Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: TUMOR CELLS, CULTURED - , . Treffer: 254

2021

Grbčić, P; Eichmann, TO; Kraljević, Pavelić, S; Sedić, M The Sphingosine Kinase 2 Inhibitor ABC294640 Restores the Sensitivity of BRAFV600E Mutant Colon Cancer Cells to Vemurafenib by Reducing AKT-Mediated Expression of Nucleophosmin and Translationally-Controlled Tumour Protein.
Int J Mol Sci. 2021; 22(19): Doi: 10.3390/ijms221910767 [OPEN ACCESS]
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Martinez, RS; Salji, MJ; Rushworth, L; Ntala, C; Rodriguez, Blanco, G; Hedley, A; Clark, W; Peixoto, P; Hervouet, E; Renaude, E; Kung, SHY; Galbraith, LCA; Nixon, C; Lilla, S; MacKay, GM; Fazli, L; Gaughan, L; Sumpton, D; Gleave, ME; Zanivan, S; Blomme, A; Leung, HY SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer.
Cancer Res. 2021; 81(13):3664-3678 Doi: 10.1158/0008-5472.CAN-20-3694
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Nosella, ML; Tereshchenko, M; Pritišanac, I; Chong, PA; Toretsky, JA; Lee, HO; Forman-Kay, JD O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics.
J Am Chem Soc. 2021; 143(30):11520-11534 Doi: 10.1021/jacs.1c04194
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Schneider, R; Gademann, G; Ochel, HJ; Neumann, K; Jandrig, B; Hass, P; Walke, M; Schostak, M; Brunner, T; Christoph, F Functional and mutational analysis after radiation and cetuximab treatment on prostate carcinoma cell line DU145.
Radiat Oncol. 2021; 16(1): 137 Doi: 10.1186/s13014-021-01859-6 [OPEN ACCESS]
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Troitskaya, O; Novak, D; Nushtaeva, A; Savinkova, M; Varlamov, M; Ermakov, M; Richter, V; Koval, O EGFR Transgene Stimulates Spontaneous Formation of MCF7 Breast Cancer Cells Spheroids with Partly Loss of HER3 Receptor.
Int J Mol Sci. 2021; 22(23): Doi: 10.3390/ijms222312937 [OPEN ACCESS]
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2020

Arriga, R; Caratelli, S; Lanzilli, G; Ottaviani, A; Cenciarelli, C; Sconocchia, T; Spagnoli, GC; Iezzi, G; Roselli, M; Lauro, D; Coppola, A; Dotti, G; Ferrone, S; Sconocchia, G CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab.
Int J Cancer. 2020; 146(9):2531-2538 Doi: 10.1002/ijc.32618 [OPEN ACCESS]
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Dengler, MA; Teh, CE; Thijssen, R; Gangoda, L; Lan, P; Herold, MJ; Gray, DH; Kelly, GL; Roberts, AW; Adams, JM Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma.
Oncogene. 2020; 39(9):2009-2023 Doi: 10.1038/s41388-019-1122-x
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Obermüller, B; Singer, G; Kienesberger, B; Klymiuk, I; Sperl, D; Stadlbauer, V; Horvath, A; Miekisch, W; Gierschner, P; Grabherr, R; Gruber, HJ; Semeraro, MD; Till, H; Castellani, C The Effects of Prebiotic Supplementation with OMNi-LOGiC® FIBRE on Fecal Microbiome, Fecal Volatile Organic Compounds, and Gut Permeability in Murine Neuroblastoma-Induced Tumor-Associated Cachexia.
Nutrients. 2020; 12(7): Doi: 10.3390/nu12072029 [OPEN ACCESS]
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2019

Golob-Schwarzl, N; Wodlej, C; Kleinegger, F; Gogg-Kamerer, M; Birkl-Toeglhofer, AM; Petzold, J; Aigelsreiter, A; Thalhammer, M; Park, YN; Haybaeck, J Eukaryotic translation initiation factor 6 overexpression plays a major role in the translational control of gallbladder cancer.
J Cancer Res Clin Oncol. 2019; 145(11): 2699-2711. Doi: 10.1007/s00432-019-03030-x [OPEN ACCESS]
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Müller, M; Graf, R; Kashofer, K; Macher, S; Wölfler, A; Zebisch, A; Hrzenjak, A; Heitzer, E; Sill, H Detection of AML-specific TP53 mutations in bone marrow-derived mesenchymal stromal cells cultured under hypoxia conditions.
Ann Hematol. 2019; 98(8):2019-2020 Doi: 10.1007/s00277-019-03680-4 [OPEN ACCESS]
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2017

Grabiec, U; Hohmann, T; Hammer, N; Dehghani, F Organotypic Hippocampal Slice Cultures As a Model to Study Neuroprotection and Invasiveness of Tumor Cells.
J Vis Exp. 2017; 31(126): Doi: 10.3791/55359 [OPEN ACCESS]
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Karlsson, J; Kroneis, T; Jonasson, E; Larsson, E; Ståhlberg, A Transcriptomic Characterization of the Human Cell Cycle in Individual Unsynchronized Cells.
J Mol Biol. 2017; 429(24):3909-3924 Doi: 10.1016/j.jmb.2017.10.011
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Peschel, I; Podmirseg, SR; Taschler, M; Duyster, J; Götze, KS; Sill, H; Nachbaur, D; Jäkel, H; Hengst, L FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27Kip1 in acute myeloid leukemia.
Haematologica. 2017; 102(8):1378-1389 Doi: 10.3324/haematol.2016.160101 [OPEN ACCESS]
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Rashed, MH; Kanlikilicer, P; Rodriguez-Aguayo, C; Pichler, M; Bayraktar, R; Bayraktar, E; Ivan, C; Filant, J; Silva, A; Aslan, B; Denizli, M; Mitra, R; Ozpolat, B; Calin, GA; Sood, AK; Abd-Ellah, MF; Helal, GK; Berestein, GL Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget. 2017; 8(12):20145-20164 Doi: 10.18632/oncotarget.15525 [OPEN ACCESS]
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2016

Arriga, R; Caratelli, S; Coppola, A; Spagnoli, GC; Venditti, A; Amadori, S; Lanzilli, G; Lauro, D; Palomba, P; Sconocchia, T; Del Principe, MI; Maurillo, L; Buccisano, F; Capuani, B; Ferrone, S; Sconocchia, G Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.
Oncotarget. 2016; 7(2): 2070-2079. Doi: 10.18632/oncotarget.6529 [OPEN ACCESS]
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Höckendorf, U; Yabal, M; Herold, T; Munkhbaatar, E; Rott, S; Jilg, S; Kauschinger, J; Magnani, G; Reisinger, F; Heuser, M; Kreipe, H; Sotlar, K; Engleitner, T; Rad, R; Weichert, W; Peschel, C; Ruland, J; Heikenwalder, M; Spiekermann, K; Slotta-Huspenina, J; Groß, O; Jost, PJ RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.
Cancer Cell. 2016; 30(1):75-91 Doi: 10.1016/j.ccell.2016.06.002 [OPEN ACCESS]
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Rasoulzadeh, Z; Ghods, R; Kazemi, T; Mirzadegan, E; Ghaffari-Tabrizi-Wizsy, N; Rezania, S; Kazemnejad, S; Arefi, S; Ghasemi, J; Vafaei, S; Mahmoudi, AR; Zarnani, AH Placental Kisspeptins Differentially Modulate Vital Parameters of Estrogen Receptor-Positive and -Negative Breast Cancer Cells.
PLoS One. 2016; 11(4):e0153684-e0153684 Doi: 10.1371/journal.pone.0153684 [OPEN ACCESS]
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2015

Dehghan Esmatabadi, MJ; Farhangi, B; Safari, Z; Kazerooni, H; Shirzad, H; Zolghadr, F; Sadeghizadeh, M Dendrosomal curcumin inhibits metastatic potential of human SW480 colon cancer cells through Down-regulation of Claudin1, Zeb1 and Hef1-1 gene expression.
Asian Pac J Cancer Prev. 2015; 16(6):2473-2481 Doi: 10.7314/APJCP.2015.16.6.2473 [OPEN ACCESS]
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Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
Mol Cancer. 2015; 14(8):4-4 Doi: 10.1186/1476-4598-14-4 [OPEN ACCESS]
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Houben, R; Angermeyer, S; Haferkamp, S; Aue, A; Goebeler, M; Schrama, D; Hesbacher, S Characterization of functional domains in the Merkel cell polyoma virus Large T antigen.
Int J Cancer. 2015; 136(5):E290-E300 Doi: 10.1002/ijc.29200 [OPEN ACCESS]
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Leithner, K; Hrzenjak, A; Trötzmüller, M; Moustafa, T; Köfeler, HC; Wohlkoenig, C; Stacher, E; Lindenmann, J; Harris, AL; Olschewski, A; Olschewski, H PCK2 activation mediates an adaptive response to glucose depletion in lung cancer.
Oncogene. 2015; 34(8):1044-1050 Doi: 10.1038/onc.2014.47
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Schwarzenbacher, D; Stiegelbauer, V; Deutsch, A; Ress, AL; Aigelsreiter, A; Schauer, S; Wagner, K; Langsenlehner, T; Resel, M; Gerger, A; Ling, H; Ivan, C; Calin, GA; Hoefler, G; Rinner, B; Pichler, M Low spinophilin expression enhances aggressive biological behavior of breast cancer.
Oncotarget. 2015; 6(13):11191-11202 Doi: 10.18632/oncotarget.3586 [OPEN ACCESS]
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2014

Al-Assar, O; Demiciorglu, F; Lunardi, S; Gaspar-Carvalho, MM; McKenna, WG; Muschel, RM; Brunner, TB Contextual regulation of pancreatic cancer stem cell phenotype and radioresistance by pancreatic stellate cells.
Radiother Oncol. 2014; 111(2):243-51 Doi: 10.1016/j.radonc.2014.03.014
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Forster, T; Rausch, V; Zhang, Y; Isayev, O; Heilmann, K; Schoensiegel, F; Liu, L; Nessling, M; Richter, K; Labsch, S; Nwaeburu, CC; Mattern, J; Gladkich, J; Giese, N; Werner, J; Schemmer, P; Gross, W; Gebhard, MM; Gerhauser, C; Schaefer, M; Herr, I Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication.
Oncotarget. 2014; 5(6):1621-1634 Doi: 10.18632/oncotarget.1764 [OPEN ACCESS]
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Quan, P; Moinfar, F; Kufferath, I; Absenger, M; Kueznik, T; Denk, H; Zatloukal, K; Haybaeck, J Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling.
Anticancer Res. 2014; 34(6):2883-2897
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2013

Shimato, S; Anderson, LM; Asslaber, M; Bruce, JN; Canoll, P; Anderson, DE; Anderson, RC Inhibition of caveolin-1 restores myeloid cell function in human glioblastoma.
PLoS One. 2013; 8(10):e77397-e77397 Doi: 10.1371/journal.pone.0077397 [OPEN ACCESS]
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2012

Rohrl, C; Meisslitzer-Ruppitsch, C; Bittman, R; Li, ZG; Pabst, G; Prassl, R; Strobl, W; Neumuller, J; Ellinger, A; Pavelka, M; Stangl, H Combined Light and Electron Microscopy Using Diaminobenzidine Photooxidation to Monitor Trafficking of Lipids Derived from Lipoprotein Particles
CURR PHARM BIOTECHNO. 2012; 13(2): 331-340. Doi: 10.2174/138920112799095338 [OPEN ACCESS]
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Salnikov, AV; Liu, L; Platen, M; Gladkich, J; Salnikova, O; Ryschich, E; Mattern, J; Moldenhauer, G; Werner, J; Schemmer, P; Büchler, MW; Herr, I Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential.
PLoS One. 2012; 7(9):e46391-e46391 Doi: 10.1371/journal.pone.0046391 [OPEN ACCESS]
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2011

Hoffmann, K; Shibo, L; Xiao, Z; Longerich, T; Büchler, MW; Schemmer, P Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
Anticancer Res. 2011; 31(11):3883-3890
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Mayrhauser, U; Stiegler, P; Stadlbauer, V; Koestenbauer, S; Leber, B; Konrad, K; Iberer, F; Portugaller, RH; Tscheliessnigg, K Effect of hyperthermia on liver cell lines: important findings for thermal therapy in hepatocellular carcinoma.
Anticancer Res. 2011; 31(5):1583-1588
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Presneau, N; Shalaby, A; Ye, H; Pillay, N; Halai, D; Idowu, B; Tirabosco, R; Whitwell, D; Jacques, TS; Kindblom, LG; Brüderlein, S; Möller, P; Leithner, A; Liegl, B; Amary, FM; Athanasou, NN; Hogendoorn, PC; Mertens, F; Szuhai, K; Flanagan, AM Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study.
J Pathol. 2011; 223(3): 327-335. Doi: 10.1002/path.2816
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Shalaby, A; Presneau, N; Ye, H; Halai, D; Berisha, F; Idowu, B; Leithner, A; Liegl, B; Briggs, TR; Bacsi, K; Kindblom, LG; Athanasou, N; Amary, MF; Hogendoorn, PC; Tirabosco, R; Flanagan, AM The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target.
J Pathol. 2011; 223(3): 336-346. Doi: 10.1002/path.2818
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2010

Eberle, J; Spangler, B; Becker, JC; Heinemann, SH; Klein, CA; Kunz, M; Kuphal, S; Langer, P; Mauch, C; Meierjohann, S; Paschen, A; Schadendorf, D; Schartl, M; Schittek, B; Schonherr, R; Tuting, T; Zigrino, P; Bosserhoff, AK Multicentre study on standardisation of melanoma cell culture - an initiative of the German Melanoma Research Network
PIGM CELL MELANOMA R. 2010; 23(2): 296-298. Doi: 10.1111/j.1755-148X.2010.00684.x [OPEN ACCESS]
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Erdman, SE; Rao, VP; Olipitz, W; Taylor, CL; Jackson, EA; Levkovich, T; Lee, CW; Horwitz, BH; Fox, JG; Ge, ZM; Poutahidis, T Unifying roles for regulatory T cells and inflammation in cancer.
Int J Cancer. 2010; 126(7):1651-1665 Doi: 10.1002/ijc.24923 [OPEN ACCESS]
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Hoffmann, K; Franz, C; Xiao, Z; Mohr, E; Serba, S; Büchler, MW; Schemmer, P Sorafenib modulates the gene expression of multi-drug resistance mediating ATP-binding cassette proteins in experimental hepatocellular carcinoma.
Anticancer Res. 2010; 30(11):4503-4508
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Kopp, KLM; Kauczok, CS; Lauenborg, B; Krejsgaard, T; Eriksen, KW; Zhang, Q; Wasik, MA; Geisler, C; Ralfkiaer, E; Becker, JC; Odum, N; Woetmann, A COX-2-dependent PGE(2) acts as a growth factor in mycosis fungoides (MF)
LEUKEMIA. 2010; 24(6): 1179-1185. Doi: 10.1038/leu.2010.66 [OPEN ACCESS]
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Müller-Tidow, C; Klein, HU; Hascher, A; Isken, F; Tickenbrock, L; Thoennissen, N; Agrawal-Singh, S; Tschanter, P; Disselhoff, C; Wang, Y; Becker, A; Thiede, C; Ehninger, G; zur Stadt, U; Koschmieder, S; Seidl, M; Müller, FU; Schmitz, W; Schlenke, P; McClelland, M; Berdel, WE; Dugas, M; Serve, H; Study Alliance Leukemia Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.
Blood. 2010; 116(18): 3564-3571. Doi: 10.1182/blood-2009-09-240978 [OPEN ACCESS]
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Soriţău, O; Tomuleasa, CI; Páll, E; Virág, P; Fischer-Fodor, E; Foris, V; Barbos, O; Tatomir, C; Kacsó, G; Irimie, A Enhanced chemoresistance and tumor sphere formation as a laboratory model for peritoneal micrometastasis in epithelial ovarian cancer.
Rom J Morphol Embryol. 2010; 51(2):259-264 [OPEN ACCESS]
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Tomuleasa, C; Soritau, O; Rus-Ciuca, D; Pop, T; Todea, D; Mosteanu, O; Pintea, B; Foris, V; Susman, S; Kacsó, G; Irimie, A Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma.
J Gastrointestin Liver Dis. 2010; 19(1):61-67 [OPEN ACCESS]
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2009

Pfragner, R; Behmel, A; Höger, H; Beham, A; Ingolic, E; Stelzer, I; Svejda, B; Moser, VA; Obenauf, AC; Siegl, V; Haas, O; Niederle, B Establishment and characterization of three novel cell lines - P-STS, L-STS, H-STS - derived from a human metastatic midgut carcinoid.
ANTICANCER RES. 2009; 29(6): 1951-1961. [OPEN ACCESS]
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Reim, F; Dombrowski, Y; Ritter, C; Buttmann, M; Hausler, S; Ossadnik, M; Krockenberger, M; Beier, D; Beier, CP; Dietl, J; Becker, JC; Honig, A; Wischhusen, J Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells.
Cancer Res. 2009; 69(20):8058-8066 Doi: 10.1158/0008-5472.CAN-09-0834 [OPEN ACCESS]
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2008

Gil, Z; Kelly, KJ; Brader, P; Shah, JP; Fong, Y; Wong, RJ Utility of a herpes oncolytic virus for the detection of neural invasion by cancer.
Neoplasia. 2008; 10(4):347-353 Doi: 10.1593/neo.07981 [OPEN ACCESS]
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Kidd, M; Schally, AV; Pfragner, R; Malfertheiner, MV; Modlin, IM Inhibition of proliferation of small intestinal and bronchopulmonary neuroendocrine cell lines by using peptide analogs targeting receptors.
Cancer. 2008; 112(6): 1404-1414. Doi: 10.1002/cncr.23303 [OPEN ACCESS]
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Ochsenreither, S; Fusi, A; Busse, A; Nagorsen, D; Schrama, D; Becker, J; Thiel, E; Keilholz, U Relative quantification of TCR Vbeta-chain families by real time PCR for identification of clonal T-cell populations.
J Transl Med. 2008; 6(1):34-34 Doi: 10.1186/1479-5876-6-34 [OPEN ACCESS]
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Sauermann, M; Sahin, O; Sültmann, H; Hahne, F; Blaszkiewicz, S; Majety, M; Zatloukal, K; Füzesi, L; Poustka, A; Wiemann, S; Arlt, D Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells.
Oncogene. 2008; 27(9):1320-1326 Doi: 10.1038/sj.onc.1210743 [OPEN ACCESS]
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Skoda, C; Erovic, BM; Wachek, V; Vormittag, L; Wrba, F; Martinek, H; Heiduschka, G; Kloimstein, P; Selzer, E; Thurnher, D Down-regulation of Mcl-1 with antisense technology alters the effect of various cytotoxic agents used in treatment of squamous cell carcinoma of the head and neck.
Oncol Rep. 2008; 19(6):1499-1503
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Stadler, G; Wieser, M; Streubel, B; Stift, A; Friedl, J; Gnant, M; Niederle, B; Beham, A; Katinger, H; Pfragner, R; Grillari, J; Voglauer, R Low telomerase activity: possible role in the progression of human medullary thyroid carcinoma.
Eur J Cancer. 2008; 44(6): 866-875. Doi: 10.1016/j.ejca.2007.12.014 [OPEN ACCESS]
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2007

Gattenloehner, S; Chuvpilo, S; Langebrake, C; Reinhardt, D; Muller-Hermelink, HK; Serfling, E; Vincent, A; Marx, A Novel RUNX1 isoforms determine the fate of acute myeloid leukemia cells by controlling CD56 expression.
Blood. 2007; 110(6):2027-2033 Doi: 10.1182/blood-2007-02-074203 [OPEN ACCESS]
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Haas, HS; Pfragner, R; Siegl, V; Ingolic, E; Heintz, E; Schraml, E; Schauenstein, K The non-competitive metabotropic glutamate receptor-1 antagonist CPCCOEt inhibits the in vitro growth of human melanoma.
Oncol Rep. 2007; 17(6): 1399-1404. Doi: 10.3892/or.17.6.1399
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Kidd, M; Modlin, IM; Pfragner, R; Eick, GN; Champaneria, MC; Chan, AK; Camp, RL; Mane, SM Small bowel carcinoid (enterochromaffin cell) neoplasia exhibits transforming growth factor-beta1-mediated regulatory abnormalities including up-regulation of C-Myc and MTA1.
CANCER. 2007; 109(12): 2420-2431. Doi: 10.1002/cncr.22725 [OPEN ACCESS]
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