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Publikationen

Suchbegriffe: IN VITRO MODEL, . Treffer: 86

2023

Alonso, N; Meinitzer, A; Fritz-Petrin, E; Enko, D; Herrmann, M Role of Vitamin K in Bone and Muscle Metabolism.
Calcif Tissue Int. 2023; 112(2):178-196 Doi: 10.1007/s00223-022-00955-3 [OPEN ACCESS]
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Hofmann, E; Schwarz, A; Fink, J; Kamolz, LP; Kotzbeck, P Modelling the Complexity of Human Skin In Vitro.
Biomedicines. 2023; 11(3): Doi: 10.3390/biomedicines11030794 [OPEN ACCESS]
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Karner, C; Anders, I; Vejzovic, D; Szkandera, J; Scheipl, S; Deutsch, AJA; Weiss, L; Vierlinger, K; Kolb, D; Kühberger, S; Heitzer, E; Habisch, H; Zhang, F; Madl, T; Reininger-Gutmann, B; Liegl-Atzwanger, B; Rinner, B Targeting epigenetic features in clear cell sarcomas based on patient-derived cell lines.
J Transl Med. 2023; 21(1): 54 Doi: 10.1186/s12967-022-03843-4 [OPEN ACCESS]
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Meindl, C; Absenger-Novak, M; Jeitler, R; Roblegg, E; Frohlich, E Assessment of Carbon Nanotubes on Barrier Function, Ciliary Beating Frequency and Cytokine Release in In Vitro Models of the Respiratory Tract
NANOMATERIALS-BASEL. 2023; 13(4): 682 Doi: 10.3390/nano13040682 [OPEN ACCESS]
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2022

Peterson, JM; Jay, JW; Wang, Y; Joglar, AA; Prasai, A; Palackic, A; Wolf, SE; El, Ayadi, A Galunisertib Exerts Antifibrotic Effects on TGF-β-Induced Fibroproliferative Dermal Fibroblasts.
Int J Mol Sci. 2022; 23(12): Doi: 10.3390/ijms23126689 [OPEN ACCESS]
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Sauler, M; McDonough, JE; Adams, TS; Kothapalli, N; Barnthaler, T; Werder, RB; Schupp, JC; Nouws, J; Robertson, MJ; Coarfa, C; Yang, T; Chioccioli, M; Omote, N; Cosme, C; Poli, S; Ayaub, EA; Chu, SG; Jensen, KH; Gomez, JL; Britto, CJ; Raredon, MSB; Niklason, LE; Wilson, AA; Timshel, PN; Kaminski, N; Rosas, IO Characterization of the COPD alveolar niche using single-cell RNA sequencing.
Nat Commun. 2022; 13(1): 494 Doi: 10.1038/s41467-022-28062-9 [OPEN ACCESS]
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2021

Kocher, F; Tymoszuk, P; Amann, A; Sprung, S; Salcher, S; Daum, S; Haybaeck, J; Rinnerthaler, G; Huemer, F; Kauffmann-Guerrero, D; Tufman, A; Seeber, A; Wolf, D; Pircher, A Deregulated glutamate to pro-collagen conversion is associated with adverse outcome in lung cancer and may be targeted by renin-angiotensin-aldosterone system (RAS) inhibition.
Lung Cancer. 2021; 159: 84-95. Doi: 10.1016/j.lungcan.2021.06.020 [OPEN ACCESS]
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Meindl, C; Öhlinger, K; Zrim, V; Steinkogler, T; Fröhlich, E Screening for Effects of Inhaled Nanoparticles in Cell Culture Models for Prolonged Exposure.
Nanomaterials (Basel). 2021; 11(3): Doi: 10.3390/nano11030606 [OPEN ACCESS]
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Schrom, S; Hebesberger, T; Wallner, SA; Anders, I; Richtig, E; Brandl, W; Hirschmugl, B; Garofalo, M; Bernecker, C; Schlenke, P; Kashofer, K; Wadsack, C; Aigelsreiter, A; Heitzer, E; Riedl, S; Zweytick, D; Kretschmer, N; Richtig, G; Rinner, B MUG Mel3 Cell Lines Reflect Heterogeneity in Melanoma and Represent a Robust Model for Melanoma in Pregnancy.
Int J Mol Sci. 2021; 22(21): Doi: 10.3390/ijms222111318 [OPEN ACCESS]
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2020

Grissenberger, S; Riedl, S; Rinner, B; Leber, R; Zweytick, D Design of human lactoferricin derived antitumor peptides-activity and specificity against malignant melanoma in 2D and 3D model studies.
Biochim Biophys Acta Biomembr. 2020; 183264-183264. Doi: 10.1016/j.bbamem.2020.183264 [OPEN ACCESS]
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Hortobagyi, D; Grossmann, T; Tschernitz, M; Grill, M; Kirsch, A; Gerstenberger, C; Gugatschka, M In vitro mechanical vibration down-regulates pro-inflammatory and pro-fibrotic signaling in human vocal fold fibroblasts.
PLoS One. 2020; 15(11): e0241901-e0241901. Doi: 10.1371/journal.pone.0241901 [OPEN ACCESS]
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Öhlinger, K; Absenger-Novak, M; Meindl, C; Ober, J; Fröhlich, E Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs.
Int J Mol Sci. 2020; 21(21): Doi: 10.3390/ijms21218391 [OPEN ACCESS]
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Parrado-Fernandez, C; Leoni, V; Saeed, A; Rodriguez-Rodriguez, P; Sandebring-Matton, A; Córdoba-Beldad, CM; Bueno, P; Gali, CC; Panzenboeck, U; Cedazo-Minguez, A; Björkhem, I Sex difference in flux of 27-hydroxycholesterol into the brain.
Br J Pharmacol. 2020; 72(2): Doi: 10.1111/bph.15353 [OPEN ACCESS]
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Prasch, J; Bernhart, E; Reicher, H; Kollroser, M; Rechberger, GN; Koyani, CN; Trummer, C; Rech, L; Rainer, PP; Hammer, A; Malle, E; Sattler, W Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21239235 [OPEN ACCESS]
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2018

Bierbaumer, L; Schwarze, UY; Gruber, R; Neuhaus, W Cell culture models of oral mucosal barriers: A review with a focus on applications, culture conditions and barrier properties.
Tissue Barriers. 2018; 6(3): 1479568-1479568. Doi: 10.1080/21688370.2018.1479568 [OPEN ACCESS]
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Fröhlich, E Comparison of conventional and advanced in vitro models in the toxicity testing of nanoparticles.
Artif Cells Nanomed Biotechnol. 2018; 46(sup2):1091-1107 Doi: 10.1080/21691401.2018.1479709 [OPEN ACCESS]
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2017

Caiazzo, A; Caforio, F; Montecinos, G; Muller, LO; Blanco, PJ; Toro, EF Assessment of reduced-order unscented Kalman filter for parameter identification in 1-dimensional blood flow models using experimental data.
Int J Numer Method Biomed Eng. 2017; 33(8):e2843-e2843 Doi: 10.1002/cnm.2843
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Diomede, F; Thangavelu, SR; Merciaro, I; D'Orazio, M; Bramanti, P; Mazzon, E; Trubiani, O Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation.
Eur J Histochem. 2017; 61(3):2826-2826 Doi: 10.4081/ejh.2017.2826 [OPEN ACCESS]
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Gaebler, M; Silvestri, A; Haybaeck, J; Reichardt, P; Lowery, CD; Stancato, LF; Zybarth, G; Regenbrecht, CRA Three-Dimensional Patient-Derived In Vitro Sarcoma Models: Promising Tools for Improving Clinical Tumor Management.
Front Oncol. 2017; 7(10):203-203 Doi: 10.3389/fonc.2017.00203 [OPEN ACCESS]
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Kober, AC; Manavalan, APC; Tam-Amersdorfer, C; Holmér, A; Saeed, A; Fanaee-Danesh, E; Zandl, M; Albrecher, NM; Björkhem, I; Kostner, GM; Dahlbäck, B; Panzenboeck, U Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017; 1862(6):573-588 Doi: 10.1016/j.bbalip.2017.03.003
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Lelu, S; Afadzi, M; Berg, S; Aslund, AK; Torp, SH; Sattler, W; de L Davies, C Primary Porcine Brain Endothelial Cells as In Vitro Model to Study Effects of Ultrasound and Microbubbles on Blood-Brain Barrier Function.
IEEE Trans Ultrason Ferroelectr Freq Control. 2017; 64(1):281-290 Doi: 10.1109/TUFFC.2016.2597004 [OPEN ACCESS]
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Rothbauer, M; Patel, N; Gondola, H; Siwetz, M; Huppertz, B; Ertl, P A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.
Sci Rep. 2017; 7(1):5892-5892 Doi: 10.1038/s41598-017-06364-z [OPEN ACCESS]
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Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; Jandrasits, C; Borodina, T; Amstislavskiy, V; Worth, CL; Schweiger, C; Liebs, S; Lange, M; Warnatz, HJ; Butcher, LM; Barrett, JE; Sultan, M; Wierling, C; Golob-Schwarzl, N; Lax, S; Uranitsch, S; Becker, M; Welte, Y; Regan, JL; Silvestrov, M; Kehler, I; Fusi, A; Kessler, T; Herwig, R; Landegren, U; Wienke, D; Nilsson, M; Velasco, JA; Garin-Chesa, P; Reinhard, C; Beck, S; Schäfer, R; Regenbrecht, CR; Henderson, D; Lange, B; Haybaeck, J; Keilholz, U; Hoffmann, J; Lehrach, H; Yaspo, ML Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nat Commun. 2017; 8(2):14262-14262 Doi: 10.1038/ncomms14262 [OPEN ACCESS]
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Zadora, J; Singh, M; Herse, F; Przybyl, L; Haase, N; Golic, M; Yung, HW; Huppertz, B; Cartwright, JE; Whitley, G; Johnsen, GM; Levi, G; Isbruch, A; Schulz, H; Luft, FC; Müller, DN; Staff, AC; Hurst, LD; Dechend, R; Izsvák, Z Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker.
CIRCULATION. 2017; 136(19): 1824-1839. Doi: 10.1161/CIRCULATIONAHA.117.028110 [OPEN ACCESS]
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2016

Fröhlich, E; Roblegg, E Oral uptake of nanoparticles: human relevance and the role of in vitro systems.
Arch Toxicol. 2016; 90(10):2297-2314 Doi: 10.1007/s00204-016-1765-0 [OPEN ACCESS]
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Gellner, V; Tomazic, PV; Lohberger, B; Meditz, K; Heitzer, E; Mokry, M; Koele, W; Leithner, A; Liegl-Atzwanger, B; Rinner, B Establishment of clival chordoma cell line MUG-CC1 and lymphoblastoid cells as a model for potential new treatment strategies.
Sci Rep. 2016; 6(7):24195-24195 Doi: 10.1038/srep24195 [OPEN ACCESS]
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Graupp, M; Bachna-Rotter, S; Gerstenberger, C; Friedrich, G; Fröhlich-Sorger, E; Kiesler, K; Gugatschka, M The unsolved chapter of vocal fold scars and how tissue engineering could help us solve the problem.
Eur Arch Otorhinolaryngol. 2016; 273(9):2279-2284 Doi: 10.1007/s00405-015-3668-8 [OPEN ACCESS]
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Rolny, IS; Tiscornia, I; Racedo, SM; Pérez, PF; Bollati-Fogolín, M Lactobacillus delbrueckii subsp lactis CIDCA 133 modulates response of human epithelial and dendritic cells infected with Bacillus cereus.
Benef Microbes. 2016; 7(5):749-760 Doi: 10.3920/BM2015.0191
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2015

Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819 Doi: 10.1002/mc.22252 [OPEN ACCESS]
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Graupp, M; Gruber, HJ; Weiss, G; Kiesler, K; Bachna-Rotter, S; Friedrich, G; Gugatschka, M Establishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria.
Laryngoscope. 2015; 125(6):E203-E209 Doi: 10.1002/lary.25103
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Januar, V; Desoye, G; Novakovic, B; Cvitic, S; Saffery, R Epigenetic regulation of human placental function and pregnancy outcome: considerations for causal inference.
AM J OBSTET GYNECOL. 2015; 213(4 Suppl): S182-S196. Doi: 10.1016/j.ajog.2015.07.011
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Jimenez, K; Khare, V; Evstatiev, R; Kulnigg-Dabsch, S; Jambrich, M; Strobl, H; Gasche, C Increased expression of HIF2α during iron deficiency-associated megakaryocytic differentiation.
J Thromb Haemost. 2015; 13(6):1113-1127 Doi: 10.1111/jth.12884 [OPEN ACCESS]
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Leis, HJ; Windischhofer, W Molecular characterisation of group IVA (cytosolic) phospholipase A2 in murine osteoblastic MC3T3-E1 cells.
Protein J. 2015; 34(1):29-34 Doi: 10.1007/s10930-014-9594-6
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Moser, G; Weiss, G; Gauster, M; Sundl, M; Huppertz, B Evidence from the very beginning: endoglandular trophoblasts penetrate and replace uterine glands in situ and in vitro.
Hum Reprod. 2015; 30(12):2747-2757 Doi: 10.1093/humrep/dev266 [OPEN ACCESS]
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2014

Bruns, H; Petrulionis, M; Schultze, D; Al Saeedi, M; Lin, S; Yamanaka, K; Ambrazevičius, M; Strupas, K; Schemmer, P Glycine inhibits angiogenic signaling in human hepatocellular carcinoma cells.
Amino Acids. 2014; 46(4):969-976 Doi: 10.1007/s00726-013-1662-2
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Chirackal Manavalan, AP; Kober, A; Metso, J; Lang, I; Becker, T; Hasslitzer, K; Zandl, M; Fanaee-Danesh, E; Pippal, JB; Sachdev, V; Kratky, D; Stefulj, J; Jauhiainen, M; Panzenboeck, U Phospholipid transfer protein is expressed in cerebrovascular endothelial cells and involved in high density lipoprotein biogenesis and remodeling at the blood-brain barrier.
J Biol Chem. 2014; 289(8):4683-4698 Doi: 10.1074/jbc.M113.499129 [OPEN ACCESS]
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Fröhlich, E; Salar-Behzadi, S Toxicological assessment of inhaled nanoparticles: role of in vivo, ex vivo, in vitro, and in silico studies.
Int J Mol Sci. 2014; 15(3):4795-4822 Doi: 10.3390/ijms15034795 [OPEN ACCESS]
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Helige, C; Ahammer, H; Moser, G; Hammer, A; Dohr, G; Huppertz, B; Sedlmayr, P Distribution of decidual natural killer cells and macrophages in the neighbourhood of the trophoblast invasion front: a quantitative evaluation.
Hum Reprod. 2014; 29(1):8-17 Doi: 10.1093/humrep/det353 [OPEN ACCESS]
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Kleine, M; Worbs, T; Schrem, H; Vondran, FW; Kaltenborn, A; Klempnauer, J; Förster, R; Josenhans, C; Suerbaum, S; Bektas, H Helicobacter hepaticus induces an inflammatory response in primary human hepatocytes.
PLoS One. 2014; 9(6): e99713-e99713. Doi: 10.1371/journal.pone.0099713 [OPEN ACCESS]
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Reisner, A; Maierl, M; Jörger, M; Krause, R; Berger, D; Haid, A; Tesic, D; Zechner, EL Type 1 fimbriae contribute to catheter-associated urinary tract infections caused by Escherichia coli.
J Bacteriol. 2014; 196(5):931-939 Doi: 10.1128/JB.00985-13 [OPEN ACCESS]
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Schimpel, C; Teubl, B; Absenger, M; Meindl, C; Fröhlich, E; Leitinger, G; Zimmer, A; Roblegg, E Development of an advanced intestinal in vitro triple culture permeability model to study transport of nanoparticles.
Mol Pharm. 2014; 11(3):808-818 Doi: 10.1021/mp400507g
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2013

Koenig, S; Schernthaner, M; Maechler, H; Kappe, CO; Glasnov, TN; Hoefler, G; Braune, M; Wittchow, E; Groschner, K A TRPC3 blocker, ethyl-1-(4-(2,3,3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (Pyr3), prevents stent-induced arterial remodeling.
J Pharmacol Exp Ther. 2013; 344(1):33-40 Doi: 10.1124/jpet.112.196832 [OPEN ACCESS]
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König, S; Browne, S; Doleschal, B; Schernthaner, M; Poteser, M; Mächler, H; Wittchow, E; Braune, M; Muik, M; Romanin, C; Groschner, K Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.
Am J Physiol Heart Circ Physiol. 2013; 305(11):H1646-H1657 Doi: 10.1152/ajpheart.00365.2013 [OPEN ACCESS]
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Teubl, BJ; Absenger, M; Fröhlich, E; Leitinger, G; Zimmer, A; Roblegg, E The oral cavity as a biological barrier system: design of an advanced buccal in vitro permeability model.
Eur J Pharm Biopharm. 2013; 84(2):386-393 Doi: 10.1016/j.ejpb.2012.10.021
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2012

Fröhlich, E; Roblegg, E Models for oral uptake of nanoparticles in consumer products.
Toxicology. 2012; 291(1-3):10-17 Doi: 10.1016/j.tox.2011.11.004 [OPEN ACCESS]
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Löffler, T; Flunkert, S; Taub, N; Schofield, EL; Ward, MA; Windisch, M; Hutter-Paier, B Stable mutated tau441 transfected SH-SY5Y cells as screening tool for Alzheimer's disease drug candidates.
J Mol Neurosci. 2012; 47(1): 192-203. Doi: 10.1007/s12031-012-9716-6 [OPEN ACCESS]
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2011

Kienesberger, S; Gorkiewicz, G; Wolinski, H; Zechner, EL New molecular microbiology approaches in the study of Campylobacter fetus.
Microb Biotechnol. 2011; 4(1): 8-19. Doi: 10.1111/j.1751-7915.2010.00173.x [OPEN ACCESS]
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Kittinger, C; Marth, E; Windhager, R; Weinberg, AM; Zarfel, G; Baumert, R; Felisch, S; Kuehn, KD Antimicrobial activity of gentamicin palmitate against high concentrations of Staphylococcus aureus.
J Mater Sci Mater Med. 2011; 22(6):1447-1453 Doi: 10.1007/s10856-011-4333-4
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Orendi, K; Kivity, V; Sammar, M; Grimpel, Y; Gonen, R; Meiri, H; Lubzens, E; Huppertz, B Placental and trophoblastic in vitro models to study preventive and therapeutic agents for preeclampsia
PLACENTA. 2011; 32: S49-S54. Doi: 10.1016/j.placenta.2010.11.023
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Schweinzer, C; Kober, A; Lang, I; Etschmaier, K; Scholler, M; Kresse, A; Sattler, W; Panzenboeck, U Processing of endogenous AβPP in blood-brain barrier endothelial cells is modulated by liver-X receptor agonists and altered cellular cholesterol homeostasis.
J Alzheimers Dis. 2011; 27(2):341-360 Doi: 10.3233/JAD-2011-110854
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