Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: P53, . Treffer: 148

2019

Papuc, SM; Abela, L; Steindl, K; Begemann, A; Simmons, TL; Schmitt, B; Zweier, M; Oneda, B; Socher, E; Crowther, LM; Wohlrab, G; Gogoll, L; Poms, M; Seiler, M; Papik, M; Baldinger, R; Baumer, A; Asadollahi, R; Kroell-Seger, J; Schmid, R; Iff, T; Schmitt-Mechelke, T; Otten, K; Hackenberg, A; Addor, MC; Klein, A; Azzarello-Burri, S; Sticht, H; Joset, P; Plecko, B; Rauch, A The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study.
Eur J Hum Genet. 2019; 27(3):408-421
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Prochazka, KT; Pregartner, G; Rücker, FG; Heitzer, E; Pabst, G; Wölfler, A; Zebisch, A; Berghold, A; Döhner, K; Sill, H Clinical implications of subclonal TP53 mutations in acute myeloid leukemia.
Haematologica. 2019; 104(3):516-523 [OPEN ACCESS]
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Regauer, S; Kashofer, K; Reich, O Time series analysis of TP53 gene mutations in recurrent HPV-negative vulvar squamous cell carcinoma
MODERN PATHOL. 2019; 32(3): 415-422.
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Richtig, G; Aigelsreiter, AM; Asslaber, M; Weiland, T; Pichler, M; Eberhard, K; Sygulla, S; Schauer, S; Hoefler, G; Aigelsreiter, A Hedgehog pathway proteins SMO and GLI expression as prognostic marker in head and neck squamous cell carcinoma - a retrospective immunohistochemical study.
Histopathology. 2019;
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2018

Al-Zoughbi, W; Schauer, S; Pichler, M; Hoefler, G Early Loss of Forkhead Transcription Factor, O Subgroup, Member 1 Protein in the Development of Pancreatic Ductal Adenocarcinoma.
Pathobiology. 2018; 85(5-6): 342-347. [OPEN ACCESS]
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Bourgeois, B; Madl, T Regulation of cellular senescence via the FOXO4-p53 axis.
FEBS LETT. 2018; 592(12): 2083-2097. [OPEN ACCESS]
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Gauster, M; Maninger, S; Siwetz, M; Deutsch, A; El-Heliebi, A; Kolb-Lenz, D; Hiden, U; Desoye, G; Herse, F; Prokesch, A Downregulation of p53 drives autophagy during human trophoblast differentiation.
Cell Mol Life Sci. 2018; 75(10):1839-1855 [OPEN ACCESS]
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Griewank, KG; Wiesner, T; Murali, R; Pischler, C; Müller, H; Koelsche, C; Möller, I; Franklin, C; Cosgarea, I; Sucker, A; Schadendorf, D; Schaller, J; Horn, S; Brenn, T; Mentzel, T Atypical fibroxanthoma and pleomorphic dermal sarcoma harbor frequent NOTCH1/2 and FAT1 mutations and similar DNA copy number alteration profiles.
Mod Pathol. 2018; 31(3): 418-428.
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Heil, J; Schultze, D; Schemmer, P; Bruns, H N-acetylcysteine protects hepatocytes from hypoxia-related cell injury.
Clin Exp Hepatol. 2018; 4(4): 260-266. [OPEN ACCESS]
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Hofving, T; Arvidsson, Y; Almobarak, B; Inge, L; Pfragner, R; Persson, M; Stenman, G; Kristiansson, E; Johanson, V; Nilsson, O The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
ENDOCR-RELAT CANCER. 2018; 25(3): 367-380. [OPEN ACCESS]
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Kindler, O; Quehenberger, F; Benesch, M; Seidel, MG The Iceberg Map of germline mutations in childhood cancer: focus on primary immunodeficiencies.
Curr Opin Pediatr. 2018; 30(6):855-863
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Krstic, J; Galhuber, M; Schulz, TJ; Schupp, M; Prokesch, A p53 as a Dichotomous Regulator of Liver Disease: The Dose Makes the Medicine.
Int J Mol Sci. 2018; 19(3): [OPEN ACCESS]
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Krstic, J; Reinisch, I; Schupp, M; Schulz, TJ; Prokesch, A p53 Functions in Adipose Tissue Metabolism and Homeostasis
INT J MOL SCI. 2018; 19(9): 2622 [OPEN ACCESS]
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Markoš, P; Brčić, I; Brčić, L; Jakić-Razumović, J; Pulanić, R Microsatellite instability in metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus: a retrospective study.
Croat Med J. 2018; 59(3): 100-107. [OPEN ACCESS]
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Morshaeuser, L; May, M; Burger, M; Otto, W; Hutterer, GC; Pichler, M; Klatte, T; Wild, P; Buser, L; Brookman-May, S p53-expression in patients with renal cell carcinoma correlates with a higher probability of disease progression and increased cancer-specific mortality after surgery but does not enhance the predictive accuracy of robust outcome models.
Urol Oncol. 2018; 36(3):94.e15-94.e94
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Schulz, E; Lind, K; Renner, W; Petersen, BS; Quehenberger, F; Dill, C; Hofer, S; Lal, R; Hoefler, G; Schlenke, P; Ehninger, G; Schetelig, J; Middeke, JM; Stölzel, F; Sill, H The TP53 Pro72Arg SNP in de novo acute myeloid leukaemia - results of two cohort studies involving 215 patients and 3759 controls.
Br J Haematol. 2018; 181(1):148-151
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2017

Baar, MP; Brandt, RMC; Putavet, DA; Klein, JDD; Derks, KWJ; Bourgeois, BRM; Stryeck, S; Rijksen, Y; van Willigenburg, H; Feijtel, DA; van der Pluijm, I; Essers, J; van Cappellen, WA; van IJcken, WF; Houtsmuller, AB; Pothof, J; de Bruin, RWF; Madl, T; Hoeijmakers, JHJ; Campisi, J; de Keizer, PLJ Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Cell. 2017; 169(1):132-147 [OPEN ACCESS]
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Ebai, T; Souza de Oliveira, FM; Löf, L; Wik, L; Schweiger, C; Larsson, A; Keilholtz, U; Haybaeck, J; Landegren, U; Kamali-Moghaddam, M Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.
Clin Chem. 2017; 63(9):1497-1505 [OPEN ACCESS]
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González-Vela, MDC; Curiel-Olmo, S; Derdak, S; Beltran, S; Santibañez, M; Martínez, N; Castillo-Trujillo, A; Gut, M; Sánchez-Pacheco, R; Almaraz, C; Cereceda, L; Llombart, B; Agraz-Doblas, A; Revert-Arce, J; López Guerrero, JA; Mollejo, M; Marrón, PI; Ortiz-Romero, P; Fernandez-Cuesta, L; Varela, I; Gut, I; Cerroni, L; Piris, MÁ; Vaqué, JP Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas.
J Invest Dermatol. 2017; 137(1):197-206 [OPEN ACCESS]
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Heitzer, E; Sunitsch, S; Gilg, MM; Lohberger, B; Rinner, B; Kashofer, K; Stündl, N; Ulz, P; Szkandera, J; Leithner, A; Liegl-Atzwanger, B Expanded molecular profiling of myxofibrosarcoma reveals potentially actionable targets.
Mod Pathol. 2017; 30(12):1698-1709 [OPEN ACCESS]
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Kashofer, K; Regauer, S Analysis of full coding sequence of the TP53 gene in invasive vulvar cancers: Implications for therapy.
GYNECOL ONCOL. 2017; 146(2): 314-318.
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Kashofer, K; Winter, E; Halbwedl, I; Thueringer, A; Kreiner, M; Sauer, S; Regauer, S HPV-negative penile squamous cell carcinoma: disruptive mutations in the TP53 gene are common.
Mod Pathol. 2017; 30(7):1013-1020 [OPEN ACCESS]
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Lax, SF Pathology of Endometrial Carcinoma.
Adv Exp Med Biol. 2017; 943(4):75-96
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Lienhart, WD; Strandback, E; Gudipati, V; Koch, K; Binter, A; Uhl, MK; Rantasa, DM; Bourgeois, B; Madl, T; Zangger, K; Gruber, K; Macheroux, P Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1).
FEBS J. 2017; 284(8): 1233-1245. [OPEN ACCESS]
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Lohberger, B; Stuendl, N; Leithner, A; Rinner, B; Sauer, S; Kashofer, K; Liegl-Atzwanger, B Establishment of a novel cellular model for myxofibrosarcoma heterogeneity.
Sci Rep. 2017; 7(9):44700-44700 [OPEN ACCESS]
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 [OPEN ACCESS]
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Schuoler, C; Haider, TJ; Leuenberger, C; Vogel, J; Ostergaard, L; Kwapiszewska, G; Kohler, M; Gassmann, M; Huber, LC; Brock, M Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension.
Basic Res Cardiol. 2017; 112(3): 30-30.
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Weyerer, V; Schneckenpointner, R; Filbeck, T; Burger, M; Hofstaedter, F; Wild, PJ; Fine, SW; Humphrey, PA; Dehner, LP; Amin, MB; Rüschoff, J; Boltze, C; Tannapfel, A; Zwarthoff, E; Lopez-Beltran, A; Montironi, R; Langner, C; Stoehr, R; Hartmann, A; Giedl, J Immunohistochemical and molecular characterizations in urothelial carcinoma of bladder in patients less than 45 years.
J Cancer. 2017; 8(3):323-331 [OPEN ACCESS]
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2016

Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
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Busch, SE; Hanke, ML; Kargl, J; Metz, HE; MacPherson, D; Houghton, AM Lung Cancer Subtypes Generate Unique Immune Responses.
J Immunol. 2016; 197(11):4493-4503 [OPEN ACCESS]
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Fröhlich, LF; Mrakovcic, M; Smole, C; Zatloukal, K Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway.
Cancer Cell Int. 2016; 16(1):68-68 [OPEN ACCESS]
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Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
Biochem Pharmacol. 2016; 104:29-41 [OPEN ACCESS]
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Lax, SF [New features in the 2014 WHO classification of uterine neoplasms].
Pathologe. 2016; 37(6):500-511 [OPEN ACCESS]
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Lax, SF; Tamussino, KF; Lang, PF [Metastatic mechanisms of uterine malignancies and therapeutic consequences].
Pathologe. 2016; 37(6):549-556 [OPEN ACCESS]
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Regauer, S; Eberz, B; Reich, O Human Papillomavirus-Induced Squamous Intraepithelial Lesions in Vulvar Lichen Planus.
J Low Genit Tract Dis. 2016; 20(4):360-364
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Sigl, V; Owusu-Boaitey, K; Joshi, PA; Kavirayani, A; Wirnsberger, G; Novatchkova, M; Kozieradzki, I; Schramek, D; Edokobi, N; Hersl, J; Sampson, A; Odai-Afotey, A; Lazaro, C; Gonzalez-Suarez, E; Pujana, MA; Cimba, F; Heyn, H; Vidal, E; Cruickshank, J; Berman, H; Sarao, R; Ticevic, M; Uribesalgo, I; Tortola, L; Rao, S; Tan, Y; Pfeiler, G; Lee, EY; Bago-Horvath, Z; Kenner, L; Popper, H; Singer, C; Khokha, R; Jones, LP; Penninger, JM RANKL/RANK control Brca1 mutation- .
Cell Res. 2016; 26(7):761-774 [OPEN ACCESS]
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von Bueren, AO; Kortmann, RD; von Hoff, K; Friedrich, C; Mynarek, M; Müller, K; Goschzik, T; Zur Mühlen, A; Gerber, N; Warmuth-Metz, M; Soerensen, N; Deinlein, F; Benesch, M; Zwiener, I; Kwiecien, R; Faldum, A; Bode, U; Fleischhack, G; Hovestadt, V; Kool, M; Jones, D; Northcott, P; Kuehl, J; Pfister, S; Pietsch, T; Rutkowski, S Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters.
J Clin Oncol. 2016; 34(34):4151-4160
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Zhang, F; Li, M; Su, Y; Zhou, J; Wang, W A dual-targeting drug co-delivery system for tumor chemo- and gene combined therapy.
Mater Sci Eng C Mater Biol Appl. 2016; 64(28): 208-218.
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2015

Bernhart, E; Damm, S; Wintersperger, A; Nusshold, C; Brunner, AM; Plastira, I; Rechberger, G; Reicher, H; Wadsack, C; Zimmer, A; Malle, E; Sattler, W Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.
Biochem Pharmacol. 2015; 96(2): 119-130. [OPEN ACCESS]
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Fischer, C; Scheipl, S; Zopf, A; Niklas, N; Deutsch, A; Jorgensen, M; Lohberger, B; Froehlich, EV; Leithner, A; Gabriel, C; Liegl-Atzwanger, B; Rinner, B Mutation Analysis of Nine Chordoma Specimens by Targeted Next-Generation Cancer Panel Sequencing.
J Cancer. 2015; 6(10):984-989 [OPEN ACCESS]
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Jahn, SW; Kashofer, K; Halbwedl, I; Winter, G; El-Shabrawi-Caelen, L; Mentzel, T; Hoefler, G; Liegl-Atzwanger, B Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.
Mod Pathol. 2015; 28(7):895-903 [OPEN ACCESS]
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Kandioler, D; Mittlböck, M; Kappel, S; Puhalla, H; Herbst, F; Langner, C; Wolf, B; Tschmelitsch, J; Schippinger, W; Steger, G; Hofbauer, F; Samonigg, H; Gnant, M; Teleky, B; Kührer, I; p53 Research Group and the Austrian Breast and Colorectal Study Group (ABCSG) TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients.
EBioMedicine. 2015; 2(8):825-830 [OPEN ACCESS]
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Meena, JK; Cerutti, A; Beichler, C; Morita, Y; Bruhn, C; Kumar, M; Kraus, JM; Speicher, MR; Wang, ZQ; Kestler, HA; d'Adda di Fagagna, F; Günes, C; Rudolph, KL Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.
EMBO J. 2015; 34(10):1371-1384 [OPEN ACCESS]
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Murali, R; Chandramohan, R; Möller, I; Scholz, SL; Berger, M; Huberman, K; Viale, A; Pirun, M; Socci, ND; Bouvier, N; Bauer, S; Artl, M; Schilling, B; Schimming, T; Sucker, A; Schwindenhammer, B; Grabellus, F; Speicher, MR; Schaller, J; Hillen, U; Schadendorf, D; Mentzel, T; Cheng, DT; Wiesner, T; Griewank, KG Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.
Oncotarget. 2015; 6(34):36041-36052 [OPEN ACCESS]
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Saternus, R; Pilz, S; Gräber, S; Kleber, M; März, W; Vogt, T; Reichrath, J A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration.
Endocrinology. 2015; 156(1):39-47 [OPEN ACCESS]
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Schulz, E; Kashofer, K; Heitzer, E; Mhatre, KN; Speicher, MR; Hoefler, G; Sill, H Preexisting TP53 mutation in therapy-related acute myeloid leukemia.
Ann Hematol. 2015; 94(3):527-529 (- Case Report) [OPEN ACCESS]
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Zuckermann, M; Hovestadt, V; Knobbe-Thomsen, CB; Zapatka, M; Northcott, PA; Schramm, K; Belic, J; Jones, DT; Tschida, B; Moriarity, B; Largaespada, D; Roussel, MF; Korshunov, A; Reifenberger, G; Pfister, SM; Lichter, P; Kawauchi, D; Gronych, J Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.
Nat Commun. 2015; 6(3):7391-7391 [OPEN ACCESS]
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2014

Aigelsreiter, AM; Aigelsreiter, A; Wehrschuetz, M; Ress, AL; Koller, K; Salzwimmer, M; Gerger, A; Schauer, S; Bauernhofer, T; Pichler, M Loss of the putative tumor suppressor protein spinophilin is associated with poor prognosis in head and neck cancer.
Hum Pathol. 2014; 45(4):683-690
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Beer, L; Seemann, R; Ristl, R; Ellinger, A; Kasiri, MM; Mitterbauer, A; Zimmermann, M; Gabriel, C; Gyöngyösi, M; Klepetko, W; Mildner, M; Ankersmit, HJ High dose ionizing radiation regulates micro RNA and gene expression changes in human peripheral blood mononuclear cells.
BMC Genomics. 2014; 15(10):814-814 [OPEN ACCESS]
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Bernhart, E; Damm, S; Heffeter, P; Wintersperger, A; Asslaber, M; Frank, S; Hammer, A; Strohmaier, H; DeVaney, T; Mrfka, M; Eder, H; Windpassinger, C; Ireson, CR; Mischel, PS; Berger, W; Sattler, W Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.
Neuro Oncol. 2014; 16(7):933-945 [OPEN ACCESS]
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