Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: MOUSE, . Treffer: 798

2023

Foßelteder, J; Pabst, G; Sconocchia, T; Schlacher, A; Auinger, L; Kashofer, K; Beham-Schmid, C; Trajanoski, S; Waskow, C; Schöll, W; Sill, H; Zebisch, A; Wölfler, A; Thomas, D; Reinisch, A Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.
Leukemia. 2023; Doi: 10.1038/s41375-023-01848-6
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Liebscher, G; Vujic, N; Schreiber, R; Heine, M; Krebiehl, C; Duta-Mare, M; Lamberti, G; de, Smet, CH; Hess, MW; Eichmann, TO; Hölzl, S; Scheja, L; Heeren, J; Kratky, D; Huber, LA The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
Mol Metab. 2023; 101705 Doi: 10.1016/j.molmet.2023.101705
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Messerer, J; Wrede, C; Schipke, J; Brandenberger, C; Abdellatif, M; Eisenberg, T; Madeo, F; Sedej, S; Mühlfeld, C Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice.
J Anat. 2023; 242(1):91-101 Doi: 10.1111/joa.13618 [OPEN ACCESS]
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Sarsembayeva, A; Kienzl, M; Gruden, E; Ristic, D; Maitz, K; Valadez-Cosmes, P; Santiso, A; Hasenoehrl, C; Brcic, L; Lindenmann, J; Kargl, J; Schicho, R Cannabinoid receptor 2 plays a pro-tumorigenic role in non-small cell lung cancer by limiting anti-tumor activity of CD8+ T and NK cells.
Front Immunol. 2022; 13:997115 Doi: 10.3389/fimmu.2022.997115 [OPEN ACCESS]
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2022

Abdellatif, M; Madeo, F; Kroemer, G; Sedej, S Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Autophagy. 2022; 18(10):2500-2502 Doi: 10.1080/15548627.2022.2095835 [OPEN ACCESS]
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Abdellatif, M; Trummer-Herbst, V; Heberle, AM; Humnig, A; Pendl, T; Durand, S; Cerrato, G; Hofer, SJ; Islam, M; Voglhuber, J; Ramos, Pittol, JM; Kepp, O; Hoefler, G; Schmidt, A; Rainer, PP; Scherr, D; von, Lewinski, D; Bisping, E; McMullen, JR; Diwan, A; Eisenberg, T; Madeo, F; Thedieck, K; Kroemer, G; Sedej, S Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Circulation. 2022; 145(25):1853-1866 Doi: 10.1161/CIRCULATIONAHA.122.059863 [OPEN ACCESS]
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Birnhuber, A; Jandl, K; Biasin, V; Fließer, E; Valzano, F; Marsh, LM; Krolczik, C; Olschewski, A; Wilhelm, J; Toller, W; Heinemann, A; Olschewski, H; Wygrecka, M; Kwapiszewska, G Pirfenidone exacerbates Th2-driven vasculopathy in a mouse model of systemic sclerosis-associated interstitial lung disease.
Eur Respir J. 2022; 60(4): Doi: 10.1183/13993003.02347-2021 [OPEN ACCESS]
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Bresilla, D; Habisch, H; Pritišanac, I; Zarse, K; Parichatikanond, W; Ristow, M; Madl, T; Madreiter-Sokolowski, CT The sex-specific metabolic signature of C57BL/6NRj mice during aging.
Sci Rep. 2022; 12(1):21050 Doi: 10.1038/s41598-022-25396-8 [OPEN ACCESS]
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Chao, X; Wang, S; Fulte, S; Ma, X; Ahamed, F; Cui, W; Liu, Z; Rülicke, T; Zatloukal, K; Zong, WX; Liu, W; Ni, HM; Ding, WX Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy.
J Hepatol. 2022; 76(3):639-651 Doi: 10.1016/j.jhep.2021.10.014 [OPEN ACCESS]
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Eisner, H; Riegler-Berket, L; Gamez, CFR; Sagmeister, T; Chalhoub, G; Darnhofer, B; Jazleena, PJ; Birner-Gruenberger, R; Pavkov-Keller, T; Haemmerle, G; Schoiswohl, G; Oberer, M The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1.
Int J Mol Sci. 2022; 23(21): Doi: 10.3390/ijms232113101 [OPEN ACCESS]
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Goeritzer, M; Schlager, S; Kuentzel, KB; Vujić, N; Korbelius, M; Rainer, S; Kolb, D; Mussbacher, M; Salzmann, M; Schrottmaier, WC; Assinger, A; Schlagenhauf, A; Madreiter-Sokolowski, CT; Blass, S; Eichmann, TO; Graier, WF; Kratky, D Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo.
Cells. 2022; 11(5): Doi: 10.3390/cells11050850 [OPEN ACCESS]
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Heidegger, I; Fotakis, G; Offermann, A; Goveia, J; Daum, S; Salcher, S; Noureen, A; Timmer-Bosscha, H; Schäfer, G; Walenkamp, A; Perner, S; Beatovic, A; Moisse, M; Plattner, C; Krogsdam, A; Haybaeck, J; Sopper, S; Thaler, S; Keller, MA; Klocker, H; Trajanoski, Z; Wolf, D; Pircher, A Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer.
Mol Cancer. 2022; 21(1): 132 Doi: 10.1186/s12943-022-01597-7 [OPEN ACCESS]
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Hochgerner, M; Sturm, EM; Schnoegl, D; Kwapiszewska, G; Olschewski, H; Marsh, LM Low oxygen levels decrease adaptive immune responses and ameliorate experimental asthma in mice.
Allergy. 2022; 77(3):870-882 Doi: 10.1111/all.15020 [OPEN ACCESS]
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Jandl, K; Marsh, LM; Mutgan, AC; Crnkovic, S; Valzano, F; Zabini, D; Hoffmann, J; Foris, V; Gschwandtner, E; Klepetko, W; Prosch, H; Flick, H; Brcic, L; Kern, I; Heinemann, A; Olschewski, H; Kovacs, G; Kwapiszewska, G Impairment of the NKT-STAT1-CXCL9 Axis Contributes to Vessel Fibrosis in Pulmonary Hypertension Caused by Lung Fibrosis.
Am J Respir Crit Care Med. 2022; 206(8):981-998 Doi: 10.1164/rccm.202201-0142OC
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Joshi, L; Plastira, I; Bernhart, E; Reicher, H; Koshenov, Z; Graier, WF; Vujic, N; Kratky, D; Rivera, R; Chun, J; Sattler, W Lysophosphatidic Acid Receptor 5 (LPA5) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro.
Cells. 2022; 11(7): Doi: 10.3390/cells11071071 [OPEN ACCESS]
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Karacay, C; Prietl, B; Harer, C; Ehall, B; Haudum, CW; Bounab, K; Franz, J; Eisenberg, T; Madeo, F; Kolb, D; Hingerl, K; Hausl, M; Magnes, C; Mautner, SI; Kotzbeck, P; Pieber, TR The effect of spermidine on autoimmunity and beta cell function in NOD mice.
Sci Rep. 2022; 12(1):4502 Doi: 10.1038/s41598-022-08168-2 [OPEN ACCESS]
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Klec, C; Knutsen, E; Schwarzenbacher, D; Jonas, K; Pasculli, B; Heitzer, E; Rinner, B; Krajina, K; Prinz, F; Gottschalk, B; Ulz, P; Deutsch, A; Prokesch, A; Jahn, SW; Lellahi, SM; Perander, M; Barbano, R; Graier, WF; Parrella, P; Calin, GA; Pichler, M ALYREF, a novel factor involved in breast carcinogenesis, acts through transcriptional and post-transcriptional mechanisms selectively regulating the short NEAT1 isoform.
Cell Mol Life Sci. 2022; 79(7): 391 Doi: 10.1007/s00018-022-04402-2 [OPEN ACCESS]
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Krstic, J; Reinisch, I; Schindlmaier, K; Galhuber, M; Riahi, Z; Berger, N; Kupper, N; Moyschewitz, E; Auer, M; Michenthaler, H; Nössing, C; Depaoli, MR; Ramadani-Muja, J; Usluer, S; Stryeck, S; Pichler, M; Rinner, B; Deutsch, AJA; Reinisch, A; Madl, T; Chiozzi, RZ; Heck, AJR; Huch, M; Malli, R; Prokesch, A Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism.
Sci Adv. 2022; 8(3):eabh2635 Doi: 10.1126/sciadv.abh2635 [OPEN ACCESS]
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Kuentzel, KB; Bradić, I; Mihalič, ZN; Korbelius, M; Rainer, S; Pirchheim, A; Kargl, J; Kratky, D Dysregulation of Placental Lipid Hydrolysis by High-Fat/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice.
Int J Mol Sci. 2022; 23(20): 12286 Doi: 10.3390/ijms232012286 [OPEN ACCESS]
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Li, H; Perino, A; Huang, Q; Von, Alvensleben, GVG; Banaei-Esfahani, A; Velazquez-Villegas, LA; Gariani, K; Korbelius, M; Bou, Sleiman, M; Imbach, J; Sun, Y; Li, X; Bachmann, A; Goeminne, LJE; Gallart-Ayala, H; Williams, EG; Ivanisevic, J; Auwerx, J; Schoonjans, K Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis.
Cell Metab. 2022; 34(10): 1594-1610.e4. Doi: 10.1016/j.cmet.2022.08.015 [OPEN ACCESS]
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Mooslechner, AA; Schuller, M; Artinger, K; Kirsch, AH; Schabhüttl, C; Eller, P; Rosenkranz, AR; Eller, K Low-Dose rIL-15 Protects from Nephrotoxic Serum Nephritis via CD8+ T Cells.
Cells. 2022; 11(22): Doi: 10.3390/cells11223656 [OPEN ACCESS]
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Oster, M; Galhuber, M; Krstic, J; Steinhoff, JS; Lenihan-Geels, G; Wulff, S; Kiefer, MF; Petricek, KM; Wowro, SJ; Flores, RE; Yang, N; Li, C; Meng, Y; Reinisch, I; Sommerfeld, M; Weger, S; Habisch, H; Madl, T; Schulz, TJ; Prokesch, A; Schupp, M Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis.
J Biol Chem. 2022; 298(9):102287 Doi: 10.1016/j.jbc.2022.102287 [OPEN ACCESS]
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Pusch, LM; Riegler-Berket, L; Oberer, M; Zimmermann, R; Taschler, U α/β-Hydrolase Domain-Containing 6 (ABHD6)- A Multifunctional Lipid Hydrolase.
Metabolites. 2022; 12(8): Doi: 10.3390/metabo12080761 [OPEN ACCESS]
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Reiser, E; Bazzano, MV; Solano, ME; Haybaeck, J; Schatz, C; Mangesius, J; Ganswindt, U; Toth, B Unlaid Eggs: Ovarian Damage after Low-Dose Radiation.
Cells. 2022; 11(7): Doi: 10.3390/cells11071219 [OPEN ACCESS]
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Riegler-Berket, L; Wechselberger, L; Cerk, IK; Padmanabha, Das, KM; Viertlmayr, R; Kulminskaya, N; Rodriguez, Gamez, CF; Schweiger, M; Zechner, R; Zimmermann, R; Oberer, M Residues of the minimal sequence of G0S2 collectively contribute to ATGL inhibition while C-and N-terminal extensions promote binding to ATGL.
Biochim Biophys Acta Mol Cell Biol Lipids. 2022; 1867(3): 159105 Doi: 10.1016/j.bbalip.2021.159105
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Texler, B; Zollner, A; Reinstadler, V; Reider, SJ; Macheiner, S; Jelusic, B; Pfister, A; Watschinger, C; Przysiecki, N; Tilg, H; Oberacher, H; Moschen, AR Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics.
Cell Mol Gastroenterol Hepatol. 2021; 13(2):383-404 Doi: 10.1016/j.jcmgh.2021.09.004 [OPEN ACCESS]
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Werder, RB; Ullah, MA; Rahman, MM; Simpson, J; Lynch, JP; Collinson, N; Rittchen, S; Rashid, RB; Sikder, MAA; Handoko, HY; Curren, BF; Sebina, I; Hartel, G; Bissell, A; Ngo, S; Yarlagadda, T; Hasnain, SZ; Lu, W; Sohal, SS; Martin, M; Bowler, S; Burr, LD; Martinez, LO; Robaye, B; Spann, K; Ferreira, MAR; Phipps, S Targeting the P2Y13 Receptor Suppresses IL-33 and HMGB1 Release and Ameliorates Experimental Asthma.
Am J Respir Crit Care Med. 2022; 205(3):300-312 Doi: 10.1164/rccm.202009-3686OC
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2021

Alesutan, I; Luong, TTD; Schelski, N; Masyout, J; Hille, S; Schneider, MP; Graham, D; Zickler, D; Verheyen, N; Estepa, M; Pasch, A; Maerz, W; Tomaschitz, A; Pilz, S; Frey, N; Lang, F; Delles, C; Müller, OJ; Pieske, B; Eckardt, KU; Scherberich, J; Voelkl, J Circulating uromodulin inhibits vascular calcification by interfering with pro-inflammatory cytokine signalling.
Cardiovasc Res. 2021; 117(3):930-941 Doi: 10.1093/cvr/cvaa081
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Alonso, N; Wani, S; Rose, L; Van't, Hof, RJ; Ralston, SH; Albagha, OME Insertion Mutation in Tnfrsf11a Causes a Paget's Disease-Like Phenotype in Heterozygous Mice and Osteopetrosis in Homozygous Mice.
J Bone Miner Res. 2021; 36(7):1376-1386 Doi: 10.1002/jbmr.4288
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Álvarez, RM; García, AB; Riesco-Fagundo, C; Martín, JI; Varela, C; Rodríguez, Hergueta, A; González, Cantalapiedra, E; Oyarzabal, J; Di, Geronimo, B; Lorenzo, M; Albarrán, MI; Cebriá, A; Cebrián, D; Martínez-González, S; Blanco-Aparicio, C; Pastor, J Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors.
Eur J Med Chem. 2021; 211: 113109 Doi: 10.1016/j.ejmech.2020.113109
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Ashok, A; Chaudhary, S; Wise, AS; Rana, NA; McDonald, D; Kritikos, AE; Lindner, E; Singh, N Release of Iron-Loaded Ferritin in Sodium Iodate-Induced Model of Age Related Macular Degeneration: An In-Vitro and In-Vivo Study.
ANTIOXIDANTS-BASEL. 2021; 10(8): 1253 Doi: 10.3390/antiox10081253 [OPEN ACCESS]
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Berg, JL; Perfler, B; Hatzl, S; Mayer, MC; Wurm, S; Uhl, B; Reinisch, A; Klymiuk, I; Tierling, S; Pregartner, G; Bachmaier, G; Berghold, A; Geissler, K; Pichler, M; Hoefler, G; Strobl, H; Wölfler, A; Sill, H; Zebisch, A Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia.
Clin Epigenetics. 2021; 13(1): 1-1. Doi: 10.1186/s13148-020-00979-2 [OPEN ACCESS]
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Chaudhary, S; Ashok, A; Wise, AS; Rana, NA; Kritikos, AE; Lindner, E; Singh, N β-Cleavage of the prion protein in the human eye: Implications for the spread of infectious prions and human ocular disorders.
EXP EYE RES. 2021; 212: 108787 Doi: 10.1016/j.exer.2021.108787 [OPEN ACCESS]
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Fengler, VH; Macheiner, T; Goessler, W; Ratzer, M; Haybaeck, J; Sargsyan, K Hepatic Response of Magnesium-Restricted Wild Type Mice.
Metabolites. 2021; 11(11): Doi: 10.3390/metabo11110762 [OPEN ACCESS]
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Galhuber, M; Kupper, N; Dohr, G; Gauster, M; Kwapiszewska, G; Olschewski, A; Jandl, K; Gschwandtner, E; Schweiger, M; Kratky, D; Leitinger, G; Prokesch, A; Kolb, D Simple method of thawing cryo-stored samples preserves ultrastructural features in electron microscopy.
Histochem Cell Biol. 2021; 155(5):593-603 Doi: 10.1007/s00418-020-01952-z [OPEN ACCESS]
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Gissler, MC; Scherrer, P; Anto-Michel, N; Pennig, J; Hoppe, N; Füner, L; Härdtner, C; Stachon, P; Li, X; Mitre, LS; Marchini, T; Madl, J; Wadle, C; Hilgendorf, I; von, Zur, Mühlen, C; Bode, C; Weber, C; Lutgens, E; Wolf, D; Gerdes, N; Zirlik, A; Willecke, F Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice.
Thromb Haemost. 2021; 121(11):1530-1540 Doi: 10.1055/a-1397-1858
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Helmstadter, KG; Ljubojevic-Holzer, S; Wood, BM; Taheri, KD; Sedej, S; Erickson, JR; Bossuyt, J; Bers, DM CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes.
Basic Res Cardiol. 2021; 116(1):11-11 Doi: 10.1007/s00395-021-00850-2 [OPEN ACCESS]
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Hinteregger, B; Loeffler, T; Flunkert, S; Neddens, J; Bayer, TA; Madl, T; Hutter-Paier, B Metabolic, Phenotypic, and Neuropathological Characterization of the Tg4-42 Mouse Model for Alzheimer's Disease.
J ALZHEIMERS DIS. 2021; 80(3): 1151-1168. Doi: 10.3233/JAD-201204 [OPEN ACCESS]
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Hisada, Y; Garratt, KB; Maqsood, A; Grover, SP; Kawano, T; Cooley, BC; Erlich, J; Moik, F; Flick, MJ; Pabinger, I; Mackman, N; Ay, C Plasminogen activator inhibitor 1 and venous thrombosis in pancreatic cancer.
Blood Adv. 2021; 5(2):487-495 Doi: 10.1182/bloodadvances.2020003149 [OPEN ACCESS]
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Holzmann, C; Witt, M; Rolfs, A; Antipova, V; Wree, A Gender-Specific Effects of Two Treatment Strategies in a Mouse Model of Niemann-Pick Disease Type C1
INT J MOL SCI. 2021; 22(5): 2539 Doi: 10.3390/ijms22052539 [OPEN ACCESS]
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Kienzl, M; Hasenoehrl, C; Maitz, K; Sarsembayeva, A; Taschler, U; Valadez-Cosmes, P; Kindler, O; Ristic, D; Raftopoulou, S; Santiso, A; Bärnthaler, T; Brcic, L; Hahnefeld, L; Gurke, R; Thomas, D; Geisslinger, G; Kargl, J; Schicho, R Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer.
Oncoimmunology. 2021; 10(1): 1965319 Doi: 10.1080/2162402X.2021.1965319 [OPEN ACCESS]
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Klymiuk, I; Singer, G; Castellani, C; Trajanoski, S; Obermüller, B; Till, H Characterization of the Luminal and Mucosa-Associated Microbiome along the Gastrointestinal Tract: Results from Surgically Treated Preterm Infants and a Murine Model.
Nutrients. 2021; 13(3): Doi: 10.3390/nu13031030 [OPEN ACCESS]
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Knuplez, E; Kienzl, M; Trakaki, A; Schicho, R; Heinemann, A; Sturm, EM; Marsche, G The anti-parasitic drug miltefosine suppresses human eosinophil activation and ameliorates murine allergic inflammation in vivo.
Br J Pharmacol. 2021; 178(5):1234-1248 Doi: 10.1111/bph.15368 [OPEN ACCESS]
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Kovács, D; Vántus, VB; Vámos, E; Kálmán, N; Schicho, R; Gallyas, F; Radnai, B Olaparib: A Clinically Applied PARP Inhibitor Protects from Experimental Crohn's Disease and Maintains Barrier Integrity by Improving Bioenergetics through Rescuing Glycolysis in Colonic Epithelial Cells.
Oxid Med Cell Longev. 2021; 2021: 7308897 Doi: 10.1155/2021/7308897 [OPEN ACCESS]
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Kuentzel, KB; Bradić, I; Akhmetshina, A; Korbelius, M; Rainer, S; Kolb, D; Gauster, M; Vujić, N; Kratky, D Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth.
Int J Mol Sci. 2021; 22(19): Doi: 10.3390/ijms221910416 [OPEN ACCESS]
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Leb-Reichl, VM; Kienzl, M; Kaufmann, A; Stoecklinger, A; Tockner, B; Kitzmueller, S; Zaborsky, N; Steiner, M; Brachtl, G; Trattner, L; Kreideweiss, P; Reinsch, C; Panzner, S; Greil, R; Strunk, D; Bauer, JW; Gratz, IK; Guttmann-Gruber, C; Piñón, Hofbauer, J Leveraging immune memory against measles virus as an antitumor strategy in a preclinical model of aggressive squamous cell carcinoma.
J Immunother Cancer. 2021; 9(10): Doi: 10.1136/jitc-2020-002170 [OPEN ACCESS]
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Leipner, J; Dederichs, TS; von, Ehr, A; Rauterberg, S; Ehlert, C; Merz, J; Dufner, B; Hoppe, N; Krebs, K; Heidt, T; von, Zur, Muehlen, C; Stachon, P; Ley, K; Wolf, D; Zirlik, A; Bode, C; Hilgendorf, I; Härdtner, C Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe-/- mice.
Mol Metab. 2021; 53:101250 Doi: 10.1016/j.molmet.2021.101250 [OPEN ACCESS]
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Luschnig, P; Kienzl, M; Roula, D; Pilic, J; Atallah, R; Heinemann, A; Sturm, EM The JAK1/2 inhibitor baricitinib suppresses eosinophil effector function and restricts allergen-induced airway eosinophilia.
Biochem Pharmacol. 2021; 192: 114690 Doi: 10.1016/j.bcp.2021.114690
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Manning, EP; Ramachandra, AB; Schupp, JC; Cavinato, C; Raredon, MSB; Bärnthaler, T; Cosme, C; Singh, I; Tellides, G; Kaminski, N; Humphrey, JD Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data.
Front Physiol. 2021; 12:726253 Doi: 10.3389/fphys.2021.726253 [OPEN ACCESS]
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Najumudeen, AK; Ceteci, F; Fey, SK; Hamm, G; Steven, RT; Hall, H; Nikula, CJ; Dexter, A; Murta, T; Race, AM; Sumpton, D; Vlahov, N; Gay, DM; Knight, JRP; Jackstadt, R; Leach, JDG; Ridgway, RA; Johnson, ER; Nixon, C; Hedley, A; Gilroy, K; Clark, W; Malla, SB; Dunne, PD; Rodriguez-Blanco, G; Critchlow, SE; Mrowinska, A; Malviya, G; Solovyev, D; Brown, G; Lewis, DY; Mackay, GM; Strathdee, D; Tardito, S; Gottlieb, E; Takats, Z; Barry, ST; Goodwin, RJA; Bunch, J; Bushell, M; Campbell, AD; Sansom, OJ, , CRUK, Rosetta, Grand, Challenge, Consortium The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Nat Genet. 2021; 53(1):16-26 Doi: 10.1038/s41588-020-00753-3
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