; Hub, E; Nitz, K; Artinger, K; Eller, K; Caamaño, J; Rülicke, T; Moss, P; Megens, RTA; von Andrian, UH; Hidalgo, A; Weber, C; Rot, A Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
Nat Immunol. 2017; 18(7):753-761 [OPEN ACCESS]
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Edlinger, L; Berger-Becvar, A; Menzl, I; Hoermann, G; Greiner, G; Grundschober, E; Bago-Horvath, Z; Al-Zoughbi, W; Hoefler, G; Brostjan, C; Gille, L; Moriggl, R; Spittler, A; Sexl, V; Hoelbl-Kovacic, A Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1.
Br J Haematol. 2017; 179(2):229-241 [OPEN ACCESS]
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Mayr, C; Ocker, M; Ritter, M; Pichler, M; Neureiter, D; Kiesslich, T Biliary tract cancer stem cells - translational options and challenges.
World J Gastroenterol. 2017; 23(14):2470-2482 [OPEN ACCESS]
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Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
PLoS One. 2017; 12(11):e0187814-e0187814 [OPEN ACCESS]
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Richtig, G; Ehall, B; Richtig, E; Aigelsreiter, A; Gutschner, T; Pichler, M Function and Clinical Implications of Long Non-Coding RNAs in Melanoma.
Int J Mol Sci. 2017; 18(4): [OPEN ACCESS]
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Rigoutsos, I; Lee, SK; Nam, SY; Anfossi, S; Pasculli, B; Pichler, M; Jing, Y; Rodriguez-Aguayo, C; Telonis, AG; Rossi, S; Ivan, C; Catela Ivkovic, T; Fabris, L; Clark, PM; Ling, H; Shimizu, M; Redis, RS; Shah, MY; Zhang, X; Okugawa, Y; Jung, EJ; Tsirigos, A; Huang, L; Ferdin, J; Gafà, R; Spizzo, R; Nicoloso, MS; Paranjape, AN; Shariati, M; Tiron, A; Yeh, JJ; Teruel-Montoya, R; Xiao, L; Melo, SA; Menter, D; Jiang, ZQ; Flores, ER; Negrini, M; Goel, A; Bar-Eli, M; Mani, SA; Liu, CG; Lopez-Berestein, G; Berindan-Neagoe, I; Esteller, M; Kopetz, S; Lanza, G; Calin, GA N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration.
Genome Biol. 2017; 18(1):98-98 [OPEN ACCESS]
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Sharp, TE; Schena, GJ; Hobby, AR; Starosta, T; Berretta, RM; Wallner, M; Borghetti, G; Gross, P; Yu, D; Johnson, J; Feldsott, E; Trappanese, DM; Toib, A; Rabinowitz, JE; George, JC; Kubo, H; Mohsin, S; Houser, SR Cortical Bone Stem Cell Therapy Preserves Cardiac Structure and Function After Myocardial Infarction.
Circ Res. 2017; 121(11):1263-1278 [OPEN ACCESS]
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Wagner, G; Lindroos-Christensen, J; Einwallner, E; Husa, J; Zapf, TC; Lipp, K; Rauscher, S; Gröger, M; Spittler, A; Loewe, R; Gruber, F; Duvigneau, JC; Mohr, T; Sutterlüty-Fall, H; Klinglmüller, F; Prager, G; Huppertz, B; Yun, J; Wagner, O; Esterbauer, H; Bilban, M HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.
Sci Rep. 2017; 7(4):40881-40881 [OPEN ACCESS]
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Windpassinger, C; Piard, J; Bonnard, C; Alfadhel, M; Lim, S; Bisteau, X; Blouin, S; Ali, NB; Ng, AYJ; Lu, H; Tohari, S; Talib, SZA; van Hul, N; Caldez, MJ; Van Maldergem, L; Yigit, G; Kayserili, H; Youssef, SA; Coppola, V; de Bruin, A; Tessarollo, L; Choi, H; Rupp, V; Roetzer, K; Roschger, P; Klaushofer, K; Altmüller, J; Roy, S; Venkatesh, B; Ganger, R; Grill, F; Ben Chehida, F; Wollnik, B; Altunoglu, U; Al Kaissi, A; Reversade, B; Kaldis, P CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
Am J Hum Genet. 2017; 101(3):391-403 [OPEN ACCESS]
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Zadora, J; Singh, M; Herse, F; Przybyl, L; Haase, N; Golic, M; Yung, HW; Huppertz, B; Cartwright, JE; Whitley, G; Johnsen, GM; Levi, G; Isbruch, A; Schulz, H; Luft, FC; Müller, DN; Staff, AC; Hurst, LD; Dechend, R; Izsvák, Z Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker.
CIRCULATION. 2017; 136(19): 1824-1839. [OPEN ACCESS]
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2016

Calamaro, P; Cerroni, L Intralymphatic Proliferation of T-cell Lymphoid Blasts in the Setting of Hidradenitis Suppurativa.
Am J Dermatopathol. 2016; 38(7):536-540 (- Case Report)
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Eder, C; Schenk, S; Trifinopoulos, J; Külekci, B; Kienzl, M; Schildböck, S; Ogon, M Does intrawound application of vancomycin influence bone healing in spinal surgery?
Eur Spine J. 2016; 25(4): 1021-1028.
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Fröhlich, E Cellular elimination of nanoparticles.
Environ Toxicol Pharmacol. 2016; 46(11):90-94
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Gellner, V; Tomazic, PV; Lohberger, B; Meditz, K; Heitzer, E; Mokry, M; Koele, W; Leithner, A; Liegl-Atzwanger, B; Rinner, B Establishment of clival chordoma cell line MUG-CC1 and lymphoblastoid cells as a model for potential new treatment strategies.
Sci Rep. 2016; 6(7):24195-24195 [OPEN ACCESS]
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Gross, P; Honnorat, N; Varol, E; Wallner, M; Trappanese, DM; Sharp, TE; Starosta, T; Duran, JM; Koller, S; Davatzikos, C; Houser, SR Nuquantus: Machine learning software for the characterization and quantification of cell nuclei in complex immunofluorescent tissue images.
Sci Rep. 2016; 6(7):23431-23431 [OPEN ACCESS]
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Hatzl, S; Geiger, O; Kuepper, MK; Caraffini, V; Seime, T; Furlan, T; Nussbaumer, E; Wieser, R; Pichler, M; Scheideler, M; Nowek, K; Jongen-Lavrencic, M; Quehenberger, F; Wölfler, A; Troppmair, J; Sill, H; Zebisch, A Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.
Cancer Res. 2016; 76(12):3644-3654 [OPEN ACCESS]
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Jeanquartier, F; Jean-Quartier, C; Cemernek, D; Holzinger, A In silico modeling for tumor growth visualization.
BMC Syst Biol. 2016; 10(1):59-59 [OPEN ACCESS]
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Kluk, J; Kai, A; Koch, D; Taibjee, SM; O'Connor, S; Persic, M; Morris, S; Whittaker, S; Cerroni, L; Kempf, W; Petrella, T; Robson, A Indolent CD8-positive lymphoid proliferation of acral sites: three further cases of a rare entity and an update on a unique patient.
J Cutan Pathol. 2016; 43(2):125-136 (- Case Report)
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Leithner, K; Hirschmugl, B; Li, Y; Tang, B; Papp, R; Nagaraj, C; Stacher, E; Stiegler, P; Lindenmann, J; Olschewski, A; Olschewski, H; Hrzenjak, A TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers.
PLoS One. 2016; 11(6):e0157453-e0157453 [OPEN ACCESS]
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Rasoulzadeh, Z; Ghods, R; Kazemi, T; Mirzadegan, E; Ghaffari-Tabrizi-Wizsy, N; Rezania, S; Kazemnejad, S; Arefi, S; Ghasemi, J; Vafaei, S; Mahmoudi, AR; Zarnani, AH Placental Kisspeptins Differentially Modulate Vital Parameters of Estrogen Receptor-Positive and -Negative Breast Cancer Cells.
PLoS One. 2016; 11(4):e0153684-e0153684 [OPEN ACCESS]
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Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628 [OPEN ACCESS]
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Tardelli, M; Zeyda, K; Moreno-Viedma, V; Wanko, B; Grün, NG; Staffler, G; Zeyda, M; Stulnig, TM Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity.
Mol Metab. 2016; 5(11):1131-1137 [OPEN ACCESS]
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Vieyra-Garcia, PA; Wei, T; Naym, DG; Fredholm, S; Fink-Puches, R; Cerroni, L; Odum, N; O'Malley, JT; Gniadecki, R; Wolf, P STAT3/5-Dependent IL9 Overexpression Contributes to Neoplastic Cell Survival in Mycosis Fungoides.
Clin Cancer Res. 2016; 22(13):3328-3339 [OPEN ACCESS]
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Yang, Y; Liu, Y; He, JC; Wang, JM; Schemmer, P; Ma, CQ; Qian, YW; Yao, W; Zhang, J; Qi, WP; Fu, Y; Feng, W; Yang, T 14-3-3ζ and aPKC-ι synergistically facilitate epithelial-mesenchymal transition of cholangiocarcinoma via GSK-3β/Snail signaling pathway.
Oncotarget. 2016; 7(34):55191-55210 [OPEN ACCESS]
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2015

Chen, Y; Guldiken, N; Spurny, M; Mohammed, HH; Haybaeck, J; Pollheimer, MJ; Fickert, P; Gassler, N; Jeon, MK; Trautwein, C; Strnad, P Loss of keratin 19 favours the development of cholestatic liver disease through decreased ductular reaction.
J Pathol. 2015; 237(3):343-354
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Didiasova, M; Zakrzewicz, D; Magdolen, V; Nagaraj, C; Bálint, Z; Rohde, M; Preissner, KT; Wygrecka, M STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.
J Biol Chem. 2015; 290(19):11983-11999 [OPEN ACCESS]
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Gregory, AD; Kliment, CR; Metz, HE; Kim, KH; Kargl, J; Agostini, BA; Crum, LT; Oczypok, EA; Oury, TA; Houghton, AM Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.
J Leukoc Biol. 2015; 98(2): 143-152. [OPEN ACCESS]
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Houben, R; Angermeyer, S; Haferkamp, S; Aue, A; Goebeler, M; Schrama, D; Hesbacher, S Characterization of functional domains in the Merkel cell polyoma virus Large T antigen.
Int J Cancer. 2015; 136(5):E290-E300 [OPEN ACCESS]
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Ketterl, N; Brachtl, G; Schuh, C; Bieback, K; Schallmoser, K; Reinisch, A; Strunk, D A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance.
Stem Cell Res Ther. 2015; 6(2): 236-236. [OPEN ACCESS]
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Leitner, L; Jürets, A; Itariu, BK; Keck, M; Prager, G; Langer, F; Grablowitz, V; Zeyda, M; Stulnig, TM Osteopontin promotes aromatase expression and estradiol production in human adipocytes.
Breast Cancer Res Treat. 2015; 154(1):63-69
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Schwarzenbacher, D; Stiegelbauer, V; Deutsch, A; Ress, AL; Aigelsreiter, A; Schauer, S; Wagner, K; Langsenlehner, T; Resel, M; Gerger, A; Ling, H; Ivan, C; Calin, GA; Hoefler, G; Rinner, B; Pichler, M Low spinophilin expression enhances aggressive biological behavior of breast cancer.
Oncotarget. 2015; 6(13):11191-11202 [OPEN ACCESS]
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Trivanović, D; Jauković, A; Popović, B; Krstić, J; Mojsilović, S; Okić-Djordjević, I; Kukolj, T; Obradović, H; Santibanez, JF; Bugarski, D Mesenchymal stem cells of different origin: Comparative evaluation of proliferative capacity, telomere length and pluripotency marker expression.
Life Sci. 2015; 141(3): 61-73.
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Weinberger, J; Jimenez-Heredia, R; Schaller, S; Suessner, S; Sunzenauer, J; Reindl-Schwaighofer, R; Weiss, R; Winkler, S; Gabriel, C; Danzer, M; Oberbauer, R Immune Repertoire Profiling Reveals that Clonally Expanded B and T Cells Infiltrating Diseased Human Kidneys Can Also Be Tracked in Blood.
PLoS One. 2015; 10(11):e0143125-e0143125 [OPEN ACCESS]
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Wiesner, T; Lee, W; Obenauf, AC; Ran, L; Murali, R; Zhang, QF; Wong, EW; Hu, W; Scott, SN; Shah, RH; Landa, I; Button, J; Lailler, N; Sboner, A; Gao, D; Murphy, DA; Cao, Z; Shukla, S; Hollmann, TJ; Wang, L; Borsu, L; Merghoub, T; Schwartz, GK; Postow, MA; Ariyan, CE; Fagin, JA; Zheng, D; Ladanyi, M; Busam, KJ; Berger, MF; Chen, Y; Chi, P Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature. 2015; 526(7573):453-457 [OPEN ACCESS]
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2014

Biasin, V; Chwalek, K; Wilhelm, J; Best, J; Marsh, LM; Ghanim, B; Klepetko, W; Fink, L; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
Int J Biochem Cell Biol. 2014; 54(3):137-148
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D'Cruz, LM; Stradner, MH; Yang, CY; Goldrath, AW E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation.
J Immunol. 2014; 192(5):2227-2236 [OPEN ACCESS]
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Dorronsoro, A; Ferrin, I; Salcedo, JM; Jakobsson, E; Fernández-Rueda, J; Lang, V; Sepulveda, P; Fechter, K; Pennington, D; Trigueros, C Human mesenchymal stromal cells modulate T-cell responses through TNF-α-mediated activation of NF-κB.
Eur J Immunol. 2014; 44(2):480-488 [OPEN ACCESS]
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Flecken, T; Schmidt, N; Hild, S; Gostick, E; Drognitz, O; Zeiser, R; Schemmer, P; Bruns, H; Eiermann, T; Price, DA; Blum, HE; Neumann-Haefelin, C; Thimme, R Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma.
Hepatology. 2014; 59(4):1415-1426 [OPEN ACCESS]
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García-Rodríguez, JL; Barbier-Torres, L; Fernández-Álvarez, S; Gutiérrez-de Juan, V; Monte, MJ; Halilbasic, E; Herranz, D; Álvarez, L; Aspichueta, P; Marín, JJ; Trauner, M; Mato, JM; Serrano, M; Beraza, N; Martínez-Chantar, ML SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
Hepatology. 2014; 59(5):1972-1983 [OPEN ACCESS]
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Ghasemi, A; Zarnani, AH; Ghoodjani, A; Rezania, S; Salari, MH; Jeddi-Tehrani, M Identification of a new immunogenic candidate conferring protection against Brucella melitensis infection in mice.
Mol Immunol. 2014; 62(1):142-149
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Heiduschka, G; Lill, C; Schneider, S; Seemann, R; Kornek, G; Schmid, R; Kotowski, U; Thurnher, D The effect of cilengitide in combination with irradiation and chemotherapy in head and neck squamous cell carcinoma cell lines.
Strahlenther Onkol. 2014; 190(5): 472-479.
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Kröpfl, JM; Stelzer, I; Mangge, H; Pekovits, K; Fuchs, R; Allard, N; Schinagl, L; Hofmann, P; Dohr, G; Wallner-Liebmann, S; Domej, W; Müller, W Exercise-induced norepinephrine decreases circulating hematopoietic stem and progenitor cell colony-forming capacity.
PLoS One. 2014; 9(9):e106120-e106120 [OPEN ACCESS]
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Larre Borges, A; Zalaudek, I; Longo, C; Dufrechou, L; Argenziano, G; Lallas, A; Piana, S; Moscarella, E Melanocytic nevi with special features: clinical-dermoscopic and reflectance confocal microscopic-findings.
J Eur Acad Dermatol Venereol. 2014; 28(7):833-845
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McFarlane, RJ; Feichtinger, J; Larcombe, L Cancer germline gene activation: friend or foe?
Cell Cycle. 2014; 13(14): 2151-2152. [OPEN ACCESS]
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Mlecnik, B; Bindea, G; Angell, HK; Sasso, MS; Obenauf, AC; Fredriksen, T; Lafontaine, L; Bilocq, AM; Kirilovsky, A; Tosolini, M; Waldner, M; Berger, A; Fridman, WH; Rafii, A; Valge-Archer, V; Pagès, F; Speicher, MR; Galon, J Functional network pipeline reveals genetic determinants associated with in situ lymphocyte proliferation and survival of cancer patients.
Sci Transl Med. 2014; 6(228):228ra37-228ra37 [OPEN ACCESS]
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Pellacani, G; De Pace, B; Reggiani, C; Cesinaro, AM; Argenziano, G; Zalaudek, I; Soyer, HP; Longo, C Distinct melanoma types based on reflectance confocal microscopy.
Exp Dermatol. 2014; 23(6):414-418
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Pellacani, G; Scope, A; Farnetani, F; Casaretta, G; Zalaudek, I; Moscarella, E; Casari, A; Cesinaro, AM; Argenziano, G; Longo, C Towards an in vivo morphologic classification of melanocytic nevi.
J Eur Acad Dermatol Venereol. 2014; 28(7):864-872
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Rong, Z; Wang, M; Hu, Z; Stradner, M; Zhu, S; Kong, H; Yi, H; Goldrath, A; Yang, YG; Xu, Y; Fu, X An effective approach to prevent immune rejection of human ESC-derived allografts.
Cell Stem Cell. 2014; 14(1):121-130 [OPEN ACCESS]
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