Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: TARGETED THERAPIES, . Treffer: 56

2020

Kaemmerer, H; Gorenflo, M; Huscher, D; Pittrow, D; Apitz, C; Baumgartner, H; Berger, F; Bruch, L; Brunnemer, E; Budts, W; Claussen, M; Coghlan, G; Dähnert, I; D'Alto, M; Delcroix, M; Distler, O; Dittrich, S; Dumitrescu, D; Ewert, R; Faehling, M; Germund, I; Ghofrani, HA; Grohé, C; Grossekreymborg, K; Halank, M; Hansmann, G; Harzheim, D; Nemes, A; Havasi, K; Held, M; Hoeper, MM; Hofbeck, M; Hohenfrost-Schmidt, W; Jurevičienė, E; Gumbienè, L; Kabitz, HJ; Klose, H; Köhler, T; Konstantinides, S; Köestenberger, M; Kozlik-Feldmann, R; Kramer, HH; Kropf-Sanchen, C; Lammers, A; Lange, T; Meyn, P; Miera, O; Milger-Kneidinger, K; Neidenbach, R; Neurohr, C; Opitz, C; Perings, C; Remppis, BA; Riemekasten, G; Scelsi, L; Scholtz, W; Simkova, I; Skowasch, D; Skride, A; Stähler, G; Stiller, B; Tsangaris, I; Vizza, CD; Vonk Noordegraaf, A; Wilkens, H; Wirtz, H; Diller, GP; Grünig, E; Rosenkranz, S Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry.
J Clin Med. 2020; 9(5): [OPEN ACCESS]
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Mangge, H; Prüller, F; Schnedl, W; Renner, W; Almer, G Beyond Macrophages and T Cells: B Cells and Immunoglobulins Determine the Fate of the Atherosclerotic Plaque.
Int J Mol Sci. 2020; 21(11): [OPEN ACCESS]
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2019

Legat, FJ Is there still a role for UV therapy in itch treatment?
Exp Dermatol. 2019; 28(12):1432-1438
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Scheipl, S; Liegl-Atzwanger, B; Szkandera, J; Rinner, B; Viertler, C; Friesenbichler, J; Bergovec, M; Leithner, A [Is there a magic bullet for sarcomas? : Personalised treatment for maligant tumours of bone and soft tissue].
Orthopade. 2019; 48(9): 776-783. [OPEN ACCESS]
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Schumacher, D; Andrieux, G; Boehnke, K; Keil, M; Silvestri, A; Silvestrov, M; Keilholz, U; Haybaeck, J; Erdmann, G; Sachse, C; Templin, M; Hoffmann, J; Boerries, M; Schäfer, R; Regenbrecht, CRA Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.
PLoS Genet. 2019; 15(3):e1008076-e1008076 [OPEN ACCESS]
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Seeboeck, R; Sarne, V; Haybaeck, J Current Coverage of the mTOR Pathway by Next-Generation Sequencing Oncology Panels.
Int J Mol Sci. 2019; 20(3): [OPEN ACCESS]
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Trüeb, RM; Jolliffe, VML; Régnier, AF; Dutra Rezende, H; Vañó-Galván, S; Kopera, D; Ioannides, D; Gavazzoni Dias, MFR; Macpherson, M; Gadzhigoroeva, A; Ovcharenko, J; Lee, WS; Murugusundram, S; Kurata, S; Chang, M; Tanglertsampan, C Precision Medicine and the Practice of Trichiatry: Adapting the Concept.
SKIN APPENDAGE DISOR. 2019; 5(6): 338-343. [OPEN ACCESS]
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2018

Apostolidis, L; Pfeiffenberger, J; Gotthardt, D; Radeleff, B; Mehrabi, A; Schemmer, P; Jager, D; Schirmacher, P; Stremmel, W; Schulze-Bergkamen, H; Springfeld, C; Weiss, KH Survival of Hepatocellular Carcinoma Patients Treated with Sorafenib beyond Progression
GASTROINTEST TUMORS. 2018; 5(1-2): 38-46. [OPEN ACCESS]
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Belic, J; Graf, R; Bauernhofer, T; Cherkas, Y; Ulz, P; Waldispuehl-Geigl, J; Perakis, S; Gormley, M; Patel, J; Li, W; Geigl, JB; Smirnov, D; Heitzer, E; Gross, M; Speicher, MR Genomic alterations in plasma DNA from patients with metastasized prostate cancer receiving abiraterone or enzalutamide.
Int J Cancer. 2018; 143(5): 1236-1248. [OPEN ACCESS]
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Berger, M; Richtig, G; Kashofer, K; Aigelsreiter, A; Richtig, E The window of opportunities for targeted therapy in BRAFwt/NRASwt/KITwt melanoma: biology and clinical implications of fusion proteins and other mutations.
G Ital Dermatol Venereol. 2018; 153(3): 349-360. [OPEN ACCESS]
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Krug, S; Abbassi, R; Griesmann, H; Sipos, B; Wiese, D; Rexin, P; Blank, A; Perren, A; Haybaeck, J; Hüttelmaier, S; Rinke, A; Gress, TM; Michl, P Therapeutic Targeting of Tumor-Associated Macrophages in Pancreatic Neuroendocrine Tumors.
Int J Cancer. 2018; [OPEN ACCESS]
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Zboray, K; Mohrherr, J; Stiedl, P; Pranz, K; Wandruszka, L; Grabner, B; Eferl, R; Moriggl, R; Stoiber, D; Sakamoto, K; Wagner, KU; Popper, H; Casanova, E; Moll, HP AKT3 drives adenoid cystic carcinoma development in salivary glands.
Cancer Med. 2018; 7(2):445-453 [OPEN ACCESS]
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2017

Artinger, K; Kirsch, AH; Aringer, I; Moschovaki-Filippidou, F; Eller, P; Rosenkranz, AR; Eller, K Innate and adaptive immunity in experimental glomerulonephritis: a pathfinder tale.
Pediatr Nephrol. 2017; 32(6):943-947 [OPEN ACCESS]
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Bayraktar, R; Pichler, M; Kanlikilicer, P; Ivan, C; Bayraktar, E; Kahraman, N; Aslan, B; Oguztuzun, S; Ulasli, M; Arslan, A; Calin, G; Lopez-Berestein, G; Ozpolat, B MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase.
Oncotarget. 2017; 8(7):11641-11658 [OPEN ACCESS]
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Chao, MP; Gentles, AJ; Chatterjee, S; Lan, F; Reinisch, A; Corces, MR; Xavy, S; Shen, J; Haag, D; Chanda, S; Sinha, R; Morganti, RM; Nishimura, T; Ameen, M; Wu, H; Wernig, M; Wu, JC; Majeti, R Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Cell Stem Cell. 2017; 20(3): 329-344. [OPEN ACCESS]
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Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285 [OPEN ACCESS]
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Heitzer, E; Perakis, S; Geigl, JB; Speicher, MR The potential of liquid biopsies for the early detection of cancer.
NPJ Precis Oncol. 2017; 1(1):36-36 [OPEN ACCESS]
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Loibner, M; Oberauner-Wappis, L; Viertler, C; Groelz, D; Zatloukal, K Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation.
J Vis Exp. 2017; 8(130): [OPEN ACCESS]
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Phuah, CL; Dave, T; Malik, R; Raffeld, MR; Ayres, AM; Goldstein, JN; Viswanathan, A; Greenberg, SM; Jagiella, JM; Hansen, BM; Norrving, B; Jimenez-Conde, J; Roquer, J; Pichler, A; Enzinger, C; Montaner, J; Fernandez-Cadenas, I; Lindgren, A; Slowik, A; Schmidt, R; Biffi, A; Rost, N; Langefeld, CD; Markus, HS; Mitchell, BD; Worrall, BB; Kittner, SJ; Woo, D; Dichgans, M; Rosand, J; Anderson, CD; METASTROKE; NINDS-SiGN Consortium; International Stroke Genetics Consortium Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
Brain. 2017; 140(10):2663-2672 [OPEN ACCESS]
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Sliwa, T; Beham-Schmid, C; Burgstaller, S; Buxhofer-Ausch, V; Gastl, G; Geissler, K; Krauth, M; Krippl, P; Lang, A; Petzer, A; Wöhrer, S; Wölfler, A; Gisslinger, H Austrian recommendations for the management of primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis: an expert statement.
Wien Klin Wochenschr. 2017; 129(9-10):293-302 [OPEN ACCESS]
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2016

Grillo, F; Fassan, M; Sarocchi, F; Fiocca, R; Mastracci, L HER2 heterogeneity in gastric/gastroesophageal cancers: From benchside to practice.
World J Gastroenterol. 2016; 22(26):5879-5887 [OPEN ACCESS]
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Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781 [OPEN ACCESS]
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Oberauner-Wappis, L; Loibner, M; Viertler, C; Groelz, D; Wyrich, R; Zatloukal, K Protocol for HER2 FISH determination on PAXgene-fixed and paraffin-embedded tissue in breast cancer.
Int J Exp Pathol. 2016; 97(2):202-206 [OPEN ACCESS]
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Wolff, I; May, M; Hoschke, B; Zigeuner, R; Cindolo, L; Hutterer, G; Schips, L; De Cobelli, O; Rocco, B; De Nunzio, C; Tubaro, A; Coman, I; Feciche, B; Truss, M; Dalpiaz, O; Figenshau, RS; Madison, K; Sánchez-Chapado, M; Santiago Martin, MD; Salzano, L; Lotrecchiano, G; Shariat, SF; Hohenfellner, M; Waidelich, R; Stief, C; Miller, K; Pahernik, S; Brookman-May, S; Members of the CORONA Project and the European Association of Urology (EAU) Young Academic Urologists (YAU) Renal Cancer Group Do we need new high-risk criteria for surgically treated renal cancer patients to improve the outcome of future clinical trials in the adjuvant setting? Results of a comprehensive analysis based on the multicenter CORONA database.
Eur J Surg Oncol. 2016; 42(5):744-750
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Woltsche, N; Schwab, C; Deinlein, T; Hofmann-Wellenhof, R; Zalaudek, I Dermoscopy in the era of dermato-oncology: from bed to bench side and retour.
Expert Rev Anticancer Ther. 2016; 16(5):531-541
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2015

Bagdonaite, I; Wandall, HH; Litvinov, IV; Nastasi, C; Becker, JC; Dabelsteen, S; Geisler, C; Bonefeld, CM; Zhang, Q; Wasik, MA; Zhou, Y; Sasseville, D; Ødum, N; Woetmann, A Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients.
Oncotarget. 2015; 6(16):14374-14384 [OPEN ACCESS]
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Heitzer, E; Ulz, P; Geigl, JB Circulating tumor DNA as a liquid biopsy for cancer.
Clin Chem. 2015; 61(1):112-123 [OPEN ACCESS]
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Murali, R; Chandramohan, R; Möller, I; Scholz, SL; Berger, M; Huberman, K; Viale, A; Pirun, M; Socci, ND; Bouvier, N; Bauer, S; Artl, M; Schilling, B; Schimming, T; Sucker, A; Schwindenhammer, B; Grabellus, F; Speicher, MR; Schaller, J; Hillen, U; Schadendorf, D; Mentzel, T; Cheng, DT; Wiesner, T; Griewank, KG Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.
Oncotarget. 2015; 6(34):36041-36052 [OPEN ACCESS]
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Reintam Blaser, A; Deane, AM; Fruhwald, S Diarrhoea in the critically ill.
Curr Opin Crit Care. 2015; 21(2):142-153
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Shain, AH; Garrido, M; Botton, T; Talevich, E; Yeh, I; Sanborn, JZ; Chung, J; Wang, NJ; Kakavand, H; Mann, GJ; Thompson, JF; Wiesner, T; Roy, R; Olshen, AB; Gagnon, A; Gray, JW; Huh, N; Hur, JS; Busam, KJ; Scolyer, RA; Cho, RJ; Murali, R; Bastian, BC Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Nat Genet. 2015; 47(10): 1194-1199. [OPEN ACCESS]
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2014

Aigner, B; Ugurel, S; Kaddu, S; Becker, JC [Cutaneous sarcomas: update on selected fibrohistiocytic and myofibroblastic tumors].
Hautarzt. 2014; 65(7):614-622
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Bruns, H; Petrulionis, M; Schultze, D; Al Saeedi, M; Lin, S; Yamanaka, K; Ambrazevičius, M; Strupas, K; Schemmer, P Glycine inhibits angiogenic signaling in human hepatocellular carcinoma cells.
Amino Acids. 2014; 46(4):969-976
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Efficace, F; Rees, J; Fayers, P; Pusic, A; Taphoorn, M; Greimel, E; Reijneveld, J; Whale, K; Blazeby, J; European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Group Overcoming barriers to the implementation of patient-reported outcomes in cancer clinical trials: the PROMOTION Registry.
Health Qual Life Outcomes. 2014; 12(6):86-86 [OPEN ACCESS]
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Smolle, E; Taucher, V; Haybaeck, J Malignant ascites in ovarian cancer and the role of targeted therapeutics.
Anticancer Res. 2014; 34(4):1553-1561
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Zewinger, S; Speer, T; Kleber, ME; Scharnagl, H; Woitas, R; Lepper, PM; Pfahler, K; Seiler, S; Heine, GH; März, W; Silbernagel, G; Fliser, D HDL cholesterol is not associated with lower mortality in patients with kidney dysfunction.
J Am Soc Nephrol. 2014; 25(5):1073-1082 [OPEN ACCESS]
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2013

Aigner, B; Plötz, SG; Schaller, G Triple-negative breast cancer possibly transforming into malignant melanoma due to targeted therapy? A case report and review of literature.
Wien Med Wochenschr. 2013; 163(21-22): 495-498. (- Case Report)
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Degen, A; Weichenthal, M; Ugurel, S; Trefzer, U; Kilian, K; Garbe, C; Egberts, F; Poppe, LM; Hauschild, A; Gutzmer, R Cutaneous side effects of combined therapy with sorafenib and pegylated interferon alpha-2b in metastatic melanoma (phase II DeCOG trial).
J Dtsch Dermatol Ges. 2013; 11(9):846-853
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Scheipl, S; Lohberger, B; Rinner, B; Froehlich, EV; Beham, A; Quehenberger, F; Lazáry, A; Pal Varga, P; Haybaeck, J; Leithner, A; Liegl, B Histone deacetylase inhibitors as potential therapeutic approaches for chordoma: an immunohistochemical and functional analysis.
J Orthop Res. 2013; 31(12):1999-2005 [OPEN ACCESS]
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Szkandera, J; Kiesslich, T; Haybaeck, J; Gerger, A; Pichler, M Hedgehog signaling pathway in ovarian cancer.
Int J Mol Sci. 2013; 14(1):1179-1196 [OPEN ACCESS]
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2012

Min, L; Ji, Y; Bakiri, L; Qiu, Z; Cen, J; Chen, X; Chen, L; Scheuch, H; Zheng, H; Qin, L; Zatloukal, K; Hui, L; Wagner, EF Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.
Nat Cell Biol. 2012; 14(11):1203-1211
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Scheipl, S; Froehlich, EV; Leithner, A; Beham, A; Quehenberger, F; Mokry, M; Stammberger, H; Varga, PP; Lazary, A; Windhager, R; Gattenloehner, S; Liegl, B Does insulin-like growth factor 1 receptor (IGF-1R) targeting provide new treatment options for chordomas? A retrospective clinical and immunohistochemical study.
Histopathology. 2012; 60(6):999-1003
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2011

Sill, H; Olipitz, W; Zebisch, A; Schulz, E; Wölfler, A Therapy-related myeloid neoplasms: pathobiology and clinical characteristics.
Br J Pharmacol. 2011; 162(4): 792-805. [OPEN ACCESS]
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Sun, M; Shariat, SF; Cheng, C; Ficarra, V; Murai, M; Oudard, S; Pantuck, AJ; Zigeuner, R; Karakiewicz, PI Prognostic factors and predictive models in renal cell carcinoma: a contemporary review.
Eur Urol. 2011; 60(4): 644-661.
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2010

Kriegshäuser, G; Auner, V; Zeillinger, R New and potential clinical applications of KRAS as a cancer biomarker.
Expert Opin Med Diagn. 2010; 4(5):383-395
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Tomuleasa, C; Soritau, O; Rus-Ciuca, D; Pop, T; Todea, D; Mosteanu, O; Pintea, B; Foris, V; Susman, S; Kacsó, G; Irimie, A Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma.
J Gastrointestin Liver Dis. 2010; 19(1):61-67 [OPEN ACCESS]
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2009

Auner, V; Kriegshäuser, G; Tong, D; Horvat, R; Reinthaller, A; Mustea, A; Zeillinger, R KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay.
BMC Cancer. 2009; 9(1): 111-111. [OPEN ACCESS]
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Gnant, M; Dubsky, P; Fitzal, F; Blaha, P; Schoppmann, S; Steger, G; Marth, C; Samonigg, H; Hüttner, K; Fohler, H; Ruecklinger, E; Jakesz, R; Greil, R; Austrian Breast and Colorectal Cancer Study Group Maintaining bone density in patients undergoing treatment for breast cancer: is there an adjuvant benefit?
Clin Breast Cancer. 2009; 9 Suppl 1: S18-S27.
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Kovacs, G; Maier, R; Aberer, E; Brodmann, M; Scheidl, S; Tröster, N; Hesse, C; Salmhofer, W; Graninger, W; Gruenig, E; Rubin, LJ; Olschewski, H Borderline pulmonary arterial pressure is associated with decreased exercise capacity in scleroderma.
Am J Respir Crit Care Med. 2009; 180(9):881-886 [OPEN ACCESS]
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2008

Brunner, M; Thurnher, D; Pammer, J; Geleff, S; Heiduschka, G; Reinisch, CM; Petzelbauer, P; Erovic, BM Expression of VEGF-A/C, VEGF-R2, PDGF-alpha/beta, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma.
Mod Pathol. 2008; 21(7):876-884 [OPEN ACCESS]
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Gomberg-Maitland, M; Olschewski, H Prostacyclin therapies for the treatment of pulmonary arterial hypertension.
Eur Respir J. 2008; 31(4):891-901 [OPEN ACCESS]
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