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Publikationen

Suchbegriffe: TRANSFECTION - , . Treffer: 176

2017

Bayraktar, R; Pichler, M; Kanlikilicer, P; Ivan, C; Bayraktar, E; Kahraman, N; Aslan, B; Oguztuzun, S; Ulasli, M; Arslan, A; Calin, G; Lopez-Berestein, G; Ozpolat, B MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase.
Oncotarget. 2017; 8(7): 11641-11658. Doi: 10.18632/oncotarget.14264 [OPEN ACCESS]
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Hamilton, EMC; Bertini, E; Kalaydjieva, L; Morar, B; Dojčáková, D; Liu, J; Vanderver, A; Curiel, J; Persoon, CM; Diodato, D; Pinelli, L; van der Meij, NL; Plecko, B; Blaser, S; Wolf, NI; Waisfisz, Q; Abbink, TEM; van der Knaap, MS; Recessive H-ABC Research Group UFM1 founder mutation in the Roma population causes recessive variant of H-ABC.
Neurology. 2017; 89(17):1821-1828 Doi: 10.1212/WNL.0000000000004578 [OPEN ACCESS]
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Longtine, MS; Cvitic, S; Colvin, BN; Chen, B; Desoye, G; Nelson, DM Calcitriol regulates immune genes CD14 and CD180 to modulate LPS responses in human trophoblasts.
Reproduction. 2017; 154(6):735-744 Doi: 10.1530/REP-17-0183 [OPEN ACCESS]
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2016

Fan, P; Liu, L; Yin, Y; Zhao, Z; Zhang, Y; Amponsah, PS; Xiao, X; Bauer, N; Abukiwan, A; Nwaeburu, CC; Gladkich, J; Gao, C; Schemmer, P; Gross, W; Herr, I MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer.
Cancer Lett. 2016; 373(1):130-137 Doi: 10.1016/j.canlet.2016.01.038
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Gomez-Escobar, N; Almobadel, N; Alzahrani, O; Feichtinger, J; Planells-Palop, V; Alshehri, Z; Thallinger, GG; Wakeman, JA; McFarlane, RJ Translin and Trax differentially regulate telomere-associated transcript homeostasis.
Oncotarget. 2016; 7(23): 33809-33820. Doi: 10.18632/oncotarget.9278 [OPEN ACCESS]
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Kanlikilicer, P; Rashed, MH; Bayraktar, R; Mitra, R; Ivan, C; Aslan, B; Zhang, X; Filant, J; Silva, AM; Rodriguez-Aguayo, C; Bayraktar, E; Pichler, M; Ozpolat, B; Calin, GA; Sood, AK; Lopez-Berestein, G Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells.
Cancer Res. 2016; 76(24):7194-7207 Doi: 10.1158/0008-5472.CAN-16-0714 [OPEN ACCESS]
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Shahbazi, E; Moradi, S; Nemati, S; Satarian, L; Basiri, M; Gourabi, H; Zare Mehrjardi, N; Günther, P; Lampert, A; Händler, K; Hatay, FF; Schmidt, D; Molcanyi, M; Hescheler, J; Schultze, JL; Saric, T; Baharvand, H Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor.
Stem Cell Reports. 2016; 6(4):539-551 Doi: 10.1016/j.stemcr.2016.02.013 [OPEN ACCESS]
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Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165 Doi: 10.1152/ajpgi.00143.2015 [OPEN ACCESS]
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Tuller, F; Holzer, H; Schanda, K; Aboulenein-Djamshidian, F; Höftberger, R; Khalil, M; Seifert-Held, T; Leutmezer, F; Berger, T; Reindl, M Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders.
J Neuroinflammation. 2016; 13(1):176-176 Doi: 10.1186/s12974-016-0642-3 [OPEN ACCESS]
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Vogl, F; Humpolickova, J; Amaro, M; Koller, D; Kofeler, H; Zenzmaier, E; Hof, M; Hermetter, A Role of protein kinase C delta in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages
BBA-MOL CELL BIOL L. 2016; 1861(4): 320-330. Doi: 10.1016/j.bbalip.2015.12.009
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Winnik, S; Gaul, DS; Siciliani, G; Lohmann, C; Pasterk, L; Calatayud, N; Weber, J; Eriksson, U; Auwerx, J; van Tits, LJ; Lüscher, TF; Matter, CM Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2.
Basic Res Cardiol. 2016; 111(3):33-33 Doi: 10.1007/s00395-016-0552-7 [OPEN ACCESS]
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2015

Bagdonaite, I; Wandall, HH; Litvinov, IV; Nastasi, C; Becker, JC; Dabelsteen, S; Geisler, C; Bonefeld, CM; Zhang, Q; Wasik, MA; Zhou, Y; Sasseville, D; Ødum, N; Woetmann, A Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients.
Oncotarget. 2015; 6(16):14374-14384 Doi: 10.18632/oncotarget.3720 [OPEN ACCESS]
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Berghold, VM; Gauster, M; Hemmings, DG; Moser, G; Kremshofer, J; Siwetz, M; Sundl, M; Huppertz, B Phospholipid scramblase 1 (PLSCR1) in villous trophoblast of the human placenta.
Histochem Cell Biol. 2015; 143(4):381-396 Doi: 10.1007/s00418-014-1294-y
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Laszlo, V; Hoda, MA; Garay, T; Pirker, C; Ghanim, B; Klikovits, T; Dong, YW; Rozsas, A; Kenessey, I; Szirtes, I; Grusch, M; Jakopovic, M; Samarzija, M; Brcic, L; Kern, I; Rozman, A; Popper, H; Zöchbauer-Müller, S; Heller, G; Altenberger, C; Ziegler, B; Klepetko, W; Berger, W; Dome, B; Hegedus, B Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
J Pathol. 2015; 237(2):203-214 Doi: 10.1002/path.4567
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Nairz, M; Schroll, A; Haschka, D; Dichtl, S; Sonnweber, T; Theurl, I; Theurl, M; Lindner, E; Demetz, E; Aßhoff, M; Bellmann-Weiler, R; Müller, R; Gerner, RR; Moschen, AR; Baumgartner, N; Moser, PL; Talasz, H; Tilg, H; Fang, FC; Weiss, G Lipocalin-2 ensures host defense against Salmonella Typhimurium by controlling macrophage iron homeostasis and immune response.
Eur J Immunol. 2015; 45(11):3073-3086 Doi: 10.1002/eji.201545569 [OPEN ACCESS]
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Reimann, S; Fink, L; Wilhelm, J; Hoffmann, J; Bednorz, M; Seimetz, M; Dessureault, I; Troesser, R; Ghanim, B; Klepetko, W; Seeger, W; Weissmann, N; Kwapiszewska, G Increased S100A4 expression in the vasculature of human COPD lungs and murine model of smoke-induced emphysema.
Respir Res. 2015; 16(10):127-127 Doi: 10.1186/s12931-015-0284-5 [OPEN ACCESS]
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Weilner, S; Skalicky, S; Salzer, B; Keider, V; Wagner, M; Hildner, F; Gabriel, C; Dovjak, P; Pietschmann, P; Grillari-Voglauer, R; Grillari, J; Hackl, M Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation.
Bone. 2015; 79(136):43-51 Doi: 10.1016/j.bone.2015.05.027 [OPEN ACCESS]
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Zhao, H; Davies, TJ; Ning, J; Chang, Y; Sachamitr, P; Sattler, S; Fairchild, PJ; Huang, FP A highly optimized protocol for reprogramming cancer cells to pluripotency using nonviral plasmid vectors.
Cell Reprogram. 2015; 17(1): 7-18. Doi: 10.1089/cell.2014.0046 [OPEN ACCESS]
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2014

Bast, A; Krause, K; Schmidt, IH; Pudla, M; Brakopp, S; Hopf, V; Breitbach, K; Steinmetz, I Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophages.
PLoS Pathog. 2014; 10(3): e1003986-e1003986. Doi: 10.1371/journal.ppat.1003986 [OPEN ACCESS]
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Bernhart, E; Damm, S; Heffeter, P; Wintersperger, A; Asslaber, M; Frank, S; Hammer, A; Strohmaier, H; DeVaney, T; Mrfka, M; Eder, H; Windpassinger, C; Ireson, CR; Mischel, PS; Berger, W; Sattler, W Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.
Neuro Oncol. 2014; 16(7):933-945 Doi: 10.1093/neuonc/not303 [OPEN ACCESS]
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Folci, A; Mapelli, L; Sassone, J; Prestori, F; D'Angelo, E; Bassani, S; Passafaro, M Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons.
J Neurosci. 2014; 34(27): 9088-9095. Doi: 10.1523/JNEUROSCI.0303-14.2014 [OPEN ACCESS]
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Huang, J; Huffman, JE; Yamkauchi, M; Trompet, S; Asselbergs, FW; Sabater-Lleal, M; Tregouet, DA; Chen, WM; Smith, NL; Kleber, ME; Shin, SY; Becker, DM; Tang, WH; Dehghan, A; Johnson, AD; Truong, V; Folkersen, L; Yang, Q; Oudot-Mellkah, T; Buckley, BM; Moore, JH; Williams, FMK; Campbell, H; Silbernagel, G; Vitart, V; Rudan, I; Tofler, GH; Navis, GJ; DeStefano, A; Wright, AF; Chen, MH; de Craen, AJM; Worrall, BB; Rudnicka, AR; Rumley, A; Bookman, EB; Psaty, BM; Chen, F; Keene, KL; Franco, OH; Bohm, BO; Uitterlinden, AG; Carter, AM; Jukema, JW; Sattar, N; Bis, JC; Ikram, MA; Sale, MM; McKnight, B; Fornage, M; Ford, I; Taylor, K; Slagboom, PE; McArdle, WL; Hsu, FC; Franco-Cereceda, A; Goodall, AH; Yanek, LR; Furie, KL; Cushman, M; Hofman, A; Witteman, JCM; Folsom, AR; Basu, S; Matijevic, N; van Gilst, WH; Wilson, JF; Westendorp, RGJ; Kathiresan, S; Reilly, MP; Tracy, RP; Polasek, O; Winkelmann, BR; Grant, PJ; Hillege, HL; Cambien, F; Stott, DJ; Lowe, GD; Spector, TD; Meigs, JB; Marz, W; Eriksson, P; Becker, LC; Morange, PE; Soranzo, N; Williams, SM; Hayward, C; van der Harst, P; Hamsten, A; Lowenstein, CJ; Strachan, DP; O'Donnell, CJ; Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2.
ARTERIOSCLER THROMB VASC BIOL. 2014; 34(5): 1093-1101. Doi: 10.1161/ATVBAHA.113.302088 [OPEN ACCESS]
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Mills, PB; Camuzeaux, SS; Footitt, EJ; Mills, KA; Gissen, P; Fisher, L; Das, KB; Varadkar, SM; Zuberi, S; McWilliam, R; Stödberg, T; Plecko, B; Baumgartner, MR; Maier, O; Calvert, S; Riney, K; Wolf, NI; Livingston, JH; Bala, P; Morel, CF; Feillet, F; Raimondi, F; Del Giudice, E; Chong, WK; Pitt, M; Clayton, PT Epilepsy due to PNPO mutations: genotype, environment and treatment affect presentation and outcome.
Brain. 2014; 137(Pt 5): 1350-1360. Doi: 10.1093/brain/awu051 [OPEN ACCESS]
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Pichler, M; Ress, AL; Winter, E; Stiegelbauer, V; Karbiener, M; Schwarzenbacher, D; Scheideler, M; Ivan, C; Jahn, SW; Kiesslich, T; Gerger, A; Bauernhofer, T; Calin, GA; Hoefler, G MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients.
Br J Cancer. 2014; 110(6):1614-1621 Doi: 10.1038/bjc.2014.51 [OPEN ACCESS]
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Ress, AL; Stiegelbauer, V; Schwarzenbacher, D; Deutsch, A; Perakis, S; Ling, H; Ivan, C; Calin, GA; Rinner, B; Gerger, A; Pichler, M Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.
Oncotarget. 2014; 5(18):8492-8502 Doi: 10.18632/oncotarget.2329 [OPEN ACCESS]
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Veith, C; Zakrzewicz, D; Dahal, BK; Bálint, Z; Murmann, K; Wygrecka, M; Seeger, W; Schermuly, RT; Weissmann, N; Kwapiszewska, G Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.
Thromb Haemost. 2014; 112(6):1288-1303 Doi: 10.1160/TH13-12-1031
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2013

Derler, I; Schindl, R; Fritsch, R; Heftberger, P; Riedl, MC; Begg, M; House, D; Romanin, C The action of selective CRAC channel blockers is affected by the Orai pore geometry.
Cell Calcium. 2013; 53(2): 139-151. Doi: 10.1016/j.ceca.2012.11.005 [OPEN ACCESS]
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König, S; Browne, S; Doleschal, B; Schernthaner, M; Poteser, M; Mächler, H; Wittchow, E; Braune, M; Muik, M; Romanin, C; Groschner, K Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.
Am J Physiol Heart Circ Physiol. 2013; 305(11):H1646-H1657 Doi: 10.1152/ajpheart.00365.2013 [OPEN ACCESS]
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Lakshminarayanan, A; Ravi, VK; Tatineni, R; Rajesh, YB; Maingi, V; Vasu, KS; Madhusudhan, N; Maiti, PK; Sood, AK; Das, S; Jayaraman, N Efficient dendrimer-DNA complexation and gene delivery vector properties of nitrogen-core poly(propyl ether imine) dendrimer in mammalian cells.
Bioconjug Chem. 2013; 24(9): 1612-1623. Doi: 10.1021/bc400247w
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Merkel, OM; Marsh, LM; Garn, H; Kissel, T Flow cytometry-based cell type-specific assessment of target regulation by pulmonary siRNA delivery.
Methods Mol Biol. 2013; 948(3):263-273 Doi: 10.1007/978-1-62703-140-0_18 [OPEN ACCESS]
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Robert, J; Lehner, M; Frank, S; Perisa, D; von Eckardstein, A; Rohrer, L Interleukin 6 stimulates endothelial binding and transport of high-density lipoprotein through induction of endothelial lipase.
Arterioscler Thromb Vasc Biol. 2013; 33(12):2699-2706 Doi: 10.1161/ATVBAHA.113.301363 [OPEN ACCESS]
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Rommer, A; Steinleitner, K; Hackl, H; Schneckenleithner, C; Engelmann, M; Scheideler, M; Vlatkovic, I; Kralovics, R; Cerny-Reiterer, S; Valent, P; Sill, H; Wieser, R Overexpression of primary microRNA 221/222 in acute myeloid leukemia.
BMC Cancer. 2013; 13(8):364-364 Doi: 10.1186/1471-2407-13-364 [OPEN ACCESS]
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Walte, A; Rüben, K; Birner-Gruenberger, R; Preisinger, C; Bamberg-Lemper, S; Hilz, N; Bracher, F; Becker, W Mechanism of dual specificity kinase activity of DYRK1A.
FEBS J. 2013; 280(18):4495-4511 Doi: 10.1111/febs.12411 [OPEN ACCESS]
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2012

Bassani, S; Cingolani, LA; Valnegri, P; Folci, A; Zapata, J; Gianfelice, A; Sala, C; Goda, Y; Passafaro, M The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking.
Neuron. 2012; 73(6): 1143-1158. Doi: 10.1016/j.neuron.2012.01.021 [OPEN ACCESS]
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Brkić, L; Riederer, M; Graier, WF; Malli, R; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on cyclooxygenase (COX)-2 expression in endothelial cells.
Atherosclerosis. 2012; 224(2):348-354 Doi: 10.1016/j.atherosclerosis.2012.07.038 [OPEN ACCESS]
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Demetz, E; Tancevski, I; Duwensee, K; Stanzl, U; Huber, E; Heim, C; Handle, F; Theurl, M; Schroll, A; Tailleux, A; Dietrich, H; Patsch, JR; Eller, P; Ritsch, A Inhibition of hepatic scavenger receptor-class B type I by RNA interference decreases atherosclerosis in rabbits.
Atherosclerosis. 2012; 222(2):360-366 Doi: 10.1016/j.atherosclerosis.2012.03.012 [OPEN ACCESS]
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Jayawardena, TM; Egemnazarov, B; Finch, EA; Zhang, L; Payne, JA; Pandya, K; Zhang, Z; Rosenberg, P; Mirotsou, M; Dzau, VJ MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes.
Circ Res. 2012; 110(11):1465-1473 Doi: 10.1161/CIRCRESAHA.112.269035 [OPEN ACCESS]
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Kwapiszewska, G; Markart, P; Dahal, BK; Kojonazarov, B; Marsh, LM; Schermuly, RT; Taube, C; Meinhardt, A; Ghofrani, HA; Steinhoff, M; Seeger, W; Preissner, KT; Olschewski, A; Weissmann, N; Wygrecka, M PAR-2 inhibition reverses experimental pulmonary hypertension.
Circ Res. 2012; 110(9):1179-1191 Doi: 10.1161/CIRCRESAHA.111.257568 [OPEN ACCESS]
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Löffler, T; Flunkert, S; Taub, N; Schofield, EL; Ward, MA; Windisch, M; Hutter-Paier, B Stable mutated tau441 transfected SH-SY5Y cells as screening tool for Alzheimer's disease drug candidates.
J Mol Neurosci. 2012; 47(1): 192-203. Doi: 10.1007/s12031-012-9716-6 [OPEN ACCESS]
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Riederer, M; Köfeler, H; Lechleitner, M; Tritscher, M; Frank, S Impact of endothelial lipase on cellular lipid composition.
Biochim Biophys Acta. 2012; 1821(7):1003-1011 Doi: 10.1016/j.bbalip.2012.03.006 [OPEN ACCESS]
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van Baalen, A; Häusler, M; Plecko-Startinig, B; Strautmanis, J; Vlaho, S; Gebhardt, B; Rohr, A; Abicht, A; Kluger, G; Stephani, U; Probst, C; Vincent, A; Bien, CG Febrile infection-related epilepsy syndrome without detectable autoantibodies and response to immunotherapy: a case series and discussion of epileptogenesis in FIRES.
Neuropediatrics. 2012; 43(4):209-216 Doi: 10.1055/s-0032-1323848
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Van Der Werf, CS; Wabbersen, TD; Hsiao, NH; Paredes, J; Etchevers, HC; Kroisel, PM; Tibboel, D; Babarit, C; Schreiber, RA; Hoffenberg, EJ; Vekemans, M; Zeder, SL; Ceccherini, I; Lyonnet, S; Ribeiro, AS; Seruca, R; Te Meerman, GJ; van Ijzendoorn, SC; Shepherd, IT; Verheij, JB; Hofstra, RM CLMP is required for intestinal development, and loss-of-function mutations cause congenital short-bowel syndrome.
Gastroenterology. 2012; 142(3):453-462 Doi: 10.1053/j.gastro.2011.11.038
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2011

Baranyi, U; Gattringer, M; Boehm, A; Marth, K; Focke-Tejkl, M; Bohle, B; Blatt, K; Valent, P; Valenta, R; Wekerle, T Expression of a major plant allergen as membrane-anchored and secreted protein in human cells with preserved T cell and B cell epitopes.
Int Arch Allergy Immunol. 2011; 156(3):259-266 Doi: 10.1159/000323733
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Carmona-Gutiérrez, D; Bauer, MA; Ring, J; Knauer, H; Eisenberg, T; Büttner, S; Ruckenstuhl, C; Reisenbichler, A; Magnes, C; Rechberger, GN; Birner-Gruenberger, R; Jungwirth, H; Fröhlich, KU; Sinner, F; Kroemer, G; Madeo, F The propeptide of yeast cathepsin D inhibits programmed necrosis.
Cell Death Dis. 2011; 2(16):e161-e161 Doi: 10.1038/cddis.2011.43 [OPEN ACCESS]
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Fiorotto, R; Scirpo, R; Trauner, M; Fabris, L; Hoque, R; Spirli, C; Strazzabosco, M Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
Gastroenterology. 2011; 141(4): 1508.e1- 1508.e5 Doi: 10.1053/j.gastro.2011.06.052 [OPEN ACCESS]
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Knöll, R; Linke, WA; Zou, P; Miocic, S; Kostin, S; Buyandelger, B; Ku, CH; Neef, S; Bug, M; Schäfer, K; Knöll, G; Felkin, LE; Wessels, J; Toischer, K; Hagn, F; Kessler, H; Didié, M; Quentin, T; Maier, LS; Teucher, N; Unsöld, B; Schmidt, A; Birks, EJ; Gunkel, S; Lang, P; Granzier, H; Zimmermann, WH; Field, LJ; Faulkner, G; Dobbelstein, M; Barton, PJ; Sattler, M; Wilmanns, M; Chien, KR Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart.
Circ Res. 2011; 109(7):758-769 Doi: 10.1161/CIRCRESAHA.111.245787 [OPEN ACCESS]
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Mahajan, V; Klingstedt, T; Simon, R; Nilsson, KP; Thueringer, A; Kashofer, K; Haybaeck, J; Denk, H; Abuja, PM; Zatloukal, K Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.
Gastroenterology. 2011; 141(3):1080-1090.e1-1080-1090.e7 Doi: 10.1053/j.gastro.2011.05.039
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Muik, M; Fahrner, M; Schindl, R; Stathopulos, P; Frischauf, I; Derler, I; Plenk, P; Lackner, B; Groschner, K; Ikura, M; Romanin, C STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation.
EMBO J. 2011; 30(9): 1678-1689. Doi: 10.1038/emboj.2011.79 [OPEN ACCESS]
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Riederer, M; Lechleitner, M; Hrzenjak, A; Koefeler, H; Desoye, G; Heinemann, A; Frank, S Endothelial lipase (EL) and EL-generated lysophosphatidylcholines promote IL-8 expression in endothelial cells.
Atherosclerosis. 2011; 214(2):338-344 Doi: 10.1016/j.atherosclerosis.2010.11.007 [OPEN ACCESS]
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Tschische, P; Tadagaki, K; Kamal, M; Jockers, R; Waldhoer, M Heteromerization of human cytomegalovirus encoded chemokine receptors.
Biochem Pharmacol. 2011; 82(6):610-619 Doi: 10.1016/j.bcp.2011.06.009 [OPEN ACCESS]
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