Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: RECOMBINANT PROTEINS - CHEMISTRY , . Treffer: 44

2017

Emmanouilidis, L; Schütz, U; Tripsianes, K; Madl, T; Radke, J; Rucktäschel, R; Wilmanns, M; Schliebs, W; Erdmann, R; Sattler, M Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19.
Nat Commun. 2017; 8(7):14635-14635 [OPEN ACCESS]
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2016

Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochim Biophys Acta. 2016; 1861(5):462-470 [OPEN ACCESS]
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Biundo, A; Hromic, A; Pavkov-Keller, T; Gruber, K; Quartinello, F; Haernvall, K; Perz, V; Arrell, MS; Zinn, M; Ribitsch, D; Guebitz, GM Characterization of a poly(butylene adipate-co-terephthalate)- hydrolyzing lipase from Pelosinus fermentans.
Appl Microbiol Biotechnol. 2016; 100(4): 1753-1764. [OPEN ACCESS]
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Janowski, R; Scanu, S; Niessing, D; Madl, T Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Acta Crystallogr F Struct Biol Commun. 2016; 72(Pt 10):743-749 [OPEN ACCESS]
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Krainer, FW; Gerstmann, MA; Darnhofer, B; Birner-Gruenberger, R; Glieder, A Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris.
J Biotechnol. 2016; 233(31):181-189 [OPEN ACCESS]
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Voith von Voithenberg, L; Sánchez-Rico, C; Kang, HS; Madl, T; Zanier, K; Barth, A; Warner, LR; Sattler, M; Lamb, DC Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proc Natl Acad Sci U S A. 2016; 113(46):E7169-E7175 [OPEN ACCESS]
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2015

Chromikova, V; Mader, A; Hofbauer, S; Göbl, C; Madl, T; Gach, JS; Bauernfried, S; Furtmüller, PG; Forthal, DN; Mach, L; Obinger, C; Kunert, R Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM.
Biochim Biophys Acta. 2015; 1854(10 Pt A):1536-1544 [OPEN ACCESS]
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Haslbeck, V; Eckl, JM; Drazic, A; Rutz, DA; Lorenz, OR; Zimmermann, K; Kriehuber, T; Lindemann, C; Madl, T; Richter, K The activity of protein phosphatase 5 towards native clients is modulated by the middle- and C-terminal domains of Hsp90.
Sci Rep. 2015; 5(4):17058-17058 [OPEN ACCESS]
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Perz, V; Zumstein, MT; Sander, M; Zitzenbacher, S; Ribitsch, D; Guebitz, GM Biomimetic Approach to Enhance Enzymatic Hydrolysis of the Synthetic Polyester Poly(1,4-butylene adipate): Fusing Binding Modules to Esterases.
Biomacromolecules. 2015; 16(12): 3889-3896.
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Sahu-Osen, A; Montero-Moran, G; Schittmayer, M; Fritz, K; Dinh, A; Chang, YF; McMahon, D; Boeszoermenyi, A; Cornaciu, I; Russell, D; Oberer, M; Carman, GM; Birner-Gruenberger, R; Brasaemle, DL CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization.
J Lipid Res. 2015; 56(1):109-121 [OPEN ACCESS]
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2014

Lorenz, OR; Freiburger, L; Rutz, DA; Krause, M; Zierer, BK; Alvira, S; Cuéllar, J; Valpuesta, JM; Madl, T; Sattler, M; Buchner, J Modulation of the Hsp90 chaperone cycle by a stringent client protein.
Mol Cell. 2014; 53(6): 941-953. [OPEN ACCESS]
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Sammar, M; Nisamblatt, S; Gonen, R; Huppertz, B; Gizurarson, S; Osol, G; Meiri, H The role of the carbohydrate recognition domain of placental protein 13 (PP13) in pregnancy evaluated with recombinant PP13 and the DelT221 PP13 variant.
PLoS One. 2014; 9(7):e102832-e102832 [OPEN ACCESS]
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2013

Müller, R; Gräwert, MA; Kern, T; Madl, T; Peschek, J; Sattler, M; Groll, M; Buchner, J High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Proc Natl Acad Sci U S A. 2013; 110(25): 10183-10188. [OPEN ACCESS]
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Walte, A; Rüben, K; Birner-Gruenberger, R; Preisinger, C; Bamberg-Lemper, S; Hilz, N; Bracher, F; Becker, W Mechanism of dual specificity kinase activity of DYRK1A.
FEBS J. 2013; 280(18):4495-4511 [OPEN ACCESS]
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2012

Rengachari, S; Bezerra, GA; Riegler-Berket, L; Gruber, CC; Sturm, C; Taschler, U; Boeszoermenyi, A; Dreveny, I; Zimmermann, R; Gruber, K; Oberer, M The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes.
Biochim Biophys Acta. 2012; 1821(7):1012-1021 [OPEN ACCESS]
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2010

Gruber, A; Cornaciu, I; Lass, A; Schweiger, M; Poeschl, M; Eder, C; Kumari, M; Schoiswohl, G; Wolinski, H; Kohlwein, SD; Zechner, R; Zimmermann, R; Oberer, M The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
J Biol Chem. 2010; 285(16): 12289-12298. [OPEN ACCESS]
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Ribitsch, D; Karl, W; Birner-Gruenberger, R; Gruber, K; Eiteljoerg, I; Remler, P; Wieland, S; Siegert, P; Maurer, KH; Schwab, H C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli.
J Biotechnol. 2010; 150(3):408-416
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2008

Göhler, A; Xiong, G; Paulsen, S; Trentmann, G; Maser, E Testosterone-inducible regulator is a kinase that drives steroid sensing and metabolism in Comamonas testosteroni.
J Biol Chem. 2008; 283(25):17380-17390 [OPEN ACCESS]
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Hermann, M; Kietzmann, MU; Ivancic, M; Zenzmaier, C; Luiten, RGM; Skranc, W; Wubbolts, M; Winkler, M; Birner-Gruenberger, R; Pichler, H; Schwab, H Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst.
J BIOTECHNOL. 2008; 133(3): 301-310.
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2006

Waratrujiwong, T; Krebs, B; Spener, F; Visoottiviseth, P Recombinant purple acid phosphatase isoform 3 from sweet potato is an enzyme with a diiron metal center.
FEBS J. 2006; 273(8):1649-1659
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Wiktor-Brown, DM; Hendricks, CA; Olipitz, W; Engelward, BP Age-dependent accumulation of recombinant cells in the mouse pancreas revealed by in situ fluorescence imaging.
Proc Natl Acad Sci U S A. 2006; 103(32):11862-11867 [OPEN ACCESS]
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2005

Batard, T; Didierlaurent, A; Chabre, H; Mothes, N; Bussières, L; Bohle, B; Couret, MN; Ball, T; Lemoine, P; Focks Tejkl, M; Chenal, A; Clément, G; Dupont, F; Valent, P; Krauth, MT; André, C; Valenta, R; Moingeon, P Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy.
Int Arch Allergy Immunol. 2005; 136(3):239-249
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Marget, M; Bohlsen, D; Davarnia, P; Yoo-Ott, K; Kabelitz, D; Skerra, A; Steinmann, J A HLA-Cw6 specific single-chain antibody fragment (scFv) recognizing a natural killer cell receptor epitope.
Mol Immunol. 2005; 42(5): 643-649.
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2004

Dobnig, H A review of teriparatide and its clinical efficacy in the treatment of osteoporosis.
EXPERT OPIN PHARMACOTHER. 2004; 5(5): 1153-1162.
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Naseri, JI; Truong, NT; Hörentrup, J; Kuballa, P; Vogel, A; Rompel, A; Spener, F; Krebs, B Porcine purple acid phosphatase: heterologous expression, characterization, and proteolytic analysis.
Arch Biochem Biophys. 2004; 432(1):25-36
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2003

Verhoeven, K; De Jonghe, P; Coen, K; Verpoorten, N; Auer-Grumbach, M; Kwon, JM; FitzPatrick, D; Schmedding, E; De Vriendt, E; Jacobs, A; Van Gerwen, V; Wagner, K; Hartung, HP; Timmerman, V Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy.
Am J Hum Genet. 2003; 72(3):722-727 [OPEN ACCESS]
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2002

Gutiérrez-González, LH; Ludwig, C; Hohoff, C; Rademacher, M; Hanhoff, T; Rüterjans, H; Spener, F; Lücke, C Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP).
Biochem J. 2002; 364(Pt 3):725-737 [OPEN ACCESS]
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Vogel, A; Börchers, T; Marcus, K; Meyer, HE; Krebs, B; Spener, F Heterologous expression and characterization of recombinant purple acid phosphatase from red kidney bean.
Arch Biochem Biophys. 2002; 401(2):164-172
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2001

Hrzenjak, A; Artl, A; Knipping, G; Kostner, G; Sattler, W; Malle, E Silent mutations in secondary Shine-Dalgarno sequences in the cDNA of human serum amyloid A4 promotes expression of recombinant protein in Escherichia coli.
Protein Eng. 2001; 14(12):949-952 [OPEN ACCESS]
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2000

Abbadi, A; Brummel, M; Schutt, BS; Slabaugh, MB; Schuch, R; Spener, F Reaction mechanism of recombinant 3-oxoacyl-(acyl-carrier-protein) synthase III from Cuphea wrightii embryo, a fatty acid synthase type II condensing enzyme
BIOCHEM J. 2000; 345: 153-160. [OPEN ACCESS]
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Abbadi, A; Brummel, M; Spener, F Knockout of the regulatory site of 3-ketoacyl-ACP synthase III enhances short- and medium-chain acyl-ACP synthesis.
Plant J. 2000; 24(1):1-9 [OPEN ACCESS]
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Gibb, GM; Pearce, J; Betts, JC; Lovestone, S; Hoffmann, MM; Maerz, W; Blackstock, WP; Anderton, BH Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3 beta identified by nano-electrospray mass spectrometry.
FEBS Lett. 2000; 485(2-3): 99-103.
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Hrzenjak, A; Frank, S; Maderegger, B; Sterk, H; Kostner, GM Apo(a)-kringle IV-type 6: expression in Escherichia coli, purification and in vitro refolding.
Protein Eng. 2000; 13(9):661-666 [OPEN ACCESS]
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Kepplinger, KJ; Kahr, H; Förstner, G; Sonnleitner, M; Schindler, H; Schmidt, T; Groschner, K; Soldatov, NM; Romanin, C A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels.
FEBS Lett. 2000; 477(3):161-169 [OPEN ACCESS]
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Zhai, J; Schmidt, AG; Hoit, BD; Kimura, Y; MacLennan, DH; Kranias, EG Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo.
J Biol Chem. 2000; 275(14): 10538-10544. [OPEN ACCESS]
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1999

Grabenhorst, E; Schlenke, P; Pohl, S; Nimtz, M; Conradt, HS Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells.
Glycoconj J. 1999; 16(2):81-97
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Hohoff, C; Börchers, T; Rüstow, B; Spener, F; van Tilbeurgh, H Expression, purification, and crystal structure determination of recombinant human epidermal-type fatty acid binding protein.
Biochemistry. 1999; 38(38):12229-12239
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1998

Scheib, H; Pleiss, J; Stadler, P; Kovac, A; Potthoff, AP; Haalck, L; Spener, F; Paltauf, F; Schmid, RD Rational design of Rhizopus oryzae lipase with modified stereoselectivity toward triradylglycerols.
Protein Eng. 1998; 11(8):675-682 [OPEN ACCESS]
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1997

Fedorov, AA; Ball, T; Mahoney, NM; Valenta, R; Almo, SC The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin.
Structure. 1997; 5(1):33-45 [OPEN ACCESS]
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Frank, S; Kostner, GM The role of apo-(a) kringle-IVs in the assembly of lipoprotein-(a).
Protein Eng. 1997; 10(3):291-298 [OPEN ACCESS]
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Höfer, GF; Hohenthanner, K; Baumgartner, W; Groschner, K; Klugbauer, N; Hofmann, F; Romanin, C Intracellular Ca2+ inactivates L-type Ca2+ channels with a Hill coefficient of approximately 1 and an inhibition constant of approximately 4 microM by reducing channel's open probability.
Biophys J. 1997; 73(4):1857-1865 [OPEN ACCESS]
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Jenne, DE; Fröhlich, L; Hummel, AM; Specks, U Cloning and functional expression of the murine homologue of proteinase 3: implications for the design of murine models of vasculitis.
FEBS Lett. 1997; 408(2):187-190
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Rauch, U; Clement, A; Retzler, C; Fröhlich, L; Fässler, R; Göhring, W; Faissner, A Mapping of a defined neurocan binding site to distinct domains of tenascin-C.
J Biol Chem. 1997; 272(43):26905-26912 [OPEN ACCESS]
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1995

Rolf, B; Oudenampsen-Krüger, E; Börchers, T; Faergeman, NJ; Knudsen, J; Lezius, A; Spener, F Analysis of the ligand binding properties of recombinant bovine liver-type fatty acid binding protein.
Biochim Biophys Acta. 1995; 1259(3):245-253
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