Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: SARCOPLASMIC RETICULUM - METABOLISM , . Treffer: 45

2021

Jin, G; Manninger, M; Adelsmayr, G; Schwarzl, M; Alogna, A; Schönleitner, P; Zweiker, D; Blaschke, F; Sherif, M; Radulovic, S; Wakula, P; Schauer, S; Höfler, G; Reiter, U; Reiter, G; Post, H; Scherr, D; Acsai, K; Antoons, G; Pieske, B; Heinzel, FR Cellular contribution to left and right atrial dysfunction in chronic arterial hypertension in pigs.
ESC Heart Fail. 2021; 8(1):151-161 Doi: 10.1002/ehf2.13087 [OPEN ACCESS]
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2018

Fischer, TH; Eiringhaus, J; Dybkova, N; Saadatmand, A; Pabel, S; Weber, S; Wang, Y; Köhn, M; Tirilomis, T; Ljubojevic, S; Renner, A; Gummert, J; Maier, LS; Hasenfuß, G; El-Armouche, A; Sossalla, S Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure.
Eur J Heart Fail. 2018; 20(12):1673-1685 Doi: 10.1002/ejhf.1297 [OPEN ACCESS]
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2014

Navarro-Dorado, J; Garcia-Alonso, M; van Breemen, C; Tejerina, T; Fameli, N Calcium oscillations in human mesenteric vascular smooth muscle.
Biochem Biophys Res Commun. 2014; 445(1): 84-88. Doi: 10.1016/j.bbrc.2014.01.150 [OPEN ACCESS]
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Sedej, S; Schmidt, A; Denegri, M; Walther, S; Matovina, M; Arnstein, G; Gutschi, EM; Windhager, I; Ljubojević, S; Negri, S; Heinzel, FR; Bisping, E; Vos, MA; Napolitano, C; Priori, SG; Kockskämper, J; Pieske, B Subclinical abnormalities in sarcoplasmic reticulum Ca(2+) release promote eccentric myocardial remodeling and pump failure death in response to pressure overload.
J Am Coll Cardiol. 2014; 63(15):1569-1579 Doi: 10.1016/j.jacc.2013.11.010 [OPEN ACCESS]
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2013

Bito, V; Biesmans, L; Gellen, B; Antoons, G; Macquaide, N; Rouet-Benzineb, P; Pezet, M; Mercadier, JJ; Sipido, KR FKBP12.6 overexpression does not protect against remodelling after myocardial infarction.
Exp Physiol. 2013; 98(1):134-148 Doi: 10.1113/expphysiol.2011.064089 [OPEN ACCESS]
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Dries, E; Bito, V; Lenaerts, I; Antoons, G; Sipido, KR; Macquaide, N Selective modulation of coupled ryanodine receptors during microdomain activation of calcium/calmodulin-dependent kinase II in the dyadic cleft.
Circ Res. 2013; 113(11):1242-1252 Doi: 10.1161/CIRCRESAHA.113.301896 [OPEN ACCESS]
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Oberhofer, M; Tian, Q; Ruppenthal, S; Wegener, S; Reil, JC; Körbel, C; Hammer, K; Menger, M; Neuberger, HR; Kaestner, L; Lipp, P Calcium dysregulation in ventricular myocytes from mice expressing constitutively active Rac1.
Cell Calcium. 2013; 54(1):26-36 Doi: 10.1016/j.ceca.2013.03.006
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Sipido, KR; Acsai, K; Antoons, G; Bito, V; Macquaide, N T-tubule remodelling and ryanodine receptor organization modulate sodium-calcium exchange.
Adv Exp Med Biol. 2013; 961(3):375-383 Doi: 10.1007/978-1-4614-4756-6_32
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Sivakumaran, V; Stanley, BA; Tocchetti, CG; Ballin, JD; Caceres, V; Zhou, L; Keceli, G; Rainer, PP; Lee, DI; Huke, S; Ziolo, MT; Kranias, EG; Toscano, JP; Wilson, GM; O'Rourke, B; Kass, DA; Mahaney, JE; Paolocci, N HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Antioxid Redox Signal. 2013; 19(11):1185-1197 Doi: 10.1089/ars.2012.5057 [OPEN ACCESS]
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2012

Sacherer, M; Sedej, S; Wakuła, P; Wallner, M; Vos, MA; Kockskämper, J; Stiegler, P; Sereinigg, M; von Lewinski, D; Antoons, G; Pieske, BM; Heinzel, FR; CONTICA investigators JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.
Br J Pharmacol. 2012; 167(3):493-504 Doi: 10.1111/j.1476-5381.2012.01995.x [OPEN ACCESS]
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2011

Acsai, K; Antoons, G; Livshitz, L; Rudy, Y; Sipido, KR Microdomain [Ca²⁺] near ryanodine receptors as reported by L-type Ca²⁺ and Na+/Ca²⁺ exchange currents.
J Physiol. 2011; 589(Pt 10):2569-2583 Doi: 10.1113/jphysiol.2010.202663 [OPEN ACCESS]
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Biesmans, L; Macquaide, N; Heinzel, FR; Bito, V; Smith, GL; Sipido, KR Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density.
PLoS One. 2011; 6(10):e25100-e25100 Doi: 10.1371/journal.pone.0025100 [OPEN ACCESS]
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2010

Sedej, S; Heinzel, FR; Walther, S; Dybkova, N; Wakula, P; Groborz, J; Gronau, P; Maier, LS; Vos, MA; Lai, FA; Napolitano, C; Priori, SG; Kockskämper, J; Pieske, B Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation.
Cardiovasc Res. 2010; 87(1):50-59 Doi: 10.1093/cvr/cvq007 [OPEN ACCESS]
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2009

Goetzenich, A; Schroth, SC; Emmig, U; Autschbach, R; Pieske, B; Rossaint, R; Christiansen, S Hypothermia exerts negative inotropy in human atrial preparations: in vitro-comparison to rabbit myocardium.
J Cardiovasc Surg (Torino). 2009; 50(2):239-245
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Lenaerts, I; Bito, V; Heinzel, FR; Driesen, RB; Holemans, P; D'hooge, J; Heidbüchel, H; Sipido, KR; Willems, R Ultrastructural and functional remodeling of the coupling between Ca2+ influx and sarcoplasmic reticulum Ca2+ release in right atrial myocytes from experimental persistent atrial fibrillation.
Circ Res. 2009; 105(9): 876-885. Doi: 10.1161/CIRCRESAHA.109.206276 [OPEN ACCESS]
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2008

Heinzel, FR; Bito, V; Biesmans, L; Wu, M; Detre, E; von Wegner, F; Claus, P; Dymarkowski, S; Maes, F; Bogaert, J; Rademakers, F; D'hooge, J; Sipido, K Remodeling of T-tubules and reduced synchrony of Ca2+ release in myocytes from chronically ischemic myocardium.
Circ Res. 2008; 102(3): 338-346. Doi: 10.1161/CIRCRESAHA.107.160085 [OPEN ACCESS]
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2007

Antoons, G; Volders, PG; Stankovicova, T; Bito, V; Stengl, M; Vos, MA; Sipido, KR Window Ca2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block.
J Physiol. 2007; 579(Pt 1):147-160 Doi: 10.1113/jphysiol.2006.124222 [OPEN ACCESS]
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2006

Schillinger, W; Teucher, N; Christians, C; Kohlhaas, M; Sossalla, S; Van Nguyen, P; Schmidt, AG; Schunck, O; Nebendahl, K; Maier, LS; Zeitz, O; Hasenfuss, G High intracellular Na+ preserves myocardial function at low heart rates in isolated myocardium from failing hearts.
Eur J Heart Fail. 2006; 8(7): 673-680. Doi: 10.1016/j.ejheart.2006.01.013 [OPEN ACCESS]
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2005

Di Biase, V; Franzini-Armstrong, C Evolution of skeletal type e-c coupling: a novel means of controlling calcium delivery.
J Cell Biol. 2005; 171(4):695-704 Doi: 10.1083/jcb.200503077 [OPEN ACCESS]
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Knot, HJ; Laher, I; Sobie, EA; Guatimosim, S; Gomez-Viquez, L; Hartmann, H; Song, LS; Lederer, WJ; Graier, WF; Malli, R; Frieden, M; Petersen, OH Twenty years of calcium imaging: cell physiology to dye for.
MOL INTERV. 2005; 5(2): 112-127. Doi: 10.1124/mi.5.2.8 [OPEN ACCESS]
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Maier, LS; Wahl-Schott, C; Horn, W; Weichert, S; Pagel, C; Wagner, S; Dybkova, N; Müller, OJ; Näbauer, M; Franz, WM; Pieske, B Increased SR Ca2+ cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats.
Cardiovasc Res. 2005; 67(4):636-646 Doi: 10.1016/j.cardiores.2005.05.006 [OPEN ACCESS]
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von Lewinski, D; Bruns, S; Walther, S; Kögler, H; Pieske, B Insulin causes Ca2+i-dependent and Ca2+i-independent positive inotropic effects in failing human myocardium.
Circulation. 2005; 111(20):2588-2595 Doi: 10.1161/CIRCULATIONAHA.104.497461 [OPEN ACCESS]
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2004

Hong, Z; Olschewski, A; Reeve, HL; Nelson, DP; Hong, F; Weir, EK Nordexfenfluramine causes more severe pulmonary vasoconstriction than dexfenfluramine.
AMER J PHYSIOL-LUNG CELL M PH 2004 286: L531-L538. Doi: 10.1152/ajplung.00247.2003 [OPEN ACCESS]
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Liu, X; Groschner, K; Ambudkar, IS Distinct Ca(2+)-permeable cation currents are activated by internal Ca(2+)-store depletion in RBL-2H3 cells and human salivary gland cells, HSG and HSY.
J Membr Biol. 2004; 200(2):93-104 Doi: 10.1007/s00232-004-0698-3
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2003

Antoons, G; Ver Heyen, M; Raeymaekers, L; Vangheluwe, P; Wuytack, F; Sipido, KR Ca2+ uptake by the sarcoplasmic reticulum in ventricular myocytes of the SERCA2b/b mouse is impaired at higher Ca2+ loads only.
Circ Res. 2003; 92(8):881-887 Doi: 10.1161/01.RES.0000069032.81501.98 [OPEN ACCESS]
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Brittsan, AG; Ginsburg, KS; Chu, G; Yatani, A; Wolska, BM; Schmidt, AG; Asahi, M; MacLennan, DH; Bers, DM; Kranias, EG Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport.
Circ Res. 2003; 92(7): 769-776. Doi: 10.1161/01.RES.0000066661.49920.59 [OPEN ACCESS]
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von Lewinski, D; Stumme, B; Maier, LS; Luers, C; Bers, DM; Pieske, B Stretch-dependent slow force response in isolated rabbit myocardium is Na+ dependent.
Cardiovasc Res. 2003; 57(4):1052-1061 Doi: 10.1016/S0008-6363(02)00830-1 [OPEN ACCESS]
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von Lewinski, D; Voss, K; Hülsmann, S; Kögler, H; Pieske, B Insulin-like growth factor-1 exerts Ca2+-dependent positive inotropic effects in failing human myocardium.
Circ Res. 2003; 92(2):169-176 Doi: 10.1161/01.RES.0000051885.70159.12 [OPEN ACCESS]
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Zhao, W; Frank, KF; Chu, G; Gerst, MJ; Schmidt, AG; Ji, Y; Periasamy, M; Kranias, EG Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state.
Cardiovasc Res. 2003; 57(1): 71-81. Doi: 10.1016/S0008-6363(02)00609-0 [OPEN ACCESS]
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2002

Antoons, G; Mubagwa, K; Nevelsteen, I; Sipido, KR Mechanisms underlying the frequency dependence of contraction and [Ca(2+)](i) transients in mouse ventricular myocytes.
J Physiol. 2002; 543(Pt 3):889-898 Doi: 10.1113/jphysiol.2002.025619 [OPEN ACCESS]
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Hasenfuss, G; Pieske, B Calcium cycling in congestive heart failure.
J Mol Cell Cardiol. 2002; 34(8):951-969 Doi: 10.1006/jmcc.2002.2037
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Heinzel, FR; Bito, V; Volders, PG; Antoons, G; Mubagwa, K; Sipido, KR Spatial and temporal inhomogeneities during Ca2+ release from the sarcoplasmic reticulum in pig ventricular myocytes.
Circ Res. 2002; 91(11):1023-1030 Doi: 10.1161/01.RES.0000045940.67060.DD [OPEN ACCESS]
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Kiriazis, H; Sato, Y; Kadambi, VJ; Schmidt, AG; Gerst, MJ; Hoit, BD; Kranias, EG Hypertrophy and functional alterations in hyperdynamic phospholamban-knockout mouse hearts under chronic aortic stenosis.
Cardiovasc Res. 2002; 53(2): 372-381. Doi: 10.1016/S0008-6363(01)00487-4 [OPEN ACCESS]
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Kockskämper, J; Blatter, LA Subcellular Ca2+ alternans represents a novel mechanism for the generation of arrhythmogenic Ca2+ waves in cat atrial myocytes.
J Physiol. 2002; 545(Pt 1):65-79 Doi: 10.1113/jphysiol.2002.025502 [OPEN ACCESS]
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Pieske, B; Kockskämper, J Alternans goes subcellular: a disease of the ryanodine receptor?
Circ Res. 2002; 91(7):553-555 Doi: 10.1161/01.RES.0000036862.37203.F4 [OPEN ACCESS]
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Pieske, B; Maier, LS; Schmidt-Schweda, S Sarcoplasmic reticulum Ca2+ load in human heart failure.
Basic Res Cardiol. 2002; 97 Suppl 1: I63-I71. Doi: 10.1007/s003950200032
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Schmidt, AG; Zhai, J; Carr, AN; Gerst, MJ; Lorenz, JN; Pollesello, P; Annila, A; Hoit, BD; Kranias, EG Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure.
Cardiovasc Res. 2002; 56(2): 248-259. Doi: 10.1016/S0008-6363(02)00541-2 [OPEN ACCESS]
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2001

Most, P; Bernotat, J; Ehlermann, P; Pleger, ST; Reppel, M; Börries, M; Niroomand, F; Pieske, B; Janssen, PM; Eschenhagen, T; Karczewski, P; Smith, GL; Koch, WJ; Katus, HA; Remppis, A S100A1: a regulator of myocardial contractility.
Proc Natl Acad Sci U S A. 2001; 98(24):13889-13894 Doi: 10.1073/pnas.241393598 [OPEN ACCESS]
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Ver Heyen, M; Heymans, S; Antoons, G; Reed, T; Periasamy, M; Awede, B; Lebacq, J; Vangheluwe, P; Dewerchin, M; Collen, D; Sipido, K; Carmeliet, P; Wuytack, F Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart.
Circ Res. 2001; 89(9):838-846 Doi: 10.1161/hh2101.098466 [OPEN ACCESS]
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2000

Maier, LS; Barckhausen, P; Weisser, J; Aleksic, I; Baryalei, M; Pieske, B Ca(2+) handling in isolated human atrial myocardium.
Am J Physiol Heart Circ Physiol. 2000; 279(3):H952-H958 Doi: 10.1152/ajpheart.2000.279.3.H952 [OPEN ACCESS]
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Maier, LS; Bers, DM; Pieske, B Differences in Ca(2+)-handling and sarcoplasmic reticulum Ca(2+)-content in isolated rat and rabbit myocardium.
J Mol Cell Cardiol. 2000; 32(12):2249-2258 Doi: 10.1006/jmcc.2000.1252
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Zhai, J; Schmidt, AG; Hoit, BD; Kimura, Y; MacLennan, DH; Kranias, EG Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo.
J Biol Chem. 2000; 275(14): 10538-10544. Doi: 10.1074/jbc.275.14.10538 [OPEN ACCESS]
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1999

Pieske, B; Maier, LS; Bers, DM; Hasenfuss, G Ca2+ handling and sarcoplasmic reticulum Ca2+ content in isolated failing and nonfailing human myocardium.
Circ Res. 1999; 85(1):38-46 Doi: 10.1161/01.RES.85.1.38 [OPEN ACCESS]
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1996

Pieske, B; Sütterlin, M; Schmidt-Schweda, S; Minami, K; Meyer, M; Olschewski, M; Holubarsch, C; Just, H; Hasenfuss, G Diminished post-rest potentiation of contractile force in human dilated cardiomyopathy. Functional evidence for alterations in intracellular Ca2+ handling.
J Clin Invest. 1996; 98(3):764-776 Doi: 10.1172/JCI118849 [OPEN ACCESS]
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1990

Butkow, N; Wheatley, AM; Lippe, IT; Marcus, RH; Rosendorff, C The role of calcium in the enhanced myocardial contractility of the hyperthyroid rat heart.
Basic Res Cardiol. 1990; 85(3):297-306 Doi: 10.1007/BF01907118
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