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Publikationen

Suchbegriffe: LIPASES, . Treffer: 67

2023

Berger, N; van, der, Wel, T; Hirschmugl, B; Baernthaler, T; Gindlhuber, J; Fawzy, N; Eichmann, T; Birner-Gruenberger, R; Zimmermann, R; van, der, Stelt, M; Wadsack, C Inhibition of diacylglycerol lipase β modulates lipid and endocannabinoid levels in the ex vivo human placenta.
Front Endocrinol (Lausanne). 2023; 14: 1092024 Doi: 10.3389/fendo.2023.1092024 [OPEN ACCESS]
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2022

Berger, N; Allerkamp, H; Wadsack, C Serine Hydrolases in Lipid Homeostasis of the Placenta-Targets for Placental Function?
Int J Mol Sci. 2022; 23(12): 6851 Doi: 10.3390/ijms23126851 [OPEN ACCESS]
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Kuentzel, KB; Bradić, I; Mihalič, ZN; Korbelius, M; Rainer, S; Pirchheim, A; Kargl, J; Kratky, D Dysregulation of Placental Lipid Hydrolysis by High-Fat/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice.
Int J Mol Sci. 2022; 23(20): 12286 Doi: 10.3390/ijms232012286 [OPEN ACCESS]
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2021

Chalhoub, G; Kolleritsch, S; Maresch, LK; Taschler, U; Pajed, L; Tilp, A; Eisner, H; Rosina, P; Kien, B; Radner, FPW; Schicho, R; Oberer, M; Schoiswohl, G; Haemmerle, G Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease.
J Lipid Res. 2021; 62:100075 Doi: 10.1016/j.jlr.2021.100075 [OPEN ACCESS]
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Knuplez, E; Sturm, EM; Marsche, G Emerging Role of Phospholipase-Derived Cleavage Products in Regulating Eosinophil Activity: Focus on Lysophospholipids, Polyunsaturated Fatty Acids and Eicosanoids.
Int J Mol Sci. 2021; 22(9): Doi: 10.3390/ijms22094356 [OPEN ACCESS]
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2020

Knuplez, E; Curcic, S; Theiler, A; Bärnthaler, T; Trakaki, A; Trieb, M; Holzer, M; Heinemann, A; Zimmermann, R; Sturm, EM; Marsche, G Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(7):158686-158686 Doi: 10.1016/j.bbalip.2020.158686 [OPEN ACCESS]
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Knuplez, E; Marsche, G An Updated Review of Pro- and Anti-Inflammatory Properties of Plasma Lysophosphatidylcholines in the Vascular System.
Int J Mol Sci. 2020; 21(12): Doi: 10.3390/ijms21124501 [OPEN ACCESS]
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Wagner, C; Hois, V; Pajed, L; Pusch, LM; Wolinski, H; Trauner, M; Zimmermann, R; Taschler, U; Lass, A Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(8): 158730-158730. Doi: 10.1016/j.bbalip.2020.158730 [OPEN ACCESS]
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2019

Godoy, CA; Klett, J; Di, Geronimo, B; Hermoso, JA; Guisán, JM; Carrasco-López, C Disulfide Engineered Lipase to Enhance the Catalytic Activity: A Structure-Based Approach on BTL2.
Int J Mol Sci. 2019; 20(21): Doi: 10.3390/ijms20215245 [OPEN ACCESS]
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2018

Bhutada, G; Kavšček, M; Hofer, F; Gogg-Fassolter, G; Schweiger, M; Darnhofer, B; Kordiš, D; Birner-Gruenberger, R; Natter, K Characterization of a lipid droplet protein from Yarrowia lipolytica that is required for its oleaginous phenotype.
Biochim Biophys Acta Mol Cell Biol Lipids. 2018; 1863(10):1193-1205 Doi: 10.1016/j.bbalip.2018.07.010 [OPEN ACCESS]
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2017

Curcic, S; Holzer, M; Pasterk, L; Knuplez, E; Eichmann, TO; Frank, S; Zimmermann, R; Schicho, R; Heinemann, A; Marsche, G Secretory phospholipase A₂ modified HDL rapidly and potently suppresses platelet activation.
Sci Rep. 2017; 7(1):8030-8030 Doi: 10.1038/s41598-017-08136-1 [OPEN ACCESS]
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Riederer, M; Lechleitner, M; Köfeler, H; Frank, S Reduced expression of adipose triglyceride lipase decreases arachidonic acid release and prostacyclin secretion in human aortic endothelial cells.
Arch Physiol Biochem. 2017; 123(4):249-253 Doi: 10.1080/13813455.2017.1309052 [OPEN ACCESS]
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2016

Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochim Biophys Acta. 2016; 1861(5):462-470 Doi: 10.1016/j.bbalip.2016.02.005 [OPEN ACCESS]
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Herrera, E; Desoye, G Maternal and fetal lipid metabolism under normal and gestational diabetic conditions.
Horm Mol Biol Clin Investig. 2016; 26(2):109-127 Doi: 10.1515/hmbci-2015-0025 [OPEN ACCESS]
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Klein, I; Klug, L; Schmidt, C; Zandl, M; Korber, M; Daum, G; Athenstaedt, K Regulation of the yeast triacylglycerol lipases Tgl4p and Tgl5p by the presence/absence of nonpolar lipids.
Mol Biol Cell. 2016; 27(13):2014-2024 Doi: 10.1091/mbc.E15-09-0633 [OPEN ACCESS]
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Leis, HJ; Windischhofer, W Calcium-independent phospholipases A2 in murine osteoblastic cells and their inhibition by bromoenol lactone: impact on arachidonate dynamics and prostaglandin synthesis.
J Enzyme Inhib Med Chem. 2016; 31(6):1203-1213 Doi: 10.3109/14756366.2015.1114929 [OPEN ACCESS]
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2015

Jaeger, D; Schoiswohl, G; Hofer, P; Schreiber, R; Schweiger, M; Eichmann, TO; Pollak, NM; Poecher, N; Grabner, GF; Zierler, KA; Eder, S; Kolb, D; Radner, FP; Preiss-Landl, K; Lass, A; Zechner, R; Kershaw, EE; Haemmerle, G Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.
J Hepatol. 2015; 63(2):437-45 Doi: 10.1016/j.jhep.2015.02.035 [OPEN ACCESS]
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2014

Dichlberger, A; Schlager, S; Maaninka, K; Schneider, WJ; Kovanen, PT Adipose triglyceride lipase regulates eicosanoid production in activated human mast cells.
J Lipid Res. 2014; 55(12):2471-2478 Doi: 10.1194/jlr.M048553 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Trauner, M Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD.
Trends Endocrinol Metab. 2014; 25(11):576-585 Doi: 10.1016/j.tem.2014.08.001
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Jha, P; Knopf, A; Koefeler, H; Mueller, M; Lackner, C; Hoefler, G; Claudel, T; Trauner, M; Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).
BBA-MOL BASIS DIS. 2014; 1842(7): 959-970. Doi: 10.1016/j.bbadis.2014.02.012 [OPEN ACCESS]
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Karimi, E; Karkhane, AA; Yakhchali, B; Shamsara, M; Aminzadeh, S; Torktaz, I; Hosseini, M; Safari, Z Study of the effect of F17A mutation on characteristics of Bacillus thermocatenulatus lipase expressed in Pichia pastoris using in silico and experimental methods.
Biotechnol Appl Biochem. 2014; 61(3): 264-273. Doi: 10.1002/bab.1164
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2013

Das, SK; Hoefler, G The role of triglyceride lipases in cancer associated cachexia.
Trends Mol Med. 2013; 19(5):292-301 Doi: 10.1016/j.molmed.2013.02.006 [OPEN ACCESS]
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Hosseini, M; Karkhane, AA; Yakhchali, B; Shamsara, M; Aminzadeh, S; Morshedi, D; Haghbeen, K; Torktaz, I; Karimi, E; Safari, Z In silico and experimental characterization of chimeric Bacillus thermocatenulatus lipase with the complete conserved pentapeptide of Candida rugosa lipase.
Appl Biochem Biotechnol. 2013; 169(3): 773-785. Doi: 10.1007/s12010-012-0014-0
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Ploier, B; Scharwey, M; Koch, B; Schmidt, C; Schatte, J; Rechberger, G; Kollroser, M; Hermetter, A; Daum, G Screening for hydrolytic enzymes reveals Ayr1p as a novel triacylglycerol lipase in Saccharomyces cerevisiae.
J Biol Chem. 2013; 288(50):36061-36072 Doi: 10.1074/jbc.M113.509927 [OPEN ACCESS]
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Rengachari, S; Aschauer, P; Schittmayer, M; Mayer, N; Gruber, K; Breinbauer, R; Birner-Gruenberger, R; Dreveny, I; Oberer, M Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase.
J Biol Chem. 2013; 288(43):31093-31104 Doi: 10.1074/jbc.M113.491415 [OPEN ACCESS]
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2012

Lasa, A; Schweiger, M; Kotzbeck, P; Churruca, I; Simón, E; Zechner, R; Portillo, MP Resveratrol regulates lipolysis via adipose triglyceride lipase.
J Nutr Biochem. 2012; 23(4): 379-384. Doi: 10.1016/j.jnutbio.2010.12.014
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Rengachari, S; Bezerra, GA; Riegler-Berket, L; Gruber, CC; Sturm, C; Taschler, U; Boeszoermenyi, A; Dreveny, I; Zimmermann, R; Gruber, K; Oberer, M The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes.
Biochim Biophys Acta. 2012; 1821(7): 1012-1021. Doi: 10.1016/j.bbalip.2012.04.006 [OPEN ACCESS]
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Schittmayer, M; Birner-Gruenberger, R Lipolytic proteomics.
Mass Spectrom Rev. 2012; 31(5):570-582 Doi: 10.1002/mas.20355
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Viertler, M; Schittmayer, M; Birner-Gruenberger, R Activity based subcellular resolution imaging of lipases.
Bioorg Med Chem. 2012; 20(2):628-632 Doi: 10.1016/j.bmc.2011.04.018
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2011

Das, SK; Eder, S; Schauer, S; Diwoky, C; Temmel, H; Guertl, B; Gorkiewicz, G; Tamilarasan, KP; Kumari, P; Trauner, M; Zimmermann, R; Vesely, P; Haemmerle, G; Zechner, R; Hoefler, G Adipose triglyceride lipase contributes to cancer-associated cachexia.
Science. 2011; 333(6039):233-238 Doi: 10.1126/science.1198973 [OPEN ACCESS]
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Etschmaier, K; Becker, T; Eichmann, TO; Schweinzer, C; Scholler, M; Tam-Amersdorfer, C; Poeckl, M; Schuligoi, R; Kober, A; Chirackal, Manavalan, AP; Rechberger, GN; Streith, IE; Zechner, R; Zimmermann, R; Panzenboeck, U Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.
J Neurochem. 2011; 119(5):1016-28 Doi: 10.1111/j.1471-4159.2011.07498.x [OPEN ACCESS]
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Riegler, B; Besenboeck, C; Bauer, R; Nimpf, J; Schneider, WJ Enzymes involved in hepatic acylglycerol metabolism in the chicken.
Biochem Biophys Res Commun. 2011; 406(2): 257-261. Doi: 10.1016/j.bbrc.2011.02.029
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2010

Schicher, M; Morak, M; Birner-Gruenberger, R; Kayer, H; Stojcic, B; Rechberger, GN; Kollroser, M; Hermetter, A Functional proteomic analysis of lipases and esterases in cultured human adipocytes.
J Proteome Res. 2010; 9(12): 6334-6344. Doi: 10.1021/pr1005795
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2009

Morak, M; Schmidinger, H; Krempl, P; Rechberger, G; Kollroser, M; Birner-Gruenberger, R; Hermetter, A Differential activity-based gel electrophoresis for comparative analysis of lipolytic and esterolytic activities.
J Lipid Res. 2009; 50(7): 1281-1292. Doi: 10.1194/jlr.M800566-JLR200 [OPEN ACCESS]
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Rohban, R; Amoozegar, MA; Ventosa, A Screening and isolation of halophilic bacteria producing extracellular hydrolyses from Howz Soltan Lake, Iran.
J Ind Microbiol Biotechnol. 2009; 36(3):333-340 Doi: 10.1007/s10295-008-0500-0
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Schicher, M; Kollroser, M; Hermetter, A Mapping the lipolytic proteome of adipose tissue using fluorescent suicide inhibitors.
Methods Mol Biol. 2009; 579: 497-511. Doi: 10.1007/978-1-60761-322-0_25
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Schittmayer, M; Birner-Gruenberger, R Functional proteomics in lipid research: lipases, lipid droplets and lipoproteins.
J Proteomics. 2009; 72(6): 1006-1018. Doi: 10.1016/j.jprot.2009.05.006
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2008

Birner-Gruenberger, R; Susani-Etzerodt, H; Kollroser, M; Rechberger, GN; Hermetter, A Lipolytic and esterolytic activity-based profiling of murine liver.
Proteomics. 2008; 8(17): 3645-3656. Doi: 10.1002/pmic.200800191
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Pinent, M; Hackl, H; Burkard, TR; Prokesch, A; Papak, C; Scheideler, M; Hämmerle, G; Zechner, R; Trajanoski, Z; Strauss, JG Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice.
Genomics. 2008; 92(1): 26-32. Doi: 10.1016/j.ygeno.2008.03.010 [OPEN ACCESS]
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Schweiger, M; Schoiswohl, G; Lass, A; Radner, FP; Haemmerle, G; Malli, R; Graier, W; Cornaciu, I; Oberer, M; Salvayre, R; Fischer, J; Zechner, R; Zimmermann, R The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding.
J Biol Chem. 2008; 283(25): 17211-17220. Doi: 10.1074/jbc.M710566200 [OPEN ACCESS]
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2007

Birner-Gruenberger, R; Hermetter, A Activity-based proteomics of lipolytic enzymes.
Curr Drug Discov Technol. 2007; 4(1): 1-11. Doi: 10.2174/157016307781115458
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Daum, G; Wagner, A; Czabany, T; Athenstaedt, K Dynamics of neutral lipid storage and mobilization in yeast.
Biochimie. 2007; 89(2): 243-248. Doi: 10.1016/j.biochi.2006.06.018
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Daum, G; Wagner, A; Czabany, T; Grillitsch, K; Athenstaedt, K Lipid storage and mobilization pathways in yeast.
Novartis Found Symp. 2007; 286(25):142-151 Doi: 10.1002/9780470985571.ch12
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2006

Haemmerle, G; Lass, A; Zimmermann, R; Gorkiewicz, G; Meyer, C; Rozman, J; Heldmaier, G; Maier, R; Theussl, C; Eder, S; Kratky, D; Wagner, EF; Klingenspor, M; Hoefler, G; Zechner, R Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
SCIENCE. 2006; 312: 734-737. Doi: 10.1126/science.1123965 [OPEN ACCESS]
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Köffel, R; Schneiter, R Yeh1 constitutes the major steryl ester hydrolase under heme-deficient conditions in Saccharomyces cerevisiae.
Eukaryot Cell. 2006; 5(7):1018-1025 Doi: 10.1128/EC.00002-06 [OPEN ACCESS]
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Pagler, TA; Golsabahi, S; Doringer, M; Rhode, S; Schütz, GJ; Pavelka, M; Wadsack, C; Gauster, M; Lohninger, A; Laggner, H; Strobl, W; Stangl, H A Chinese hamster ovarian cell line imports cholesterol by high density lipoprotein degradation.
J Biol Chem. 2006; 281(50): 38159-38171. Doi: 10.1074/jbc.M603334200 [OPEN ACCESS]
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Schmidinger, H; Susani-Etzerodt, H; Birner-Gruenberger, R; Hermetter, A Inhibitor and protein microarrays for activity-based recognition of lipolytic enzymes.
Chembiochem. 2006; 7(3): 527-534. Doi: 10.1002/cbic.200500276
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Susani-Etzerodt, H; Schmidinger, H; Riesenhuber, G; Birner-Gruenberger, R; Hermetter, A A versatile library of activity-based probes for fluorescence detection and/or affinity isolation of lipolytic enzymes.
Chem Phys Lipids. 2006; 144(1): 60-68. Doi: 10.1016/j.chemphyslip.2006.06.018
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2005

Birner-Gruenberger, R; Susani-Etzerodt, H; Waldhuber, M; Riesenhuber, G; Schmidinger, H; Rechberger, G; Kollroser, M; Strauss, JG; Lass, A; Zimmermann, R; Haemmerle, G; Zechner, R; Hermetter, A The lipolytic proteome of mouse adipose tissue.
MOL CELL PROTEOMICS. 2005; 4(11): 1710-1717. Doi: 10.1074/mcp.M500062-MCP200 [OPEN ACCESS]
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Gauster, M; Rechberger, G; Sovic, A; Hörl, G; Steyrer, E; Sattler, W; Frank, S Endothelial lipase releases saturated and unsaturated fatty acids of high density lipoprotein phosphatidylcholine.
J LIPID RES. 2005; 46: 1517-1525. Doi: 10.1194/jlr.M500054-JLR200 [OPEN ACCESS]
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