Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: INSULIN SIGNALING, . Treffer: 22

2023

Liebscher, G; Vujic, N; Schreiber, R; Heine, M; Krebiehl, C; Duta-Mare, M; Lamberti, G; de, Smet, CH; Hess, MW; Eichmann, TO; Hölzl, S; Scheja, L; Heeren, J; Kratky, D; Huber, LA The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
Mol Metab. 2023; 101705 Doi: 10.1016/j.molmet.2023.101705
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2022

Abdellatif, M; Eisenberg, T; Heberle, AM; Thedieck, K; Kroemer, G; Sedej, S Cardiac PI3K p110 alpha attenuation delays aging and extends lifespan
CELL STRESS. 2022; 6(8): 72-75. Doi: 10.15698/cst2022.08.270 [OPEN ACCESS]
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Abdellatif, M; Madeo, F; Kroemer, G; Sedej, S Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Autophagy. 2022; 18(10):2500-2502 Doi: 10.1080/15548627.2022.2095835 [OPEN ACCESS]
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Oster, M; Galhuber, M; Krstic, J; Steinhoff, JS; Lenihan-Geels, G; Wulff, S; Kiefer, MF; Petricek, KM; Wowro, SJ; Flores, RE; Yang, N; Li, C; Meng, Y; Reinisch, I; Sommerfeld, M; Weger, S; Habisch, H; Madl, T; Schulz, TJ; Prokesch, A; Schupp, M Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis.
J Biol Chem. 2022; 298(9):102287 Doi: 10.1016/j.jbc.2022.102287 [OPEN ACCESS]
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Pusch, LM; Riegler-Berket, L; Oberer, M; Zimmermann, R; Taschler, U α/β-Hydrolase Domain-Containing 6 (ABHD6)- A Multifunctional Lipid Hydrolase.
Metabolites. 2022; 12(8): Doi: 10.3390/metabo12080761 [OPEN ACCESS]
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2021

Pajed, L; Taschler, U; Tilp, A; Hofer, P; Kotzbeck, P; Kolleritsch, S; Radner, FPW; Pototschnig, I; Wagner, C; Schratter, M; Eder, S; Huetter, S; Schreiber, R; Haemmerle, G; Eichmann, TO; Schweiger, M; Hoefler, G; Kershaw, EE; Lass, A; Schoiswohl, G Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Commun Biol. 2021; 4(1):323 Doi: 10.1038/s42003-021-01858-z [OPEN ACCESS]
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2019

Gali, CC; Fanaee-Danesh, E; Zandl-Lang, M; Albrecher, NM; Tam-Amersdorfer, C; Stracke, A; Sachdev, V; Reichmann, F; Sun, Y; Avdili, A; Reiter, M; Kratky, D; Holzer, P; Lass, A; Kandimalla, KK; Panzenboeck, U Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Mol Cell Neurosci. 2019; 99: 103390-103390. Doi: 10.1016/j.mcn.2019.103390 [OPEN ACCESS]
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Ip, CK; Zhang, L; Farzi, A; Qi, Y; Clarke, I; Reed, F; Shi, YC; Enriquez, R; Dayas, C; Graham, B; Begg, D; Brüning, JC; Lee, NJ; Hernandez-Sanchez, D; Gopalasingam, G; Koller, J; Tasan, R; Sperk, G; Herzog, H Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions.
Cell Metab. 2019; 30(1):111-128 Doi: 10.1016/j.cmet.2019.04.001 [OPEN ACCESS]
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Roudnicky, F; Lan, Y; Friesen, M; Dernick, G; Zhang, JD; Staempfli, A; Bordag, N; Wagner-Golbs, A; Christensen, K; Ebeling, M; Graf, M; Burcin, M; Meyer, CA; Cowan, CA; Patsch, C Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype.
Int J Mol Sci. 2019; 20(24): Doi: 10.3390/ijms20246201 [OPEN ACCESS]
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2018

D'Souza, K; Nzirorera, C; Cowie, AM; Varghese, GP; Trivedi, P; Eichmann, TO; Biswas, D; Touaibia, M; Morris, AJ; Aidinis, V; Kane, DA; Pulinilkunnil, T; Kienesberger, PC Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism.
J Lipid Res. 2018; 59(10): 1805-1817. Doi: 10.1194/jlr.M082008 [OPEN ACCESS]
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Xia, W; Pessentheiner, AR; Hofer, DC; Amor, M; Schreiber, R; Schoiswohl, G; Eichmann, TO; Walenta, E; Itariu, B; Prager, G; Hackl, H; Stulnig, T; Kratky, D; Rülicke, T; Bogner-Strauss, JG Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.
Cell Rep. 2018; 23(7):1948-1961 Doi: 10.1016/j.celrep.2018.04.055 [OPEN ACCESS]
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2017

Heier, C; Kien, B; Huang, F; Eichmann, TO; Xie, H; Zechner, R; Chang, PA The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain.
J Biol Chem. 2017; 292(46): 19087-19098. Doi: 10.1074/jbc.M117.792978 [OPEN ACCESS]
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Mueller, KM; Hartmann, K; Kaltenecker, D; Vettorazzi, S; Bauer, M; Mauser, L; Amann, S; Jall, S; Fischer, K; Esterbauer, H; Müller, TD; Tschöp, MH; Magnes, C; Haybaeck, J; Scherer, T; Bordag, N; Tuckermann, JP; Moriggl, R Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Diabetes. 2017; 66(2):272-286 Doi: 10.2337/db16-0381 [OPEN ACCESS]
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2015

Scazzocchio, B; Varì, R; Filesi, C; Del Gaudio, I; D'Archivio, M; Santangelo, C; Iacovelli, A; Galvano, F; Pluchinotta, FR; Giovannini, C; Masella, R Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity.
Mol Nutr Food Res. 2015; 59(8):1472-1481 Doi: 10.1002/mnfr.201400816
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2013

Duszka, K; Bogner-Strauss, JG; Hackl, H; Rieder, D; Neuhold, C; Prokesch, A; Trajanoski, Z; Krogsdam, AM Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue.
Mol Endocrinol. 2013; 27(1): 135-149. Doi: 10.1210/me.2012-1248 [OPEN ACCESS]
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Putker, M; Madl, T; Vos, HR; de Ruiter, H; Visscher, M; van den Berg, MC; Kaplan, M; Korswagen, HC; Boelens, R; Vermeulen, M; Burgering, BM; Dansen, TB Redox-dependent control of FOXO/DAF-16 by transportin-1.
Mol Cell. 2013; 49(4): 730-742. Doi: 10.1016/j.molcel.2012.12.014 [OPEN ACCESS]
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Riehle, C; Wende, AR; Sena, S; Pires, KM; Pereira, RO; Zhu, Y; Bugger, H; Frank, D; Bevins, J; Chen, D; Perry, CN; Dong, XC; Valdez, S; Rech, M; Sheng, X; Weimer, BC; Gottlieb, RA; White, MF; Abel, ED Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
J Clin Invest. 2013; 123(12): 5319-5333. Doi: 10.1172/JCI71171 [OPEN ACCESS]
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2012

Bugger, H; Riehle, C; Jaishy, B; Wende, AR; Tuinei, J; Chen, D; Soto, J; Pires, KM; Boudina, S; Theobald, HA; Luptak, I; Wayment, B; Wang, X; Litwin, SE; Weimer, BC; Abel, ED Genetic loss of insulin receptors worsens cardiac efficiency in diabetes.
J Mol Cell Cardiol. 2012; 52(5): 1019-1026. Doi: 10.1016/j.yjmcc.2012.02.001 [OPEN ACCESS]
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2010

Wallner-Liebmann, S; Koschutnig, K; Reishofer, G; Sorantin, E; Blaschitz, B; Kruschitz, R; Unterrainer, HF; Gasser, R; Freytag, F; Bauer-Denk, C; Schienle, A; Schäfer, A; Mangge, H Insulin and hippocampus activation in response to images of high-calorie food in normal weight and obese adolescents.
Obesity (Silver Spring). 2010; 18(8):1552-1557 Doi: 10.1038/oby.2010.26 [OPEN ACCESS]
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2009

Boudina, S; Bugger, H; Sena, S; O'Neill, BT; Zaha, VG; Ilkun, O; Wright, JJ; Mazumder, PK; Palfreyman, E; Tidwell, TJ; Theobald, H; Khalimonchuk, O; Wayment, B; Sheng, X; Rodnick, KJ; Centini, R; Chen, D; Litwin, SE; Weimer, BE; Abel, ED Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.
Circulation. 2009; 119(9): 1272-1283. Doi: 10.1161/CIRCULATIONAHA.108.792101 [OPEN ACCESS]
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Kienesberger, PC; Lee, D; Pulinilkunnil, T; Brenner, DS; Cai, L; Magnes, C; Koefeler, HC; Streith, IE; Rechberger, GN; Haemmerle, G; Flier, JS; Zechner, R; Kim, YB; Kershaw, EE Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling.
J Biol Chem. 2009; 284(44): 30218-30229. Doi: 10.1074/jbc.M109.047787 [OPEN ACCESS]
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Liu, S; Okada, T; Assmann, A; Soto, J; Liew, CW; Bugger, H; Shirihai, OS; Abel, ED; Kulkarni, RN Insulin signaling regulates mitochondrial function in pancreatic beta-cells.
PLoS One. 2009; 4(11): e7983-e7983. Doi: 10.1371/journal.pone.0007983 [OPEN ACCESS]
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