Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: HYPERTROPHY, . Treffer: 209

2023

Crnkovic, S; Rittchen, S; Jandl, K; Gindlhuber, J; Zabini, D; Mutgan, AC; Valzano, F; Boehm, PM; Hoetzenecker, K; Toller, W; Veith, C; Heinemann, A; Schermuly, RT; Olschewski, A; Marsh, LM; Kwapiszewska, G Divergent Roles of Ephrin-B2/EphB4 Guidance System in Pulmonary Hypertension.
Hypertension. 2023; 80(2):e17-e28 Doi: 10.1161/HYPERTENSIONAHA.122.19479
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Messerer, J; Wrede, C; Schipke, J; Brandenberger, C; Abdellatif, M; Eisenberg, T; Madeo, F; Sedej, S; Mühlfeld, C Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice.
J Anat. 2023; 242(1):91-101 Doi: 10.1111/joa.13618 [OPEN ACCESS]
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2022

Abdellatif, M; Madeo, F; Kroemer, G; Sedej, S Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Autophagy. 2022; 18(10):2500-2502 Doi: 10.1080/15548627.2022.2095835 [OPEN ACCESS]
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Abdellatif, M; Trummer-Herbst, V; Heberle, AM; Humnig, A; Pendl, T; Durand, S; Cerrato, G; Hofer, SJ; Islam, M; Voglhuber, J; Ramos, Pittol, JM; Kepp, O; Hoefler, G; Schmidt, A; Rainer, PP; Scherr, D; von, Lewinski, D; Bisping, E; McMullen, JR; Diwan, A; Eisenberg, T; Madeo, F; Thedieck, K; Kroemer, G; Sedej, S Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Circulation. 2022; 145(25):1853-1866 Doi: 10.1161/CIRCULATIONAHA.122.059863 [OPEN ACCESS]
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Brosolo, G; Catena, C; Da, Porto, A; Bulfone, L; Vacca, A; Verheyen, ND; Sechi, LA Differences in Regulation of Cortisol Secretion Contribute to Left Ventricular Abnormalities in Patients With Essential Hypertension.
Hypertension. 2022; 101161HYPERTENSIONAHA12219472 Doi: 10.1161/HYPERTENSIONAHA.122.19472
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Eaton, DM; Berretta, RM; Lynch, JE; Travers, JG; Pfeiffer, RD; Hulke, ML; Zhao, H; Hobby, ARH; Schena, G; Johnson, JP; Wallner, M; Lau, E; Lam, MPY; Woulfe, KC; Tucker, NR; McKinsey, TA; Wolfson, MR; Houser, SR Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF.
Am J Physiol Heart Circ Physiol. 2022; 323(4):H797-H817 Doi: 10.1152/ajpheart.00374.2022 [OPEN ACCESS]
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Ljubojević-Holzer, S; Kraler, S; Djalinac, N; Abdellatif, M; Voglhuber, J; Schipke, J; Schmidt, M; Kling, KM; Franke, GT; Herbst, V; Zirlik, A; von, Lewinski, D; Scherr, D; Rainer, PP; Kohlhaas, M; Nickel, A; Mühlfeld, C; Maack, C; Sedej, S Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Cardiovasc Res. 2022; 118(6):1492-1505 Doi: 10.1093/cvr/cvab112 [OPEN ACCESS]
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Matzer, I; Voglhuber, J; Kiessling, M; Djalinac, N; Trummer-Herbst, V; Mabotuwana, N; Rech, L; Holzer, M; Sossalla, S; Rainer, PP; Zirlik, A; Ljubojevic-Holzer, S β-Adrenergic Receptor Stimulation Maintains NCX-CaMKII Axis and Prevents Overactivation of IL6R-Signaling in Cardiomyocytes upon Increased Workload.
Biomedicines. 2022; 10(7): Doi: 10.3390/biomedicines10071648 [OPEN ACCESS]
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Mogl, AG; Palackic, A; Cambiaso-Daniel, J; Duggan, RP; Vappiani, M; Giraudi, C; Raposio, E; Bertossi, D; Gualdi, A Conchal Excision Techniques in Otoplasty: A Literature Review.
PRS-GLOB OPEN. 2022; 10(6): e4381 Doi: 10.1097/GOX.0000000000004381 [OPEN ACCESS]
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Rech, L; Abdellatif, M; Pöttler, M; Stangl, V; Mabotuwana, N; Hardy, S; Rainer, PP Small molecule STING inhibition improves myocardial infarction remodeling.
Life Sci. 2022; 291:120263 Doi: 10.1016/j.lfs.2021.120263
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Veith, C; Vartürk-Özcan, I; Wujak, M; Hadzic, S; Wu, CY; Knoepp, F; Kraut, S; Petrovic, A; Gredic, M; Pak, O; Brosien, M; Heimbrodt, M; Wilhelm, J; Weisel, FC; Malkmus, K; Schäfer, K; Gall, H; Tello, K; Kosanovic, D; Sydykov, A; Sarybaev, A; Günther, A; Brandes, RP; Seeger, W; Grimminger, F; Ghofrani, HA; Schermuly, RT; Kwapiszewska, G; Sommer, N; Weissmann, N SPARC, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension.
Circulation. 2022; 145(12):916-933 Doi: 10.1161/CIRCULATIONAHA.121.057001
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2021

Al, Kaissi, A; Misof, BM; Laccone, F; Blouin, S; Roschger, P; Kircher, SG; Shboul, M; Mindler, GT; Girsch, W; Ganger, R Clinical Phenotype and Bone Biopsy Characteristics in a Child with Proteus Syndrome.
Calcif Tissue Int. 2021; 109(5):586-595 Doi: 10.1007/s00223-021-00862-z (- Case Report)
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Del, Gaudio, I; Rubinelli, L; Sasset, L; Wadsack, C; Hla, T; Di, Lorenzo, A Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine-1-Phosphate.
J Am Heart Assoc. 2021; 10(14): e021261 Doi: 10.1161/JAHA.121.021261 [OPEN ACCESS]
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Diekmann, F; Chouvarine, P; Sallmon, H; Meyer-Kobbe, L; Kieslich, M; Plouffe, BD; Murthy, SK; Lichtinghagen, R; Legchenko, E; Hansmann, G Soluble Receptor for Advanced Glycation End Products (sRAGE) Is a Sensitive Biomarker in Human Pulmonary Arterial Hypertension.
Int J Mol Sci. 2021; 22(16): Doi: 10.3390/ijms22168591 [OPEN ACCESS]
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Gross, P; Johnson, J; Romero, CM; Eaton, DM; Poulet, C; Sanchez-Alonso, J; Lucarelli, C; Ross, J; Gibb, AA; Garbincius, JF; Lambert, J; Varol, E; Yang, Y; Wallner, M; Feldsott, EA; Kubo, H; Berretta, RM; Yu, D; Rizzo, V; Elrod, J; Sabri, A; Gorelik, J; Chen, X; Houser, SR Interaction of the Joining Region in Junctophilin-2 With the L-Type Ca2+ Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca2+ Dynamics.
Circ Res. 2021; 128(1):92-114 Doi: 10.1161/CIRCRESAHA.119.315715 [OPEN ACCESS]
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Helmstadter, KG; Ljubojevic-Holzer, S; Wood, BM; Taheri, KD; Sedej, S; Erickson, JR; Bossuyt, J; Bers, DM CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes.
Basic Res Cardiol. 2021; 116(1):11-11 Doi: 10.1007/s00395-021-00850-2 [OPEN ACCESS]
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Jakubik, D; Fitas, A; Eyileten, C; Jarosz-Popek, J; Nowak, A; Czajka, P; Wicik, Z; Sourij, H; Siller-Matula, JM; De Rosa, S; Postula, M MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics.
Cardiovasc Diabetol. 2021; 20(1): 55-55. Doi: 10.1186/s12933-021-01245-2 [OPEN ACCESS]
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Le, Ribeuz, H; To, L; Ghigna, MR; Martin, C; Nagaraj, C; Dreano, E; Rucker-Martin, C; Girerd, B; Bouligand, J; Pechoux, C; Lambert, M; Boet, A; Issard, J; Mercier, O; Hoetzenecker, K; Manoury, B; Becq, F; Burgel, PR; Cottart, CH; Olschewski, A; Sermet-Gaudelus, I; Perros, F; Humbert, M; Montani, D; Antigny, F Involvement of CFTR in the pathogenesis of pulmonary arterial hypertension.
Eur Respir J. 2021; 58(5): Doi: 10.1183/13993003.00653-2020
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Weixler, V; Lapusca, R; Grangl, G; Guariento, A; Saeed, MY; Cowan, DB; Del Nido, PJ; McCully, JD; Friehs, I Autogenous mitochondria transplantation for treatment of right heart failure.
J Thorac Cardiovasc Surg. 2021; 162(1):e111-e121-e111-e121 Doi: 10.1016/j.jtcvs.2020.08.011
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2020

Berulava, T; Buchholz, E; Elerdashvili, V; Pena, T; Islam, MR; Lbik, D; Mohamed, BA; Renner, A; von, Lewinski, D; Sacherer, M; Bohnsack, KE; Bohnsack, MT; Jain, G; Capece, V; Cleve, N; Burkhardt, S; Hasenfuss, G; Fischer, A; Toischer, K Changes in m6A RNA methylation contribute to heart failure progression by modulating translation.
Eur J Heart Fail. 2020; 22(1):54-66 Doi: 10.1002/ejhf.1672 [OPEN ACCESS]
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Djalinac, N; Ljubojevic-Holzer, S; Matzer, I; Kolesnik, E; Jandl, K; Lohberger, B; Rainer, P; Heinemann, A; Sedej, S; von, Lewinski, D; Bisping, E The role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodelling.
J Cell Mol Med. 2020; 24(15):8732-8743 Doi: 10.1111/jcmm.15504 [OPEN ACCESS]
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Kunc, V; Štulpa, M; Feigl, G; Neblett, C; Kunc, V; Kachlík, D The superficial anatomical landmarks are not reliable for predicting the recurrent branch of the median nerve.
Surg Radiol Anat. 2020; 42(8):939-943 Doi: 10.1007/s00276-020-02475-x
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Ljubojevic-Holzer, S; Herren, AW; Djalinac, N; Voglhuber, J; Morotti, S; Holzer, M; Wood, BM; Abdellatif, M; Matzer, I; Sacherer, M; Radulovic, S; Wallner, M; Ivanov, M; Wagner, S; Sossalla, S; von Lewinski, D; Pieske, B; Brown, JH; Sedej, S; Bossuyt, J; Bers, DM CaMKIIδC Drives Early Adaptive Ca2+ Change and Late Eccentric Cardiac Hypertrophy.
Circ Res. 2020; 127(9):1159-1178 Doi: 10.1161/CIRCRESAHA.120.316947 [OPEN ACCESS]
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Mühlfeld, C; Rajces, A; Manninger, M; Alogna, A; Wierich, MC; Scherr, D; Post, H; Schipke, J A transmural gradient of myocardial remodeling in early-stage heart failure with preserved ejection fraction in the pig.
J Anat. 2020; 236(3):531-539 Doi: 10.1111/joa.13117 [OPEN ACCESS]
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Niestrawska, JA; Augustin, CM; Plank, G Computational modeling of cardiac growth and remodeling in pressure overloaded hearts-Linking microstructure to organ phenotype.
Acta Biomater. 2020; 106:34-53 Doi: 10.1016/j.actbio.2020.02.010 [OPEN ACCESS]
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Panov, V; Minigalieva, I; Bushueva, T; Fröhlich, E; Meindl, C; Absenger-Novak, M; Shur, V; Shishkina, E; Gurvich, V; Privalova, L; Katsnelson, BA Some Peculiarities in the Dose Dependence of Separate and Combined In Vitro Cardiotoxicity Effects Induced by CdS and PbS Nanoparticles With Special Attention to Hormesis Manifestations.
Dose Response. 2020; 18(1):1559325820914180-1559325820914180 Doi: 10.1177/1559325820914180 [OPEN ACCESS]
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Veith, C; Neghabian, D; Luitel, H; Wilhelm, J; Egemnazarov, B; Muntanjohl, C; Fischer, JH; Dahal, BK; Schermuly, RT; Ghofrani, HA; Grimminger, F; Fink, L; Kwapiszewska, G; Weissmann, N; Sydykov, A FHL-1 is not involved in pressure overload-induced maladaptive right ventricular remodeling and dysfunction.
Basic Res Cardiol. 2020; 115(2):17-17 Doi: 10.1007/s00395-019-0767-5 [OPEN ACCESS]
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Wallner, M; Eaton, DM; Berretta, RM; Liesinger, L; Schittmayer, M; Gindlhuber, J; Wu, J; Jeong, MY; Lin, YH; Borghetti, G; Baker, ST; Zhao, H; Pfleger, J; Blass, S; Rainer, PP; von Lewinski, D; Bugger, H; Mohsin, S; Graier, WF; Zirlik, A; McKinsey, TA; Birner-Gruenberger, R; Wolfson, MR; Houser, SR HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Sci Transl Med. 2020; 12(525): Doi: 10.1126/scitranslmed.aay7205 [OPEN ACCESS]
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2019

Bandleon, S; Strunz, PP; Pickel, S; Tiapko, O; Cellini, A; Miranda-Laferte, E; Eder-Negrin, P FKBP52 regulates TRPC3-dependent Ca2+ signals and the hypertrophic growth of cardiomyocyte cultures.
J Cell Sci. 2019; 132(20): Doi: 10.1242/jcs.231506 [OPEN ACCESS]
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Gollmer, J; Zirlik, A; Bugger, H Established and Emerging Mechanisms of Diabetic Cardiomyopathy.
J Lipid Atheroscler. 2019; 8(1):26-47 Doi: 10.12997/jla.2019.8.1.26 [OPEN ACCESS]
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Gonçalves, IF; Acar, E; Costantino, S; Szabo, PL; Hamza, O; Tretter, EV; Klein, KU; Trojanek, S; Abraham, D; Paneni, F; Hallström, S; Kiss, A; Podesser, BK Epigenetic modulation of tenascin C in the heart: implications on myocardial ischemia, hypertrophy and metabolism.
J Hypertens. 2019; 37(9):1861-1870 Doi: 10.1097/HJH.0000000000002097
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Primessnig, U; Bracic, T; Levijoki, J; Otsomaa, L; Pollesello, P; Falcke, M; Pieske, B; Heinzel, FR Long-term effects of Na+ /Ca2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
Eur J Heart Fail. 2019; 21(12):1543-1552 Doi: 10.1002/ejhf.1619 [OPEN ACCESS]
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Wierich, MC; Schipke, J; Brandenberger, C; Abdellatif, M; Eisenberg, T; Madeo, F; Sedej, S; Mühlfeld, C Cardioprotection by spermidine does not depend on structural characteristics of the myocardial microcirculation in aged mice.
Exp Gerontol. 2019; 119:82-88 Doi: 10.1016/j.exger.2019.01.026
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Zucker, MM; Wujak, L; Gungl, A; Didiasova, M; Kosanovic, D; Petrovic, A; Klepetko, W; Schermuly, RT; Kwapiszewska, G; Schaefer, L; Wygrecka, M LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(6):1604-1616 Doi: 10.1016/j.bbadis.2019.03.012 [OPEN ACCESS]
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2018

Alogna, A; Schwarzl, M; Manninger, M; Hamdani, N; Zirngast, B; Kloth, B; Steendijk, P; Verderber, J; Zweiker, D; Westermann, D; Blankenberg, S; Maechler, H; Tschöpe, C; Linke, WA; Marsche, G; Pieske, BM; Post, H Acute stimulation of the soluble guanylate cyclase does not impact on left ventricular capacitance in normal and hypertrophied porcine hearts in vivo.
Am J Physiol Heart Circ Physiol. 2018; 315(3):H669-H680 Doi: 10.1152/ajpheart.00510.2017 [OPEN ACCESS]
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Borghetti, G; von Lewinski, D; Eaton, DM; Sourij, H; Houser, SR; Wallner, M Diabetic Cardiomyopathy: Current and Future Therapies. Beyond Glycemic Control.
Front Physiol. 2018; 9(11):1514-1514 Doi: 10.3389/fphys.2018.01514 [OPEN ACCESS]
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Diehl, P; Gaul, DS; Sogl, J; Flierl, U; Henstridge, D; Pahla, J; Bugger, H; Emmert, MY; Ruschitzka, F; Bode, C; Lüscher, TF; Moser, M; Matter, CM; Peter, K; Winnik, S The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts.
J Thromb Thrombolysis. 2018; 46(1): 102-112. Doi: 10.1007/s11239-018-1677-3
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Fischer, TH; Eiringhaus, J; Dybkova, N; Saadatmand, A; Pabel, S; Weber, S; Wang, Y; Köhn, M; Tirilomis, T; Ljubojevic, S; Renner, A; Gummert, J; Maier, LS; Hasenfuß, G; El-Armouche, A; Sossalla, S Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure.
Eur J Heart Fail. 2018; 20(12):1673-1685 Doi: 10.1002/ejhf.1297 [OPEN ACCESS]
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Harper, SC; Johnson, J; Borghetti, G; Zhao, H; Wang, T; Wallner, M; Kubo, H; Feldsott, EA; Yang, Y; Joo, Y; Gou, X; Sabri, AK; Gupta, P; Myzithras, M; Khalil, A; Franti, M; Houser, SR GDF11 Decreases Pressure Overload-Induced Hypertrophy, but Can Cause Severe Cachexia and Premature Death.
Circ Res. 2018; 123(11):1220-1231 Doi: 10.1161/CIRCRESAHA.118.312955 [OPEN ACCESS]
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Koentges, C; Pepin, ME; Müsse, C; Pfeil, K; Alvarez, SVV; Hoppe, N; Hoffmann, MM; Odening, KE; Sossalla, S; Zirlik, A; Hein, L; Bode, C; Wende, AR; Bugger, H Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans.
Basic Res Cardiol. 2018; 113(1):8-8 Doi: 10.1007/s00395-017-0666-6 [OPEN ACCESS]
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Manninger, M; Zweiker, D; van Hunnik, A; Alogna, A; Prassl, AJ; Schipke, J; Zeemering, S; Zirngast, B; Schönleitner, P; Schwarzl, M; Herbst, V; Thon-Gutschi, E; Huber, S; Rohrer, U; Ebner, J; Brussee, H; Pieske, BM; Heinzel, FR; Verheule, S; Antoons, G; Lueger, A; Mühlfeld, C; Plank, G; Schotten, U; Post, H; Scherr, D Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.
Heart Rhythm. 2018; 15(9):1328-1336 Doi: 10.1016/j.hrthm.2018.05.016
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Mhatre, KN; Wakula, P; Klein, O; Bisping, E; Völkl, J; Pieske, B; Heinzel, FR Crosstalk between FGF23- and angiotensin II-mediated Ca2+ signaling in pathological cardiac hypertrophy.
Cell Mol Life Sci. 2018; 75(23):4403-4416 Doi: 10.1007/s00018-018-2885-x
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Olschewski, H; Rich, S Are anticoagulants still indicated in pulmonary arterial hypertension?
Pulm Circ. 2018; 8(4):2045894018807681-2045894018807681 Doi: 10.1177/2045894018807681 [OPEN ACCESS]
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Zabini, D; Granton, E; Hu, Y; Miranda, MZ; Weichelt, U; Breuils Bonnet, S; Bonnet, S; Morrell, NW; Connelly, KA; Provencher, S; Ghanim, B; Klepetko, W; Olschewski, A; Kapus, A; Kuebler, WM Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition.
Am J Respir Crit Care Med. 2018; 197(2):244-260 Doi: 10.1164/rccm.201702-0386OC
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2017

Illigens, BM; Casar Berazaluce, A; Poutias, D; Gasser, R; Del Nido, PJ; Friehs, I Vascular Endothelial Growth Factor Prevents Endothelial-to-Mesenchymal Transition in Hypertrophy.
Ann Thorac Surg. 2017; 104(3):932-939 Doi: 10.1016/j.athoracsur.2017.01.112 [OPEN ACCESS]
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Mueller, KM; Hartmann, K; Kaltenecker, D; Vettorazzi, S; Bauer, M; Mauser, L; Amann, S; Jall, S; Fischer, K; Esterbauer, H; Müller, TD; Tschöp, MH; Magnes, C; Haybaeck, J; Scherer, T; Bordag, N; Tuckermann, JP; Moriggl, R Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Diabetes. 2017; 66(2):272-286 Doi: 10.2337/db16-0381 [OPEN ACCESS]
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Schuoler, C; Haider, TJ; Leuenberger, C; Vogel, J; Ostergaard, L; Kwapiszewska, G; Kohler, M; Gassmann, M; Huber, LC; Brock, M Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension.
Basic Res Cardiol. 2017; 112(3): 30-30. Doi: 10.1007/s00395-017-0620-7 [OPEN ACCESS]
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Toib, A; Zhang, C; Borghetti, G; Zhang, X; Wallner, M; Yang, Y; Troupes, CD; Kubo, H; Sharp, TE; Feldsott, E; Berretta, RM; Zalavadia, N; Trappanese, DM; Harper, S; Gross, P; Chen, X; Mohsin, S; Houser, SR Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.
Am J Physiol Heart Circ Physiol. 2017; 313(3):H620-H630 Doi: 10.1152/ajpheart.00167.2017 [OPEN ACCESS]
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Troupes, CD; Wallner, M; Borghetti, G; Zhang, C; Mohsin, S; von Lewinski, D; Berretta, RM; Kubo, H; Chen, X; Soboloff, J; Houser, S Role of STIM1 (Stromal Interaction Molecule 1) in Hypertrophy-Related Contractile Dysfunction.
Circ Res. 2017; 121(2):125-136 Doi: 10.1161/CIRCRESAHA.117.311094 [OPEN ACCESS]
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Verheyen, N; Meinitzer, A; Grübler, MR; Ablasser, K; Kolesnik, E; Fahrleitner-Pammer, A; Belyavskiy, E; Trummer, C; Schwetz, V; Pieske-Kraigher, E; Voelkl, J; Alesutan, I; Catena, C; Sechi, LA; Brussee, H; Lewinski, DV; März, W; Pieske, B; Pilz, S; Tomaschitz, A Low-grade inflammation and tryptophan-kynurenine pathway activation are associated with adverse cardiac remodeling in primary hyperparathyroidism: the EPATH trial.
Clin Chem Lab Med. 2017; 55(7):1034-1042 Doi: 10.1515/cclm-2016-1159
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