Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: SIGNAL TRANSDUCTION - , . Treffer: 152

2020

Golob-Schwarzl, N; Puchas, P; Gogg-Kamerer, M; Weichert, W; Göppert, B; Haybaeck, J New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.
Anticancer Res. 2020; 40(6):3109-3118
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2019

Willecke, F; Rupprecht, B; Gissler, MC; Pfeiffer, K; Anto-Michel, N; Stachon, P; Wolf, D; Hilgendorf, I; Hoppe, N; Bode, C; Zirlik, A Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation.
J VASC RES. 2019; 56(6): 308-319.
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2018

Bourgeois, B; Madl, T Regulation of cellular senescence via the FOXO4-p53 axis.
FEBS Lett. 2018; 592(12):2083-2097 [OPEN ACCESS]
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Jahanafrooz, Z; Stallinger, A; Anders, I; Kleinegger, F; Lohberger, B; Durchschein, C; Bauer, R; Deutsch, A; Rinner, B; Kretschmer, N Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
Phytomedicine. 2018; 49(11):32-40
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Segerer, G; Engelmann, D; Kaestner, A; Trötzmüller, M; Köfeler, H; Stigloher, C; Thiele, C; Jeanclos, E; Gohla, A A phosphoglycolate phosphatase/AUM-dependent link between triacylglycerol turnover and epidermal growth factor signaling.
Biochim Biophys Acta. 2018; 1863(6):584-594
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Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 [OPEN ACCESS]
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2017

El Agha, E; Moiseenko, A; Kheirollahi, V; De Langhe, S; Crnkovic, S; Kwapiszewska, G; Szibor, M; Kosanovic, D; Schwind, F; Schermuly, RT; Henneke, I; MacKenzie, B; Quantius, J; Herold, S; Ntokou, A; Ahlbrecht, K; Braun, T; Morty, RE; Günther, A; Seeger, W; Bellusci, S Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.
Cell Stem Cell. 2017; 20(2):261-273 [OPEN ACCESS]
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Fasching, P; Stradner, M; Graninger, W; Dejaco, C; Fessler, J Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders.
Molecules. 2017; 22(1): [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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Grabner, GF; Zimmermann, R; Schicho, R; Taschler, U Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.
Pharmacol Ther. 2017; 175:35-46 [OPEN ACCESS]
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Mayr, C; Ocker, M; Ritter, M; Pichler, M; Neureiter, D; Kiesslich, T Biliary tract cancer stem cells - translational options and challenges.
World J Gastroenterol. 2017; 23(14):2470-2482 [OPEN ACCESS]
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 [OPEN ACCESS]
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Rashed, MH; Kanlikilicer, P; Rodriguez-Aguayo, C; Pichler, M; Bayraktar, R; Bayraktar, E; Ivan, C; Filant, J; Silva, A; Aslan, B; Denizli, M; Mitra, R; Ozpolat, B; Calin, GA; Sood, AK; Abd-Ellah, MF; Helal, GK; Berestein, GL Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget. 2017; 8(12):20145-20164 [OPEN ACCESS]
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Riedl, A; Schlederer, M; Pudelko, K; Stadler, M; Walter, S; Unterleuthner, D; Unger, C; Kramer, N; Hengstschläger, M; Kenner, L; Pfeiffer, D; Krupitza, G; Dolznig, H Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses.
J Cell Sci. 2017; 130(1):203-218 [OPEN ACCESS]
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Schanza, LM; Seles, M; Stotz, M; Fosselteder, J; Hutterer, GC; Pichler, M; Stiegelbauer, V MicroRNAs Associated with Von Hippel-Lindau Pathway in Renal Cell Carcinoma: A Comprehensive Review.
Int J Mol Sci. 2017; 18(11): [OPEN ACCESS]
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Windpassinger, C; Piard, J; Bonnard, C; Alfadhel, M; Lim, S; Bisteau, X; Blouin, S; Ali, NB; Ng, AYJ; Lu, H; Tohari, S; Talib, SZA; van Hul, N; Caldez, MJ; Van Maldergem, L; Yigit, G; Kayserili, H; Youssef, SA; Coppola, V; de Bruin, A; Tessarollo, L; Choi, H; Rupp, V; Roetzer, K; Roschger, P; Klaushofer, K; Altmüller, J; Roy, S; Venkatesh, B; Ganger, R; Grill, F; Ben Chehida, F; Wollnik, B; Altunoglu, U; Al Kaissi, A; Reversade, B; Kaldis, P CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
Am J Hum Genet. 2017; 101(3): 391-403. [OPEN ACCESS]
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2016

Barghash, A; Golob-Schwarzl, N; Helms, V; Haybaeck, J; Kessler, SM Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma.
Oncotarget. 2016; 7(31):49743-49750 [OPEN ACCESS]
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Birner, P; Heider, S; Petzelbauer, P; Wolf, P; Kornauth, C; Kuroll, M; Merkel, O; Steiner, G; Kishimoto, T; Rose-John, S; Soleiman, A; Moriggl, R; Kenner, L Interleukin-6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosus.
Exp Dermatol. 2016; 25(4):305-310 [OPEN ACCESS]
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Derler, I; Jardin, I; Stathopulos, PB; Muik, M; Fahrner, M; Zayats, V; Pandey, SK; Poteser, M; Lackner, B; Absolonova, M; Schindl, R; Groschner, K; Ettrich, R; Ikura, M; Romanin, C Cholesterol modulates Orai1 channel function.
Sci Signal. 2016; 9(412):ra10-ra10 [OPEN ACCESS]
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Hartmann, L; Dutta, S; Opatz, S; Vosberg, S; Reiter, K; Leubolt, G; Metzeler, KH; Herold, T; Bamopoulos, SA; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Hopfner, KP; Graf, A; Krebs, S; Blum, H; Middeke, JM; Stölzel, F; Thiede, C; Wolf, S; Bohlander, SK; Preiss, C; Chen-Wichmann, L; Wichmann, C; Sauerland, MC; Büchner, T; Berdel, WE; Wörmann, BJ; Braess, J; Hiddemann, W; Spiekermann, K; Greif, PA ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Nat Commun. 2016; 7:11733-11733 [OPEN ACCESS]
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Kienesberger, S; Cox, LM; Livanos, A; Zhang, XS; Chung, J; Perez-Perez, GI; Gorkiewicz, G; Zechner, EL; Blaser, MJ Gastric Helicobacter pylori Infection Affects Local and Distant Microbial Populations and Host Responses.
Cell Rep. 2016; 14(6):1395-1407 [OPEN ACCESS]
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Kirschmer, N; Bandleon, S; von Ehrlich-Treuenstätt, V; Hartmann, S; Schaaf, A; Lamprecht, AK; Miranda-Laferte, E; Langsenlehner, T; Ritter, O; Eder, P TRPC4α and TRPC4β Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation.
PLoS One. 2016; 11(12):e0168446-e0168446 [OPEN ACCESS]
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Modak, M; Majdic, O; Cejka, P; Jutz, S; Puck, A; Gerwien, JG; Steinberger, P; Zlabinger, GJ; Strobl, H; Stöckl, J Engagement of distinct epitopes on CD43 induces different co-stimulatory pathways in human T cells.
Immunology. 2016; 149(3):280-296 [OPEN ACCESS]
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Ohtsuka, M; Ling, H; Ivan, C; Pichler, M; Matsushita, D; Goblirsch, M; Stiegelbauer, V; Shigeyasu, K; Zhang, X; Chen, M; Vidhu, F; Bartholomeusz, GA; Toiyama, Y; Kusunoki, M; Doki, Y; Mori, M; Song, S; Gunther, JR; Krishnan, S; Slaby, O; Goel, A; Ajani, JA; Radovich, M; Calin, GA H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.
EBioMedicine. 2016; 13(3):113-124 [OPEN ACCESS]
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Pasterk, L; Lemesch, S; Leber, B; Trieb, M; Curcic, S; Stadlbauer, V; Schuligoi, R; Schicho, R; Heinemann, A; Marsche, G Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression.
Sci Rep. 2016; 6(3):22104-22104 [OPEN ACCESS]
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Rainer, PP; Kass, DA Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G.
Cardiovasc Res. 2016; 111(2):154-162 [OPEN ACCESS]
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Ritter, C; Fan, K; Paulson, KG; Nghiem, P; Schrama, D; Becker, JC Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma.
Sci Rep. 2016; 6:21678-21678 [OPEN ACCESS]
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Schauberger, E; Peinhaupt, M; Cazares, T; Lindsley, AW Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets.
Curr Allergy Asthma Rep. 2016; 16(7):48-48 [OPEN ACCESS]
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Scheipl, S; Barnard, M; Cottone, L; Jorgensen, M; Drewry, DH; Zuercher, WJ; Turlais, F; Ye, H; Leite, AP; Smith, JA; Leithner, A; Möller, P; Brüderlein, S; Guppy, N; Amary, F; Tirabosco, R; Strauss, SJ; Pillay, N; Flanagan, AM EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.
J Pathol. 2016; 239(3):320-334 [OPEN ACCESS]
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Stradner, MH; Cheung, KP; Lasorella, A; Goldrath, AW; D'Cruz, LM Id2 regulates hyporesponsive invariant natural killer T cells.
Immunol Cell Biol. 2016; 94(7):640-645 [OPEN ACCESS]
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Svobodova, B; Groschner, K Reprint of "Mechanisms of lipid regulation and lipid gating in TRPC channels".
Cell Calcium. 2016; 60(2):133-141
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Trivanović, D; Jauković, A; Krstić, J; Nikolić, S; Okić Djordjević, I; Kukolj, T; Obradović, H; Mojsilović, S; Ilić, V; Santibanez, JF; Bugarski, D Inflammatory cytokines prime adipose tissue mesenchymal stem cells to enhance malignancy of MCF-7 breast cancer cells via transforming growth factor-β1.
IUBMB Life. 2016; 68(3): 190-200. [OPEN ACCESS]
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Voelkl, J; Alesutan, I; Primessnig, U; Feger, M; Mia, S; Jungmann, A; Castor, T; Viereck, R; Stöckigt, F; Borst, O; Gawaz, M; Schrickel, JW; Metzler, B; Katus, HA; Müller, OJ; Pieske, B; Heinzel, FR; Lang, F AMP-activated protein kinase α1-sensitive activation of AP-1 in cardiomyocytes.
J Mol Cell Cardiol. 2016; 97(4):36-43
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2015

Berghold, VM; Gauster, M; Hemmings, DG; Moser, G; Kremshofer, J; Siwetz, M; Sundl, M; Huppertz, B Phospholipid scramblase 1 (PLSCR1) in villous trophoblast of the human placenta.
Histochem Cell Biol. 2015; 143(4):381-396
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Chen, Y; Guldiken, N; Spurny, M; Mohammed, HH; Haybaeck, J; Pollheimer, MJ; Fickert, P; Gassler, N; Jeon, MK; Trautwein, C; Strnad, P Loss of keratin 19 favours the development of cholestatic liver disease through decreased ductular reaction.
J Pathol. 2015; 237(3):343-354
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Crescenzo, R; Abate, F; Lasorsa, E; Tabbo', F; Gaudiano, M; Chiesa, N; Di Giacomo, F; Spaccarotella, E; Barbarossa, L; Ercole, E; Todaro, M; Boi, M; Acquaviva, A; Ficarra, E; Novero, D; Rinaldi, A; Tousseyn, T; Rosenwald, A; Kenner, L; Cerroni, L; Tzankov, A; Ponzoni, M; Paulli, M; Weisenburger, D; Chan, WC; Iqbal, J; Piris, MA; Zamo', A; Ciardullo, C; Rossi, D; Gaidano, G; Pileri, S; Tiacci, E; Falini, B; Shultz, LD; Mevellec, L; Vialard, JE; Piva, R; Bertoni, F; Rabadan, R; Inghirami, G; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium “Genetics-Driven Targeted Management of Lymphoid Malignancies” Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Cancer Cell. 2015; 27(4):516-532 [OPEN ACCESS]
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Fabro, AT; da Silva, PH; Zocolaro, WS; de Almeida, MS; Rangel, MP; de Oliveira, CC; Minatel, IO; Prando, ED; Rainho, CA; Teodoro, WR; Velosa, AP; Saber, AM; Parra-Cuentas, ER; Popper, HH; Capelozzi, VL The Th17 pathway in the peripheral lung microenvironment interacts with expression of collagen V in the late state of experimental pulmonary fibrosis.
Immunobiology. 2015; 220(1):124-135
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Farzi, A; Reichmann, F; Holzer, P The homeostatic role of neuropeptide Y in immune function and its impact on mood and behaviour.
Acta Physiol (Oxf). 2015; 213(3):603-627 [OPEN ACCESS]
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Izzo, AA; Muccioli, GG; Ruggieri, MR; Schicho, R Endocannabinoids and the Digestive Tract and Bladder in Health and Disease.
Handb Exp Pharmacol. 2015; 231(10):423-447
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Jimenez, K; Khare, V; Evstatiev, R; Kulnigg-Dabsch, S; Jambrich, M; Strobl, H; Gasche, C Increased expression of HIF2α during iron deficiency-associated megakaryocytic differentiation.
J Thromb Haemost. 2015; 13(6):1113-1127 [OPEN ACCESS]
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Krstić, J; Trivanović, D; Mojsilović, S; Santibanez, JF Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression.
Oxid Med Cell Longev. 2015; 2015(3): 654594-654594. [OPEN ACCESS]
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Laszlo, V; Hoda, MA; Garay, T; Pirker, C; Ghanim, B; Klikovits, T; Dong, YW; Rozsas, A; Kenessey, I; Szirtes, I; Grusch, M; Jakopovic, M; Samarzija, M; Brcic, L; Kern, I; Rozman, A; Popper, H; Zöchbauer-Müller, S; Heller, G; Altenberger, C; Ziegler, B; Klepetko, W; Berger, W; Dome, B; Hegedus, B Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
J Pathol. 2015; 237(2):203-214
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Ortega, M; Bhatnagar, H; Lin, AP; Wang, L; Aster, JC; Sill, H; Aguiar, RC A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies.
Leukemia. 2015; 29(4):968-976 [OPEN ACCESS]
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Pugliese, SC; Poth, JM; Fini, MA; Olschewski, A; El Kasmi, KC; Stenmark, KR The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.
Am J Physiol Lung Cell Mol Physiol. 2015; 308(3):L229-L252 [OPEN ACCESS]
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Ravindran Menon, D; Das, S; Krepler, C; Vultur, A; Rinner, B; Schauer, S; Kashofer, K; Wagner, K; Zhang, G; Bonyadi Rad, E; Haass, NK; Soyer, HP; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H A stress-induced early innate response causes multidrug tolerance in melanoma.
Oncogene. 2015; 34(34):4448-4459 [OPEN ACCESS]
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Reinisch, A; Chan, SM; Thomas, D; Majeti, R Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells.
Semin Hematol. 2015; 52(3): 150-164. [OPEN ACCESS]
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Tabeling, C; Yu, H; Wang, L; Ranke, H; Goldenberg, NM; Zabini, D; Noe, E; Krauszman, A; Gutbier, B; Yin, J; Schaefer, M; Arenz, C; Hocke, AC; Suttorp, N; Proia, RL; Witzenrath, M; Kuebler, WM CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.
Proc Natl Acad Sci U S A. 2015; 112(13):E1614-E1623 [OPEN ACCESS]
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Wende, AR; O'Neill, BT; Bugger, H; Riehle, C; Tuinei, J; Buchanan, J; Tsushima, K; Wang, L; Caro, P; Guo, A; Sloan, C; Kim, BJ; Wang, X; Pereira, RO; McCrory, MA; Nye, BG; Benavides, GA; Darley-Usmar, VM; Shioi, T; Weimer, BC; Abel, ED Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Mol Cell Biol. 2015; 35(5): 831-846. [OPEN ACCESS]
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Wiesner, T; Lee, W; Obenauf, AC; Ran, L; Murali, R; Zhang, QF; Wong, EW; Hu, W; Scott, SN; Shah, RH; Landa, I; Button, J; Lailler, N; Sboner, A; Gao, D; Murphy, DA; Cao, Z; Shukla, S; Hollmann, TJ; Wang, L; Borsu, L; Merghoub, T; Schwartz, GK; Postow, MA; Ariyan, CE; Fagin, JA; Zheng, D; Ladanyi, M; Busam, KJ; Berger, MF; Chen, Y; Chi, P Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature. 2015; 526(7573):453-457 [OPEN ACCESS]
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Zanini, S; Giovinazzo, F; Alaimo, D; Lawrence, B; Pfragner, R; Bassi, C; Modlin, I; Kidd, M GNA15 expression in small intestinal neuroendocrine neoplasia: functional and signalling pathway analyses.
Cell Signal. 2015; 27(5):899-907
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