Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: PROSTACYCLIN, . Treffer: 73

2019

Themanns, M; Koban, F; Bergmayr, C; Chrzan, A; Strohmaier, W; Haybaeck, J; Freissmuth, M; Zebedin-Brandl, E Treprostinil reduces endothelial damage in murine sinusoidal obstruction syndrome.
J Mol Med (Berl). 2019; 97(2):201-213 [OPEN ACCESS]
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2018

Koestenberger, M; Hansmann, G Should we use the oral selective IP receptor agonist selexipag off-label in children with pulmonary arterial hypertension?
PULM CIRC. 2018; 8(3): UNSP 2045894018793580 [OPEN ACCESS]
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2017

Drobnjak, T; Gizurarson, S; Gokina, NI; Meiri, H; Mandalá, M; Huppertz, B; Osol, G Placental protein 13 (PP13)-induced vasodilation of resistance arteries from pregnant and nonpregnant rats occurs via endothelial-signaling pathways.
Hypertens Pregnancy. 2017; 36(2):186-195
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Gessler, T; Ghofrani, HA; Held, M; Klose, H; Leuchte, H; Olschewski, H; Rosenkranz, S; Fels, L; Li, N; Ren, D; Kaiser, A; Schultze-Mosgau, MH; Müllinger, B; Rohde, B; Seeger, W The safety and pharmacokinetics of rapid iloprost aerosol delivery via the BREELIB nebulizer in pulmonary arterial hypertension.
Pulm Circ. 2017; 7(2):505-513 [OPEN ACCESS]
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Riederer, M; Lechleitner, M; Köfeler, H; Frank, S Reduced expression of adipose triglyceride lipase decreases arachidonic acid release and prostacyclin secretion in human aortic endothelial cells.
Arch Physiol Biochem. 2017; 123(4):249-253 [OPEN ACCESS]
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2014

Jain, PP; Leber, R; Nagaraj, C; Leitinger, G; Lehofer, B; Olschewski, H; Olschewski, A; Prassl, R; Marsh, LM Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries.
Int J Nanomedicine. 2014; 9(3):3249-3261 [OPEN ACCESS]
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Kozina, A; Opresnik, S; Wong, MS; Hallström, S; Graier, WF; Malli, R; Schröder, K; Schmidt, K; Frank, S Oleoyl-lysophosphatidylcholine limits endothelial nitric oxide bioavailability by induction of reactive oxygen species.
PLoS One. 2014; 9(11):e113443-e113443 [OPEN ACCESS]
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Olschewski, A; Papp, R; Nagaraj, C; Olschewski, H Ion channels and transporters as therapeutic targets in the pulmonary circulation.
Pharmacol Ther. 2014; 144(3):349-368
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2013

Olschewski, H Prostacyclins.
Handb Exp Pharmacol. 2013; 218(3):177-198
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Rao, SP; Riederer, M; Lechleitner, M; Hermansson, M; Desoye, G; Hallström, S; Graier, WF; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on endothelium-dependent vasorelaxation.
PLoS One. 2013; 8(5):e65155-e65155 [OPEN ACCESS]
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2012

Li, Y; Connolly, M; Nagaraj, C; Tang, B; Bálint, Z; Popper, H; Smolle-Juettner, FM; Lindenmann, J; Kwapiszewska, G; Aaronson, PI; Wohlkoenig, C; Leithner, K; Olschewski, H; Olschewski, A Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation.
Am J Respir Cell Mol Biol. 2012; 46(3):372-379
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2010

Krisper, P; Tiran, B; Fliser, D; Haditsch, B; Stadlbauer, V; Otto, R; Ernst, T; Kretschmer, U; Stauber, RE; Haller, H; Holzer, H; Manns, MP; Rifai, K Efficacy and safety of anticoagulation with heparin versus heparin plus epoprostenol in patients undergoing extracorporeal liver support with prometheus.
Artif Organs. 2010; 34(1): 84-88.
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McLaughlin, VV; Benza, RL; Rubin, LJ; Channick, RN; Voswinckel, R; Tapson, VF; Robbins, IM; Olschewski, H; Rubenfire, M; Seeger, W Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial.
J AMER COLL CARDIOL. 2010; 55(18): 1915-1922. [OPEN ACCESS]
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Nikam, VS; Schermuly, RT; Dumitrascu, R; Weissmann, N; Kwapiszewska, G; Morrell, N; Klepetko, W; Fink, L; Seeger, W; Voswinckel, R Treprostinil inhibits the recruitment of bone marrow-derived circulating fibrocytes in chronic hypoxic pulmonary hypertension.
Eur Respir J. 2010; 36(6):1302-1314 [OPEN ACCESS]
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Olschewski, A Targeting TASK-1 Channels as a Therapeutic Approach
ADVAN EXPERIMENT MED BIOL. 2010; 661: 459-473.
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Philipose, S; Konya, V; Sreckovic, I; Marsche, G; Lippe, IT; Peskar, BA; Heinemann, A; Schuligoi, R The Prostaglandin E2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation.
Arterioscler Thromb Vasc Biol. 2010; 30(12): 2416-2423. [OPEN ACCESS]
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Riederer, M; Ojala, PJ; Hrzenjak, A; Graier, WF; Malli, R; Tritscher, M; Hermansson, M; Watzer, B; Schweer, H; Desoye, G; Heinemann, A; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production.
J Lipid Res. 2010; 51(10):2957-2966 [OPEN ACCESS]
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2009

Voswinckel, R; Reichenberger, F; Gall, H; Schmehl, T; Gessler, T; Schermuly, RT; Grimminger, F; Rubin, LJ; Seeger, W; Ghofrani, HA; Olschewski, H Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension.
Pulm Pharmacol Ther. 2009; 22(1): 50-56.
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2008

Gomberg-Maitland, M; Olschewski, H Prostacyclin therapies for the treatment of pulmonary arterial hypertension.
Eur Respir J. 2008; 31(4):891-901 [OPEN ACCESS]
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Jaksch, W; Dejaco, C; Schirmer, M 4 years after withdrawal of rofecoxib: where do we stand today?
Rheumatol Int. 2008; 28(12): 1187-1195.
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2007

Mereles, D; Ewert, R; Lodziewski, S; Borst, MM; Benz, A; Olschewski, H; Grunig, E Effect of inhaled iloprost during off-medication time in patients with pulmonary arterial hypertension.
RESPIRATION. 2007; 74(5): 498-502.
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2006

Channick, RN; Olschewski, H; Seeger, W; Staub, T; Voswinckel, R; Rubin, LJ Safety and efficacy of inhaled treprostinil as add-on therapy to bosentan in pulmonary arterial hypertension.
J AMER COLL CARDIOL. 2006; 48(7): 1433-1437. [OPEN ACCESS]
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Rosengarten, B; Schermuly, RT; Voswinckel, R; Kohstall, MG; Olschewski, H; Weissmann, N; Seeger, W; Kaps, M; Grimminger, F; Ghofrani, HA Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension.
Cerebrovasc Dis. 2006; 21(3):194-200
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2005

Lackner, H; Benesch, M; Moser, A; Smolle-Jüttner, F; Linhart, W; Raith, J; Urban, C Aseptic osteonecrosis in children and adolescents treated for hemato-oncologic diseases: a 13-year longitudinal observational study.
J PEDIAT HEMATOL ONCOL. 2005; 27(5): 259-263.
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2004

Badesch, DB; McLaughlin, VV; Delcroix, M; Vizza, CD; Olschewski, H; Sitbon, O; Barst, RJ Prostanoid therapy for pulmonary arterial hypertension.
J Am Coll Cardiol. 2004; 43(12 Suppl S):56S-561 [OPEN ACCESS]
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Ghofrani, HA; Friese, G; Discher, T; Olschewski, H; Schermuly, RT; Weissmann, N; Seeger, W; Grimminger, F; Lohmeyer, J Inhaled iloprost is a potent acute pulmonary vasodilator in HIV-related severe pulmonary hypertension.
Eur Respir J. 2004; 23(2):321-326 [OPEN ACCESS]
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Olschewski, H; Rose, F; Schermuly, R; Ghofrani, HA; Enke, B; Olschewski, A; Seeger, W Prostacyclin and its analogues in the treatment of pulmonary hypertension.
Pharmacol Ther. 2004; 102(2):139-153
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Takahashi, Y; Poteser, M; Negoro, M; Wakabayashi, I Reduction of lipopolysaccharide-induced cyclooxygenase-2 expression in diabetic arteries.
Naunyn Schmiedebergs Arch Pharmacol. 2004; 369(3):358-362
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2003

Bali, G; Aberer, E Iloprost therapy in systemic sclerosis
Hautarzt. 2003; 54(9):845-851
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Fruhwald, FM; Kjellström, B; Perthold, W; Watzinger, N; Maier, R; Grandjean, PA; Klein, W Continuous hemodynamic monitoring in pulmonary hypertensive patients treated with inhaled iloprost.
Chest. 2003; 124(1):351-359 [OPEN ACCESS]
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Graninger, W Therapy of pulmonary involvement of rheumatic diseases
Z Rheumatol. 2003; 62(1):10-15
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Lang, I; Pabst, MA; Hiden, U; Blaschitz, A; Dohr, G; Hahn, T; Desoye, G Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells.
EUR J CELL BIOL 2003 82: 163-173.
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Olschewski, H; Rohde, B; Behr, J; Ewert, R; Gessler, T; Ghofrani, HA; Schmehl, T Pharmacodynamics and pharmacokinetics of inhaled iloprost, aerosolized by three different devices, in severe pulmonary hypertension.
Chest. 2003; 124(4):1294-1304 [OPEN ACCESS]
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Schermuly, RT; Leuchte, H; Ghofrani, HA; Weissmann, N; Rose, F; Kohstall, M; Olschewski, H; Schudt, C; Grimminger, F; Seeger, W; Walmrath, D Zardaverine and aerosolised iloprost in a model of acute respiratory failure.
Eur Respir J. 2003; 22(2):342-347 [OPEN ACCESS]
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Wakabayashi, I; Groschner, K Vascular actions of anthracycline antibiotics.
Curr Med Chem. 2003; 10(5):427-436
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2002

Gessler, T; Schmehl, T; Olschewski, H; Grimminger, F; Seeger, W Aerosolized vasodilators in pulmonary hypertension.
J Aerosol Med. 2002; 15(2):117-122
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Ghofrani, HA; Wiedemann, R; Rose, F; Olschewski, H; Schermuly, RT; Weissmann, N; Seeger, W; Grimminger, F Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension.
Ann Intern Med. 2002; 136(7):515-522 [OPEN ACCESS]
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Ghofrani, HA; Wiedemann, R; Rose, F; Schermuly, RT; Olschewski, H; Weissmann, N; Gunther, A; Walmrath, D; Seeger, W; Grimminger, F Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial.
Lancet. 2002; 360(9337):895-900
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Olschewski, H; Simonneau, G; Galiè, N; Higenbottam, T; Naeije, R; Rubin, LJ; Nikkho, S; Speich, R; Hoeper, MM; Behr, J; Winkler, J; Sitbon, O; Popov, W; Ghofrani, HA; Manes, A; Kiely, DG; Ewert, R; Meyer, A; Corris, PA; Delcroix, M; Gomez-Sanchez, M; Siedentop, H; Seeger, W; Aerosolized Iloprost Randomized Study Group Inhaled iloprost for severe pulmonary hypertension.
N Engl J Med. 2002; 347(5):322-329 [OPEN ACCESS]
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2001

Beinder, E; Scalera, F; Schlembach, D Influence of reduced intracellular glutathione availability on the secretion of vasoactive substances by human umbilical vein endothelial cells.
Hypertens Pregnancy. 2001; 20(1):45-56
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Brodmann, M; Stelzer, I; Friedl, M; Lueger, A; Pilger, E; Stark, G Comparison of the Effect of Prostaglandin E(1), Prostacycline and Adenosine on Peripheral Vascular Resistance.
Int. J. Angiol.. 2001; 10(1): 31-33.
PubMed

 

Gessler, T; Schmehl, T; Hoeper, MM; Rose, F; Ghofrani, HA; Olschewski, H; Grimminger, F; Seeger, W Ultrasonic versus jet nebulization of iloprost in severe pulmonary hypertension.
Eur Respir J. 2001; 17(1):14-19 [OPEN ACCESS]
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Olschewski, H; Rose, F; Grünig, E; Ghofrani, HA; Walmrath, D; Schulz, R; Schermuly, R; Grimminger, F; Seeger, W Cellular pathophysiology and therapy of pulmonary hypertension.
J Lab Clin Med. 2001; 138(6):367-377
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Scalera, F; Schlembach, D; Beinder, E Production of vasoactive substances by human umbilical vein endothelial cells after incubation with serum from preeclamptic patients.
Eur J Obstet Gynecol Reprod Biol. 2001; 99(2):172-178
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2000

Grimminger, F; Rose, F; Ghofrani, HA; Schermuly, RT; Weissmann, N; Olschewski, H; Walmrath, D; Seeger, W Inhalative strategies for improvement of pulmonary hemodynamics and gas exchange in sepsis and severe pulmonary hypertension
Z Kardiol. 2000; 89(6):477-484
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Hoeper, MM; Olschewski, H; Ghofrani, HA; Wilkens, H; Winkler, J; Borst, MM; Niedermeyer, J; Fabel, H; Seeger, W A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group.
J Am Coll Cardiol. 2000; 35(1):176-182 [OPEN ACCESS]
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Olschewski, H; Ghofrani, HA; Schmehl, T; Winkler, J; Wilkens, H; Höper, MM; Behr, J; Kleber, FX; Seeger, W Inhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial. German PPH Study Group.
Ann Intern Med. 2000; 132(6):435-443 [OPEN ACCESS]
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1999

Olschewski, H; Ghofrani, HA; Walmrath, D; Schermuly, R; Temmesfeld-Wollbruck, B; Grimminger, F; Seeger, W Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis.
Am J Respir Crit Care Med. 1999; 160(2):600-607 [OPEN ACCESS]
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1998

Bonatti, J; Dichtl, W; Dworzak, EA; Antretter, H; Unger, F; Puschendorf, B; Dapunt, OE Atrial natriuretic peptide-induced release of cyclic guanosine monophosphate by coronary bypass grafts.
Ann Thorac Surg. 1998; 65(6):1621-1624
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Bonatti, J; Dichtl, W; Dworzak, EA; Antretter, H; Unger, F; Puschendorf, B; Dapunt, OE Stimulated prostacyclin release by conduits used for coronary artery bypass grafting.
Thorac Cardiovasc Surg. 1998; 46(2):59-62
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