Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: FATTY LIVER, . Treffer: 111

2020

Craciun, A; Lackner, C; Cortez-Pinto, H Nonalcoholic Fatty Liver Disease versus Alcohol-related Liver Disease: Is it Really so Different?
CURR PHARM DESIGN. 2020; 26(10): 1093-1109.
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Mörwald, K; Aigner, E; Bergsten, P; Brunner, SM; Forslund, A; Kullberg, J; Ahlström, H; Manell, H; Roomp, K; Schütz, S; Zsoldos, F; Renner, W; Furthner, D; Maruszczak, K; Zandanell, S; Weghuber, D; Mangge, H Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity.
Front Endocrinol (Lausanne). 2020; 11: 340-340. [OPEN ACCESS]
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Nardo, AD; Grün, NG; Zeyda, M; Dumanic, M; Oberhuber, G; Rivelles, E; Helbich, TH; Markgraf, DF; Roden, M; Claudel, T; Trauner, M; Stulnig, TM Impact of osteopontin on the development of non-alcoholic liver disease and related hepatocellular carcinoma.
Liver Int. 2020; 40(7):1620-1633 [OPEN ACCESS]
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Safari, Z; Bruneau, A; Monnoye, M; Mariadassou, M; Philippe, C; Zatloukal, K; Gerard, P Murine Genetic Background Overcomes Gut Microbiota Changes to Explain Metabolic Response to High-Fat Diet
NUTRIENTS. 2020; 12(2): 287 [OPEN ACCESS]
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2019

Denk, H; Abuja, PM; Zatloukal, K Animal models of NAFLD from the pathologist's point of view.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(5):929-942
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Grabner, GF; Fawzy, N; Pribasnig, MA; Trieb, M; Taschler, U; Holzer, M; Schweiger, M; Wolinski, H; Kolb, D; Horvath, A; Breinbauer, R; Rülicke, T; Rabl, R; Lass, A; Stadlbauer, V; Hutter-Paier, B; Stauber, RE; Fickert, P; Zechner, R; Marsche, G; Eichmann, TO; Zimmermann, R Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans.
J Lipid Res. 2019; 60(5):1020-1031 [OPEN ACCESS]
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Kaltenecker, D; Themanns, M; Mueller, KM; Spirk, K; Golob-Schwarzl, N; Friedbichler, K; Kenner, L; Haybaeck, J; Moriggl, R STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.
Cytokine. 2018; 154573-154573 [OPEN ACCESS]
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Kaltenecker, D; Themanns, M; Mueller, KM; Spirk, K; Suske, T; Merkel, O; Kenner, L; Luís, A; Kozlov, A; Haybaeck, J; Müller, M; Han, X; Moriggl, R Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression.
Cytokine. 2018; 154569-154569 [OPEN ACCESS]
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Lackner, C; Tiniakos, D Fibrosis and alcohol-related liver disease.
J HEPATOL. 2019; 70(2): 294-304.
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Maresch, LK; Benedikt, P; Feiler, U; Eder, S; Zierler, KA; Taschler, U; Kolleritsch, S; Eichmann, TO; Schoiswohl, G; Leopold, C; Wieser, BI; Lackner, C; Rülicke, T; van Klinken, J; Kratky, D; Moustafa, T; Hoefler, G; Haemmerle, G Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
Hepatol Commun. 2019; 3(2): 227-245. [OPEN ACCESS]
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Safari, Z; Gérard, P The links between the gut microbiome and non-alcoholic fatty liver disease (NAFLD).
Cell Mol Life Sci. 2019; 76(8):1541-1558
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Safari, Z; Monnoye, M; Abuja, PM; Mariadassou, M; Kashofer, K; Gérard, P; Zatloukal, K Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration.
Nutr Res. 2019; 71: 72-88.
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Staufer, K; Halilbasic, E; Spindelboeck, W; Eilenberg, M; Prager, G; Stadlbauer, V; Posch, A; Munda, P; Marculescu, R; Obermayer-Pietsch, B; Stift, J; Lackner, C; Trauner, M; Stauber, RE Evaluation and comparison of six noninvasive tests for prediction of significant or advanced fibrosis in nonalcoholic fatty liver disease
UNITED EUR GASTROENT. 2019; UNSP 2050640619865133 [OPEN ACCESS]
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Tapking, C; Houschyar, KS; Rontoyanni, VG; Hundeshagen, G; Kowalewski, KF; Hirche, C; Popp, D; Wolf, SE; Herndon, DN; Branski, LK The Influence of Obesity on Treatment and Outcome of Severely Burned Patients.
J Burn Care Res. 2019; 40(6):996-1008 [OPEN ACCESS]
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Tardelli, M; Bruschi, FV; Claudel, T; Fuchs, CD; Auer, N; Kunczer, V; Stojakovic, T; Scharnagl, H; Habib, A; Grabner, GF; Zimmermann, R; Lotersztajn, S; Trauner, M Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption.
J Lipid Res. 2019; 60(7): 1284-1292. [OPEN ACCESS]
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Traussnigg, S; Schattenberg, JM; Demir, M; Wiegand, J; Geier, A; Teuber, G; Hofmann, WP; Kremer, AE; Spreda, F; Kluwe, J; Petersen, J; Boettler, T; Rainer, F; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Fickert, P; Trauner, M; Austrian/German NAFLD-norUDCA study group Norursodeoxycholic acid versus placebo in the treatment of non-alcoholic fatty liver disease: a double-blind, randomised, placebo-controlled, phase 2 dose-finding trial.
LANCET GASTROENTEROL. 2019; 4(10): 781-793.
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2018

Argo, CK; Stine, JG; Henry, ZH; Lackner, C; Patrie, JT; Weltman, AL; Caldwell, SH Physical deconditioning is the common denominator in both obese and overweight subjects with nonalcoholic steatohepatitis.
Aliment Pharmacol Ther. 2018; 48(3): 290-299. [OPEN ACCESS]
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Denkmayr, L; Feldman, A; Stechemesser, L; Eder, SK; Zandanell, S; Schranz, M; Strasser, M; Huber-Schönauer, U; Buch, S; Hampe, J; Paulweber, B; Lackner, C; Haufe, H; Sotlar, K; Datz, C; Aigner, E Lean Patients with Non-Alcoholic Fatty Liver Disease Have a Severe Histological Phenotype Similar to Obese Patients.
J Clin Med. 2018; 7(12): [OPEN ACCESS]
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Graffmann, N; Bohndorf, M; Ncube, A; Kawala, MA; Wruck, W; Kashofer, K; Zatloukal, K; Adjaye, J Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30-40% steatosis) with homozygous wildtype PNPLA3 genotype.
Stem Cell Res. 2018; 31: 113-116. [OPEN ACCESS]
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Graffmann, N; Bohndorf, M; Ncube, A; Wruck, W; Kashofer, K; Zatloukal, K; Adjaye, J Establishment and characterization of an iPSC line from a 58 years old high grade patient with nonalcoholic fatty liver disease (70% steatosis) with homozygous wildtype PNPLA3 genotype.
Stem Cell Res. 2018; 31(4):131-134 (- Case Report) [OPEN ACCESS]
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Krstic, J; Galhuber, M; Schulz, TJ; Schupp, M; Prokesch, A p53 as a Dichotomous Regulator of Liver Disease: The Dose Makes the Medicine.
Int J Mol Sci. 2018; 19(3): [OPEN ACCESS]
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Seitz, HK; Bataller, R; Cortez-Pinto, H; Gao, B; Gual, A; Lackner, C; Mathurin, P; Mueller, S; Szabo, G; Tsukamoto, H Alcoholic liver disease.
Nat Rev Dis Primers. 2018; 4(1):16-16
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Vahdati Hassani, F; Abnous, K; Mehri, S; Jafarian, A; Birner-Gruenberger, R; Yazdian Robati, R; Hosseinzadeh, H Proteomics and phosphoproteomics analysis of liver in male rats exposed to bisphenol A: Mechanism of hepatotoxicity and biomarker discovery.
Food Chem Toxicol. 2018; 112(3):26-38
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2017

Caldwell, S; Lackner, C Perspectives on NASH Histology: Cellular Ballooning.
ANN HEPATOL. 2017; 16(2): 182-184. [OPEN ACCESS]
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Dengler, M; Staufer, K; Huber, H; Stauber, R; Bantel, H; Weiss, KH; Starlinger, P; Pock, H; Klöters-Plachky, P; Gotthardt, DN; Rauch, P; Lackner, C; Stift, J; Brostjan, C; Gruenberger, T; Kumada, T; Toyoda, H; Tada, T; Weiss, TS; Trauner, M; Mikulits, W Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis.
Oncotarget. 2017; 8(28):46234-46248 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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Lindquist, C; Bjørndal, B; Rossmann, CR; Tusubira, D; Svardal, A; Røsland, GV; Tronstad, KJ; Hallström, S; Berge, RK Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats.
J Lipid Res. 2017; 58(7):1362-1373 [OPEN ACCESS]
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Mueller, S; Nahon, P; Rausch, V; Peccerella, T; Silva, I; Yagmur, E; Straub, BK; Lackner, C; Seitz, HK; Rufat, P; Sutton, A; Bantel, H; Longerich, T Caspase-cleaved keratin-18 fragments increase during alcohol withdrawal and predict liver-related death in patients with alcoholic liver disease.
Hepatology. 2017; 66(1):96-107
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Schweiger, M; Romauch, M; Schreiber, R; Grabner, GF; Hütter, S; Kotzbeck, P; Benedikt, P; Eichmann, TO; Yamada, S; Knittelfelder, O; Diwoky, C; Doler, C; Mayer, N; De Cecco, W; Breinbauer, R; Zimmermann, R; Zechner, R Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Nat Commun. 2017; 8(5):14859-14859 [OPEN ACCESS]
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Zöhrer, E; Alisi, A; Jahnel, J; Mosca, A; Della Corte, C; Crudele, A; Fauler, G; Nobili, V Efficacy of docosahexaenoic acid-choline-vitamin E in paediatric NASH: a randomized controlled clinical trial.
Appl Physiol Nutr Metab. 2017; 42(9):948-954
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2016

Fengler, VH; Macheiner, T; Kessler, SM; Czepukojc, B; Gemperlein, K; Müller, R; Kiemer, AK; Magnes, C; Haybaeck, J; Lackner, C; Sargsyan, K Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.
PLoS One. 2016; 11(5):e0155163-e0155163 [OPEN ACCESS]
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Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity.
Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Van Wonterg, E; Gemperlein, K; Müller, R; Haybaeck, J; Vandenbroucke, RE; Ogris, M; Libert, C; Kiemer, AK Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.
Front Physiol. 2016; 7(9):147-147 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Van Wonterghem, E; Gemperlein, K; Müller, R; Haybaeck, J; Vandenbroucke, RE; Ogris, M; Libert, C; Kiemer, AK Corrigendum: Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.
Front Physiol. 2016; 7: 328-328. [OPEN ACCESS]
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Munteanu, M; Tiniakos, D; Anstee, Q; Charlotte, F; Marchesini, G; Bugianesi, E; Trauner, M; Romero Gomez, M; Oliveira, C; Day, C; Dufour, JF; Bellentani, S; Ngo, Y; Traussnig, S; Perazzo, H; Deckmyn, O; Bedossa, P; Ratziu, V; Poynard, T; FLIP Consortium and the FibroFrance Group Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.
Aliment Pharmacol Ther. 2016; 44(8):877-889 [OPEN ACCESS]
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Nawata, A; Noguchi, H; Mazaki, Y; Kurahashi, T; Izumi, H; Wang, KY; Guo, X; Uramoto, H; Kohno, K; Taniguchi, H; Tanaka, Y; Fujii, J; Sasaguri, Y; Tanimoto, A; Nakayama, T; Yamada, S Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.
PLoS One. 2016; 11(4):e0152549-e0152549 [OPEN ACCESS]
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Rief, P; Pichler, M; Raggam, R; Hafner, F; Gerger, A; Eller, P; Brodmann, M; Gary, T The AST/ALT (De-Ritis) ratio: A novel marker for critical limb ischemia in peripheral arterial occlusive disease patients.
Medicine (Baltimore). 2016; 95(24):e3843-e3843 [OPEN ACCESS]
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Themanns, M; Mueller, KM; Kessler, SM; Golob-Schwarzl, N; Mohr, T; Kaltenecker, D; Bourgeais, J; Paier-Pourani, J; Friedbichler, K; Schneller, D; Schlederer, M; Zebedin-Brandl, E; Terracciano, LM; Han, X; Kenner, L; Wagner, KU; Mikulits, W; Kozlov, AV; Heim, MH; Gouilleux, F; Haybaeck, J; Moriggl, R Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
Sci Rep. 2016; 6(4):34719-34719 [OPEN ACCESS]
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2015

Argo, CK; Patrie, JT; Lackner, C; Henry, TD; de Lange, EE; Weltman, AL; Shah, NL; Al-Osaimi, AM; Pramoonjago, P; Jayakumar, S; Binder, LP; Simmons-Egolf, WD; Burks, SG; Bao, Y; Taylor, AG; Rodriguez, J; Caldwell, SH Effects of n-3 fish oil on metabolic and histological parameters in NASH: a double-blind, randomized, placebo-controlled trial.
J Hepatol. 2015; 62(1):190-197 [OPEN ACCESS]
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Beilfuss, A; Sowa, JP; Sydor, S; Beste, M; Bechmann, LP; Schlattjan, M; Syn, WK; Wedemeyer, I; Mathé, Z; Jochum, C; Gerken, G; Gieseler, RK; Canbay, A Vitamin D counteracts fibrogenic TGF-β signalling in human hepatic stellate cells both receptor-dependently and independently.
Gut. 2015; 64(5):791-799
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Bitter, A; Rümmele, P; Klein, K; Kandel, BA; Rieger, JK; Nüssler, AK; Zanger, UM; Trauner, M; Schwab, M; Burk, O Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms.
Arch Toxicol. 2015; 89(11):2089-2103
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Burt, AD; Lackner, C; Tiniakos, DG Diagnosis and Assessment of NAFLD: Definitions and Histopathological Classification.
Semin Liver Dis. 2015; 35(3):207-220 [OPEN ACCESS]
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Jahnel, J; Zöhrer, E; Alisi, A; Ferrari, F; Ceccarelli, S; De Vito, R; Scharnagl, H; Stojakovic, T; Fauler, G; Trauner, M; Nobili, V Serum Bile Acid Levels in Children With Nonalcoholic Fatty Liver Disease.
J Pediatr Gastroenterol Nutr. 2015; 61(1):85-90
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Mangge, H; Baumgartner, BG; Zelzer, S; Prüller, F; Schnedl, WJ; Reininghaus, EZ; Haybaeck, J; Lackner, C; Stauber, R; Aigner, E; Weghuber, D Patatin-like phospholipase 3 (rs738409) gene polymorphism is associated with increased liver enzymes in obese adolescents and metabolic syndrome in all ages.
Aliment Pharmacol Ther. 2015; 42(1):99-105 [OPEN ACCESS]
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Mueller, M; Thorell, A; Claudel, T; Jha, P; Koefeler, H; Lackner, C; Hoesel, B; Fauler, G; Stojakovic, T; Einarsson, C; Marschall, HU; Trauner, M Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity.
J Hepatol. 2015; 62(6):1398-1404 [OPEN ACCESS]
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Nobili, V; Vajro, P; Dezsofi, A; Fischler, B; Hadzic, N; Jahnel, J; Lamireau, T; McKiernan, P; McLin, V; Socha, P; Tizzard, S; Baumann, U Indications and limitations of bariatric intervention in severely obese children and adolescents with and without nonalcoholic steatohepatitis: ESPGHAN Hepatology Committee Position Statement.
J Pediatr Gastroenterol Nutr. 2015; 60(4):550-561
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Stättermayer, AF; Traussnigg, S; Dienes, HP; Aigner, E; Stauber, R; Lackner, K; Hofer, H; Stift, J; Wrba, F; Stadlmayr, A; Datz, C; Strasser, M; Maieron, A; Trauner, M; Ferenci, P Hepatic steatosis in Wilson disease--Role of copper and PNPLA3 mutations.
J Hepatol. 2015; 63(1):156-163
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Trauner, M; Halilbasic, E; Claudel, T; Steinacher, D; Fuchs, C; Moustafa, T; Pollheimer, M; Krones, E; Kienbacher, C; Traussnigg, S; Kazemi-Shirazi, L; Munda, P; Hofer, H; Fickert, P; Paumgartner, G Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.
Dig Dis. 2015; 33(3):433-439
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Wruck, W; Kashofer, K; Rehman, S; Daskalaki, A; Berg, D; Gralka, E; Jozefczuk, J; Drews, K; Pandey, V; Regenbrecht, C; Wierling, C; Turano, P; Korf, U; Zatloukal, K; Lehrach, H; Westerhoff, HV; Adjaye, J Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes.
Sci Data. 2015; 2(S 01):150068-150068 [OPEN ACCESS]
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2014

Bastati, N; Feier, D; Wibmer, A; Traussnigg, S; Balassy, C; Tamandl, D; Einspieler, H; Wrba, F; Trauner, M; Herold, C; Ba-Ssalamah, A Noninvasive differentiation of simple steatosis and steatohepatitis by using gadoxetic acid-enhanced MR imaging in patients with nonalcoholic fatty liver disease: a proof-of-concept study.
Radiology. 2014; 271(3): 739-747. [OPEN ACCESS]
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