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Publikationen

Suchbegriffe: PULMONARY ARTERIAL HYPERTENSION, . Treffer: 157

2023

Aktaa, S; Gale, CP; Brida, M; Giannakoulas, G; Kovacs, G; Adir, Y; Benza, RL; Böhm, M; Coats, A; D'Alto, M; Escribano-Subias, P; Ferrari, P; Galiè, N; Gibbs, JSR; Gin-Sing, W; Hoeper, MM; Humbert, M; Lang, IM; Maron, BA; Meszaros, G; Noordegraaf, AV; Price, LC; Pepke-Zaba, J; Rådegran, G; Reis, A; Sitbon, O; Torbicki, A; Ulrich, S; Rosenkranz, S; Delcroix, M European Society of Cardiology quality indicators for the care and outcomes of adults with pulmonary arterial hypertension. Developed in collaboration with the Heart Failure Association of the European Society of Cardiology.
Eur J Heart Fail. 2023; Doi: 10.1002/ejhf.2830
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Foris, V; Kovacs, G; Avian, A; Bálint, Z; Douschan, P; Ghanim, B; Klepetko, W; Olschewski, A; Olschewski, H Apelin-17 to diagnose idiopathic pulmonary arterial hypertension: A biomarker study.
Front Physiol. 2022; 13: 986295 Doi: 10.3389/fphys.2022.986295 [OPEN ACCESS]
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Richter, MJ; Fortuni, F; Alenezi, F; D'Alto, M; Badagliacca, R; Brunner, NW; van, Dijk, AP; Douschan, P; Gall, H; Ghio, S; Giudice, FL; Grünig, E; Haddad, F; Howard, L; Rajagopal, S; Stens, N; Stolfo, D; Thijssen, DHJ; Vizza, CD; Zamanian, RT; Zhong, L; Seeger, W; Ghofrani, HA; Tello, K Imaging the right atrium in pulmonary hypertension: A systematic review and meta-analysis.
J Heart Lung Transplant. 2023; 42(4):433-446 Doi: 10.1016/j.healun.2022.11.007
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van, der, Have, O; Mead, TJ; Westöö, C; Peruzzi, N; Mutgan, AC; Norvik, C; Bech, M; Struglics, A; Hoetzenecker, K; Brunnström, H; Westergren-Thorsson, G; Kwapiszewska, G; Apte, SS; Tran-Lundmark, K Aggrecan accumulates at sites of increased pulmonary arterial pressure in idiopathic pulmonary arterial hypertension.
Pulm Circ. 2023; 13(1):e12200 Doi: 10.1002/pul2.12200 [OPEN ACCESS]
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2022

Crnkovic, S; Valzano, F; Fließer, E; Gindlhuber, J; Thekkekara, Puthenparampil, H; Basil, M; Morley, MP; Katzen, J; Gschwandtner, E; Klepetko, W; Cantu, E; Wolinski, H; Olschewski, H; Lindenmann, J; Zhao, YY; Morrisey, EE; Marsh, LM; Kwapiszewska, G Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling.
JCI Insight. 2022; 7(20): Doi: 10.1172/jci.insight.153471 [OPEN ACCESS]
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Harbaum, L; Rhodes, CJ; Wharton, J; Lawrie, A; Karnes, JH; Desai, AA; Nichols, WC; Humbert, M; Montani, D; Girerd, B; Sitbon, O; Boehm, M; Novoyatleva, T; Schermuly, RT; Ghofrani, HA; Toshner, M; Kiely, DG; Howard, LS; Swietlik, EM; Gräf, S; Pietzner, M; Morrell, NW; Wilkins, MR, , U.K., National, Institute, for, Health, Research, BioResource, Rare, Diseases, Consortium, U.K., Pulmonary, Arterial, Hypertension, Cohort, Study, Consortium, and, U.S., Pulmonary, Arterial, Hypertension, Biobank, Consortium Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.
Am J Respir Crit Care Med. 2022; 205(12): 1449-1460. Doi: 10.1164/rccm.202109-2106OC [OPEN ACCESS]
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Humbert, M; Kovacs, G; Hoeper, MM; Badagliacca, R; Berger, RMF; Brida, M; Carlsen, J; Coats, AJS; Escribano-Subias, P; Ferrari, P; Ferreira, DS; Ghofrani, HA; Giannakoulas, G; Kiely, DG; Mayer, E; Meszaros, G; Nagavci, B; Olsson, KM; Pepke-Zaba, J; Quint, JK; Rådegran, G; Simonneau, G; Sitbon, O; Tonia, T; Toshner, M; Vachiery, JL; Vonk, Noordegraaf, A; Delcroix, M; Rosenkranz, S, , ESC/ERS, Scientific, Document, Group 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.
Eur Heart J. 2022; 43(38):3618-3731 Doi: 10.1093/eurheartj/ehac237
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Kremer, N; Rako, Z; Douschan, P; Gall, H; Ghofrani, HA; Grimminger, F; Guth, S; Naeije, R; Rieth, A; Schulz, R; Seeger, W; Tedford, RJ; Vadász, I; Vanderpool, R; Wiedenroth, CB; Richter, MJ; Tello, K Unmasking right ventricular-arterial uncoupling during fluid challenge in pulmonary hypertension.
J Heart Lung Transplant. 2022; 41(3):345-355 Doi: 10.1016/j.healun.2021.11.019
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Sinha, M; Zabini, D; Guntur, D; Nagaraj, C; Enyedi, P; Olschewski, H; Kuebler, WM; Olschewski, A Chloride channels in the lung: Challenges and perspectives for viral infections, pulmonary arterial hypertension, and cystic fibrosis.
Pharmacol Ther. 2022; 237:108249 Doi: 10.1016/j.pharmthera.2022.108249
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Veith, C; Vartürk-Özcan, I; Wujak, M; Hadzic, S; Wu, CY; Knoepp, F; Kraut, S; Petrovic, A; Gredic, M; Pak, O; Brosien, M; Heimbrodt, M; Wilhelm, J; Weisel, FC; Malkmus, K; Schäfer, K; Gall, H; Tello, K; Kosanovic, D; Sydykov, A; Sarybaev, A; Günther, A; Brandes, RP; Seeger, W; Grimminger, F; Ghofrani, HA; Schermuly, RT; Kwapiszewska, G; Sommer, N; Weissmann, N SPARC, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension.
Circulation. 2022; 145(12):916-933 Doi: 10.1161/CIRCULATIONAHA.121.057001
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2021

Diekmann, F; Chouvarine, P; Sallmon, H; Meyer-Kobbe, L; Kieslich, M; Plouffe, BD; Murthy, SK; Lichtinghagen, R; Legchenko, E; Hansmann, G Soluble Receptor for Advanced Glycation End Products (sRAGE) Is a Sensitive Biomarker in Human Pulmonary Arterial Hypertension.
Int J Mol Sci. 2021; 22(16): Doi: 10.3390/ijms22168591 [OPEN ACCESS]
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Fließer, E; Birnhuber, A; Marsh, LM; Gschwandtner, E; Klepetko, W; Olschewski, H; Kwapiszewska, G Dysbalance of ACE2 levels - a possible cause for severe COVID-19 outcome in COPD.
J Pathol Clin Res. 2021; 7(5):446-458 Doi: 10.1002/cjp2.224 [OPEN ACCESS]
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Foris, V; Kovacs, G; Olschewski, H Update on pulmonary hypertension focusing on lung diseases
PNEUMOLOGE. 2021; 18(3): 195-206. Doi: 10.1007/s10405-021-00392-3
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Hoeper, MM; Al-Hiti, H; Benza, RL; Chang, SA; Corris, PA; Gibbs, JSR; Grünig, E; Jansa, P; Klinger, JR; Langleben, D; McLaughlin, VV; Meyer, GMB; Ota-Arakaki, J; Peacock, AJ; Pulido, T; Rosenkranz, S; Vizza, CD; Vonk-Noordegraaf, A; White, RJ; Chang, M; Kleinjung, F; Meier, C; Paraschin, K; Ghofrani, HA; Simonneau, G; REPLACE investigators Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial.
Lancet Respir Med. 2021; Doi: 10.1016/S2213-2600(20)30532-4
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Jud, P; Meinitzer, A; Strohmaier, H; Schwantzer, G; Foris, V; Kovacs, G; Avian, A; Odler, B; Moazedi-Furst, F; Brodmann, M; Hafner, F Evaluation of endothelial dysfunction and clinical events in patients with early-stage vasculopathy in limited systemic sclerosis
CLIN EXP RHEUMATOL. 2021; 39(4): S57-S65.
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Kovacs, G; Olschewski, H The definition of pulmonary hypertension: history, practical implications and current controversies
BREATHE. 2021; 17(3): 210076 Doi: 10.1183/20734735.0076-2021 [OPEN ACCESS]
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Le, Ribeuz, H; To, L; Ghigna, MR; Martin, C; Nagaraj, C; Dreano, E; Rucker-Martin, C; Girerd, B; Bouligand, J; Pechoux, C; Lambert, M; Boet, A; Issard, J; Mercier, O; Hoetzenecker, K; Manoury, B; Becq, F; Burgel, PR; Cottart, CH; Olschewski, A; Sermet-Gaudelus, I; Perros, F; Humbert, M; Montani, D; Antigny, F Involvement of CFTR in the pathogenesis of pulmonary arterial hypertension.
Eur Respir J. 2021; 58(5): Doi: 10.1183/13993003.00653-2020
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Mandras, S; Kovacs, G; Olschewski, H; Broderick, M; Nelsen, A; Shen, E; Champion, H Combination Therapy in Pulmonary Arterial Hypertension-Targeting the Nitric Oxide and Prostacyclin Pathways.
J Cardiovasc Pharmacol Ther. 2021; 26(5):453-462 Doi: 10.1177/10742484211006531 [OPEN ACCESS]
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Maron, BA; Abman, SH; Elliott, CG; Frantz, RP; Hopper, RK; Horn, EM; Nicolls, MR; Shlobin, OA; Shah, SJ; Kovacs, G; Olschewski, H; Rosenzweig, EB Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances.
Am J Respir Crit Care Med. 2021; 203(12): 1472-1487. Doi: 10.1164/rccm.202012-4317SO [OPEN ACCESS]
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Meinel, K; Koestenberger, M; Sallmon, H; Hansmann, G; Pieles, GE Echocardiography for the Assessment of Pulmonary Hypertension and Congenital Heart Disease in the Young.
Diagnostics (Basel). 2020; 11(1): Doi: 10.3390/diagnostics11010049 [OPEN ACCESS]
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Olschewski, H The Challenge to Decide between Pulmonary Hypertension Due to Chronic Lung Disease and PAH with Chronic Lung Disease.
DIAGNOSTICS. 2021; 11(2): 311 Doi: 10.3390/diagnostics11020311 [OPEN ACCESS]
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2020

Hansmann, G; Meinel, K; Bukova, M; Chouvarine, P; Wåhlander, H; Koestenberger, M; European Pediatric Pulmonary Vascular Disease Network (EPPVDN) Selexipag for the treatment of children with pulmonary arterial hypertension: First multicenter experience in drug safety and efficacy.
J Heart Lung Transplant. 2020; 39(7):695-706 Doi: 10.1016/j.healun.2020.03.029 [OPEN ACCESS]
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Hasan, B; Hansmann, G; Budts, W; Heath, A; Hoodbhoy, Z; Jing, ZC; Koestenberger, M; Meinel, K; Mocumbi, AO; Radchenko, GD; Sallmon, H; Sliwa, K; Kumar, RK; European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, CSC, PASCAR, PCS, and PCSI Challenges and Special Aspects of Pulmonary Hypertension in Middle- to Low-Income Regions: JACC State-of-the-Art Review.
J Am Coll Cardiol. 2020; 75(19):2463-2477 Doi: 10.1016/j.jacc.2020.03.047 [OPEN ACCESS]
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Hodgson, J; Swietlik, EM; Salmon, RM; Hadinnapola, C; Nikolic, I; Wharton, J; Guo, J; Liley, J; Haimel, M; Bleda, M; Southgate, L; Machado, RD; Martin, JM; Treacy, CM; Yates, K; Daugherty, LC; Shamardina, O; Whitehorn, D; Holden, S; Bogaard, HJ; Church, C; Coghlan, G; Condliffe, R; Corris, PA; Danesino, C; Eyries, M; Gall, H; Ghio, S; Ghofrani, HA; Gibbs, JSR; Girerd, B; Houweling, AC; Howard, L; Humbert, M; Kiely, DG; Kovacs, G; Lawrie, A; MacKenzie Ross, RV; Moledina, S; Montani, D; Olschewski, A; Olschewski, H; Ouwehand, WH; Peacock, AJ; Pepke-Zaba, J; Prokopenko, I; Rhodes, CJ; Scelsi, L; Seeger, W; Soubrier, F; Suntharalingam, J; Toshner, MR; Trembath, RC; Noordegraaf, AV; Wort, SJ; Wilkins, MR; Yu, PB; Li, W; Gräf, S; Upton, PD; Morrell, NW Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension.
Am J Respir Crit Care Med. 2020; 201(5):575-585 Doi: 10.1164/rccm.201906-1141OC [OPEN ACCESS]
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Inampudi, C; Tedford, RJ; Hemnes, AR; Hansmann, G; Bogaard, HJ; Koestenberger, M; Lang, IM; Brittain, EL Treatment of right ventricular dysfunction and heart failure in pulmonary arterial hypertension.
Cardiovasc Diagn Ther. 2020; 10(5):1659-1674 Doi: 10.21037/cdt-20-348 [OPEN ACCESS]
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Jandl, K; Marsh, LM; Hoffmann, J; Mutgan, AC; Baum, O; Bloch, W; Thekkekara-Puthenparampil, H; Kolb, D; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Olschewski, H; Kwapiszewska, G Basement Membrane Remodeling Controls Endothelial Function in Idiopathic Pulmonary Arterial Hypertension.
Am J Respir Cell Mol Biol. 2020; 63(1):104-117 Doi: 10.1165/rcmb.2019-0303OC
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Kaemmerer, H; Gorenflo, M; Huscher, D; Pittrow, D; Apitz, C; Baumgartner, H; Berger, F; Bruch, L; Brunnemer, E; Budts, W; Claussen, M; Coghlan, G; Dähnert, I; D'Alto, M; Delcroix, M; Distler, O; Dittrich, S; Dumitrescu, D; Ewert, R; Faehling, M; Germund, I; Ghofrani, HA; Grohé, C; Grossekreymborg, K; Halank, M; Hansmann, G; Harzheim, D; Nemes, A; Havasi, K; Held, M; Hoeper, MM; Hofbeck, M; Hohenfrost-Schmidt, W; Jurevičienė, E; Gumbienè, L; Kabitz, HJ; Klose, H; Köhler, T; Konstantinides, S; Köestenberger, M; Kozlik-Feldmann, R; Kramer, HH; Kropf-Sanchen, C; Lammers, A; Lange, T; Meyn, P; Miera, O; Milger-Kneidinger, K; Neidenbach, R; Neurohr, C; Opitz, C; Perings, C; Remppis, BA; Riemekasten, G; Scelsi, L; Scholtz, W; Simkova, I; Skowasch, D; Skride, A; Stähler, G; Stiller, B; Tsangaris, I; Vizza, CD; Vonk Noordegraaf, A; Wilkens, H; Wirtz, H; Diller, GP; Grünig, E; Rosenkranz, S Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry.
J Clin Med. 2020; 9(5): Doi: 10.3390/jcm9051456 [OPEN ACCESS]
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Mutgan, AC; Jandl, K; Kwapiszewska, G Endothelial Basement Membrane Components and Their Products, Matrikines: Active Drivers of Pulmonary Hypertension?
Cells. 2020; 9(9): Doi: 10.3390/cells9092029 [OPEN ACCESS]
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Ramjug, S; Weatherald, J; Sahay, S; Khoury, J; Foris, V; Chandran, N; Bokan, A; Godinas, L; Delcroix, M ERS International Congress, Madrid, 2019: highlights from the Pulmonary Vascular Diseases Assembly.
ERJ Open Res. 2020; 6(4): Doi: 10.1183/23120541.00304-2020 [OPEN ACCESS]
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Schweintzger, S; Koestenberger, M; Schlagenhauf, A; Grangl, G; Burmas, A; Kurath-Koller, S; Pocivalnik, M; Sallmon, H; Baumgartner, D; Hansmann, G; Gamillscheg, A Safety and efficacy of the endothelin receptor antagonist macitentan in pediatric pulmonary hypertension.
Cardiovasc Diagn Ther. 2020; 10(5):1675-1685 Doi: 10.21037/cdt.2020.04.01 [OPEN ACCESS]
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Skofic Maurer, D; Zabini, D; Nagaraj, C; Sharma, N; Lengyel, M; Nagy, BM; Frank, S; Klepetko, W; Gschwandtner, E; Enyedi, P; Kwapiszewska, G; Olschewski, H; Olschewski, A Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries.
Cells. 2020; 9(9): Doi: 10.3390/cells9091984 [OPEN ACCESS]
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Swietlik, EM; Greene, D; Zhu, N; Megy, K; Cogliano, M; Rajaram, S; Pandya, D; Tilly, T; Lutz, KA; Welch, CCL; Pauciulo, MW; Southgate, L; Martin, JM; Treacy, CM; Penkett, CJ; Stephens, JC; Bogaard, HJ; Church, C; Coghlan, G; Coleman, AW; Condliffe, R; Eichstaedt, CA; Eyries, M; Gall, H; Ghio, S; Girerd, B; Grünig, E; Holden, S; Howard, L; Humbert, M; Kiely, DG; Kovacs, G; Lordan, J; Machado, RD; Mackenzie, Ross, RV; McCabe, C; Moledina, S; Montani, D; Olschewski, H; Pepke-Zaba, J; Price, L; Rhodes, CJ; Seeger, W; Soubrier, F; Suntharalingam, J; Toshner, MR; Vonk, Noordegraaf, A; Wharton, J; Wild, JM; Wort, SJ; Lawrie, A; Wilkins, MR; Trembath, RC; Shen, Y; Chung, WK; Swift, AJ; Nichols, WC; Morrell, NW; Gräf, S Bayesian Inference Associates Rare KDR Variants with Specific Phenotypes in Pulmonary Arterial Hypertension.
Circ Genom Precis Med. 2020; 14(1):e003155 Doi: 10.1161/CIRCGEN.120.003155 [OPEN ACCESS]
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2019

Crnkovic, S; Egemnazarov, B; Damico, R; Marsh, LM; Nagy, BM; Douschan, P; Atsina, K; Kolb, TM; Mathai, SC; Hooper, JE; Ghanim, B; Klepetko, W; Fruhwald, F; Lassner, D; Olschewski, A; Olschewski, H; Hassoun, PM; Kwapiszewska, G Disconnect between Fibrotic Response and Right Ventricular Dysfunction.
Am J Respir Crit Care Med. 2019; 199(12):1550-1560 Doi: 10.1164/rccm.201809-1737OC [OPEN ACCESS]
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Foris, V; Brcic, L; Douschan, P; Kovacs, G; Stacher-Priehse, E; Olschewski, H Advanced interstitial lung fibrosis with emphysema and pulmonary hypertension with no evidence for interstitial lung disease on high resolution CT.
Pulm Circ. 2019; 9(3): 2045894019832214 Doi: 10.1177/2045894019832214 [OPEN ACCESS]
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Humbert, M; Guignabert, C; Bonnet, S; Dorfmüller, P; Klinger, JR; Nicolls, MR; Olschewski, AJ; Pullamsetti, SS; Schermuly, RT; Stenmark, KR; Rabinovitch, M Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives.
Eur Respir J. 2019; 53(1): Doi: 10.1183/13993003.01887-2018 [OPEN ACCESS]
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Jandl, K; Thekkekara Puthenparampil, H; Marsh, LM; Hoffmann, J; Wilhelm, J; Veith, C; Sinn, K; Klepetko, W; Olschewski, H; Olschewski, A; Brock, M; Kwapiszewska, G Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1.
J Pathol. 2019; 247(3):357-370 Doi: 10.1002/path.5195 [OPEN ACCESS]
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Koestenberger, M; Sallmon, H; Hansmann, G; European Pediatric Pulmonary Vascular Disease Network A pediatric perspective on the TAPSE/PASP ratio in pulmonary arterial hypertension.
INT J CARDIOL. 2019; 278: 242-242. Doi: 10.1016/j.ijcard.2018.11.092
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Kwapiszewska, G; Johansen, AKZ; Gomez-Arroyo, J; Voelkel, NF Role of the Aryl Hydrocarbon Receptor/ARNT/Cytochrome P450 System in Pulmonary Vascular Diseases.
Circ Res. 2019; 125(3):356-366 Doi: 10.1161/CIRCRESAHA.119.315054
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Papp, R; Nagaraj, C; Zabini, D; Nagy, BM; Lengyel, M; Skofic Maurer, D; Sharma, N; Egemnazarov, B; Kovacs, G; Kwapiszewska, G; Marsh, LM; Hrzenjak, A; Höfler, G; Didiasova, M; Wygrecka, M; Sievers, LK; Szucs, P; Enyedi, P; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension.
Eur Respir J. 2019; 53(6): 1800965 Doi: 10.1183/13993003.00965-2018
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Rhodes, CJ; Batai, K; Bleda, M; Haimel, M; Southgate, L; Germain, M; Pauciulo, MW; Hadinnapola, C; Aman, J; Girerd, B; Arora, A; Knight, J; Hanscombe, KB; Karnes, JH; Kaakinen, M; Gall, H; Ulrich, A; Harbaum, L; Cebola, I; Ferrer, J; Lutz, K; Swietlik, EM; Ahmad, F; Amouyel, P; Archer, SL; Argula, R; Austin, ED; Badesch, D; Bakshi, S; Barnett, C; Benza, R; Bhatt, N; Bogaard, HJ; Burger, CD; Chakinala, M; Church, C; Coghlan, JG; Condliffe, R; Corris, PA; Danesino, C; Debette, S; Elliott, CG; Elwing, J; Eyries, M; Fortin, T; Franke, A; Frantz, RP; Frost, A; Garcia, JGN; Ghio, S; Ghofrani, HA; Gibbs, JSR; Harley, J; He, H; Hill, NS; Hirsch, R; Houweling, AC; Howard, LS; Ivy, D; Kiely, DG; Klinger, J; Kovacs, G; Lahm, T; Laudes, M; Machado, RD; MacKenzie Ross, RV; Marsolo, K; Martin, LJ; Moledina, S; Montani, D; Nathan, SD; Newnham, M; Olschewski, A; Olschewski, H; Oudiz, RJ; Ouwehand, WH; Peacock, AJ; Pepke-Zaba, J; Rehman, Z; Robbins, I; Roden, DM; Rosenzweig, EB; Saydain, G; Scelsi, L; Schilz, R; Seeger, W; Shaffer, CM; Simms, RW; Simon, M; Sitbon, O; Suntharalingam, J; Tang, H; Tchourbanov, AY; Thenappan, T; Torres, F; Toshner, MR; Treacy, CM; Vonk Noordegraaf, A; Waisfisz, Q; Walsworth, AK; Walter, RE; Wharton, J; White, RJ; Wilt, J; Wort, SJ; Yung, D; Lawrie, A; Humbert, M; Soubrier, F; Trégouët, DA; Prokopenko, I; Kittles, R; Gräf, S; Nichols, WC; Trembath, RC; Desai, AA; Morrell, NW; Wilkins, MR; UK NIHR BioResource Rare Diseases Consortium; UK PAH Cohort Study Consortium; US PAH Biobank Consortium Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
Lancet Respir Med. 2019; 7(3):227-238 Doi: 10.1016/S2213-2600(18)30409-0 [OPEN ACCESS]
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Rosenkranz, S; Diller, GP; Dumitrescu, D; Ewert, R; Ghofrani, HA; Grünig, E; Halank, M; Held, M; Kaemmerer, H; Klose, H; Kovacs, G; Konstantinides, S; Lang, IM; Lange, TJ; Leuchte, H; Mayer, E; Olschewski, A; Olschewski, H; Olsson, KM; Opitz, C; Schermuly, RT; Seeger, W; Wilkens, H; Hoeper, MM [Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension].
Dtsch Med Wochenschr. 2019; 144(19):1367-1372 Doi: 10.1055/a-0918-3772 [OPEN ACCESS]
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Spiekerkoetter, E; Goncharova, EA; Guignabert, C; Stenmark, K; Kwapiszewska, G; Rabinovitch, M; Voelkel, N; Bogaard, HJ; Graham, B; Pullamsetti, SS; Kuebler, WM Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure.
Pulm Circ. 2019; 9(4): 2045894019889775-2045894019889775. Doi: 10.1177/2045894019889775 [OPEN ACCESS]
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Zucker, MM; Wujak, L; Gungl, A; Didiasova, M; Kosanovic, D; Petrovic, A; Klepetko, W; Schermuly, RT; Kwapiszewska, G; Schaefer, L; Wygrecka, M LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(6):1604-1616 Doi: 10.1016/j.bbadis.2019.03.012 [OPEN ACCESS]
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2018

Biasin, V; Wygrecka, M; Bärnthaler, T; Jandl, K; Jain, PP; Bálint, Z; Kovacs, G; Leitinger, G; Kolb-Lenz, D; Kornmueller, K; Peters, F; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Becker-Pauly, C; Kwapiszewska, G Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Thromb Haemost. 2018; 118(10):1790-1802 Doi: 10.1055/s-0038-1670657
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Crnkovic, S; Marsh, LM; El Agha, E; Voswinckel, R; Ghanim, B; Klepetko, W; Stacher-Priehse, E; Olschewski, H; Bloch, W; Bellusci, S; Olschewski, A; Kwapiszewska, G Resident cell lineages are preserved in pulmonary vascular remodeling.
J Pathol. 2018; 244(4):485-498 Doi: 10.1002/path.5044 [OPEN ACCESS]
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Douschan, P; Kovacs, G; Foris, V; Kuehnelt-Leddihn, M; Olschewski, H Imatinib for right heart failure in COPD.
Pulm Circ. 2018; 9(1):2045894018816974-2045894018816974 Doi: 10.1177/2045894018816974 (- Case Report) [OPEN ACCESS]
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Fazakas, C; Nagaraj, C; Zabini, D; Végh, AG; Marsh, LM; Wilhelm, I; Krizbai, IA; Olschewski, H; Olschewski, A; Bálint, Z Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.
Front Physiol. 2018; 9:537-537 Doi: 10.3389/fphys.2018.00537 [OPEN ACCESS]
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Gräf, S; Haimel, M; Bleda, M; Hadinnapola, C; Southgate, L; Li, W; Hodgson, J; Liu, B; Salmon, RM; Southwood, M; Machado, RD; Martin, JM; Treacy, CM; Yates, K; Daugherty, LC; Shamardina, O; Whitehorn, D; Holden, S; Aldred, M; Bogaard, HJ; Church, C; Coghlan, G; Condliffe, R; Corris, PA; Danesino, C; Eyries, M; Gall, H; Ghio, S; Ghofrani, HA; Gibbs, JSR; Girerd, B; Houweling, AC; Howard, L; Humbert, M; Kiely, DG; Kovacs, G; MacKenzie Ross, RV; Moledina, S; Montani, D; Newnham, M; Olschewski, A; Olschewski, H; Peacock, AJ; Pepke-Zaba, J; Prokopenko, I; Rhodes, CJ; Scelsi, L; Seeger, W; Soubrier, F; Stein, DF; Suntharalingam, J; Swietlik, EM; Toshner, MR; van Heel, DA; Vonk Noordegraaf, A; Waisfisz, Q; Wharton, J; Wort, SJ; Ouwehand, WH; Soranzo, N; Lawrie, A; Upton, PD; Wilkins, MR; Trembath, RC; Morrell, NW Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.
Nat Commun. 2018; 9(1): 1416-1416. Doi: 10.1038/s41467-018-03672-4 [OPEN ACCESS]
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Koestenberger, M; Avian, A; Gamillscheg, A; Sallmon, H; Grangl, G; Burmas, A; Schweintzger, S; Kurath-Koller, S; Cvirn, G; Hansmann, G Right ventricular base/apex ratio in the assessment of pediatric pulmonary arterial hypertension: Results from the European Pediatric Pulmonary Vascular Disease Network.
Clin Cardiol. 2018; 41(9):1144-1149 Doi: 10.1002/clc.22994 [OPEN ACCESS]
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Koestenberger, M; Hansmann, G Should we use the oral selective IP receptor agonist selexipag off-label in children with pulmonary arterial hypertension?
Pulm Circ. 2018; 8(3):2045894018793580-2045894018793580 Doi: 10.1177/2045894018793580 [OPEN ACCESS]
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