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Publikationen

Suchbegriffe: PROTO-ONCOGENE PROTEINS - GENETICS , . Treffer: 52

2016

Wiesner, T; Kutzner, H; Cerroni, L; Mihm, MC; Busam, KJ; Murali, R Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapy.
Pathology. 2016; 48(2):113-131 Doi: 10.1016/j.pathol.2015.12.007 [OPEN ACCESS]
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2015

Crescenzo, R; Abate, F; Lasorsa, E; Tabbo', F; Gaudiano, M; Chiesa, N; Di Giacomo, F; Spaccarotella, E; Barbarossa, L; Ercole, E; Todaro, M; Boi, M; Acquaviva, A; Ficarra, E; Novero, D; Rinaldi, A; Tousseyn, T; Rosenwald, A; Kenner, L; Cerroni, L; Tzankov, A; Ponzoni, M; Paulli, M; Weisenburger, D; Chan, WC; Iqbal, J; Piris, MA; Zamo', A; Ciardullo, C; Rossi, D; Gaidano, G; Pileri, S; Tiacci, E; Falini, B; Shultz, LD; Mevellec, L; Vialard, JE; Piva, R; Bertoni, F; Rabadan, R; Inghirami, G; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium “Genetics-Driven Targeted Management of Lymphoid Malignancies” Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Cancer Cell. 2015; 27(4):516-532 Doi: 10.1016/j.ccell.2015.03.006 [OPEN ACCESS]
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Heitzer, E; Ulz, P; Geigl, JB Circulating tumor DNA as a liquid biopsy for cancer.
Clin Chem. 2015; 61(1):112-123 Doi: 10.1373/clinchem.2014.222679 [OPEN ACCESS]
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Kaczirek, K; Ciuleanu, TE; Vrbanec, D; Marton, E; Messinger, D; Liegl-Atzwanger, B; Wrba, F; Knittelfelder, R; Lindner, E; Zielinski, CC; Streubel, B; Brodowicz, T FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study.
Clin Colorectal Cancer. 2015; 14(2):91-98 Doi: 10.1016/j.clcc.2014.12.003
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Leithner, K; Hrzenjak, A; Trötzmüller, M; Moustafa, T; Köfeler, HC; Wohlkoenig, C; Stacher, E; Lindenmann, J; Harris, AL; Olschewski, A; Olschewski, H PCK2 activation mediates an adaptive response to glucose depletion in lung cancer.
Oncogene. 2015; 34(8):1044-1050 Doi: 10.1038/onc.2014.47
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Zopf, A; Raim, R; Danzer, M; Niklas, N; Spilka, R; Pröll, J; Gabriel, C; Nechansky, A; Roucka, M Introduction of the hybcell-based compact sequencing technology and comparison to state-of-the-art methodologies for KRAS mutation detection.
Biotechniques. 2015; 58(3):126-134 Doi: 10.2144/000114264 [OPEN ACCESS]
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2014

Pichler, M; Calin, GA Long noncoding RNA in neuroblastoma: new light on the (old) N-Myc story.
J Natl Cancer Inst. 2014; 106(7): Doi: 10.1093/jnci/dju150 [OPEN ACCESS]
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Pichler, M; Winter, E; Ress, AL; Bauernhofer, T; Gerger, A; Kiesslich, T; Lax, S; Samonigg, H; Hoefler, G miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor.
J Clin Pathol. 2014; 67(3):198-203 Doi: 10.1136/jclinpath-2013-201904
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Rau, TT; Agaimy, A; Gehoff, A; Geppert, C; Jung, K; Knobloch, K; Langner, C; Lugli, A; Groenbus-Lurkin, I; Nagtegaal, ID; Rüschoff, J; Saegert, X; Sarbia, M; Schneider-Stock, R; Vieth, M; Zwarthoff, EC; Hartmann, A Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics.
Virchows Arch. 2014; 464(6):663-672 Doi: 10.1007/s00428-014-1569-7
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2013

Buxhofer-Ausch, V; Ausch, C; Zeillinger, R; Oberkanins, C; Dandachi, N; Reiner-Concin, A; Kriegshäuser, G Duplex reverse-hybridization assay for the simultaneous detection of KRAS/BRAF mutations in FFPE-extracted genomic DNA from colorectal cancer specimens.
Dis Markers. 2013; 34(3):171-177 Doi: 10.3233/DMA-120960 [OPEN ACCESS]
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Dijkstra, JR; Heideman, DA; Meijer, GA; Boers, JE; 't Hart, NA; Diebold, J; Hirschmann, A; Hoefler, G; Winter, G; Miltenberger-Miltenyi, G; Pereira, SV; Richman, SD; Quirke, P; Rouleau, EL; Guinebretiere, JM; Tejpar, S; Biesmans, B; van Krieken, JH KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance.
Virchows Arch. 2013; 462(1):39-46 Doi: 10.1007/s00428-012-1356-2
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Setaffy, L; Högenauer, C; Lemmerer, M; Langner, C Large serrated polyp with KRAS mutation in inflammatory bowel disease: a "nondysplastic dysplasia-associated lesion or mass (DALM)"?
Endoscopy. 2013; 45 Suppl 2 UCTN(19):E235-E236 Doi: 10.1055/s-0033-1344321 (- Case Report) [OPEN ACCESS]
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Staber, PB; Zhang, P; Ye, M; Welner, RS; Nombela-Arrieta, C; Bach, C; Kerenyi, M; Bartholdy, BA; Zhang, H; Alberich-Jorda, M; Lee, S; Yang, H; Ng, F; Zhang, JY; Leddin, M; Silberstein, LE; Hoefler, G; Orkin, SH; Gottgens, B; Rosenbauer, F; Huang, G; Tenen, DG; Sustained PU.1 Levels Balance Cell-Cycle Regulators to Prevent Exhaustion of Adult Hematopoietic Stem Cells.
MOL CELL. 2013; 49(5): 934-946. Doi: 10.1016/j.molcel.2013.01.007 [OPEN ACCESS]
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Zebisch, A; Hoefler, G; Quehenberger, F; Wölfler, A; Sill, H Mutant DNMT3A in acute myeloid leukemia: guilty of inducing genetic instability?
Leukemia. 2013; 27(8): 1777-1778. Doi: 10.1038/leu.2013.48 [OPEN ACCESS]
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2012

Bauer, T; Zagórska, A; Jurkin, J; Yasmin, N; Köffel, R; Richter, S; Gesslbauer, B; Lemke, G; Strobl, H Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis.
J Exp Med. 2012; 209(11):2033-2047 Doi: 10.1084/jem.20120493 [OPEN ACCESS]
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Dijkstra, JR; Opdam, FJ; Boonyaratanakornkit, J; Schönbrunner, ER; Shahbazian, M; Edsjö, A; Hoefler, G; Jung, A; Kotsinas, A; Gorgoulis, VG; Lpez-Ros, F; de Stricker, K; Rouleau, E; Biesmans, B; van Krieken, JH Implementation of formalin-fixed, paraffin-embedded cell line pellets as high-quality process controls in quality assessment programs for KRAS mutation analysis.
J Mol Diagn. 2012; 14(3):187-191 Doi: 10.1016/j.jmoldx.2012.01.002 [OPEN ACCESS]
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Pichler, M; Winter, E; Stotz, M; Eberhard, K; Samonigg, H; Lax, S; Hoefler, G; Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer.
Br J Cancer. 2012; 106(11):1826-1832 Doi: 10.1038/bjc.2012.175 [OPEN ACCESS]
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Schroll, A; Eller, K; Feistritzer, C; Nairz, M; Sonnweber, T; Moser, PA; Rosenkranz, AR; Theurl, I; Weiss, G Lipocalin 2 ameliorates granulocyte functionality.
Eur J Immunol. 2012; 42(12):3346-3357 Doi: 10.1002/eji.201142351 [OPEN ACCESS]
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van Krieken, JH; Hoefler, G The times have changed: molecular pathology is here to stay. A commentary on: analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma, by Lee et al. In this issue.
VIRCHOWS ARCH. 2012; 460(2): 129-130. Doi: 10.1007/s00428-012-1197-z [OPEN ACCESS]
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2011

Betge, J; Pollheimer, MJ; Schlemmer, A; Hoefler, G; Langner, C Gastric cancer and concomitant renal cancer: a systematic immunohistochemical and molecular analysis.
Oncol Rep. 2011; 26(3):567-575 Doi: 10.3892/or.2011.1346 [OPEN ACCESS]
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Jahn, SW; Winter, G; Stacher, E; Halbwedl, I; Gattenlöhner, S; Stockinger, R; Spreitzer, S; Waldispuehl-Geigl, J; Geigl, JB; Offner, F; Hoefler, G Multiple intratumoral KRAS mutations can clonally segregate to different lymph node metastases in colon cancer.
Histopathology. 2011; 59(2): 342-345. Doi: 10.1111/j.1365-2559.2011.03902.x (- Case Report)
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Kohlmann, A; Klein, HU; Weissmann, S; Bresolin, S; Chaplin, T; Cuppens, H; Haschke-Becher, E; Garicochea, B; Grossmann, V; Hanczaruk, B; Hebestreit, K; Gabriel, C; Iacobucci, I; Jansen, JH; te Kronnie, G; van de Locht, L; Martinelli, G; McGowan, K; Schweiger, MR; Timmermann, B; Vandenberghe, P; Young, BD; Dugas, M; Haferlach, T The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.
Leukemia. 2011; 25(12): 1840-1848. Doi: 10.1038/leu.2011.155 [OPEN ACCESS]
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Kriegshäuser, G; Auner, V; Schuster, E; Holzer, B; Oberkanins, C; Horvat, R; Speiser, P; Zeillinger, R KRAS mutation analysis in genomic DNA isolated from formalin-fixed paraffin-embedded ovarian tissue: evaluation of a strip-based reverse-hybridisation assay.
J Clin Pathol. 2011; 64(3): 252-256. Doi: 10.1136/jcp.2010.081414
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Kriegshäuser, G; Fabjani, G; Ziegler, B; Zöchbauer-Müller, S; End, A; Zeillinger, R Biochip-based detection of KRAS mutation in non-small cell lung cancer.
Int J Mol Sci. 2011; 12(12): 8530-8538. Doi: 10.3390/ijms12128530 [OPEN ACCESS]
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2010

Jurkin, J; Schichl, YM; Koeffel, R; Bauer, T; Richter, S; Konradi, S; Gesslbauer, B; Strobl, H miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation.
J Immunol. 2010; 184(9):4955-4965 Doi: 10.4049/jimmunol.0903021 [OPEN ACCESS]
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Weeraratna, AT; Houben, R; O'Connell, MP; Becker, JC Lack of Wnt5A expression in Merkel cell carcinoma.
Arch Dermatol. 2010; 146(1):88-89 Doi: 10.1001/archdermatol.2009.348 [OPEN ACCESS]
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Will, B; Siddiqi, T; Alberich Jordà, M; Shimamura, T; Luptakova, K; Staber, PB; Costa, DB; Steidl, U; Tenen, DG; Kobayashi, S Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells.
Blood. 2010; 115(14):2901-2909 Doi: 10.1182/blood-2009-03-209544 [OPEN ACCESS]
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Winder, T; Zhang, W; Yang, D; Ning, Y; Bohanes, P; Gerger, A; Wilson, P; Pohl, A; Mauro, DJ; Langer, C; Rowinsky, EK; Lenz, HJ Germline Polymorphisms in Genes Involved in the IGF1 Pathway Predict Efficacy of Cetuximab in Wild-type KRAS mCRC Patients.
Clin Cancer Res. 2010; 16(22):5591-5602 Doi: 10.1158/1078-0432.CCR-10-2092 [OPEN ACCESS]
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2009

Auner, V; Kriegshäuser, G; Tong, D; Horvat, R; Reinthaller, A; Mustea, A; Zeillinger, R KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay.
BMC Cancer. 2009; 9(1): 111-111. Doi: 10.1186/1471-2407-9-111 [OPEN ACCESS]
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Ausch, C; Buxhofer-Ausch, V; Oberkanins, C; Holzer, B; Minai-Pour, M; Jahn, S; Dandachi, N; Zeillinger, R; Kriegshäuser, G Sensitive detection of KRAS mutations in archived formalin-fixed paraffin-embedded tissue using mutant-enriched PCR and reverse-hybridization.
J Mol Diagn. 2009; 11(6):508-513 Doi: 10.2353/jmoldx.2009.090022 [OPEN ACCESS]
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Pfragner, R; Behmel, A; Höger, H; Beham, A; Ingolic, E; Stelzer, I; Svejda, B; Moser, VA; Obenauf, AC; Siegl, V; Haas, O; Niederle, B Establishment and characterization of three novel cell lines - P-STS, L-STS, H-STS - derived from a human metastatic midgut carcinoid.
ANTICANCER RES. 2009; 29(6): 1951-1961. [OPEN ACCESS]
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2008

Schulz, AL; Albrecht, B; Arici, C; van der Burgt, I; Buske, A; Gillessen-Kaesbach, G; Heller, R; Horn, D; Hübner, CA; Korenke, GC; König, R; Kress, W; Krüger, G; Meinecke, P; Mücke, J; Plecko, B; Rossier, E; Schinzel, A; Schulze, A; Seemanova, E; Seidel, H; Spranger, S; Tuysuz, B; Uhrig, S; Wieczorek, D; Kutsche, K; Zenker, M Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome.
Clin Genet. 2008; 73(1):62-70 Doi: 10.1111/j.1399-0004.2007.00931.x
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van Krieken, JH; Jung, A; Kirchner, T; Carneiro, F; Seruca, R; Bosman, FT; Quirke, P; Fléjou, JF; Plato Hansen, T; de Hertogh, G; Jares, P; Langner, C; Hoefler, G; Ligtenberg, M; Tiniakos, D; Tejpar, S; Bevilacqua, G; Ensari, A KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program.
Virchows Arch. 2008; 453(5): 417-431. Doi: 10.1007/s00428-008-0665-y [OPEN ACCESS]
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2006

Tschernutter, M; Jenkins, SA; Waseem, NH; Saihan, Z; Holder, GE; Bird, AC; Bhattacharya, SS; Ali, RR; Webster, AR Clinical characterisation of a family with retinal dystrophy caused by mutation in the Mertk gene.
Br J Ophthalmol. 2006; 90(6): 718-723. Doi: 10.1136/bjo.2005.084897 [OPEN ACCESS]
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2005

Tschernutter, M; Schlichtenbrede, FC; Howe, S; Balaggan, KS; Munro, PM; Bainbridge, JW; Thrasher, AJ; Smith, AJ; Ali, RR Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy.
Gene Ther. 2005; 12(8): 694-701. Doi: 10.1038/sj.gt.3302460 [OPEN ACCESS]
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2004

Weltermann, A; Fonatsch, C; Haas, OA; Greinix, HT; Kahls, P; Mitterbauer, G; Jäger, U; Kainz, B; Geissler, K; Valent, P; Sperr, WR; Knöbl, P; Schwarzinger, I; Gleiss, A; Lechner, K Impact of cytogenetics on the prognosis of adults with de novo AML in first relapse.
Leukemia. 2004; 18(2): 293-302. Doi: 10.1038/sj.leu.2403243 [OPEN ACCESS]
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2003

Weinhäusel, A; Behmel, A; Ponder, BA; Haas, OA; Niederle, B; Gessl, A; Vierhapper, H; Pfragner, R Long-term follow up of a sporadic unilateral pheochromocytoma revealing multiple endocrine neoplasia MEN2A-2 in an elderly woman.
Endocr Pathol. 2003; 14(4):375-382 Doi: 10.1385%2FEP%3A14%3A4%3A375 (- Case Report)
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2002

Maschek, W; Pichler, R; Rieger, R; Weinhäusel, A; Berg, J A new identified germline mutation of the RET proto-oncogene responsible for familial medullary thyroid carcinoma in co-existence with a hyperfunctioning autonomous nodule.
Clin Endocrinol (Oxf). 2002; 56(6):823-823 Doi: 10.1046/j.1365-2265.2002.t01-1-01538.x (- Case Report)
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Thonhofer, R; Maercker, C; Popper, HH Expression of sarcoidosis related genes in lung lavage cells.
Sarcoidosis Vasc Diffuse Lung Dis. 2002; 19(1):59-65
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1999

Dahia, PL; Aguiar, RC; Alberta, J; Kum, JB; Caron, S; Sill, H; Marsh, DJ; Ritz, J; Freedman, A; Stiles, C; Eng, C PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies.
Hum Mol Genet. 1999; 8(2):185-193 Doi: 10.1093%2Fhmg%2F8.2.185 [OPEN ACCESS]
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Stepan, VM; Sawada, M; Todisco, A; Dickinson, CJ Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells.
Mol Med. 1999; 5(3):147-159 Doi: 10.1007/BF03402058 [OPEN ACCESS]
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1998

Ligr, M; Madeo, F; Fröhlich, E; Hilt, W; Fröhlich, KU; Wolf, DH Mammalian Bax triggers apoptotic changes in yeast.
FEBS Lett. 1998; 438(1-2):61-65 Doi: 10.1016/S0014-5793(98)01227-7
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Pammer, J; Weninger, W; Hulla, H; Mazal, P; Horvat, R Expression of regulatory apoptotic proteins in peripheral giant cell granulomas and lesions containing osteoclast-like giant cells.
J Oral Pathol Med. 1998; 27(6):267-271 Doi: 10.1111/j.1600-0714.1998.tb01954.x
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Pfragner, R; Behmel, A; Smith, DP; Ponder, BA; Wirnsberger, G; Rinner, I; Porta, S; Henn, T; Niederle, B First continuous human pheochromocytoma cell line: KNA. Biological, cytogenetic and molecular characterization of KNA cells.
J Neurocytol. 1998; 27(3):175-186 Doi: 10.1023%2FA%3A1006959625068
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Zoubek, A; Ladenstein, R; Windhager, R; Amann, G; Fischmeister, G; Kager, L; Jugovic, D; Ambros, PF; Gadner, H; Kovar, H Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT-PCR: a preliminary evaluation.
Int J Cancer. 1998; 79(1):56-60 Doi: 10.1002/(SICI)1097-0215(19980220)79:1<56::AID-IJC11>3.0.CO;2-F
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1995

Cerroni, L; Soyer, HP; Kerl, H bcl-2 protein expression in cutaneous malignant melanoma and benign melanocytic nevi.
Am J Dermatopathol. 1995; 17(1):7-11 Doi: 10.1097/00000372-199502000-00002
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Chetty, R; Cerroni, L; Pulford, K; Giatromanolaki, A; Biddolph, S; Kaklamanis, L; Gatter, K TAL1 gene deletions and TAL1 protein expression in sporadic melanoma.
MELANOMA RES. 1995; 5: 251-254. Doi: 10.1097/00008390-199508000-00007
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Klintschar, M Validation of the STR system FES/FPS for forensic purposes in an Austrian population sample.
Int J Legal Med. 1995; 108(3):162-164 Doi: 10.1007%2FBF01844830
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1994

Aringer, M; Wintersberger, W; Steiner, CW; Kiener, H; Presterl, E; Jaeger, U; Smolen, JS; Graninger, WB High levels of bcl-2 protein in circulating T lymphocytes, but not B lymphocytes, of patients with systemic lupus erythematosus.
Arthritis Rheum. 1994; 37(10):1423-1430 Doi: 10.1002/art.1780371004
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Kovar, H; Zoubek, A; Pfleiderer, C; Jug, G; Auinger, A; Aryee, D; Ambros, PF; Salzer-Kuntschik, M; Amann, G; Windhager, R The EWS gene rearrangement in Ewing tumors: key to the disease
Klin Padiatr. 1994; 206(4): 196-200. Doi: 10.1055/s-2008-1046605
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