Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: RECOMBINANT PROTEINS - GENETICS , . Treffer: 38

2017

Emmanouilidis, L; Schütz, U; Tripsianes, K; Madl, T; Radke, J; Rucktäschel, R; Wilmanns, M; Schliebs, W; Erdmann, R; Sattler, M Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19.
Nat Commun. 2017; 8(7):14635-14635 [OPEN ACCESS]
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2016

Biundo, A; Hromic, A; Pavkov-Keller, T; Gruber, K; Quartinello, F; Haernvall, K; Perz, V; Arrell, MS; Zinn, M; Ribitsch, D; Guebitz, GM Characterization of a poly(butylene adipate-co-terephthalate)- hydrolyzing lipase from Pelosinus fermentans.
Appl Microbiol Biotechnol. 2016; 100(4): 1753-1764. [OPEN ACCESS]
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Janowski, R; Scanu, S; Niessing, D; Madl, T Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Acta Crystallogr F Struct Biol Commun. 2016; 72(Pt 10):743-749 [OPEN ACCESS]
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Krainer, FW; Gerstmann, MA; Darnhofer, B; Birner-Gruenberger, R; Glieder, A Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris.
J Biotechnol. 2016; 233(31):181-189 [OPEN ACCESS]
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Voith von Voithenberg, L; Sánchez-Rico, C; Kang, HS; Madl, T; Zanier, K; Barth, A; Warner, LR; Sattler, M; Lamb, DC Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proc Natl Acad Sci U S A. 2016; 113(46):E7169-E7175 [OPEN ACCESS]
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Weinhandl, K; Ballach, M; Winkler, M; Ahmad, M; Glieder, A; Birner-Gruenberger, R; Fotheringham, I; Escalettes, F; Camattari, A Pichia pastoris mutants as host strains for efficient secretion of recombinant branched chain aminotransferase (BCAT).
J Biotechnol. 2016; 235(1):84-91
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2015

Haslbeck, V; Eckl, JM; Drazic, A; Rutz, DA; Lorenz, OR; Zimmermann, K; Kriehuber, T; Lindemann, C; Madl, T; Richter, K The activity of protein phosphatase 5 towards native clients is modulated by the middle- and C-terminal domains of Hsp90.
Sci Rep. 2015; 5(4):17058-17058 [OPEN ACCESS]
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Perz, V; Zumstein, MT; Sander, M; Zitzenbacher, S; Ribitsch, D; Guebitz, GM Biomimetic Approach to Enhance Enzymatic Hydrolysis of the Synthetic Polyester Poly(1,4-butylene adipate): Fusing Binding Modules to Esterases.
Biomacromolecules. 2015; 16(12): 3889-3896.
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2014

Lorenz, OR; Freiburger, L; Rutz, DA; Krause, M; Zierer, BK; Alvira, S; Cuéllar, J; Valpuesta, JM; Madl, T; Sattler, M; Buchner, J Modulation of the Hsp90 chaperone cycle by a stringent client protein.
Mol Cell. 2014; 53(6): 941-953. [OPEN ACCESS]
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2012

Rengachari, S; Bezerra, GA; Riegler-Berket, L; Gruber, CC; Sturm, C; Taschler, U; Boeszoermenyi, A; Dreveny, I; Zimmermann, R; Gruber, K; Oberer, M The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes.
Biochim Biophys Acta. 2012; 1821(7):1012-1021 [OPEN ACCESS]
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2011

Pival, SL; Birner-Gruenberger, R; Krump, C; Nidetzky, B D-Xylulose kinase from Saccharomyces cerevisiae: isolation and characterization of the highly unstable enzyme, recombinantly produced in Escherichia coli.
Protein Expr Purif. 2011; 79(2):223-230 [OPEN ACCESS]
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2010

Gruber, A; Cornaciu, I; Lass, A; Schweiger, M; Poeschl, M; Eder, C; Kumari, M; Schoiswohl, G; Wolinski, H; Kohlwein, SD; Zechner, R; Zimmermann, R; Oberer, M The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
J Biol Chem. 2010; 285(16): 12289-12298. [OPEN ACCESS]
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Mittermann, I; Zidarn, M; Silar, M; Markovic-Housley, Z; Aberer, W; Korosec, P; Kosnik, M; Valenta, R Recombinant allergen-based IgE testing to distinguish bee and wasp allergy.
J ALLERG CLIN IMMUNOL. 2010; 125(6): 1300-1307.
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2008

Hochrainer, K; Kroismayr, R; Baranyi, U; Binder, BR; Lipp, J Highly homologous HERC proteins localize to endosomes and exhibit specific interactions with hPLIC and Nm23B.
Cell Mol Life Sci. 2008; 65(13):2105-2117
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Schneider, A; Spitkovsky, D; Riess, P; Molcanyi, M; Kamisetti, N; Maegele, M; Hescheler, J; Schaefer, U "The good into the pot, the bad into the crop!"--a new technology to free stem cells from feeder cells.
PLoS ONE. 2008; 3(11): e3788-e3788. [OPEN ACCESS]
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2006

Adida, A; Spener, F Adipocyte-type fatty acid-binding protein as inter-compartmental shuttle for peroxisome proliferator activated receptor gamma agonists in cultured cell.
Biochim Biophys Acta. 2006; 1761(2):172-181 [OPEN ACCESS]
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Suck, R; Kamionka, T; Schäffer, B; Wahl, R; Nandy, A; Weber, B; Petersen, A; Birner-Grünberger, R; D V, SC; Keller, W; Fiebig, H; Cromwell, O Bacterially expressed and optimized recombinant Phl p 1 is immunobiochemically equivalent to natural Phl p 1.
Biochim Biophys Acta. 2006; 1764(11): 1701-1709. [OPEN ACCESS]
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2005

Ball, T; Edstrom, W; Mauch, L; Schmitt, J; Leistler, B; Fiebig, H; Sperr, WR; Hauswirth, AW; Valent, P; Kraft, D; Almo, SC; Valenta, R Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1.
FEBS J. 2005; 272(1): 217-227. [OPEN ACCESS]
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2004

Evgrafov, OV; Mersiyanova, I; Irobi, J; Van Den Bosch, L; Dierick, I; Leung, CL; Schagina, O; Verpoorten, N; Van Impe, K; Fedotov, V; Dadali, E; Auer-Grumbach, M; Windpassinger, C; Wagner, K; Mitrovic, Z; Hilton-Jones, D; Talbot, K; Martin, JJ; Vasserman, N; Tverskaya, S; Polyakov, A; Liem, RK; Gettemans, J; Robberecht, W; De Jonghe, P; Timmerman, V Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Nat Genet. 2004; 36(6):602-606 [OPEN ACCESS]
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McMullen, JR; Shioi, T; Huang, WY; Zhang, L; Tarnavski, O; Bisping, E; Schinke, M; Kong, S; Sherwood, MC; Brown, J; Riggi, L; Kang, PM; Izumo, S The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway.
J Biol Chem. 2004; 279(6):4782-4793 [OPEN ACCESS]
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2002

Vogel, A; Börchers, T; Marcus, K; Meyer, HE; Krebs, B; Spener, F Heterologous expression and characterization of recombinant purple acid phosphatase from red kidney bean.
Arch Biochem Biophys. 2002; 401(2):164-172
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2001

Hoffmann, M; Scharnagl, H; Panagiotou, E; Banghard, W; Wieland, H; März, W Diminished LDL receptor and high heparin binding of apolipoprotein E2 Sendai associated with lipoprotein glomerulopathy.
J AMER SOC NEPHROL 2001 12: 524-530. [OPEN ACCESS]
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Klade, CS; Voss, T; Krystek, E; Ahorn, H; Zatloukal, K; Pummer, K; Adolf, GR Identification of tumor antigens in renal cell carcinoma by serological proteome analysis.
Proteomics. 2001; 1(7):890-898
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2000

Abbadi, A; Brummel, M; Schutt, BS; Slabaugh, MB; Schuch, R; Spener, F Reaction mechanism of recombinant 3-oxoacyl-(acyl-carrier-protein) synthase III from Cuphea wrightii embryo, a fatty acid synthase type II condensing enzyme
BIOCHEM J. 2000; 345: 153-160. [OPEN ACCESS]
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1999

Buhlmann, C; Borchers, T; Pollak, M; Spener, F Fatty acid metabolism in human breast cancer cells (MCF7) transfected with heart-type fatty acid binding protein
MOL CELL BIOCHEM. MOLECULAR AND CELLULAR BIOCHEMISTRY; 199: 41-48.
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Mueller, PP; Schlenke, P; Nimtz, M; Conradt, HS; Hauser, H Recombinant glycoprotein product quality in proliferation-controlled BHK-21 cells.
Biotechnol Bioeng. 1999; 65(5):529-536
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Stepan, VM; Sawada, M; Todisco, A; Dickinson, CJ Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells.
Mol Med. 1999; 5(3):147-159 [OPEN ACCESS]
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Tiran, A; Tio, RA; Oostenveld, E; Harmsen, MC; Tiran, B; Den Heijer, P; Monnink, SH; Wilders-Truschnig, MM; The, TH Humoral immune response to human cytomegalovirus in patients undergoing percutaneous transluminal coronary angioplasty.
Clin Diagn Lab Immunol. 1999; 6(1):45-49 [OPEN ACCESS]
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Valenta, R; Vrtala, S; Focke-Tejkl, M; Bugajska-Schretter, M; Ball, T; Twardosz, A; Spitzauer, S; Grönlund, H; Kraft, D Genetically engineered and synthetic allergen derivatives: candidates for vaccination against type I allergy.
Biol Chem. 1999; 380(7-8):815-824
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1998

Bibel, M; Brettl, C; Gosslar, U; Kriegshäuser, G; Liebl, W Isolation and analysis of genes for amylolytic enzymes of the hyperthermophilic bacterium Thermotoga maritima.
FEMS Microbiol Lett. 1998; 158(1):9-15 [OPEN ACCESS]
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Scheib, H; Pleiss, J; Stadler, P; Kovac, A; Potthoff, AP; Haalck, L; Spener, F; Paltauf, F; Schmid, RD Rational design of Rhizopus oryzae lipase with modified stereoselectivity toward triradylglycerols.
Protein Eng. 1998; 11(8):675-682 [OPEN ACCESS]
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Schreiber, A; Specht, B; Pelsers, MM; Glatz, JF; Börchers, T; Spener, F Recombinant human heart-type fatty acid-binding protein as standard in immunochemical assays.
Clin Chem Lab Med. 1998; 36(5):283-288
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1997

Fedorov, AA; Ball, T; Mahoney, NM; Valenta, R; Almo, SC The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin.
Structure. 1997; 5(1):33-45 [OPEN ACCESS]
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Harmsen, MC; Heeringa, P; van der Geld, YM; Huitema, MG; Klimp, A; Tiran, A; Kallenberg, CG Recombinant proteinase 3 (Wegener's antigen) expressed in Pichia pastoris is functionally active and is recognized by patient sera.
Clin Exp Immunol. 1997; 110(2): 257-264. [OPEN ACCESS]
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Höfer, GF; Hohenthanner, K; Baumgartner, W; Groschner, K; Klugbauer, N; Hofmann, F; Romanin, C Intracellular Ca2+ inactivates L-type Ca2+ channels with a Hill coefficient of approximately 1 and an inhibition constant of approximately 4 microM by reducing channel's open probability.
Biophys J. 1997; 73(4):1857-1865 [OPEN ACCESS]
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Nielsen, LB; McCormick, SP; Pierotti, V; Tam, C; Gunn, MD; Shizuya, H; Young, SG Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine.
J Biol Chem. 1997; 272(47): 29752-29758. [OPEN ACCESS]
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1995

Förster, E; Dudler, T; Gmachl, M; Aberer, W; Urbanek, R; Suter, M Natural and recombinant enzymatically active or inactive bee venom phospholipase A2 has the same potency to release histamine from basophils in patients with Hymenoptera allergy.
J ALLERG CLIN IMMUNOL. 1995; 95: 1229-1235.
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1992

WAGNER, E; PLANK, C; ZATLOUKAL, K; COTTEN, M; BIRNSTIEL, ML Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.
Proc Natl Acad Sci U S A. 1992; 89(17):7934-7938 [OPEN ACCESS]
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