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Publikationen

Suchbegriffe: PROTEIN BINDING - , . Treffer: 135

2020

Greilberger, J; Herwig, R Vitamin D - Deglycosylated Vitamin D Binding Protein Dimer: Positive Synergistic Effects on Recognition, Activation, Phagocytosis and Oxidative Stress on Macrophages.
CLIN LAB. 2020; 66(1): Doi: 10.7754/Clin.Lab.2019.191121
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Pogenberg, V; Ballesteros-Álvarez, J; Schober, R; Sigvaldadóttir, I; Obarska-Kosinska, A; Milewski, M; Schindl, R; Ögmundsdóttir, MH; Steingrímsson, E; Wilmanns, M Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif.
Nucleic Acids Res. 2020; 48(2):934-948 Doi: 10.1093/nar/gkz1104 [OPEN ACCESS]
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Spreitzer, E; Usluer, S; Madl, T Probing Surfaces in Dynamic Protein Interactions.
J Mol Biol. 2020; 432(9):2949-2972 Doi: 10.1016/j.jmb.2020.02.032 [OPEN ACCESS]
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2019

Krysko, O; Teufelberger, A; Van Nevel, S; Krysko, DV; Bachert, C Protease/antiprotease network in allergy: The role of Staphylococcus aureus protease-like proteins.
Allergy. 2019; 74(11): 2077-2086. Doi: 10.1111/all.13783
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Sánchez-Murcia, PA; Mills, A; Cortés-Cabrera, Á; Gago, F Unravelling the covalent binding of zampanolide and taccalonolide AJ to a minimalist representation of a human microtubule.
J Comput Aided Mol Des. 2019; 33(7):627-644 Doi: 10.1007/s10822-019-00208-w
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Schopf, FH; Huber, EM; Dodt, C; Lopez, A; Biebl, MM; Rutz, DA; Mühlhofer, M; Richter, G; Madl, T; Sattler, M; Groll, M; Buchner, J The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
MOL CELL. 2019; 74(1): 73-87. Doi: 10.1016/j.molcel.2019.02.011 [OPEN ACCESS]
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2018

Biasin, V; Wygrecka, M; Bärnthaler, T; Jandl, K; Jain, PP; Bálint, Z; Kovacs, G; Leitinger, G; Kolb-Lenz, D; Kornmueller, K; Peters, F; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Becker-Pauly, C; Kwapiszewska, G Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Thromb Haemost. 2018; 118(10):1790-1802 Doi: 10.1055/s-0038-1670657
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Hofweber, M; Hutten, S; Bourgeois, B; Spreitzer, E; Niedner-Boblenz, A; Schifferer, M; Ruepp, MD; Simons, M; Niessing, D; Madl, T; Dormann, D Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell. 2018; 173(3):706-719 Doi: 10.1016/j.cell.2018.03.004 [OPEN ACCESS]
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2017

Emmanouilidis, L; Schütz, U; Tripsianes, K; Madl, T; Radke, J; Rucktäschel, R; Wilmanns, M; Schliebs, W; Erdmann, R; Sattler, M Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19.
Nat Commun. 2017; 8(7):14635-14635 Doi: 10.1038/ncomms14635 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 Doi: 10.1002/1873-3468.12845 [OPEN ACCESS]
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Geuens, T; De Winter, V; Rajan, N; Achsel, T; Mateiu, L; Almeida-Souza, L; Asselbergh, B; Bouhy, D; Auer-Grumbach, M; Bagni, C; Timmerman, V Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
Acta Neuropathol Commun. 2017; 5(1):5-5 Doi: 10.1186/s40478-016-0407-3 [OPEN ACCESS]
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Li, MX; Tan, IKL; Ma, SB; Hockings, C; Kratina, T; Dengler, MA; Alsop, AE; Kluck, RM; Dewson, G BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove.
Proc Natl Acad Sci U S A. 2017; 114(29):7629-7634 Doi: 10.1073/pnas.1702453114 [OPEN ACCESS]
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Oliva, C; Sánchez-Murcia, PA; Rico, E; Bravo, A; Menéndez, M; Gago, F; Jiménez-Ruiz, A Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.
Nucleic Acids Res. 2017; 45(15):9030-9045 Doi: 10.1093/nar/gkx629 [OPEN ACCESS]
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Sánchez-Murcia, PA; Cortés-Cabrera, Á; Gago, F Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.
J Comput Aided Mol Des. 2017; 31(10):915-928 Doi: 10.1007/s10822-017-0066-x
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Stentzel, S; Teufelberger, A; Nordengrün, M; Kolata, J; Schmidt, F; van Crombruggen, K; Michalik, S; Kumpfmüller, J; Tischer, S; Schweder, T; Hecker, M; Engelmann, S; Völker, U; Krysko, O; Bachert, C; Bröker, BM Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus.
J Allergy Clin Immunol. 2017; 139(2): 492-500. Doi: 10.1016/j.jaci.2016.03.045
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Wallace, PW; Haernvall, K; Ribitsch, D; Zitzenbacher, S; Schittmayer, M; Steinkellner, G; Gruber, K; Guebitz, GM; Birner-Gruenberger, R PpEst is a novel PBAT degrading polyesterase identified by proteomic screening of Pseudomonas pseudoalcaligenes.
Appl Microbiol Biotechnol. 2017; 101(6):2291-2303 Doi: 10.1007/s00253-016-7992-8 [OPEN ACCESS]
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Winter, MP; Kleber, ME; Koller, L; Sulzgruber, P; Scharnagl, H; Delgado, G; Goliasch, G; März, W; Niessner, A Prognostic significance of tPA/PAI-1 complex in patients with heart failure and preserved ejection fraction.
Thromb Haemost. 2017; 117(3):471-478 Doi: 10.1160/TH16-08-0600
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2016

Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochim Biophys Acta. 2016; 1861(5):462-470 Doi: 10.1016/j.bbalip.2016.02.005 [OPEN ACCESS]
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Dernayka, L; Rauch, N; Jarboui, MA; Zebisch, A; Texier, Y; Horn, N; Romano, D; Gloeckner, CJ; Kriegsheim, Av; Ueffing, M; Kolch, W; Boldt, K Autophosphorylation on S614 inhibits the activity and the transforming potential of BRAF.
Cell Signal. 2016; 28(9):1432-1439 Doi: 10.1016/j.cellsig.2016.06.016
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Eloot, S; Schneditz, D; Cornelis, T; Van Biesen, W; Glorieux, G; Dhondt, A; Kooman, J; Vanholder, R Protein-Bound Uremic Toxin Profiling as a Tool to Optimize Hemodialysis.
PLoS One. 2016; 11(1):e0147159-e0147159 Doi: 10.1371/journal.pone.0147159 [OPEN ACCESS]
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Grün, NG; Strohmeier, K; Moreno-Viedma, V; Le Bras, M; Landlinger, C; Zeyda, K; Wanko, B; Leitner, L; Staffler, G; Zeyda, M; Stulnig, TM Peptide-based vaccination against OPN integrin binding sites does not improve cardio-metabolic disease in mice.
Immunol Lett. 2016; 179(11):85-94 Doi: 10.1016/j.imlet.2016.09.006 [OPEN ACCESS]
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Herrada, I; Bourgeois, B; Samson, C; Buendia, B; Worman, HJ; Zinn-Justin, S Purification and Structural Analysis of LEM-Domain Proteins.
Methods Enzymol. 2016; 569(4):43-61 Doi: 10.1016/bs.mie.2015.07.008
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Mitterer, V; Gantenbein, N; Birner-Gruenberger, R; Murat, G; Bergler, H; Kressler, D; Pertschy, B Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1.
Sci Rep. 2016; 6(24):36714-36714 Doi: 10.1038/srep36714 [OPEN ACCESS]
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Scharinger, B; Messner, B; Türkcan, A; Schuster, D; Vuorinen, A; Pitterl, F; Heinz, K; Arnhard, K; Laufer, G; Grimm, M; Stuppner, H; Oberacher, H; Eller, P; Ritsch, A; Bernhard, D Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice.
J Mol Cell Cardiol. 2016; 99(7):35-46 Doi: 10.1016/j.yjmcc.2016.08.003 [OPEN ACCESS]
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Voith von Voithenberg, L; Sánchez-Rico, C; Kang, HS; Madl, T; Zanier, K; Barth, A; Warner, LR; Sattler, M; Lamb, DC Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proc Natl Acad Sci U S A. 2016; 113(46):E7169-E7175 Doi: 10.1073/pnas.1605873113 [OPEN ACCESS]
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Weber, J; Bao, H; Hartlmüller, C; Wang, Z; Windhager, A; Janowski, R; Madl, T; Jin, P; Niessing, D Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha.
Elife. 2016; 5(7): Doi: 10.7554/eLife.11297 [OPEN ACCESS]
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Werten, S; Kohler, C; Bayer, NJ; Steinmetz, I; Hinrichs, W Structural analysis and knock-out of a Burkholderia pseudomallei homolog of the eukaryotic transcription coactivator PC4.
Gene. 2016; 577(2): 140-147. Doi: 10.1016/j.gene.2015.11.037
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2015

Gerlza, T; Winkler, S; Atlic, A; Zankl, C; Konya, V; Kitic, N; Strutzmann, E; Knebl, K; Adage, T; Heinemann, A; Weis, R; Kungl, AJ Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity.
Protein Eng Des Sel. 2015; 28(8):231-240 Doi: 10.1093/protein/gzv025 [OPEN ACCESS]
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Gersch, M; Famulla, K; Dahmen, M; Göbl, C; Malik, I; Richter, K; Korotkov, VS; Sass, P; Rübsamen-Schaeff, H; Madl, T; Brötz-Oesterhelt, H; Sieber, SA AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.
Nat Commun. 2015; 6(2):6320-6320 Doi: 10.1038/ncomms7320 [OPEN ACCESS]
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Haslbeck, V; Eckl, JM; Drazic, A; Rutz, DA; Lorenz, OR; Zimmermann, K; Kriehuber, T; Lindemann, C; Madl, T; Richter, K The activity of protein phosphatase 5 towards native clients is modulated by the middle- and C-terminal domains of Hsp90.
Sci Rep. 2015; 5(4):17058-17058 Doi: 10.1038/srep17058 [OPEN ACCESS]
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Koos, B; Cane, G; Grannas, K; Löf, L; Arngården, L; Heldin, J; Clausson, CM; Klaesson, A; Hirvonen, MK; de Oliveira, FM; Talibov, VO; Pham, NT; Auer, M; Danielson, UH; Haybaeck, J; Kamali-Moghaddam, M; Söderberg, O Proximity-dependent initiation of hybridization chain reaction.
Nat Commun. 2015; 6(6):7294-7294 Doi: 10.1038/ncomms8294 [OPEN ACCESS]
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Krstic, J; Obradovic, H; Kukolj, T; Mojsilovic, S; Okic-Dordevic, I; Bugarski, D; Santibanez, JF An Overview of Interleukin-17A and Interleukin-17 Receptor A Structure, Interaction and Signaling.
Protein Pept Lett. 2015; 22(7): 570-578. Doi: 10.2174/0929866522666150520145554
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Meyer, NH; Mayerhofer, H; Tripsianes, K; Blindow, S; Barths, D; Mewes, A; Weimar, T; Köhli, T; Bade, S; Madl, T; Frey, A; Haas, H; Mueller-Dieckmann, J; Sattler, M; Schramm, G A Crystallin Fold in the Interleukin-4-inducing Principle of Schistosoma mansoni Eggs (IPSE/α-1) Mediates IgE Binding for Antigen-independent Basophil Activation.
J Biol Chem. 2015; 290(36): 22111-22126. Doi: 10.1074/jbc.M115.675066 [OPEN ACCESS]
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Wang, SR; Yang, CG; Sánchez-Murcia, PA; Snyder, JP; Yan, N; Sáez-Calvo, G; Díaz, JF; Gago, F; Fang, WS Restoration of Microtubule Interaction and Cytotoxicity in D-seco Taxanes upon Incorporation of 20-Hydroxymethyl-4-allyloxy Groups.
Org Lett. 2015; 17(24):6098-6101 Doi: 10.1021/acs.orglett.5b03119
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Wang, T; Grabski, R; Sztul, E; Hay, JC p115-SNARE interactions: a dynamic cycle of p115 binding monomeric SNARE motifs and releasing assembled bundles.
Traffic. 2015; 16(2):148-171 Doi: 10.1111/tra.12242 [OPEN ACCESS]
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2014

Baumgartner, W; Weth, A; Gutberlet, J; Harms, G; Groschner, K Localization of VE-cadherin in plasmalemmal cholesterol rich microdomains and the effects of cholesterol depletion on VE-cadherin mediated cell-cell adhesion.
Biochim Biophys Acta. 2014; 1841(12): 1725-1732. Doi: 10.1016/j.bbalip.2014.08.016
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Canales, A; Nieto, L; Rodríguez-Salarichs, J; Sánchez-Murcia, PA; Coderch, C; Cortés-Cabrera, A; Paterson, I; Carlomagno, T; Gago, F; Andreu, JM; Altmann, KH; Jiménez-Barbero, J; Díaz, JF Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches.
ACS Chem Biol. 2014; 9(4):1033-1043 Doi: 10.1021/cb400673h
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Farrell, CJ; Soldo, J; McWhinney, B; Bandodkar, S; Herrmann, M Impact of assay design on test performance: lessons learned from 25-hydroxyvitamin D.
Clin Chem Lab Med. 2014; 52(11):1579-1587 Doi: 10.1515/cclm-2014-0111
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Helm, JR; Bentley, M; Thorsen, KD; Wang, T; Foltz, L; Oorschot, V; Klumperman, J; Hay, JC Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium.
J Biol Chem. 2014; 289(34):23609-23628 Doi: 10.1074/jbc.M114.561829 [OPEN ACCESS]
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Huang, JR; Warner, LR; Sanchez, C; Gabel, F; Madl, T; Mackereth, CD; Sattler, M; Blackledge, M Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain splicing factor U2AF65: a combined NMR and SAXS study.
J Am Chem Soc. 2014; 136(19):7068-7076 Doi: 10.1021/ja502030n
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Liu, L; Huang, C; He, ZG A TetR family transcriptional factor directly regulates the expression of a 3-methyladenine DNA glycosylase and physically interacts with the enzyme to stimulate its base excision activity in Mycobacterium bovis BCG.
J Biol Chem. 2014; 289(13):9065-9075 Doi: 10.1074/jbc.M113.528919 [OPEN ACCESS]
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Lorenz, OR; Freiburger, L; Rutz, DA; Krause, M; Zierer, BK; Alvira, S; Cuéllar, J; Valpuesta, JM; Madl, T; Sattler, M; Buchner, J Modulation of the Hsp90 chaperone cycle by a stringent client protein.
Mol Cell. 2014; 53(6): 941-953. Doi: 10.1016/j.molcel.2014.02.003 [OPEN ACCESS]
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Maraschi, A; Ciammola, A; Folci, A; Sassone, F; Ronzitti, G; Cappelletti, G; Silani, V; Sato, S; Hattori, N; Mazzanti, M; Chieregatti, E; Mulle, C; Passafaro, M; Sassone, J Parkin regulates kainate receptors by interacting with the GluK2 subunit.
Nat Commun. 2014; 5(3):5182-5182 Doi: 10.1038/ncomms6182 [OPEN ACCESS]
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Neuhaus, A; Kooshapur, H; Wolf, J; Meyer, NH; Madl, T; Saidowsky, J; Hambruch, E; Lazam, A; Jung, M; Sattler, M; Schliebs, W; Erdmann, R A novel Pex14 protein-interacting site of human Pex5 is critical for matrix protein import into peroxisomes.
J Biol Chem. 2014; 289(1): 437-448. Doi: 10.1074/jbc.M113.499707 [OPEN ACCESS]
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Rudashevskaya, EL; Stockner, T; Trauner, M; Freissmuth, M; Chiba, P Pharmacological correction of misfolding of ABC proteins.
Drug Discov Today Technol. 2014; 12(12):e87-e94 Doi: 10.1016/j.ddtec.2014.03.009 [OPEN ACCESS]
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Step, SE; Lim, HW; Marinis, JM; Prokesch, A; Steger, DJ; You, SH; Won, KJ; Lazar, MA Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers.
Genes Dev. 2014; 28(9): 1018-1028. Doi: 10.1101/gad.237628.114 [OPEN ACCESS]
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2013

Bourgeois, B; Gilquin, B; Tellier-Lebègue, C; Östlund, C; Wu, W; Pérez, J; El Hage, P; Lallemand, F; Worman, HJ; Zinn-Justin, S Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.
Sci Signal. 2013; 6(280):ra49-ra49 Doi: 10.1126/scisignal.2003411 [OPEN ACCESS]
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Damgaard, RB; Fiil, BK; Speckmann, C; Yabal, M; zur Stadt, U; Bekker-Jensen, S; Jost, PJ; Ehl, S; Mailand, N; Gyrd-Hansen, M Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.
EMBO Mol Med. 2013; 5(8):1278-1295 Doi: 10.1002/emmm.201303090 [OPEN ACCESS]
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Derler, I; Plenk, P; Fahrner, M; Muik, M; Jardin, I; Schindl, R; Gruber, HJ; Groschner, K; Romanin, C The extended transmembrane Orai1 N-terminal (ETON) region combines binding interface and gate for Orai1 activation by STIM1.
J Biol Chem. 2013; 288(40):29025-29034 Doi: 10.1074/jbc.M113.501510 [OPEN ACCESS]
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Duszka, K; Bogner-Strauss, JG; Hackl, H; Rieder, D; Neuhold, C; Prokesch, A; Trajanoski, Z; Krogsdam, AM Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue.
Mol Endocrinol. 2013; 27(1): 135-149. Doi: 10.1210/me.2012-1248 [OPEN ACCESS]
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