Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: HEPATOCELLULAR CARCINOMA (HCC), . Treffer: 73

2020

Cubero, FJ; Mohamed, MR; Woitok, MM; Zhao, G; Hatting, M; Nevzorova, YA; Chen, C; Haybaeck, J; de Bruin, A; Avila, MA; Boekschoten, MV; Davis, RJ; Trautwein, C Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma.
Hepatol Commun. 2020; 4(6): 834-851. [OPEN ACCESS]
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Nardo, AD; Grün, NG; Zeyda, M; Dumanic, M; Oberhuber, G; Rivelles, E; Helbich, TH; Markgraf, DF; Roden, M; Claudel, T; Trauner, M; Stulnig, TM Impact of osteopontin on the development of non-alcoholic liver disease and related hepatocellular carcinoma.
Liver Int. 2020; 40(7):1620-1633
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2019

Denk, H; Stumptner, C; Abuja, PM; Zatloukal, K Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma.
Expert Opin Ther Targets. 2019; 23(5):393-406
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Golob-Schwarzl, N; Bettermann, K; Mehta, AK; Kessler, SM; Unterluggauer, J; Krassnig, S; Kojima, K; Chen, X; Hoshida, Y; Bardeesy, NM; Müller, H; Svendova, V; Schimek, MG; Diwoky, C; Lipfert, A; Mahajan, V; Stumptner, C; Thüringer, A; Fröhlich, LF; Stojakovic, T; Nilsson, KPR; Kolbe, T; Rülicke, T; Magin, TM; Strnad, P; Kiemer, AK; Moriggl, R; Haybaeck, J High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype.
Transl Oncol. 2019; 12(2):256-268 [OPEN ACCESS]
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Kröhler, T; Kessler, SM; Hosseini, K; List, M; Barghash, A; Patial, S; Laggai, S; Gemperlein, K; Haybaeck, J; Müller, R; Helms, V; Schulz, MH; Hoppstädter, J; Blackshear, PJ; Kiemer, AK The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma.
Cancers (Basel). 2019; 11(11): [OPEN ACCESS]
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Lokau, J; Schoeder, V; Haybaeck, J; Garbers, C Jak-Stat Signaling Induced by Interleukin-6 Family Cytokines in Hepatocellular Carcinoma.
Cancers (Basel). 2019; 11(11): [OPEN ACCESS]
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2018

Apostolidis, L; Pfeiffenberger, J; Gotthardt, D; Radeleff, B; Mehrabi, A; Schemmer, P; Jager, D; Schirmacher, P; Stremmel, W; Schulze-Bergkamen, H; Springfeld, C; Weiss, KH Survival of Hepatocellular Carcinoma Patients Treated with Sorafenib beyond Progression
GASTROINTEST TUMORS. 2018; 5(1-2): 38-46. [OPEN ACCESS]
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Filali Bouami, S; Gwiasda, J; Beneke, J; Kaltenborn, A; Liersch, S; Suero, EM; Koch, HF; Krauth, C; Klempnauer, J; Schrem, H Prognostic factors for long-term survival after adult liver transplantation.
Langenbecks Arch Surg. 2018; 403(4): 495-508.
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Heits, N; Brosch, M; Herrmann, A; Behrens, R; Röcken, C; Schrem, H; Kaltenborn, A; Klempnauer, J; Kreipe, HH; Reichert, B; Lenschow, C; Wilms, C; Vogel, T; Wolters, H; Wardelmann, E; Seehofer, D; Buch, S; Zeissig, S; Pannach, S; Raschzok, N; Dietel, M; von Schoenfels, W; Hinz, S; Teufel, A; Evert, M; Franke, A; Becker, T; Braun, F; Hampe, J; Schafmayer, C Evolutionary Distance Predicts Recurrence After Liver Transplantation in Multifocal Hepatocellular Carcinoma.
Transplantation. 2018; 102(10): e424-e430-e424-e430.
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Kozbial, K; Moser, S; Al-Zoairy, R; Schwarzer, R; Datz, C; Stauber, R; Laferl, H; Strasser, M; Beinhardt, S; Stättermayer, AF; Gschwantler, M; Zoller, H; Maieron, A; Graziadei, I; Trauner, M; Steindl-Munda, P; Hofer, H; Ferenci, P Follow-up of sustained virological responders with hepatitis C and advanced liver disease after interferon/ribavirin-free treatment.
Liver Int. 2018; 38(6):1028-1035 [OPEN ACCESS]
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Krstic, J; Galhuber, M; Schulz, TJ; Schupp, M; Prokesch, A p53 as a Dichotomous Regulator of Liver Disease: The Dose Makes the Medicine.
Int J Mol Sci. 2018; 19(3): [OPEN ACCESS]
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Li, M; Su, Y; Zhang, F; Chen, K; Xu, X; Xu, L; Zhou, J; Wang, W A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapy.
Acta Biomater. 2018; 75: 413-426.
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Qu, Z; Ling, Q; Gwiasda, J; Xu, X; Schrem, H; Beneke, J; Kaltenborn, A; Krauth, C; Mix, H; Klempnauer, J; Emmanouilidis, N Hangzhou criteria are more accurate than Milan criteria in predicting long-term survival after liver transplantation for HCC in Germany.
Langenbecks Arch Surg. 2018; 403(5): 643-654.
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2017

Aigelsreiter, A; Neumann, J; Pichler, M; Halasz, J; Zatloukal, K; Berghold, A; Douschan, P; Rainer, F; Stauber, R; Haybaeck, J; Denk, H; Lackner, C Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis.
Liver Int. 2017; 37(4):600-610
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Dengler, M; Staufer, K; Huber, H; Stauber, R; Bantel, H; Weiss, KH; Starlinger, P; Pock, H; Klöters-Plachky, P; Gotthardt, DN; Rauch, P; Lackner, C; Stift, J; Brostjan, C; Gruenberger, T; Kumada, T; Toyoda, H; Tada, T; Weiss, TS; Trauner, M; Mikulits, W Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis.
Oncotarget. 2017; 8(28):46234-46248 [OPEN ACCESS]
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Ganten, TM; Stauber, RE; Schott, E; Malfertheiner, P; Buder, R; Galle, PR; Göhler, T; Walther, M; Koschny, R; Gerken, G Sorafenib in Patients with Hepatocellular Carcinoma-Results of the Observational INSIGHT Study.
Clin Cancer Res. 2017; 23(19):5720-5728 [OPEN ACCESS]
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Golob-Schwarzl, N; Krassnig, S; Toeglhofer, AM; Park, YN; Gogg-Kamerer, M; Vierlinger, K; Schröder, F; Rhee, H; Schicho, R; Fickert, P; Haybaeck, J New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.
Eur J Cancer. 2017; 83(60):56-70
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Görtz, M; Galli, U; Longerich, T; Zöller, M; Erb, U; Schemmer, P De novo synthesis of C4.4A in hepatocellular carcinoma promotes migration and invasion of tumor cells.
Oncol Rep. 2017; 38(5):2697-2704 [OPEN ACCESS]
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Lin, S; Hoffmann, K; Gao, C; Petrulionis, M; Herr, I; Schemmer, P Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma.
J PINEAL RES. 2017; 62(3):
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Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
PLoS One. 2017; 12(11):e0187814-e0187814 [OPEN ACCESS]
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Wimmer, T; Steiner, J; Talakic, E; Stauber, R; Quehenberger, F; Portugaller, RH; Schoellnast, H Computed Tomography Perfusion Following Transarterial Chemoembolization of Hepatocellular Carcinoma: A Feasibility Study in the Early Period.
J Comput Assist Tomogr. 2017; 41(5):708-712
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2016

Emmanouilidis, N; Peters, R; Ringe, BP; Güner, Z; Ramackers, W; Bektas, H; Lehner, F; Manns, M; Klempnauer, J; Schrem, H Liver Transplantation for Hepatocellular Carcinoma: A Single Center Resume Overlooking Four Decades of Experience.
J Transplant. 2016; 2016(5): 7895956-7895956. [OPEN ACCESS]
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Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781 [OPEN ACCESS]
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Trierweiler, C; Hockenjos, B; Zatloukal, K; Thimme, R; Blum, HE; Wagner, EF; Hasselblatt, P The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice.
Cell Death Differ. 2016; 23(4):576-582 [OPEN ACCESS]
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2015

Ehedego, H; Boekschoten, MV; Hu, W; Doler, C; Haybaeck, J; Gaβler, N; Müller, M; Liedtke, C; Trautwein, C p21 ablation in liver enhances DNA damage, cholestasis, and carcinogenesis.
Cancer Res. 2015; 75(6):1144-1155 [OPEN ACCESS]
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Hoffmann, K; Ganten, T; Gotthardtp, D; Radeleff, B; Settmacher, U; Kollmar, O; Nadalin, S; Karapanagiotou-Schenkel, I; von Kalle, C; Jäger, D; Büchler, MW; Schemmer, P Impact of neo-adjuvant Sorafenib treatment on liver transplantation in HCC patients - a prospective, randomized, double-blind, phase III trial.
BMC Cancer. 2015; 15(11):392-392 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Barghash, A; Schultheiss, CS; Lederer, E; Artl, M; Helms, V; Haybaeck, J; Kiemer, AK IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.
Cell Death Dis. 2015; 6(1):e1894-e1894 [OPEN ACCESS]
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Piros, L; Fehérvári, I; Görög, D; Nemes, B; Szabó, J; Gerlei, Z; Végső, G; Kóbori, L; Máthé, Z Examinations of Factors Influencing Survival of Liver Transplantation for Hepatocellular Carcinoma: A Single-Center Experience From Budapest.
Transplant Proc. 2015; 47(7):2201-2206
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Reichl, P; Fang, M; Starlinger, P; Staufer, K; Nenutil, R; Muller, P; Greplova, K; Valik, D; Dooley, S; Brostjan, C; Gruenberger, T; Shen, J; Man, K; Trauner, M; Yu, J; Gao, CF; Mikulits, W Multicenter analysis of soluble Axl reveals diagnostic value for very early stage hepatocellular carcinoma.
Int J Cancer. 2015; 137(2):385-394 [OPEN ACCESS]
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Rutter, K; Stättermayer, AF; Beinhardt, S; Scherzer, TM; Steindl-Munda, P; Trauner, M; Ferenci, P; Hofer, H Successful anti-viral treatment improves survival of patients with advanced liver disease due to chronic hepatitis C.
Aliment Pharmacol Ther. 2015; 41(6):521-531 [OPEN ACCESS]
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Stotz, M; Gerger, A; Haybaeck, J; Kiesslich, T; Bullock, MD; Pichler, M Molecular Targeted Therapies in Hepatocellular Carcinoma: Past, Present and Future.
Anticancer Res. 2015; 35(11):5737-5744
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2014

Bruns, H; Petrulionis, M; Schultze, D; Al Saeedi, M; Lin, S; Yamanaka, K; Ambrazevičius, M; Strupas, K; Schemmer, P Glycine inhibits angiogenic signaling in human hepatocellular carcinoma cells.
Amino Acids. 2014; 46(4):969-976
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Flecken, T; Schmidt, N; Hild, S; Gostick, E; Drognitz, O; Zeiser, R; Schemmer, P; Bruns, H; Eiermann, T; Price, DA; Blum, HE; Neumann-Haefelin, C; Thimme, R Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma.
Hepatology. 2014; 59(4):1415-1426 [OPEN ACCESS]
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Friedrich, K; Wannhoff, A; Kattner, S; Brune, M; Hov, JR; Weiss, KH; Antoni, C; Dollinger, M; Neumann-Haefelin, C; Seufferlein, T; Schemmer, P; Schirmacher, P; Stremmel, W; Gotthardt, DN PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.
J Gastroenterol Hepatol. 2014; 29(7):1477-1484
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García-Rodríguez, JL; Barbier-Torres, L; Fernández-Álvarez, S; Gutiérrez-de Juan, V; Monte, MJ; Halilbasic, E; Herranz, D; Álvarez, L; Aspichueta, P; Marín, JJ; Trauner, M; Mato, JM; Serrano, M; Beraza, N; Martínez-Chantar, ML SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
Hepatology. 2014; 59(5):1972-1983 [OPEN ACCESS]
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12):2393-2403 [OPEN ACCESS]
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Hucke, F; Pinter, M; Graziadei, I; Bota, S; Vogel, W; Müller, C; Heinzl, H; Waneck, F; Trauner, M; Peck-Radosavljevic, M; Sieghart, W How to STATE suitability and START transarterial chemoembolization in patients with intermediate stage hepatocellular carcinoma.
J Hepatol. 2014; 61(6):1287-1296
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Hucke, F; Sieghart, W; Pinter, M; Graziadei, I; Vogel, W; Müller, C; Heinzl, H; Waneck, F; Trauner, M; Peck-Radosavljevic, M The ART-strategy: sequential assessment of the ART score predicts outcome of patients with hepatocellular carcinoma re-treated with TACE.
J Hepatol. 2014; 60(1):118-126
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Kessler, SM; Simon, Y; Gemperlein, K; Gianmoena, K; Cadenas, C; Zimmer, V; Pokorny, J; Barghash, A; Helms, V; van Rooijen, N; Bohle, RM; Lammert, F; Hengstler, JG; Mueller, R; Haybaeck, J; Kiemer, AK Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.
Int J Mol Sci. 2014; 15(4):5762-5773 [OPEN ACCESS]
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Lanaya, H; Natarajan, A; Komposch, K; Li, L; Amberg, N; Chen, L; Wculek, SK; Hammer, M; Zenz, R; Peck-Radosavljevic, M; Sieghart, W; Trauner, M; Wang, H; Sibilia, M EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation.
Nat Cell Biol. 2014; 16(10): 1- 7. [OPEN ACCESS]
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Pinter, M; Hucke, F; Zielonke, N; Trauner, M; Sieghart, W; Peck-Radosavljevic, M Epidemiological trends of hepatocellular carcinoma in Austria.
Dig Dis. 2014; 32(6):664-669
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Stampfl, U; Bermejo, JL; Sommer, CM; Hoffmann, K; Weiss, KH; Schirmacher, P; Schemmer, P; Kauczor, HU; Richter, GM; Radeleff, BA; Longerich, T Efficacy and nontarget effects of transarterial chemoembolization in bridging of hepatocellular carcinoma patients to liver transplantation: a histopathologic study.
J Vasc Interv Radiol. 2014; 25(7):1018-1026
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Welte, S; Urbanik, T; Elßner, C; Kautz, N; Koehler, BC; Waldburger, N; Bermejo, JL; Pinna, F; Weiss, KH; Schemmer, P; Jaeger, D; Longerich, T; Breuhahn, K; Schulze-Bergkamen, H Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma.
PLoS One. 2014; 9(10):e110591-e110591 [OPEN ACCESS]
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2013

Aigelsreiter, A; Ress, AL; Bettermann, K; Schauer, S; Koller, K; Eisner, F; Kiesslich, T; Stojakovic, T; Samonigg, H; Kornprat, P; Lackner, C; Haybaeck, J; Pichler, M Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma.
Br J Cancer. 2013; 108(9):1830-1837 [OPEN ACCESS]
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Koschny, R; Brost, S; Hinz, U; Sykora, J; Batke, EM; Singer, S; Breuhahn, K; Stremmel, W; Walczak, H; Schemmer, P; Schirmacher, P; Ganten, TM Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma.
BMC Cancer. 2013; 13(5):532-532 [OPEN ACCESS]
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Lin, S; Hoffmann, K; Xiao, Z; Jin, N; Galli, U; Mohr, E; Büchler, MW; Schemmer, P MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma.
Cancer Cell Int. 2013; 13(1):3-3 [OPEN ACCESS]
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Pfeiffenberger, J; Koschny, R; Hoffmann, K; Mehrabi, A; Schmitz, A; Radeleff, B; Stremmel, W; Schemmer, P; Ganten, TM Sorafenib treatment is save and may affect survival of recurrent hepatocellular carcinoma after liver transplantation.
Langenbecks Arch Surg. 2013; 398(8):1123-1128
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Pinter, M; Sieghart, W; Schmid, M; Dauser, B; Prager, G; Dienes, HP; Trauner, M; Peck-Radosavljevic, M Hedgehog inhibition reduces angiogenesis by downregulation of tumoral VEGF-A expression in hepatocellular carcinoma.
United European Gastroenterol J. 2013; 1(4):265-275 [OPEN ACCESS]
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Yamanaka, K; Petrulionis, M; Lin, S; Gao, C; Galli, U; Richter, S; Winkler, S; Houben, P; Schultze, D; Hatano, E; Schemmer, P Therapeutic potential and adverse events of everolimus for treatment of hepatocellular carcinoma - systematic review and meta-analysis.
Cancer Med. 2013; 2(6):862-871 [OPEN ACCESS]
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2012

Heuer, M; Kaiser, GM; Kahraman, A; Banysch, M; Saner, FH; Mathé, Z; Gerken, G; Paul, A; Canbay, A; Treckmann, JW Liver transplantation in nonalcoholic steatohepatitis is associated with high mortality and post-transplant complications: a single-center experience.
Digestion. 2012; 86(2):107-113
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