Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: STAT3, . Treffer: 41

2020

Pichler, M; Rodriguez-Aguayo, C; Nam, SY; Dragomir, MP; Bayraktar, R; Anfossi, S; Knutsen, E; Ivan, C; Fuentes-Mattei, E; Lee, SK; Ling, H; Catela Ivkovic, T; Huang, G; Huang, L; Okugawa, Y; Katayama, H; Taguchi, A; Bayraktar, E; Bhattacharya, R; Amero, P; He, WR; Tran, AM; Vychytilova-Faltejskova, P; Klec, C; Bonilla, DL; Zhang, X; Kapitanovic, S; Loncar, B; Gafà, R; Wang, Z; Cristini, V; Hanash, SM; Bar-Eli, M; Lanza, G; Slaby, O; Goel, A; Rigoutsos, I; Lopez-Berestein, G; Calin, GA Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer.
Gut. 2020; [OPEN ACCESS]
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2019

Aigner, P; Mizutani, T; Horvath, J; Eder, T; Heber, S; Lind, K; Just, V; Moll, HP; Yeroslaviz, A; Fischer, MJM; Kenner, L; Győrffy, B; Sill, H; Grebien, F; Moriggl, R; Casanova, E; Stoiber, D STAT3β is a tumor suppressor in acute myeloid leukemia.
Blood Adv. 2019; 3(13): 1989-2002. [OPEN ACCESS]
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Kleinegger, F; Hofer, E; Wodlej, C; Golob-Schwarzl, N; Birkl-Toeglhofer, AM; Stallinger, A; Petzold, J; Orlova, A; Krassnig, S; Reihs, R; Niedrist, T; Mangge, H; Park, YN; Thalhammer, M; Aigelsreiter, A; Lax, S; Garbers, C; Fickert, P; Rose-John, S; Moriggl, R; Rinner, B; Haybaeck, J Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(2):308-321 [OPEN ACCESS]
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Lohberger, B; Kaltenegger, H; Weigl, L; Mann, A; Kullich, W; Stuendl, N; Leithner, A; Steinecker-Frohnwieser, B Mechanical exposure and diacerein treatment modulates integrin-FAK-MAPKs mechanotransduction in human osteoarthritis chondrocytes.
Cell Signal. 2019; 56(2):23-30 [OPEN ACCESS]
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Lokau, J; Schoeder, V; Haybaeck, J; Garbers, C Jak-Stat Signaling Induced by Interleukin-6 Family Cytokines in Hepatocellular Carcinoma.
Cancers (Basel). 2019; 11(11): [OPEN ACCESS]
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Plastira, I; Joshi, L; Bernhart, E; Schoene, J; Specker, E; Nazare, M; Sattler, W Small-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells.
Front Cell Neurosci. 2019; 13: 531-531. [OPEN ACCESS]
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Prutsch, N; Gurnhofer, E; Suske, T; Liang, HC; Schlederer, M; Roos, S; Wu, LC; Simonitsch-Klupp, I; Alvarez-Hernandez, A; Kornauth, C; Leone, DA; Svinka, J; Eferl, R; Limberger, T; Aufinger, A; Shirsath, N; Wolf, P; Hielscher, T; Aberger, F; Schmoellerl, J; Stoiber, D; Strobl, B; Jäger, U; Staber, PB; Grebien, F; Moriggl, R; Müller, M; Inghirami, GG; Sanda, T; Look, AT; Turner, SD; Kenner, L; Merkel, O Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.
Leukemia. 2019; 33(3):696-709
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2018

Hasenoehrl, C; Feuersinger, D; Sturm, EM; Bärnthaler, T; Heitzer, E; Graf, R; Grill, M; Pichler, M; Beck, S; Butcher, L; Thomas, D; Ferreirós, N; Schuligoi, R; Schweiger, C; Haybaeck, J; Schicho, R G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.
Int J Cancer. 2018; 142(1):121-132 [OPEN ACCESS]
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Jahanafrooz, Z; Stallinger, A; Anders, I; Kleinegger, F; Lohberger, B; Durchschein, C; Bauer, R; Deutsch, A; Rinner, B; Kretschmer, N Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
Phytomedicine. 2018; 49(11):32-40
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Zhou, XA; Louissaint, A; Wenzel, A; Yang, J; Martinez-Escala, ME; Moy, AP; Morgan, EA; Paxton, CN; Hong, B; Andersen, EF; Guitart, J; Behdad, A; Cerroni, L; Weinstock, DM; Choi, J Genomic Analyses Identify Recurrent Alterations in Immune Evasion Genes in Diffuse Large B-Cell Lymphoma, Leg Type.
J INVEST DERMATOL. 2018; 138(11): 2365-2376. [OPEN ACCESS]
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2017

Arzt, L; Halbwedl, I; Gogg-Kamerer, M; Popper, HH Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma.
Pathol Oncol Res. 2017; 23(3):595-605 [OPEN ACCESS]
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González-Vela, MDC; Curiel-Olmo, S; Derdak, S; Beltran, S; Santibañez, M; Martínez, N; Castillo-Trujillo, A; Gut, M; Sánchez-Pacheco, R; Almaraz, C; Cereceda, L; Llombart, B; Agraz-Doblas, A; Revert-Arce, J; López Guerrero, JA; Mollejo, M; Marrón, PI; Ortiz-Romero, P; Fernandez-Cuesta, L; Varela, I; Gut, I; Cerroni, L; Piris, MÁ; Vaqué, JP Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas.
J Invest Dermatol. 2017; 137(1):197-206 [OPEN ACCESS]
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Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 [OPEN ACCESS]
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Taniguchi, K; Moroishi, T; de Jong, PR; Krawczyk, M; Grebbin, BM; Luo, H; Xu, RH; Golob-Schwarzl, N; Schweiger, C; Wang, K; Di Caro, G; Feng, Y; Fearon, ER; Raz, E; Kenner, L; Farin, HF; Guan, KL; Haybaeck, J; Datz, C; Zhang, K; Karin, M YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Proc Natl Acad Sci U S A. 2017; 114(7):1643-1648 [OPEN ACCESS]
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Thangaratnarajah, C; Dinger, K; Vohlen, C; Klaudt, C; Nawabi, J; Lopez Garcia, E; Kwapiszewska, G; Dobner, J; Nüsken, KD; van Koningsbruggen-Rietschel, S; von Hörsten, S; Dötsch, J; Alejandre Alcázar, MA Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.
Am J Physiol Lung Cell Mol Physiol. 2017; 313(3):L491-L506 [OPEN ACCESS]
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2016

Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781 [OPEN ACCESS]
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Themanns, M; Mueller, KM; Kessler, SM; Golob-Schwarzl, N; Mohr, T; Kaltenecker, D; Bourgeais, J; Paier-Pourani, J; Friedbichler, K; Schneller, D; Schlederer, M; Zebedin-Brandl, E; Terracciano, LM; Han, X; Kenner, L; Wagner, KU; Mikulits, W; Kozlov, AV; Heim, MH; Gouilleux, F; Haybaeck, J; Moriggl, R Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
Sci Rep. 2016; 6(4):34719-34719 [OPEN ACCESS]
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Vieyra-Garcia, PA; Wei, T; Naym, DG; Fredholm, S; Fink-Puches, R; Cerroni, L; Odum, N; O'Malley, JT; Gniadecki, R; Wolf, P STAT3/5-Dependent IL9 Overexpression Contributes to Neoplastic Cell Survival in Mycosis Fungoides.
Clin Cancer Res. 2016; 22(13):3328-3339 [OPEN ACCESS]
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2015

Crescenzo, R; Abate, F; Lasorsa, E; Tabbo', F; Gaudiano, M; Chiesa, N; Di Giacomo, F; Spaccarotella, E; Barbarossa, L; Ercole, E; Todaro, M; Boi, M; Acquaviva, A; Ficarra, E; Novero, D; Rinaldi, A; Tousseyn, T; Rosenwald, A; Kenner, L; Cerroni, L; Tzankov, A; Ponzoni, M; Paulli, M; Weisenburger, D; Chan, WC; Iqbal, J; Piris, MA; Zamo', A; Ciardullo, C; Rossi, D; Gaidano, G; Pileri, S; Tiacci, E; Falini, B; Shultz, LD; Mevellec, L; Vialard, JE; Piva, R; Bertoni, F; Rabadan, R; Inghirami, G; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium “Genetics-Driven Targeted Management of Lymphoid Malignancies” Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Cancer Cell. 2015; 27(4):516-532 [OPEN ACCESS]
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Grabner, B; Schramek, D; Mueller, KM; Moll, HP; Svinka, J; Hoffmann, T; Bauer, E; Blaas, L; Hruschka, N; Zboray, K; Stiedl, P; Nivarthi, H; Bogner, E; Gruber, W; Mohr, T; Zwick, RH; Kenner, L; Poli, V; Aberger, F; Stoiber, D; Egger, G; Esterbauer, H; Zuber, J; Moriggl, R; Eferl, R; Győrffy, B; Penninger, JM; Popper, H; Casanova, E Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Nat Commun. 2015; 6(4):6285-6285 [OPEN ACCESS]
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Schiefer, AI; Vesely, P; Hassler, MR; Egger, G; Kenner, L The role of AP-1 and epigenetics in ALCL.
Front Biosci (Schol Ed). 2015; 7(5):226-235
PubMed

 

2014

Arzt, L; Kothmaier, H; Halbwedl, I; Quehenberger, F; Popper, HH Signal transducer and activator of transcription 1 (STAT1) acts like an oncogene in malignant pleural mesothelioma.
Virchows Arch. 2014; 465(1):79-88
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2013

Kargl, J; Haybaeck, J; Stančić, A; Andersen, L; Marsche, G; Heinemann, A; Schicho, R O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms.
J Mol Med (Berl). 2013; 91(4):449-458 [OPEN ACCESS]
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2012

Tsoi, LC; Spain, SL; Knight, J; Ellinghaus, E; Stuart, PE; Capon, F; Ding, J; Li, Y; Tejasvi, T; Gudjonsson, JE; Kang, HM; Allen, MH; McManus, R; Novelli, G; Samuelsson, L; Schalkwijk, J; Ståhle, M; Burden, AD; Smith, CH; Cork, MJ; Estivill, X; Bowcock, AM; Krueger, GG; Weger, W; Worthington, J; Tazi-Ahnini, R; Nestle, FO; Hayday, A; Hoffmann, P; Winkelmann, J; Wijmenga, C; Langford, C; Edkins, S; Andrews, R; Blackburn, H; Strange, A; Band, G; Pearson, RD; Vukcevic, D; Spencer, CC; Deloukas, P; Mrowietz, U; Schreiber, S; Weidinger, S; Koks, S; Kingo, K; Esko, T; Metspalu, A; Lim, HW; Voorhees, JJ; Weichenthal, M; Wichmann, HE; Chandran, V; Rosen, CF; Rahman, P; Gladman, DD; Griffiths, CE; Reis, A; Kere, J; Collaborative Association Study of Psoriasis (CASP); Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2; Nair, RP; Franke, A; Barker, JN; Abecasis, GR; Elder, JT; Trembath, RC Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
Nat Genet. 2012; 44(12):1341-1348 [OPEN ACCESS]
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2011

Beitzke, M; Enzinger, C; Windpassinger, C; Pfeifer, D; Fazekas, F; Woellner, C; Grimbacher, B; Kroisel, PM Community acquired Staphylococcus aureus meningitis and cerebral abscesses in a patient with a Hyper-IgE and a Dubowitz-like syndrome.
J Neurol Sci. 2011; 309(1-2):12-15 (- Case Report)
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Donnerer, J; Liebmann, I A fluorescence-immunohistochemical study on phosphorylation of ERK1/2, p38, and STAT3 in rat dorsal root ganglia following noxious stimulation of hind paw sensory neurons.
Tissue Cell. 2011; 43(3): 178-189.
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März-Weiss, P; Kunz, D; Bimmler, D; Berkemeier, C; Özbek, S; Dimitriades-Schmutz, B; Haybaeck, J; Otten, U; Graf, R Expression of pancreatitis-associated protein after traumatic brain injury: a mechanism potentially contributing to neuroprotection in human brain.
Cell Mol Neurobiol. 2011; 31(8):1141-1149
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2010

Fitzgerald, JS; Germeyer, A; Huppertz, B; Jeschke, U; Knofler, M; Moser, G; Scholz, C; Sonderegger, S; Toth, B; Markert, UR Governing the invasive trophoblast: current aspects on intra- and extracellular regulation.
AMER J REPROD IMMUNOL. 2010; 63(6): 492-505. [OPEN ACCESS]
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Hecker, M; Zaslona, Z; Kwapiszewska, G; Niess, G; Zakrzewicz, A; Hergenreider, E; Wilhelm, J; Marsh, LM; Sedding, D; Klepetko, W; Lohmeyer, J; Dimmeler, S; Seeger, W; Weissmann, N; Schermuly, RT; Kneidinger, N; Eickelberg, O; Morty, RE Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.
Am J Respir Crit Care Med. 2010; 182(6): 805-818. [OPEN ACCESS]
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Mair, M; Zollner, G; Schneller, D; Musteanu, M; Fickert, P; Gumhold, J; Schuster, C; Fuchsbichler, A; Bilban, M; Tauber, S; Esterbauer, H; Kenner, L; Poli, V; Blaas, L; Kornfeld, JW; Casanova, E; Mikulits, W; Trauner, M; Eferl, R Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Gastroenterology. 2010; 138(7):2499-2508
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Oberbach, A; Schlichting, N; Bluher, M; Kovacs, P; Till, H; Stolzenburg, JU; Neuhaus, J; Palmitate Induced IL-6 and MCP-1 Expression in Human Bladder Smooth Muscle Cells Provides a Link between Diabetes and Urinary Tract Infections.
PLoS One. 2010; 5(5):e10882-e10882 [OPEN ACCESS]
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Singh, TP; Schön, MP; Wallbrecht, K; Michaelis, K; Rinner, B; Mayer, G; Schmidbauer, U; Strohmaier, H; Wang, XJ; Wolf, P 8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involving CTLA4 signaling in a psoriasis-like skin disorder.
J Immunol. 2010; 184(12): 7257-7267. [OPEN ACCESS]
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2009

Meenhuis, A; Irandoust, M; Wölfler, A; Roovers, O; Valkhof, M; Touw, IP Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors.
Biochem J. 2009; 417(3):737-746 [OPEN ACCESS]
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Pflegerl, P; Vesely, P; Hantusch, B; Schlederer, M; Zenz, R; Janig, E; Steiner, G; Meixner, A; Petzelbauer, P; Wolf, P; Soleiman, A; Egger, G; Moriggl, R; Kishimoto, T; Wagner, EF; Kenner, L Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.
Proc Natl Acad Sci U S A. 2009; 106(48):20423-20428 [OPEN ACCESS]
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2008

Zollinger, A; Stuhmer, T; Chatterjee, M; Gattenlohner, S; Haralambieva, E; Muller-Hermelink, HK; Andrulis, M; Greiner, A; Wesemeier, C; Rath, JC; Einsele, H; Bargou, RC Combined functional and molecular analysis of tumor cell signaling defines 2 distinct myeloma subgroups: Akt-dependent and Akt-independent multiple myeloma.
Blood. 2008; 112(8):3403-3411 [OPEN ACCESS]
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2007

Mayer, C; Gruber, HJ; Landl, EM; Pailer, S; Scharnagl, H; Truschnig-Wilders, M; März, W Rosuvastatin reduces interleukin-6-induced expression of C-reactive protein in human hepatocytes in a STAT3- and C/EBP-dependent fashion.
INT J CLIN PHARM THERAPEUTICS. 2007; 45(6): 319-327.
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Sen, U; Herrmann, M; Herrmann, W; Tyagi, SC Synergism between AT1 receptor and hyperhomocysteinemia during vascular remodeling.
Clin Chem Lab Med. 2007; 45(12):1771-1776
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2006

Donnerer, J; Liebmann, I The NK1 receptor antagonist SR140333 inhibits capsaicin-induced ERK phosphorylation in sensory neurons.
Pharmacology. 2006; 77(3):144-149
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Krejsgaard, T; Vetter-Kauczok, CS; Woetmann, A; Lovato, P; Labuda, T; Eriksen, KW; Zhang, Q; Becker, JC; Odum, N Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma.
Leukemia. 2006; 20(10):1759-1766 [OPEN ACCESS]
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2005

Corvinus, FM; Orth, C; Moriggl, R; Tsareva, SA; Wagner, S; Pfitzner, EB; Baus, D; Kaufmann, R; Huber, LA; Zatloukal, K; Beug, H; Ohlschager, P; Schutz, A; Halbhuber, KJ; Friedrich, K Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth.
NEOPLASIA. 2005; 7(6): 545-555. [OPEN ACCESS]
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Donnerer, J; Liebmann, I; Schicho, R ERK and STAT3 phosphorylation in sensory neurons during capsaicin-induced impairment and nerve growth factor treatment.
PHARMACOLOGY. 2005; 75(3): 116-121.
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