Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: TUMOR SUPPRESSOR PROTEIN P53 - GENETICS, . Treffer: 39

2018

Krstic, J; Reinisch, I; Schupp, M; Schulz, TJ; Prokesch, A p53 Functions in Adipose Tissue Metabolism and Homeostasis.
Int J Mol Sci. 2018; 19(9): [OPEN ACCESS]
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2017

González-Vela, MDC; Curiel-Olmo, S; Derdak, S; Beltran, S; Santibañez, M; Martínez, N; Castillo-Trujillo, A; Gut, M; Sánchez-Pacheco, R; Almaraz, C; Cereceda, L; Llombart, B; Agraz-Doblas, A; Revert-Arce, J; López Guerrero, JA; Mollejo, M; Marrón, PI; Ortiz-Romero, P; Fernandez-Cuesta, L; Varela, I; Gut, I; Cerroni, L; Piris, MÁ; Vaqué, JP Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas.
J Invest Dermatol. 2017; 137(1):197-206 [OPEN ACCESS]
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Kashofer, K; Regauer, S Analysis of full coding sequence of the TP53 gene in invasive vulvar cancers: Implications for therapy.
GYNECOL ONCOL. 2017; 146(2): 314-318.
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Kashofer, K; Winter, E; Halbwedl, I; Thueringer, A; Kreiner, M; Sauer, S; Regauer, S HPV-negative penile squamous cell carcinoma: disruptive mutations in the TP53 gene are common.
Mod Pathol. 2017; 30(7):1013-1020 [OPEN ACCESS]
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Lax, SF Pathology of Endometrial Carcinoma.
Adv Exp Med Biol. 2017; 943(4):75-96
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 [OPEN ACCESS]
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2016

Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
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Sigl, V; Owusu-Boaitey, K; Joshi, PA; Kavirayani, A; Wirnsberger, G; Novatchkova, M; Kozieradzki, I; Schramek, D; Edokobi, N; Hersl, J; Sampson, A; Odai-Afotey, A; Lazaro, C; Gonzalez-Suarez, E; Pujana, MA; Cimba, F; Heyn, H; Vidal, E; Cruickshank, J; Berman, H; Sarao, R; Ticevic, M; Uribesalgo, I; Tortola, L; Rao, S; Tan, Y; Pfeiler, G; Lee, EY; Bago-Horvath, Z; Kenner, L; Popper, H; Singer, C; Khokha, R; Jones, LP; Penninger, JM RANKL/RANK control Brca1 mutation- .
Cell Res. 2016; 26(7):761-774 [OPEN ACCESS]
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Zhang, F; Li, M; Su, Y; Zhou, J; Wang, W A dual-targeting drug co-delivery system for tumor chemo- and gene combined therapy.
Mater Sci Eng C Mater Biol Appl. 2016; 64(28): 208-218.
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2015

Kandioler, D; Mittlböck, M; Kappel, S; Puhalla, H; Herbst, F; Langner, C; Wolf, B; Tschmelitsch, J; Schippinger, W; Steger, G; Hofbauer, F; Samonigg, H; Gnant, M; Teleky, B; Kührer, I; p53 Research Group and the Austrian Breast and Colorectal Study Group (ABCSG) TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients.
EBioMedicine. 2015; 2(8):825-830 [OPEN ACCESS]
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Leithner, K; Hrzenjak, A; Trötzmüller, M; Moustafa, T; Köfeler, HC; Wohlkoenig, C; Stacher, E; Lindenmann, J; Harris, AL; Olschewski, A; Olschewski, H PCK2 activation mediates an adaptive response to glucose depletion in lung cancer.
Oncogene. 2015; 34(8):1044-1050
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Schulz, E; Kashofer, K; Heitzer, E; Mhatre, KN; Speicher, MR; Hoefler, G; Sill, H Preexisting TP53 mutation in therapy-related acute myeloid leukemia.
Ann Hematol. 2015; 94(3):527-529 (- Case Report) [OPEN ACCESS]
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Zuckermann, M; Hovestadt, V; Knobbe-Thomsen, CB; Zapatka, M; Northcott, PA; Schramm, K; Belic, J; Jones, DT; Tschida, B; Moriarity, B; Largaespada, D; Roussel, MF; Korshunov, A; Reifenberger, G; Pfister, SM; Lichter, P; Kawauchi, D; Gronych, J Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.
Nat Commun. 2015; 6(3):7391-7391 [OPEN ACCESS]
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2014

Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12):2393-2403 [OPEN ACCESS]
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Ma, X; Rousseau, V; Sun, H; Lantuejoul, S; Filipits, M; Pirker, R; Popper, H; Mendiboure, J; Vataire, AL; Le Chevalier, T; Soria, JC; Brambilla, E; Dunant, A; Hainaut, P; IALT-Bio working group Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer.
Mol Oncol. 2014; 8(3):555-564 [OPEN ACCESS]
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Morisaki, T; Müller, WG; Golob, N; Mazza, D; McNally, JG Single-molecule analysis of transcription factor binding at transcription sites in live cells.
NAT COMMUN. 2014; 5: 4456-4456. [OPEN ACCESS]
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Rao, S; Tortola, L; Perlot, T; Wirnsberger, G; Novatchkova, M; Nitsch, R; Sykacek, P; Frank, L; Schramek, D; Komnenovic, V; Sigl, V; Aumayr, K; Schmauss, G; Fellner, N; Handschuh, S; Glösmann, M; Pasierbek, P; Schlederer, M; Resch, GP; Ma, Y; Yang, H; Popper, H; Kenner, L; Kroemer, G; Penninger, JM A dual role for autophagy in a murine model of lung cancer.
Nat Commun. 2014; 5(5):3056-3056 [OPEN ACCESS]
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Ress, AL; Stiegelbauer, V; Schwarzenbacher, D; Deutsch, A; Perakis, S; Ling, H; Ivan, C; Calin, GA; Rinner, B; Gerger, A; Pichler, M Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.
Oncotarget. 2014; 5(18):8492-8502 [OPEN ACCESS]
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2013

Gottschalk, B; Klein, A Restoration of wild-type p53 in drug-resistant mouse breast cancer cells leads to differential gene expression, but is not sufficient to overcome the malignant phenotype.
Mol Cell Biochem. 2013; 379(1-2): 213-227.
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Heitzer, E; Lax, S; Lafer, I; Müller, SM; Pristauz, G; Ulz, P; Jahn, S; Högenauer, C; Petru, E; Speicher, MR; Geigl, JB Multiplex genetic cancer testing identifies pathogenic mutations in TP53 and CDH1 in a patient with bilateral breast and endometrial adenocarcinoma.
BMC Med Genet. 2013; 14(1):129-129 (- Case Report) [OPEN ACCESS]
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Houben, R; Dreher, C; Angermeyer, S; Borst, A; Utikal, J; Haferkamp, S; Peitsch, WK; Schrama, D; Hesbacher, S Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens.
J Invest Dermatol. 2013; 133(10):2453-2460 [OPEN ACCESS]
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Lohberger, B; Rinner, B; Stuendl, N; Kaltenegger, H; Steinecker-Frohnwieser, B; Bernhart, E; Bonyadi Rad, E; Weinberg, AM; Leithner, A; Bauer, R; Kretschmer, N Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.
PLoS One. 2013; 8(6):e66300-e66300 [OPEN ACCESS]
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Schupp, M; Chen, F; Briggs, ER; Rao, S; Pelzmann, HJ; Pessentheiner, AR; Bogner-Strauss, JG; Lazar, MA; Baldwin, D; Prokesch, A Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues.
BMC Genomics. 2013; 14(11):758-758 [OPEN ACCESS]
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2012

Rinner, B; Gallè, B; Trajanoski, S; Fischer, C; Hatz, M; Maierhofer, T; Michelitsch, G; Moinfar, F; Stelzer, I; Pfragner, R; Guelly, C Molecular evidence for the bi-clonal origin of neuroendocrine tumor derived metastases.
BMC Genomics. 2012; 13(6):594-594 [OPEN ACCESS]
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Schulz, E; Valentin, A; Ulz, P; Beham-Schmid, C; Lind, K; Rupp, V; Lackner, H; Wölfler, A; Zebisch, A; Olipitz, W; Geigl, J; Berghold, A; Speicher, MR; Sill, H Germline mutations in the DNA damage response genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy related myeloid neoplasms.
J Med Genet. 2012; 49(7):422-428
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Szkandera, J; Absenger, G; Dandachi, N; Regitnig, P; Lax, S; Stotz, M; Samonigg, H; Renner, W; Gerger, A Analysis of functional germline polymorphisms for prediction of response to anthracycline-based neoadjuvant chemotherapy in breast cancer.
Mol Genet Genomics. 2012; 287(9):755-764
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2011

Houben, R; Hesbacher, S; Schmid, CP; Kauczok, CS; Flohr, U; Haferkamp, S; Müller, CS; Schrama, D; Wischhusen, J; Becker, JC High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays.
PLoS One. 2011; 6(7):e22096-e22096 [OPEN ACCESS]
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Langner, C Non-serrated precursor lesions of colorectal tumours.
Pathologe. 2011; 32 Suppl 2(1):206-210
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Morselli, E; Shen, S; Ruckenstuhl, C; Bauer, MA; Mariño, G; Galluzzi, L; Criollo, A; Michaud, M; Maiuri, MC; Chano, T; Madeo, F; Kroemer, G p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.
Cell Cycle. 2011; 10(16):2763-2769 [OPEN ACCESS]
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Sperka, T; Song, Z; Morita, Y; Nalapareddy, K; Guachalla, LM; Lechel, A; Begus-Nahrmann, Y; Burkhalter, MD; Mach, M; Schlaudraff, F; Liss, B; Ju, Z; Speicher, MR; Rudolph, KL Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction.
Nat Cell Biol. 2011; 14(1):73-79
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2010

Voortman, J; Goto, A; Mendiboure, J; Sohn, JJ; Schetter, AJ; Saito, M; Dunant, A; Pham, TC; Petrini, I; Lee, A; Khan, MA; Hainaut, P; Pignon, JP; Brambilla, E; Popper, HH; Filipits, M; Harris, CC; Giaccone, G MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non-Small Cell Lung Carcinoma.
Cancer Res. 2010; 70(21): 8288-8298. [OPEN ACCESS]
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2009

Schwarzbraun, T; Obenauf, A; Langmann, A; Gruber-Sedlmayr, U; Wagner, K; Speicher, M; Kroisel, P Predictive diagnosis of the cancer prone Li-Fraumeni syndrome by accident: new challenges through whole genome array testing.
J Med Genet. 2009; 46(5): 341-344. (- Case Report) [OPEN ACCESS]
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2008

Bohlig, L; Metzger, R; Rother, K; Till, H; Engeland, K The CCN3 gene coding for an extracellular adhesion-related protein is transcriptionally activated by the p53 tumor suppressor
Cell Cycle. 2008; 7(9):1254-1261 [OPEN ACCESS]
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2006

Goel, A; Fuerst, F; Hotchkiss, E; Boland, CR Selenomethionine induces p53 mediated cell cycle arrest and apoptosis in human colon cancer cells.
Cancer Biol Ther. 2006; 5(5):529-535 [OPEN ACCESS]
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2004

Zigeuner, R; Ratschek, M; Rehak, P; Schips, L; Langner, C Value of p53 as a prognostic marker in histologic subtypes of renal cell carcinoma: a systematic analysis of primary and metastatic tumor tissue.
UROLOGY. 2004; 63(4): 651-655.
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2001

Reles, A; Wen, WH; Schmider, A; Gee, C; Runnebaum, IB; Kilian, U; Jones, LA; El-Naggar, A; Minguillon, C; Schönborn, I; Reich, O; Kreienberg, R; Lichtenegger, W; Press, MF Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer.
Clin Cancer Res. 2001; 7(10):2984-2997 [OPEN ACCESS]
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Seidl, H; Kreimer-Erlacher, H; Bäck, B; Soyer, HP; Höfler, G; Kerl, H; Wolf, P Ultraviolet exposure as the main initiator of p53 mutations in basal cell carcinomas from psoralen and ultraviolet A-treated patients with psoriasis.
J Invest Dermatol. 2001; 117(2):365-370 [OPEN ACCESS]
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1997

Egle, A; Villunger, A; Marschitz, I; Kos, M; Hittmair, A; Lukas, P; Grünewald, K; Greil, R Expression of Apo-1/Fas (CD95), Bcl-2, Bax and Bcl-x in myeloma cell lines: relationship between responsiveness to anti-Fas mab and p53 functional status.
Br J Haematol. 1997; 97(2): 418-428.
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1994

Kovar, H; Zoubek, A; Pfleiderer, C; Jug, G; Auinger, A; Aryee, D; Ambros, PF; Salzer-Kuntschik, M; Amann, G; Windhager, R The EWS gene rearrangement in Ewing tumors: key to the disease
Klin Padiatr. 1994; 206(4): 196-200.
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