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Publikationen

Suchbegriffe: EOSINOPHILS, . Treffer: 99

2023

Krysko, O; Korsakova, D; Teufelberger, A; De, Meyer, A; Steels, J; De, Ruyck, N; van, Ovost, J; Van, Nevel, S; Holtappels, G; Coppieters, F; Ivanchenko, M; Braun, H; Vedunova, M; Krysko, DV; Bachert, C Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice.
Front Immunol. 2023; 14: 1040493 Doi: 10.3389/fimmu.2023.1040493 [OPEN ACCESS]
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LeSuer, WE; Kienzl, M; Ochkur, SI; Schicho, R; Doyle, AD; Wright, BL; Rank, MA; Krupnick, AS; Kita, H; Jacobsen, EA Eosinophils promote effector functions of lung ILC2s in allergic airway inflammation in mice.
J Allergy Clin Immunol. 2023; Doi: 10.1016/j.jaci.2023.03.023
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2022

Kolland, M; Ribitsch, W; Prenner, A; Buchgraber, J; Odler, B; Krause, R; Rosenkranz, AR Effluent microscopy is a useful adjuvant diagnostic tool in peritoneal dialysis-associated peritonitis.
Clin Nephrol. 2022; 98(1):33-41 Doi: 10.5414/CN110732
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Schnoegl, D; Hochgerner, M; Gotthardt, D; Marsh, LM Fra-2 Is a Dominant Negative Regulator of Natural Killer Cell Development.
FRONT IMMUNOL. 2022; 13: 909270 Doi: 10.3389/fimmu.2022.909270 [OPEN ACCESS]
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2021

Kienzl, M; Hasenoehrl, C; Maitz, K; Sarsembayeva, A; Taschler, U; Valadez-Cosmes, P; Kindler, O; Ristic, D; Raftopoulou, S; Santiso, A; Bärnthaler, T; Brcic, L; Hahnefeld, L; Gurke, R; Thomas, D; Geisslinger, G; Kargl, J; Schicho, R Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer.
Oncoimmunology. 2021; 10(1): 1965319 Doi: 10.1080/2162402X.2021.1965319 [OPEN ACCESS]
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Knuplez, E; Kienzl, M; Trakaki, A; Schicho, R; Heinemann, A; Sturm, EM; Marsche, G The anti-parasitic drug miltefosine suppresses human eosinophil activation and ameliorates murine allergic inflammation in vivo.
Br J Pharmacol. 2021; 178(5):1234-1248 Doi: 10.1111/bph.15368 [OPEN ACCESS]
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Knuplez, E; Sturm, EM; Marsche, G Emerging Role of Phospholipase-Derived Cleavage Products in Regulating Eosinophil Activity: Focus on Lysophospholipids, Polyunsaturated Fatty Acids and Eicosanoids.
Int J Mol Sci. 2021; 22(9): Doi: 10.3390/ijms22094356 [OPEN ACCESS]
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Luschnig, P; Kienzl, M; Roula, D; Pilic, J; Atallah, R; Heinemann, A; Sturm, EM The JAK1/2 inhibitor baricitinib suppresses eosinophil effector function and restricts allergen-induced airway eosinophilia.
Biochem Pharmacol. 2021; 192: 114690 Doi: 10.1016/j.bcp.2021.114690
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Sturm, EM; Knuplez, E; Marsche, G Role of Short Chain Fatty Acids and Apolipoproteins in the Regulation of Eosinophilia-Associated Diseases.
Int J Mol Sci. 2021; 22(9): Doi: 10.3390/ijms22094377 [OPEN ACCESS]
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Trakaki, A; Marsche, G Current Understanding of the Immunomodulatory Activities of High-Density Lipoproteins.
Biomedicines. 2021; 9(6): Doi: 10.3390/biomedicines9060587 [OPEN ACCESS]
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2020

Kastnerova, L; Belousova, IE; Hadravsky, L; Kerl, H; Cerroni, L; Kerl, K; Boudova, L; Jindra, P; Cerna, K; Michal, M; Kazakov, DV Mummified Cells are a Common Finding in Cutaneous Hodgkin Lymphoma and Can Be Used as a Diagnostic Clue.
Am J Dermatopathol. 2020; 42(1): 24-28. Doi: 10.1097/DAD.0000000000001445
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Kienzl, M; Hasenoehrl, C; Valadez-Cosmes, P; Maitz, K; Sarsembayeva, A; Sturm, E; Heinemann, A; Kargl, J; Schicho, R IL-33 reduces tumor growth in models of colorectal cancer with the help of eosinophils.
ONCOIMMUNOLOGY. 2020; 9(1): 1776059 Doi: 10.1080/2162402X.2020.1776059 [OPEN ACCESS]
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Kluin-Nelemans, HC; Reiter, A; Illerhaus, A; van Anrooij, B; Hartmann, K; Span, LFR; Gorska, A; Niedoszytko, M; Lange, M; Scaffidi, L; Zanotti, R; Bonadonna, P; Perkins, C; Elena, C; Malcovati, L; Shoumariyeh, K; von Bubnoff, N; Parente, R; Triggiani, M; Schwaab, J; Jawhar, M; Caroppo, F; Fortina, AB; Brockow, K; Zink, A; Fuchs, D; Kilbertus, A; Yavuz, AS; Doubek, M; Mattsson, M; Hagglund, H; Panse, J; Sabato, V; Aberer, E; Niederwieser, D; Breynaert, C; Várkonyi, J; Kennedy, V; Lortholary, O; Jakob, T; Hermine, O; Rossignol, J; Arock, M; Gotlib, J; Valent, P; Sperr, WR Prognostic impact of eosinophils in mastocytosis: analysis of 2350 patients collected in the ECNM Registry.
Leukemia. 2020; 34(4):1090-1101 Doi: 10.1038/s41375-019-0632-4 [OPEN ACCESS]
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Knuplez, E; Curcic, S; Theiler, A; Bärnthaler, T; Trakaki, A; Trieb, M; Holzer, M; Heinemann, A; Zimmermann, R; Sturm, EM; Marsche, G Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(7):158686-158686 Doi: 10.1016/j.bbalip.2020.158686 [OPEN ACCESS]
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Knuplez, E; Krier-Burris, R; Cao, Y; Marsche, G; O'Sullivan, J; Bochner, BS Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.
J Leukoc Biol. 2020; 108(1):43-58 Doi: 10.1002/JLB.3HI0120-381R [OPEN ACCESS]
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Roula, D; Theiler, A; Luschnig, P; Sturm, GJ; Tomazic, PV; Marsche, G; Heinemann, A; Sturm, EM Apolipoprotein A-IV acts as an endogenous anti-inflammatory protein and is reduced in treatment-naïve allergic patients and allergen-challenged mice.
Allergy. 2020; 75(2):392-402 Doi: 10.1111/all.14022 [OPEN ACCESS]
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2019

Durchschein, F; Eherer, A; Grill, M; Sturm, EM; Pommer, V; Langner, C; Högenauer, C; Schicho, R Involvement of EP2 and EP4 Receptors in Eosinophilic Esophagitis: A Pilot Study.
Dig Dis Sci. 2019; 64(10):2806-2814 Doi: 10.1007/s10620-019-05623-5 [OPEN ACCESS]
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Jevnikar, Z; Östling, J; Ax, E; Calvén, J; Thörn, K; Israelsson, E; Öberg, L; Singhania, A; Lau, LCK; Wilson, SJ; Ward, JA; Chauhan, A; Sousa, AR; De, Meulder, B; Loza, MJ; Baribaud, F; Sterk, PJ; Chung, KF; Sun, K; Guo, Y; Adcock, IM; Payne, D; Dahlen, B; Chanez, P; Shaw, DE; Krug, N; Hohlfeld, JM; Sandström, T; Djukanovic, R; James, A; Hinks, TSC; Howarth, PH; Vaarala, O; van, Geest, M; Olsson, H, , Unbiased, Biomarkers, in, Prediction, of, Respiratory, Disease, Outcomes, study, group Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.
J Allergy Clin Immunol. 2019; 143(2):577-590 Doi: 10.1016/j.jaci.2018.05.026
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Nycholat, CM; Duan, S; Knuplez, E; Worth, C; Elich, M; Yao, A; O'Sullivan, J; McBride, R; Wei, Y; Fernandes, SM; Zhu, Z; Schnaar, RL; Bochner, BS; Paulson, JC A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and -F on Immune Cells.
J Am Chem Soc. 2019; 141(36):14032-14037 Doi: 10.1021/jacs.9b05769 [OPEN ACCESS]
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Theiler, A; Bärnthaler, T; Platzer, W; Richtig, G; Peinhaupt, M; Rittchen, S; Kargl, J; Ulven, T; Marsh, LM; Marsche, G; Schuligoi, R; Sturm, EM; Heinemann, A Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.
J Allergy Clin Immunol. 2019; 144(3):764-776 Doi: 10.1016/j.jaci.2019.05.002 [OPEN ACCESS]
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Trakaki, A; Sturm, GJ; Pregartner, G; Scharnagl, H; Eichmann, TO; Trieb, M; Knuplez, E; Holzer, M; Stadler, JT; Heinemann, A; Sturm, EM; Marsche, G Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1280-1292 Doi: 10.1016/j.bbalip.2019.06.007 [OPEN ACCESS]
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2018

Gungl, A; Biasin, V; Wilhelm, J; Olschewski, A; Kwapiszewska, G; Marsh, LM Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner.
Front Immunol. 2018; 9(10):2018-2018 Doi: 10.3389/fimmu.2018.02018 [OPEN ACCESS]
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Hekking, PP; Loza, MJ; Pavlidis, S; de, Meulder, B; Lefaudeux, D; Baribaud, F; Auffray, C; Wagener, AH; Brinkman, P; Lutter, R; Bansal, AT; Sousa, AR; Bates, SA; Pandis, Y; Fleming, LJ; Shaw, DE; Fowler, SJ; Guo, Y; Meiser, A; Sun, K; Corfield, J; Howarth, PH; Bel, EH; Adcock, IM; Chung, KF; Djukanovic, R; Sterk, PJ, , U-BIOPRED, Study, Group, , U-BIOPRED, Study, Group Pathway discovery using transcriptomic profiles in adult-onset severe asthma.
J Allergy Clin Immunol. 2018; 141(4):1280-1290 Doi: 10.1016/j.jaci.2017.06.037
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Peinhaupt, M; Roula, D; Theiler, A; Sedej, M; Schicho, R; Marsche, G; Sturm, EM; Sabroe, I; Rothenberg, ME; Heinemann, A DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator.
J Leukoc Biol. 2018; 104(1):159-171 Doi: 10.1002/JLB.3MA1017-404R [OPEN ACCESS]
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Teufelberger, AR; Nordengrün, M; Braun, H; Maes, T; De Grove, K; Holtappels, G; O'Brien, C; Provoost, S; Hammad, H; Gonçalves, A; Beyaert, R; Declercq, W; Vandenabeele, P; Krysko, DV; Bröker, BM; Bachert, C; Krysko, O The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.
J Allergy Clin Immunol. 2018; 141(2): 549-559. Doi: 10.1016/j.jaci.2017.05.004
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2017

Peinhaupt, M; Sturm, EM; Heinemann, A Prostaglandins and Their Receptors in Eosinophil Function and As Therapeutic Targets.
Front Med (Lausanne). 2017; 4(1):104-104 Doi: 10.3389/fmed.2017.00104 [OPEN ACCESS]
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Thiel, J; Troilo, A; Salzer, U; Schleyer, T; Halmschlag, K; Rizzi, M; Frede, N; Venhoff, A; Voll, RE; Venhoff, N Rituximab as Induction Therapy in Eosinophilic Granulomatosis with Polyangiitis Refractory to Conventional Immunosuppressive Treatment: A 36-Month Follow-Up Analysis.
J ALLER CL IMM-PRACT. 2017; 5(6): 1556-1563. Doi: 10.1016/j.jaip.2017.07.027
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2016

Frei, RB; Luschnig, P; Parzmair, GP; Peinhaupt, M; Schranz, S; Fauland, A; Wheelock, CE; Heinemann, A; Sturm, EM Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice.
Allergy. 2016; 71(7):944-956 Doi: 10.1111/all.12858 [OPEN ACCESS]
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Radnai, B; Sturm, EM; Stančić, A; Jandl, K; Labocha, S; Ferreirós, N; Grill, M; Hasenoehrl, C; Gorkiewicz, G; Marsche, G; Heinemann, Á; Högenauer, C; Schicho, R Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn's Disease.
J Crohns Colitis. 2016; 10(9):1087-1095 Doi: 10.1093/ecco-jcc/jjw061 [OPEN ACCESS]
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2015

Fattahi, F; Vonk, JM; Bulkmans, N; Fleischeuer, R; Gouw, A; Grünberg, K; Mauad, T; Popper, H; Felipe-Silva, A; Vrugt, B; Wright, JL; Yang, HM; Kocks, JW; Hylkema, MN; Postma, DS; Timens, W; Ten Hacken, NH Old dilemma: asthma with irreversible airway obstruction or COPD.
Virchows Arch. 2015; 467(5):583-593 Doi: 10.1007/s00428-015-1824-6 [OPEN ACCESS]
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Harbaum, L; Pollheimer, MJ; Kornprat, P; Lindtner, RA; Bokemeyer, C; Langner, C Peritumoral eosinophils predict recurrence in colorectal cancer.
Mod Pathol. 2015; 28(3):403-413 Doi: 10.1038/modpathol.2014.104 [OPEN ACCESS]
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Schlager, S; Goeritzer, M; Jandl, K; Frei, R; Vujic, N; Kolb, D; Strohmaier, H; Dorow, J; Eichmann, TO; Rosenberger, A; Wölfler, A; Lass, A; Kershaw, EE; Ceglarek, U; Dichlberger, A; Heinemann, A; Kratky, D Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.
J Leukoc Biol. 2015; 98(5):837-50 Doi: 10.1189/jlb.3A0515-206R [OPEN ACCESS]
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Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
Eur J Immunol. 2015; 45(5):1548-1559 Doi: 10.1002/eji.201445196 [OPEN ACCESS]
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2014

Konya, V; Blättermann, S; Jandl, K; Platzer, W; Ottersbach, PA; Marsche, G; Gütschow, M; Kostenis, E; Heinemann, A A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
J Immunol. 2014; 192(10):4774-4782 Doi: 10.4049/jimmunol.1302013 [OPEN ACCESS]
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Konya, V; Peinhaupt, M; Heinemann, A Adhesion of eosinophils to endothelial cells or substrates under flow conditions.
Methods Mol Biol. 2014; 1178(5):143-156 Doi: 10.1007/978-1-4939-1016-8_13
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Luschnig, P; Frei, R; Lang-Loidolt, D; Rozsasi, A; Tomazic, PV; Lippe, IT; Schuligoi, R; Heinemann, A Altered inhibitory function of the E-type prostanoid receptor 4 in eosinophils and monocytes from aspirin-intolerant patients.
Pharmacology. 2014; 94(5-6):280-286 Doi: 10.1159/000369827
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Massone, C; Cerroni, L; Heidrun, N; Brunasso, AM; Nunzi, E; Gulia, A; Ambros-Rudolph, CM Histopathological diagnosis of atopic eruption of pregnancy and polymorphic eruption of pregnancy: a study on 41 cases.
Am J Dermatopathol. 2014; 36(10):812-821 Doi: 10.1097/DAD.0000000000000067
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Sturm, EM; Radnai, B; Jandl, K; Stančić, A; Parzmair, GP; Högenauer, C; Kump, P; Wenzl, H; Petritsch, W; Pieber, TR; Schuligoi, R; Marsche, G; Ferreirós, N; Heinemann, A; Schicho, R Opposing roles of prostaglandin D2 receptors in ulcerative colitis.
J Immunol. 2014; 193(2):827-839 Doi: 10.4049/jimmunol.1303484 [OPEN ACCESS]
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Wutte, N; Palfner, M; Auer, H; Ruckenbauer, G; Valentin, T; Seeber, K; Aberer, W; Krause, R; Hoenigl, M Toxocarosis and putative DRESS syndrome in an oncological patient: a case report.
Wien Klin Wochenschr. 2014; 126 Suppl 1(2):S51-S55 Doi: 10.1007/s00508-013-0444-x (- Case Report)
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2013

Dyer, KD; Garcia-Crespo, KE; Percopo, CM; Sturm, EM; Rosenberg, HF Protocols for identifying, enumerating, and assessing mouse eosinophils.
Methods Mol Biol. 2013; 1032(12):59-77 Doi: 10.1007/978-1-62703-496-8_5
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Singer, F; Luchsinger, I; Inci, D; Knauer, N; Latzin, P; Wildhaber, JH; Moeller, A Exhaled nitric oxide in symptomatic children at preschool age predicts later asthma.
Allergy. 2013; 68(4):531-8 Doi: 10.1111/all.12127
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Sturm, EM; Dyer, KD; Percopo, CM; Heinemann, A; Rosenberg, HF Chemotaxis of bone marrow derived eosinophils in vivo: a novel method to explore receptor-dependent trafficking in the mouse.
Eur J Immunol. 2013; 43(8):2217-2228 Doi: 10.1002/eji.201343371 [OPEN ACCESS]
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Thiel, J; Hässler, F; Salzer, U; Voll, RE; Venhoff, N Rituximab in the treatment of refractory or relapsing eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome).
ARTHRITIS RES THER. 2013; 15(5): R133 Doi: 10.1186/ar4313 [OPEN ACCESS]
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Wiednig, M; Beham-Schmid, C; Kranzelbinder, B; Aberer, E Clonal mast cell proliferation in pruriginous skin in hypereosinophilic syndrome.
Dermatology. 2013; 227(1):67-71 Doi: 10.1159/000351807 (- Case Report) [OPEN ACCESS]
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2012

Fazekas, T; Pruckner, N; Lawitschka, A; Seidel, MG; Eickhoff, P; Pötschger, U; Szpfalusi, Z; Gadner, H; Peters, C Non-atopic IgE and eosinophil cationic protein after allogeneic hematopoietic stem cell transplantation in children.
Ann Hematol. 2012; 91(6):949-956 Doi: 10.1007/s00277-011-1402-1 [OPEN ACCESS]
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Schröder, R; Xue, L; Konya, V; Martini, L; Kampitsch, N; Whistler, JL; Ulven, T; Heinemann, A; Pettipher, R; Kostenis, E PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2.
PLoS One. 2012; 7(3):e33329-e33329 Doi: 10.1371/journal.pone.0033329 [OPEN ACCESS]
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Sedej, M; Schröder, R; Bell, K; Platzer, W; Vukoja, A; Kostenis, E; Heinemann, A; Waldhoer, M D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.
J Allergy Clin Immunol. 2012; 129(2): 500.e1- 500.e9 Doi: 10.1016/j.jaci.2011.08.015
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2011

Konya, V; Philipose, S; Bálint, Z; Olschewski, A; Marsche, G; Sturm, EM; Schicho, R; Peskar, BA; Schuligoi, R; Heinemann, A Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors.
Eur J Immunol. 2011; 41(8):2379-2389 Doi: 10.1002/eji.201141460 [OPEN ACCESS]
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Luschnig-Schratl, P; Sturm, EM; Konya, V; Philipose, S; Marsche, G; Fröhlich, E; Samberger, C; Lang-Loidolt, D; Gattenlöhner, S; Lippe, IT; Peskar, BA; Schuligoi, R; Heinemann, A EP4 receptor stimulation down-regulates human eosinophil function.
Cell Mol Life Sci. 2011; 68(21): 3573-3587. Doi: 10.1007/s00018-011-0642-5 [OPEN ACCESS]
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Müller, CS; El Shabrawi-Caelen, L "Follicular Swiss cheese" pattern--another histopathologic clue to alopecia areata.
J Cutan Pathol. 2011; 38(2):185-189 Doi: 10.1111/j.1600-0560.2010.01640.x
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