Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: METABOLOMICS, . Treffer: 78

2023

Crowther, LM; Poms, M; Zandl-Lang, M; Abela, L; Hartmann, H; Seiler, M; Mathis, D; Plecko, B Metabolomics analysis of antiquitin deficiency in cultured human cells and plasma: Relevance to pyridoxine-dependent epilepsy.
J Inherit Metab Dis. 2023; 46(1): 129-142. Doi: 10.1002/jimd.12569 [OPEN ACCESS]
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Tripolt, NJ; Hofer, SJ; Pferschy, PN; Aziz, F; Durand, S; Aprahamian, F; Nirmalathasan, N; Waltenstorfer, M; Eisenberg, T; Obermayer, AMA; Riedl, R; Kojzar, H; Moser, O; Sourij, C; Bugger, H; Oulhaj, A; Pieber, TR; Zanker, M; Kroemer, G; Madeo, F; Sourij, H Glucose Metabolism and Metabolomic Changes in Response to Prolonged Fasting in Individuals with Obesity, Type 2 Diabetes and Non-Obese People-A Cohort Trial.
Nutrients. 2023; 15(3): Doi: 10.3390/nu15030511 [OPEN ACCESS]
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2022

Agamennone, V; Abuja, PM; Basic, M; De, Angelis, M; Gessner, A; Keijser, B; Larsen, M; Pinart, M; Nimptsch, K; Pujos-Guillot, E; Schlicht, K; Sharon, I; Untersmayr, E; Laudes, M; Pischon, T; Bouwman, J; On, Behalf, Of, The, Consortium HDHL-INTIMIC: A European Knowledge Platform on Food, Diet, Intestinal Microbiomics, and Human Health.
Nutrients. 2022; 14(9): Doi: 10.3390/nu14091881 [OPEN ACCESS]
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Chary, S; Amrein, K; Mahmoud, SH; Lasky-Su, JA; Christopher, KB Sex-Specific Catabolic Metabolism Alterations in the Critically Ill following High Dose Vitamin D.
METABOLITES. 2022; 12(3): Doi: 10.3390/metabo12030207 [OPEN ACCESS]
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Ghini, V; Abuja, PM; Polasek, O; Kozera, L; Laiho, P; Anton, G; Zins, M; Klovins, J; Metspalu, A; Wichmann, HE; Gieger, C; Luchinat, C; Zatloukal, K; Turano, P Impact of the pre-examination phase on multicenter metabolomic studies.
N Biotechnol. 2022; 68:37-47 Doi: 10.1016/j.nbt.2022.01.006
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Haupt, S; Niedrist, T; Sourij, H; Schwarzinger, S; Moser, O The Impact of Exercise on Telomere Length, DNA Methylation and Metabolic Footprints.
Cells. 2022; 11(1): Doi: 10.3390/cells11010153 [OPEN ACCESS]
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Kreuzer, K; Reiter, A; Birkl-Töglhofer, AM; Dalkner, N; Mörkl, S; Mairinger, M; Fleischmann, E; Fellendorf, F; Platzer, M; Lenger, M; Färber, T; Seidl, M; Birner, A; Queissner, R; Mendel, LS; Maget, A; Kohlhammer-Dohr, A; Häussl, A; Wagner-Skacel, J; Schöggl, H; Amberger-Otti, D; Painold, A; Lahousen-Luxenberger, T; Leitner-Afschar, B; Haybaeck, J; Habisch, H; Madl, T; Reininghaus, E; Bengesser, S The PROVIT Study-Effects of Multispecies Probiotic Add-on Treatment on Metabolomics in Major Depressive Disorder-A Randomized, Placebo-Controlled Trial.
Metabolites. 2022; 12(8): Doi: 10.3390/metabo12080770 [OPEN ACCESS]
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Lenard, AJ; Mulder, FAA; Madl, T Solvent paramagnetic relaxation enhancement as a versatile method for studying structure and dynamics of biomolecular systems
PROG NUCL MAG RES SP. 2022; 132: 113-139. Doi: 10.1016/j.pnmrs.2022.09.001
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Reinke, SN; Naz, S; Chaleckis, R; Gallart-Ayala, H; Kolmert, J; Kermani, NZ; Tiotiu, A; Broadhurst, DI; Lundqvist, A; Olsson, H; Ström, M; Wheelock, ÅM; Gómez, C; Ericsson, M; Sousa, AR; Riley, JH; Bates, S; Scholfield, J; Loza, M; Baribaud, F; Bakke, PS; Caruso, M; Chanez, P; Fowler, SJ; Geiser, T; Howarth, P; Horváth, I; Krug, N; Montuschi, P; Behndig, A; Singer, F; Musial, J; Shaw, DE; Dahlén, B; Hu, S; Lasky-Su, J; Sterk, PJ; Chung, KF; Djukanovic, R; Dahlén, SE; Adcock, IM; Wheelock, CE, , U-BIOPRED, Study, Group Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Eur Respir J. 2022; 59(6): Doi: 10.1183/13993003.01733-2021 [OPEN ACCESS]
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Schadler, P; Lohberger, B; Thauerer, B; Faschingbauer, M; Kullich, W; Stradner, MH; Leithner, A; Ritschl, V; Omara, M; Steinecker-Frohnwieser, B The Association of Blood Biomarkers and Body Mass Index in Knee Osteoarthritis: A Cross-Sectional Study.
Cartilage. 2022; 13(1): 19476035211069251 Doi: 10.1177/19476035211069251 [OPEN ACCESS]
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Schuller, M; Oberhuber, M; Prietl, B; Zügner, E; Prugger, EM; Magnes, C; Kirsch, AH; Schmaldienst, S; Pieber, T; Brodmann, M; Rosenkranz, AR; Eller, P; Eller, K Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
Int J Mol Sci. 2022; 23(22): Doi: 10.3390/ijms232214089 [OPEN ACCESS]
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Sigurdsson, MI; Kobayashi, H; Amrein, K; Nakahira, K; Rogers, AJ; Pinilla-Vera, M; Baron, RM; Fredenburgh, LE; Lasky-Su, JA; Christopher, KB Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study.
CRIT CARE. 2022; 26(1): 321 Doi: 10.1186/s13054-022-04174-y [OPEN ACCESS]
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Zandl-Lang, M; Züllig, T; Trötzmüller, M; Naegelin, Y; Abela, L; Wilken, B; Scholl-Buergi, S; Karall, D; Kappos, L; Köfeler, H; Plecko, B Changes in the Cerebrospinal Fluid and Plasma Lipidome in Patients with Rett Syndrome.
Metabolites. 2022; 12(4): 291 Doi: 10.3390/metabo12040291 [OPEN ACCESS]
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Zhou, Q; Kerbl-Knapp, J; Zhang, F; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T Metabolomic Profiles of Mouse Tissues Reveal an Interplay between Aging and Energy Metabolism.
Metabolites. 2021; 12(1): Doi: 10.3390/metabo12010017 [OPEN ACCESS]
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Zhou, Q; Zhang, F; Kerbl-Knapp, J; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T Phosphatidylethanolamine N-Methyltransferase Knockout Modulates Metabolic Changes in Aging Mice.
BIOMOLECULES. 2022; 12(9): Doi: 10.3390/biom12091270 [OPEN ACCESS]
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Zügner, E; Yang, HC; Kotzbeck, P; Boulgaropoulos, B; Sourij, H; Hagvall, S; Elmore, CS; Esterline, R; Moosmang, S; Oscarsson, J; Pieber, TR; Peng, XR; Magnes, C Differential In Vitro Effects of SGLT2 Inhibitors on Mitochondrial Oxidative Phosphorylation, Glucose Uptake and Cell Metabolism.
Int J Mol Sci. 2022; 23(14): Doi: 10.3390/ijms23147966 [OPEN ACCESS]
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2021

Ailioaie, LM; Litscher, G Probiotics, Photobiomodulation, and Disease Management: Controversies and Challenges.
Int J Mol Sci. 2021; 22(9): Doi: 10.3390/ijms22094942 [OPEN ACCESS]
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Amrein, K; Lasky-Su, JA; Dobnig, H; Christopher, KB Metabolomic basis for response to high dose vitamin D in critical illness.
Clin Nutr. 2021; 40(4):2053-2060 Doi: 10.1016/j.clnu.2020.09.028 [OPEN ACCESS]
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Bartenbach, L; Karall, T; Koch, J; Keller, MA; Oberacher, H; Scholl-Bürgi, S; Karall, D; Oemer, G; Baumgartner, D; Meinel, K; Aly, S; Odri-Komazec, I; Geiger, R; Michel, M Amino Acid and Phospholipid Metabolism as an Indicator of Inflammation and Subtle Cardiomyopathy in Patients with Marfan Syndrome.
Metabolites. 2021; 11(12): Doi: 10.3390/metabo11120805 [OPEN ACCESS]
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Bischof, H; Burgstaller, S; Springer, A; Matt, L; Rauter, T; Bachkönig, OA; Schmidt, T; Groschner, K; Schindl, R; Madl, T; Plesnila, N; Lukowski, R; Graier, WF; Malli, R Potassium ions promote hexokinase-II dependent glycolysis.
iScience. 2021; 24(4): 102346-102346. Doi: 10.1016/j.isci.2021.102346 [OPEN ACCESS]
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Chary, S; Amrein, K; Lasky-Su, JA; Dobnig, H; Christopher, KB Metabolomic differences between critically Ill women and men.
Sci Rep. 2021; 11(1):3951-3951 Doi: 10.1038/s41598-021-83602-5 [OPEN ACCESS]
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Gibb, AA; Murray, EK; Eaton, DM; Huynh, AT; Tomar, D; Garbincius, JF; Kolmetzky, DW; Berretta, RM; Wallner, M; Houser, SR; Elrod, JW Molecular Signature of HFpEF: Systems Biology in a Cardiac-Centric Large Animal Model.
JACC Basic Transl Sci. 2021; 6(8):650-672 Doi: 10.1016/j.jacbts.2021.07.004 [OPEN ACCESS]
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Kobayashi, H; Amrein, K; Lasky-Su, JA; Christopher, KB Procalcitonin metabolomics in the critically ill reveal relationships between inflammation intensity and energy utilization pathways.
Sci Rep. 2021; 11(1):23194 Doi: 10.1038/s41598-021-02679-0 [OPEN ACCESS]
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Köfeler, HC; Ahrends, R; Baker, ES; Ekroos, K; Han, X; Hoffmann, N; Holčapek, M; Wenk, MR; Liebisch, G Recommendations for good practice in MS-based lipidomics.
J Lipid Res. 2021; 62: 100138 Doi: 10.1016/j.jlr.2021.100138 [OPEN ACCESS]
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Kozar, N; Kruusmaa, K; Dovnik, A; Bitenc, M; Argamasilla, R; Adsuar, A; Goswami, N; Takač, I; Arko, D Identification of novel diagnostic biomarkers in endometrial cancer using targeted metabolomic profiling.
Adv Med Sci. 2021; 66(1):46-51 Doi: 10.1016/j.advms.2020.12.001
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Kumpitsch, C; Fischmeister, FPS; Mahnert, A; Lackner, S; Wilding, M; Sturm, C; Springer, A; Madl, T; Holasek, S; Högenauer, C; Berg, IA; Schoepf, V; Moissl-Eichinger, C Reduced B12 uptake and increased gastrointestinal formate are associated with archaeome-mediated breath methane emission in humans.
Microbiome. 2021; 9(1):193 Doi: 10.1186/s40168-021-01130-w [OPEN ACCESS]
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Määttä, AM; Salminen, A; Pietiäinen, M; Leskelä, J; Palviainen, T; Sattler, W; Sinisalo, J; Salomaa, V; Kaprio, J; Pussinen, PJ Endotoxemia is associated with an adverse metabolic profile.
INNATE IMMUN-LONDON. 2021; 27(1): 3-14. Doi: 10.1177/1753425920971702 [OPEN ACCESS]
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Mathis, T; Poms, M; Kofeler, H; Gautschi, M; Plecko, B; Baumgartner, MR; Hochuli, M Untargeted plasma metabolomics identifies broad metabolic perturbations in glycogen storage disease type I
J INHERIT METAB DIS. 2021; Doi: 10.1002/jimd.12451 [OPEN ACCESS]
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Reisinger, AC; Posch, F; Hackl, G; Marsche, G; Sourij, H; Bourgeois, B; Eller, K; Madl, T; Eller, P Branched-Chain Amino Acids Can Predict Mortality in ICU Sepsis Patients.
Nutrients. 2021; 13(9): Doi: 10.3390/nu13093106 [OPEN ACCESS]
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Ryan, DG; Yang, M; Prag, HA; Blanco, GR; Nikitopoulou, E; Segarra-Mondejar, M; Powell, CA; Young, T; Burger, N; Miljkovic, JL; Minczuk, M; Murphy, MP; von, Kriegsheim, A; Frezza, C Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism.
Elife. 2021; 10: Doi: 10.7554/eLife.72593 [OPEN ACCESS]
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Streese, L; Springer, AM; Deiseroth, A; Carrard, J; Infanger, D; Schmaderer, C; Schmidt-Trucksaess, A; Madl, T; Hanssen, H Metabolic profiling links cardiovascular risk and vascular end organ damage
ATHEROSCLEROSIS. 2021; 331: 45-53. Doi: 10.1016/j.atherosclerosis.2021.07.005 [OPEN ACCESS]
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Wang-Kan, X; Rodríguez-Blanco, G; Southam, AD; Winder, CL; Dunn, WB; Ivens, A; Piddock, LJV Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium.
mBio. 2021; 12(2): Doi: 10.1128/mBio.00109-21 [OPEN ACCESS]
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Zhang, F; Kerbl-Knapp, J; Akhmetshina, A; Korbelius, M; Kuentzel, KB; Vujić, N; Hörl, G; Paar, M; Kratky, D; Steyrer, E; Madl, T Tissue-Specific Landscape of Metabolic Dysregulation during Ageing.
Biomolecules. 2021; 11(2): Doi: 10.3390/biom11020235 [OPEN ACCESS]
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Zhang, F; Wang, Y; Chen, G; Li, Z; Xing, X; Putz-Bankuti, C; Stauber, RE; Liu, X; Madl, T Growing Human Hepatocellular Tumors Undergo a Global Metabolic Reprogramming.
Cancers (Basel). 2021; 13(8): Doi: 10.3390/cancers13081980 [OPEN ACCESS]
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2020

Blomme, A; Ford, CA; Mui, E; Patel, R; Ntala, C; Jamieson, LE; Planque, M; McGregor, GH; Peixoto, P; Hervouet, E; Nixon, C; Salji, M; Gaughan, L; Markert, E; Repiscak, P; Sumpton, D; Blanco, GR; Lilla, S; Kamphorst, JJ; Graham, D; Faulds, K; MacKay, GM; Fendt, SM; Zanivan, S; Leung, HY 2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.
Nat Commun. 2020; 11(1):2508 Doi: 10.1038/s41467-020-16126-7 [OPEN ACCESS]
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Fellinger, P; Wolf, P; Pfleger, L; Krumpolec, P; Krssak, M; Klavins, K; Wolfsberger, S; Micko, A; Carey, P; Gürtl, B; Vila, G; Raber, W; Fürnsinn, C; Scherer, T; Trattnig, S; Kautzky-Willer, A; Krebs, M; Winhofer, Y Increased ATP synthesis might counteract hepatic lipid accumulation in acromegaly.
JCI Insight. 2020; 5(5): Doi: 10.1172/jci.insight.134638 [OPEN ACCESS]
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Kvietkauskas, M; Zitkute, V; Leber, B; Strupas, K; Stiegler, P; Schemmer, P The Role of Metabolomics in Current Concepts of Organ Preservation.
Int J Mol Sci. 2020; 21(18): Doi: 10.3390/ijms21186607 [OPEN ACCESS]
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Moreau, R; Clària, J; Aguilar, F; Fenaille, F; Lozano, JJ; Junot, C; Colsch, B; Caraceni, P; Trebicka, J; Pavesi, M; Alessandria, C; Nevens, F; Saliba, F; Welzel, TM; Albillos, A; Gustot, T; Fernández, J; Moreno, C; Baldassarre, M; Zaccherini, G; Piano, S; Montagnese, S; Vargas, V; Genescà, J; Solà, E; Bernal, W; Butin, N; Hautbergue, T; Cholet, S; Castelli, F; Jansen, C; Steib, C; Campion, D; Mookerjee, R; Rodríguez-Gandía, M; Soriano, G; Durand, F; Benten, D; Bañares, R; Stauber, RE; Gronbaek, H; Coenraad, MJ; Ginès, P; Gerbes, A; Jalan, R; Bernardi, M; Arroyo, V; Angeli, P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair; European Foundation for the Study of Chronic Liver Failure (EF Clif) Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF.
J Hepatol. 2020; 72(4):688-701 Doi: 10.1016/j.jhep.2019.11.009 [OPEN ACCESS]
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Oizel, K; Tait-Mulder, J; Fernandez-de-Cossio-Diaz, J; Pietzke, M; Brunton, H; Lilla, S; Dhayade, S; Athineos, D; Blanco, GR; Sumpton, D; Mackay, GM; Blyth, K; Zanivan, SR; Meiser, J; Vazquez, A Formate induces a metabolic switch in nucleotide and energy metabolism.
Cell Death Dis. 2020; 11(5):310 Doi: 10.1038/s41419-020-2523-z [OPEN ACCESS]
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Ott, E; Kawaguchi, Y; Kölbl, D; Rabbow, E; Rettberg, P; Mora, M; Moissl-Eichinger, C; Weckwerth, W; Yamagishi, A; Milojevic, T Molecular repertoire of Deinococcus radiodurans after 1 year of exposure outside the International Space Station within the Tanpopo mission.
Microbiome. 2020; 8(1):150-150 Doi: 10.1186/s40168-020-00927-5 [OPEN ACCESS]
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Thumann, TA; Pferschy-Wenzig, EM; Aziz-Kalbhenn, H; Ammar, RM; Rabini, S; Moissl-Eichinger, C; Bauer, R Application of an in vitro digestion model to study the metabolic profile changes of an herbal extract combination by UHPLC-HRMS.
Phytomedicine. 2020; 71(1):153221-153221 Doi: 10.1016/j.phymed.2020.153221 [OPEN ACCESS]
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Wilkinson, DJ; Rodriguez-Blanco, G; Dunn, WB; Phillips, BE; Williams, JP; Greenhaff, PL; Smith, K; Gallagher, IJ; Atherton, PJ Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing.
Aging (Albany NY). 2020; 12(13): 12517-12533. Doi: 10.18632/aging.103513 [OPEN ACCESS]
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Züllig, T; Zandl-Lang, M; Trötzmüller, M; Hartler, J; Plecko, B; Köfeler, HC A Metabolomics Workflow for Analyzing Complex Biological Samples Using a Combined Method of Untargeted and Target-List Based Approaches.
Metabolites. 2020; 10(9): Doi: 10.3390/metabo10090342 [OPEN ACCESS]
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2019

Baracco, EE; Castoldi, F; Durand, S; Enot, DP; Tadic, J; Kainz, K; Madeo, F; Chery, A; Izzo, V; Maiuri, MC; Pietrocola, F; Kroemer, G α-Ketoglutarate inhibits autophagy.
Aging (Albany NY). 2019; 11(11):3418-3431 Doi: 10.18632/aging.102001 [OPEN ACCESS]
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Eaton, DM; Wallner, M; Berretta, RM; Bordag, N; Wu, JC; Jeong, MY; Lin, YH; Borghetti, G; Baker, ST; Zhao, HQ; Rainer, PP; Oyama, MA; von Lewinski, D; Mohsin, S; Post, H; Magnes, C; Zugner, E; McKinsey, TA; Wolfson, MR; Houser, SR Histone Deacetylase Inhibition Improves Heart Failure With Preserved Ejection Fraction Cardiopulmonary Phenotype and Induces Metabolomic Switch
CIRC RES. 2019; 125: [Poster]
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Papuc, SM; Abela, L; Steindl, K; Begemann, A; Simmons, TL; Schmitt, B; Zweier, M; Oneda, B; Socher, E; Crowther, LM; Wohlrab, G; Gogoll, L; Poms, M; Seiler, M; Papik, M; Baldinger, R; Baumer, A; Asadollahi, R; Kroell-Seger, J; Schmid, R; Iff, T; Schmitt-Mechelke, T; Otten, K; Hackenberg, A; Addor, MC; Klein, A; Azzarello-Burri, S; Sticht, H; Joset, P; Plecko, B; Rauch, A The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study.
Eur J Hum Genet. 2019; 27(3):408-421 Doi: 10.1038/s41431-018-0299-8 [OPEN ACCESS]
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2018

Baranyi, A; Meinitzer, A; Rothenhäusler, HB; Amouzadeh-Ghadikolai, O; Lewinski, DV; Breitenecker, RJ; Herrmann, M Metabolomics approach in the investigation of depression biomarkers in pharmacologically induced immune-related depression.
PLoS One. 2018; 13(11):e0208238-e0208238 Doi: 10.1371/journal.pone.0208238 [OPEN ACCESS]
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Crowther, LM; Poms, M; Plecko, B Multiomics tools for the diagnosis and treatment of rare neurological disease.
J INHERIT METAB DIS. 2018; 41(3): 425-434. Doi: 10.1007/s10545-018-0154-7 [OPEN ACCESS]
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Dyar, KA; Hubert, MJ; Mir, AA; Ciciliot, S; Lutter, D; Greulich, F; Quagliarini, F; Kleinert, M; Fischer, K; Eichmann, TO; Wright, LE; Peña, Paz, MI; Casarin, A; Pertegato, V; Romanello, V; Albiero, M; Mazzucco, S; Rizzuto, R; Salviati, L; Biolo, G; Blaauw, B; Schiaffino, S; Uhlenhaut, NH Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
PLoS Biol. 2018; 16(8): e2005886 Doi: 10.1371/journal.pbio.2005886 [OPEN ACCESS]
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Ramirez, T; Strigun, A; Verlohner, A; Huener, HA; Peter, E; Herold, M; Bordag, N; Mellert, W; Walk, T; Spitzer, M; Jiang, X; Sperber, S; Hofmann, T; Hartung, T; Kamp, H; van Ravenzwaay, B Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.
Arch Toxicol. 2018; 92(2): 893-906. Doi: 10.1007/s00204-017-2079-6 [OPEN ACCESS]
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