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Abdel-Aziz, MI; Thorsen, J; Hashimoto, S; Vijverberg, SJH; Neerincx, AH; Brinkman, P; van, Aalderen, W; Stokholm, J; Rasmussen, MA; Roggenbuck-Wedemeyer, M; Vissing, NH; Mortensen, MS; Brejnrod, AD; Fleming, LJ; Murray, CS; Fowler, SJ; Frey, U; Bush, A; Singer, F; Hedlin, G; Nordlund, B; Shaw, DE; Chung, KF; Adcock, IM; Djukanovic, R; Auffray, C; Bansal, AT; Sousa, AR; Wagers, SS; Chawes, BL; Bønnelykke, K; Sørensen, SJ; Kraneveld, AD; Sterk, PJ; Roberts, G; Bisgaard, H; Maitland-van, der, Zee, AH
Oropharyngeal Microbiota Clusters in Children with Asthma/Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways and Exacerbations Risk.
Am J Respir Crit Care Med. 2023;
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Alcaniz, J; Winkler, L; Dahlmann, M; Becker, M; Orthmann, A; Haybaeck, J; Krassnig, S; Skofler, C; Kratzsch, T; Kuhn, SA; Jödicke, A; Linnebacher, M; Fichtner, I; Walther, W; Hoffmann, J
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Front Oncol. 2023; 13: 1129627
Doi: 10.3389/fonc.2023.1129627
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Badi, YE; Pavel, AB; Pavlidis, S; Riley, JH; Bates, S; Kermani, NZ; Knowles, R; Kolmert, J; Wheelock, CE; Worsley, S; Uddin, M; Alving, K; Bakke, PS; Behndig, A; Caruso, M; Chanez, P; Fleming, LJ; Fowler, SJ; Frey, U; Howarth, P; Horváth, I; Krug, N; Maitland-van, der, Zee, AH; Montuschi, P; Roberts, G; Sanak, M; Shaw, DE; Singer, F; Sterk, PJ; Djukanovic, R; Dahlen, SE; Guo, YK; Chung, KF; Guttman-Yassky, E; Adcock, IM, , U-BIOPRED, Study, Group
Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma.
J Allergy Clin Immunol. 2022; 149(1):89-101
Doi: 10.1016/j.jaci.2021.04.010
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Behringer, A; Stoimenovski, D; Porsch, M; Hoffmann, K; Behre, G; Grosse, I; Kalinski, T; Haybaeck, J; Nass, N
Relationship of micro-RNA, mRNA and eIF Expression in Tamoxifen-Adapted MCF-7 Breast Cancer Cells: Impact of miR-1972 on Gene Expression, Proliferation and Migration.
Biomolecules. 2022; 12(7):
Doi: 10.3390/biom12070916
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Eyileten, C; Wicik, Z; Keshwani, D; Aziz, F; Aberer, F; Pferschy, PN; Tripolt, NJ; Sourij, C; Prietl, B; Prüller, F; von, Lewinski, D; De, Rosa, S; Siller-Matula, JM; Postula, M; Sourij, H
Alteration of circulating platelet-related and diabetes-related microRNAs in individuals with type 2 diabetes mellitus: a stepwise hypoglycaemic clamp study.
Cardiovasc Diabetol. 2022; 21(1): 79
Doi: 10.1186/s12933-022-01517-5
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Jackson, H; Rivero, Calle, I; Broderick, C; Habgood-Coote, D; D'Souza, G; Nichols, S; Vito, O; Gómez-Rial, J; Rivero-Velasco, C; Rodríguez-Núñez, N; Barbeito-Castiñeiras, G; Pérez-Freixo, H; Barreiro-de, Acosta, M; Cunnington, AJ; Herberg, JA; Wright, VJ; Gómez-Carballa, A; Salas, A; Levin, M; Martinon-Torres, F; Kaforou, M, , GEN-COVID, (www.gencovid.eu), study, group;PERFORM, consortium
Characterisation of the blood RNA host response underpinning severity in COVID-19 patients.
Sci Rep. 2022; 12(1): 12216
Doi: 10.1038/s41598-022-15547-2
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Mathey, CM; Maj, C; Scheer, AB; Fazaal, J; Wedi, B; Wieczorek, D; Amann, PM; Löffler, H; Koch, L; Schöffl, C; Dickel, H; Ganjuur, N; Hornung, T; Forkel, S; Greve, J; Wurpts, G; Hallberg, P; Bygum, A; Von, Buchwald, C; Karawajczyk, M; Steffens, M; Stingl, J; Hoffmann, P; Heilmann-Heimbach, S; Mangold, E; Ludwig, KU; Rasmussen, ER; Wadelius, M; Sachs, B; Nöthen, MM; Forstner, AJ
Molecular Genetic Screening in Patients With ACE Inhibitor/Angiotensin Receptor Blocker-Induced Angioedema to Explore the Role of Hereditary Angioedema Genes.
Front Genet. 2022; 13: 914376
Doi: 10.3389/fgene.2022.914376
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Mishra, A; Duplaà, C; Vojinovic, D; Suzuki, H; Sargurupremraj, M; Zilhão, NR; Li, S; Bartz, TM; Jian, X; Zhao, W; Hofer, E; Wittfeld, K; Harris, SE; van, der, Auwera-Palitschka, S; Luciano, M; Bis, JC; Adams, HHH; Satizabal, CL; Gottesman, RF; Gampawar, PG; Bülow, R; Weiss, S; Yu, M; Bastin, ME; Lopez, OL; Vernooij, MW; Beiser, AS; Völker, U; Kacprowski, T; Soumare, A; Smith, JA; Knopman, DS; Morris, Z; Zhu, Y; Rotter, JI; Dufouil, C; Valdés, Hernández, M; Muñoz, Maniega, S; Lathrop, M; Boerwinkle, E; Schmidt, R; Ihara, M; Mazoyer, B; Yang, Q; Joutel, A; Tournier-Lasserve, E; Launer, LJ; Deary, IJ; Mosley, TH; Amouyel, P; DeCarli, CS; Psaty, BM; Tzourio, C; Kardia, SLR; Grabe, HJ; Teumer, A; van, Duijn, CM; Schmidt, H; Wardlaw, JM; Ikram, MA; Fornage, M; Gudnason, V; Seshadri, S; Matthews, PM; Longstreth, WT; Couffinhal, T; Debette, S
Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.
Brain. 2022; 145(6): 1992-2007.
Doi: 10.1093/brain/awab432
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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Am J Hum Genet. 2022; 109(8): 1366-1387.
Doi: 10.1016/j.ajhg.2022.06.012
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Reinke, SN; Naz, S; Chaleckis, R; Gallart-Ayala, H; Kolmert, J; Kermani, NZ; Tiotiu, A; Broadhurst, DI; Lundqvist, A; Olsson, H; Ström, M; Wheelock, ÅM; Gómez, C; Ericsson, M; Sousa, AR; Riley, JH; Bates, S; Scholfield, J; Loza, M; Baribaud, F; Bakke, PS; Caruso, M; Chanez, P; Fowler, SJ; Geiser, T; Howarth, P; Horváth, I; Krug, N; Montuschi, P; Behndig, A; Singer, F; Musial, J; Shaw, DE; Dahlén, B; Hu, S; Lasky-Su, J; Sterk, PJ; Chung, KF; Djukanovic, R; Dahlén, SE; Adcock, IM; Wheelock, CE, , U-BIOPRED, Study, Group
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Eur Respir J. 2022; 59(6):
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Shi, W; Li, C; Wartmann, T; Kahlert, C; Du, R; Perrakis, A; Brunner, T; Croner, RS; Kahlert, UD
Sensory Ion Channel Candidates Inform on the Clinical Course of Pancreatic Cancer and Present Potential Targets for Repurposing of FDA-Approved Agents.
J Pers Med. 2022; 12(3):
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Stachon, T; Nastaranpour, M; Seitz, B; Meese, E; Latta, L; Taneri, S; Ardjomand, N; Szentmáry, N; Ludwig, N
Altered Regulation of mRNA and miRNA Expression in Epithelial and Stromal Tissue of Keratoconus Corneas.
Invest Ophthalmol Vis Sci. 2022; 63(8): 7
Doi: 10.1167/iovs.63.8.7
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Wicik, Z; Nowak, A; Jarosz-Popek, J; Wolska, M; Eyileten, C; Siller-Matula, JM; von, Lewinski, D; Sourij, H; Filipiak, KJ; Postuła, M
Characterization of the SGLT2 Interaction Network and Its Regulation by SGLT2 Inhibitors: A Bioinformatic Analysis.
Front Pharmacol. 2022; 13: 901340
Doi: 10.3389/fphar.2022.901340
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Darnhofer, B; Tomin, T; Liesinger, L; Schittmayer, M; Tomazic, PV; Birner-Gruenberger, R
Comparative proteomics of common allergenic tree pollens of birch, alder, and hazel.
Allergy. 2021; 76(6):1743-1753
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Dengler, MA; Gibson, L; Adams, JM
BAX mitochondrial integration is regulated allosterically by its α1-α2 loop.
Cell Death Differ. 2021; 28(12):3270-3281
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Eisenwort, G; Sadovnik, I; Keller, A; Ivanov, D; Peter, B; Berger, D; Stefanzl, G; Bauer, K; Slavnitsch, K; Greiner, G; Gleixner, KV; Sperr, WR; Willmann, M; Sill, H; Bettelheim, P; Geissler, K; Deininger, M; Rülicke, T; Valent, P
Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia.
Leukemia. 2021; 35(11):3176-3187
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Fan, K; Spassova, I; Gravemeyer, J; Ritter, C; Horny, K; Lange, A; Gambichler, T; Ødum, N; Schrama, D; Schadendorf, D; Ugurel, S; Becker, JC
Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53.
Oncogene. 2021; 40(5):980-996
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Fischer, C; Koblmüller, S; Börger, C; Michelitsch, G; Trajanoski, S; Schlötterer, C; Guelly, C; Thallinger, GG; Sturmbauer, C
Genome sequences of Tropheus moorii and Petrochromis trewavasae, two eco-morphologically divergent cichlid fishes endemic to Lake Tanganyika.
Sci Rep. 2021; 11(1):4309-4309
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Grill, M; Lazzeri, I; Kirsch, A; Steurer, N; Grossmann, T; Karbiener, M; Heitzer, E; Gugatschka, M
Vocal Fold Fibroblasts in Reinke's Edema Show Alterations Involved in Extracellular Matrix Production, Cytokine Response and Cell Cycle Control.
Biomedicines. 2021; 9(7):
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Karami, H; Derakhshani, A; Ghasemigol, M; Fereidouni, M; Miri-Moghaddam, E; Baradaran, B; Tabrizi, NJ; Najafi, S; Solimando, AG; Marsh, LM; Silvestris, N; De, Summa, S; Paradiso, AV; Racanelli, V; Safarpour, H
Weighted Gene Co-Expression Network Analysis Combined with Machine Learning Validation to Identify Key Modules and Hub Genes Associated with SARS-CoV-2 Infection.
J Clin Med. 2021; 10(16):
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Larose, H; Prokoph, N; Matthews, JD; Schlederer, M; Högler, S; Alsulami, AF; Ducray, SP; Nuglozeh, E; Fazaludeen, FMS; Elmouna, A; Ceccon, M; Mologni, L; Gambacorti-Passerini, C; Hoefler, G; Lobello, C; Pospisilova, S; Janikova, A; Woessmann, W; Damm-Welk, C; Zimmermann, M; Federova, A; Malone, A; Smith, O; Wasik, M; Inghirami, G; Lamant, L; Blundell, TL; Klapper, W; Merkel, O; Burke, AGA; Mian, S; Ashankyty, I; Kenner, L; Turner, SD
Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target.
HAEMATOLOGICA. 2021; 106(6): 1693-1704.
Doi: 10.3324/haematol.2019.238766
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Lesko, J; Triebl, A; Stacher-Priehse, E; Fink-Neuböck, N; Lindenmann, J; Smolle-Jüttner, FM; Köfeler, HC; Hrzenjak, A; Olschewski, H; Leithner, K
Phospholipid dynamics in ex vivo lung cancer and normal lung explants.
Exp Mol Med. 2021; 53(1):81-90
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Machan, S; Rodríguez, M; Alonso-Alonso, R; Manso, R; Pérez-Buira, S; Borregón, J; Rodríguez-Peralto, JL; Cerroni, L; Haro, R; García, C; García, Toro, E; Estrach, T; García-Herrera, A; Ferrer, B; González-Cruz, C; Segues, N; Afonso-Martin, JL; Peñate, Y; Monteagudo, C; Limeres-Gonzalez, MÁ; González-Núñez, MÁ; Torres, MÁT; Cereceda, L; Córdoba, R; Piris, MÁ; Requena, L; María, Rodríguez-Pinilla, S
Subcutaneous panniculitis-like T-cell lymphoma, lupus erythematosus profundus, and overlapping cases: molecular characterization through the study of 208 genes.
Leuk Lymphoma. 2021; 62(9):2130-2140
Doi: 10.1080/10428194.2021.1901098
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Mathilakathu, A; Borchert, S; Wessolly, M; Mairinger, E; Beckert, H; Steinborn, J; Hager, T; Christoph, DC; Kollmeier, J; Wohlschlaeger, J; Mairinger, T; Schmid, KW; Walter, RFH; Brcic, L; Mairinger, FD
Mitogen signal-associated pathways, energy metabolism regulation, and mediation of tumor immunogenicity play essential roles in the cellular response of malignant pleural mesotheliomas to platinum-based treatment: a retrospective study
TRANSL LUNG CANCER R. 2021;
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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
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Sensitive and broadly applicable residual disease detection in acute myeloid leukemia using flow cytometry-based leukemic cell enrichment followed by mutational profiling.
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Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
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In Vivo Detection of Circulating Tumor Cells in High-Risk Non-Metastatic Prostate Cancer Patients Undergoing Radiotherapy.
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New insights into human lysine degradation pathways with relevance to pyridoxine-dependent epilepsy due to antiquitin deficiency.
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Kunkle, BW; Grenier-Boley, B; Sims, R; Bis, JC; Damotte, V; Naj, AC; Boland, A; Vronskaya, M; van der Lee, SJ; Amlie-Wolf, A; Bellenguez, C; Frizatti, A; Chouraki, V; Martin, ER; Sleegers, K; Badarinarayan, N; Jakobsdottir, J; Hamilton-Nelson, KL; Moreno-Grau, S; Olaso, R; Raybould, R; Chen, Y; Kuzma, AB; Hiltunen, M; Morgan, T; Ahmad, S; Vardarajan, BN; Epelbaum, J; Hoffmann, P; Boada, M; Beecham, GW; Garnier, JG; Harold, D; Fitzpatrick, AL; Valladares, O; Moutet, ML; Gerrish, A; Smith, AV; Qu, L; Bacq, D; Denning, N; Jian, X; Zhao, Y; Del Zompo, M; Fox, NC; Choi, SH; Mateo, I; Hughes, JT; Adams, HH; Malamon, J; Sanchez-Garcia, F; Patel, Y; Brody, JA; Dombroski, BA; Naranjo, MCD; Daniilidou, M; Eiriksdottir, G; Mukherjee, S; Wallon, D; Uphill, J; Aspelund, T; Cantwell, LB; Garzia, F; Galimberti, D; Hofer, E; Butkiewicz, M; Fin, B; Scarpini, E; Sarnowski, C; Bush, WS; Meslage, S; Kornhuber, J; White, CC; Song, Y; Barber, RC; Engelborghs, S; Sordon, S; Voijnovic, D; Adams, PM; Vandenberghe, R; Mayhaus, M; Cupples, LA; Albert, MS; De Deyn, PP; Gu, W; Himali, JJ; Beekly, D; Squassina, A; Hartmann, AM; Orellana, A; Blacker, D; Rodriguez-Rodriguez, E; Lovestone, S; Garcia, ME; Doody, RS; Munoz-Fernadez, C; Sussams, R; Lin, H; Fairchild, TJ; Benito, YA; Holmes, C; Karamujić-Čomić, H; Frosch, MP; Thonberg, H; Maier, W; Roschupkin, G; Ghetti, B; Giedraitis, V; Kawalia, A; Li, S; Huebinger, RM; Kilander, L; Moebus, S; Hernández, I; Kamboh, MI; Brundin, R; Turton, J; Yang, Q; Katz, MJ; Concari, L; Lord, J; Beiser, AS; Keene, CD; Helisalmi, S; Kloszewska, I; Kukull, WA; Koivisto, AM; Lynch, A; Tarraga, L; Larson, EB; Haapasalo, A; Lawlor, B; Mosley, TH; Lipton, RB; Solfrizzi, V; Gill, M; Longstreth, WT; Montine, TJ; Frisardi, V; Diez-Fairen, M; Rivadeneira, F; Petersen, RC; Deramecourt, V; Alvarez, I; Salani, F; Ciaramella, A; Boerwinkle, E; Reiman, EM; Fievet, N; Rotter, JI; Reisch, JS; Hanon, O; Cupidi, C; Andre Uitterlinden, AG; Royall, DR; Dufouil, C; Maletta, RG; de Rojas, I; Sano, M; Brice, A; Cecchetti, R; George-Hyslop, PS; Ritchie, K; Tsolaki, M; Tsuang, DW; Dubois, B; Craig, D; Wu, CK; Soininen, H; Avramidou, D; Albin, RL; Fratiglioni, L; Germanou, A; Apostolova, LG; Keller, L; Koutroumani, M; Arnold, SE; Panza, F; Gkatzima, O; Asthana, S; Hannequin, D; Whitehead, P; Atwood, CS; Caffarra, P; Hampel, H; Quintela, I; Carracedo, Á; Lannfelt, L; Rubinsztein, DC; Barnes, LL; Pasquier, F; Frölich, L; Barral, S; McGuinness, B; Beach, TG; Johnston, JA; Becker, JT; Passmore, P; Bigio, EH; Schott, JM; Bird, TD; Warren, JD; Boeve, BF; Lupton, MK; Bowen, JD; Proitsi, P; Boxer, A; Powell, JF; Burke, JR; Kauwe, JSK; Burns, JM; Mancuso, M; Buxbaum, JD; Bonuccelli, U; Cairns, NJ; McQuillin, A; Cao, C; Livingston, G; Carlson, CS; Bass, NJ; Carlsson, CM; Hardy, J; Carney, RM; Bras, J; Carrasquillo, MM; Guerreiro, R; Allen, M; Chui, HC; Fisher, E; Masullo, C; Crocco, EA; DeCarli, C; Bisceglio, G; Dick, M; Ma, L; Duara, R; Graff-Radford, NR; Evans, DA; Hodges, A; Faber, KM; Scherer, M; Fallon, KB; Riemenschneider, M; Fardo, DW; Heun, R; Farlow, MR; Kölsch, H; Ferris, S; Leber, M; Foroud, TM; Heuser, I; Galasko, DR; Giegling, I; Gearing, M; Hüll, M; Geschwind, DH; Gilbert, JR; Morris, J; Green, RC; Mayo, K; Growdon, JH; Feulner, T; Hamilton, RL; Harrell, LE; Drichel, D; Honig, LS; Cushion, TD; Huentelman, MJ; Hollingworth, P; Hulette, CM; Hyman, BT; Marshall, R; Jarvik, GP; Meggy, A; Abner, E; Menzies, GE; Jin, LW; Leonenko, G; Real, LM; Jun, GR; Baldwin, CT ...
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Nat Genet. 2019; 51(3): 414-430.
Doi: 10.1038/s41588-019-0358-2
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Menzl, I; Zhang, T; Berger-Becvar, A; Grausenburger, R; Heller, G; Prchal-Murphy, M; Edlinger, L; Knab, VM; Uras, IZ; Grundschober, E; Bauer, K; Roth, M; Skucha, A; Liu, Y; Hatcher, JM; Liang, Y; Kwiatkowski, NP; Fux, D; Hoelbl-Kovacic, A; Kubicek, S; Melo, JV; Valent, P; Weichhart, T; Grebien, F; Zuber, J; Gray, NS; Sexl, V
A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.
Nat Commun. 2019; 10(1): 4741
Doi: 10.1038/s41467-019-12656-x
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Pepin, ME; Koentges, C; Pfeil, K; Gollmer, J; Kersting, S; Wiese, S; Hoffmann, MM; Odening, KE; von Zur Mühlen, C; Diehl, P; Stachon, P; Wolf, D; Wende, AR; Bode, C; Zirlik, A; Bugger, H
Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1.
Front Endocrinol (Lausanne). 2019; 10(1):872-872
Doi: 10.3389/fendo.2019.00872
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Pomares-Quimbaya, A; Kreuzthaler, M; Schulz, S
Current approaches to identify sections within clinical narratives from electronic health records: a systematic review.
BMC Med Res Methodol. 2019; 19(1):155-155
Doi: 10.1186/s12874-019-0792-y
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Porsch, M; Özdemir, E; Wisniewski, M; Graf, S; Bull, F; Hoffmann, K; Ignatov, A; Haybaeck, J; Grosse, I; Kalinski, T; Nass, N
Time resolved gene expression analysis during tamoxifen adaption of MCF-7 cells identifies long non-coding RNAs with prognostic impact.
RNA Biol. 2019; 16(5):661-674
Doi: 10.1080/15476286.2019.1581597
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Sapienza, MR; Abate, F; Melle, F; Orecchioni, S; Fuligni, F; Etebari, M; Tabanelli, V; Laginestra, MA; Pileri, A; Motta, G; Rossi, M; Agostinelli, C; Sabattini, E; Pimpinelli, N; Truni, M; Falini, B; Cerroni, L; Talarico, G; Piccioni, R; Amente, S; Indio, V; Tarantino, G; Brundu, F; Paulli, M; Berti, E; Facchetti, F; Dellino, GI; Bertolini, F; Tripodo, C; Rabadan, R; Pileri, SA
Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target.
HAEMATOLOGICA. 2019; 104(4): 729-737.
Doi: 10.3324/haematol.2018.202093
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