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Publikationen

Suchbegriffe: OLIGOMERS, . Treffer: 31

2022

Ring, J; Tadic, J; Ristic, S; Poglitsch, M; Bergmann, M; Radic, N; Mossmann, D; Liang, YT; Maglione, M; Jerkovic, A; Hajiraissi, R; Hanke, M; Kuttner, V; Wolinski, H; Zimmermann, A; Trifunovic, LD; Mikolasch, L; Moretti, DN; Broeskamp, F; Westermayer, J; Abraham, C; Schauer, S; Dammbrueck, C; Hofer, SJ; Abdellatif, M; Grundmeier, G; Kroemer, G; Braun, RJ; Hansen, N; Sommer, C; Ninkovic, M; Seba, S; Rockenfeller, P; Vogtle, FN; Dengjel, J; Meisinger, C; Keller, A; Sigrist, SJ; Eisenberg, T; Madeo, F The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity
EMBO MOL MED. 2022; e13952 Doi: 10.15252/emmm.202113952 [OPEN ACCESS]
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2021

Alderson, TR; Adriaenssens, E; Asselbergh, B; Pritišanac, I; Van, Lent, J; Gastall, HY; Wälti, MA; Louis, JM; Timmerman, V; Baldwin, AJ; Lp, Benesch, J A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
EMBO J. 2021; 40(8):e103811 Doi: 10.15252/embj.2019103811 [OPEN ACCESS]
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Dengler, MA; Gibson, L; Adams, JM BAX mitochondrial integration is regulated allosterically by its α1-α2 loop.
Cell Death Differ. 2021; 28(12):3270-3281 Doi: 10.1038/s41418-021-00815-x [OPEN ACCESS]
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2020

Alderson, TR; Kay, LE Unveiling invisible protein states with NMR spectroscopy.
Curr Opin Struct Biol. 2020; 60: 39-49. Doi: 10.1016/j.sbi.2019.10.008
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Alderson, TR; Ying, J; Bax, A; Benesch, JLP; Baldwin, AJ Conditional Disorder in Small Heat-shock Proteins.
J Mol Biol. 2020; 432(9): 3033-3049. Doi: 10.1016/j.jmb.2020.02.003 [OPEN ACCESS]
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Silbernagel, G; Scharnagl, H; Kleber, ME; Hoffmann, MM; Delgado, G; Stojakovic, T; Gary, T; Zeng, L; Ritsch, A; Zewinger, S; Speer, T; Schunkert, H; Landmesser, U; März, W; Grammer, TB, ;Meta-Analyses, of, Glucose, and, Insulin-related, traits, Consortium, (MAGIC);Meta-Analyses, of, Glucose, and, Insulin-related, traits, Consortium, (MAGIC) Common APOC3 variants are associated with circulating ApoC-III and VLDL cholesterol but not with total apolipoprotein B and coronary artery disease.
Atherosclerosis. 2020; 311:84-90 Doi: 10.1016/j.atherosclerosis.2020.08.017
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2019

Ablasser, K; Verheyen, N; Glantschnig, T; Agnetti, G; Rainer, PP Unfolding Cardiac Amyloidosis -From Pathophysiology to Cure.
Curr Med Chem. 2019; 26(16):2865-2878 Doi: 10.2174/0929867325666180104153338
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Alderson, TR; Roche, J; Gastall, HY; Dias, DM; Pritišanac, I; Ying, J; Bax, A; Benesch, JLP; Baldwin, AJ Local unfolding of the HSP27 monomer regulates chaperone activity.
Nat Commun. 2019; 10(1):1068 Doi: 10.1038/s41467-019-08557-8 [OPEN ACCESS]
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Butorac, C; Muik, M; Derler, I; Stadlbauer, M; Lunz, V; Krizova, A; Lindinger, S; Schober, R; Frischauf, I; Bhardwaj, R; Hediger, MA; Groschner, K; Romanin, C A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
CELL CALCIUM. 2019; 79(6): 57-67. Doi: 10.1016/j.ceca.2019.02.009 [OPEN ACCESS]
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Dengler, MA; Robin, AY; Gibson, L; Li, MX; Sandow, JJ; Iyer, S; Webb, AI; Westphal, D; Dewson, G; Adams, JM BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association.
Cell Rep. 2019; 27(2):359-373 Doi: 10.1016/j.celrep.2019.03.040
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Fanaee-Danesh, E; Gali, CC; Tadic, J; Zandl-Lang, M; Carmen Kober, A; Agujetas, VR; de Dios, C; Tam-Amersdorfer, C; Stracke, A; Albrecher, NM; Manavalan, APC; Reiter, M; Sun, Y; Colell, A; Madeo, F; Malle, E; Panzenboeck, U Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(9): 2224-2245. Doi: 10.1016/j.bbadis.2019.04.019 [OPEN ACCESS]
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Maki, RA; Holzer, M; Motamedchaboki, K; Malle, E; Masliah, E; Marsche, G; Reynolds, WF Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.
Free Radic Biol Med. 2019; 141:115-140 Doi: 10.1016/j.freeradbiomed.2019.05.033 [OPEN ACCESS]
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2018

Cristóvão, JS; Morris, VK; Cardoso, I; Leal, SS; Martínez, J; Botelho, HM; Göbl, C; David, R; Kierdorf, K; Alemi, M; Madl, T; Fritz, G; Reif, B; Gomes, CM The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation.
SCI ADV. 2018; 4(6): eaaq1702-eaaq1702. Doi: 10.1126/sciadv.aaq1702 [OPEN ACCESS]
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Omtri, RS; Thompson, KJ; Tang, X; Gali, CC; Panzenboeck, U; Davidson, MW; Kalari, KR; Kandimalla, KK Differential Effects of Alzheimer's Disease Aβ40 and 42 on Endocytosis and Intraneuronal Trafficking.
Neuroscience. 2018; 373(3 Suppl 2):159-168 Doi: 10.1016/j.neuroscience.2018.01.003
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Rainer, PP; Dong, P; Sorge, M; Fert-Bober, J; Holewinski, RJ; Wang, Y; Foss, CA; An, SS; Baracca, A; Solaini, G; Glabe, CG; Pomper, MG; Van Eyk, JE; Tomaselli, GF; Paolocci, N; Agnetti, G Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure.
Circ Res. 2018; 122(10): e75-e83-e75-e83. Doi: 10.1161/CIRCRESAHA.117.312082 [OPEN ACCESS]
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Zandl-Lang, M; Fanaee-Danesh, E; Sun, Y; Albrecher, NM; Gali, CC; Čančar, I; Kober, A; Tam-Amersdorfer, C; Stracke, A; Storck, SM; Saeed, A; Stefulj, J; Pietrzik, CU; Wilson, MR; Björkhem, I; Panzenboeck, U Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Biochim Biophys Acta Mol Cell Biol Lipids. 2018; 1863(1):40-60 Doi: 10.1016/j.bbalip.2017.09.008
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2017

Alderson, TR; Benesch, JLP; Baldwin, AJ Proline isomerization in the C-terminal region of HSP27.
Cell Stress Chaperones. 2017; 22(4): 639-651. Doi: 10.1007/s12192-017-0791-z [OPEN ACCESS]
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2015

Rainer, P; Lee, DI; Sorge, M; Guarnieri, C; Glabe, CG; O'Rourke, B; Tomaselli, GF; Kass, DA; Van Eyk, JE; Agnetti, G Desmin Preamyloid Oligomers in Experimental Heart Failure and Cultured Cardiac Myocytes
CIRC RES. 2015; 117:
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Wang, T; Grabski, R; Sztul, E; Hay, JC p115-SNARE interactions: a dynamic cycle of p115 binding monomeric SNARE motifs and releasing assembled bundles.
Traffic. 2015; 16(2):148-171 Doi: 10.1111/tra.12242 [OPEN ACCESS]
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2014

Deak, AT; Blass, S; Khan, MJ; Groschner, LN; Waldeck-Weiermair, M; Hallström, S; Graier, WF; Malli, R IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake.
J Cell Sci. 2014; 127(Pt 13):2944-2955 Doi: 10.1242/jcs.149807 [OPEN ACCESS]
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Löffler, T; Flunkert, S; Havas, D; Schweinzer, C; Uger, M; Windisch, M; Steyrer, E; Hutter-Paier, B Neuroinflammation and related neuropathologies in APPSL mice: further value of this in vivo model of Alzheimer's disease.
J Neuroinflammation. 2014; 11(7):84-84 Doi: 10.1186/1742-2094-11-84 [OPEN ACCESS]
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2013

Hofrichter, J; Krohn, M; Schumacher, T; Lange, C; Feistel, B; Walbroel, B; Heinze, HJ; Crockett, S; Sharbel, TF; Pahnke, J Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice.
Curr Alzheimer Res. 2013; 10(10):1057-1069 Doi: 10.2174/15672050113106660171 [OPEN ACCESS]
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2011

Schweinzer, C; Kober, A; Lang, I; Etschmaier, K; Scholler, M; Kresse, A; Sattler, W; Panzenboeck, U Processing of endogenous AβPP in blood-brain barrier endothelial cells is modulated by liver-X receptor agonists and altered cellular cholesterol homeostasis.
J Alzheimers Dis. 2011; 27(2):341-360 Doi: 10.3233/JAD-2011-110854
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2009

Müllner, C; Steinecker, B; Gorischek, A; Schreibmayer, W Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase.
FEBS J. 2009; 276(21): 6218-6226. Doi: 10.1111/j.1742-4658.2009.07325.x [OPEN ACCESS]
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Schicker, K; Hussl, S; Chandaka, GK; Kosenburger, K; Yang, JW; Waldhoer, M; Sitte, HH; Boehm, S A membrane network of receptors and enzymes for adenine nucleotides and nucleosides.
Biochim Biophys Acta. 2009; 1793(2): 325-334. Doi: 10.1016/j.bbamcr.2008.09.014 [OPEN ACCESS]
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2008

Malli, R; Naghdi, S; Romanin, C; Graier, WF Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload.
J Cell Sci. 2008; 121(Pt 19): 3133-3139. Doi: 10.1242/jcs.034496 [OPEN ACCESS]
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2002

Maier, A; Tomaselli, F; Matzi, V; Woltsche, M; Anegg, U; Fell, B; Rehak, P; Pinter, H; Smolle-Jüttner, FM Comparison of 5-aminolaevulinic acid and porphyrin photosensitization for photodynamic therapy of malignant bronchial stenosis: a clinical pilot study.
Lasers Surg Med. 2002; 30(1):12-17 Doi: 10.1002%2Flsm.10009
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2001

Eder, K; Sinner, F; Mupa, M; Huber, CG; Buchmeiser, MR Evaluation of norbornene- beta-cyclodextrin-based monomers and oligomers as chiral selectors by means of nonaqueous capillary electrophoresis.
Electrophoresis. 2001; 22(1):109-116 Doi: 10.1002/1522-2683(200101)22:1<109::AID-ELPS109>3.0.CO;2-P
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2000

Lintschinger, B; Balzer-Geldsetzer, M; Baskaran, T; Graier, WF; Romanin, C; Zhu, MX; Groschner, K Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels.
J Biol Chem. 2000; 275(36):27799-27805 Doi: 10.1074/jbc.M002705200 [OPEN ACCESS]
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1999

Bark, N; Földes-Papp, Z; Rigler, R The incipient stage in thrombin-induced fibrin polymerization detected by FCS at the single molecule level.
Biochem Biophys Res Commun. 1999; 260(1): 35-41. Doi: 10.1006/bbrc.1999.0850
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1997

Westra, DF; Glazenburg, KL; Harmsen, MC; Tiran, A; Jan Scheffer, A; Welling, GW; Hauw The, T; Welling-Wester, S Glycoprotein H of herpes simplex virus type 1 requires glycoprotein L for transport to the surfaces of insect cells.
J Virol. 1997; 71(3): 2285-2291. Doi: 10.1128/JVI.71.3.2285-2291.1997 [OPEN ACCESS]
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