Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: AUTOPHAGY, . Treffer: 74

2020

Abdellatif, M; Ljubojevic-Holzer, S; Madeo, F; Sedej, S Autophagy in cardiovascular health and disease.
Prog Mol Biol Transl Sci. 2020; 172:87-106
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Panzitt, K; Jungwirth, E; Krones, E; Lee, JM; Pollheimer, M; Thallinger, GG; Kolb-Lenz, D; Xiao, R; Thorell, A; Trauner, M; Fickert, P; Marschall, HU; Moore, DD; Wagner, M FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
J Hepatol. 2020; 72(6):1122-1131 [OPEN ACCESS]
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Sallinger, M; Tiffner, A; Schmidt, T; Bonhenry, D; Waldherr, L; Frischauf, I; Lunz, V; Derler, I; Schober, R; Schindl, R Luminal STIM1 Mutants that Cause Tubular Aggregate Myopathy Promote Autophagic Processes
INT J MOL SCI. 2020; 21(12): 4410
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Sukseree, S; Schwarze, UY; Gruber, R; Gruber, F; Quiles Del Rey, M; Mancias, JD; Bartlett, JD; Tschachler, E; Eckhart, L ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging.
Autophagy. 2020; 1-7.
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2019

Baracco, EE; Castoldi, F; Durand, S; Enot, DP; Tadic, J; Kainz, K; Madeo, F; Chery, A; Izzo, V; Maiuri, MC; Pietrocola, F; Kroemer, G α-Ketoglutarate inhibits autophagy.
Aging (Albany NY). 2019; 11(11):3418-3431 [OPEN ACCESS]
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Carmona-Gutierrez, D; Zimmermann, A; Kainz, K; Pietrocola, F; Chen, G; Maglioni, S; Schiavi, A; Nah, J; Mertel, S; Beuschel, CB; Castoldi, F; Sica, V; Trausinger, G; Raml, R; Sommer, C; Schroeder, S; Hofer, SJ; Bauer, MA; Pendl, T; Tadic, J; Dammbrueck, C; Hu, Z; Ruckenstuhl, C; Eisenberg, T; Durand, S; Bossut, N; Aprahamian, F; Abdellatif, M; Sedej, S; Enot, DP; Wolinski, H; Dengjel, J; Kepp, O; Magnes, C; Sinner, F; Pieber, TR; Sadoshima, J; Ventura, N; Sigrist, SJ; Kroemer, G; Madeo, F The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Nat Commun. 2019; 10(1):651-651 [OPEN ACCESS]
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Denk, H; Stumptner, C; Abuja, PM; Zatloukal, K Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma.
Expert Opin Ther Targets. 2019; 23(5):393-406
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Gali, CC; Fanaee-Danesh, E; Zandl-Lang, M; Albrecher, NM; Tam-Amersdorfer, C; Stracke, A; Sachdev, V; Reichmann, F; Sun, Y; Avdili, A; Reiter, M; Kratky, D; Holzer, P; Lass, A; Kandimalla, KK; Panzenboeck, U Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Mol Cell Neurosci. 2019; 99: 103390-103390. [OPEN ACCESS]
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Gross, AS; Zimmermann, A; Pendl, T; Schroeder, S; Schoenlechner, H; Knittelfelder, O; Lamplmayr, L; Santiso, A; Aufschnaiter, A; Waltenstorfer, D; Ortonobes Lara, S; Stryeck, S; Kast, C; Ruckenstuhl, C; Hofer, SJ; Michelitsch, B; Woelflingseder, M; Müller, R; Carmona-Gutierrez, D; Madl, T; Büttner, S; Fröhlich, KU; Shevchenko, A; Eisenberg, T Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK.
J Biol Chem. 2019; 294(32): 12020-12039. [OPEN ACCESS]
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Lipovšek, S; Leitinger, G; Janžekovič, F; Kozel, P; Dariš, B; Perc, M; Devetak, D; Weiland, N; Novak, T Towards understanding partial adaptation to the subterranean habitat in the European cave spider, Meta menardi: An ecocytological approach.
Sci Rep. 2019; 9(1): 9121-9121. [OPEN ACCESS]
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Ong, SB; Lee, WH; Shao, NY; Ismail, NI; Katwadi, K; Lim, MM; Kwek, XY; Michel, NA; Li, J; Newson, J; Tahmasebi, S; Rehman, J; Kodo, K; Jang, HR; Ong, SG Calpain Inhibition Restores Autophagy and Prevents Mitochondrial Fragmentation in a Human iPSC Model of Diabetic Endotheliopathy.
Stem Cell Reports. 2019; 12(3):597-610 [OPEN ACCESS]
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Schober, R; Waldherr, L; Schmidt, T; Graziani, A; Stilianu, C; Legat, L; Groschner, K; Schindl, R STIM1 and Orai1 regulate Ca2+ microdomains for activation of transcription.
Biochim Biophys Acta Mol Cell Res. 2019; 1866(7):1079-1091
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Zimmermann, A; Kainz, K; Hofer, SJ; Bauer, MA; Schroeder, S; Dengjel, J; Pietrocola, F; Kepp, O; Ruckenstuhl, C; Eisenberg, T; Sigrist, SJ; Madeo, F; Carmona-Gutierrez, D; Kroemer, G 4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects.
Autophagy. 2019; 15(9):1662-1664 [OPEN ACCESS]
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Zimmermann, A; Kainz, K; Hofer, SJ; Bauer, MA; Schroeder, S; Dengjel, J; Pietrocola, F; Kepp, O; Ruckenstuhl, C; Eisenberg, T; Sigrist, SJ; Madeo, F; Kroemer, G; Carmona-Gutierrez, D Targeting GATA transcription factors - a novel strategy for anti-aging interventions?
Microb Cell. 2019; 6(5):212-216 [OPEN ACCESS]
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2018

Abdellatif, M; Sedej, S; Carmona-Gutierrez, D; Madeo, F; Kroemer, G Autophagy in Cardiovascular Aging.
Circ Res. 2018; 123(7):803-824 [OPEN ACCESS]
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Frauscher, B; Kirsch, AH; Schabhüttl, C; Schweighofer, K; Kétszeri, M; Pollheimer, M; Dragun, D; Schröder, K; Rosenkranz, AR; Eller, K; Eller, P Autophagy Protects From Uremic Vascular Media Calcification.
Front Immunol. 2018; 9(5):1866-1866 [OPEN ACCESS]
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Gauster, M; Maninger, S; Siwetz, M; Deutsch, A; El-Heliebi, A; Kolb-Lenz, D; Hiden, U; Desoye, G; Herse, F; Prokesch, A Downregulation of p53 drives autophagy during human trophoblast differentiation.
Cell Mol Life Sci. 2018; 75(10):1839-1855 [OPEN ACCESS]
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Hutabarat, M; Wibowo, N; Obermayer-Pietsch, B; Huppertz, B Impact of vitamin D and vitamin D receptor on the trophoblast survival capacity in preeclampsia.
PLoS One. 2018; 13(11):e0206725-e0206725 [OPEN ACCESS]
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Jahanafrooz, Z; Motamed, N; Rinner, B; Mokhtarzadeh, A; Baradaran, B Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator.
Life Sci. 2018; 213:236-247
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Kolb-Lenz, D; Fuchs, R; Lohberger, B; Heitzer, E; Meditz, K; Pernitsch, D; Pritz, E; Groselj-Strele, A; Leithner, A; Liegl-Atzwanger, B; Rinner, B Characterization of the endolysosomal system in human chordoma cell lines: is there a role of lysosomes in chemoresistance of this rare bone tumor?
Histochem Cell Biol. 2018; 150(1): 83-92. [OPEN ACCESS]
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Kretschmer, N; Deutsch, A; Durchschein, C; Rinner, B; Stallinger, A; Higareda-Almaraz, JC; Scheideler, M; Lohberger, B; Bauer, R Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction.
Molecules. 2018; 23(11): [OPEN ACCESS]
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Kuscuoglu, D; Janciauskiene, S; Hamesch, K; Haybaeck, J; Trautwein, C; Strnad, P Liver - master and servant of serum proteome.
J Hepatol. 2018; 69(2):512-524
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Lipovšek, S; Leitinger, G; Novak, T; Janžekovič, F; Gorgoń, S; Kamińska, K; Rost-Roszkowska, M Changes in the midgut cells in the European cave spider, Meta menardi, during starvation in spring and autumn.
Histochem Cell Biol. 2018; 149(3):245-260
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Schwarz, C; Stekovic, S; Wirth, M; Benson, G; Royer, P; Sigrist, SJ; Pieber, T; Dammbrueck, C; Magnes, C; Eisenberg, T; Pendl, T; Bohlken, J; Köbe, T; Madeo, F; Flöel, A Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline.
Aging (Albany NY). 2018; [OPEN ACCESS]
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Sukseree, S; László, L; Gruber, F; Bergmann, S; Narzt, MS; Nagelreiter, IM; Höftberger, R; Molnár, K; Rauter, G; Birngruber, T; Larue, L; Kovacs, GG; Tschachler, E; Eckhart, L Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7.
Mol Neurobiol. 2018; 55(11):8425-8437 [OPEN ACCESS]
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Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 [OPEN ACCESS]
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2017

Aigelsreiter, A; Neumann, J; Pichler, M; Halasz, J; Zatloukal, K; Berghold, A; Douschan, P; Rainer, F; Stauber, R; Haybaeck, J; Denk, H; Lackner, C Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis.
Liver Int. 2017; 37(4):600-610
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Eisenberg, T; Abdellatif, M; Zimmermann, A; Schroeder, S; Pendl, T; Harger, A; Stekovic, S; Schipke, J; Magnes, C; Schmidt, A; Ruckenstuhl, C; Dammbrueck, C; Gross, AS; Herbst, V; Carmona-Gutierrez, D; Pietrocola, F; Pieber, TR; Sigrist, SJ; Linke, WA; Mühlfeld, C; Sadoshima, J; Dengjel, J; Kiechl, S; Kroemer, G; Sedej, S; Madeo, F Dietary spermidine for lowering high blood pressure.
Autophagy. 2017; 13(4):767-769 [OPEN ACCESS]
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Hutabarat, M; Wibowo, N; Huppertz, B ROLE OF AUTOPHAGY AS TROPHOBLAST SURVIVAL MECHANISM IN PREECLAMPSIA
PLACENTA. 2017; 57: 278-279.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); AUG 30-SEP 02, 2017; Manchester, ENGLAND. [Poster]
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Hutabarat, M; Wibowo, N; Huppertz, B The trophoblast survival capacity in preeclampsia.
PLOS ONE. 2017; 12(11): e0186909-e0186909. [OPEN ACCESS]
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Mehta, AK; Hua, K; Whipple, W; Nguyen, MT; Liu, CT; Haybaeck, J; Weidhaas, J; Settleman, J; Singh, A Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells.
Sci Signal. 2017; 10(496): [OPEN ACCESS]
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Prokesch, A; Blaschitz, A; Bauer, T; Moser, G; Hiden, U; Zadora, J; Dechend, R; Herse, F; Gauster, M Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-α in a gestational age-dependent manner.
Histochem Cell Biol. 2017; 147(6):695-705 [OPEN ACCESS]
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Stryeck, S; Birner-Gruenberger, R; Madl, T Integrative metabolomics as emerging tool to study autophagy regulation.
Microb Cell. 2017; 4(8):240-258 [OPEN ACCESS]
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2016

Eisenberg, T; Abdellatif, M; Schroeder, S; Primessnig, U; Stekovic, S; Pendl, T; Harger, A; Schipke, J; Zimmermann, A; Schmidt, A; Tong, M; Ruckenstuhl, C; Dammbrueck, C; Gross, AS; Herbst, V; Magnes, C; Trausinger, G; Narath, S; Meinitzer, A; Hu, Z; Kirsch, A; Eller, K; Carmona-Gutierrez, D; Büttner, S; Pietrocola, F; Knittelfelder, O; Schrepfer, E; Rockenfeller, P; Simonini, C; Rahn, A; Horsch, M; Moreth, K; Beckers, J; Fuchs, H; Gailus-Durner, V; Neff, F; Janik, D; Rathkolb, B; Rozman, J; de Angelis, MH; Moustafa, T; Haemmerle, G; Mayr, M; Willeit, P; von Frieling-Salewsky, M; Pieske, B; Scorrano, L; Pieber, T; Pechlaner, R; Willeit, J; Sigrist, SJ; Linke, WA; Mühlfeld, C; Sadoshima, J; Dengjel, J; Kiechl, S; Kroemer, G; Sedej, S; Madeo, F Cardioprotection and lifespan extension by the natural polyamine spermidine.
Nat Med. 2016; 22(12):1428-1438 [OPEN ACCESS]
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Fröhlich, LF; Mrakovcic, M; Smole, C; Zatloukal, K Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway.
Cancer Cell Int. 2016; 16(1):68-68 [OPEN ACCESS]
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Lohberger, B; Steinecker-Frohnwieser, B; Stuendl, N; Kaltenegger, H; Leithner, A; Rinner, B The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy.
PLoS One. 2016; 11(12):e0168193-e0168193 [OPEN ACCESS]
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Sturmberger, L; Chappell, T; Geier, M; Krainer, F; Day, KJ; Vide, U; Trstenjak, S; Schiefer, A; Richardson, T; Soriaga, L; Darnhofer, B; Birner-Gruenberger, R; Glick, BS; Tolstorukov, I; Cregg, J; Madden, K; Glieder, A Refined Pichia pastoris reference genome sequence.
J Biotechnol. 2016; 235(6):121-131 [OPEN ACCESS]
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Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165 [OPEN ACCESS]
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Yang, H; Ni, HM; Guo, F; Ding, Y; Shi, YH; Lahiri, P; Fröhlich, LF; Rülicke, T; Smole, C; Schmidt, VC; Zatloukal, K; Cui, Y; Komatsu, M; Fan, J; Ding, WX Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice.
J Biol Chem. 2016; 291(36):18663-18674 [OPEN ACCESS]
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Zhang, MH; Knisely, AS; Wang, NL; Gong, JY; Wang, JS Fibrinogen storage disease in a Chinese boy with de novo fibrinogen Aguadilla mutation: Incomplete response to carbamazepine and ursodeoxycholic acid.
BMC Gastroenterol. 2016; 16(1):92-92 (- Case Report) [OPEN ACCESS]
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Zimmermann, A; Kainz, K; Andryushkova, A; Hofer, S; Madeo, F; Carmona-Gutierrez, D Autophagy: one more Nobel Prize for yeast.
Microb Cell. 2016; 3(12): 579-581. [OPEN ACCESS]
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2015

Goeritzer, M; Vujic, N; Schlager, S; Chandak, PG; Korbelius, M; Gottschalk, B; Leopold, C; Obrowsky, S; Rainer, S; Doddapattar, P; Aflaki, E; Wegscheider, M; Sachdev, V; Graier, WF; Kolb, D; Radovic, B; Kratky, D Active autophagy but not lipophagy in macrophages with defective lipolysis.
Biochim Biophys Acta. 2015; 1851(10):1304-1316 [OPEN ACCESS]
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Lipovšek, S; Novak, T; Janžekovič, F; Leitinger, G Changes in the midgut diverticula in the harvestmen Amilenus aurantiacus (Phalangiidae, Opiliones) during winter diapause.
Arthropod Struct Dev. 2015; 44(2):131-141
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Musumeci, G; Castrogiovanni, P; Trovato, FM; Weinberg, AM; Al-Wasiyah, MK; Alqahtani, MH; Mobasheri, A Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis.
Int J Mol Sci. 2015; 16(9):20560-20575 [OPEN ACCESS]
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Wang, T; Hay, JC Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons Disease.
Front Neurosci. 2015; 9(3):433-433 [OPEN ACCESS]
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2014

Bugger, H; Abel, ED Molecular mechanisms of diabetic cardiomyopathy.
Diabetologia. 2014; 57(4): 660-671. [OPEN ACCESS]
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Büttner, S; Broeskamp, F; Sommer, C; Markaki, M; Habernig, L; Alavian-Ghavanini, A; Carmona-Gutierrez, D; Eisenberg, T; Michael, E; Kroemer, G; Tavernarakis, N; Sigrist, SJ; Madeo, F Spermidine protects against α-synuclein neurotoxicity.
Cell Cycle. 2014; 13(24):3903-3908 [OPEN ACCESS]
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Eisenberg, T; Schroeder, S; Andryushkova, A; Pendl, T; Küttner, V; Bhukel, A; Mariño, G; Pietrocola, F; Harger, A; Zimmermann, A; Moustafa, T; Sprenger, A; Jany, E; Büttner, S; Carmona-Gutierrez, D; Ruckenstuhl, C; Ring, J; Reichelt, W; Schimmel, K; Leeb, T; Moser, C; Schatz, S; Kamolz, LP; Magnes, C; Sinner, F; Sedej, S; Fröhlich, KU; Juhasz, G; Pieber, TR; Dengjel, J; Sigrist, SJ; Kroemer, G; Madeo, F Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.
Cell Metab. 2014; 19(3):431-444 [OPEN ACCESS]
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Eisenberg, T; Schroeder, S; Büttner, S; Carmona-Gutierrez, D; Pendl, T; Andryushkova, A; Mariño, G; Pietrocola, F; Harger, A; Zimmermann, A; Magnes, C; Sinner, F; Sedej, S; Pieber, TR; Dengjel, J; Sigrist, S; Kroemer, G; Madeo, F A histone point mutation that switches on autophagy.
Autophagy. 2014; 10(6):1143-1145 [OPEN ACCESS]
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Lee, JM; Wagner, M; Xiao, R; Kim, KH; Feng, D; Lazar, MA; Moore, DD Nutrient-sensing nuclear receptors coordinate autophagy.
Nature. 2014; 516(7529): 112-115. [OPEN ACCESS]
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