Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: NEXT-GENERATION SEQUENCING, . Treffer: 102

2023

Brcic, I; Kluba, AM; Godschachner, TM; Suppan, C; Regitnig, P; Dandachi, N; Lax, SF; Balić, M Tumor Microenvironment in Male Breast Carcinoma with Emphasis on Tumor Infiltrating Lymphocytes and PD-L1 Expression.
Int J Mol Sci. 2023; 24(1): Doi: 10.3390/ijms24010818 [OPEN ACCESS]
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Dai, Q; Zhang, J; Long, W; Haybaeck, J; Yang, Z Genetic alterations of GI-NECs involving three main signaling pathways.
Cancer Med. 2023; Doi: 10.1002/cam4.5633
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Hoenigl, M; Egger, M; Price, J; Krause, R; Prattes, J; White, PL Metagenomic Next-Generation Sequencing of Plasma for Diagnosis of COVID-19-Associated Pulmonary Aspergillosis.
J Clin Microbiol. 2023; e0185922 Doi: 10.1128/jcm.01859-22
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Zandl-Lang, M; Plecko, B; Köfeler, H Lipidomics-Paving the Road towards Better Insight and Precision Medicine in Rare Metabolic Diseases.
Int J Mol Sci. 2023; 24(2): Doi: 10.3390/ijms24021709 [OPEN ACCESS]
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2022

Boos, SL; Loevenich, LP; Vosberg, S; Engleitner, T; Öllinger, R; Kumbrink, J; Rokavec, M; Michl, M; Greif, PA; Jung, A; Hermeking, H; Neumann, J; Kirchner, T; Rad, R; Jung, P Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
Cell Mol Gastroenterol Hepatol. 2022; 13(2): 517-540. Doi: 10.1016/j.jcmgh.2021.10.008 [OPEN ACCESS]
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Dutta, S; Moritz, J; Pregartner, G; Thallinger, GG; Brandstätter, I; Lind, K; Rezania, S; Lyssy, F; Reinisch, A; Zebisch, A; Berghold, A; Wölfler, A; Sill, H Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations.
Ann Hematol. 2022; 101(4):837-846 Doi: 10.1007/s00277-022-04766-2 [OPEN ACCESS]
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Eisenhardt, AE; Brugger, Z; Lausch, U; Kiefer, J; Zeller, J; Runkel, A; Schmid, A; Bronsert, P; Wehrle, J; Leithner, A; Liegl-Atzwanger, B; Giunta, RE; Eisenhardt, SU; Braig, D Genotyping of Circulating Free DNA Enables Monitoring of Tumor Dynamics in Synovial Sarcomas.
Cancers (Basel). 2022; 14(9): 2078 Doi: 10.3390/cancers14092078 [OPEN ACCESS]
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Eisenhardt, AE; Schmid, A; Esser, J; Brugger, Z; Lausch, U; Kiefer, J; Braig, M; Runkel, A; Wehrle, J; Claus, R; Bronsert, P; Leithner, A; Liegl-Atzwanger, B; Zeller, J; Papini, R; von, Laffert, M; Pfitzner, BM; Koulaxouzidis, G; Giunta, RE; Eisenhardt, SU; Braig, D Targeted next-generation sequencing of circulating free DNA enables non-invasive tumor detection in myxoid liposarcomas.
Mol Cancer. 2022; 21(1): 50 Doi: 10.1186/s12943-022-01523-x [OPEN ACCESS]
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Feng, J; Li, Y; Wei, B; Guo, L; Li, W; Xia, Q; Zhao, C; Zheng, J; Zhao, J; Sun, R; Guo, Y; Brcic, L; Hakozaki, T; Ying, J; Ma, J Clinicopathologic characteristics and diagnostic methods of RET rearrangement in Chinese non-small cell lung cancer patients.
Transl Lung Cancer Res. 2022; 11(4): 617-631. Doi: 10.21037/tlcr-22-202 [OPEN ACCESS]
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Hasenleithner, SO; Speicher, MR A clinician's handbook for using ctDNA throughout the patient journey.
Mol Cancer. 2022; 21(1): 81 Doi: 10.1186/s12943-022-01551-7 [OPEN ACCESS]
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Jahn, SW; Jost, PJ Challenges in integrating molecular profiles into clinical cancer care
MEMO-MAG EUR MED ONC. 2022; Doi: 10.1007/s12254-022-00838-1
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Krenn, M; Tomschik, M; Wagner, M; Zulehner, G; Weng, R; Rath, J; Klotz, S; Gelpi, E; Bsteh, G; Keritam, O; Colonna, I; Paternostro, C; Jäger, F; Lindeck-Pozza, E; Iglseder, S; Grinzinger, S; Schönfelder, M; Hohenwarter, C; Freimüller, M; Embacher, N; Wanschitz, J; Topakian, R; Töpf, A; Straub, V; Quasthoff, S; Zimprich, F; Löscher, WN; Cetin, H Clinico-genetic spectrum of limb-girdle muscular weakness in Austria: A multicentre cohort study.
Eur J Neurol. 2022; 29(6):1815-1824 Doi: 10.1111/ene.15306 [OPEN ACCESS]
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Schaflinger, E; Enko, D [The Impact of Next-Generation Sequencing on Medical Genetic Diagnostics and Counseling].
Dtsch Med Wochenschr. 2022; 147(20): 1336-1341. Doi: 10.1055/a-1924-6646
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Schulz, E; Grumaz, S; Hatzl, S; Gornicec, M; Valentin, T; Huber-Kraßnitzer, B; Kriegl, L; Uhl, B; Deutsch, A; Greinix, H; Krause, R; Neumeister, P Pathogen Detection by Metagenomic Next-Generation Sequencing During Neutropenic Fever in Patients With Hematological Malignancies.
Open Forum Infect Dis. 2022; 9(8): ofac393 Doi: 10.1093/ofid/ofac393 [OPEN ACCESS]
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Steiner, D; Smolle, MA; Brcic, I; Leithner, A Rhabdomyosarcoma and pleomorphic sarcoma in the same location : Recurrence or new entity?
Wien Klin Wochenschr. 2022; 134(1-2):76-79 Doi: 10.1007/s00508-021-01872-5 [OPEN ACCESS]
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Tsybrovskyy, O; De, Luise, M; de, Biase, D; Caporali, L; Fiorini, C; Gasparre, G; Carelli, V; Hackl, D; Imamovic, L; Haim, S; Sobrinho-Simões, M; Tallini, G Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors.
J Pathol Clin Res. 2022; 8(2):155-168 Doi: 10.1002/cjp2.247 [OPEN ACCESS]
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2021

Angus, L; Deger, T; Jager, A; Martens, JWM; de, Weerd, V; van, Heuvel, I; van, den, Bent, MJ; Sillevis, Smitt, PAE; Kros, JM; Bindels, EMJ; Heitzer, E; Sleijfer, S; Jongen, JLM; Wilting, SM Detection of Aneuploidy in Cerebrospinal Fluid from Patients with Breast Cancer Can Improve Diagnosis of Leptomeningeal Metastases.
CLIN CANCER RES. 2021; 27(10): 2798-2806. Doi: 10.1158/1078-0432.CCR-20-3954
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Benton, S; Zhao, JF; Zhang, B; Bahrami, A; Barnhill, RL; Busam, K; Cerroni, L; Cook, MG; de la FouchardiUre, A; Elder, DE; Johansson, I; Landman, G; Lazar, A; LeBoit, P; Lowe, L; Massi, D; Duncan, LM; Messina, J; Mihic-Probst, D; Mihm, MC; Piepkorn, MW; Schmidt, B; Scolyer, RA; Shea, CR; Tetzlaff, MT; Tron, VA; Xu, XW; Yeh, IW; Yun, SJ; Zembowicz, A; Gerami, P Impact of Next-generation Sequencing on Interobserver Agreement and Diagnosis of Spitzoid Neoplasms
AM J SURG PATHOL. 2021; 45(12): 1597-1605. Doi: 10.1097/PAS.0000000000001753
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Berger, M; Thueringer, A; Franz, D; Dandachi, N; Talakić, E; Richtig, G; Richtig, E; Rohrer, PM; Koch, L; Wolf, IH; Koch, C; Rainer, BM; Koeller, M; Pichler, M; Gerritsmann, H; Kashofer, K; Aigelsreiter, A Circulating Tumor DNA as a Marker for Treatment Response in Metastatic Melanoma Patients Using Next-Generation Sequencing-A Prospective Feasibility Study.
Cancers (Basel). 2021; 13(12): Doi: 10.3390/cancers13123101 [OPEN ACCESS]
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Brčić, I; Godschachner, TM; Bergovec, M; Igrec, J; Till, H; Lackner, H; Scheipl, S; Kashofer, K; Brodowicz, T; Leithner, A; Szkandera, J; Liegl-Atzwanger, B Broadening the spectrum of NTRK rearranged mesenchymal tumors and usefulness of pan-TRK immunohistochemistry for identification of NTRK fusions.
Mod Pathol. 2021; 34(2):396-407 Doi: 10.1038/s41379-020-00657-x [OPEN ACCESS]
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Chen, SC; Halliday, CL; Hoenigl, M; Cornely, OA; Meyer, W Scedosporium and Lomentospora Infections: Contemporary Microbiological Tools for the Diagnosis of Invasive Disease.
J Fungi (Basel). 2021; 7(1): Doi: 10.3390/jof7010023 [OPEN ACCESS]
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Scheipl, S; Brcic, I; Moser, T; Fischerauer, S; Riedl, J; Bergovec, M; Smolle, M; Posch, F; Gerger, A; Pichler, M; Stoeger, H; Leithner, A; Heitzer, E; Liegl-Atzwanger, B; Szkandera, J Molecular profiling of soft-tissue sarcomas with FoundationOne® Heme identifies potential targets for sarcoma therapy: a single-centre experience.
Ther Adv Med Oncol. 2021; 13:17588359211029125 Doi: 10.1177/17588359211029125 [OPEN ACCESS]
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Toferer, A; Truschnegg, A; Kashofer, K; Beham-Schmid, C; Beham, A First presentation of a frameshift mutation in the SETD2 gene of a juvenile psammomatoid ossifying fibroma (JPOF) associated with an aneurysmal bone cyst.
DIAGN PATHOL. 2021; 16(1): 91 Doi: 10.1186/s13000-021-01160-w (- Case Report) [OPEN ACCESS]
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Unseld, M; Belic, J; Pierer, K; Zhou, Q; Moser, T; Bauer, R; Piringer, G; Gerger, A; Siebenhüner, A; Speicher, M; Heitzer, E; Prager, GW A higher ctDNA fraction decreases survival in regorafenib-treated metastatic colorectal cancer patients. Results from the regorafenib's liquid biopsy translational biomarker phase II pilot study.
Int J Cancer. 2021; 148(6):1452-1461 Doi: 10.1002/ijc.33303 [OPEN ACCESS]
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Wagner, GE; Totaro, MG; Volland, A; Lipp, M; Saiger, S; Lichtenegger, S; Forstner, P; von, Laer, D; Oberdorfer, G; Steinmetz, I A Novel High-Throughput Nanopore-Sequencing-Based Strategy for Rapid and Automated S-Protein Typing of SARS-CoV-2 Variants.
Viruses. 2021; 13(12): Doi: 10.3390/v13122548 [OPEN ACCESS]
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Zacharias, M; Absenger, G; Kashofer, K; Wurm, R; Lindenmann, J; Terbuch, A; Konjic, S; Sauer, S; Gollowitsch, F; Gorkiewicz, G; Brcic, L Reflex testing in non-small cell lung carcinoma using DNA-and RNA-based next-generation sequencing-a single-center experience
TRANSL LUNG CANCER R. 2021; Doi: 10.21037/tlcr-21-570 [OPEN ACCESS]
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2020

Bedin, M; Boyer, O; Servais, A; Li, Y; Villoing-Gaudé, L; Tête, MJ; Cambier, A; Hogan, J; Baudouin, V; Krid, S; Bensman, A; Lammens, F; Louillet, F; Ranchin, B; Vigneau, C; Bouteau, I; Isnard-Bagnis, C; Mache, CJ; Schäfer, T; Pape, L; Gödel, M; Huber, TB; Benz, M; Klaus, G; Hansen, M; Latta, K; Gribouval, O; Morinière, V; Tournant, C; Grohmann, M; Kuhn, E; Wagner, T; Bole-Feysot, C; Jabot-Hanin, F; Nitschké, P; Ahluwalia, TS; Köttgen, A; Andersen, CBF; Bergmann, C; Antignac, C; Simons, M Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function.
J Clin Invest. 2020; 130(1):335-344 Doi: 10.1172/JCI129937 [OPEN ACCESS]
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Berulava, T; Buchholz, E; Elerdashvili, V; Pena, T; Islam, MR; Lbik, D; Mohamed, BA; Renner, A; von, Lewinski, D; Sacherer, M; Bohnsack, KE; Bohnsack, MT; Jain, G; Capece, V; Cleve, N; Burkhardt, S; Hasenfuss, G; Fischer, A; Toischer, K Changes in m6A RNA methylation contribute to heart failure progression by modulating translation.
Eur J Heart Fail. 2020; 22(1):54-66 Doi: 10.1002/ejhf.1672 [OPEN ACCESS]
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Biasin, V; Crnkovic, S; Sahu-Osen, A; Birnhuber, A; El Agha, E; Sinn, K; Klepetko, W; Olschewski, A; Bellusci, S; Marsh, LM; Kwapiszewska, G PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis.
Am J Physiol Lung Cell Mol Physiol. 2020; 318(4):L684-L697 Doi: 10.1152/ajplung.00128.2019 [OPEN ACCESS]
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Brčić, I; Yamani, F; Inwards, CY; Sumathi, V; Dodd, L; Kreiger, PA; Sittampalam, K; Allred, TR; Kashofer, K; Liegl-Atzwanger, B; Kerr, DA; Nielsen, GP; Rosenberg, AE Giant Cell Tumor of Bone With Cartilage Matrix: A Clinicopathologic Study of 17 Cases.
Am J Surg Pathol. 2020; 44(6): 748-756. Doi: 10.1097/PAS.0000000000001446 [OPEN ACCESS]
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Hinteregger, B; Loeffler, T; Flunkert, S; Neddens, J; Birner-Gruenberger, R; Bayer, TA; Madl, T; Hutter-Paier, B Transgene integration causes RARB downregulation in homozygous Tg4-42 mice.
Sci Rep. 2020; 10(1): 6377-6377. Doi: 10.1038/s41598-020-63512-8 [OPEN ACCESS]
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Igrec, J; Brčić, I; Igrec, R; Bergovec, M; Kashofer, K; Fuchsjäger, M; Leithner, A; Liegl-Atzwanger, B Intraarticular Nodular Fasciitis of the Knee With MHY9-USP6 Fusion: A Case Report.
Int J Surg Pathol. 2020; 28(6):672-677 Doi: 10.1177/1066896920908054 (- Case Report)
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Kiss, A; Heber, S; Kramer, AM; Hackl, M; Skalicky, S; Hallström, S; Podesser, BK; Santer, D MicroRNA Expression Profile Changes after Cardiopulmonary Bypass and Ischemia/Reperfusion-Injury in a Porcine Model of Cardioplegic Arrest.
Diagnostics (Basel). 2020; 10(4): Doi: 10.3390/diagnostics10040240 [OPEN ACCESS]
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Lampignano, R; Neumann, MHD; Weber, S; Kloten, V; Herdean, A; Voss, T; Groelz, D; Babayan, A; Tibbesma, M; Schlumpberger, M; Chemi, F; Rothwell, DG; Wikman, H; Galizzi, J-P; Bergheim, IR; Russnes, H; Mussolin, B; Bonin, S; Voight, C; Musa, H; Pinzani, P; Lianidou, E; Brady, G; Speicher, MR; Pantel, K; Betsou, F, Schuuring, E; Kubista, M; Ammerlaan, W; Sprenger-Haussels, M; Schlange, T; Heitzer, E Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows
The Open Clinical Chemistry Journal. 2020; 66(1): 149-160. Doi: 10.1373/clinchem.2019.306837 [OPEN ACCESS]
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Perakis, SO; Weber, S; Zhou, Q; Graf, R; Hojas, S; Riedl, JM; Gerger, A; Dandachi, N; Balic, M; Hoefler, G; Schuuring, E; Groen, HJM; Geigl, JB; Heitzer, E; Speicher, MR Comparison of three commercial decision support platforms for matching of next-generation sequencing results with therapies in patients with cancer.
ESMO Open. 2020; 5(5):e000872 Doi: 10.1136/esmoopen-2020-000872 [OPEN ACCESS]
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Skálová, A; Banečkova, M; Thompson, LDR; Ptáková, N; Stevens, TM; Brcic, L; Hyrcza, M; Michal, M; Simpson, RHW; Santana, T; Michal, M; Vaněček, T; Leivo, I Expanding the Molecular Spectrum of Secretory Carcinoma of Salivary Glands With a Novel VIM-RET Fusion.
Am J Surg Pathol. 2020; 44(10):1295-1307 Doi: 10.1097/PAS.0000000000001535
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Sunitsch, S; Reisinger, J; Abete, L; Kashofer, K; Regitnig, P Metaplastic papillary tumour of the fallopian tube, a rare entity, analysed by next-generation sequencing.
Histopathology. 2020; 76(6):923-924 Doi: 10.1111/his.14043 [OPEN ACCESS]
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Thannesberger, J; Rascovan, N; Eisenmann, A; Klymiuk, I; Zittra, C; Fuehrer, HP; Scantlebury-Manning, T; Gittens-St Hilaire, M; Austin, S; Landis, RC; Steininger, C Highly Sensitive Virome Characterization of Aedes aegypti and Culex pipiens Complex from Central Europe and the Caribbean Reveals Potential for Interspecies Viral Transmission.
Pathogens. 2020; 9(9): Doi: 10.3390/pathogens9090686 [OPEN ACCESS]
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2019

Dinter, H; Bohnenberger, H; Beck, J; Bornemann-Kolatzki, K; Schütz, E; Küffer, S; Klein, L; Franks, TJ; Roden, A; Emmert, A; Hinterthaner, M; Marino, M; Brcic, L; Popper, H; Weis, CA; Pelosi, G; Marx, A; Ströbel, P Molecular Classification of Neuroendocrine Tumors of the Thymus.
J Thorac Oncol. 2019; 14(8):1472-1483 Doi: 10.1016/j.jtho.2019.04.015 [OPEN ACCESS]
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Gallon, R; Mühlegger, B; Wenzel, SS; Sheth, H; Hayes, C; Aretz, S; Dahan, K; Foulkes, W; Kratz, CP; Ripperger, T; Azizi, AA; Baris Feldman, H; Chong, AL; Demirsoy, U; Florkin, B; Imschweiler, T; Januszkiewicz-Lewandowska, D; Lobitz, S; Nathrath, M; Pander, HJ; Perez-Alonso, V; Perne, C; Ragab, I; Rosenbaum, T; Rueda, D; Seidel, MG; Suerink, M; Taeubner, J; Zimmermann, SY; Zschocke, J; Borthwick, GM; Burn, J; Jackson, MS; Santibanez-Koref, M; Wimmer, K A sensitive and scalable microsatellite instability assay to diagnose constitutional mismatch repair deficiency by sequencing of peripheral blood leukocytes.
Hum Mutat. 2019; 40(5):649-655 Doi: 10.1002/humu.23721 [OPEN ACCESS]
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Heitzer, E; Groenewoud, A; Meditz, K; Lohberger, B; Liegl-Atzwanger, B; Prokesch, A; Kashofer, K; Behrens, D; Haybaeck, J; Kolb-Lenz, D; Koefeler, H; Riedl, S; Schaider, H; Fischer, C; Snaar-Jagalska, BE; de'Jong, D; Szuhai, K; Zweytick, D; Rinner, B Human melanoma brain metastases cell line MUG-Mel1, isolated clones and their detailed characterization.
Sci Rep. 2019; 9(1):4096-4096 Doi: 10.1038/s41598-019-40570-1 [OPEN ACCESS]
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IJspeert, H; van Schouwenburg, PA; Pico-Knijnenburg, I; Loeffen, J; Brugieres, L; Driessen, GJ; Blattmann, C; Suerink, M; Januszkiewicz-Lewandowska, D; Azizi, AA; Seidel, MG; Jacobs, H; van der Burg, M Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans.
Front Immunol. 2019; 10: 1913-1913. Doi: 10.3389/fimmu.2019.01913 [OPEN ACCESS]
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Kispal, ZF; Vajda, P; Kardos, D; Klymiuk, I; Moissl-Eichinger, C; Castellani, C; Singer, G; Till, H The local microbiome after pediatric bladder augmentation: intestinal segments and the native urinary bladder host similar mucosal microbiota.
J Pediatr Urol. 2019; 15(1):30.e1-30.30 Doi: 10.1016/j.jpurol.2018.07.028 [OPEN ACCESS]
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Pichler, R; Compérat, E; Klatte, T; Pichler, M; Loidl, W; Lusuardi, L; Schmidinger, M Renal Cell Carcinoma with Sarcomatoid Features: Finally New Therapeutic Hope?
Cancers (Basel). 2019; 11(3): 422 Doi: 10.3390/cancers11030422 [OPEN ACCESS]
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Prochazka, KT; Pregartner, G; Rücker, FG; Heitzer, E; Pabst, G; Wölfler, A; Zebisch, A; Berghold, A; Döhner, K; Sill, H Clinical implications of subclonal TP53 mutations in acute myeloid leukemia.
Haematologica. 2019; 104(3):516-523 Doi: 10.3324/haematol.2018.205013 [OPEN ACCESS]
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Saggini, A; Cerroni, L; Casini, B; Baciorri, F; Cota, C Primary intrafascial desmoplastic melanoma with pseudoglandular differentiation and aberrant cytokeratins expression: An exceptional presentation.
Pathol Res Pract. 2019; 215(12):152668-152668 Doi: 10.1016/j.prp.2019.152668 (- Case Report)
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Seeboeck, R; Sarne, V; Haybaeck, J Current Coverage of the mTOR Pathway by Next-Generation Sequencing Oncology Panels.
Int J Mol Sci. 2019; 20(3): Doi: 10.3390/ijms20030690 [OPEN ACCESS]
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Spasic, S; Brcic, I; Freire, R; Garcia-Buitrago, MT; Rosenberg, AE Epithelioid Hemangioendothelioma of the Bowel in Crohn's Disease: The First Reported Case.
Int J Surg Pathol. 2019; 27(4): 423-426. Doi: 10.1177/1066896918801527
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Till, H; Kashofer, K; Laje, P; ElHaddad, A; Warncke, G; Gorkiewicz, G; Singer, G Microbial Evidence in Congenital Pulmonary Airway Malformations of Young Asymptomatic Infants.
J Laparoendosc Adv Surg Tech A. 2019; Doi: 10.1089/lap.2017.0456
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Tripolszki, K; Gampawar, P; Schmidt, H; Nagy, ZF; Nagy, D; Klivényi, P; Engelhardt, JI; Széll, M Comprehensive Genetic Analysis of a Hungarian Amyotrophic Lateral Sclerosis Cohort.
Front Genet. 2019; 10: 732-732. Doi: 10.3389/fgene.2019.00732 [OPEN ACCESS]
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